Added to DL
| Player | Team | MLB DL | IBC DL |
|---|---|---|---|
| Shelby Miller | 2021-04-22 | Apr 26 | |
| Corey Knebel | Tigers | 2021-04-24 | Apr 26 |
| Brian Anderson | 2021-04-21 | Apr 26 | |
| Josh Lindblom | 2021-04-24 | Apr 26 | |
| Jace Peterson | 2021-04-23 | Apr 26 | |
| Brett Anderson | 2021-04-23 | Apr 26 | |
| Miguel Sano | 2021-04-21 | Apr 26 | |
| Chad Kuhl | 2021-04-22 | Apr 26 | |
| Dinelson Lamet | DBacks | 2021-04-22 | Apr 26 |
| Keone Kela | DBacks | 2021-04-22 | Apr 26 |
| Jarlin Garcia | 2021-04-24 | Apr 26 | |
| Donovan Solano | 2021-04-21 | Apr 26 | |
| John Nogowski | 2021-04-24 | Apr 26 | |
| Chris Mazza | 2021-04-24 | Apr 26 |
Removed from DL
| Player | Team | MLB DL | IBC DL |
|---|---|---|---|
| Billy Hamilton | 2021-04-08 | Apr 12 | |
| Tyler O'Neill | 2021-04-10 | Apr 12 | |
| Demarcus Evans | Astros | 2021-02-17 | Feb 22 |
| Kolten Wong | Rockies | 2021-04-08 | Apr 12 |
Off MLB DL, but hasn't served full time in IBC
| Player | Team | MLB DL | IBC DL |
|---|---|---|---|
| Brock Burke | 2019-09-27 | Oct 4 | |
| Jacob Nottingham | 2020-12-30 | Jan 3 | |
| Martin Maldonado | 2021-04-14 | Apr 19 | |
| Robel Garcia | 2021-04-14 | Apr 19 | |
| Tyler Chatwood | 2021-04-20 | Apr 26 | |
| Anthony Misiewicz | Braves | 2021-04-12 | Apr 19 |
| Drew Smyly | Brewers | 2021-04-16 | Apr 19 |
| Dylan Cease | Brewers | 2021-04-14 | Apr 19 |
| Cristian Pache | DBacks | 2021-04-13 | Apr 19 |
| Dan Winkler | Dodgers | 2021-04-12 | Apr 19 |
| Brandon Workman | Phillies | 2021-04-12 | Apr 19 |
| Jordan Romano | Pirates | 2021-04-15 | Apr 19 |
| Yordan Alvarez | Rangers | 2021-04-14 | Apr 19 |
Off MLB DL, but hasn't served full time in IBC (Team Not Determined)
| Player | MLB DL | IBC DL |
|---|---|---|
| Matt Duffy | 2021-04-13 | Apr 19 |
| Taylor Jones | 2021-04-20 | Apr 26 |
