Added to DL
| Player | Team | MLB DL | IBC DL |
|---|---|---|---|
| J.B. Bukauskas | 2021-05-15 | May 17 | |
| Carson Kelly | 2021-05-15 | May 17 | |
| Chris Devenski | 2021-05-15 | May 17 | |
| Asdrubal Cabrera | 2021-05-14 | May 17 | |
| Cristian Pache | DBacks | 2021-05-13 | May 17 |
| Matt Adams | 2021-05-14 | May 17 | |
| Hunter Dozier | 2021-05-14 | May 17 | |
| A.J. Pollock | 2021-05-14 | May 17 | |
| Jake Cave | 2021-05-14 | May 17 | |
| Gleyber Torres | Rangers | 2021-05-12 | May 17 |
| Phillip Evans | Rockies | 2021-05-12 | May 17 |
| Jose Alvarez | Twins | 2021-05-13 | May 17 |
| Evan White | 2021-05-14 | May 17 | |
| Ty France | 2021-05-14 | May 17 | |
| Paul DeJong | Phillies | 2021-05-12 | May 17 |
| Ryan Borucki | 2021-05-14 | May 17 |
Removed from DL
| Player | Team | MLB DL | IBC DL |
|---|---|---|---|
| Guillermo Heredia | 2021-05-01 | May 3 | |
| LaMonte Wade | 2021-04-14 | Apr 19 | |
| Josh Lindblom | Brewers | 2021-04-24 | Apr 26 |
| Omar Narvaez | Cardinals | 2021-04-30 | May 3 |
| Corbin Burnes | DBacks | 2021-04-29 | May 3 |
| Ender Inciarte | Mets | 2021-04-16 | Apr 19 |
| Cam Gallagher | RedSox | 2021-05-02 | May 3 |
| Pierce Johnson | Rockies | 2021-03-16 | Mar 22 |
| Chad Pinder | Twins | 2021-04-04 | Apr 5 |
| Ji-Man Choi | WhiteSox | 2021-03-13 | Mar 15 |
Off MLB DL, but hasn't served full time in IBC
| Player | Team | MLB DL | IBC DL |
|---|---|---|---|
| Brock Burke | 2019-09-27 | Oct 4 | |
| Anthony Rendon | Brewers | 2021-05-04 | May 10 |
| Nico Hoerner | Cubs | 2021-05-04 | May 10 |
| Luis Arraez | DBacks | 2021-05-03 | May 10 |
| Aramis Garcia | Dodgers | 2021-05-04 | May 10 |
| Dan Winkler | Dodgers | 2021-05-04 | May 10 |
| Tony Watson | Orioles | 2021-05-03 | May 10 |
| Jacob Nottingham | Padres | 2020-12-30 | Jan 3 |
| Kevin Gausman | Phillies | 2021-05-04 | May 10 |
| Merrill Kelly | RedSox | 2021-05-04 | May 10 |
| Ian Happ | Reds | 2021-05-04 | May 10 |
| Diego Castillo | Tigers | 2021-05-05 | May 10 |
| Jake Arrieta | Twins | 2021-05-04 | May 10 |
