Added to DL
| Player | Team | MLB DL | IBC DL |
|---|---|---|---|
| Hunter Harvey | Orioles | 2021-03-12 | Mar 15 |
| Franchy Cordero | Rangers | 2021-02-22 | Mar 1 |
| Chris Sale | Indians | 2020-02-12 | Feb 15 |
| Joey Votto | 2021-03-10 | Mar 15 | |
| Pedro Baez | Twins | 2021-03-09 | Mar 15 |
| Caleb Ferguson | Rockies | 2020-09-15 | Sep 20 |
| Jeff Brigham | 2021-02-17 | Feb 22 | |
| Mark Mathias | 2021-03-10 | Mar 15 | |
| Tim Lopes | 2021-03-08 | Mar 15 | |
| Luis Severino | Rangers | 2020-02-20 | Feb 22 |
| Frankie Montas | Cubs | 2021-02-17 | Feb 22 |
| Jose Soriano | 2021-02-17 | Feb 22 | |
| Trey Wingenter | 2020-07-10 | Jul 12 | |
| John Brebbia | Pirates | 2020-06-03 | Jun 7 |
| Tyler Beede | 2020-03-03 | Mar 8 | |
| Andres Munoz | Mariners | 2020-03-20 | Mar 22 |
| Oliver Drake | Phillies | 2020-10-08 | Oct 11 |
| Yonny Chirinos | Cubs | 2020-08-19 | Aug 23 |
| Colin Poche | Rockies | 2020-07-21 | Jul 26 |
| Patrick Murphy | 2021-02-18 | Feb 22 |
Added to DL (Team Not Determined)
| Player | MLB DL | IBC DL |
|---|---|---|
| Blake Cederlind | 2021-03-10 | Mar 15 |
| Mike Clevinger | 2020-11-16 | Nov 22 |
