Added to DL
| Player | Team | MLB DL | IBC DL |
|---|---|---|---|
| Nick Ahmed | 2021-04-03 | Apr 5 | |
| Zac Gallen | 2021-03-22 | Mar 29 | |
| Kole Calhoun | 2021-03-02 | Mar 8 | |
| Eduardo Rodriguez | Twins | 2021-03-26 | Mar 29 |
| Ryan Brasier | 2021-03-19 | Mar 22 | |
| Eloy Jimenez | 2021-03-24 | Mar 29 | |
| Adam Engel | 2021-03-20 | Mar 22 | |
| Jace Fry | 2021-02-17 | Feb 22 | |
| Jonathan Holder | 2021-04-01 | Apr 5 | |
| Tyson Miller | 2021-04-01 | Apr 5 | |
| Austin Romine | 2021-03-11 | Mar 15 | |
| Rowan Wick | 2021-02-16 | Feb 22 | |
| Michael Lorenzen | 2021-03-20 | Mar 22 | |
| Sonny Gray | Twins | 2021-03-14 | Mar 15 |
| Andre Scrubb | 2021-03-19 | Mar 22 | |
| Framber Valdez | 2021-03-03 | Mar 8 | |
| Josh James | 2020-10-15 | Oct 18 | |
| Justin Verlander | Yankees | 2020-07-26 | Aug 2 |
| Austin Pruitt | 2020-07-14 | Jul 19 | |
| Justin Topa | 2021-03-27 | Mar 29 | |
| Bobby Wahl | 2021-03-15 | Mar 22 | |
| Derek Fisher | Mets | 2021-03-14 | Mar 15 |
| Jacob Nottingham | 2020-12-30 | Jan 3 | |
| Josh Donaldson | Phillies | 2021-04-01 | Apr 5 |
| Drew Smith | 2021-04-01 | Apr 5 | |
| Carlos Carrasco | 2021-03-10 | Mar 15 | |
| Seth Lugo | 2021-02-13 | Feb 15 | |
| Noah Syndergaard | Astros | 2020-03-24 | Mar 29 |
| Trevor Rosenthal | 2021-04-01 | Apr 5 | |
| Mike Fiers | 2021-03-15 | Mar 22 | |
| Kyle Crick | Astros | 2021-04-01 | Apr 5 |
| Steven Brault | 2021-03-24 | Mar 29 | |
| Cody Ponce | 2021-03-06 | Mar 8 | |
| Jorge Ona | 2021-04-01 | Apr 5 | |
| Michel Baez | 2021-03-31 | Apr 5 | |
| Dan Altavilla | 2021-03-29 | Apr 5 | |
| Dinelson Lamet | 2021-03-19 | Mar 22 | |
| Pierce Johnson | 2021-03-16 | Mar 22 | |
| Austin Nola | 2021-03-14 | Mar 15 | |
| Trent Grisham | 2021-03-11 | Mar 15 | |
| Javier Guerra | 2021-03-04 | Mar 8 | |
| Matt Strahm | Athletics | 2020-10-20 | Oct 25 |
| Alex Wood | Cubs | 2021-03-13 | Mar 15 |
| Brett Phillips | 2021-03-14 | Mar 15 | |
| Ji-Man Choi | WhiteSox | 2021-03-13 | Mar 15 |
| Khris Davis | 2021-03-23 | Mar 29 | |
| Brett Martin | Braves | 2021-03-09 | Mar 15 |
| Willie Calhoun | Cubs | 2021-03-09 | Mar 15 |
| Sam Huff | 2021-02-23 | Mar 1 | |
| Demarcus Evans | 2021-02-17 | Feb 22 | |
| Joely Rodriguez | Yankees | 2021-02-17 | Feb 22 |
| Brock Burke | 2019-09-27 | Oct 4 | |
| Kirby Yates | RedSox | 2021-03-22 | Mar 29 |
| Thomas Hatch | 2021-03-17 | Mar 22 | |
| Nate Pearson | Royals | 2021-03-04 | Mar 8 |
Added to DL (Team Not Determined)
| Player | MLB DL | IBC DL |
|---|---|---|
| DJ Stewart | 2021-03-05 | Mar 8 |
| Shogo Akiyama | 2021-03-13 | Mar 15 |
| Rony Garcia | 2021-04-01 | Apr 5 |
| Austin Adams | 2021-03-29 | Apr 5 |
