Org pitching register -- Inter-league
Regular season -- as of 9/28/2025
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| Andrew Abbott* | Det | sp | 26 | 3.20 | 7 | 9 | 0 | 28 | 28 | 0 | 0 | 154.2 | 125 | 63 | 55 | 63 | 155 | 14 | 9 |
| Bryan Abreu | Sea | mr | 28 | 5.93 | 5 | 7 | 3 | 70 | 0 | 0 | 0 | 74.1 | 74 | 55 | 49 | 34 | 104 | 10 | 9 |
| Jason Adam | Ari | mr | 33 | 2.32 | 6 | 5 | 9 | 65 | 0 | 0 | 0 | 77.2 | 59 | 22 | 20 | 25 | 90 | 5 | 7 |
| Zach Agnos | NYA | mr | 24 | 5.90 | 3 | 6 | 3 | 53 | 0 | 0 | 0 | 79.1 | 87 | 56 | 52 | 32 | 69 | 20 | 3 |
| Keegan Akin* | Phi | mr | 30 | 2.61 | 6 | 4 | 7 | 70 | 0 | 0 | 0 | 79.1 | 51 | 27 | 23 | 21 | 97 | 11 | 5 |
| Jorge Alcala | | mr | 29 | 3.44 | 3 | 1 | 0 | 39 | 0 | 0 | 0 | 52.1 | 37 | 22 | 20 | 23 | 58 | 9 | 6 |
| Sandy Alcantara | Pit | sp | 29 | 2.98 | 18 | 7 | 0 | 31 | 31 | 3 | 1 | 217.2 | 196 | 80 | 72 | 59 | 204 | 13 | 16 |
| Sam Aldegheri* | Atl | sp | 23 | 8.38 | 1 | 3 | 0 | 4 | 4 | 0 | 0 | 19.1 | 24 | 18 | 18 | 5 | 17 | 2 | 1 |
| Franco Aleman | KC | mr | 25 | 5.71 | 2 | 1 | 2 | 39 | 0 | 0 | 0 | 41.0 | 38 | 28 | 26 | 26 | 33 | 4 | 1 |
| Scott Alexander* | NYN | mr | 35 | 4.47 | 3 | 2 | 0 | 28 | 3 | 0 | 0 | 44.1 | 33 | 22 | 22 | 12 | 30 | 3 | 1 |
| Tyler Alexander* | ChA | mr | 30 | 5.03 | 3 | 2 | 1 | 14 | 3 | 0 | 0 | 39.1 | 46 | 25 | 22 | 9 | 29 | 6 | 0 |
| Logan Allen* | Was | sp | 28 | 5.05 | 7 | 17 | 0 | 32 | 32 | 0 | 0 | 189.0 | 191 | 110 | 106 | 66 | 128 | 26 | 10 |
| Elvis Alvarado | Tex | mr | 26 | 3.48 | 0 | 0 | 2 | 8 | 0 | 0 | 0 | 10.1 | 8 | 5 | 4 | 3 | 12 | 1 | 0 |
| Jose Alvarado* | Ari | mr | 30 | 4.05 | 2 | 3 | 7 | 28 | 0 | 0 | 0 | 33.1 | 33 | 19 | 15 | 20 | 42 | 1 | 2 |
| Kyle Amendt | Atl | mr | 25 | 6.28 | 2 | 3 | 1 | 32 | 0 | 0 | 0 | 38.2 | 32 | 29 | 27 | 21 | 41 | 9 | 1 |
| Ian Anderson | NYA | sp | 27 | 5.73 | 5 | 7 | 1 | 23 | 10 | 0 | 0 | 66.0 | 75 | 47 | 42 | 38 | 49 | 8 | 3 |
| Tyler Anderson* | Tor | sp | 35 | 3.98 | 3 | 6 | 0 | 16 | 16 | 0 | 0 | 95.0 | 87 | 46 | 42 | 28 | 76 | 6 | 2 |
| Shawn Armstrong | Ari | mr | 34 | 4.71 | 1 | 1 | 4 | 24 | 0 | 0 | 0 | 28.2 | 25 | 16 | 15 | 13 | 27 | 2 | 0 |
| Spencer Arrighetti | Phi | sp | 25 | 2.86 | 2 | 1 | 0 | 4 | 4 | 0 | 0 | 22.0 | 20 | 9 | 7 | 8 | 22 | 3 | 3 |
| Aaron Ashby* | Sea | mr | 27 | 7.55 | 1 | 6 | 1 | 19 | 9 | 0 | 0 | 53.2 | 65 | 46 | 45 | 40 | 67 | 9 | 4 |
| Braxton Ashcraft | Atl | sp | 25 | 4.02 | 4 | 10 | 0 | 36 | 24 | 0 | 0 | 150.0 | 137 | 74 | 67 | 37 | 124 | 17 | 5 |
| Graham Ashcraft | Was | sp | 27 | 3.35 | 4 | 1 | 0 | 39 | 1 | 0 | 0 | 51.0 | 39 | 22 | 19 | 17 | 44 | 3 | 4 |
| Sam Bachman | Tor | sp | 25 | 3.32 | 4 | 1 | 1 | 32 | 1 | 0 | 0 | 43.1 | 37 | 16 | 16 | 18 | 35 | 2 | 5 |
| Henry Baez | Tor | sp | 22 | 7.05 | 1 | 6 | 0 | 12 | 10 | 0 | 0 | 52.1 | 76 | 49 | 41 | 22 | 32 | 12 | 3 |
| Bryan Baker | Col | mr | 30 | 4.76 | 0 | 2 | 0 | 31 | 0 | 0 | 0 | 39.2 | 39 | 23 | 21 | 16 | 30 | 3 | 3 |
| Tanner Banks* | SD | mr | 33 | 3.39 | 8 | 11 | 7 | 72 | 0 | 0 | 0 | 85.0 | 77 | 41 | 32 | 28 | 87 | 7 | 3 |
| Scott Barlow | ChN | mr | 32 | 3.72 | 3 | 3 | 14 | 71 | 0 | 0 | 0 | 87.0 | 63 | 40 | 36 | 48 | 91 | 13 | 8 |
| Mason Barnett | StL | sp | 24 | 4.47 | 5 | 17 | 0 | 36 | 32 | 0 | 0 | 179.0 | 169 | 110 | 89 | 75 | 156 | 18 | 11 |
| Chris Bassitt | Mil | sp | 36 | 5.02 | 12 | 14 | 0 | 33 | 33 | 1 | 1 | 177.1 | 183 | 116 | 99 | 90 | 148 | 22 | 15 |
| Brady Basso* | Min | sp | 27 | 2.68 | 3 | 3 | 1 | 47 | 0 | 0 | 0 | 53.2 | 49 | 25 | 16 | 14 | 40 | 7 | 6 |
| Felix Bautista | ChN | cl | 30 | 1.66 | 4 | 4 | 15 | 40 | 0 | 0 | 0 | 54.1 | 27 | 16 | 10 | 20 | 68 | 3 | 0 |
| Shane Baz | Bal | sp | 26 | 3.51 | 10 | 11 | 0 | 39 | 37 | 0 | 0 | 187.0 | 168 | 80 | 73 | 76 | 182 | 10 | 11 |
| Eduard Bazardo | Pit | mr | 29 | 5.79 | 3 | 3 | 1 | 57 | 0 | 0 | 0 | 70.0 | 78 | 51 | 45 | 21 | 73 | 8 | 3 |
| Tristan Beck | SF | mr | 29 | 3.85 | 6 | 5 | 7 | 46 | 5 | 1 | 1 | 110.0 | 99 | 63 | 47 | 39 | 107 | 14 | 9 |
| Ian Bedell | ChA | sp | 25 | 8.66 | 1 | 4 | 2 | 35 | 0 | 0 | 0 | 35.1 | 53 | 38 | 34 | 18 | 31 | 11 | 2 |
| David Bednar | LAA | cl | 30 | 2.10 | 5 | 1 | 3 | 63 | 0 | 0 | 0 | 68.2 | 53 | 22 | 16 | 17 | 80 | 5 | 4 |
| Jalen Beeks* | LAN | mr | 31 | 4.61 | 5 | 1 | 2 | 79 | 2 | 0 | 0 | 123.0 | 136 | 69 | 63 | 53 | 99 | 11 | 9 |
| Clayton Beeter | Col | sp | 26 | 6.22 | 1 | 10 | 0 | 22 | 20 | 0 | 0 | 98.1 | 109 | 71 | 68 | 47 | 109 | 16 | 3 |
| Nigel Belgrave | | mr | 23 | 3.74 | 2 | 1 | 1 | 35 | 0 | 0 | 0 | 45.2 | 28 | 20 | 19 | 28 | 39 | 5 | 4 |
| Brayan Bello | Mil | sp | 26 | 4.24 | 11 | 9 | 0 | 28 | 28 | 0 | 0 | 167.2 | 148 | 81 | 79 | 52 | 150 | 17 | 15 |
| Valente Bellozo | Tor | sp | 25 | 3.82 | 2 | 3 | 1 | 40 | 2 | 0 | 0 | 63.2 | 67 | 31 | 27 | 21 | 46 | 7 | 3 |
| Anthony Bender | Mil | mr | 30 | 4.17 | 2 | 3 | 7 | 38 | 0 | 0 | 0 | 41.0 | 36 | 20 | 19 | 21 | 40 | 2 | 7 |
| Ryan Bergert | Hou | sp | 25 | 6.89 | 0 | 2 | 0 | 21 | 0 | 0 | 0 | 31.1 | 41 | 31 | 24 | 13 | 28 | 8 | 2 |
| Brennan Bernardino* | | mr | 33 | 3.47 | 7 | 2 | 3 | 50 | 2 | 0 | 0 | 57.0 | 53 | 24 | 22 | 17 | 55 | 5 | 4 |
| Jose Berrios | | sp | 31 | 4.99 | 8 | 10 | 0 | 37 | 24 | 1 | 0 | 169.2 | 165 | 108 | 94 | 41 | 154 | 22 | 11 |
| Prelander Berroa | SF | mr | 25 | 6.16 | 3 | 8 | 0 | 28 | 3 | 0 | 0 | 57.0 | 61 | 43 | 39 | 36 | 70 | 11 | 2 |
| Tanner Bibee | Was | sp | 26 | 3.42 | 14 | 8 | 0 | 33 | 33 | 0 | 0 | 197.1 | 166 | 84 | 75 | 51 | 208 | 30 | 9 |
| Phil Bickford | ChN | mr | 29 | 3.25 | 13 | 5 | 2 | 35 | 25 | 0 | 0 | 149.1 | 97 | 57 | 54 | 36 | 145 | 23 | 7 |
| Osvaldo Bido | | sp | 29 | 5.60 | 6 | 10 | 0 | 28 | 27 | 0 | 0 | 138.1 | 128 | 93 | 86 | 73 | 134 | 14 | 4 |
| Shane Bieber | Hou | sp | 30 | 3.67 | 2 | 3 | 0 | 6 | 6 | 0 | 0 | 34.1 | 34 | 21 | 14 | 15 | 36 | 3 | 0 |
| Hayden Birdsong | Bos | sp | 23 | 0.00 | 1 | 1 | 0 | 5 | 0 | 0 | 0 | 7.2 | 8 | 3 | 0 | 7 | 3 | 0 | 1 |
| Ronel Blanco | Col | sp | 31 | 3.38 | 1 | 1 | 2 | 21 | 2 | 0 | 0 | 42.2 | 34 | 20 | 16 | 17 | 40 | 4 | 4 |
| A.J. Blubaugh | | sp | 24 | 4.06 | 8 | 7 | 0 | 31 | 23 | 0 | 0 | 137.1 | 112 | 64 | 62 | 41 | 123 | 15 | 9 |
| Ryan Borucki* | LAN | mr | 31 | 2.94 | 2 | 3 | 1 | 47 | 0 | 0 | 0 | 64.1 | 52 | 30 | 21 | 44 | 70 | 8 | 1 |
| Matt Boyd* | Tex | sp | 34 | 2.85 | 11 | 2 | 0 | 26 | 26 | 0 | 0 | 148.2 | 99 | 49 | 47 | 43 | 145 | 20 | 11 |
| Joe Boyle | NYA | sp | 25 | 9.66 | 4 | 21 | 0 | 43 | 28 | 0 | 0 | 137.0 | 145 | 168 | 147 | 158 | 152 | 21 | 6 |
| Kyle Bradish | Bal | sp | 28 | 1.24 | 4 | 0 | 0 | 7 | 7 | 1 | 1 | 50.2 | 31 | 8 | 7 | 9 | 61 | 1 | 3 |
| Taj Bradley | | sp | 24 | 4.04 | 9 | 13 | 0 | 31 | 31 | 0 | 0 | 169.1 | 150 | 80 | 76 | 63 | 178 | 24 | 10 |
| Matt Brash | Col | mr | 27 | 4.53 | 6 | 4 | 1 | 35 | 15 | 0 | 0 | 95.1 | 84 | 49 | 48 | 47 | 135 | 8 | 3 |
| Ryan Brasier | Pit | mr | 37 | 3.10 | 5 | 2 | 2 | 39 | 0 | 0 | 0 | 40.2 | 38 | 17 | 14 | 6 | 33 | 4 | 1 |
| Mitch Bratt* | StL | sp | 21 | 3.57 | 4 | 3 | 1 | 103 | 1 | 0 | 0 | 106.0 | 87 | 44 | 42 | 29 | 82 | 14 | 1 |
| Lucas Braun | | sp | 23 | 6.33 | 0 | 4 | 1 | 15 | 6 | 0 | 0 | 42.2 | 55 | 34 | 30 | 17 | 43 | 4 | 5 |
| Huascar Brazoban | NYN | mr | 35 | 3.90 | 10 | 2 | 4 | 70 | 1 | 0 | 0 | 97.0 | 81 | 47 | 42 | 52 | 96 | 6 | 11 |
| John Brebbia | ChA | mr | 35 | 3.98 | 2 | 7 | 4 | 57 | 1 | 0 | 0 | 54.1 | 51 | 26 | 24 | 28 | 62 | 4 | 4 |
| Jhony Brito | ChA | mr | 27 | 3.24 | 7 | 7 | 0 | 23 | 23 | 0 | 0 | 144.2 | 115 | 54 | 52 | 31 | 105 | 18 | 7 |
| Ben Brown | Sea | sp | 25 | 4.05 | 10 | 9 | 0 | 32 | 32 | 0 | 0 | 162.1 | 129 | 76 | 73 | 77 | 180 | 18 | 6 |
| Hunter Brown | Mia | sp | 26 | 3.45 | 14 | 6 | 0 | 36 | 36 | 0 | 0 | 201.0 | 172 | 78 | 77 | 67 | 222 | 19 | 11 |
| Kris Bubic* | Tex | mr | 27 | 2.78 | 5 | 2 | 1 | 27 | 12 | 0 | 0 | 81.0 | 59 | 28 | 25 | 28 | 79 | 5 | 8 |
| Walker Buehler | Phi | sp | 30 | 2.72 | 9 | 8 | 0 | 28 | 28 | 0 | 0 | 162.0 | 125 | 57 | 49 | 31 | 150 | 16 | 4 |
| J.B. Bukauskas | LAN | mr | 28 | 3.38 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 2.2 | 3 | 1 | 1 | 0 | 3 | 0 | 0 |
| Aaron Bummer* | | mr | 31 | 2.28 | 5 | 8 | 18 | 68 | 0 | 0 | 0 | 75.0 | 58 | 22 | 19 | 20 | 92 | 4 | 4 |
| Brock Burke* | | mr | 28 | 2.51 | 9 | 5 | 4 | 60 | 0 | 0 | 0 | 93.1 | 82 | 33 | 26 | 34 | 98 | 7 | 11 |
| Sean Burke | LAA | sp | 25 | 5.57 | 1 | 0 | 1 | 27 | 0 | 0 | 0 | 32.1 | 36 | 20 | 20 | 13 | 36 | 6 | 2 |
| Corbin Burnes | Ari | sp | 30 | 3.28 | 5 | 5 | 0 | 15 | 15 | 1 | 1 | 93.1 | 72 | 46 | 34 | 24 | 93 | 5 | 5 |
| Tanner Burns | ChA | mr | 26 | 5.83 | 3 | 19 | 0 | 44 | 25 | 0 | 0 | 151.1 | 150 | 103 | 98 | 94 | 122 | 19 | 9 |
| Ryan Burr | KC | mr | 31 | 0.96 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 9.1 | 3 | 1 | 1 | 2 | 17 | 1 | 0 |
| Mike Burrows | Sea | sp | 25 | 9.00 | 1 | 0 | 1 | 7 | 0 | 0 | 0 | 7.0 | 9 | 7 | 7 | 2 | 7 | 1 | 0 |
| Jose Butto | | mr | 27 | 4.88 | 6 | 4 | 6 | 52 | 1 | 0 | 0 | 66.1 | 63 | 39 | 36 | 43 | 58 | 11 | 7 |
| Edward Cabrera | Atl | sp | 27 | 4.37 | 7 | 6 | 0 | 25 | 24 | 0 | 0 | 111.1 | 93 | 57 | 54 | 53 | 119 | 16 | 6 |
| Jean Cabrera | Tor | sp | 23 | 7.17 | 3 | 3 | 1 | 32 | 3 | 0 | 0 | 47.2 | 56 | 38 | 38 | 26 | 38 | 8 | 2 |
| Noah Cameron* | Cin | sp | 25 | 3.65 | 6 | 8 | 0 | 27 | 27 | 0 | 0 | 135.2 | 114 | 65 | 55 | 42 | 117 | 15 | 5 |
| Griffin Canning | StL | sp | 29 | 7.68 | 3 | 2 | 3 | 62 | 0 | 0 | 0 | 65.2 | 76 | 63 | 56 | 30 | 42 | 13 | 2 |
| Jonathan Cannon | SD | sp | 24 | 4.09 | 2 | 1 | 1 | 16 | 0 | 0 | 0 | 22.0 | 25 | 11 | 10 | 11 | 20 | 1 | 2 |
| Yennier Cano | ChN | mr | 31 | 3.26 | 7 | 6 | 2 | 60 | 1 | 0 | 0 | 94.0 | 58 | 35 | 34 | 35 | 89 | 5 | 6 |
| Joey Cantillo* | SF | sp | 25 | 7.22 | 3 | 13 | 0 | 25 | 22 | 0 | 0 | 104.2 | 119 | 90 | 84 | 72 | 118 | 11 | 5 |
| Ben Casparius | ChA | sp | 26 | 7.39 | 2 | 8 | 1 | 29 | 10 | 0 | 0 | 70.2 | 77 | 59 | 58 | 47 | 66 | 12 | 3 |
| Jose Castillo* | ChN | mr | 29 | 3.00 | 2 | 1 | 0 | 7 | 2 | 0 | 0 | 18.0 | 14 | 10 | 6 | 11 | 13 | 2 | 1 |
| Luis Castillo | Bos | sp | 32 | 2.36 | 16 | 6 | 0 | 33 | 33 | 1 | 1 | 206.0 | 162 | 57 | 54 | 62 | 226 | 13 | 13 |
| Miguel Castro | Min | mr | 30 | 5.63 | 3 | 2 | 2 | 23 | 0 | 0 | 0 | 32.0 | 32 | 22 | 20 | 15 | 32 | 6 | 2 |
| Cade Cavalli | Sac | sp | 26 | 3.49 | 4 | 10 | 0 | 25 | 25 | 1 | 1 | 129.0 | 105 | 55 | 50 | 52 | 135 | 13 | 6 |
| Dylan Cease | Mil | sp | 29 | 3.72 | 12 | 6 | 0 | 33 | 33 | 0 | 0 | 181.1 | 139 | 81 | 75 | 77 | 206 | 18 | 6 |
| Slade Cecconi | SD | sp | 26 | 4.12 | 9 | 6 | 0 | 24 | 24 | 1 | 1 | 142.0 | 128 | 69 | 65 | 42 | 100 | 17 | 11 |
| Andrew Chafin* | Sac | mr | 35 | 3.96 | 0 | 1 | 2 | 33 | 0 | 0 | 0 | 25.0 | 31 | 12 | 11 | 17 | 29 | 2 | 3 |
| Bubba Chandler | SF | sp | 22 | 4.03 | 3 | 4 | 0 | 17 | 12 | 0 | 0 | 73.2 | 70 | 41 | 33 | 40 | 67 | 7 | 6 |
| Aroldis Chapman* | LAA | mr | 37 | 4.71 | 6 | 3 | 6 | 60 | 0 | 0 | 0 | 65.0 | 57 | 35 | 34 | 45 | 96 | 14 | 1 |
| Jesse Chavez | ChA | mr | 41 | 4.43 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 20.1 | 19 | 12 | 10 | 8 | 18 | 2 | 2 |
| Po-Yu Chen | StL | sp | 23 | 3.51 | 2 | 1 | 1 | 23 | 0 | 0 | 0 | 25.2 | 31 | 12 | 10 | 5 | 16 | 2 | 2 |
| Jack Choate* | ChN | sp | 24 | 0.00 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1.1 | 0 | 0 | 0 | 1 | 2 | 0 | 0 |
| Marc Church | Mil | mr | 24 | 5.35 | 2 | 0 | 1 | 27 | 0 | 0 | 0 | 37.0 | 33 | 23 | 22 | 16 | 37 | 6 | 2 |
| Aaron Civale | Min | sp | 30 | 6.92 | 0 | 5 | 0 | 6 | 6 | 0 | 0 | 26.0 | 24 | 21 | 20 | 15 | 26 | 6 | 2 |
| Emmanuel Clase | Sea | cl | 27 | 3.49 | 2 | 11 | 15 | 40 | 0 | 0 | 0 | 49.0 | 42 | 29 | 19 | 10 | 52 | 3 | 0 |
| Garrett Cleavinger* | Ari | mr | 31 | 4.44 | 7 | 6 | 6 | 66 | 0 | 0 | 0 | 81.0 | 64 | 43 | 40 | 41 | 84 | 8 | 9 |
| Adisyn Coffey | Hou | mr | 26 | 6.95 | 1 | 1 | 2 | 19 | 0 | 0 | 0 | 22.0 | 28 | 21 | 17 | 15 | 11 | 4 | 2 |
| Roansy Contreras | Det | mr | 25 | 3.66 | 8 | 11 | 4 | 54 | 23 | 0 | 0 | 174.2 | 148 | 82 | 71 | 58 | 163 | 22 | 8 |
| Nestor Cortes* | | sp | 30 | 3.69 | 3 | 2 | 0 | 13 | 10 | 0 | 0 | 61.0 | 53 | 25 | 25 | 19 | 53 | 6 | 2 |
| Danny Coulombe* | Det | mr | 35 | 3.77 | 3 | 4 | 1 | 70 | 0 | 0 | 0 | 71.2 | 57 | 31 | 30 | 24 | 76 | 10 | 3 |
| Austin Cox* | ChA | mr | 28 | 3.55 | 1 | 2 | 1 | 15 | 3 | 0 | 0 | 45.2 | 46 | 20 | 18 | 26 | 32 | 3 | 10 |
| Cooper Criswell | Mil | sp | 28 | 6.15 | 1 | 3 | 1 | 29 | 0 | 0 | 0 | 33.2 | 41 | 28 | 23 | 8 | 25 | 7 | 4 |
| Garrett Crochet* | Cle | sp | 26 | 2.55 | 13 | 4 | 0 | 32 | 32 | 0 | 0 | 166.0 | 127 | 49 | 47 | 56 | 223 | 7 | 13 |
| Declan Cronin | Tam | mr | 27 | 2.48 | 5 | 1 | 2 | 26 | 0 | 0 | 0 | 36.1 | 35 | 11 | 10 | 8 | 31 | 4 | 7 |
| Fernando Cruz | Hou | mr | 35 | 2.81 | 9 | 3 | 0 | 25 | 25 | 0 | 0 | 125.0 | 86 | 42 | 39 | 67 | 173 | 11 | 6 |
| Yoniel Curet | Sac | sp | 22 | 8.57 | 0 | 0 | 0 | 16 | 0 | 0 | 0 | 21.0 | 21 | 20 | 20 | 15 | 26 | 4 | 2 |
| Xzavion Curry | SF | sp | 26 | 5.37 | 0 | 6 | 0 | 17 | 8 | 0 | 0 | 68.2 | 77 | 42 | 41 | 24 | 54 | 15 | 3 |
| Caden Dana | NYA | sp | 21 | 5.40 | 0 | 3 | 0 | 4 | 4 | 0 | 0 | 21.2 | 24 | 17 | 13 | 3 | 18 | 3 | 1 |
| Davis Daniel | Phi | sp | 28 | 4.06 | 7 | 5 | 0 | 19 | 19 | 0 | 0 | 106.1 | 105 | 52 | 48 | 32 | 74 | 14 | 5 |
| Hagen Danner | Cin | mr | 26 | 6.48 | 0 | 0 | 1 | 24 | 0 | 0 | 0 | 33.1 | 37 | 24 | 24 | 12 | 38 | 5 | 1 |
| Yu Darvish | | sp | 38 | 3.41 | 4 | 4 | 0 | 11 | 11 | 0 | 0 | 63.1 | 51 | 30 | 24 | 15 | 62 | 9 | 1 |
| Duncan Davitt | StL | sp | 25 | 4.84 | 2 | 3 | 1 | 55 | 6 | 0 | 0 | 89.1 | 95 | 52 | 48 | 33 | 68 | 12 | 4 |
| Enyel de los Santos | Mil | mr | 29 | 4.08 | 1 | 1 | 2 | 32 | 0 | 0 | 0 | 35.1 | 33 | 17 | 16 | 19 | 34 | 6 | 1 |
| Yerry de los Santos | NYA | mr | 27 | 3.46 | 1 | 1 | 4 | 22 | 0 | 0 | 0 | 41.2 | 39 | 22 | 16 | 12 | 29 | 6 | 4 |
| Jacob deGrom | | sp | 37 | 3.52 | 13 | 6 | 0 | 32 | 32 | 0 | 0 | 166.0 | 138 | 68 | 65 | 43 | 221 | 18 | 3 |
| Reid Detmers* | | sp | 25 | 4.31 | 0 | 3 | 0 | 10 | 4 | 0 | 0 | 31.1 | 34 | 16 | 15 | 16 | 30 | 3 | 3 |
| Alexis Diaz | Det | cl | 28 | 3.51 | 3 | 5 | 1 | 65 | 0 | 0 | 0 | 84.2 | 62 | 41 | 33 | 48 | 80 | 3 | 8 |
| Edwin Diaz | LAA | cl | 31 | 4.30 | 5 | 6 | 33 | 60 | 0 | 0 | 0 | 69.0 | 61 | 40 | 33 | 27 | 111 | 10 | 4 |
| Miguel Diaz | | mr | 30 | 3.72 | 3 | 4 | 2 | 62 | 0 | 0 | 0 | 75.0 | 66 | 34 | 31 | 22 | 67 | 5 | 5 |
| Yilber Diaz | Hou | sp | 24 | 4.19 | 7 | 7 | 0 | 27 | 23 | 0 | 0 | 137.1 | 115 | 70 | 64 | 65 | 108 | 15 | 11 |
| Hunter Dobbins | Sea | sp | 25 | 3.38 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 16.0 | 13 | 7 | 6 | 8 | 14 | 0 | 2 |
| Dylan Dodd* | Sac | sp | 27 | 6.23 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 8.2 | 11 | 6 | 6 | 3 | 9 | 2 | 1 |
| Chase Dollander | Ari | sp | 23 | 4.47 | 5 | 4 | 0 | 27 | 6 | 0 | 0 | 58.1 | 58 | 33 | 29 | 29 | 53 | 3 | 2 |
| Seranthony Dominguez | Was | mr | 30 | 4.37 | 6 | 4 | 6 | 68 | 0 | 0 | 0 | 80.1 | 60 | 43 | 39 | 38 | 86 | 12 | 7 |
| Camilo Doval | Cle | cl | 27 | 2.97 | 2 | 4 | 28 | 56 | 0 | 0 | 0 | 57.2 | 43 | 25 | 19 | 22 | 76 | 4 | 4 |
| Jack Dreyer* | KC | mr | 26 | 4.36 | 6 | 10 | 4 | 98 | 0 | 0 | 0 | 119.2 | 101 | 63 | 58 | 43 | 141 | 11 | 5 |
| Jhoan Duran | Sea | cl | 27 | 2.67 | 7 | 2 | 11 | 68 | 0 | 0 | 0 | 91.0 | 58 | 29 | 27 | 26 | 116 | 7 | 2 |
| Zach Eflin | | sp | 31 | 4.88 | 5 | 7 | 0 | 20 | 18 | 0 | 0 | 114.1 | 131 | 65 | 62 | 28 | 95 | 12 | 3 |
| Brandon Eisert* | Det | mr | 27 | 6.04 | 2 | 4 | 4 | 38 | 2 | 0 | 0 | 50.2 | 62 | 35 | 34 | 23 | 48 | 4 | 6 |
| Bryce Elder | NYN | sp | 26 | 3.48 | 12 | 13 | 0 | 33 | 33 | 2 | 1 | 209.1 | 170 | 86 | 81 | 90 | 146 | 21 | 19 |
| Magnus Ellerts | Atl | mr | 24 | 5.48 | 6 | 3 | 2 | 66 | 0 | 0 | 0 | 70.2 | 83 | 46 | 43 | 37 | 81 | 11 | 8 |
| Mason Englert | Atl | mr | 25 | 9.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 3 | 1 | 1 | 0 | 0 | 0 | 0 |
| Nic Enright | Cin | mr | 28 | 3.35 | 4 | 3 | 0 | 47 | 7 | 0 | 0 | 86.0 | 93 | 35 | 32 | 30 | 80 | 7 | 7 |
| Nathan Eovaldi | Sac | sp | 35 | 2.05 | 7 | 2 | 0 | 12 | 12 | 1 | 1 | 79.0 | 60 | 18 | 18 | 16 | 72 | 3 | 8 |
| Lucas Erceg | LAN | mr | 30 | 3.35 | 5 | 6 | 34 | 66 | 0 | 0 | 0 | 78.0 | 63 | 37 | 29 | 23 | 85 | 10 | 4 |
| Carlos Estevez | | cl | 32 | 3.78 | 8 | 3 | 2 | 63 | 1 | 0 | 0 | 81.0 | 67 | 37 | 34 | 28 | 88 | 13 | 3 |
| Jeremiah Estrada | Sea | mr | 26 | 4.41 | 5 | 2 | 1 | 71 | 0 | 0 | 0 | 79.2 | 68 | 42 | 39 | 40 | 106 | 8 | 2 |
| Logan Evans | Tor | sp | 24 | 5.12 | 2 | 7 | 1 | 28 | 4 | 0 | 0 | 45.2 | 43 | 32 | 26 | 25 | 33 | 3 | 5 |
| Pete Fairbanks | ChN | cl | 31 | 3.06 | 2 | 2 | 4 | 43 | 3 | 0 | 0 | 67.2 | 53 | 27 | 23 | 29 | 69 | 8 | 4 |
| Bailey Falter* | KC | sp | 28 | 4.83 | 5 | 6 | 0 | 18 | 18 | 0 | 0 | 98.2 | 108 | 53 | 53 | 27 | 75 | 10 | 9 |
| Calvin Faucher | | mr | 29 | 4.48 | 1 | 6 | 15 | 62 | 0 | 0 | 0 | 68.1 | 75 | 41 | 34 | 35 | 65 | 4 | 6 |
| Erick Fedde | Tam | sp | 32 | 6.07 | 5 | 5 | 0 | 15 | 15 | 0 | 0 | 66.2 | 76 | 50 | 45 | 34 | 72 | 8 | 4 |
| Ryan Feltner | Mil | sp | 28 | 4.78 | 3 | 3 | 0 | 7 | 7 | 1 | 1 | 43.1 | 36 | 24 | 23 | 12 | 36 | 7 | 1 |
| Caleb Ferguson* | LAA | mr | 28 | 4.19 | 3 | 4 | 1 | 37 | 5 | 0 | 0 | 58.0 | 59 | 28 | 27 | 19 | 51 | 7 | 4 |
| Ryan Fernandez | | mr | 27 | 6.61 | 3 | 2 | 1 | 40 | 0 | 0 | 0 | 49.0 | 51 | 39 | 36 | 22 | 51 | 10 | 2 |
| Jose A. Ferrer* | Hou | mr | 25 | 3.38 | 7 | 2 | 3 | 71 | 0 | 0 | 0 | 88.0 | 77 | 37 | 33 | 22 | 82 | 6 | 9 |
| David Festa | Hou | sp | 25 | 5.47 | 2 | 7 | 1 | 23 | 14 | 0 | 0 | 72.1 | 83 | 49 | 44 | 36 | 77 | 8 | 4 |
| Kyle Finnegan | NYN | cl | 33 | 3.39 | 3 | 3 | 2 | 37 | 0 | 0 | 0 | 58.1 | 50 | 27 | 22 | 21 | 61 | 11 | 5 |
| Braydon Fisher | LAN | mr | 24 | 6.24 | 7 | 6 | 5 | 73 | 5 | 0 | 0 | 96.2 | 98 | 71 | 67 | 56 | 86 | 12 | 4 |
| Jack Flaherty | | sp | 29 | 3.73 | 9 | 9 | 0 | 28 | 28 | 1 | 1 | 157.0 | 129 | 69 | 65 | 47 | 187 | 22 | 11 |
| Jose Fleury | StL | sp | 23 | 5.93 | 3 | 15 | 2 | 66 | 14 | 0 | 0 | 136.2 | 141 | 107 | 90 | 65 | 116 | 23 | 7 |
| Dylan Floro | Was | mr | 34 | 2.15 | 4 | 2 | 11 | 56 | 0 | 0 | 0 | 71.0 | 61 | 23 | 17 | 17 | 62 | 2 | 4 |
| Mason Fluharty* | | mr | 23 | 4.47 | 3 | 3 | 7 | 62 | 0 | 0 | 0 | 98.2 | 86 | 52 | 49 | 37 | 93 | 13 | 8 |
| Jason Foley | Sac | cl | 29 | 1.23 | 0 | 2 | 2 | 8 | 0 | 0 | 0 | 7.1 | 7 | 3 | 1 | 5 | 11 | 0 | 0 |
| J.P. France | KC | sp | 30 | 3.15 | 3 | 1 | 0 | 7 | 7 | 0 | 0 | 40.0 | 36 | 15 | 14 | 18 | 30 | 6 | 3 |
| Bowden Francis | Tex | sp | 29 | 3.32 | 8 | 1 | 0 | 12 | 12 | 1 | 0 | 78.2 | 57 | 31 | 29 | 8 | 71 | 10 | 3 |
| Max Fried* | Ari | sp | 31 | 4.21 | 15 | 10 | 0 | 35 | 35 | 2 | 1 | 220.0 | 207 | 112 | 103 | 69 | 193 | 15 | 14 |
| Kody Funderburk* | | mr | 28 | 5.30 | 2 | 5 | 0 | 35 | 0 | 0 | 0 | 37.1 | 42 | 26 | 22 | 17 | 32 | 4 | 2 |
| Hunter Gaddis | Bos | mr | 27 | 4.11 | 6 | 10 | 2 | 49 | 18 | 0 | 0 | 146.2 | 128 | 77 | 67 | 39 | 144 | 21 | 3 |
| Matt Gage* | NYA | mr | 32 | 2.45 | 1 | 0 | 1 | 8 | 0 | 0 | 0 | 7.1 | 11 | 8 | 2 | 6 | 6 | 0 | 2 |
| Zac Gallen | Mia | sp | 29 | 2.98 | 18 | 4 | 0 | 36 | 36 | 1 | 1 | 223.2 | 186 | 76 | 74 | 81 | 211 | 21 | 15 |
| Brandyn Garcia* | Bal | sp | 25 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0.1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
| Luis A. Garcia | | mr | 38 | 4.02 | 5 | 5 | 2 | 60 | 0 | 0 | 0 | 69.1 | 87 | 36 | 31 | 24 | 64 | 3 | 5 |
| Robert Garcia* | Was | mr | 29 | 2.39 | 2 | 3 | 7 | 68 | 0 | 0 | 0 | 75.1 | 53 | 27 | 20 | 26 | 95 | 4 | 6 |
| Yimi Garcia | Hou | mr | 34 | 3.75 | 2 | 3 | 4 | 22 | 0 | 0 | 0 | 24.0 | 19 | 12 | 10 | 9 | 22 | 5 | 2 |
| Reed Garrett | NYN | mr | 32 | 3.25 | 4 | 7 | 3 | 66 | 0 | 0 | 0 | 83.0 | 64 | 34 | 30 | 41 | 110 | 4 | 6 |
| Robert Gasser* | Cin | sp | 26 | 4.13 | 1 | 1 | 0 | 5 | 5 | 0 | 0 | 28.1 | 23 | 16 | 13 | 12 | 27 | 1 | 2 |
| Kevin Gausman | Min | sp | 34 | 4.18 | 12 | 10 | 0 | 32 | 32 | 0 | 0 | 194.0 | 182 | 103 | 90 | 48 | 179 | 28 | 4 |
| Paul Gervase | | mr | 25 | 4.59 | 3 | 4 | 4 | 66 | 0 | 0 | 0 | 86.1 | 73 | 48 | 44 | 56 | 92 | 8 | 2 |
| Kyle Gibson | Bos | sp | 37 | 3.52 | 4 | 1 | 0 | 6 | 6 | 1 | 1 | 38.1 | 34 | 16 | 15 | 18 | 29 | 6 | 2 |
| Luis Gil | SD | sp | 27 | 3.18 | 3 | 1 | 0 | 8 | 8 | 0 | 0 | 39.2 | 29 | 19 | 14 | 19 | 48 | 6 | 3 |
| Logan Gilbert | Ari | sp | 28 | 4.79 | 6 | 11 | 0 | 25 | 25 | 0 | 0 | 142.2 | 145 | 83 | 76 | 36 | 160 | 12 | 8 |
| Kevin Ginkel | | mr | 31 | 2.51 | 2 | 5 | 5 | 38 | 0 | 0 | 0 | 46.2 | 35 | 18 | 13 | 18 | 47 | 1 | 2 |
| J.T. Ginn | | sp | 26 | 4.84 | 5 | 3 | 0 | 39 | 4 | 0 | 0 | 61.1 | 66 | 37 | 33 | 28 | 47 | 5 | 8 |
| Lucas Giolito | Mia | sp | 30 | 5.40 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 18.1 | 19 | 13 | 11 | 8 | 19 | 2 | 1 |
| Sawyer Gipson-Long | Mia | sp | 27 | 6.75 | 1 | 2 | 0 | 6 | 6 | 0 | 0 | 28.0 | 33 | 21 | 21 | 9 | 32 | 7 | 2 |
| Tyler Glasnow | Sea | sp | 31 | 3.74 | 5 | 7 | 0 | 21 | 21 | 0 | 0 | 118.0 | 106 | 54 | 49 | 42 | 138 | 14 | 2 |
| Yoendrys Gomez | SD | sp | 25 | 1.50 | 2 | 0 | 0 | 11 | 0 | 0 | 0 | 12.0 | 7 | 4 | 2 | 8 | 13 | 1 | 1 |
| Tony Gonsolin | Tex | sp | 31 | 2.77 | 3 | 1 | 0 | 7 | 7 | 0 | 0 | 39.0 | 31 | 12 | 12 | 9 | 32 | 5 | 3 |
| Colton Gordon* | | sp | 26 | 3.84 | 7 | 4 | 0 | 27 | 19 | 0 | 0 | 119.2 | 103 | 64 | 51 | 41 | 113 | 15 | 2 |
| MacKenzie Gore* | | sp | 26 | 4.19 | 8 | 6 | 0 | 28 | 28 | 0 | 0 | 141.2 | 125 | 77 | 66 | 58 | 143 | 17 | 11 |
| Gordon Graceffo | Min | sp | 25 | 5.35 | 1 | 2 | 4 | 29 | 0 | 0 | 0 | 35.1 | 40 | 23 | 21 | 19 | 31 | 4 | 4 |
| Andre Granillo | NYA | mr | 25 | 7.55 | 1 | 11 | 3 | 47 | 0 | 0 | 0 | 64.1 | 78 | 60 | 54 | 48 | 61 | 17 | 2 |
| Kendall Graveman | NYN | mr | 34 | 3.18 | 1 | 0 | 0 | 12 | 2 | 0 | 0 | 22.2 | 15 | 9 | 8 | 13 | 22 | 5 | 1 |
| Jon Gray | Sac | sp | 33 | 2.12 | 2 | 1 | 0 | 5 | 5 | 0 | 0 | 34.0 | 20 | 8 | 8 | 9 | 35 | 1 | 0 |
| Sonny Gray | Phi | sp | 35 | 2.54 | 12 | 7 | 0 | 33 | 33 | 0 | 0 | 208.2 | 138 | 63 | 59 | 61 | 223 | 27 | 14 |
| Chad Green | ChN | mr | 34 | 5.01 | 2 | 3 | 3 | 41 | 0 | 0 | 0 | 59.1 | 63 | 33 | 33 | 15 | 54 | 11 | 7 |
| Hunter Greene | Col | sp | 25 | 3.69 | 6 | 4 | 0 | 11 | 11 | 0 | 0 | 63.1 | 51 | 28 | 26 | 26 | 69 | 7 | 3 |
| Sean Guenther* | Bal | mr | 29 | 6.75 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1.1 | 3 | 1 | 1 | 1 | 0 | 0 | 0 |
| Luis Guerrero | | mr | 24 | 3.88 | 4 | 3 | 2 | 32 | 0 | 0 | 0 | 55.2 | 39 | 27 | 24 | 40 | 58 | 6 | 8 |
| Ryan Gusto | | sp | 26 | 6.12 | 0 | 1 | 0 | 14 | 1 | 0 | 0 | 25.0 | 32 | 18 | 17 | 14 | 18 | 4 | 4 |
| Josh Hader* | | cl | 31 | 3.76 | 3 | 2 | 19 | 40 | 0 | 0 | 0 | 40.2 | 35 | 21 | 17 | 23 | 63 | 8 | 1 |
| Skylar Hales | Atl | mr | 23 | 4.69 | 4 | 1 | 1 | 33 | 0 | 0 | 0 | 48.0 | 51 | 28 | 25 | 19 | 53 | 8 | 6 |
| DL Hall* | Bal | sp | 26 | 2.18 | 1 | 1 | 2 | 27 | 1 | 0 | 0 | 33.0 | 26 | 8 | 8 | 18 | 42 | 1 | 5 |
| Seth Halvorsen | Hou | mr | 25 | 2.35 | 1 | 5 | 15 | 49 | 0 | 0 | 0 | 57.1 | 42 | 21 | 15 | 27 | 53 | 6 | 0 |
| Ian Hamilton | Tex | mr | 30 | 2.93 | 8 | 6 | 2 | 33 | 20 | 0 | 0 | 119.2 | 104 | 43 | 39 | 55 | 134 | 7 | 17 |
| Emerson Hancock | Sea | sp | 26 | 4.37 | 1 | 0 | 0 | 4 | 4 | 0 | 0 | 22.2 | 22 | 12 | 11 | 15 | 13 | 0 | 3 |
| Brenan Hanifee | Det | mr | 27 | 3.85 | 13 | 15 | 0 | 36 | 36 | 1 | 1 | 215.0 | 190 | 97 | 92 | 62 | 171 | 26 | 16 |
| Landon Harper | Cin | mr | 24 | 1.23 | 0 | 0 | 0 | 6 | 1 | 0 | 0 | 14.2 | 12 | 2 | 2 | 1 | 6 | 0 | 2 |
| Thomas Harrington | Sea | sp | 23 | 3.81 | 7 | 9 | 0 | 26 | 26 | 0 | 0 | 130.0 | 117 | 65 | 55 | 51 | 104 | 20 | 5 |
| Hayden Harris* | Cle | mr | 26 | 81.00 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 0.2 | 6 | 6 | 6 | 2 | 2 | 1 | 0 |
| Kyle Harrison* | | sp | 23 | 3.55 | 8 | 8 | 0 | 35 | 27 | 0 | 0 | 152.0 | 137 | 67 | 60 | 53 | 140 | 16 | 8 |
| Kyle Hart* | Mil | sp | 32 | 3.73 | 10 | 8 | 1 | 34 | 29 | 0 | 0 | 176.1 | 165 | 78 | 73 | 48 | 157 | 18 | 12 |
| Grant Hartwig | NYN | mr | 27 | 8.44 | 0 | 0 | 3 | 10 | 0 | 0 | 0 | 10.2 | 9 | 10 | 10 | 9 | 14 | 1 | 1 |
| Hunter Harvey | Hou | mr | 30 | 1.25 | 3 | 1 | 2 | 14 | 0 | 0 | 0 | 21.2 | 17 | 4 | 3 | 8 | 19 | 1 | 1 |
| Brent Headrick* | NYA | sp | 27 | 5.84 | 1 | 2 | 1 | 15 | 4 | 0 | 0 | 37.0 | 43 | 26 | 24 | 10 | 40 | 8 | 2 |
| Andrew Heaney* | StL | sp | 34 | 5.70 | 5 | 13 | 0 | 27 | 23 | 0 | 0 | 121.2 | 119 | 80 | 77 | 53 | 126 | 23 | 6 |
| Ryan Helsley | Col | cl | 30 | 3.76 | 13 | 5 | 15 | 56 | 0 | 0 | 0 | 64.2 | 58 | 32 | 27 | 30 | 92 | 5 | 4 |
| Logan Henderson | SF | sp | 23 | 4.77 | 6 | 10 | 1 | 44 | 23 | 0 | 0 | 151.0 | 145 | 92 | 80 | 48 | 160 | 26 | 2 |
| Liam Hendriks | ChN | cl | 36 | 5.79 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.2 | 5 | 3 | 3 | 4 | 7 | 0 | 0 |
| Edgardo Henriquez | Atl | mr | 23 | 6.07 | 0 | 2 | 2 | 25 | 0 | 0 | 0 | 29.2 | 32 | 22 | 20 | 22 | 33 | 2 | 1 |
| Ronny Henriquez | Tex | mr | 25 | 5.20 | 3 | 2 | 3 | 51 | 0 | 0 | 0 | 53.2 | 63 | 39 | 31 | 25 | 46 | 10 | 7 |
| Cole Henry | Tor | sp | 25 | 4.72 | 0 | 3 | 1 | 26 | 0 | 0 | 0 | 26.2 | 20 | 15 | 14 | 19 | 25 | 2 | 3 |
| Tommy Henry* | LAA | sp | 27 | 5.30 | 0 | 0 | 1 | 15 | 0 | 0 | 0 | 18.2 | 22 | 15 | 11 | 11 | 15 | 3 | 2 |
| Carlos Hernandez | ChN | mr | 28 | 3.37 | 15 | 12 | 0 | 34 | 34 | 0 | 0 | 195.0 | 154 | 80 | 73 | 87 | 189 | 17 | 8 |
| Daysbel Hernandez | | mr | 28 | 4.80 | 3 | 4 | 2 | 44 | 0 | 0 | 0 | 50.2 | 51 | 30 | 27 | 32 | 56 | 6 | 4 |
| Tim Herrin* | | mr | 28 | 4.92 | 4 | 7 | 7 | 82 | 0 | 0 | 0 | 78.2 | 81 | 48 | 43 | 47 | 85 | 5 | 7 |
| Jordan Hicks | SF | mr | 28 | 4.58 | 2 | 6 | 15 | 40 | 7 | 0 | 0 | 88.1 | 91 | 53 | 45 | 58 | 87 | 11 | 11 |
| Jaden Hill | | mr | 25 | 6.64 | 1 | 4 | 3 | 13 | 4 | 0 | 0 | 40.2 | 42 | 31 | 30 | 22 | 37 | 9 | 2 |
| Sean Hjelle | SF | mr | 28 | 4.53 | 4 | 5 | 1 | 53 | 4 | 0 | 0 | 103.1 | 106 | 63 | 52 | 39 | 82 | 9 | 7 |
| Porter Hodge | Was | mr | 24 | 4.76 | 1 | 4 | 8 | 37 | 0 | 0 | 0 | 51.0 | 49 | 32 | 27 | 29 | 49 | 8 | 9 |
| Bryan Hoeing | | mr | 28 | 4.08 | 3 | 10 | 1 | 25 | 21 | 0 | 0 | 141.1 | 129 | 67 | 64 | 43 | 114 | 14 | 11 |
| Jeff Hoffman | Min | mr | 32 | 3.87 | 10 | 2 | 7 | 64 | 0 | 0 | 0 | 86.0 | 63 | 39 | 37 | 31 | 109 | 13 | 5 |
| Andrew Hoffmann | Hou | sp | 25 | 5.11 | 2 | 8 | 0 | 20 | 16 | 0 | 0 | 79.1 | 77 | 48 | 45 | 33 | 57 | 11 | 5 |
| Gunnar Hoglund | Sac | sp | 25 | 5.75 | 2 | 0 | 0 | 19 | 0 | 0 | 0 | 20.1 | 26 | 16 | 13 | 10 | 12 | 5 | 1 |
| Colin Holderman | Bal | mr | 29 | 5.31 | 5 | 6 | 1 | 47 | 7 | 0 | 0 | 78.0 | 80 | 59 | 46 | 43 | 73 | 12 | 6 |
| Grant Holman | KC | mr | 25 | 4.30 | 0 | 2 | 1 | 19 | 0 | 0 | 0 | 23.0 | 19 | 12 | 11 | 5 | 17 | 1 | 2 |
| Clay Holmes | Sac | sp | 32 | 5.31 | 9 | 17 | 0 | 33 | 33 | 0 | 0 | 173.0 | 194 | 106 | 102 | 56 | 132 | 15 | 15 |
| Grant Holmes | Mia | mr | 29 | 2.68 | 2 | 1 | 1 | 50 | 0 | 0 | 0 | 53.2 | 45 | 20 | 16 | 17 | 46 | 3 | 4 |
| Tyler Holton* | Cle | mr | 29 | 3.27 | 9 | 6 | 1 | 61 | 7 | 0 | 0 | 99.0 | 77 | 38 | 36 | 27 | 84 | 11 | 10 |
| Cade Horton | Tam | sp | 23 | 4.37 | 6 | 4 | 1 | 18 | 17 | 0 | 0 | 90.2 | 83 | 49 | 44 | 24 | 87 | 11 | 5 |
| Tanner Houck | LAN | sp | 29 | 4.73 | 4 | 8 | 0 | 16 | 16 | 0 | 0 | 85.2 | 74 | 49 | 45 | 34 | 69 | 9 | 4 |
| Adrian Houser | StL | sp | 32 | 5.82 | 0 | 3 | 2 | 31 | 0 | 0 | 0 | 38.2 | 39 | 28 | 25 | 21 | 25 | 7 | 1 |
| Bryan Hudson* | Col | mr | 28 | 3.23 | 2 | 1 | 3 | 71 | 0 | 0 | 0 | 83.2 | 72 | 34 | 30 | 32 | 90 | 6 | 8 |
| Brandon Hughes* | NYN | mr | 29 | 3.25 | 3 | 1 | 0 | 5 | 5 | 0 | 0 | 27.2 | 17 | 10 | 10 | 11 | 37 | 3 | 1 |
| K.C. Hunt | Bos | sp | 24 | 4.20 | 4 | 8 | 0 | 47 | 16 | 0 | 0 | 120.0 | 94 | 61 | 56 | 56 | 119 | 9 | 3 |
| Brant Hurter* | ChN | sp | 26 | 4.32 | 17 | 9 | 0 | 33 | 33 | 1 | 0 | 187.2 | 191 | 92 | 90 | 53 | 135 | 20 | 14 |
| Raisel Iglesias | | cl | 35 | 3.92 | 10 | 6 | 8 | 68 | 0 | 0 | 0 | 87.1 | 69 | 43 | 38 | 20 | 99 | 14 | 4 |
| Shota Imanaga* | Col | sp | 31 | 4.23 | 9 | 6 | 0 | 26 | 26 | 0 | 0 | 151.0 | 159 | 78 | 71 | 36 | 132 | 17 | 13 |
| Jairo Iriarte | Col | sp | 23 | 3.73 | 2 | 1 | 1 | 18 | 2 | 0 | 0 | 31.1 | 26 | 13 | 13 | 11 | 24 | 3 | 4 |
| Cole Irvin* | | sp | 31 | 3.73 | 4 | 5 | 3 | 38 | 6 | 0 | 0 | 82.0 | 72 | 44 | 34 | 26 | 59 | 7 | 5 |
| Jake Irvin | | sp | 28 | 5.16 | 0 | 7 | 0 | 13 | 13 | 0 | 0 | 75.0 | 82 | 47 | 43 | 28 | 53 | 10 | 7 |
| Luke Jackson | Bal | mr | 33 | 5.31 | 3 | 4 | 2 | 58 | 0 | 0 | 0 | 79.2 | 70 | 51 | 47 | 42 | 88 | 11 | 5 |
| Alek Jacob | Pit | mr | 27 | 3.30 | 2 | 4 | 6 | 60 | 0 | 0 | 0 | 79.0 | 69 | 32 | 29 | 35 | 70 | 6 | 9 |
| Drey Jameson | Was | sp | 27 | 3.81 | 15 | 10 | 0 | 32 | 32 | 1 | 1 | 191.1 | 168 | 84 | 81 | 55 | 168 | 21 | 14 |
| Kenley Jansen | Tam | cl | 37 | 3.22 | 3 | 0 | 2 | 75 | 0 | 0 | 0 | 78.1 | 51 | 29 | 28 | 33 | 92 | 4 | 2 |
| Cristian Javier | Min | sp | 28 | 4.22 | 3 | 0 | 1 | 16 | 0 | 0 | 0 | 21.1 | 21 | 10 | 10 | 9 | 17 | 2 | 1 |
| Griffin Jax | Mia | mr | 30 | 3.00 | 12 | 6 | 24 | 64 | 0 | 0 | 0 | 69.0 | 59 | 29 | 23 | 20 | 75 | 2 | 4 |
| Jackson Jobe | SF | sp | 22 | 4.94 | 1 | 6 | 1 | 16 | 13 | 0 | 0 | 78.1 | 79 | 48 | 43 | 23 | 70 | 13 | 3 |
| Pierce Johnson | Mil | mr | 34 | 4.72 | 4 | 6 | 3 | 65 | 0 | 0 | 0 | 76.1 | 65 | 40 | 40 | 35 | 87 | 10 | 10 |
| Seth Johnson | StL | sp | 26 | 5.46 | 2 | 3 | 4 | 25 | 0 | 0 | 0 | 29.2 | 26 | 25 | 18 | 22 | 20 | 4 | 1 |
| Ben Joyce | Sac | mr | 24 | 7.11 | 1 | 1 | 0 | 5 | 0 | 0 | 0 | 6.1 | 5 | 7 | 5 | 3 | 10 | 0 | 0 |
| Jakob Junis | Det | mr | 32 | 3.32 | 0 | 2 | 3 | 29 | 0 | 0 | 0 | 40.2 | 38 | 20 | 15 | 10 | 36 | 3 | 4 |
| Janson Junk | Tex | sp | 29 | 4.62 | 1 | 4 | 3 | 26 | 0 | 0 | 0 | 39.0 | 35 | 25 | 20 | 20 | 25 | 7 | 7 |
| Tommy Kahnle | | mr | 35 | 3.99 | 5 | 2 | 0 | 31 | 0 | 0 | 0 | 29.1 | 25 | 18 | 13 | 18 | 34 | 3 | 2 |
| James Karinchak | Min | mr | 29 | 4.07 | 2 | 1 | 0 | 21 | 0 | 0 | 0 | 24.1 | 22 | 16 | 11 | 13 | 22 | 1 | 1 |
| Mitch Keller | KC | sp | 29 | 3.13 | 12 | 9 | 0 | 34 | 34 | 0 | 0 | 204.1 | 168 | 84 | 71 | 62 | 174 | 18 | 15 |
| Kevin Kelly | | mr | 27 | 2.92 | 5 | 3 | 12 | 47 | 0 | 0 | 0 | 61.2 | 45 | 22 | 20 | 16 | 55 | 7 | 6 |
| Merrill Kelly | Det | sp | 36 | 5.12 | 10 | 8 | 0 | 22 | 20 | 0 | 0 | 121.1 | 121 | 69 | 69 | 49 | 98 | 26 | 8 |
| Zak Kent | KC | sp | 27 | 3.94 | 5 | 2 | 4 | 70 | 0 | 0 | 0 | 77.2 | 76 | 40 | 34 | 23 | 76 | 13 | 5 |
| Orion Kerkering | Bos | mr | 24 | 1.44 | 7 | 3 | 2 | 52 | 0 | 0 | 0 | 68.2 | 43 | 14 | 11 | 22 | 68 | 0 | 7 |
| Clayton Kershaw* | LAA | sp | 37 | 3.62 | 7 | 7 | 0 | 25 | 25 | 0 | 0 | 129.1 | 113 | 59 | 52 | 31 | 116 | 14 | 6 |
| Yusei Kikuchi* | NYN | sp | 34 | 3.37 | 14 | 9 | 0 | 32 | 32 | 1 | 1 | 187.0 | 156 | 78 | 70 | 49 | 232 | 18 | 10 |
| Craig Kimbrel | Cle | cl | 37 | 5.03 | 5 | 2 | 2 | 29 | 0 | 0 | 0 | 34.0 | 26 | 20 | 19 | 16 | 47 | 2 | 3 |
| Bryan King* | Tam | mr | 28 | 2.23 | 4 | 2 | 4 | 63 | 0 | 0 | 0 | 68.2 | 53 | 23 | 17 | 32 | 63 | 4 | 9 |
| John King* | KC | mr | 30 | 3.71 | 7 | 10 | 28 | 73 | 0 | 0 | 0 | 80.0 | 75 | 42 | 33 | 34 | 53 | 6 | 11 |
| Michael King | Tam | sp | 30 | 2.40 | 10 | 3 | 0 | 16 | 16 | 0 | 0 | 97.2 | 58 | 27 | 26 | 28 | 113 | 8 | 2 |
| George Kirby | Sea | sp | 27 | 3.86 | 4 | 9 | 0 | 23 | 23 | 0 | 0 | 130.2 | 121 | 59 | 56 | 32 | 121 | 11 | 8 |
| Andrew Kittredge | ChN | mr | 35 | 3.54 | 4 | 5 | 2 | 45 | 1 | 0 | 0 | 61.0 | 61 | 30 | 24 | 15 | 48 | 7 | 4 |
| George Klassen | Bos | sp | 23 | 5.40 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 5.0 | 6 | 4 | 3 | 3 | 3 | 1 | 1 |
| Jack Kochanowicz | StL | sp | 24 | 5.10 | 2 | 12 | 0 | 17 | 17 | 0 | 0 | 97.0 | 107 | 62 | 55 | 27 | 49 | 8 | 8 |
| Jared Koenig* | Tam | mr | 31 | 5.29 | 1 | 3 | 2 | 50 | 0 | 0 | 0 | 51.0 | 67 | 33 | 30 | 29 | 46 | 3 | 3 |
| Stephen Kolek | | mr | 28 | 4.28 | 2 | 4 | 0 | 42 | 0 | 0 | 0 | 54.2 | 58 | 27 | 26 | 21 | 46 | 3 | 4 |
| Michael Kopech | SF | mr | 29 | 0.00 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 3.0 | 1 | 0 | 0 | 0 | 4 | 0 | 0 |
| Dean Kremer | Det | sp | 29 | 4.74 | 11 | 7 | 0 | 32 | 32 | 0 | 0 | 157.2 | 151 | 90 | 83 | 67 | 126 | 19 | 13 |
| Ben Kudrna | | sp | 22 | 12.00 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 9.0 | 13 | 13 | 12 | 4 | 8 | 3 | 0 |
| Alex Lange | LAN | mr | 29 | 3.95 | 3 | 6 | 2 | 63 | 5 | 0 | 0 | 82.0 | 70 | 37 | 36 | 60 | 80 | 9 | 7 |
| Sauryn Lao | Sac | mr | 25 | 4.66 | 4 | 4 | 5 | 57 | 0 | 0 | 0 | 75.1 | 76 | 45 | 39 | 31 | 67 | 14 | 9 |
| Andry Lara | LAN | sp | 22 | 3.75 | 8 | 9 | 0 | 31 | 31 | 0 | 0 | 156.0 | 166 | 78 | 65 | 75 | 107 | 11 | 6 |
| Jhancarlos Lara | StL | sp | 22 | 4.50 | 0 | 1 | 0 | 19 | 0 | 0 | 0 | 16.0 | 18 | 9 | 8 | 14 | 15 | 2 | 4 |
| Jake Latz* | NYA | mr | 29 | 3.18 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 5.2 | 2 | 2 | 2 | 2 | 5 | 1 | 0 |
| Eric Lauer* | Tex | sp | 30 | 3.65 | 3 | 1 | 1 | 16 | 5 | 0 | 0 | 44.1 | 49 | 20 | 18 | 13 | 40 | 2 | 1 |
| Max Lazar | Phi | mr | 26 | 3.48 | 5 | 3 | 1 | 46 | 1 | 0 | 0 | 75.0 | 64 | 29 | 29 | 24 | 61 | 9 | 6 |
| Kyle Leahy | ChN | mr | 28 | 4.70 | 0 | 1 | 1 | 11 | 0 | 0 | 0 | 15.1 | 19 | 9 | 8 | 8 | 11 | 2 | 2 |
| Jordan Leasure | Sac | mr | 26 | 6.00 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 6.0 | 4 | 4 | 4 | 6 | 7 | 2 | 0 |
| Jose Leclerc | Pit | mr | 31 | 4.84 | 2 | 1 | 2 | 15 | 0 | 0 | 0 | 22.1 | 11 | 13 | 12 | 13 | 27 | 0 | 1 |
| Chase Lee | | mr | 26 | 5.44 | 3 | 1 | 2 | 46 | 0 | 0 | 0 | 51.1 | 61 | 33 | 31 | 21 | 57 | 10 | 1 |
| Dylan Lee* | Det | mr | 30 | 4.56 | 4 | 9 | 13 | 69 | 0 | 0 | 0 | 77.0 | 81 | 55 | 39 | 24 | 101 | 12 | 2 |
| Jack Leiter | SF | sp | 25 | 3.52 | 2 | 2 | 0 | 23 | 0 | 0 | 0 | 30.2 | 28 | 14 | 12 | 14 | 33 | 4 | 4 |
| Mark Jr. Leiter | | mr | 34 | 4.85 | 3 | 2 | 11 | 36 | 0 | 0 | 0 | 42.2 | 31 | 26 | 23 | 20 | 54 | 9 | 2 |
| Matthew Liberatore* | Cin | mr | 25 | 6.00 | 1 | 6 | 0 | 17 | 13 | 0 | 0 | 72.0 | 81 | 51 | 48 | 31 | 51 | 11 | 9 |
| Zack Littell | | sp | 29 | 5.52 | 6 | 6 | 1 | 31 | 15 | 0 | 0 | 106.0 | 122 | 72 | 65 | 24 | 90 | 15 | 10 |
| Brendon Little* | LAN | mr | 28 | 5.15 | 5 | 7 | 4 | 58 | 0 | 0 | 0 | 78.2 | 72 | 50 | 45 | 53 | 66 | 5 | 6 |
| Luke Little* | Col | mr | 24 | 2.97 | 6 | 5 | 1 | 56 | 0 | 0 | 0 | 60.2 | 51 | 27 | 20 | 27 | 66 | 6 | 7 |
| Ben Lively | Col | sp | 33 | 3.60 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 5.0 | 5 | 2 | 2 | 2 | 2 | 2 | 1 |
| Jonathan Loaisiga | Ari | mr | 30 | 3.38 | 0 | 4 | 6 | 32 | 0 | 0 | 0 | 40.0 | 42 | 25 | 15 | 12 | 39 | 1 | 3 |
| Ryan Lobus | ChA | mr | 24 | 5.01 | 3 | 2 | 0 | 10 | 4 | 0 | 0 | 41.1 | 37 | 26 | 23 | 15 | 38 | 10 | 1 |
| Nick Lodolo* | | sp | 27 | 4.78 | 8 | 7 | 0 | 29 | 24 | 1 | 0 | 137.1 | 119 | 84 | 73 | 60 | 152 | 19 | 8 |
| Jacob Lopez* | Tex | sp | 27 | 3.60 | 4 | 1 | 1 | 14 | 0 | 0 | 0 | 20.0 | 15 | 10 | 8 | 7 | 20 | 4 | 1 |
| Pablo Lopez | Tex | sp | 29 | 2.90 | 5 | 4 | 0 | 14 | 14 | 1 | 1 | 87.0 | 67 | 33 | 28 | 25 | 105 | 9 | 4 |
| Brad Lord | Sac | sp | 25 | 3.71 | 1 | 0 | 1 | 23 | 0 | 0 | 0 | 34.0 | 30 | 16 | 14 | 14 | 25 | 1 | 5 |
| Michael Lorenzen | | sp | 33 | 4.76 | 3 | 7 | 0 | 24 | 20 | 1 | 0 | 121.0 | 115 | 66 | 64 | 65 | 83 | 21 | 9 |
| Richard Lovelady* | ChN | mr | 29 | 3.07 | 9 | 5 | 0 | 28 | 26 | 0 | 0 | 149.2 | 132 | 54 | 51 | 32 | 131 | 7 | 5 |
| Seth Lugo | NYN | sp | 35 | 4.06 | 6 | 10 | 0 | 30 | 30 | 0 | 0 | 173.0 | 150 | 79 | 78 | 51 | 163 | 22 | 9 |
| Jesus Luzardo* | Tex | sp | 27 | 2.76 | 6 | 3 | 3 | 46 | 10 | 0 | 0 | 98.0 | 80 | 35 | 30 | 39 | 106 | 7 | 8 |
| Daniel Lynch* | Phi | sp | 28 | 3.38 | 1 | 1 | 0 | 3 | 1 | 0 | 0 | 8.0 | 4 | 3 | 3 | 4 | 5 | 0 | 1 |
| Tyler Mahle | Ari | sp | 30 | 2.52 | 5 | 3 | 0 | 11 | 11 | 0 | 0 | 71.1 | 54 | 23 | 20 | 25 | 68 | 4 | 4 |
| Alek Manoah | Sea | sp | 27 | 2.16 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 16.2 | 16 | 7 | 4 | 7 | 13 | 1 | 3 |
| Joe Mantiply* | Col | mr | 34 | 2.58 | 1 | 1 | 4 | 39 | 0 | 0 | 0 | 45.1 | 30 | 14 | 13 | 12 | 45 | 4 | 6 |
| Ron Marinaccio | ChA | mr | 29 | 4.48 | 4 | 8 | 12 | 78 | 0 | 0 | 0 | 90.1 | 74 | 51 | 45 | 64 | 96 | 10 | 5 |
| German Marquez | | sp | 30 | 2.87 | 6 | 4 | 0 | 21 | 16 | 0 | 0 | 97.1 | 84 | 33 | 31 | 32 | 79 | 5 | 12 |
| Yunior Marte | StL | sp | 21 | 6.65 | 2 | 1 | 2 | 24 | 0 | 0 | 0 | 21.2 | 23 | 16 | 16 | 14 | 14 | 5 | 1 |
| Chris Martin | ChN | mr | 39 | 2.59 | 1 | 4 | 6 | 44 | 0 | 0 | 0 | 55.2 | 52 | 19 | 16 | 8 | 61 | 2 | 2 |
| Davis Martin | SD | sp | 28 | 1.86 | 1 | 0 | 1 | 9 | 0 | 0 | 0 | 9.2 | 7 | 3 | 2 | 4 | 10 | 0 | 0 |
| Riley Martin* | NYA | mr | 27 | 4.70 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 15.1 | 15 | 8 | 8 | 7 | 14 | 1 | 0 |
| Justin Martinez | Tex | mr | 23 | 3.60 | 3 | 5 | 4 | 21 | 0 | 0 | 0 | 25.0 | 20 | 12 | 10 | 11 | 35 | 0 | 1 |
| Nick Martinez | Mil | mr | 34 | 3.80 | 8 | 10 | 0 | 32 | 32 | 1 | 0 | 187.0 | 178 | 88 | 79 | 47 | 175 | 11 | 12 |
| Quinn Mathews* | StL | sp | 24 | 5.11 | 4 | 14 | 0 | 27 | 25 | 0 | 0 | 132.0 | 123 | 84 | 75 | 63 | 133 | 9 | 5 |
| Phil Maton | NYN | mr | 32 | 2.40 | 2 | 3 | 3 | 38 | 0 | 0 | 0 | 48.2 | 39 | 15 | 13 | 12 | 51 | 3 | 1 |
| Yuki Matsui* | NYN | mr | 29 | 7.50 | 2 | 1 | 1 | 26 | 1 | 0 | 0 | 24.0 | 28 | 22 | 20 | 22 | 26 | 7 | 1 |
| Zebby Matthews | Was | sp | 25 | 1.59 | 2 | 1 | 5 | 29 | 0 | 0 | 0 | 28.1 | 23 | 6 | 5 | 3 | 28 | 3 | 1 |
| Isaac Mattson | Ari | mr | 29 | 5.00 | 0 | 2 | 1 | 8 | 0 | 0 | 0 | 9.0 | 12 | 6 | 5 | 7 | 8 | 1 | 3 |
| Steven Matz* | LAA | sp | 34 | 3.03 | 14 | 5 | 0 | 36 | 23 | 0 | 0 | 148.1 | 116 | 56 | 50 | 56 | 129 | 12 | 13 |
| Zach Maxwell | | mr | 24 | 5.98 | 5 | 2 | 4 | 37 | 0 | 0 | 0 | 46.2 | 38 | 34 | 31 | 34 | 49 | 5 | 3 |
| Dustin May | Was | sp | 27 | 3.04 | 12 | 10 | 0 | 32 | 32 | 2 | 1 | 201.1 | 131 | 69 | 68 | 79 | 195 | 17 | 6 |
| Adam Mazur | Tam | sp | 24 | 2.04 | 3 | 2 | 0 | 15 | 4 | 0 | 0 | 39.2 | 28 | 16 | 9 | 9 | 21 | 2 | 3 |
| Lance McCullers | Tex | sp | 31 | 3.76 | 5 | 2 | 0 | 14 | 14 | 0 | 0 | 76.2 | 66 | 40 | 32 | 40 | 66 | 6 | 4 |
| Chayce McDermott | LAN | sp | 26 | 4.69 | 10 | 14 | 0 | 32 | 32 | 0 | 0 | 174.2 | 146 | 97 | 91 | 91 | 178 | 31 | 3 |
| Griff McGarry | Bal | mr | 26 | 3.03 | 4 | 0 | 1 | 25 | 0 | 0 | 0 | 29.2 | 22 | 12 | 10 | 26 | 20 | 3 | 3 |
| Easton McGee | | sp | 27 | 6.57 | 1 | 2 | 0 | 6 | 4 | 0 | 0 | 24.2 | 34 | 19 | 18 | 6 | 21 | 4 | 2 |
| Michael McGreevy | ChA | sp | 24 | 5.32 | 7 | 15 | 0 | 33 | 32 | 0 | 0 | 176.0 | 207 | 112 | 104 | 63 | 145 | 24 | 18 |
| Nolan McLean | Atl | dh | 23 | 5.00 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 9.0 | 10 | 5 | 5 | 7 | 7 | 0 | 1 |
| Nick Mears | Phi | mr | 28 | 4.66 | 9 | 4 | 4 | 59 | 0 | 0 | 0 | 67.2 | 58 | 36 | 35 | 39 | 87 | 11 | 5 |
| Trevor Megill | | cl | 31 | 3.72 | 3 | 4 | 6 | 40 | 0 | 0 | 0 | 46.0 | 38 | 21 | 19 | 22 | 55 | 2 | 3 |
| Tylor Megill | NYN | sp | 29 | 6.35 | 0 | 2 | 0 | 7 | 6 | 0 | 0 | 28.1 | 30 | 20 | 20 | 17 | 27 | 8 | 3 |
| Cristian Mena | SD | sp | 22 | 5.35 | 4 | 4 | 0 | 14 | 14 | 0 | 0 | 75.2 | 75 | 53 | 45 | 45 | 61 | 9 | 2 |
| Julian Merryweather | | mr | 33 | 4.60 | 1 | 4 | 5 | 39 | 0 | 0 | 0 | 43.0 | 34 | 23 | 22 | 24 | 47 | 3 | 0 |
| Luis Mey | Phi | mr | 24 | 10.13 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.2 | 6 | 3 | 3 | 2 | 2 | 2 | 1 |
| Max Meyer | ChA | sp | 26 | 4.27 | 5 | 12 | 0 | 33 | 30 | 0 | 0 | 160.1 | 143 | 81 | 76 | 67 | 143 | 14 | 14 |
| Miles Mikolas | | sp | 36 | 7.07 | 1 | 10 | 0 | 17 | 17 | 0 | 0 | 91.2 | 125 | 75 | 72 | 24 | 66 | 21 | 6 |
| Bobby Miller | Bal | sp | 26 | 4.57 | 4 | 5 | 0 | 22 | 21 | 0 | 0 | 108.1 | 91 | 63 | 55 | 44 | 97 | 10 | 6 |
| Bryce Miller | | sp | 26 | 4.84 | 3 | 9 | 0 | 17 | 17 | 0 | 0 | 96.2 | 98 | 57 | 52 | 22 | 93 | 13 | 6 |
| Erik Miller* | Tor | mr | 27 | 5.94 | 0 | 6 | 0 | 22 | 11 | 0 | 0 | 63.2 | 72 | 50 | 42 | 39 | 72 | 8 | 1 |
| Jacob Miller | StL | sp | 21 | 5.01 | 1 | 2 | 0 | 5 | 4 | 0 | 0 | 23.1 | 32 | 15 | 13 | 12 | 16 | 3 | 1 |
| Mason Miller | Bos | cl | 26 | 2.61 | 7 | 6 | 23 | 67 | 0 | 0 | 0 | 86.1 | 72 | 30 | 25 | 34 | 109 | 7 | 9 |
| Shelby Miller | | mr | 34 | 3.50 | 3 | 2 | 2 | 30 | 4 | 0 | 0 | 54.0 | 40 | 23 | 21 | 21 | 49 | 9 | 2 |
| Tyson Miller | Mil | mr | 29 | 4.72 | 2 | 3 | 3 | 31 | 0 | 0 | 0 | 40.0 | 33 | 22 | 21 | 16 | 30 | 5 | 5 |
| Hoby Milner* | | mr | 34 | 4.48 | 5 | 5 | 4 | 66 | 0 | 0 | 0 | 62.1 | 62 | 32 | 31 | 13 | 47 | 5 | 4 |
| Camden Minacci | Cin | mr | 23 | 8.00 | 1 | 0 | 0 | 9 | 0 | 0 | 0 | 9.0 | 10 | 9 | 8 | 3 | 11 | 2 | 0 |
| A.J. Minter* | Was | mr | 31 | 3.24 | 1 | 2 | 6 | 29 | 0 | 0 | 0 | 33.1 | 26 | 16 | 12 | 23 | 48 | 2 | 5 |
| Andrew Misiaszek* | | mr | 27 | 3.51 | 0 | 2 | 2 | 17 | 1 | 0 | 0 | 25.2 | 25 | 12 | 10 | 18 | 22 | 5 | 4 |
| Jacob Misiorowski | Tex | sp | 23 | 7.20 | 0 | 0 | 2 | 19 | 1 | 0 | 0 | 20.0 | 18 | 16 | 16 | 20 | 21 | 4 | 0 |
| Casey Mize | KC | sp | 28 | 4.29 | 1 | 3 | 0 | 15 | 15 | 0 | 0 | 71.1 | 66 | 38 | 34 | 33 | 55 | 3 | 6 |
| Carmen Mlodzinski | KC | mr | 26 | 4.43 | 5 | 4 | 3 | 88 | 0 | 0 | 0 | 89.1 | 91 | 53 | 44 | 31 | 76 | 9 | 6 |
| Keider Montero | | sp | 24 | 8.60 | 1 | 4 | 1 | 20 | 5 | 0 | 0 | 37.2 | 49 | 37 | 36 | 18 | 26 | 7 | 2 |
| Mason Montgomery* | | sp | 25 | 3.75 | 7 | 3 | 2 | 38 | 9 | 0 | 0 | 74.1 | 65 | 37 | 31 | 28 | 68 | 8 | 2 |
| Michael Morales | StL | sp | 22 | 7.71 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 2.1 | 3 | 2 | 2 | 1 | 2 | 1 | 0 |
| Adrian Morejon* | Cle | mr | 26 | 4.11 | 3 | 1 | 2 | 69 | 0 | 0 | 0 | 70.0 | 67 | 35 | 32 | 34 | 75 | 4 | 6 |
| Dauri Moreta | Mil | mr | 29 | 4.50 | 0 | 0 | 0 | 19 | 0 | 0 | 0 | 20.0 | 24 | 10 | 10 | 9 | 14 | 4 | 0 |
| David Morgan | Col | mr | 25 | 8.53 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 6.1 | 8 | 6 | 6 | 1 | 6 | 0 | 0 |
| Eli Morgan | Det | mr | 29 | 7.24 | 0 | 5 | 0 | 5 | 5 | 0 | 0 | 27.1 | 31 | 22 | 22 | 9 | 25 | 5 | 1 |
| Andrew Morris | Cin | sp | 23 | 4.59 | 1 | 1 | 0 | 6 | 5 | 0 | 0 | 33.1 | 31 | 18 | 17 | 3 | 20 | 6 | 1 |
| Charlie Morton | | sp | 41 | 4.09 | 10 | 12 | 0 | 35 | 33 | 0 | 0 | 185.0 | 138 | 96 | 84 | 87 | 206 | 17 | 13 |
| Andres Munoz | Sea | cl | 26 | 3.25 | 7 | 5 | 0 | 75 | 0 | 0 | 0 | 91.1 | 68 | 37 | 33 | 31 | 120 | 9 | 5 |
| Penn Murfee | Pit | mr | 31 | 4.33 | 2 | 3 | 1 | 16 | 4 | 0 | 0 | 35.1 | 30 | 21 | 17 | 14 | 22 | 4 | 3 |
| Tobias Myers | Min | sp | 26 | 3.75 | 6 | 6 | 0 | 23 | 23 | 0 | 0 | 129.2 | 122 | 63 | 54 | 37 | 119 | 16 | 11 |
| Jack Neely | Hou | mr | 25 | 2.69 | 2 | 1 | 3 | 42 | 0 | 0 | 0 | 63.2 | 52 | 23 | 19 | 22 | 61 | 3 | 3 |
| Kyle Nelson* | Atl | mr | 28 | 3.55 | 2 | 1 | 0 | 42 | 0 | 0 | 0 | 38.0 | 28 | 15 | 15 | 13 | 33 | 5 | 3 |
| Ryne Nelson | Cin | sp | 27 | 5.04 | 7 | 14 | 0 | 34 | 30 | 0 | 0 | 182.0 | 204 | 112 | 102 | 60 | 135 | 32 | 18 |
| Kyle Nicolas | Atl | mr | 26 | 5.42 | 5 | 5 | 3 | 76 | 0 | 0 | 0 | 104.2 | 107 | 68 | 63 | 47 | 111 | 12 | 8 |
| Doug Nikhazy* | Was | sp | 25 | 1.74 | 0 | 0 | 2 | 16 | 0 | 0 | 0 | 20.2 | 12 | 4 | 4 | 8 | 25 | 3 | 2 |
| Aaron Nola | Min | sp | 32 | 2.84 | 5 | 3 | 0 | 15 | 15 | 2 | 2 | 101.1 | 85 | 36 | 32 | 23 | 93 | 10 | 6 |
| Dedniel Nunez | Tex | mr | 29 | 5.45 | 8 | 5 | 0 | 53 | 0 | 0 | 0 | 67.2 | 69 | 46 | 41 | 29 | 78 | 8 | 4 |
| Juan Nunez | Phi | sp | 29 | 6.75 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 2 | 1 | 1 | 0 | 2 | 1 | 0 |
| Riley O'Brien | ChA | mr | 30 | 4.76 | 4 | 4 | 2 | 64 | 2 | 0 | 0 | 85.0 | 81 | 51 | 45 | 47 | 84 | 12 | 12 |
| Bailey Ober | Phi | sp | 29 | 3.46 | 11 | 8 | 0 | 29 | 29 | 1 | 1 | 169.0 | 137 | 69 | 65 | 40 | 173 | 23 | 7 |
| Shohei Ohtani | Tex | dh | 30 | 4.45 | 8 | 3 | 0 | 16 | 16 | 1 | 0 | 95.0 | 72 | 57 | 47 | 42 | 103 | 22 | 3 |
| Steven Okert* | Bos | mr | 33 | 3.74 | 1 | 3 | 4 | 43 | 0 | 0 | 0 | 43.1 | 32 | 20 | 18 | 21 | 43 | 4 | 2 |
| Reese Olson | KC | sp | 25 | 3.04 | 8 | 4 | 0 | 19 | 19 | 0 | 0 | 100.2 | 74 | 40 | 34 | 34 | 101 | 5 | 8 |
| Oliver Ortega | Bal | mr | 28 | 3.81 | 7 | 4 | 3 | 77 | 0 | 0 | 0 | 115.2 | 104 | 54 | 49 | 45 | 124 | 8 | 6 |
| Luis L. Ortiz | SD | sp | 26 | 3.62 | 5 | 6 | 0 | 17 | 17 | 0 | 0 | 87.0 | 72 | 38 | 35 | 35 | 84 | 9 | 10 |
| Eric Orze | | mr | 27 | 4.50 | 0 | 0 | 1 | 21 | 0 | 0 | 0 | 32.0 | 37 | 17 | 16 | 11 | 26 | 2 | 3 |
| Johan Oviedo | Cle | sp | 27 | 2.31 | 3 | 2 | 0 | 11 | 5 | 0 | 0 | 35.0 | 27 | 11 | 9 | 14 | 34 | 1 | 3 |
| Chris Paddack | LAA | sp | 29 | 2.93 | 17 | 5 | 0 | 32 | 32 | 1 | 0 | 184.0 | 155 | 60 | 60 | 43 | 175 | 16 | 9 |
| Emilio Pagan | ChA | mr | 34 | 5.11 | 7 | 4 | 2 | 76 | 0 | 0 | 0 | 75.2 | 75 | 45 | 43 | 23 | 72 | 12 | 2 |
| Andrew Painter | Atl | sp | 22 | 3.49 | 1 | 2 | 0 | 9 | 9 | 0 | 0 | 49.0 | 45 | 22 | 19 | 17 | 52 | 6 | 1 |
| Daniel Palencia | Sea | mr | 25 | 4.85 | 6 | 4 | 2 | 38 | 13 | 0 | 0 | 102.0 | 84 | 57 | 55 | 60 | 112 | 13 | 6 |
| Andre Pallante | Min | sp | 26 | 5.05 | 5 | 6 | 0 | 30 | 15 | 0 | 0 | 107.0 | 108 | 64 | 60 | 47 | 70 | 10 | 7 |
| Peyton Pallette | SD | mr | 24 | 1.59 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 5.2 | 4 | 1 | 1 | 0 | 10 | 0 | 0 |
| Mitchell Parker* | Atl | sp | 25 | 4.67 | 6 | 9 | 1 | 48 | 15 | 0 | 0 | 113.2 | 114 | 66 | 59 | 44 | 124 | 13 | 10 |
| Joel Payamps | | mr | 31 | 2.24 | 10 | 2 | 3 | 71 | 0 | 0 | 0 | 84.1 | 63 | 25 | 21 | 24 | 85 | 7 | 3 |
| Nate Pearson | Hou | mr | 28 | 6.29 | 1 | 3 | 0 | 12 | 6 | 0 | 0 | 34.1 | 28 | 27 | 24 | 20 | 44 | 8 | 0 |
| Ethan Pecko | Hou | sp | 22 | 5.10 | 5 | 4 | 0 | 29 | 5 | 0 | 0 | 65.1 | 71 | 39 | 37 | 27 | 51 | 3 | 5 |
| Elvis Peguero | Det | mr | 28 | 4.12 | 6 | 4 | 1 | 74 | 0 | 0 | 0 | 83.0 | 92 | 44 | 38 | 35 | 62 | 8 | 6 |
| Walter Pennington* | NYA | mr | 27 | 2.60 | 1 | 1 | 1 | 10 | 2 | 0 | 0 | 27.2 | 20 | 8 | 8 | 13 | 25 | 0 | 4 |
| Ryan Pepiot | KC | sp | 27 | 3.89 | 8 | 7 | 0 | 31 | 31 | 0 | 0 | 159.2 | 142 | 76 | 69 | 62 | 172 | 17 | 5 |
| Freddy Peralta | Mia | sp | 29 | 3.93 | 10 | 7 | 0 | 36 | 36 | 0 | 0 | 187.2 | 154 | 83 | 82 | 88 | 201 | 21 | 9 |
| Wandy Peralta* | SD | mr | 33 | 2.66 | 3 | 0 | 2 | 31 | 0 | 0 | 0 | 23.2 | 19 | 8 | 7 | 15 | 22 | 3 | 1 |
| Angel Perdomo* | Mia | mr | 31 | 2.23 | 3 | 3 | 4 | 38 | 0 | 0 | 0 | 44.1 | 25 | 12 | 11 | 22 | 63 | 6 | 4 |
| Cionel Perez* | | mr | 29 | 5.08 | 2 | 7 | 0 | 37 | 0 | 0 | 0 | 39.0 | 38 | 26 | 22 | 18 | 30 | 5 | 3 |
| Eury Perez | Bal | sp | 22 | 4.44 | 6 | 6 | 0 | 19 | 19 | 0 | 0 | 105.1 | 95 | 57 | 52 | 48 | 102 | 18 | 3 |
| Martin Perez* | LAN | sp | 34 | 2.49 | 1 | 0 | 0 | 4 | 4 | 0 | 0 | 25.1 | 22 | 8 | 7 | 8 | 18 | 1 | 2 |
| Jack Perkins | ChA | sp | 25 | 4.99 | 1 | 3 | 0 | 22 | 5 | 0 | 0 | 48.2 | 44 | 29 | 27 | 19 | 39 | 10 | 3 |
| David Peterson* | Sac | sp | 29 | 4.27 | 9 | 8 | 1 | 42 | 17 | 0 | 0 | 128.2 | 116 | 66 | 61 | 50 | 113 | 13 | 17 |
| Chase Petty | ChA | sp | 22 | 6.18 | 0 | 0 | 1 | 23 | 0 | 0 | 0 | 43.2 | 50 | 32 | 30 | 21 | 39 | 9 | 2 |
| Brandon Pfaadt | Col | sp | 26 | 4.98 | 12 | 7 | 0 | 31 | 31 | 0 | 0 | 177.0 | 170 | 101 | 98 | 57 | 187 | 35 | 10 |
| Evan Phillips | Mil | cl | 30 | 4.32 | 1 | 1 | 5 | 7 | 0 | 0 | 0 | 8.1 | 8 | 4 | 4 | 4 | 8 | 0 | 1 |
| Tyler Phillips | Cle | sp | 27 | 10.80 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 3.1 | 5 | 4 | 4 | 2 | 2 | 0 | 0 |
| Nick Pivetta | Cle | sp | 32 | 5.34 | 7 | 7 | 0 | 36 | 20 | 0 | 0 | 119.2 | 137 | 74 | 71 | 45 | 144 | 15 | 8 |
| Drew Pomeranz* | Was | mr | 36 | 4.09 | 6 | 3 | 1 | 52 | 3 | 0 | 0 | 61.2 | 53 | 30 | 28 | 33 | 61 | 7 | 7 |
| Cody Poteet | NYN | sp | 30 | 3.02 | 3 | 0 | 0 | 8 | 8 | 0 | 0 | 44.2 | 30 | 15 | 15 | 14 | 35 | 4 | 1 |
| Cade Povich* | Bos | sp | 25 | 5.21 | 4 | 4 | 0 | 11 | 11 | 0 | 0 | 57.0 | 56 | 34 | 33 | 25 | 58 | 10 | 1 |
| Ryan Pressly | | mr | 36 | 3.70 | 3 | 4 | 7 | 45 | 0 | 0 | 0 | 48.2 | 45 | 28 | 20 | 13 | 45 | 5 | 2 |
| Quinn Priester | Ari | sp | 24 | 2.94 | 11 | 5 | 1 | 40 | 20 | 0 | 0 | 153.0 | 127 | 60 | 50 | 50 | 135 | 9 | 13 |
| A.J. Puk* | LAN | mr | 30 | 1.23 | 0 | 0 | 3 | 5 | 1 | 0 | 0 | 7.1 | 5 | 2 | 1 | 4 | 12 | 1 | 0 |
| Jose Quijada* | | mr | 29 | 7.98 | 2 | 2 | 1 | 23 | 2 | 0 | 0 | 29.1 | 28 | 27 | 26 | 18 | 35 | 1 | 2 |
| Jose Quintana* | Pit | sp | 36 | 6.05 | 7 | 4 | 0 | 18 | 16 | 0 | 0 | 86.1 | 105 | 62 | 58 | 35 | 65 | 6 | 6 |
| Cole Ragans* | Was | sp | 27 | 3.53 | 5 | 6 | 0 | 17 | 17 | 0 | 0 | 102.0 | 82 | 42 | 40 | 35 | 96 | 8 | 7 |
| Brooks Raley* | Mia | mr | 37 | 4.61 | 1 | 0 | 2 | 16 | 0 | 0 | 0 | 13.2 | 10 | 7 | 7 | 5 | 15 | 1 | 2 |
| Drew Rasmussen | Bos | sp | 29 | 3.79 | 12 | 10 | 0 | 31 | 31 | 1 | 0 | 182.2 | 154 | 85 | 77 | 50 | 196 | 14 | 6 |
| Dylan Ray | StL | sp | 24 | 7.45 | 2 | 19 | 0 | 26 | 26 | 0 | 0 | 118.1 | 143 | 104 | 98 | 58 | 102 | 16 | 8 |
| Robbie Ray* | Pit | sp | 33 | 3.99 | 12 | 8 | 0 | 30 | 30 | 1 | 0 | 160.1 | 125 | 81 | 71 | 67 | 163 | 24 | 6 |
| Sean Reid-Foley | Atl | mr | 29 | 10.22 | 1 | 3 | 1 | 13 | 0 | 0 | 0 | 12.1 | 20 | 14 | 14 | 10 | 15 | 2 | 1 |
| Patrick Reilly | StL | sp | 23 | 2.15 | 0 | 1 | 2 | 20 | 1 | 0 | 0 | 29.1 | 14 | 7 | 7 | 14 | 27 | 2 | 1 |
| Eric Reyzelman | | mr | 24 | 5.19 | 0 | 2 | 1 | 28 | 0 | 0 | 0 | 34.2 | 34 | 21 | 20 | 12 | 38 | 7 | 0 |
| Trevor Richards | NYN | mr | 32 | 3.55 | 4 | 0 | 2 | 50 | 4 | 0 | 0 | 83.2 | 51 | 34 | 33 | 38 | 94 | 11 | 2 |
| Lyon Richardson | NYA | sp | 25 | 5.09 | 1 | 2 | 0 | 4 | 4 | 0 | 0 | 23.0 | 21 | 14 | 13 | 10 | 32 | 5 | 0 |
| Ethan Roberts | Sac | mr | 27 | 3.59 | 1 | 1 | 1 | 51 | 0 | 0 | 0 | 77.2 | 75 | 34 | 31 | 22 | 72 | 11 | 7 |
| David Robertson | Mil | mr | 40 | 2.81 | 2 | 2 | 7 | 22 | 0 | 0 | 0 | 25.2 | 16 | 10 | 8 | 8 | 27 | 2 | 2 |
| Tekoah Roby | Sac | sp | 23 | 10.32 | 0 | 2 | 0 | 4 | 3 | 0 | 0 | 11.1 | 22 | 15 | 13 | 3 | 10 | 2 | 0 |
| Joe Rock* | Cle | sp | 24 | 4.15 | 1 | 1 | 0 | 20 | 2 | 0 | 0 | 30.1 | 34 | 18 | 14 | 12 | 31 | 5 | 0 |
| Kumar Rocker | SD | sp | 25 | 3.86 | 7 | 7 | 0 | 21 | 20 | 0 | 0 | 107.1 | 97 | 50 | 46 | 29 | 117 | 14 | 3 |
| Carlos Rodon* | | sp | 32 | 3.41 | 10 | 6 | 0 | 33 | 33 | 0 | 0 | 184.2 | 171 | 79 | 70 | 57 | 219 | 20 | 5 |
| Carlos F. Rodriguez | | sp | 23 | 3.57 | 3 | 4 | 0 | 19 | 15 | 0 | 0 | 88.1 | 81 | 37 | 35 | 33 | 79 | 13 | 5 |
| Eduardo Rodriguez* | Min | sp | 32 | 4.74 | 8 | 6 | 0 | 27 | 27 | 1 | 0 | 153.2 | 155 | 84 | 81 | 49 | 142 | 18 | 8 |
| Manuel Rodriguez | Pit | mr | 28 | 5.63 | 3 | 0 | 2 | 25 | 0 | 0 | 0 | 32.0 | 42 | 20 | 20 | 13 | 24 | 3 | 8 |
| Randy Rodriguez | Hou | mr | 25 | 2.83 | 8 | 5 | 1 | 61 | 5 | 0 | 0 | 105.0 | 79 | 39 | 33 | 42 | 97 | 8 | 2 |
| Wilking Rodriguez | Det | mr | 35 | 5.46 | 0 | 1 | 0 | 25 | 0 | 0 | 0 | 31.1 | 34 | 22 | 19 | 15 | 30 | 4 | 1 |
| Yariel Rodriguez | ChN | sp | 28 | 3.59 | 0 | 3 | 0 | 19 | 7 | 0 | 0 | 47.2 | 33 | 21 | 19 | 26 | 51 | 3 | 4 |
| Taylor Rogers* | Ari | mr | 34 | 3.42 | 5 | 3 | 3 | 72 | 0 | 0 | 0 | 84.1 | 78 | 37 | 32 | 45 | 95 | 7 | 10 |
| Trevor Rogers* | SF | sp | 27 | 3.84 | 5 | 5 | 0 | 13 | 13 | 0 | 0 | 72.2 | 54 | 37 | 31 | 30 | 79 | 7 | 4 |
| Tyler Rogers | Cle | mr | 34 | 2.42 | 3 | 5 | 16 | 60 | 0 | 0 | 0 | 63.1 | 60 | 21 | 17 | 16 | 55 | 5 | 9 |
| Drew Rom* | Bos | sp | 25 | 6.23 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 4.1 | 7 | 4 | 3 | 1 | 3 | 0 | 0 |
| Jordan Romano | | cl | 32 | 2.49 | 5 | 3 | 1 | 60 | 0 | 0 | 0 | 72.1 | 68 | 24 | 20 | 26 | 97 | 4 | 3 |
| JoJo Romero* | Min | mr | 28 | 4.81 | 5 | 2 | 1 | 67 | 0 | 0 | 0 | 78.2 | 76 | 45 | 42 | 29 | 75 | 15 | 6 |
| Landen Roupp | | mr | 26 | 3.96 | 5 | 5 | 2 | 36 | 19 | 0 | 0 | 127.1 | 112 | 66 | 56 | 63 | 102 | 13 | 9 |
| Joe Ryan | Min | sp | 29 | 4.78 | 14 | 11 | 0 | 33 | 33 | 1 | 1 | 179.0 | 172 | 105 | 95 | 59 | 177 | 29 | 9 |
| Andrew Saalfrank* | Mia | mr | 27 | 4.11 | 5 | 0 | 1 | 31 | 0 | 0 | 0 | 50.1 | 35 | 25 | 23 | 30 | 49 | 5 | 5 |
| Erik Sabrowski* | Pit | mr | 27 | 4.60 | 0 | 2 | 1 | 11 | 0 | 0 | 0 | 15.2 | 15 | 9 | 8 | 5 | 23 | 2 | 1 |
| Chris Sale* | LAA | sp | 36 | 3.81 | 12 | 4 | 0 | 21 | 21 | 0 | 0 | 125.1 | 105 | 55 | 53 | 29 | 158 | 12 | 6 |
| Cristopher Sanchez* | Tam | sp | 28 | 3.81 | 10 | 12 | 0 | 32 | 32 | 0 | 0 | 177.0 | 169 | 97 | 75 | 50 | 153 | 18 | 16 |
| Nick Sandlin | Col | mr | 28 | 0.60 | 0 | 0 | 0 | 14 | 0 | 0 | 0 | 15.0 | 10 | 3 | 1 | 3 | 17 | 2 | 1 |
| Cole Sands | | mr | 27 | 3.02 | 11 | 5 | 15 | 64 | 5 | 0 | 0 | 125.0 | 86 | 47 | 42 | 44 | 145 | 13 | 8 |
| Dennis Santana | Bal | mr | 29 | 3.51 | 10 | 6 | 21 | 81 | 0 | 0 | 0 | 97.1 | 83 | 44 | 38 | 41 | 91 | 8 | 8 |
| Tony Santillan | Col | mr | 28 | 3.48 | 3 | 2 | 4 | 36 | 0 | 0 | 0 | 41.1 | 30 | 17 | 16 | 15 | 49 | 5 | 5 |
| Gregory Santos | LAA | mr | 25 | 2.35 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 7.2 | 7 | 2 | 2 | 3 | 7 | 1 | 3 |
| Roki Sasaki | Col | sp | 23 | 5.22 | 3 | 3 | 0 | 10 | 10 | 0 | 0 | 50.0 | 57 | 36 | 29 | 14 | 56 | 10 | 3 |
| Tayler Saucedo* | Mil | mr | 32 | 7.15 | 3 | 0 | 1 | 28 | 0 | 0 | 0 | 22.2 | 26 | 19 | 18 | 12 | 22 | 3 | 0 |
| Max Scherzer | Cle | sp | 40 | 3.12 | 6 | 5 | 0 | 17 | 17 | 0 | 0 | 98.0 | 71 | 38 | 34 | 28 | 106 | 9 | 2 |
| Cam Schlittler | | sp | 24 | 6.29 | 1 | 3 | 1 | 31 | 0 | 0 | 0 | 34.1 | 30 | 25 | 24 | 17 | 29 | 4 | 2 |
| Clarke Schmidt | | sp | 29 | 5.07 | 5 | 4 | 0 | 17 | 16 | 0 | 0 | 92.1 | 86 | 56 | 52 | 42 | 90 | 10 | 7 |
| John Schreiber | | mr | 31 | 2.65 | 2 | 0 | 1 | 48 | 0 | 0 | 0 | 57.2 | 45 | 19 | 17 | 21 | 50 | 6 | 8 |
| Noah Schultz* | ChA | sp | 21 | 4.35 | 4 | 7 | 0 | 18 | 18 | 0 | 0 | 89.0 | 80 | 49 | 43 | 32 | 70 | 10 | 5 |
| Spencer Schwellenbach | Atl | sp | 25 | 4.64 | 4 | 5 | 0 | 18 | 18 | 0 | 0 | 108.2 | 102 | 59 | 56 | 34 | 106 | 14 | 7 |
| Christian Scott | NYA | sp | 26 | 4.50 | 1 | 5 | 0 | 6 | 6 | 0 | 0 | 38.0 | 30 | 19 | 19 | 15 | 40 | 4 | 4 |
| Tanner Scott* | NYN | cl | 30 | 1.76 | 6 | 5 | 18 | 57 | 0 | 0 | 0 | 76.2 | 49 | 25 | 15 | 30 | 97 | 6 | 8 |
| Tayler Scott | Phi | mr | 33 | 5.82 | 3 | 1 | 2 | 31 | 1 | 0 | 0 | 38.2 | 40 | 27 | 25 | 13 | 45 | 5 | 3 |
| JP Sears* | Cin | sp | 29 | 6.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.0 | 4 | 2 | 2 | 0 | 4 | 1 | 1 |
| Kodai Senga | | sp | 32 | 4.45 | 5 | 10 | 0 | 28 | 23 | 0 | 0 | 141.2 | 111 | 74 | 70 | 73 | 167 | 27 | 9 |
| Luis Severino | Tex | sp | 31 | 5.14 | 6 | 2 | 0 | 27 | 12 | 0 | 0 | 89.1 | 103 | 56 | 51 | 29 | 72 | 16 | 9 |
| Paul Sewald | Cle | cl | 35 | 2.30 | 1 | 1 | 1 | 12 | 0 | 0 | 0 | 15.2 | 11 | 4 | 4 | 3 | 16 | 2 | 0 |
| Carson Seymour | | sp | 26 | 3.78 | 0 | 0 | 1 | 26 | 2 | 0 | 0 | 33.1 | 33 | 18 | 14 | 13 | 30 | 5 | 4 |
| Emmet Sheehan | Ari | sp | 25 | 2.23 | 4 | 4 | 0 | 16 | 16 | 0 | 0 | 88.2 | 65 | 24 | 22 | 37 | 96 | 7 | 4 |
| Brady Singer | LAN | sp | 28 | 3.20 | 12 | 10 | 0 | 33 | 33 | 2 | 1 | 216.1 | 183 | 94 | 77 | 78 | 190 | 20 | 22 |
| Paul Skenes | SF | sp | 23 | 4.81 | 12 | 11 | 1 | 44 | 28 | 0 | 0 | 168.1 | 179 | 98 | 90 | 57 | 193 | 24 | 5 |
| Tarik Skubal* | Tam | sp | 28 | 2.49 | 17 | 7 | 0 | 32 | 32 | 1 | 1 | 205.2 | 166 | 65 | 57 | 37 | 246 | 21 | 9 |
| Justin Slaten | Det | mr | 27 | 3.23 | 4 | 2 | 8 | 56 | 3 | 0 | 0 | 78.0 | 59 | 32 | 28 | 22 | 88 | 8 | 7 |
| Ethan Small* | NYN | mr | 28 | 9.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 4.0 | 6 | 5 | 4 | 1 | 6 | 2 | 0 |
| Cade Smith | LAA | mr | 26 | 2.47 | 4 | 4 | 6 | 69 | 0 | 0 | 0 | 83.2 | 65 | 26 | 23 | 30 | 116 | 3 | 7 |
| Shane Smith | SD | mr | 25 | 2.02 | 2 | 1 | 0 | 38 | 0 | 0 | 0 | 53.1 | 44 | 16 | 12 | 14 | 55 | 4 | 6 |
| AJ Smith-Shawver | Tex | sp | 22 | 4.60 | 2 | 3 | 0 | 8 | 6 | 0 | 0 | 31.1 | 30 | 20 | 16 | 12 | 32 | 6 | 0 |
| Blake Snell* | | sp | 32 | 3.12 | 2 | 3 | 0 | 14 | 14 | 0 | 0 | 75.0 | 54 | 27 | 26 | 34 | 99 | 8 | 1 |
| Robby Snelling* | Bal | sp | 21 | 5.03 | 4 | 6 | 2 | 28 | 19 | 0 | 0 | 105.2 | 107 | 64 | 59 | 47 | 80 | 10 | 5 |
| Anthony Solometo* | StL | sp | 22 | 6.00 | 0 | 1 | 0 | 7 | 3 | 0 | 0 | 18.0 | 12 | 12 | 12 | 8 | 14 | 1 | 2 |
| Jose Soriano | Cin | mr | 26 | 4.45 | 13 | 12 | 0 | 31 | 31 | 0 | 0 | 176.0 | 154 | 88 | 87 | 72 | 176 | 16 | 11 |
| Mike Soroka | Ari | sp | 27 | 6.17 | 1 | 5 | 3 | 38 | 0 | 0 | 0 | 46.2 | 48 | 35 | 32 | 27 | 41 | 10 | 6 |
| Gregory Soto* | Tam | mr | 30 | 3.59 | 4 | 5 | 1 | 57 | 0 | 0 | 0 | 62.2 | 48 | 27 | 25 | 25 | 83 | 3 | 1 |
| Bennett Sousa* | | mr | 30 | 5.54 | 1 | 7 | 3 | 34 | 0 | 0 | 0 | 37.1 | 33 | 30 | 23 | 15 | 42 | 9 | 1 |
| Gabe Speier* | Was | mr | 30 | 4.11 | 6 | 6 | 1 | 30 | 12 | 0 | 0 | 92.0 | 90 | 46 | 42 | 25 | 96 | 16 | 8 |
| Mitch Spence | SF | sp | 27 | 4.60 | 4 | 3 | 2 | 23 | 12 | 0 | 0 | 86.0 | 104 | 63 | 44 | 26 | 62 | 8 | 5 |
| Jeffrey Springs* | Bos | sp | 32 | 3.16 | 11 | 7 | 0 | 32 | 32 | 0 | 0 | 168.0 | 136 | 61 | 59 | 45 | 158 | 18 | 6 |
| Brandon Sproat | NYN | sp | 24 | 3.14 | 8 | 9 | 0 | 32 | 32 | 0 | 0 | 163.1 | 137 | 70 | 57 | 66 | 152 | 12 | 7 |
| Ryne Stanek | | mr | 33 | 6.02 | 1 | 3 | 1 | 51 | 0 | 0 | 0 | 49.1 | 58 | 36 | 33 | 22 | 51 | 9 | 7 |
| Justin Steele* | Tex | sp | 29 | 1.54 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 11.2 | 7 | 2 | 2 | 6 | 15 | 2 | 1 |
| Trevor Stephan | Pit | mr | 29 | 1.17 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 7.2 | 8 | 2 | 1 | 4 | 14 | 0 | 0 |
| Robert Stephenson | | mr | 32 | 5.63 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 8.0 | 6 | 5 | 5 | 3 | 15 | 1 | 0 |
| Brock Stewart | Tex | mr | 33 | 1.48 | 5 | 1 | 18 | 49 | 0 | 0 | 0 | 61.0 | 30 | 11 | 10 | 19 | 85 | 2 | 3 |
| Matt Strahm* | | mr | 33 | 2.24 | 12 | 4 | 6 | 48 | 14 | 0 | 0 | 128.2 | 97 | 38 | 32 | 24 | 176 | 15 | 2 |
| Hunter Stratton | Mia | mr | 28 | 4.95 | 3 | 1 | 1 | 31 | 0 | 0 | 0 | 36.1 | 35 | 22 | 20 | 22 | 40 | 5 | 2 |
| Spencer Strider | Sea | sp | 26 | 2.42 | 10 | 5 | 0 | 23 | 23 | 0 | 0 | 137.2 | 105 | 41 | 37 | 34 | 183 | 11 | 4 |
| Marcus Stroman | Pit | sp | 34 | 5.97 | 2 | 3 | 0 | 7 | 7 | 0 | 0 | 37.2 | 41 | 30 | 25 | 14 | 33 | 4 | 1 |
| Tyler Stuart | SD | sp | 25 | 2.04 | 2 | 1 | 0 | 3 | 3 | 0 | 0 | 17.2 | 18 | 5 | 4 | 6 | 9 | 2 | 0 |
| Jose Suarez* | LAA | sp | 27 | 6.00 | 1 | 0 | 0 | 14 | 0 | 0 | 0 | 15.0 | 17 | 10 | 10 | 8 | 17 | 2 | 1 |
| Ranger Suarez* | ChN | sp | 29 | 3.17 | 14 | 3 | 0 | 27 | 27 | 0 | 0 | 176.0 | 143 | 66 | 62 | 52 | 153 | 16 | 10 |
| Robert Suarez | Tam | cl | 34 | 2.78 | 6 | 6 | 19 | 75 | 0 | 0 | 0 | 81.0 | 77 | 31 | 25 | 27 | 92 | 9 | 4 |
| Tomoyuki Sugano | ChN | sp | 35 | 1.13 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 8.0 | 4 | 1 | 1 | 1 | 3 | 0 | 1 |
| Brent Suter* | LAN | mr | 35 | 4.25 | 5 | 4 | 1 | 49 | 5 | 0 | 0 | 89.0 | 82 | 47 | 42 | 25 | 67 | 8 | 7 |
| Erik Swanson | Tor | mr | 31 | 5.00 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 9.0 | 9 | 5 | 5 | 1 | 13 | 1 | 0 |
| Jameson Taillon | Tam | sp | 33 | 3.16 | 7 | 6 | 0 | 22 | 22 | 0 | 0 | 128.0 | 120 | 50 | 45 | 35 | 106 | 15 | 4 |
| Dillon Tate | Tex | mr | 31 | 0.84 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 10.2 | 11 | 2 | 1 | 4 | 12 | 0 | 1 |
| Troy Taylor | SF | mr | 23 | 5.81 | 2 | 3 | 3 | 38 | 0 | 0 | 0 | 52.2 | 65 | 42 | 34 | 35 | 58 | 8 | 6 |
| Kai-Wei Teng | Hou | sp | 26 | 11.17 | 0 | 1 | 0 | 16 | 0 | 0 | 0 | 19.1 | 29 | 25 | 24 | 10 | 10 | 4 | 4 |
| Emiliano Teodo | Tex | sp | 24 | 0.00 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 2.1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
| Caleb Thielbar* | | mr | 38 | 5.37 | 3 | 4 | 5 | 59 | 0 | 0 | 0 | 62.0 | 70 | 38 | 37 | 29 | 77 | 9 | 3 |
| Keegan Thompson | Det | mr | 30 | 2.78 | 2 | 3 | 0 | 13 | 13 | 0 | 0 | 71.1 | 47 | 24 | 22 | 35 | 81 | 7 | 3 |
| Ryan Thompson | Bos | mr | 33 | 2.95 | 7 | 3 | 2 | 50 | 0 | 0 | 0 | 73.1 | 58 | 26 | 24 | 20 | 60 | 8 | 7 |
| Trent Thornton | Mil | mr | 31 | 3.65 | 1 | 4 | 2 | 28 | 0 | 0 | 0 | 37.0 | 35 | 18 | 15 | 9 | 30 | 4 | 3 |
| Blade Tidwell | Mil | sp | 24 | 6.52 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 9.2 | 10 | 8 | 7 | 4 | 7 | 5 | 1 |
| Jesus Tinoco | Atl | mr | 30 | 2.23 | 1 | 3 | 0 | 23 | 0 | 0 | 0 | 32.1 | 18 | 9 | 8 | 18 | 29 | 4 | 0 |
| Jonah Tong | Bos | sp | 22 | 5.00 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 9.0 | 9 | 5 | 5 | 4 | 12 | 2 | 1 |
| Michael Tonkin | NYA | mr | 35 | 4.58 | 0 | 2 | 2 | 8 | 0 | 0 | 0 | 17.2 | 19 | 15 | 9 | 9 | 10 | 2 | 2 |
| Justin Topa | | mr | 34 | 2.24 | 3 | 1 | 2 | 41 | 0 | 0 | 0 | 56.1 | 45 | 18 | 14 | 20 | 55 | 2 | 7 |
| Blake Treinen | | mr | 37 | 5.52 | 0 | 1 | 4 | 16 | 0 | 0 | 0 | 14.2 | 20 | 12 | 9 | 5 | 15 | 1 | 0 |
| Edwin Uceta | | mr | 27 | 1.46 | 7 | 4 | 17 | 68 | 0 | 0 | 0 | 98.1 | 55 | 22 | 16 | 38 | 116 | 8 | 0 |
| Miguel Ullola | StL | sp | 23 | 6.02 | 0 | 4 | 2 | 102 | 1 | 0 | 0 | 101.2 | 107 | 72 | 68 | 66 | 90 | 13 | 9 |
| Abner Uribe | Sea | mr | 25 | 2.04 | 4 | 1 | 2 | 52 | 0 | 0 | 0 | 66.1 | 29 | 16 | 15 | 38 | 89 | 3 | 5 |
| Jose Urquidy | Cle | sp | 30 | 18.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 4 | 2 | 2 | 1 | 1 | 0 | 0 |
| Framber Valdez* | LAA | sp | 31 | 3.16 | 12 | 13 | 0 | 32 | 32 | 4 | 2 | 216.1 | 170 | 82 | 76 | 79 | 224 | 18 | 33 |
| CJ Van Eyk | LAN | sp | 26 | 7.08 | 5 | 15 | 0 | 28 | 28 | 0 | 0 | 148.2 | 195 | 130 | 117 | 53 | 104 | 30 | 5 |
| Carlos Vargas | Sea | mr | 25 | 0.00 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 5.1 | 6 | 2 | 0 | 1 | 6 | 0 | 1 |
| Louie Varland | Atl | sp | 27 | 4.29 | 4 | 3 | 3 | 69 | 1 | 0 | 0 | 86.0 | 72 | 45 | 41 | 25 | 81 | 12 | 4 |
| Mike Vasil | SD | sp | 25 | 4.03 | 2 | 1 | 1 | 17 | 5 | 0 | 0 | 44.2 | 34 | 25 | 20 | 12 | 43 | 4 | 1 |
| Randy Vasquez | NYA | sp | 26 | 4.93 | 2 | 7 | 0 | 26 | 20 | 0 | 0 | 102.1 | 97 | 65 | 56 | 49 | 83 | 9 | 8 |
| Justin Verlander | | sp | 42 | 3.95 | 3 | 6 | 0 | 19 | 19 | 1 | 0 | 116.1 | 111 | 55 | 51 | 32 | 92 | 12 | 6 |
| Alex Vesia* | Atl | mr | 29 | 4.52 | 6 | 8 | 20 | 54 | 0 | 0 | 0 | 63.2 | 65 | 41 | 32 | 32 | 86 | 6 | 1 |
| Will Vest | Sac | mr | 30 | 2.97 | 3 | 5 | 12 | 77 | 0 | 0 | 0 | 78.2 | 60 | 30 | 26 | 29 | 73 | 3 | 4 |
| Victor Vodnik | LAA | mr | 25 | 2.88 | 4 | 3 | 1 | 27 | 0 | 0 | 0 | 34.1 | 25 | 14 | 11 | 15 | 36 | 5 | 5 |
| Michael Wacha | | sp | 33 | 5.33 | 9 | 10 | 0 | 36 | 24 | 0 | 0 | 153.2 | 180 | 98 | 91 | 50 | 133 | 19 | 15 |
| Hurston Waldrep | Atl | sp | 23 | 4.21 | 4 | 6 | 0 | 21 | 21 | 0 | 0 | 92.0 | 94 | 51 | 43 | 55 | 91 | 9 | 4 |
| Josh Walker* | Cin | mr | 30 | 4.71 | 2 | 1 | 3 | 29 | 0 | 0 | 0 | 42.0 | 37 | 24 | 22 | 12 | 40 | 5 | 3 |
| Ryan Walker | Phi | mr | 29 | 2.80 | 7 | 7 | 23 | 51 | 0 | 0 | 0 | 54.2 | 41 | 25 | 17 | 17 | 72 | 5 | 3 |
| Andrew Walters | Mia | mr | 24 | 0.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 3.2 | 1 | 0 | 0 | 4 | 4 | 0 | 0 |
| Will Warren | ChN | sp | 26 | 3.27 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 11.0 | 6 | 4 | 4 | 6 | 15 | 0 | 1 |
| Ryan Weathers* | Col | sp | 25 | 2.44 | 4 | 1 | 0 | 10 | 9 | 0 | 0 | 48.0 | 38 | 13 | 13 | 10 | 53 | 6 | 3 |
| Luke Weaver | Tam | mr | 31 | 4.15 | 5 | 1 | 5 | 63 | 0 | 0 | 0 | 80.1 | 73 | 38 | 37 | 34 | 96 | 10 | 3 |
| Jacob Webb | Mil | mr | 31 | 4.38 | 1 | 4 | 1 | 73 | 0 | 0 | 0 | 84.1 | 91 | 45 | 41 | 36 | 83 | 8 | 3 |
| Logan Webb | Sac | sp | 28 | 3.86 | 11 | 14 | 0 | 34 | 34 | 1 | 0 | 209.2 | 194 | 92 | 90 | 55 | 169 | 20 | 18 |
| Greg Weissert | Mia | mr | 30 | 4.87 | 5 | 3 | 0 | 56 | 0 | 0 | 0 | 68.1 | 60 | 41 | 37 | 25 | 71 | 10 | 3 |
| Tyler Wells | NYA | sp | 30 | 5.40 | 2 | 3 | 0 | 5 | 5 | 0 | 0 | 35.0 | 38 | 24 | 21 | 7 | 22 | 7 | 2 |
| Hayden Wesneski | NYA | mr | 27 | 2.76 | 3 | 4 | 0 | 13 | 8 | 1 | 1 | 62.0 | 37 | 20 | 19 | 25 | 58 | 5 | 1 |
| Cameron Weston | Tor | sp | 24 | 5.78 | 5 | 6 | 0 | 19 | 14 | 0 | 0 | 85.2 | 89 | 59 | 55 | 35 | 83 | 11 | 1 |
| Zack Wheeler | Phi | sp | 35 | 3.71 | 7 | 10 | 0 | 26 | 26 | 4 | 0 | 177.0 | 145 | 83 | 73 | 63 | 180 | 13 | 5 |
| Carson Whisenhunt* | KC | sp | 24 | 5.08 | 1 | 5 | 1 | 11 | 10 | 0 | 0 | 51.1 | 50 | 32 | 29 | 17 | 49 | 6 | 2 |
| Forrest Whitley | Cin | mr | 27 | 2.63 | 2 | 0 | 1 | 16 | 0 | 0 | 0 | 13.2 | 6 | 4 | 4 | 8 | 14 | 1 | 0 |
| Garrett Whitlock | Sac | mr | 29 | 4.03 | 9 | 14 | 0 | 33 | 33 | 1 | 1 | 196.2 | 177 | 99 | 88 | 45 | 202 | 21 | 6 |
| Jordan Wicks* | | sp | 25 | 13.50 | 0 | 1 | 0 | 3 | 1 | 0 | 0 | 6.0 | 9 | 12 | 9 | 7 | 6 | 2 | 1 |
| Nathan Wiles | Bal | mr | 26 | 6.29 | 3 | 2 | 0 | 27 | 0 | 0 | 0 | 34.1 | 42 | 27 | 24 | 5 | 18 | 9 | 2 |
| Devin Williams | Min | cl | 30 | 1.12 | 7 | 4 | 29 | 54 | 0 | 0 | 0 | 64.1 | 36 | 14 | 8 | 23 | 86 | 1 | 2 |
| Gavin Williams | Ari | sp | 25 | 3.93 | 7 | 6 | 0 | 34 | 34 | 0 | 0 | 174.0 | 147 | 78 | 76 | 63 | 164 | 16 | 8 |
| Allan Winans | SD | sp | 29 | 4.20 | 3 | 3 | 0 | 18 | 13 | 0 | 0 | 79.1 | 75 | 45 | 37 | 26 | 55 | 6 | 4 |
| Josh Winckowski | KC | mr | 27 | 3.12 | 3 | 5 | 0 | 13 | 13 | 0 | 0 | 80.2 | 69 | 34 | 28 | 16 | 63 | 8 | 4 |
| Keaton Winn | SF | sp | 27 | 0.00 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 6.1 | 2 | 0 | 0 | 1 | 9 | 0 | 0 |
| Bryan Woo | Pit | sp | 25 | 3.61 | 9 | 9 | 0 | 32 | 32 | 0 | 0 | 187.0 | 162 | 81 | 75 | 31 | 161 | 22 | 7 |
| Brandon Woodruff | Bos | sp | 32 | 2.88 | 6 | 3 | 0 | 13 | 13 | 0 | 0 | 81.1 | 68 | 29 | 26 | 29 | 84 | 8 | 2 |
| Jaden Woods* | SF | mr | 23 | 6.61 | 3 | 5 | 1 | 27 | 0 | 0 | 0 | 32.2 | 44 | 25 | 24 | 12 | 17 | 2 | 3 |
| Simeon Woods Richardso | Pit | sp | 24 | 5.77 | 1 | 4 | 0 | 9 | 9 | 1 | 1 | 48.1 | 48 | 34 | 31 | 15 | 45 | 6 | 4 |
| Kyle Wright | Col | sp | 29 | 4.20 | 0 | 2 | 0 | 2 | 2 | 1 | 0 | 15.0 | 15 | 9 | 7 | 3 | 14 | 4 | 1 |
| Justin Wrobleski* | Atl | sp | 24 | 3.57 | 0 | 1 | 1 | 13 | 1 | 0 | 0 | 22.2 | 21 | 10 | 9 | 10 | 23 | 4 | 2 |
| Yoshinobu Yamamoto | Col | sp | 26 | 2.53 | 16 | 12 | 0 | 32 | 32 | 3 | 2 | 213.2 | 151 | 76 | 60 | 45 | 233 | 20 | 4 |
| Ryan Yarbrough* | NYA | mr | 33 | 4.75 | 7 | 9 | 2 | 36 | 15 | 0 | 0 | 121.1 | 109 | 82 | 64 | 50 | 89 | 24 | 5 |
| Kirby Yates | Min | cl | 38 | 2.17 | 4 | 0 | 2 | 49 | 0 | 0 | 0 | 58.0 | 47 | 16 | 14 | 31 | 66 | 3 | 8 |
| Craig Yoho | Bos | mr | 25 | 4.22 | 2 | 2 | 3 | 69 | 0 | 0 | 0 | 81.0 | 70 | 42 | 38 | 45 | 89 | 7 | 6 |
| Brandon Young | Mia | sp | 26 | 3.92 | 1 | 2 | 0 | 9 | 2 | 0 | 0 | 20.2 | 24 | 9 | 9 | 5 | 11 | 2 | 2 |
| Rob Zastryzny* | | mr | 33 | 4.39 | 7 | 2 | 1 | 34 | 9 | 0 | 0 | 69.2 | 69 | 42 | 34 | 25 | 59 | 10 | 3 |
| Ryan Zeferjahn | | mr | 27 | 3.70 | 5 | 2 | 5 | 68 | 0 | 0 | 0 | 92.1 | 72 | 43 | 38 | 43 | 91 | 6 | 7 |
| Angel Zerpa* | | mr | 25 | 7.59 | 2 | 2 | 2 | 27 | 0 | 0 | 0 | 32.0 | 45 | 28 | 27 | 11 | 26 | 5 | 2 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| Andrew Abbott* | Det | sp | 26 | 29 | 11 | 1 | 5 | 6 | 0 | 0 | 3 | 7.3 | 3.7 | 11.2 | 9.0 | 0.8 | 2.5 | 1.22 |
| Bryan Abreu | Sea | mr | 28 | 23 | 2 | 3 | 2 | 3 | 0 | 0 | 2 | 9.0 | 4.1 | 13.3 | 12.6 | 1.2 | 3.1 | 1.45 |
| Jason Adam | Ari | mr | 33 | 14 | 3 | 0 | 3 | 1 | 1 | 0 | 2 | 6.8 | 2.9 | 10.1 | 10.4 | 0.6 | 3.6 | 1.08 |
| Zach Agnos | NYA | mr | 24 | 4 | 2 | 3 | 2 | 3 | 0 | 2 | 7 | 9.9 | 3.6 | 13.7 | 7.8 | 2.3 | 2.2 | 1.50 |
| Keegan Akin* | Phi | mr | 30 | 3 | 1 | 0 | 1 | 2 | 0 | 0 | 2 | 5.8 | 2.4 | 8.3 | 11.0 | 1.2 | 4.6 | 0.91 |
| Jorge Alcala | | mr | 29 | 2 | 2 | 0 | 0 | 1 | 1 | 0 | 3 | 6.4 | 4.0 | 10.3 | 10.0 | 1.5 | 2.5 | 1.15 |
| Sandy Alcantara | Pit | sp | 29 | 36 | 10 | 0 | 8 | 3 | 0 | 0 | 1 | 8.1 | 2.4 | 10.9 | 8.4 | 0.5 | 3.5 | 1.17 |
| Sam Aldegheri* | Atl | sp | 23 | 6 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 11.2 | 2.3 | 14.4 | 7.9 | 0.9 | 3.4 | 1.50 |
| Franco Aleman | KC | mr | 25 | 8 | 5 | 0 | 3 | 1 | 0 | 0 | 5 | 8.3 | 5.7 | 14.7 | 7.2 | 0.9 | 1.3 | 1.56 |
| Scott Alexander* | NYN | mr | 35 | 2 | 4 | 0 | 3 | 0 | 0 | 0 | 1 | 6.7 | 2.4 | 9.7 | 6.1 | 0.6 | 2.5 | 1.02 |
| Tyler Alexander* | ChA | mr | 30 | 14 | 2 | 1 | 1 | 0 | 0 | 0 | 3 | 10.5 | 2.1 | 12.8 | 6.6 | 1.4 | 3.2 | 1.40 |
| Logan Allen* | Was | sp | 28 | 21 | 12 | 0 | 4 | 8 | 0 | 0 | 4 | 9.1 | 3.1 | 12.4 | 6.1 | 1.2 | 1.9 | 1.36 |
| Elvis Alvarado | Tex | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.0 | 2.6 | 9.6 | 10.5 | 0.9 | 4.0 | 1.06 |
| Jose Alvarado* | Ari | mr | 30 | 5 | 1 | 2 | 2 | 0 | 1 | 0 | 1 | 8.9 | 5.4 | 14.8 | 11.3 | 0.3 | 2.1 | 1.59 |
| Kyle Amendt | Atl | mr | 25 | 4 | 1 | 0 | 0 | 3 | 1 | 1 | 0 | 7.4 | 4.9 | 12.3 | 9.5 | 2.1 | 2.0 | 1.37 |
| Ian Anderson | NYA | sp | 27 | 16 | 3 | 5 | 2 | 4 | 0 | 0 | 2 | 10.2 | 5.2 | 15.7 | 6.7 | 1.1 | 1.3 | 1.71 |
| Tyler Anderson* | Tor | sp | 35 | 17 | 3 | 0 | 2 | 1 | 0 | 0 | 5 | 8.2 | 2.7 | 11.1 | 7.2 | 0.6 | 2.7 | 1.21 |
| Shawn Armstrong | Ari | mr | 34 | 4 | 1 | 4 | 0 | 0 | 1 | 0 | 2 | 7.8 | 4.1 | 11.9 | 8.5 | 0.6 | 2.1 | 1.33 |
| Spencer Arrighetti | Phi | sp | 25 | 6 | 1 | 0 | 0 | 2 | 1 | 0 | 1 | 8.2 | 3.3 | 11.5 | 9.0 | 1.2 | 2.8 | 1.27 |
| Aaron Ashby* | Sea | mr | 27 | 13 | 5 | 0 | 1 | 8 | 0 | 0 | 2 | 10.9 | 6.7 | 17.8 | 11.2 | 1.5 | 1.7 | 1.96 |
| Braxton Ashcraft | Atl | sp | 25 | 24 | 6 | 0 | 5 | 4 | 4 | 0 | 1 | 8.2 | 2.2 | 10.7 | 7.4 | 1.0 | 3.4 | 1.16 |
| Graham Ashcraft | Was | sp | 27 | 7 | 2 | 0 | 8 | 2 | 0 | 0 | 3 | 6.9 | 3.0 | 11.3 | 7.8 | 0.5 | 2.6 | 1.10 |
| Sam Bachman | Tor | sp | 25 | 6 | 3 | 0 | 5 | 3 | 1 | 0 | 0 | 7.7 | 3.7 | 12.5 | 7.3 | 0.4 | 1.9 | 1.27 |
| Henry Baez | Tor | sp | 22 | 16 | 4 | 0 | 1 | 0 | 1 | 0 | 1 | 13.1 | 3.8 | 17.0 | 5.5 | 2.1 | 1.5 | 1.87 |
| Bryan Baker | Col | mr | 30 | 8 | 2 | 1 | 1 | 1 | 0 | 0 | 3 | 8.8 | 3.6 | 12.7 | 6.8 | 0.7 | 1.9 | 1.39 |
| Tanner Banks* | SD | mr | 33 | 15 | 3 | 0 | 0 | 1 | 1 | 0 | 3 | 8.2 | 3.0 | 11.1 | 9.2 | 0.7 | 3.1 | 1.24 |
| Scott Barlow | ChN | mr | 32 | 7 | 2 | 0 | 5 | 3 | 0 | 1 | 4 | 6.5 | 5.0 | 12.0 | 9.4 | 1.3 | 1.9 | 1.28 |
| Mason Barnett | StL | sp | 24 | 63 | 6 | 0 | 10 | 8 | 2 | 0 | 7 | 8.5 | 3.8 | 12.8 | 7.8 | 0.9 | 2.1 | 1.36 |
| Chris Bassitt | Mil | sp | 36 | 30 | 11 | 0 | 18 | 4 | 2 | 1 | 12 | 9.3 | 4.6 | 14.8 | 7.5 | 1.1 | 1.6 | 1.54 |
| Brady Basso* | Min | sp | 27 | 1 | 1 | 0 | 0 | 3 | 0 | 0 | 2 | 8.2 | 2.3 | 10.6 | 6.7 | 1.2 | 2.9 | 1.17 |
| Felix Bautista | ChN | cl | 30 | 4 | 3 | 0 | 1 | 2 | 2 | 1 | 2 | 4.5 | 3.3 | 8.0 | 11.3 | 0.5 | 3.4 | 0.87 |
| Shane Baz | Bal | sp | 26 | 30 | 8 | 0 | 5 | 7 | 1 | 0 | 7 | 8.1 | 3.7 | 12.0 | 8.8 | 0.5 | 2.4 | 1.30 |
| Eduard Bazardo | Pit | mr | 29 | 14 | 3 | 0 | 5 | 2 | 0 | 0 | 2 | 10.0 | 2.7 | 13.4 | 9.4 | 1.0 | 3.5 | 1.41 |
| Tristan Beck | SF | mr | 29 | 11 | 3 | 1 | 4 | 5 | 0 | 0 | 4 | 8.1 | 3.2 | 11.6 | 8.8 | 1.1 | 2.7 | 1.25 |
| Ian Bedell | ChA | sp | 25 | 5 | 1 | 0 | 2 | 2 | 0 | 0 | 2 | 13.5 | 4.6 | 18.6 | 7.9 | 2.8 | 1.7 | 2.01 |
| David Bednar | LAA | cl | 30 | 7 | 3 | 0 | 0 | 3 | 0 | 0 | 1 | 6.9 | 2.2 | 9.2 | 10.5 | 0.7 | 4.7 | 1.02 |
| Jalen Beeks* | LAN | mr | 31 | 7 | 6 | 1 | 4 | 8 | 0 | 0 | 5 | 10.0 | 3.9 | 14.1 | 7.2 | 0.8 | 1.9 | 1.54 |
| Clayton Beeter | Col | sp | 26 | 16 | 8 | 0 | 5 | 13 | 2 | 1 | 5 | 10.0 | 4.3 | 14.7 | 10.0 | 1.5 | 2.3 | 1.59 |
| Nigel Belgrave | | mr | 23 | 1 | 0 | 7 | 3 | 13 | 0 | 0 | 5 | 5.5 | 5.5 | 11.6 | 7.7 | 1.0 | 1.4 | 1.23 |
| Brayan Bello | Mil | sp | 26 | 16 | 11 | 0 | 6 | 2 | 0 | 0 | 3 | 7.9 | 2.8 | 11.1 | 8.1 | 0.9 | 2.9 | 1.19 |
| Valente Bellozo | Tor | sp | 25 | 8 | 3 | 0 | 1 | 4 | 0 | 1 | 1 | 9.5 | 3.0 | 12.6 | 6.5 | 1.0 | 2.2 | 1.38 |
| Anthony Bender | Mil | mr | 30 | 5 | 4 | 1 | 4 | 2 | 0 | 0 | 1 | 7.9 | 4.6 | 13.4 | 8.8 | 0.4 | 1.9 | 1.39 |
| Ryan Bergert | Hou | sp | 25 | 12 | 2 | 1 | 2 | 1 | 0 | 0 | 2 | 11.8 | 3.7 | 16.1 | 8.0 | 2.3 | 2.2 | 1.72 |
| Brennan Bernardino* | | mr | 33 | 6 | 5 | 0 | 9 | 7 | 0 | 1 | 0 | 8.4 | 2.7 | 12.5 | 8.7 | 0.8 | 3.2 | 1.23 |
| Jose Berrios | | sp | 31 | 26 | 5 | 0 | 14 | 1 | 1 | 1 | 6 | 8.8 | 2.2 | 11.7 | 8.2 | 1.2 | 3.8 | 1.21 |
| Prelander Berroa | SF | mr | 25 | 5 | 2 | 0 | 2 | 1 | 0 | 0 | 3 | 9.6 | 5.7 | 15.6 | 11.1 | 1.7 | 1.9 | 1.70 |
| Tanner Bibee | Was | sp | 26 | 25 | 6 | 0 | 4 | 2 | 0 | 0 | 6 | 7.6 | 2.3 | 10.1 | 9.5 | 1.4 | 4.1 | 1.10 |
| Phil Bickford | ChN | mr | 29 | 22 | 5 | 0 | 5 | 1 | 0 | 0 | 3 | 5.8 | 2.2 | 8.3 | 8.7 | 1.4 | 4.0 | 0.89 |
| Osvaldo Bido | | sp | 29 | 32 | 10 | 0 | 13 | 6 | 2 | 1 | 7 | 8.3 | 4.7 | 13.9 | 8.7 | 0.9 | 1.8 | 1.45 |
| Shane Bieber | Hou | sp | 30 | 11 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 8.9 | 3.9 | 12.8 | 9.4 | 0.8 | 2.4 | 1.43 |
| Hayden Birdsong | Bos | sp | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 9.4 | 8.2 | 17.6 | 3.5 | 0.0 | 0.4 | 1.96 |
| Ronel Blanco | Col | sp | 31 | 3 | 3 | 0 | 2 | 1 | 0 | 0 | 1 | 7.2 | 3.6 | 11.2 | 8.4 | 0.8 | 2.4 | 1.20 |
| A.J. Blubaugh | | sp | 24 | 21 | 8 | 0 | 8 | 7 | 2 | 2 | 5 | 7.3 | 2.7 | 10.6 | 8.1 | 1.0 | 3.0 | 1.11 |
| Ryan Borucki* | LAN | mr | 31 | 10 | 4 | 1 | 6 | 5 | 1 | 0 | 3 | 7.3 | 6.2 | 14.3 | 9.8 | 1.1 | 1.6 | 1.49 |
| Matt Boyd* | Tex | sp | 34 | 11 | 5 | 1 | 3 | 0 | 1 | 0 | 1 | 6.0 | 2.6 | 8.8 | 8.8 | 1.2 | 3.4 | 0.96 |
| Joe Boyle | NYA | sp | 25 | 59 | 2 | 0 | 9 | 18 | 2 | 2 | 9 | 9.5 | 10.4 | 20.5 | 10.0 | 1.4 | 1.0 | 2.21 |
| Kyle Bradish | Bal | sp | 28 | 4 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 5.5 | 1.6 | 7.6 | 10.8 | 0.2 | 6.8 | 0.79 |
| Taj Bradley | | sp | 24 | 20 | 7 | 0 | 9 | 7 | 0 | 0 | 9 | 8.0 | 3.3 | 11.8 | 9.5 | 1.3 | 2.8 | 1.26 |
| Matt Brash | Col | mr | 27 | 16 | 6 | 0 | 3 | 12 | 3 | 0 | 1 | 7.9 | 4.4 | 12.7 | 12.7 | 0.8 | 2.9 | 1.37 |
| Ryan Brasier | Pit | mr | 37 | 7 | 2 | 1 | 3 | 0 | 0 | 0 | 1 | 8.4 | 1.3 | 10.4 | 7.3 | 0.9 | 5.5 | 1.08 |
| Mitch Bratt* | StL | sp | 21 | 8 | 2 | 0 | 2 | 0 | 0 | 0 | 3 | 7.4 | 2.5 | 10.0 | 7.0 | 1.2 | 2.8 | 1.09 |
| Lucas Braun | | sp | 23 | 15 | 2 | 2 | 3 | 0 | 0 | 0 | 1 | 11.6 | 3.6 | 15.8 | 9.1 | 0.8 | 2.5 | 1.69 |
| Huascar Brazoban | NYN | mr | 35 | 17 | 0 | 0 | 2 | 10 | 0 | 0 | 3 | 7.5 | 4.8 | 12.5 | 8.9 | 0.6 | 1.8 | 1.37 |
| John Brebbia | ChA | mr | 35 | 7 | 2 | 2 | 2 | 0 | 0 | 0 | 2 | 8.4 | 4.6 | 13.4 | 10.3 | 0.7 | 2.2 | 1.45 |
| Jhony Brito | ChA | mr | 27 | 22 | 5 | 0 | 3 | 0 | 0 | 0 | 2 | 7.2 | 1.9 | 9.3 | 6.5 | 1.1 | 3.4 | 1.01 |
| Ben Brown | Sea | sp | 25 | 30 | 12 | 3 | 6 | 6 | 2 | 1 | 4 | 7.2 | 4.3 | 11.8 | 10.0 | 1.0 | 2.3 | 1.27 |
| Hunter Brown | Mia | sp | 26 | 42 | 8 | 0 | 8 | 4 | 1 | 0 | 4 | 7.7 | 3.0 | 11.1 | 9.9 | 0.9 | 3.3 | 1.19 |
| Kris Bubic* | Tex | mr | 27 | 11 | 2 | 0 | 2 | 1 | 0 | 1 | 4 | 6.6 | 3.1 | 9.9 | 8.8 | 0.6 | 2.8 | 1.07 |
| Walker Buehler | Phi | sp | 30 | 32 | 7 | 0 | 8 | 1 | 1 | 1 | 4 | 6.9 | 1.7 | 9.1 | 8.3 | 0.9 | 4.8 | 0.96 |
| J.B. Bukauskas | LAN | mr | 28 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.1 | 0.0 | 10.1 | 10.1 | 0.0 | 99.0 | 1.13 |
| Aaron Bummer* | | mr | 31 | 14 | 3 | 3 | 4 | 2 | 0 | 1 | 1 | 7.0 | 2.4 | 9.8 | 11.0 | 0.5 | 4.6 | 1.04 |
| Brock Burke* | | mr | 28 | 4 | 2 | 2 | 2 | 1 | 2 | 0 | 4 | 7.9 | 3.3 | 11.4 | 9.4 | 0.7 | 2.9 | 1.24 |
| Sean Burke | LAA | sp | 25 | 10 | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 10.0 | 3.6 | 13.6 | 10.0 | 1.7 | 2.8 | 1.52 |
| Corbin Burnes | Ari | sp | 30 | 22 | 5 | 0 | 4 | 2 | 0 | 0 | 2 | 6.9 | 2.3 | 9.6 | 9.0 | 0.5 | 3.9 | 1.03 |
| Tanner Burns | ChA | mr | 26 | 45 | 7 | 0 | 12 | 16 | 2 | 0 | 2 | 8.9 | 5.6 | 15.2 | 7.3 | 1.1 | 1.3 | 1.61 |
| Ryan Burr | KC | mr | 31 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.9 | 1.9 | 4.8 | 16.4 | 1.0 | 8.5 | 0.54 |
| Mike Burrows | Sea | sp | 25 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 11.6 | 2.6 | 15.4 | 9.0 | 1.3 | 3.5 | 1.57 |
| Jose Butto | | mr | 27 | 17 | 3 | 0 | 6 | 2 | 2 | 1 | 0 | 8.5 | 5.8 | 15.2 | 7.9 | 1.5 | 1.3 | 1.60 |
| Edward Cabrera | Atl | sp | 27 | 25 | 9 | 1 | 2 | 3 | 0 | 0 | 1 | 7.5 | 4.3 | 12.0 | 9.6 | 1.3 | 2.2 | 1.31 |
| Jean Cabrera | Tor | sp | 23 | 4 | 4 | 0 | 6 | 2 | 1 | 0 | 2 | 10.6 | 4.9 | 16.6 | 7.2 | 1.5 | 1.5 | 1.72 |
| Noah Cameron* | Cin | sp | 25 | 16 | 11 | 1 | 4 | 5 | 0 | 0 | 5 | 7.6 | 2.8 | 10.6 | 7.8 | 1.0 | 2.8 | 1.15 |
| Griffin Canning | StL | sp | 29 | 11 | 1 | 0 | 2 | 3 | 0 | 1 | 3 | 10.4 | 4.1 | 14.8 | 5.8 | 1.8 | 1.4 | 1.61 |
| Jonathan Cannon | SD | sp | 24 | 3 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 10.2 | 4.5 | 15.1 | 8.2 | 0.4 | 1.8 | 1.64 |
| Yennier Cano | ChN | mr | 31 | 9 | 1 | 3 | 3 | 1 | 2 | 3 | 1 | 5.6 | 3.4 | 9.2 | 8.5 | 0.5 | 2.5 | 0.99 |
| Joey Cantillo* | SF | sp | 25 | 15 | 6 | 0 | 1 | 8 | 1 | 0 | 2 | 10.2 | 6.2 | 16.5 | 10.1 | 0.9 | 1.6 | 1.82 |
| Ben Casparius | ChA | sp | 26 | 24 | 4 | 1 | 3 | 5 | 1 | 1 | 2 | 9.8 | 6.0 | 16.2 | 8.4 | 1.5 | 1.4 | 1.75 |
| Jose Castillo* | ChN | mr | 29 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 7.0 | 5.5 | 13.0 | 6.5 | 1.0 | 1.2 | 1.39 |
| Luis Castillo | Bos | sp | 32 | 15 | 12 | 0 | 6 | 1 | 0 | 0 | 0 | 7.1 | 2.7 | 10.0 | 9.9 | 0.6 | 3.6 | 1.09 |
| Miguel Castro | Min | mr | 30 | 3 | 1 | 1 | 2 | 2 | 0 | 0 | 0 | 9.0 | 4.2 | 13.8 | 9.0 | 1.7 | 2.1 | 1.47 |
| Cade Cavalli | Sac | sp | 26 | 16 | 12 | 2 | 13 | 0 | 2 | 0 | 3 | 7.3 | 3.6 | 11.9 | 9.4 | 0.9 | 2.6 | 1.22 |
| Dylan Cease | Mil | sp | 29 | 19 | 14 | 0 | 9 | 13 | 1 | 0 | 5 | 6.9 | 3.8 | 11.2 | 10.2 | 0.9 | 2.7 | 1.19 |
| Slade Cecconi | SD | sp | 26 | 36 | 6 | 0 | 7 | 5 | 0 | 0 | 7 | 8.1 | 2.7 | 11.2 | 6.3 | 1.1 | 2.4 | 1.20 |
| Andrew Chafin* | Sac | mr | 35 | 2 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 11.2 | 6.1 | 17.3 | 10.4 | 0.7 | 1.7 | 1.92 |
| Bubba Chandler | SF | sp | 22 | 9 | 3 | 0 | 2 | 0 | 1 | 0 | 3 | 8.6 | 4.9 | 13.7 | 8.2 | 0.9 | 1.7 | 1.49 |
| Aroldis Chapman* | LAA | mr | 37 | 13 | 2 | 1 | 3 | 5 | 1 | 0 | 2 | 7.9 | 6.2 | 14.5 | 13.3 | 1.9 | 2.1 | 1.57 |
| Jesse Chavez | ChA | mr | 41 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.4 | 3.5 | 12.0 | 8.0 | 0.9 | 2.3 | 1.33 |
| Po-Yu Chen | StL | sp | 23 | 4 | 1 | 0 | 2 | 2 | 1 | 0 | 0 | 10.9 | 1.8 | 13.3 | 5.6 | 0.7 | 3.2 | 1.40 |
| Jack Choate* | ChN | sp | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 6.8 | 6.8 | 13.5 | 0.0 | 2.0 | 0.75 |
| Marc Church | Mil | mr | 24 | 6 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 8.0 | 3.9 | 11.9 | 9.0 | 1.5 | 2.3 | 1.32 |
| Aaron Civale | Min | sp | 30 | 3 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 8.3 | 5.2 | 14.2 | 9.0 | 2.1 | 1.7 | 1.50 |
| Emmanuel Clase | Sea | cl | 27 | 2 | 0 | 1 | 3 | 1 | 0 | 0 | 1 | 7.7 | 1.8 | 10.1 | 9.6 | 0.6 | 5.2 | 1.06 |
| Garrett Cleavinger* | Ari | mr | 31 | 11 | 5 | 1 | 7 | 5 | 0 | 1 | 0 | 7.1 | 4.6 | 12.4 | 9.3 | 0.9 | 2.0 | 1.30 |
| Adisyn Coffey | Hou | mr | 26 | 4 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 11.5 | 6.1 | 17.6 | 4.5 | 1.6 | 0.7 | 1.95 |
| Roansy Contreras | Det | mr | 25 | 41 | 7 | 0 | 1 | 9 | 1 | 0 | 7 | 7.6 | 3.0 | 10.7 | 8.4 | 1.1 | 2.8 | 1.18 |
| Nestor Cortes* | | sp | 30 | 15 | 5 | 0 | 1 | 0 | 0 | 0 | 2 | 7.8 | 2.8 | 10.8 | 7.8 | 0.9 | 2.8 | 1.18 |
| Danny Coulombe* | Det | mr | 35 | 13 | 3 | 2 | 1 | 3 | 0 | 0 | 2 | 7.2 | 3.0 | 10.3 | 9.5 | 1.3 | 3.2 | 1.13 |
| Austin Cox* | ChA | mr | 28 | 6 | 2 | 1 | 3 | 1 | 0 | 0 | 0 | 9.1 | 5.1 | 14.8 | 6.3 | 0.6 | 1.2 | 1.58 |
| Cooper Criswell | Mil | sp | 28 | 3 | 2 | 2 | 5 | 2 | 0 | 1 | 2 | 11.0 | 2.1 | 14.4 | 6.7 | 1.9 | 3.1 | 1.46 |
| Garrett Crochet* | Cle | sp | 26 | 16 | 5 | 0 | 4 | 7 | 1 | 1 | 4 | 6.9 | 3.0 | 10.1 | 12.1 | 0.4 | 4.0 | 1.10 |
| Declan Cronin | Tam | mr | 27 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 8.7 | 2.0 | 10.9 | 7.7 | 1.0 | 3.9 | 1.18 |
| Fernando Cruz | Hou | mr | 35 | 23 | 8 | 3 | 5 | 5 | 0 | 0 | 3 | 6.2 | 4.8 | 11.4 | 12.5 | 0.8 | 2.6 | 1.22 |
| Yoniel Curet | Sac | sp | 22 | 6 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 9.0 | 6.4 | 15.4 | 11.1 | 1.7 | 1.7 | 1.71 |
| Xzavion Curry | SF | sp | 26 | 7 | 6 | 0 | 2 | 0 | 0 | 1 | 0 | 10.1 | 3.1 | 13.5 | 7.1 | 2.0 | 2.3 | 1.47 |
| Caden Dana | NYA | sp | 21 | 11 | 1 | 0 | 2 | 2 | 0 | 0 | 1 | 10.0 | 1.2 | 12.0 | 7.5 | 1.2 | 6.0 | 1.25 |
| Davis Daniel | Phi | sp | 28 | 26 | 1 | 0 | 3 | 3 | 0 | 0 | 3 | 8.9 | 2.7 | 11.8 | 6.3 | 1.2 | 2.3 | 1.29 |
| Hagen Danner | Cin | mr | 26 | 3 | 2 | 1 | 2 | 1 | 0 | 0 | 1 | 10.0 | 3.2 | 13.8 | 10.3 | 1.3 | 3.2 | 1.47 |
| Yu Darvish | | sp | 38 | 12 | 3 | 0 | 4 | 2 | 0 | 0 | 0 | 7.2 | 2.1 | 9.9 | 8.8 | 1.3 | 4.1 | 1.04 |
| Duncan Davitt | StL | sp | 25 | 12 | 4 | 1 | 6 | 4 | 0 | 0 | 6 | 9.6 | 3.3 | 13.5 | 6.9 | 1.2 | 2.1 | 1.43 |
| Enyel de los Santos | Mil | mr | 29 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 1 | 8.4 | 4.8 | 13.8 | 8.7 | 1.5 | 1.8 | 1.47 |
| Yerry de los Santos | NYA | mr | 27 | 12 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 8.4 | 2.6 | 11.4 | 6.3 | 1.3 | 2.4 | 1.22 |
| Jacob deGrom | | sp | 37 | 43 | 6 | 0 | 3 | 4 | 1 | 0 | 1 | 7.5 | 2.3 | 10.0 | 12.0 | 1.0 | 5.1 | 1.09 |
| Reid Detmers* | | sp | 25 | 3 | 4 | 0 | 1 | 2 | 0 | 0 | 1 | 9.8 | 4.6 | 14.6 | 8.6 | 0.9 | 1.9 | 1.60 |
| Alexis Diaz | Det | cl | 28 | 7 | 2 | 0 | 5 | 6 | 0 | 0 | 1 | 6.6 | 5.1 | 12.2 | 8.5 | 0.3 | 1.7 | 1.30 |
| Edwin Diaz | LAA | cl | 31 | 8 | 0 | 0 | 2 | 7 | 0 | 0 | 1 | 8.0 | 3.5 | 11.7 | 14.5 | 1.3 | 4.1 | 1.28 |
| Miguel Diaz | | mr | 30 | 10 | 4 | 0 | 4 | 4 | 0 | 1 | 0 | 7.9 | 2.6 | 11.0 | 8.0 | 0.6 | 3.0 | 1.17 |
| Yilber Diaz | Hou | sp | 24 | 25 | 3 | 2 | 7 | 20 | 2 | 2 | 4 | 7.5 | 4.3 | 12.3 | 7.1 | 1.0 | 1.7 | 1.31 |
| Hunter Dobbins | Sea | sp | 25 | 4 | 2 | 0 | 2 | 1 | 0 | 1 | 0 | 7.3 | 4.5 | 12.9 | 7.9 | 0.0 | 1.8 | 1.31 |
| Dylan Dodd* | Sac | sp | 27 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 11.4 | 3.1 | 14.5 | 9.3 | 2.1 | 3.0 | 1.62 |
| Chase Dollander | Ari | sp | 23 | 12 | 0 | 0 | 8 | 4 | 0 | 0 | 1 | 8.9 | 4.5 | 14.7 | 8.2 | 0.5 | 1.8 | 1.49 |
| Seranthony Dominguez | Was | mr | 30 | 23 | 3 | 1 | 6 | 7 | 0 | 0 | 4 | 6.7 | 4.3 | 11.7 | 9.6 | 1.3 | 2.3 | 1.22 |
| Camilo Doval | Cle | cl | 27 | 4 | 3 | 1 | 3 | 3 | 0 | 0 | 3 | 6.7 | 3.4 | 10.6 | 11.9 | 0.6 | 3.5 | 1.13 |
| Jack Dreyer* | KC | mr | 26 | 18 | 5 | 4 | 1 | 6 | 0 | 1 | 1 | 7.6 | 3.2 | 10.9 | 10.6 | 0.8 | 3.3 | 1.20 |
| Jhoan Duran | Sea | cl | 27 | 8 | 3 | 0 | 5 | 9 | 0 | 0 | 2 | 5.7 | 2.6 | 8.8 | 11.5 | 0.7 | 4.5 | 0.92 |
| Zach Eflin | | sp | 31 | 17 | 8 | 0 | 4 | 0 | 0 | 0 | 2 | 10.3 | 2.2 | 12.8 | 7.5 | 0.9 | 3.4 | 1.39 |
| Brandon Eisert* | Det | mr | 27 | 10 | 4 | 0 | 0 | 3 | 3 | 0 | 5 | 11.0 | 4.1 | 15.1 | 8.5 | 0.7 | 2.1 | 1.68 |
| Bryce Elder | NYN | sp | 26 | 39 | 15 | 0 | 7 | 10 | 2 | 0 | 8 | 7.3 | 3.9 | 11.5 | 6.3 | 0.9 | 1.6 | 1.24 |
| Magnus Ellerts | Atl | mr | 24 | 8 | 3 | 2 | 3 | 17 | 1 | 0 | 2 | 10.6 | 4.7 | 15.7 | 10.3 | 1.4 | 2.2 | 1.70 |
| Mason Englert | Atl | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 0.0 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Nic Enright | Cin | mr | 28 | 9 | 6 | 1 | 4 | 0 | 1 | 0 | 1 | 9.7 | 3.1 | 13.3 | 8.4 | 0.7 | 2.7 | 1.43 |
| Nathan Eovaldi | Sac | sp | 35 | 3 | 4 | 0 | 4 | 0 | 0 | 0 | 2 | 6.8 | 1.8 | 9.1 | 8.2 | 0.3 | 4.5 | 0.96 |
| Lucas Erceg | LAN | mr | 30 | 0 | 5 | 2 | 6 | 9 | 2 | 0 | 1 | 7.3 | 2.7 | 10.6 | 9.8 | 1.2 | 3.7 | 1.10 |
| Carlos Estevez | | cl | 32 | 15 | 3 | 2 | 2 | 11 | 0 | 0 | 2 | 7.4 | 3.1 | 10.8 | 9.8 | 1.4 | 3.1 | 1.17 |
| Jeremiah Estrada | Sea | mr | 26 | 15 | 5 | 2 | 5 | 5 | 0 | 1 | 2 | 7.7 | 4.5 | 12.8 | 12.0 | 0.9 | 2.7 | 1.36 |
| Logan Evans | Tor | sp | 24 | 2 | 3 | 1 | 4 | 6 | 1 | 0 | 2 | 8.5 | 4.9 | 14.2 | 6.5 | 0.6 | 1.3 | 1.49 |
| Pete Fairbanks | ChN | cl | 31 | 6 | 1 | 0 | 2 | 3 | 0 | 0 | 0 | 7.0 | 3.9 | 11.2 | 9.2 | 1.1 | 2.4 | 1.21 |
| Bailey Falter* | KC | sp | 28 | 15 | 4 | 0 | 2 | 0 | 0 | 0 | 3 | 9.9 | 2.5 | 12.5 | 6.8 | 0.9 | 2.8 | 1.37 |
| Calvin Faucher | | mr | 29 | 14 | 2 | 1 | 7 | 3 | 0 | 1 | 4 | 9.9 | 4.6 | 15.4 | 8.6 | 0.5 | 1.9 | 1.61 |
| Erick Fedde | Tam | sp | 32 | 13 | 2 | 0 | 1 | 2 | 0 | 0 | 0 | 10.3 | 4.6 | 15.0 | 9.7 | 1.1 | 2.1 | 1.65 |
| Ryan Feltner | Mil | sp | 28 | 7 | 2 | 0 | 0 | 1 | 0 | 0 | 2 | 7.5 | 2.5 | 10.0 | 7.5 | 1.5 | 3.0 | 1.11 |
| Caleb Ferguson* | LAA | mr | 28 | 5 | 2 | 0 | 4 | 3 | 1 | 0 | 1 | 9.2 | 2.9 | 12.7 | 7.9 | 1.1 | 2.7 | 1.34 |
| Ryan Fernandez | | mr | 27 | 17 | 1 | 1 | 1 | 0 | 1 | 0 | 3 | 9.4 | 4.0 | 13.6 | 9.4 | 1.8 | 2.3 | 1.49 |
| Jose A. Ferrer* | Hou | mr | 25 | 12 | 2 | 2 | 3 | 4 | 0 | 0 | 1 | 7.9 | 2.3 | 10.4 | 8.4 | 0.6 | 3.7 | 1.13 |
| David Festa | Hou | sp | 25 | 24 | 3 | 0 | 3 | 5 | 0 | 0 | 1 | 10.3 | 4.5 | 15.2 | 9.6 | 1.0 | 2.1 | 1.65 |
| Kyle Finnegan | NYN | cl | 33 | 14 | 0 | 0 | 6 | 1 | 1 | 1 | 0 | 7.7 | 3.2 | 11.9 | 9.4 | 1.7 | 2.9 | 1.22 |
| Braydon Fisher | LAN | mr | 24 | 15 | 6 | 0 | 3 | 15 | 0 | 1 | 8 | 9.1 | 5.2 | 14.6 | 8.0 | 1.1 | 1.5 | 1.59 |
| Jack Flaherty | | sp | 29 | 19 | 6 | 1 | 9 | 3 | 0 | 1 | 5 | 7.4 | 2.7 | 10.6 | 10.7 | 1.3 | 4.0 | 1.12 |
| Jose Fleury | StL | sp | 23 | 32 | 5 | 4 | 3 | 10 | 1 | 0 | 6 | 9.3 | 4.3 | 13.8 | 7.6 | 1.5 | 1.8 | 1.51 |
| Dylan Floro | Was | mr | 34 | 9 | 1 | 0 | 3 | 3 | 0 | 0 | 1 | 7.7 | 2.2 | 10.3 | 7.9 | 0.3 | 3.6 | 1.10 |
| Mason Fluharty* | | mr | 23 | 15 | 2 | 0 | 3 | 4 | 0 | 0 | 7 | 7.8 | 3.4 | 11.5 | 8.5 | 1.2 | 2.5 | 1.25 |
| Jason Foley | Sac | cl | 29 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 1 | 8.6 | 6.1 | 14.7 | 13.5 | 0.0 | 2.2 | 1.64 |
| J.P. France | KC | sp | 30 | 4 | 5 | 0 | 1 | 1 | 0 | 0 | 1 | 8.1 | 4.0 | 12.4 | 6.8 | 1.3 | 1.7 | 1.35 |
| Bowden Francis | Tex | sp | 29 | 7 | 1 | 0 | 5 | 2 | 1 | 0 | 4 | 6.5 | 0.9 | 8.0 | 8.1 | 1.1 | 8.9 | 0.83 |
| Max Fried* | Ari | sp | 31 | 32 | 12 | 1 | 8 | 5 | 0 | 0 | 8 | 8.5 | 2.8 | 11.6 | 7.9 | 0.6 | 2.8 | 1.25 |
| Kody Funderburk* | | mr | 28 | 10 | 2 | 1 | 6 | 0 | 0 | 0 | 2 | 10.1 | 4.1 | 15.7 | 7.7 | 1.0 | 1.9 | 1.58 |
| Hunter Gaddis | Bos | mr | 27 | 13 | 5 | 1 | 10 | 0 | 2 | 0 | 4 | 7.9 | 2.4 | 10.9 | 8.8 | 1.3 | 3.7 | 1.14 |
| Matt Gage* | NYA | mr | 32 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 13.5 | 7.4 | 20.9 | 7.4 | 0.0 | 1.0 | 2.32 |
| Zac Gallen | Mia | sp | 29 | 34 | 13 | 0 | 14 | 5 | 2 | 1 | 7 | 7.5 | 3.3 | 11.3 | 8.5 | 0.8 | 2.6 | 1.19 |
| Brandyn Garcia* | Bal | sp | 25 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 27.0 | 54.0 | 0.0 | 0.0 | 0.0 | 6.00 |
| Luis A. Garcia | | mr | 38 | 10 | 2 | 4 | 1 | 10 | 0 | 1 | 7 | 11.3 | 3.1 | 14.5 | 8.3 | 0.4 | 2.7 | 1.60 |
| Robert Garcia* | Was | mr | 29 | 2 | 1 | 2 | 1 | 8 | 0 | 0 | 0 | 6.3 | 3.1 | 9.6 | 11.3 | 0.5 | 3.7 | 1.05 |
| Yimi Garcia | Hou | mr | 34 | 2 | 1 | 0 | 0 | 0 | 0 | 2 | 1 | 7.1 | 3.4 | 10.5 | 8.3 | 1.9 | 2.4 | 1.17 |
| Reed Garrett | NYN | mr | 32 | 5 | 3 | 0 | 2 | 6 | 1 | 0 | 1 | 6.9 | 4.4 | 11.6 | 11.9 | 0.4 | 2.7 | 1.27 |
| Robert Gasser* | Cin | sp | 26 | 5 | 0 | 0 | 4 | 1 | 0 | 0 | 4 | 7.3 | 3.8 | 12.4 | 8.6 | 0.3 | 2.3 | 1.24 |
| Kevin Gausman | Min | sp | 34 | 28 | 8 | 0 | 5 | 2 | 0 | 0 | 5 | 8.4 | 2.2 | 10.9 | 8.3 | 1.3 | 3.7 | 1.19 |
| Paul Gervase | | mr | 25 | 14 | 4 | 1 | 2 | 16 | 1 | 0 | 3 | 7.6 | 5.8 | 13.7 | 9.6 | 0.8 | 1.6 | 1.49 |
| Kyle Gibson | Bos | sp | 37 | 3 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 8.0 | 4.2 | 12.4 | 6.8 | 1.4 | 1.6 | 1.36 |
| Luis Gil | SD | sp | 27 | 9 | 3 | 0 | 1 | 2 | 0 | 0 | 3 | 6.6 | 4.3 | 11.1 | 10.9 | 1.4 | 2.5 | 1.21 |
| Logan Gilbert | Ari | sp | 28 | 20 | 4 | 0 | 4 | 5 | 0 | 0 | 8 | 9.1 | 2.3 | 11.7 | 10.1 | 0.8 | 4.4 | 1.27 |
| Kevin Ginkel | | mr | 31 | 4 | 1 | 1 | 1 | 7 | 0 | 0 | 1 | 6.8 | 3.5 | 10.4 | 9.1 | 0.2 | 2.6 | 1.14 |
| J.T. Ginn | | sp | 26 | 16 | 4 | 2 | 4 | 5 | 0 | 0 | 2 | 9.7 | 4.1 | 14.4 | 6.9 | 0.7 | 1.7 | 1.53 |
| Lucas Giolito | Mia | sp | 30 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 9.3 | 3.9 | 13.3 | 9.3 | 1.0 | 2.4 | 1.47 |
| Sawyer Gipson-Long | Mia | sp | 27 | 9 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 10.6 | 2.9 | 13.8 | 10.3 | 2.3 | 3.6 | 1.50 |
| Tyler Glasnow | Sea | sp | 31 | 27 | 9 | 0 | 2 | 5 | 0 | 0 | 3 | 8.1 | 3.2 | 11.4 | 10.5 | 1.1 | 3.3 | 1.25 |
| Yoendrys Gomez | SD | sp | 25 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.3 | 6.0 | 11.3 | 9.8 | 0.8 | 1.6 | 1.25 |
| Tony Gonsolin | Tex | sp | 31 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 7.2 | 2.1 | 9.5 | 7.4 | 1.2 | 3.6 | 1.03 |
| Colton Gordon* | | sp | 26 | 40 | 3 | 0 | 3 | 1 | 2 | 2 | 5 | 7.7 | 3.1 | 11.1 | 8.5 | 1.1 | 2.8 | 1.20 |
| MacKenzie Gore* | | sp | 26 | 26 | 5 | 0 | 2 | 2 | 0 | 1 | 4 | 7.9 | 3.7 | 11.8 | 9.1 | 1.1 | 2.5 | 1.29 |
| Gordon Graceffo | Min | sp | 25 | 5 | 3 | 3 | 0 | 1 | 0 | 2 | 1 | 10.2 | 4.8 | 15.0 | 7.9 | 1.0 | 1.6 | 1.67 |
| Andre Granillo | NYA | mr | 25 | 17 | 1 | 5 | 0 | 10 | 0 | 0 | 5 | 10.9 | 6.7 | 17.6 | 8.5 | 2.4 | 1.3 | 1.96 |
| Kendall Graveman | NYN | mr | 34 | 5 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 6.0 | 5.2 | 11.5 | 8.7 | 2.0 | 1.7 | 1.24 |
| Jon Gray | Sac | sp | 33 | 5 | 4 | 0 | 3 | 0 | 1 | 0 | 1 | 5.3 | 2.4 | 8.5 | 9.3 | 0.3 | 3.9 | 0.85 |
| Sonny Gray | Phi | sp | 35 | 27 | 12 | 0 | 10 | 1 | 1 | 0 | 2 | 6.0 | 2.6 | 9.0 | 9.6 | 1.2 | 3.7 | 0.95 |
| Chad Green | ChN | mr | 34 | 7 | 6 | 0 | 1 | 1 | 0 | 0 | 3 | 9.6 | 2.3 | 12.0 | 8.2 | 1.7 | 3.6 | 1.31 |
| Hunter Greene | Col | sp | 25 | 8 | 4 | 0 | 4 | 0 | 0 | 0 | 2 | 7.2 | 3.7 | 11.5 | 9.8 | 1.0 | 2.7 | 1.22 |
| Sean Guenther* | Bal | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 20.3 | 6.8 | 27.0 | 0.0 | 0.0 | 0.0 | 3.00 |
| Luis Guerrero | | mr | 24 | 11 | 1 | 0 | 5 | 1 | 1 | 1 | 1 | 6.3 | 6.5 | 13.6 | 9.4 | 1.0 | 1.5 | 1.42 |
| Ryan Gusto | | sp | 26 | 6 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 11.5 | 5.0 | 17.3 | 6.5 | 1.4 | 1.3 | 1.84 |
| Josh Hader* | | cl | 31 | 4 | 2 | 3 | 1 | 3 | 1 | 1 | 1 | 7.7 | 5.1 | 13.1 | 13.9 | 1.8 | 2.7 | 1.43 |
| Skylar Hales | Atl | mr | 23 | 5 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 9.6 | 3.6 | 13.3 | 9.9 | 1.5 | 2.8 | 1.46 |
| DL Hall* | Bal | sp | 26 | 1 | 2 | 0 | 1 | 0 | 2 | 0 | 1 | 7.1 | 4.9 | 12.3 | 11.5 | 0.3 | 2.3 | 1.33 |
| Seth Halvorsen | Hou | mr | 25 | 5 | 6 | 0 | 3 | 3 | 1 | 0 | 2 | 6.6 | 4.2 | 11.3 | 8.3 | 0.9 | 2.0 | 1.20 |
| Ian Hamilton | Tex | mr | 30 | 13 | 8 | 0 | 4 | 6 | 0 | 0 | 4 | 7.8 | 4.1 | 12.3 | 10.1 | 0.5 | 2.4 | 1.33 |
| Emerson Hancock | Sea | sp | 26 | 7 | 4 | 0 | 0 | 1 | 0 | 0 | 1 | 8.7 | 6.0 | 14.7 | 5.2 | 0.0 | 0.9 | 1.63 |
| Brenan Hanifee | Det | mr | 27 | 22 | 3 | 0 | 7 | 2 | 0 | 0 | 4 | 8.0 | 2.6 | 10.8 | 7.2 | 1.1 | 2.8 | 1.17 |
| Landon Harper | Cin | mr | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 7.4 | 0.6 | 8.0 | 3.7 | 0.0 | 6.0 | 0.89 |
| Thomas Harrington | Sea | sp | 23 | 26 | 6 | 0 | 6 | 1 | 1 | 1 | 1 | 8.1 | 3.5 | 12.0 | 7.2 | 1.4 | 2.0 | 1.29 |
| Hayden Harris* | Cle | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 81.0 | 27.0 | 108.0 | 27.0 | 13.5 | 1.0 | 12.00 |
| Kyle Harrison* | | sp | 23 | 23 | 10 | 0 | 7 | 2 | 3 | 0 | 3 | 8.1 | 3.1 | 11.7 | 8.3 | 0.9 | 2.6 | 1.25 |
| Kyle Hart* | Mil | sp | 32 | 23 | 11 | 2 | 9 | 2 | 1 | 0 | 4 | 8.4 | 2.4 | 11.3 | 8.0 | 0.9 | 3.3 | 1.21 |
| Grant Hartwig | NYN | mr | 27 | 4 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 7.6 | 7.6 | 16.9 | 11.8 | 0.8 | 1.6 | 1.69 |
| Hunter Harvey | Hou | mr | 30 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 7.1 | 3.3 | 10.4 | 7.9 | 0.4 | 2.4 | 1.15 |
| Brent Headrick* | NYA | sp | 27 | 5 | 2 | 0 | 2 | 0 | 0 | 0 | 1 | 10.5 | 2.4 | 13.4 | 9.7 | 1.9 | 4.0 | 1.43 |
| Andrew Heaney* | StL | sp | 34 | 29 | 4 | 1 | 8 | 0 | 0 | 2 | 4 | 8.8 | 3.9 | 13.3 | 9.3 | 1.7 | 2.4 | 1.41 |
| Ryan Helsley | Col | cl | 30 | 3 | 1 | 0 | 2 | 3 | 1 | 2 | 0 | 8.1 | 4.2 | 12.5 | 12.8 | 0.7 | 3.1 | 1.36 |
| Logan Henderson | SF | sp | 23 | 27 | 4 | 0 | 11 | 6 | 0 | 0 | 9 | 8.6 | 2.9 | 12.2 | 9.5 | 1.5 | 3.3 | 1.28 |
| Liam Hendriks | ChN | cl | 36 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.6 | 7.7 | 17.4 | 13.5 | 0.0 | 1.8 | 1.93 |
| Edgardo Henriquez | Atl | mr | 23 | 4 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 9.7 | 6.7 | 16.7 | 10.0 | 0.6 | 1.5 | 1.82 |
| Ronny Henriquez | Tex | mr | 25 | 9 | 1 | 0 | 6 | 3 | 3 | 0 | 1 | 10.6 | 4.2 | 15.8 | 7.7 | 1.7 | 1.8 | 1.64 |
| Cole Henry | Tor | sp | 25 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 6.8 | 6.4 | 14.2 | 8.4 | 0.7 | 1.3 | 1.46 |
| Tommy Henry* | LAA | sp | 27 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.6 | 5.3 | 15.9 | 7.2 | 1.4 | 1.4 | 1.77 |
| Carlos Hernandez | ChN | mr | 28 | 37 | 8 | 0 | 10 | 7 | 0 | 1 | 5 | 7.1 | 4.0 | 11.6 | 8.7 | 0.8 | 2.2 | 1.24 |
| Daysbel Hernandez | | mr | 28 | 8 | 5 | 0 | 3 | 5 | 1 | 2 | 3 | 9.1 | 5.7 | 15.3 | 9.9 | 1.1 | 1.8 | 1.64 |
| Tim Herrin* | | mr | 28 | 11 | 2 | 5 | 3 | 13 | 0 | 1 | 1 | 9.3 | 5.4 | 15.0 | 9.7 | 0.6 | 1.8 | 1.63 |
| Jordan Hicks | SF | mr | 28 | 13 | 6 | 0 | 4 | 12 | 0 | 0 | 3 | 9.3 | 5.9 | 15.6 | 8.9 | 1.1 | 1.5 | 1.69 |
| Jaden Hill | | mr | 25 | 9 | 2 | 0 | 8 | 4 | 0 | 0 | 3 | 9.3 | 4.9 | 15.9 | 8.2 | 2.0 | 1.7 | 1.57 |
| Sean Hjelle | SF | mr | 28 | 17 | 2 | 3 | 8 | 6 | 0 | 0 | 3 | 9.2 | 3.4 | 13.3 | 7.1 | 0.8 | 2.1 | 1.40 |
| Porter Hodge | Was | mr | 24 | 2 | 4 | 0 | 2 | 7 | 1 | 0 | 0 | 8.6 | 5.1 | 14.1 | 8.6 | 1.4 | 1.7 | 1.53 |
| Bryan Hoeing | | mr | 28 | 23 | 6 | 1 | 3 | 7 | 1 | 0 | 4 | 8.2 | 2.7 | 11.1 | 7.3 | 0.9 | 2.7 | 1.22 |
| Jeff Hoffman | Min | mr | 32 | 7 | 1 | 0 | 5 | 2 | 0 | 0 | 3 | 6.6 | 3.2 | 10.4 | 11.4 | 1.4 | 3.5 | 1.09 |
| Andrew Hoffmann | Hou | sp | 25 | 26 | 3 | 0 | 2 | 1 | 2 | 0 | 4 | 8.7 | 3.7 | 12.7 | 6.5 | 1.2 | 1.7 | 1.39 |
| Gunnar Hoglund | Sac | sp | 25 | 6 | 3 | 1 | 0 | 2 | 0 | 0 | 1 | 11.5 | 4.4 | 15.9 | 5.3 | 2.2 | 1.2 | 1.77 |
| Colin Holderman | Bal | mr | 29 | 21 | 3 | 0 | 3 | 3 | 0 | 1 | 1 | 9.2 | 5.0 | 14.5 | 8.4 | 1.4 | 1.7 | 1.58 |
| Grant Holman | KC | mr | 25 | 5 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 7.4 | 2.0 | 9.4 | 6.7 | 0.4 | 3.4 | 1.04 |
| Clay Holmes | Sac | sp | 32 | 16 | 3 | 2 | 4 | 10 | 0 | 1 | 9 | 10.1 | 2.9 | 13.2 | 6.9 | 0.8 | 2.4 | 1.45 |
| Grant Holmes | Mia | mr | 29 | 2 | 3 | 0 | 5 | 3 | 0 | 0 | 2 | 7.5 | 2.9 | 11.2 | 7.7 | 0.5 | 2.7 | 1.16 |
| Tyler Holton* | Cle | mr | 29 | 7 | 7 | 0 | 5 | 0 | 0 | 0 | 3 | 7.0 | 2.5 | 9.9 | 7.6 | 1.0 | 3.1 | 1.05 |
| Cade Horton | Tam | sp | 23 | 27 | 4 | 0 | 8 | 7 | 0 | 0 | 3 | 8.2 | 2.4 | 11.4 | 8.6 | 1.1 | 3.6 | 1.18 |
| Tanner Houck | LAN | sp | 29 | 13 | 4 | 0 | 7 | 0 | 1 | 0 | 2 | 7.8 | 3.6 | 12.1 | 7.2 | 0.9 | 2.0 | 1.26 |
| Adrian Houser | StL | sp | 32 | 8 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 9.1 | 4.9 | 14.0 | 5.8 | 1.6 | 1.2 | 1.55 |
| Bryan Hudson* | Col | mr | 28 | 11 | 3 | 1 | 1 | 1 | 0 | 0 | 1 | 7.7 | 3.4 | 11.3 | 9.7 | 0.6 | 2.8 | 1.24 |
| Brandon Hughes* | NYN | mr | 29 | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 5.5 | 3.6 | 9.8 | 12.0 | 1.0 | 3.4 | 1.01 |
| K.C. Hunt | Bos | sp | 24 | 32 | 5 | 0 | 1 | 10 | 2 | 0 | 4 | 7.0 | 4.2 | 11.3 | 8.9 | 0.7 | 2.1 | 1.25 |
| Brant Hurter* | ChN | sp | 26 | 26 | 11 | 3 | 12 | 2 | 0 | 1 | 3 | 9.2 | 2.5 | 12.3 | 6.5 | 1.0 | 2.5 | 1.30 |
| Raisel Iglesias | | cl | 35 | 6 | 2 | 4 | 3 | 1 | 0 | 0 | 3 | 7.1 | 2.1 | 9.5 | 10.2 | 1.4 | 4.9 | 1.02 |
| Shota Imanaga* | Col | sp | 31 | 11 | 8 | 0 | 7 | 2 | 1 | 0 | 0 | 9.5 | 2.1 | 12.0 | 7.9 | 1.0 | 3.7 | 1.29 |
| Jairo Iriarte | Col | sp | 23 | 4 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 7.5 | 3.2 | 11.2 | 6.9 | 0.9 | 2.2 | 1.18 |
| Cole Irvin* | | sp | 31 | 4 | 1 | 1 | 6 | 1 | 0 | 1 | 9 | 7.9 | 2.9 | 11.4 | 6.5 | 0.8 | 2.3 | 1.20 |
| Jake Irvin | | sp | 28 | 5 | 6 | 0 | 3 | 6 | 0 | 0 | 3 | 9.8 | 3.4 | 13.6 | 6.4 | 1.2 | 1.9 | 1.47 |
| Luke Jackson | Bal | mr | 33 | 9 | 2 | 0 | 3 | 5 | 2 | 1 | 2 | 7.9 | 4.7 | 13.0 | 9.9 | 1.2 | 2.1 | 1.41 |
| Alek Jacob | Pit | mr | 27 | 5 | 3 | 0 | 4 | 1 | 0 | 0 | 3 | 7.9 | 4.0 | 12.3 | 8.0 | 0.7 | 2.0 | 1.32 |
| Drey Jameson | Was | sp | 27 | 27 | 7 | 1 | 10 | 5 | 0 | 0 | 5 | 7.9 | 2.6 | 11.0 | 7.9 | 1.0 | 3.1 | 1.17 |
| Kenley Jansen | Tam | cl | 37 | 17 | 0 | 0 | 4 | 9 | 1 | 0 | 9 | 5.9 | 3.8 | 10.1 | 10.6 | 0.5 | 2.8 | 1.07 |
| Cristian Javier | Min | sp | 28 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 8.9 | 3.8 | 12.7 | 7.2 | 0.8 | 1.9 | 1.41 |
| Griffin Jax | Mia | mr | 30 | 5 | 0 | 1 | 2 | 4 | 2 | 1 | 1 | 7.7 | 2.6 | 10.6 | 9.8 | 0.3 | 3.8 | 1.14 |
| Jackson Jobe | SF | sp | 22 | 23 | 8 | 1 | 7 | 0 | 0 | 0 | 3 | 9.1 | 2.6 | 12.5 | 8.0 | 1.5 | 3.0 | 1.30 |
| Pierce Johnson | Mil | mr | 34 | 7 | 4 | 1 | 8 | 6 | 0 | 1 | 1 | 7.7 | 4.1 | 12.7 | 10.3 | 1.2 | 2.5 | 1.31 |
| Seth Johnson | StL | sp | 26 | 6 | 2 | 0 | 2 | 4 | 0 | 0 | 3 | 7.9 | 6.7 | 15.2 | 6.1 | 1.2 | 0.9 | 1.62 |
| Ben Joyce | Sac | mr | 24 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 7.1 | 4.3 | 11.4 | 14.2 | 0.0 | 3.3 | 1.26 |
| Jakob Junis | Det | mr | 32 | 5 | 1 | 1 | 2 | 3 | 0 | 0 | 1 | 8.4 | 2.2 | 11.1 | 8.0 | 0.7 | 3.6 | 1.18 |
| Janson Junk | Tex | sp | 29 | 6 | 0 | 3 | 1 | 1 | 0 | 0 | 1 | 8.1 | 4.6 | 12.9 | 5.8 | 1.6 | 1.3 | 1.41 |
| Tommy Kahnle | | mr | 35 | 3 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 7.7 | 5.5 | 13.2 | 10.4 | 0.9 | 1.9 | 1.47 |
| James Karinchak | Min | mr | 29 | 3 | 2 | 0 | 5 | 6 | 0 | 0 | 1 | 8.1 | 4.8 | 14.8 | 8.1 | 0.4 | 1.7 | 1.44 |
| Mitch Keller | KC | sp | 29 | 40 | 12 | 0 | 20 | 0 | 0 | 2 | 7 | 7.4 | 2.7 | 11.0 | 7.7 | 0.8 | 2.8 | 1.13 |
| Kevin Kelly | | mr | 27 | 6 | 0 | 1 | 4 | 0 | 0 | 1 | 3 | 6.6 | 2.3 | 9.5 | 8.0 | 1.0 | 3.4 | 0.99 |
| Merrill Kelly | Det | sp | 36 | 19 | 5 | 0 | 2 | 0 | 0 | 0 | 2 | 9.0 | 3.6 | 12.8 | 7.3 | 1.9 | 2.0 | 1.40 |
| Zak Kent | KC | sp | 27 | 13 | 4 | 2 | 1 | 4 | 0 | 0 | 4 | 8.8 | 2.7 | 11.6 | 8.8 | 1.5 | 3.3 | 1.27 |
| Orion Kerkering | Bos | mr | 24 | 6 | 5 | 0 | 5 | 0 | 0 | 0 | 1 | 5.6 | 2.9 | 9.2 | 8.9 | 0.0 | 3.1 | 0.95 |
| Clayton Kershaw* | LAA | sp | 37 | 20 | 3 | 0 | 3 | 6 | 2 | 0 | 1 | 7.9 | 2.2 | 10.2 | 8.1 | 1.0 | 3.7 | 1.11 |
| Yusei Kikuchi* | NYN | sp | 34 | 25 | 6 | 0 | 4 | 6 | 0 | 1 | 2 | 7.5 | 2.4 | 10.1 | 11.2 | 0.9 | 4.7 | 1.10 |
| Craig Kimbrel | Cle | cl | 37 | 8 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 6.9 | 4.2 | 11.6 | 12.4 | 0.5 | 2.9 | 1.24 |
| Bryan King* | Tam | mr | 28 | 7 | 1 | 0 | 2 | 3 | 0 | 1 | 5 | 6.9 | 4.2 | 11.4 | 8.3 | 0.5 | 2.0 | 1.24 |
| John King* | KC | mr | 30 | 4 | 2 | 14 | 3 | 3 | 1 | 1 | 2 | 8.4 | 3.8 | 12.6 | 6.0 | 0.7 | 1.6 | 1.36 |
| Michael King | Tam | sp | 30 | 10 | 5 | 0 | 3 | 0 | 0 | 0 | 1 | 5.3 | 2.6 | 8.2 | 10.4 | 0.7 | 4.0 | 0.88 |
| George Kirby | Sea | sp | 27 | 32 | 11 | 0 | 7 | 2 | 0 | 0 | 3 | 8.3 | 2.2 | 11.0 | 8.3 | 0.8 | 3.8 | 1.17 |
| Andrew Kittredge | ChN | mr | 35 | 11 | 4 | 2 | 1 | 0 | 0 | 0 | 1 | 9.0 | 2.2 | 11.4 | 7.1 | 1.0 | 3.2 | 1.25 |
| George Klassen | Bos | sp | 23 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 10.8 | 5.4 | 16.2 | 5.4 | 1.8 | 1.0 | 1.80 |
| Jack Kochanowicz | StL | sp | 24 | 18 | 4 | 1 | 9 | 3 | 1 | 0 | 5 | 9.9 | 2.5 | 13.3 | 4.5 | 0.7 | 1.8 | 1.38 |
| Jared Koenig* | Tam | mr | 31 | 3 | 0 | 4 | 1 | 2 | 0 | 0 | 2 | 11.8 | 5.1 | 17.1 | 8.1 | 0.5 | 1.6 | 1.88 |
| Stephen Kolek | | mr | 28 | 7 | 1 | 0 | 4 | 3 | 0 | 0 | 1 | 9.5 | 3.5 | 13.7 | 7.6 | 0.5 | 2.2 | 1.45 |
| Michael Kopech | SF | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.0 | 0.0 | 3.0 | 12.0 | 0.0 | 99.0 | 0.33 |
| Dean Kremer | Det | sp | 29 | 21 | 10 | 0 | 11 | 5 | 0 | 0 | 3 | 8.6 | 3.8 | 13.1 | 7.2 | 1.1 | 1.9 | 1.38 |
| Ben Kudrna | | sp | 22 | 1 | 2 | 0 | 1 | 1 | 0 | 0 | 1 | 13.0 | 4.0 | 18.0 | 8.0 | 3.0 | 2.0 | 1.89 |
| Alex Lange | LAN | mr | 29 | 25 | 6 | 0 | 5 | 10 | 0 | 0 | 2 | 7.7 | 6.6 | 14.8 | 8.8 | 1.0 | 1.3 | 1.59 |
| Sauryn Lao | Sac | mr | 25 | 16 | 0 | 0 | 1 | 2 | 0 | 1 | 5 | 9.1 | 3.7 | 12.9 | 8.0 | 1.7 | 2.2 | 1.42 |
| Andry Lara | LAN | sp | 22 | 58 | 7 | 2 | 2 | 8 | 1 | 1 | 3 | 9.6 | 4.3 | 14.0 | 6.2 | 0.6 | 1.4 | 1.54 |
| Jhancarlos Lara | StL | sp | 22 | 1 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 10.1 | 7.9 | 18.6 | 8.4 | 1.1 | 1.1 | 2.00 |
| Jake Latz* | NYA | mr | 29 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.2 | 3.2 | 6.4 | 7.9 | 1.6 | 2.5 | 0.71 |
| Eric Lauer* | Tex | sp | 30 | 6 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 9.9 | 2.6 | 12.8 | 8.1 | 0.4 | 3.1 | 1.40 |
| Max Lazar | Phi | mr | 26 | 8 | 3 | 1 | 3 | 3 | 0 | 0 | 4 | 7.7 | 2.9 | 10.9 | 7.3 | 1.1 | 2.5 | 1.17 |
| Kyle Leahy | ChN | mr | 28 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.2 | 4.7 | 15.8 | 6.5 | 1.2 | 1.4 | 1.76 |
| Jordan Leasure | Sac | mr | 26 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 6.0 | 9.0 | 15.0 | 10.5 | 3.0 | 1.2 | 1.67 |
| Jose Leclerc | Pit | mr | 31 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 4.4 | 5.2 | 10.9 | 10.9 | 0.0 | 2.1 | 1.07 |
| Chase Lee | | mr | 26 | 5 | 1 | 0 | 1 | 1 | 0 | 0 | 2 | 10.7 | 3.7 | 14.6 | 10.0 | 1.8 | 2.7 | 1.60 |
| Dylan Lee* | Det | mr | 30 | 6 | 1 | 2 | 3 | 1 | 0 | 1 | 2 | 9.5 | 2.8 | 12.6 | 11.8 | 1.4 | 4.2 | 1.36 |
| Jack Leiter | SF | sp | 25 | 9 | 2 | 0 | 2 | 3 | 0 | 0 | 1 | 8.2 | 4.1 | 12.9 | 9.7 | 1.2 | 2.4 | 1.37 |
| Mark Jr. Leiter | | mr | 34 | 3 | 1 | 0 | 2 | 3 | 1 | 0 | 2 | 6.5 | 4.2 | 11.2 | 11.4 | 1.9 | 2.7 | 1.20 |
| Matthew Liberatore* | Cin | mr | 25 | 3 | 4 | 0 | 5 | 8 | 0 | 0 | 6 | 10.1 | 3.9 | 14.6 | 6.4 | 1.4 | 1.6 | 1.56 |
| Zack Littell | | sp | 29 | 5 | 5 | 0 | 7 | 4 | 1 | 0 | 4 | 10.4 | 2.0 | 13.0 | 7.6 | 1.3 | 3.8 | 1.38 |
| Brendon Little* | LAN | mr | 28 | 14 | 4 | 9 | 4 | 18 | 1 | 1 | 5 | 8.2 | 6.1 | 14.8 | 7.6 | 0.6 | 1.2 | 1.59 |
| Luke Little* | Col | mr | 24 | 13 | 1 | 1 | 7 | 0 | 0 | 0 | 0 | 7.6 | 4.0 | 12.6 | 9.8 | 0.9 | 2.4 | 1.29 |
| Ben Lively | Col | sp | 33 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 3.6 | 14.4 | 3.6 | 3.6 | 1.0 | 1.40 |
| Jonathan Loaisiga | Ari | mr | 30 | 3 | 1 | 1 | 4 | 1 | 0 | 1 | 1 | 9.4 | 2.7 | 13.0 | 8.8 | 0.2 | 3.3 | 1.35 |
| Ryan Lobus | ChA | mr | 24 | 5 | 1 | 0 | 3 | 2 | 0 | 0 | 1 | 8.1 | 3.3 | 12.0 | 8.3 | 2.2 | 2.5 | 1.26 |
| Nick Lodolo* | | sp | 27 | 28 | 7 | 0 | 18 | 1 | 0 | 0 | 6 | 7.8 | 3.9 | 12.9 | 10.0 | 1.2 | 2.5 | 1.30 |
| Jacob Lopez* | Tex | sp | 27 | 3 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 6.8 | 3.1 | 10.3 | 9.0 | 1.8 | 2.9 | 1.10 |
| Pablo Lopez | Tex | sp | 29 | 6 | 3 | 0 | 6 | 3 | 0 | 0 | 3 | 6.9 | 2.6 | 10.1 | 10.9 | 0.9 | 4.2 | 1.06 |
| Brad Lord | Sac | sp | 25 | 5 | 1 | 0 | 3 | 0 | 0 | 0 | 1 | 7.9 | 3.7 | 12.4 | 6.6 | 0.3 | 1.8 | 1.29 |
| Michael Lorenzen | | sp | 33 | 14 | 7 | 0 | 4 | 2 | 1 | 0 | 1 | 8.6 | 4.8 | 13.7 | 6.2 | 1.6 | 1.3 | 1.49 |
| Richard Lovelady* | ChN | mr | 29 | 17 | 6 | 2 | 9 | 0 | 0 | 1 | 1 | 7.9 | 1.9 | 10.4 | 7.9 | 0.4 | 4.1 | 1.10 |
| Seth Lugo | NYN | sp | 35 | 20 | 11 | 0 | 6 | 1 | 0 | 1 | 6 | 7.8 | 2.7 | 10.8 | 8.5 | 1.1 | 3.2 | 1.16 |
| Jesus Luzardo* | Tex | sp | 27 | 7 | 4 | 1 | 4 | 2 | 1 | 0 | 4 | 7.3 | 3.6 | 11.3 | 9.7 | 0.6 | 2.7 | 1.21 |
| Daniel Lynch* | Phi | sp | 28 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.5 | 4.5 | 9.0 | 5.6 | 0.0 | 1.3 | 1.00 |
| Tyler Mahle | Ari | sp | 30 | 8 | 2 | 0 | 1 | 1 | 0 | 0 | 1 | 6.8 | 3.2 | 10.1 | 8.6 | 0.5 | 2.7 | 1.11 |
| Alek Manoah | Sea | sp | 27 | 3 | 2 | 1 | 5 | 0 | 0 | 0 | 0 | 8.6 | 3.8 | 15.1 | 7.0 | 0.5 | 1.9 | 1.38 |
| Joe Mantiply* | Col | mr | 34 | 1 | 3 | 3 | 2 | 2 | 0 | 0 | 1 | 6.0 | 2.4 | 8.7 | 8.9 | 0.8 | 3.8 | 0.93 |
| Ron Marinaccio | ChA | mr | 29 | 25 | 4 | 0 | 7 | 9 | 1 | 0 | 2 | 7.4 | 6.4 | 14.4 | 9.6 | 1.0 | 1.5 | 1.53 |
| German Marquez | | sp | 30 | 10 | 2 | 0 | 3 | 4 | 1 | 0 | 1 | 7.8 | 3.0 | 11.0 | 7.3 | 0.5 | 2.5 | 1.19 |
| Yunior Marte | StL | sp | 21 | 2 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 9.6 | 5.8 | 16.2 | 5.8 | 2.1 | 1.0 | 1.71 |
| Chris Martin | ChN | mr | 39 | 13 | 2 | 1 | 0 | 4 | 0 | 1 | 0 | 8.4 | 1.3 | 9.7 | 9.9 | 0.3 | 7.6 | 1.08 |
| Davis Martin | SD | sp | 28 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 6.5 | 3.7 | 11.2 | 9.3 | 0.0 | 2.5 | 1.14 |
| Riley Martin* | NYA | mr | 27 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 8.8 | 4.1 | 13.5 | 8.2 | 0.6 | 2.0 | 1.43 |
| Justin Martinez | Tex | mr | 23 | 3 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 7.2 | 4.0 | 11.5 | 12.6 | 0.0 | 3.2 | 1.24 |
| Nick Martinez | Mil | mr | 34 | 38 | 13 | 0 | 10 | 5 | 0 | 0 | 6 | 8.6 | 2.3 | 11.3 | 8.4 | 0.5 | 3.7 | 1.20 |
| Quinn Mathews* | StL | sp | 24 | 31 | 5 | 1 | 7 | 4 | 0 | 1 | 2 | 8.4 | 4.3 | 13.2 | 9.1 | 0.6 | 2.1 | 1.41 |
| Phil Maton | NYN | mr | 32 | 4 | 2 | 0 | 5 | 0 | 0 | 0 | 0 | 7.2 | 2.2 | 10.4 | 9.4 | 0.6 | 4.3 | 1.05 |
| Yuki Matsui* | NYN | mr | 29 | 3 | 4 | 0 | 2 | 3 | 1 | 0 | 1 | 10.5 | 8.3 | 19.5 | 9.8 | 2.6 | 1.2 | 2.08 |
| Zebby Matthews | Was | sp | 25 | 1 | 3 | 0 | 0 | 2 | 0 | 0 | 3 | 7.3 | 1.0 | 8.3 | 8.9 | 1.0 | 9.3 | 0.92 |
| Isaac Mattson | Ari | mr | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 12.0 | 7.0 | 19.0 | 8.0 | 1.0 | 1.1 | 2.11 |
| Steven Matz* | LAA | sp | 34 | 20 | 0 | 1 | 11 | 5 | 0 | 2 | 5 | 7.0 | 3.4 | 11.1 | 7.8 | 0.7 | 2.3 | 1.16 |
| Zach Maxwell | | mr | 24 | 3 | 1 | 0 | 0 | 6 | 0 | 0 | 5 | 7.3 | 6.6 | 13.9 | 9.4 | 1.0 | 1.4 | 1.54 |
| Dustin May | Was | sp | 27 | 43 | 15 | 0 | 16 | 2 | 0 | 0 | 8 | 5.9 | 3.5 | 10.1 | 8.7 | 0.8 | 2.5 | 1.04 |
| Adam Mazur | Tam | sp | 24 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 6.4 | 2.0 | 8.4 | 4.8 | 0.5 | 2.3 | 0.93 |
| Lance McCullers | Tex | sp | 31 | 11 | 7 | 0 | 2 | 4 | 0 | 1 | 0 | 7.7 | 4.7 | 12.7 | 7.7 | 0.7 | 1.6 | 1.38 |
| Chayce McDermott | LAN | sp | 26 | 40 | 11 | 0 | 6 | 6 | 0 | 1 | 6 | 7.5 | 4.7 | 12.5 | 9.2 | 1.6 | 2.0 | 1.36 |
| Griff McGarry | Bal | mr | 26 | 5 | 1 | 0 | 1 | 3 | 0 | 0 | 4 | 6.7 | 7.9 | 14.9 | 6.1 | 0.9 | 0.8 | 1.62 |
| Easton McGee | | sp | 27 | 1 | 0 | 1 | 3 | 2 | 0 | 0 | 2 | 12.4 | 2.2 | 15.7 | 7.7 | 1.5 | 3.5 | 1.62 |
| Michael McGreevy | ChA | sp | 24 | 32 | 5 | 4 | 6 | 7 | 1 | 1 | 1 | 10.6 | 3.2 | 14.1 | 7.4 | 1.2 | 2.3 | 1.53 |
| Nolan McLean | Atl | dh | 23 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 10.0 | 7.0 | 17.0 | 7.0 | 0.0 | 1.0 | 1.89 |
| Nick Mears | Phi | mr | 28 | 4 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 7.7 | 5.2 | 12.9 | 11.6 | 1.5 | 2.2 | 1.43 |
| Trevor Megill | | cl | 31 | 2 | 0 | 2 | 1 | 2 | 0 | 0 | 4 | 7.4 | 4.3 | 11.9 | 10.8 | 0.4 | 2.5 | 1.30 |
| Tylor Megill | NYN | sp | 29 | 6 | 1 | 1 | 1 | 0 | 0 | 0 | 2 | 9.5 | 5.4 | 15.2 | 8.6 | 2.5 | 1.6 | 1.66 |
| Cristian Mena | SD | sp | 22 | 26 | 8 | 0 | 2 | 4 | 2 | 0 | 2 | 8.9 | 5.4 | 14.5 | 7.3 | 1.1 | 1.4 | 1.59 |
| Julian Merryweather | | mr | 33 | 7 | 1 | 1 | 1 | 3 | 0 | 0 | 2 | 7.1 | 5.0 | 12.3 | 9.8 | 0.6 | 2.0 | 1.35 |
| Luis Mey | Phi | mr | 24 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 20.3 | 6.8 | 27.0 | 6.8 | 6.8 | 1.0 | 3.00 |
| Max Meyer | ChA | sp | 26 | 30 | 8 | 0 | 6 | 4 | 0 | 0 | 2 | 8.0 | 3.8 | 12.1 | 8.0 | 0.8 | 2.1 | 1.31 |
| Miles Mikolas | | sp | 36 | 9 | 3 | 0 | 2 | 0 | 0 | 0 | 2 | 12.3 | 2.4 | 14.8 | 6.5 | 2.1 | 2.8 | 1.63 |
| Bobby Miller | Bal | sp | 26 | 16 | 3 | 0 | 6 | 3 | 0 | 0 | 2 | 7.6 | 3.7 | 11.7 | 8.1 | 0.8 | 2.2 | 1.25 |
| Bryce Miller | | sp | 26 | 9 | 5 | 0 | 3 | 3 | 0 | 0 | 3 | 9.1 | 2.0 | 11.5 | 8.7 | 1.2 | 4.2 | 1.24 |
| Erik Miller* | Tor | mr | 27 | 9 | 3 | 0 | 1 | 1 | 0 | 0 | 3 | 10.2 | 5.5 | 15.8 | 10.2 | 1.1 | 1.8 | 1.74 |
| Jacob Miller | StL | sp | 21 | 11 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 12.3 | 4.6 | 17.4 | 6.2 | 1.2 | 1.3 | 1.89 |
| Mason Miller | Bos | cl | 26 | 11 | 4 | 0 | 4 | 7 | 0 | 0 | 3 | 7.5 | 3.5 | 11.5 | 11.4 | 0.7 | 3.2 | 1.23 |
| Shelby Miller | | mr | 34 | 5 | 2 | 0 | 4 | 0 | 0 | 0 | 2 | 6.7 | 3.5 | 10.8 | 8.2 | 1.5 | 2.3 | 1.13 |
| Tyson Miller | Mil | mr | 29 | 6 | 0 | 2 | 2 | 1 | 0 | 0 | 1 | 7.4 | 3.6 | 11.5 | 6.8 | 1.1 | 1.9 | 1.22 |
| Hoby Milner* | | mr | 34 | 4 | 1 | 2 | 5 | 1 | 0 | 0 | 0 | 9.0 | 1.9 | 11.6 | 6.8 | 0.7 | 3.6 | 1.20 |
| Camden Minacci | Cin | mr | 23 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 10.0 | 3.0 | 13.0 | 11.0 | 2.0 | 3.7 | 1.44 |
| A.J. Minter* | Was | mr | 31 | 4 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 7.0 | 6.2 | 13.5 | 13.0 | 0.5 | 2.1 | 1.47 |
| Andrew Misiaszek* | | mr | 27 | 3 | 3 | 1 | 1 | 0 | 0 | 0 | 1 | 8.8 | 6.3 | 15.4 | 7.7 | 1.8 | 1.2 | 1.68 |
| Jacob Misiorowski | Tex | sp | 23 | 2 | 1 | 0 | 8 | 4 | 0 | 0 | 1 | 8.1 | 9.0 | 20.7 | 9.4 | 1.8 | 1.0 | 1.90 |
| Casey Mize | KC | sp | 28 | 16 | 6 | 0 | 1 | 0 | 1 | 0 | 1 | 8.3 | 4.2 | 12.6 | 6.9 | 0.4 | 1.7 | 1.39 |
| Carmen Mlodzinski | KC | mr | 26 | 17 | 2 | 0 | 11 | 7 | 0 | 1 | 3 | 9.2 | 3.1 | 13.4 | 7.7 | 0.9 | 2.5 | 1.37 |
| Keider Montero | | sp | 24 | 10 | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 11.7 | 4.3 | 16.5 | 6.2 | 1.7 | 1.4 | 1.78 |
| Mason Montgomery* | | sp | 25 | 12 | 3 | 0 | 3 | 4 | 0 | 0 | 5 | 7.9 | 3.4 | 11.6 | 8.2 | 1.0 | 2.4 | 1.25 |
| Michael Morales | StL | sp | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.6 | 3.9 | 15.4 | 7.7 | 3.9 | 2.0 | 1.71 |
| Adrian Morejon* | Cle | mr | 26 | 12 | 1 | 1 | 2 | 6 | 0 | 0 | 2 | 8.6 | 4.4 | 13.2 | 9.6 | 0.5 | 2.2 | 1.44 |
| Dauri Moreta | Mil | mr | 29 | 1 | 2 | 1 | 1 | 3 | 0 | 0 | 3 | 10.8 | 4.0 | 15.3 | 6.3 | 1.8 | 1.6 | 1.65 |
| David Morgan | Col | mr | 25 | 5 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 11.4 | 1.4 | 12.8 | 8.5 | 0.0 | 6.0 | 1.42 |
| Eli Morgan | Det | mr | 29 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.2 | 3.0 | 13.2 | 8.2 | 1.6 | 2.8 | 1.46 |
| Andrew Morris | Cin | sp | 23 | 8 | 2 | 0 | 1 | 1 | 0 | 0 | 1 | 8.4 | 0.8 | 9.4 | 5.4 | 1.6 | 6.7 | 1.02 |
| Charlie Morton | | sp | 41 | 40 | 13 | 1 | 20 | 2 | 0 | 2 | 9 | 6.7 | 4.2 | 11.9 | 10.0 | 0.8 | 2.4 | 1.22 |
| Andres Munoz | Sea | cl | 26 | 15 | 1 | 1 | 4 | 5 | 0 | 0 | 0 | 6.7 | 3.1 | 10.1 | 11.8 | 0.9 | 3.9 | 1.08 |
| Penn Murfee | Pit | mr | 31 | 7 | 1 | 0 | 2 | 2 | 0 | 0 | 4 | 7.6 | 3.6 | 11.7 | 5.6 | 1.0 | 1.6 | 1.25 |
| Tobias Myers | Min | sp | 26 | 10 | 3 | 1 | 1 | 6 | 0 | 0 | 5 | 8.5 | 2.6 | 11.1 | 8.3 | 1.1 | 3.2 | 1.23 |
| Jack Neely | Hou | mr | 25 | 13 | 4 | 6 | 2 | 7 | 1 | 0 | 2 | 7.4 | 3.1 | 10.7 | 8.6 | 0.4 | 2.8 | 1.16 |
| Kyle Nelson* | Atl | mr | 28 | 5 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 6.6 | 3.1 | 9.7 | 7.8 | 1.2 | 2.5 | 1.08 |
| Ryne Nelson | Cin | sp | 27 | 18 | 13 | 0 | 3 | 12 | 3 | 0 | 7 | 10.1 | 3.0 | 13.2 | 6.7 | 1.6 | 2.3 | 1.45 |
| Kyle Nicolas | Atl | mr | 26 | 11 | 4 | 1 | 6 | 4 | 0 | 0 | 5 | 9.2 | 4.0 | 13.8 | 9.5 | 1.0 | 2.4 | 1.47 |
| Doug Nikhazy* | Was | sp | 25 | 1 | 0 | 0 | 1 | 3 | 0 | 0 | 1 | 5.2 | 3.5 | 9.1 | 10.9 | 1.3 | 3.1 | 0.97 |
| Aaron Nola | Min | sp | 32 | 7 | 5 | 0 | 2 | 1 | 0 | 0 | 3 | 7.5 | 2.0 | 9.8 | 8.3 | 0.9 | 4.0 | 1.07 |
| Dedniel Nunez | Tex | mr | 29 | 6 | 2 | 1 | 0 | 2 | 0 | 0 | 3 | 9.2 | 3.9 | 13.0 | 10.4 | 1.1 | 2.7 | 1.45 |
| Juan Nunez | Phi | sp | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 0.0 | 13.5 | 13.5 | 6.8 | 99.0 | 1.50 |
| Riley O'Brien | ChA | mr | 30 | 19 | 8 | 0 | 3 | 4 | 0 | 1 | 3 | 8.6 | 5.0 | 13.9 | 8.9 | 1.3 | 1.8 | 1.51 |
| Bailey Ober | Phi | sp | 29 | 26 | 3 | 0 | 7 | 0 | 1 | 0 | 7 | 7.3 | 2.1 | 9.8 | 9.2 | 1.2 | 4.3 | 1.05 |
| Shohei Ohtani | Tex | dh | 30 | 11 | 5 | 0 | 7 | 6 | 1 | 0 | 8 | 6.8 | 4.0 | 11.5 | 9.8 | 2.1 | 2.5 | 1.20 |
| Steven Okert* | Bos | mr | 33 | 9 | 3 | 1 | 5 | 0 | 2 | 0 | 4 | 6.6 | 4.4 | 12.0 | 8.9 | 0.8 | 2.0 | 1.22 |
| Reese Olson | KC | sp | 25 | 16 | 0 | 0 | 3 | 1 | 0 | 0 | 2 | 6.6 | 3.0 | 9.9 | 9.0 | 0.4 | 3.0 | 1.07 |
| Oliver Ortega | Bal | mr | 28 | 19 | 5 | 0 | 3 | 11 | 0 | 0 | 4 | 8.1 | 3.5 | 11.8 | 9.6 | 0.6 | 2.8 | 1.29 |
| Luis L. Ortiz | SD | sp | 26 | 11 | 7 | 0 | 4 | 3 | 3 | 0 | 1 | 7.4 | 3.6 | 11.5 | 8.7 | 0.9 | 2.4 | 1.23 |
| Eric Orze | | mr | 27 | 4 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 10.4 | 3.1 | 14.1 | 7.3 | 0.6 | 2.4 | 1.50 |
| Johan Oviedo | Cle | sp | 27 | 10 | 4 | 0 | 2 | 2 | 2 | 0 | 0 | 6.9 | 3.6 | 11.1 | 8.7 | 0.3 | 2.4 | 1.17 |
| Chris Paddack | LAA | sp | 29 | 19 | 8 | 0 | 4 | 3 | 1 | 0 | 5 | 7.6 | 2.1 | 9.9 | 8.6 | 0.8 | 4.1 | 1.08 |
| Emilio Pagan | ChA | mr | 34 | 18 | 0 | 1 | 3 | 2 | 0 | 2 | 2 | 8.9 | 2.7 | 12.0 | 8.6 | 1.4 | 3.1 | 1.30 |
| Andrew Painter | Atl | sp | 22 | 5 | 4 | 0 | 0 | 2 | 0 | 0 | 2 | 8.3 | 3.1 | 11.4 | 9.6 | 1.1 | 3.1 | 1.27 |
| Daniel Palencia | Sea | mr | 25 | 12 | 5 | 0 | 3 | 6 | 2 | 0 | 3 | 7.4 | 5.3 | 13.0 | 9.9 | 1.1 | 1.9 | 1.41 |
| Andre Pallante | Min | sp | 26 | 22 | 3 | 0 | 3 | 9 | 2 | 0 | 3 | 9.1 | 4.0 | 13.3 | 5.9 | 0.8 | 1.5 | 1.45 |
| Peyton Pallette | SD | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.4 | 0.0 | 6.4 | 15.9 | 0.0 | 99.0 | 0.71 |
| Mitchell Parker* | Atl | sp | 25 | 8 | 2 | 1 | 0 | 11 | 1 | 2 | 1 | 9.0 | 3.5 | 12.5 | 9.8 | 1.0 | 2.8 | 1.39 |
| Joel Payamps | | mr | 31 | 4 | 4 | 0 | 2 | 0 | 0 | 0 | 2 | 6.7 | 2.6 | 9.5 | 9.1 | 0.7 | 3.5 | 1.03 |
| Nate Pearson | Hou | mr | 28 | 12 | 1 | 0 | 2 | 2 | 1 | 0 | 1 | 7.3 | 5.2 | 13.1 | 11.5 | 2.1 | 2.2 | 1.40 |
| Ethan Pecko | Hou | sp | 22 | 19 | 2 | 1 | 1 | 5 | 0 | 0 | 3 | 9.8 | 3.7 | 13.6 | 7.0 | 0.4 | 1.9 | 1.50 |
| Elvis Peguero | Det | mr | 28 | 15 | 2 | 2 | 8 | 6 | 0 | 1 | 5 | 10.0 | 3.8 | 14.6 | 6.7 | 0.9 | 1.8 | 1.53 |
| Walter Pennington* | NYA | mr | 27 | 5 | 2 | 1 | 1 | 0 | 0 | 0 | 1 | 6.5 | 4.2 | 11.1 | 8.1 | 0.0 | 1.9 | 1.19 |
| Ryan Pepiot | KC | sp | 27 | 30 | 7 | 1 | 12 | 4 | 0 | 0 | 6 | 8.0 | 3.5 | 12.2 | 9.7 | 1.0 | 2.8 | 1.28 |
| Freddy Peralta | Mia | sp | 29 | 27 | 17 | 0 | 5 | 11 | 0 | 0 | 9 | 7.4 | 4.2 | 11.8 | 9.6 | 1.0 | 2.3 | 1.29 |
| Wandy Peralta* | SD | mr | 33 | 3 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 7.2 | 5.7 | 13.7 | 8.4 | 1.1 | 1.5 | 1.44 |
| Angel Perdomo* | Mia | mr | 31 | 9 | 3 | 1 | 2 | 4 | 1 | 0 | 0 | 5.1 | 4.5 | 9.9 | 12.8 | 1.2 | 2.9 | 1.06 |
| Cionel Perez* | | mr | 29 | 4 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 8.8 | 4.2 | 12.9 | 6.9 | 1.2 | 1.7 | 1.44 |
| Eury Perez | Bal | sp | 22 | 24 | 6 | 0 | 2 | 4 | 0 | 0 | 2 | 8.1 | 4.1 | 12.4 | 8.7 | 1.5 | 2.1 | 1.36 |
| Martin Perez* | LAN | sp | 34 | 4 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 7.8 | 2.8 | 11.0 | 6.4 | 0.4 | 2.3 | 1.18 |
| Jack Perkins | ChA | sp | 25 | 10 | 4 | 1 | 3 | 2 | 0 | 0 | 4 | 8.1 | 3.5 | 12.2 | 7.2 | 1.8 | 2.1 | 1.29 |
| David Peterson* | Sac | sp | 29 | 8 | 4 | 4 | 6 | 5 | 0 | 0 | 3 | 8.1 | 3.5 | 12.0 | 7.9 | 0.9 | 2.3 | 1.29 |
| Chase Petty | ChA | sp | 22 | 4 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 10.3 | 4.3 | 14.8 | 8.0 | 1.9 | 1.9 | 1.63 |
| Brandon Pfaadt | Col | sp | 26 | 17 | 5 | 1 | 7 | 5 | 2 | 0 | 3 | 8.6 | 2.9 | 11.9 | 9.5 | 1.8 | 3.3 | 1.28 |
| Evan Phillips | Mil | cl | 30 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.6 | 4.3 | 13.0 | 8.6 | 0.0 | 2.0 | 1.44 |
| Tyler Phillips | Cle | sp | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 5.4 | 18.9 | 5.4 | 0.0 | 1.0 | 2.10 |
| Nick Pivetta | Cle | sp | 32 | 22 | 6 | 1 | 3 | 3 | 1 | 0 | 5 | 10.3 | 3.4 | 13.9 | 10.8 | 1.1 | 3.2 | 1.52 |
| Drew Pomeranz* | Was | mr | 36 | 12 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | 7.7 | 4.8 | 12.7 | 8.9 | 1.0 | 1.8 | 1.39 |
| Cody Poteet | NYN | sp | 30 | 7 | 2 | 0 | 2 | 1 | 0 | 0 | 2 | 6.0 | 2.8 | 9.3 | 7.1 | 0.8 | 2.5 | 0.99 |
| Cade Povich* | Bos | sp | 25 | 16 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 8.8 | 3.9 | 13.1 | 9.2 | 1.6 | 2.3 | 1.42 |
| Ryan Pressly | | mr | 36 | 3 | 5 | 0 | 3 | 1 | 0 | 0 | 2 | 8.3 | 2.4 | 11.3 | 8.3 | 0.9 | 3.5 | 1.19 |
| Quinn Priester | Ari | sp | 24 | 25 | 7 | 0 | 9 | 6 | 0 | 0 | 4 | 7.5 | 2.9 | 10.9 | 7.9 | 0.5 | 2.7 | 1.16 |
| A.J. Puk* | LAN | mr | 30 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6.1 | 4.9 | 11.0 | 14.7 | 1.2 | 3.0 | 1.23 |
| Jose Quijada* | | mr | 29 | 8 | 1 | 0 | 1 | 0 | 1 | 1 | 3 | 8.6 | 5.5 | 14.4 | 10.7 | 0.3 | 1.9 | 1.57 |
| Jose Quintana* | Pit | sp | 36 | 20 | 2 | 1 | 4 | 2 | 1 | 0 | 6 | 10.9 | 3.6 | 15.0 | 6.8 | 0.6 | 1.9 | 1.62 |
| Cole Ragans* | Was | sp | 27 | 11 | 9 | 0 | 3 | 3 | 0 | 0 | 2 | 7.2 | 3.1 | 10.6 | 8.5 | 0.7 | 2.7 | 1.15 |
| Brooks Raley* | Mia | mr | 37 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 6.6 | 3.3 | 9.9 | 9.9 | 0.7 | 3.0 | 1.10 |
| Drew Rasmussen | Bos | sp | 29 | 22 | 7 | 0 | 9 | 5 | 1 | 0 | 3 | 7.6 | 2.5 | 10.5 | 9.7 | 0.7 | 3.9 | 1.12 |
| Dylan Ray | StL | sp | 24 | 42 | 4 | 1 | 5 | 8 | 0 | 0 | 2 | 10.9 | 4.4 | 15.7 | 7.8 | 1.2 | 1.8 | 1.70 |
| Robbie Ray* | Pit | sp | 33 | 48 | 9 | 1 | 6 | 3 | 3 | 2 | 5 | 7.0 | 3.8 | 11.1 | 9.1 | 1.3 | 2.4 | 1.20 |
| Sean Reid-Foley | Atl | mr | 29 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 14.6 | 7.3 | 21.9 | 10.9 | 1.5 | 1.5 | 2.43 |
| Patrick Reilly | StL | sp | 23 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.3 | 4.3 | 8.6 | 8.3 | 0.6 | 1.9 | 0.95 |
| Eric Reyzelman | | mr | 24 | 6 | 1 | 0 | 3 | 4 | 0 | 0 | 2 | 8.8 | 3.1 | 12.7 | 9.9 | 1.8 | 3.2 | 1.33 |
| Trevor Richards | NYN | mr | 32 | 13 | 2 | 0 | 3 | 6 | 0 | 0 | 1 | 5.5 | 4.1 | 9.9 | 10.1 | 1.2 | 2.5 | 1.06 |
| Lyon Richardson | NYA | sp | 25 | 5 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 8.2 | 3.9 | 13.3 | 12.5 | 2.0 | 3.2 | 1.35 |
| Ethan Roberts | Sac | mr | 27 | 7 | 5 | 0 | 9 | 4 | 0 | 0 | 3 | 8.7 | 2.5 | 12.3 | 8.3 | 1.3 | 3.3 | 1.25 |
| David Robertson | Mil | mr | 40 | 2 | 1 | 0 | 0 | 3 | 0 | 0 | 1 | 5.6 | 2.8 | 8.4 | 9.5 | 0.7 | 3.4 | 0.94 |
| Tekoah Roby | Sac | sp | 23 | 4 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 17.5 | 2.4 | 20.6 | 7.9 | 1.6 | 3.3 | 2.21 |
| Joe Rock* | Cle | sp | 24 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 10.1 | 3.6 | 13.9 | 9.2 | 1.5 | 2.6 | 1.52 |
| Kumar Rocker | SD | sp | 25 | 24 | 2 | 0 | 1 | 4 | 0 | 0 | 3 | 8.1 | 2.4 | 10.6 | 9.8 | 1.2 | 4.0 | 1.17 |
| Carlos Rodon* | | sp | 32 | 22 | 11 | 0 | 5 | 7 | 1 | 0 | 4 | 8.3 | 2.8 | 11.4 | 10.7 | 1.0 | 3.8 | 1.23 |
| Carlos F. Rodriguez | | sp | 23 | 9 | 4 | 0 | 3 | 2 | 1 | 0 | 1 | 8.3 | 3.4 | 11.9 | 8.0 | 1.3 | 2.4 | 1.29 |
| Eduardo Rodriguez* | Min | sp | 32 | 11 | 8 | 1 | 0 | 0 | 0 | 1 | 2 | 9.1 | 2.9 | 11.9 | 8.3 | 1.1 | 2.9 | 1.33 |
| Manuel Rodriguez | Pit | mr | 28 | 5 | 3 | 0 | 3 | 2 | 1 | 0 | 0 | 11.8 | 3.7 | 16.3 | 6.8 | 0.8 | 1.8 | 1.72 |
| Randy Rodriguez | Hou | mr | 25 | 18 | 3 | 4 | 10 | 2 | 1 | 1 | 2 | 6.8 | 3.6 | 11.2 | 8.3 | 0.7 | 2.3 | 1.15 |
| Wilking Rodriguez | Det | mr | 35 | 2 | 1 | 0 | 1 | 2 | 0 | 0 | 3 | 9.8 | 4.3 | 14.4 | 8.6 | 1.1 | 2.0 | 1.56 |
| Yariel Rodriguez | ChN | sp | 28 | 6 | 3 | 0 | 7 | 0 | 1 | 0 | 0 | 6.2 | 4.9 | 12.5 | 9.6 | 0.6 | 2.0 | 1.24 |
| Taylor Rogers* | Ari | mr | 34 | 12 | 3 | 2 | 8 | 1 | 1 | 1 | 3 | 8.3 | 4.8 | 14.0 | 10.1 | 0.7 | 2.1 | 1.46 |
| Trevor Rogers* | SF | sp | 27 | 5 | 2 | 0 | 2 | 0 | 0 | 0 | 1 | 6.7 | 3.7 | 10.7 | 9.8 | 0.9 | 2.6 | 1.16 |
| Tyler Rogers | Cle | mr | 34 | 3 | 2 | 2 | 4 | 0 | 1 | 0 | 0 | 8.5 | 2.3 | 11.4 | 7.8 | 0.7 | 3.4 | 1.20 |
| Drew Rom* | Bos | sp | 25 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 14.5 | 2.1 | 16.6 | 6.2 | 0.0 | 3.0 | 1.85 |
| Jordan Romano | | cl | 32 | 14 | 4 | 2 | 2 | 1 | 0 | 0 | 3 | 8.5 | 3.2 | 11.9 | 12.1 | 0.5 | 3.7 | 1.30 |
| JoJo Romero* | Min | mr | 28 | 4 | 3 | 2 | 11 | 3 | 0 | 1 | 0 | 8.7 | 3.3 | 13.3 | 8.6 | 1.7 | 2.6 | 1.33 |
| Landen Roupp | | mr | 26 | 34 | 5 | 0 | 3 | 2 | 5 | 0 | 2 | 7.9 | 4.5 | 12.6 | 7.2 | 0.9 | 1.6 | 1.37 |
| Joe Ryan | Min | sp | 29 | 24 | 7 | 0 | 9 | 3 | 2 | 1 | 5 | 8.6 | 3.0 | 12.1 | 8.9 | 1.5 | 3.0 | 1.29 |
| Andrew Saalfrank* | Mia | mr | 27 | 9 | 2 | 0 | 0 | 3 | 0 | 0 | 1 | 6.3 | 5.4 | 11.6 | 8.8 | 0.9 | 1.6 | 1.29 |
| Erik Sabrowski* | Pit | mr | 27 | 1 | 1 | 0 | 0 | 3 | 0 | 1 | 0 | 8.6 | 2.9 | 11.5 | 13.2 | 1.1 | 4.6 | 1.28 |
| Chris Sale* | LAA | sp | 36 | 15 | 6 | 0 | 7 | 2 | 0 | 0 | 3 | 7.5 | 2.1 | 10.1 | 11.3 | 0.9 | 5.4 | 1.07 |
| Cristopher Sanchez* | Tam | sp | 28 | 36 | 6 | 1 | 8 | 5 | 0 | 0 | 9 | 8.6 | 2.5 | 11.5 | 7.8 | 0.9 | 3.1 | 1.24 |
| Nick Sandlin | Col | mr | 28 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.0 | 1.8 | 7.8 | 10.2 | 1.2 | 5.7 | 0.87 |
| Cole Sands | | mr | 27 | 17 | 6 | 0 | 6 | 7 | 4 | 0 | 5 | 6.2 | 3.2 | 9.8 | 10.4 | 0.9 | 3.3 | 1.04 |
| Dennis Santana | Bal | mr | 29 | 13 | 1 | 1 | 3 | 5 | 3 | 0 | 4 | 7.7 | 3.8 | 11.7 | 8.4 | 0.7 | 2.2 | 1.27 |
| Tony Santillan | Col | mr | 28 | 0 | 0 | 0 | 2 | 4 | 0 | 0 | 1 | 6.5 | 3.3 | 10.2 | 10.7 | 1.1 | 3.3 | 1.09 |
| Gregory Santos | LAA | mr | 25 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 8.2 | 3.5 | 14.1 | 8.2 | 1.2 | 2.3 | 1.30 |
| Roki Sasaki | Col | sp | 23 | 14 | 4 | 0 | 2 | 2 | 0 | 0 | 0 | 10.3 | 2.5 | 13.1 | 10.1 | 1.8 | 4.0 | 1.42 |
| Tayler Saucedo* | Mil | mr | 32 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 10.3 | 4.8 | 15.1 | 8.7 | 1.2 | 1.8 | 1.68 |
| Max Scherzer | Cle | sp | 40 | 6 | 3 | 0 | 6 | 1 | 0 | 0 | 1 | 6.5 | 2.6 | 9.6 | 9.7 | 0.8 | 3.8 | 1.01 |
| Cam Schlittler | | sp | 24 | 18 | 1 | 0 | 1 | 2 | 0 | 0 | 1 | 7.9 | 4.5 | 12.6 | 7.6 | 1.0 | 1.7 | 1.37 |
| Clarke Schmidt | | sp | 29 | 22 | 4 | 0 | 4 | 4 | 0 | 0 | 3 | 8.4 | 4.1 | 12.9 | 8.8 | 1.0 | 2.1 | 1.39 |
| John Schreiber | | mr | 31 | 1 | 2 | 0 | 1 | 1 | 0 | 1 | 1 | 7.0 | 3.3 | 10.5 | 7.8 | 0.9 | 2.4 | 1.14 |
| Noah Schultz* | ChA | sp | 21 | 25 | 2 | 0 | 7 | 3 | 2 | 0 | 2 | 8.1 | 3.2 | 12.0 | 7.1 | 1.0 | 2.2 | 1.26 |
| Spencer Schwellenbach | Atl | sp | 25 | 12 | 3 | 0 | 6 | 2 | 0 | 0 | 4 | 8.4 | 2.8 | 11.8 | 8.8 | 1.2 | 3.1 | 1.25 |
| Christian Scott | NYA | sp | 26 | 10 | 2 | 0 | 5 | 0 | 1 | 0 | 2 | 7.1 | 3.6 | 11.8 | 9.5 | 0.9 | 2.7 | 1.18 |
| Tanner Scott* | NYN | cl | 30 | 6 | 4 | 4 | 2 | 3 | 0 | 0 | 1 | 5.8 | 3.5 | 9.5 | 11.4 | 0.7 | 3.2 | 1.03 |
| Tayler Scott | Phi | mr | 33 | 7 | 0 | 0 | 1 | 5 | 0 | 0 | 1 | 9.3 | 3.0 | 12.6 | 10.5 | 1.2 | 3.5 | 1.37 |
| JP Sears* | Cin | sp | 29 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 12.0 | 0.0 | 12.0 | 12.0 | 3.0 | 99.0 | 1.33 |
| Kodai Senga | | sp | 32 | 17 | 9 | 0 | 4 | 5 | 1 | 0 | 6 | 7.1 | 4.6 | 11.9 | 10.6 | 1.7 | 2.3 | 1.30 |
| Luis Severino | Tex | sp | 31 | 6 | 1 | 0 | 7 | 1 | 1 | 1 | 3 | 10.4 | 2.9 | 14.0 | 7.3 | 1.6 | 2.5 | 1.48 |
| Paul Sewald | Cle | cl | 35 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.3 | 1.7 | 8.0 | 9.2 | 1.1 | 5.3 | 0.89 |
| Carson Seymour | | sp | 26 | 10 | 4 | 0 | 1 | 3 | 0 | 0 | 2 | 8.9 | 3.5 | 12.7 | 8.1 | 1.3 | 2.3 | 1.38 |
| Emmet Sheehan | Ari | sp | 25 | 12 | 6 | 0 | 4 | 1 | 0 | 1 | 3 | 6.6 | 3.8 | 10.8 | 9.7 | 0.7 | 2.6 | 1.15 |
| Brady Singer | LAN | sp | 28 | 32 | 13 | 1 | 10 | 1 | 1 | 0 | 5 | 7.6 | 3.2 | 11.3 | 7.9 | 0.8 | 2.4 | 1.21 |
| Paul Skenes | SF | sp | 23 | 25 | 9 | 0 | 2 | 2 | 1 | 0 | 2 | 9.6 | 3.0 | 12.7 | 10.3 | 1.3 | 3.4 | 1.40 |
| Tarik Skubal* | Tam | sp | 28 | 40 | 7 | 0 | 6 | 4 | 2 | 0 | 6 | 7.3 | 1.6 | 9.1 | 10.8 | 0.9 | 6.6 | 0.99 |
| Justin Slaten | Det | mr | 27 | 13 | 0 | 0 | 2 | 4 | 0 | 0 | 2 | 6.8 | 2.5 | 9.6 | 10.2 | 0.9 | 4.0 | 1.04 |
| Ethan Small* | NYN | mr | 28 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 2.3 | 15.8 | 13.5 | 4.5 | 6.0 | 1.75 |
| Cade Smith | LAA | mr | 26 | 10 | 3 | 1 | 5 | 3 | 0 | 0 | 3 | 7.0 | 3.2 | 10.8 | 12.5 | 0.3 | 3.9 | 1.14 |
| Shane Smith | SD | mr | 25 | 14 | 3 | 0 | 5 | 1 | 1 | 1 | 1 | 7.4 | 2.4 | 10.6 | 9.3 | 0.7 | 3.9 | 1.09 |
| AJ Smith-Shawver | Tex | sp | 22 | 8 | 0 | 0 | 1 | 1 | 0 | 0 | 3 | 8.6 | 3.4 | 12.4 | 9.2 | 1.7 | 2.7 | 1.34 |
| Blake Snell* | | sp | 32 | 14 | 2 | 0 | 3 | 4 | 0 | 0 | 1 | 6.5 | 4.1 | 10.9 | 11.9 | 1.0 | 2.9 | 1.17 |
| Robby Snelling* | Bal | sp | 21 | 25 | 6 | 0 | 6 | 1 | 1 | 1 | 4 | 9.1 | 4.0 | 13.6 | 6.8 | 0.9 | 1.7 | 1.46 |
| Anthony Solometo* | StL | sp | 22 | 4 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 6.0 | 4.0 | 10.5 | 7.0 | 0.5 | 1.8 | 1.11 |
| Jose Soriano | Cin | mr | 26 | 22 | 6 | 0 | 12 | 15 | 0 | 0 | 5 | 7.9 | 3.7 | 12.2 | 9.0 | 0.8 | 2.4 | 1.28 |
| Mike Soroka | Ari | sp | 27 | 6 | 2 | 1 | 3 | 2 | 1 | 0 | 1 | 9.3 | 5.2 | 15.0 | 7.9 | 1.9 | 1.5 | 1.61 |
| Gregory Soto* | Tam | mr | 30 | 4 | 3 | 1 | 4 | 2 | 0 | 0 | 0 | 6.9 | 3.6 | 11.1 | 11.9 | 0.4 | 3.3 | 1.16 |
| Bennett Sousa* | | mr | 30 | 2 | 0 | 0 | 3 | 2 | 0 | 0 | 2 | 8.0 | 3.6 | 12.3 | 10.1 | 2.2 | 2.8 | 1.29 |
| Gabe Speier* | Was | mr | 30 | 19 | 5 | 0 | 2 | 6 | 1 | 0 | 3 | 8.8 | 2.4 | 11.4 | 9.4 | 1.6 | 3.8 | 1.25 |
| Mitch Spence | SF | sp | 27 | 18 | 4 | 0 | 5 | 3 | 1 | 0 | 4 | 10.9 | 2.7 | 14.1 | 6.5 | 0.8 | 2.4 | 1.51 |
| Jeffrey Springs* | Bos | sp | 32 | 18 | 10 | 0 | 6 | 2 | 3 | 0 | 1 | 7.3 | 2.4 | 10.0 | 8.5 | 1.0 | 3.5 | 1.08 |
| Brandon Sproat | NYN | sp | 24 | 33 | 13 | 1 | 9 | 7 | 2 | 2 | 2 | 7.5 | 3.6 | 11.7 | 8.4 | 0.7 | 2.3 | 1.24 |
| Ryne Stanek | | mr | 33 | 6 | 1 | 0 | 0 | 1 | 0 | 0 | 3 | 10.6 | 4.0 | 14.6 | 9.3 | 1.6 | 2.3 | 1.62 |
| Justin Steele* | Tex | sp | 29 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.4 | 4.6 | 10.8 | 11.6 | 1.5 | 2.5 | 1.11 |
| Trevor Stephan | Pit | mr | 29 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.4 | 4.7 | 15.3 | 16.4 | 0.0 | 3.5 | 1.57 |
| Robert Stephenson | | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 3.4 | 10.1 | 16.9 | 1.1 | 5.0 | 1.13 |
| Brock Stewart | Tex | mr | 33 | 4 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 4.4 | 2.8 | 7.4 | 12.5 | 0.3 | 4.5 | 0.80 |
| Matt Strahm* | | mr | 33 | 10 | 2 | 0 | 6 | 0 | 3 | 0 | 0 | 6.8 | 1.7 | 8.9 | 12.3 | 1.0 | 7.3 | 0.94 |
| Hunter Stratton | Mia | mr | 28 | 1 | 2 | 1 | 0 | 3 | 0 | 0 | 0 | 8.7 | 5.4 | 14.1 | 9.9 | 1.2 | 1.8 | 1.57 |
| Spencer Strider | Sea | sp | 26 | 30 | 13 | 0 | 7 | 6 | 0 | 0 | 3 | 6.9 | 2.2 | 9.5 | 12.0 | 0.7 | 5.4 | 1.01 |
| Marcus Stroman | Pit | sp | 34 | 12 | 1 | 0 | 0 | 0 | 0 | 1 | 2 | 9.8 | 3.3 | 13.1 | 7.9 | 1.0 | 2.4 | 1.46 |
| Tyler Stuart | SD | sp | 25 | 3 | 2 | 0 | 1 | 1 | 0 | 0 | 1 | 9.2 | 3.1 | 12.7 | 4.6 | 1.0 | 1.5 | 1.36 |
| Jose Suarez* | LAA | sp | 27 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 10.2 | 4.8 | 15.6 | 10.2 | 1.2 | 2.1 | 1.67 |
| Ranger Suarez* | ChN | sp | 29 | 23 | 13 | 3 | 3 | 6 | 0 | 0 | 2 | 7.3 | 2.7 | 10.1 | 7.8 | 0.8 | 2.9 | 1.11 |
| Robert Suarez | Tam | cl | 34 | 7 | 1 | 1 | 5 | 1 | 0 | 0 | 1 | 8.6 | 3.0 | 12.1 | 10.2 | 1.0 | 3.4 | 1.28 |
| Tomoyuki Sugano | ChN | sp | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.5 | 1.1 | 5.6 | 3.4 | 0.0 | 3.0 | 0.63 |
| Brent Suter* | LAN | mr | 35 | 16 | 0 | 1 | 7 | 2 | 0 | 0 | 5 | 8.3 | 2.5 | 11.5 | 6.8 | 0.8 | 2.7 | 1.20 |
| Erik Swanson | Tor | mr | 31 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 1.0 | 10.0 | 13.0 | 1.0 | 13.0 | 1.11 |
| Jameson Taillon | Tam | sp | 33 | 23 | 5 | 0 | 0 | 0 | 0 | 0 | 3 | 8.4 | 2.5 | 10.9 | 7.5 | 1.1 | 3.0 | 1.21 |
| Dillon Tate | Tex | mr | 31 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 9.3 | 3.4 | 12.7 | 10.1 | 0.0 | 3.0 | 1.41 |
| Troy Taylor | SF | mr | 23 | 8 | 2 | 0 | 4 | 13 | 0 | 0 | 3 | 11.1 | 6.0 | 17.8 | 9.9 | 1.4 | 1.7 | 1.90 |
| Kai-Wei Teng | Hou | sp | 26 | 9 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 13.5 | 4.7 | 18.6 | 4.7 | 1.9 | 1.0 | 2.02 |
| Emiliano Teodo | Tex | sp | 24 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.9 | 0.0 | 7.7 | 3.9 | 0.0 | 99.0 | 0.43 |
| Caleb Thielbar* | | mr | 38 | 5 | 1 | 2 | 1 | 2 | 1 | 0 | 0 | 10.2 | 4.2 | 14.5 | 11.2 | 1.3 | 2.7 | 1.60 |
| Keegan Thompson | Det | mr | 30 | 11 | 7 | 0 | 4 | 5 | 0 | 0 | 4 | 5.9 | 4.4 | 10.9 | 10.2 | 0.9 | 2.3 | 1.15 |
| Ryan Thompson | Bos | mr | 33 | 11 | 1 | 1 | 3 | 0 | 2 | 0 | 1 | 7.1 | 2.5 | 9.9 | 7.4 | 1.0 | 3.0 | 1.06 |
| Trent Thornton | Mil | mr | 31 | 7 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 8.5 | 2.2 | 10.9 | 7.3 | 1.0 | 3.3 | 1.19 |
| Blade Tidwell | Mil | sp | 24 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 9.3 | 3.7 | 13.0 | 6.5 | 4.7 | 1.8 | 1.45 |
| Jesus Tinoco | Atl | mr | 30 | 5 | 3 | 0 | 2 | 0 | 0 | 0 | 3 | 5.0 | 5.0 | 10.6 | 8.1 | 1.1 | 1.6 | 1.11 |
| Jonah Tong | Bos | sp | 22 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 4.0 | 13.0 | 12.0 | 2.0 | 3.0 | 1.44 |
| Michael Tonkin | NYA | mr | 35 | 2 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 9.7 | 4.6 | 15.3 | 5.1 | 1.0 | 1.1 | 1.58 |
| Justin Topa | | mr | 34 | 7 | 3 | 0 | 4 | 3 | 0 | 0 | 2 | 7.2 | 3.2 | 11.0 | 8.8 | 0.3 | 2.8 | 1.15 |
| Blake Treinen | | mr | 37 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 12.3 | 3.1 | 15.3 | 9.2 | 0.6 | 3.0 | 1.70 |
| Edwin Uceta | | mr | 27 | 12 | 2 | 2 | 4 | 0 | 1 | 0 | 2 | 5.0 | 3.5 | 8.9 | 10.6 | 0.7 | 3.1 | 0.95 |
| Miguel Ullola | StL | sp | 23 | 28 | 3 | 0 | 5 | 10 | 0 | 0 | 5 | 9.5 | 5.8 | 15.8 | 8.0 | 1.2 | 1.4 | 1.70 |
| Abner Uribe | Sea | mr | 25 | 13 | 4 | 1 | 8 | 5 | 1 | 0 | 0 | 3.9 | 5.2 | 10.2 | 12.1 | 0.4 | 2.3 | 1.01 |
| Jose Urquidy | Cle | sp | 30 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 36.0 | 9.0 | 45.0 | 9.0 | 0.0 | 1.0 | 5.00 |
| Framber Valdez* | LAA | sp | 31 | 29 | 5 | 0 | 5 | 7 | 0 | 0 | 2 | 7.1 | 3.3 | 10.6 | 9.3 | 0.7 | 2.8 | 1.15 |
| CJ Van Eyk | LAN | sp | 26 | 39 | 15 | 0 | 10 | 10 | 0 | 0 | 6 | 11.8 | 3.2 | 15.6 | 6.3 | 1.8 | 2.0 | 1.67 |
| Carlos Vargas | Sea | mr | 25 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 10.1 | 1.7 | 13.5 | 10.1 | 0.0 | 6.0 | 1.31 |
| Louie Varland | Atl | sp | 27 | 6 | 5 | 1 | 6 | 1 | 0 | 0 | 3 | 7.5 | 2.6 | 10.8 | 8.5 | 1.3 | 3.2 | 1.13 |
| Mike Vasil | SD | sp | 25 | 9 | 2 | 1 | 5 | 5 | 0 | 0 | 4 | 6.9 | 2.4 | 10.3 | 8.7 | 0.8 | 3.6 | 1.03 |
| Randy Vasquez | NYA | sp | 26 | 29 | 4 | 0 | 5 | 8 | 1 | 1 | 8 | 8.5 | 4.3 | 13.3 | 7.3 | 0.8 | 1.7 | 1.43 |
| Justin Verlander | | sp | 42 | 22 | 2 | 0 | 5 | 7 | 3 | 1 | 2 | 8.6 | 2.5 | 11.4 | 7.1 | 0.9 | 2.9 | 1.23 |
| Alex Vesia* | Atl | mr | 29 | 9 | 2 | 3 | 2 | 5 | 0 | 0 | 2 | 9.2 | 4.5 | 14.0 | 12.2 | 0.8 | 2.7 | 1.52 |
| Will Vest | Sac | mr | 30 | 3 | 4 | 1 | 2 | 4 | 0 | 0 | 3 | 6.9 | 3.3 | 10.4 | 8.4 | 0.3 | 2.5 | 1.13 |
| Victor Vodnik | LAA | mr | 25 | 1 | 0 | 0 | 2 | 4 | 0 | 0 | 1 | 6.6 | 3.9 | 11.0 | 9.4 | 1.3 | 2.4 | 1.17 |
| Michael Wacha | | sp | 33 | 9 | 6 | 0 | 5 | 3 | 0 | 0 | 5 | 10.5 | 2.9 | 13.8 | 7.8 | 1.1 | 2.7 | 1.50 |
| Hurston Waldrep | Atl | sp | 23 | 27 | 5 | 0 | 7 | 7 | 1 | 0 | 2 | 9.2 | 5.4 | 15.3 | 8.9 | 0.9 | 1.7 | 1.62 |
| Josh Walker* | Cin | mr | 30 | 2 | 2 | 0 | 3 | 1 | 0 | 0 | 4 | 7.9 | 2.6 | 11.1 | 8.6 | 1.1 | 3.3 | 1.17 |
| Ryan Walker | Phi | mr | 29 | 4 | 2 | 1 | 4 | 2 | 0 | 0 | 1 | 6.8 | 2.8 | 10.2 | 11.9 | 0.8 | 4.2 | 1.06 |
| Andrew Walters | Mia | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.5 | 9.8 | 12.3 | 9.8 | 0.0 | 1.0 | 1.36 |
| Will Warren | ChN | sp | 26 | 6 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 4.9 | 4.9 | 10.6 | 12.3 | 0.0 | 2.5 | 1.09 |
| Ryan Weathers* | Col | sp | 25 | 4 | 3 | 0 | 3 | 0 | 0 | 0 | 2 | 7.1 | 1.9 | 9.6 | 9.9 | 1.1 | 5.3 | 1.00 |
| Luke Weaver | Tam | mr | 31 | 8 | 2 | 0 | 3 | 2 | 0 | 0 | 2 | 8.2 | 3.8 | 12.3 | 10.8 | 1.1 | 2.8 | 1.33 |
| Jacob Webb | Mil | mr | 31 | 19 | 8 | 1 | 11 | 8 | 2 | 1 | 4 | 9.7 | 3.8 | 14.7 | 8.9 | 0.9 | 2.3 | 1.51 |
| Logan Webb | Sac | sp | 28 | 39 | 8 | 0 | 6 | 2 | 0 | 1 | 3 | 8.3 | 2.4 | 10.9 | 7.3 | 0.9 | 3.1 | 1.19 |
| Greg Weissert | Mia | mr | 30 | 10 | 0 | 1 | 4 | 3 | 2 | 0 | 3 | 7.9 | 3.3 | 11.7 | 9.4 | 1.3 | 2.8 | 1.24 |
| Tyler Wells | NYA | sp | 30 | 3 | 2 | 0 | 1 | 1 | 0 | 1 | 1 | 9.8 | 1.8 | 11.8 | 5.7 | 1.8 | 3.1 | 1.29 |
| Hayden Wesneski | NYA | mr | 27 | 6 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 5.4 | 3.6 | 9.3 | 8.4 | 0.7 | 2.3 | 1.00 |
| Cameron Weston | Tor | sp | 24 | 9 | 6 | 0 | 5 | 9 | 1 | 0 | 2 | 9.4 | 3.7 | 13.6 | 8.7 | 1.2 | 2.4 | 1.45 |
| Zack Wheeler | Phi | sp | 35 | 24 | 9 | 0 | 5 | 5 | 0 | 1 | 3 | 7.4 | 3.2 | 10.8 | 9.2 | 0.7 | 2.9 | 1.18 |
| Carson Whisenhunt* | KC | sp | 24 | 9 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 8.8 | 3.0 | 11.9 | 8.6 | 1.1 | 2.9 | 1.31 |
| Forrest Whitley | Cin | mr | 27 | 0 | 2 | 1 | 2 | 0 | 0 | 0 | 1 | 4.0 | 5.3 | 10.5 | 9.2 | 0.7 | 1.8 | 1.02 |
| Garrett Whitlock | Sac | mr | 29 | 29 | 14 | 1 | 5 | 4 | 0 | 1 | 5 | 8.1 | 2.1 | 10.4 | 9.2 | 1.0 | 4.5 | 1.13 |
| Jordan Wicks* | | sp | 25 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 13.5 | 10.5 | 24.0 | 9.0 | 3.0 | 0.9 | 2.67 |
| Nathan Wiles | Bal | mr | 26 | 4 | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 11.0 | 1.3 | 12.3 | 4.7 | 2.4 | 3.6 | 1.37 |
| Devin Williams | Min | cl | 30 | 8 | 1 | 1 | 1 | 4 | 0 | 1 | 2 | 5.0 | 3.2 | 8.4 | 12.0 | 0.1 | 3.7 | 0.92 |
| Gavin Williams | Ari | sp | 25 | 24 | 11 | 0 | 5 | 4 | 1 | 1 | 6 | 7.6 | 3.3 | 11.1 | 8.5 | 0.8 | 2.6 | 1.21 |
| Allan Winans | SD | sp | 29 | 18 | 3 | 0 | 5 | 3 | 0 | 1 | 1 | 8.5 | 2.9 | 12.0 | 6.2 | 0.7 | 2.1 | 1.27 |
| Josh Winckowski | KC | mr | 27 | 15 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 7.7 | 1.8 | 9.6 | 7.0 | 0.9 | 3.9 | 1.05 |
| Keaton Winn | SF | sp | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.8 | 1.4 | 4.3 | 12.8 | 0.0 | 9.0 | 0.47 |
| Bryan Woo | Pit | sp | 25 | 26 | 7 | 0 | 7 | 2 | 0 | 1 | 2 | 7.8 | 1.5 | 9.6 | 7.7 | 1.1 | 5.2 | 1.03 |
| Brandon Woodruff | Bos | sp | 32 | 23 | 4 | 0 | 4 | 0 | 1 | 1 | 4 | 7.5 | 3.2 | 11.2 | 9.3 | 0.9 | 2.9 | 1.19 |
| Jaden Woods* | SF | mr | 23 | 10 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 12.1 | 3.3 | 16.0 | 4.7 | 0.6 | 1.4 | 1.71 |
| Simeon Woods Richardso | Pit | sp | 24 | 12 | 1 | 0 | 0 | 2 | 0 | 0 | 1 | 8.9 | 2.8 | 11.7 | 8.4 | 1.1 | 3.0 | 1.30 |
| Kyle Wright | Col | sp | 29 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 1.8 | 11.4 | 8.4 | 2.4 | 4.7 | 1.20 |
| Justin Wrobleski* | Atl | sp | 24 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 8.3 | 4.0 | 12.3 | 9.1 | 1.6 | 2.3 | 1.37 |
| Yoshinobu Yamamoto | Col | sp | 26 | 10 | 6 | 0 | 10 | 10 | 0 | 0 | 3 | 6.4 | 1.9 | 8.7 | 9.8 | 0.8 | 5.2 | 0.92 |
| Ryan Yarbrough* | NYA | mr | 33 | 20 | 1 | 5 | 11 | 1 | 0 | 0 | 4 | 8.1 | 3.7 | 12.6 | 6.6 | 1.8 | 1.8 | 1.31 |
| Kirby Yates | Min | cl | 38 | 13 | 1 | 0 | 6 | 2 | 0 | 0 | 2 | 7.3 | 4.8 | 13.0 | 10.2 | 0.5 | 2.1 | 1.34 |
| Craig Yoho | Bos | mr | 25 | 11 | 5 | 1 | 9 | 8 | 2 | 0 | 2 | 7.8 | 5.0 | 13.8 | 9.9 | 0.8 | 2.0 | 1.42 |
| Brandon Young | Mia | sp | 26 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 10.5 | 2.2 | 12.6 | 4.8 | 0.9 | 2.2 | 1.40 |
| Rob Zastryzny* | | mr | 33 | 6 | 0 | 0 | 2 | 5 | 1 | 1 | 5 | 8.9 | 3.2 | 12.4 | 7.6 | 1.3 | 2.4 | 1.35 |
| Ryan Zeferjahn | | mr | 27 | 5 | 2 | 1 | 8 | 7 | 0 | 1 | 3 | 7.0 | 4.2 | 12.0 | 8.9 | 0.6 | 2.1 | 1.25 |
| Angel Zerpa* | | mr | 25 | 4 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 12.7 | 3.1 | 16.0 | 7.3 | 1.4 | 2.4 | 1.75 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| Andrew Abbott* | Det | sp | 26 | .661 | 402 | .276 | 267 | .418 | 272 | .426 | 64.5 | 3.7 | 3.38 | 3.15 |
| Bryan Abreu | Sea | mr | 28 | .746 | 171 | .374 | 148 | .461 | 150 | .467 | 41.8 | 5.1 | 4.56 | 4.65 |
| Jason Adam | Ari | mr | 33 | .574 | 185 | .292 | 106 | .344 | 109 | .354 | 24.1 | 2.8 | 2.52 | 2.51 |
| Zach Agnos | NYA | mr | 24 | .897 | 232 | .289 | 204 | .575 | 206 | .580 | 61.2 | 6.9 | 6.25 | 5.76 |
| Keegan Akin* | Phi | mr | 30 | .581 | 177 | .226 | 118 | .384 | 119 | .388 | 23.0 | 2.6 | 2.35 | 2.03 |
| Jorge Alcala | | mr | 29 | .675 | 119 | .235 | 94 | .450 | 94 | .450 | 19.8 | 3.4 | 3.06 | 3.20 |
| Sandy Alcantara | Pit | sp | 29 | .633 | 612 | .299 | 340 | .379 | 348 | .388 | 84.0 | 3.4 | 3.13 | 2.94 |
| Sam Aldegheri* | Atl | sp | 23 | .784 | 62 | .355 | 40 | .455 | 42 | .477 | 13.6 | 6.3 | 5.70 | 5.28 |
| Franco Aleman | KC | mr | 25 | .806 | 119 | .286 | 93 | .503 | 96 | .519 | 26.8 | 5.8 | 5.30 | 4.88 |
| Scott Alexander* | NYN | mr | 35 | .614 | 127 | .236 | 66 | .377 | 69 | .394 | 14.6 | 3.0 | 2.67 | 2.37 |
| Tyler Alexander* | ChA | mr | 30 | .769 | 129 | .310 | 81 | .466 | 82 | .471 | 25.8 | 5.8 | 5.32 | 4.67 |
| Logan Allen* | Was | sp | 28 | .752 | 586 | .282 | 382 | .472 | 386 | .477 | 102.4 | 4.8 | 4.39 | 4.29 |
| Elvis Alvarado | Tex | mr | 26 | .595 | 26 | .269 | 16 | .381 | 16 | .381 | 3.6 | 3.1 | 2.83 | 2.42 |
| Jose Alvarado* | Ari | mr | 30 | .731 | 86 | .372 | 67 | .444 | 69 | .457 | 19.1 | 5.2 | 4.63 | 4.41 |
| Kyle Amendt | Atl | mr | 25 | .749 | 97 | .237 | 84 | .500 | 84 | .500 | 21.6 | 5.0 | 4.52 | 4.54 |
| Ian Anderson | NYA | sp | 27 | .823 | 209 | .321 | 156 | .510 | 158 | .516 | 48.6 | 6.7 | 5.97 | 5.74 |
| Tyler Anderson* | Tor | sp | 35 | .628 | 287 | .282 | 150 | .376 | 152 | .381 | 39.6 | 3.7 | 3.38 | 3.01 |
| Shawn Armstrong | Ari | mr | 34 | .676 | 80 | .287 | 52 | .426 | 52 | .426 | 13.5 | 4.3 | 3.81 | 3.14 |
| Spencer Arrighetti | Phi | sp | 25 | .710 | 58 | .293 | 41 | .451 | 41 | .451 | 10.2 | 4.1 | 3.76 | 3.74 |
| Aaron Ashby* | Sea | mr | 27 | .955 | 140 | .400 | 156 | .607 | 157 | .611 | 50.7 | 8.6 | 7.66 | 7.57 |
| Braxton Ashcraft | Atl | sp | 25 | .688 | 436 | .275 | 267 | .431 | 272 | .439 | 68.9 | 4.1 | 3.72 | 3.22 |
| Graham Ashcraft | Was | sp | 27 | .612 | 140 | .257 | 74 | .349 | 82 | .387 | 18.8 | 3.3 | 2.99 | 2.90 |
| Sam Bachman | Tor | sp | 25 | .655 | 124 | .282 | 71 | .386 | 76 | .413 | 17.5 | 3.6 | 3.28 | 3.44 |
| Henry Baez | Tor | sp | 22 | .981 | 187 | .342 | 158 | .622 | 159 | .626 | 54.6 | 9.1 | 8.46 | 7.96 |
| Bryan Baker | Col | mr | 30 | .752 | 118 | .305 | 78 | .464 | 79 | .470 | 21.8 | 5.0 | 4.46 | 3.97 |
| Tanner Banks* | SD | mr | 33 | .643 | 237 | .295 | 143 | .398 | 143 | .398 | 36.3 | 3.8 | 3.46 | 3.12 |
| Scott Barlow | ChN | mr | 32 | .692 | 210 | .238 | 164 | .447 | 169 | .460 | 39.3 | 4.1 | 3.66 | 3.75 |
| Mason Barnett | StL | sp | 24 | .703 | 526 | .287 | 338 | .431 | 348 | .443 | 97.1 | 4.8 | 4.39 | 4.00 |
| Chris Bassitt | Mil | sp | 36 | .773 | 527 | .306 | 371 | .461 | 389 | .483 | 109.1 | 5.5 | 4.98 | 5.29 |
| Brady Basso* | Min | sp | 27 | .696 | 161 | .261 | 99 | .446 | 99 | .446 | 22.8 | 3.7 | 3.43 | 3.23 |
| Felix Bautista | ChN | cl | 30 | .463 | 117 | .205 | 63 | .301 | 64 | .306 | 11.2 | 1.8 | 1.67 | 1.41 |
| Shane Baz | Bal | sp | 26 | .638 | 523 | .302 | 306 | .384 | 311 | .391 | 78.1 | 3.7 | 3.38 | 3.32 |
| Eduard Bazardo | Pit | mr | 29 | .767 | 202 | .347 | 142 | .460 | 147 | .476 | 43.2 | 5.5 | 4.99 | 4.69 |
| Tristan Beck | SF | mr | 29 | .700 | 301 | .282 | 204 | .439 | 208 | .447 | 51.4 | 4.1 | 3.78 | 3.65 |
| Ian Bedell | ChA | sp | 25 | 1.038 | 114 | .368 | 114 | .648 | 116 | .659 | 41.7 | 10.6 | 9.56 | 9.72 |
| David Bednar | LAA | cl | 30 | .570 | 171 | .281 | 97 | .355 | 97 | .355 | 20.4 | 2.6 | 2.41 | 2.16 |
| Jalen Beeks* | LAN | mr | 31 | .798 | 384 | .326 | 272 | .494 | 276 | .501 | 77.5 | 5.6 | 5.10 | 4.83 |
| Clayton Beeter | Col | sp | 26 | .819 | 272 | .342 | 226 | .503 | 231 | .514 | 68.3 | 6.2 | 5.63 | 5.67 |
| Nigel Belgrave | | mr | 23 | .636 | 120 | .192 | 81 | .415 | 84 | .431 | 17.6 | 3.4 | 3.12 | 2.83 |
| Brayan Bello | Mil | sp | 26 | .660 | 463 | .283 | 278 | .404 | 284 | .413 | 65.7 | 3.5 | 3.17 | 3.29 |
| Valente Bellozo | Tor | sp | 25 | .753 | 198 | .303 | 127 | .465 | 128 | .469 | 35.5 | 5.1 | 4.52 | 4.24 |
| Anthony Bender | Mil | mr | 30 | .695 | 104 | .327 | 70 | .409 | 74 | .433 | 17.1 | 3.8 | 3.37 | 4.02 |
| Ryan Bergert | Hou | sp | 25 | .928 | 97 | .340 | 85 | .574 | 87 | .588 | 29.1 | 8.2 | 7.53 | 7.39 |
| Brennan Bernardino* | | mr | 33 | .689 | 155 | .310 | 94 | .390 | 103 | .427 | 25.4 | 4.0 | 3.61 | 3.89 |
| Jose Berrios | | sp | 31 | .722 | 484 | .295 | 311 | .435 | 325 | .455 | 86.0 | 4.5 | 4.11 | 3.83 |
| Prelander Berroa | SF | mr | 25 | .888 | 147 | .340 | 152 | .571 | 154 | .579 | 46.4 | 7.3 | 6.60 | 6.27 |
| Tanner Bibee | Was | sp | 26 | .662 | 513 | .265 | 340 | .422 | 344 | .427 | 81.6 | 3.7 | 3.35 | 3.06 |
| Phil Bickford | ChN | mr | 29 | .599 | 367 | .202 | 227 | .394 | 232 | .403 | 47.0 | 2.8 | 2.55 | 2.15 |
| Osvaldo Bido | | sp | 29 | .722 | 385 | .296 | 270 | .436 | 283 | .457 | 77.6 | 5.0 | 4.54 | 4.51 |
| Shane Bieber | Hou | sp | 30 | .700 | 97 | .320 | 66 | .437 | 66 | .437 | 18.9 | 4.9 | 4.45 | 4.01 |
| Hayden Birdsong | Bos | sp | 23 | .672 | 27 | .296 | 15 | .405 | 15 | .405 | 3.7 | 4.4 | 3.93 | 5.56 |
| Ronel Blanco | Col | sp | 31 | .628 | 113 | .265 | 68 | .386 | 70 | .398 | 15.2 | 3.1 | 2.88 | 3.15 |
| A.J. Blubaugh | | sp | 24 | .641 | 372 | .261 | 218 | .390 | 226 | .404 | 52.6 | 3.4 | 3.10 | 3.01 |
| Ryan Borucki* | LAN | mr | 31 | .707 | 157 | .280 | 125 | .439 | 131 | .460 | 34.2 | 4.9 | 4.31 | 4.70 |
| Matt Boyd* | Tex | sp | 34 | .590 | 369 | .214 | 224 | .386 | 227 | .391 | 44.2 | 2.6 | 2.41 | 2.23 |
| Joe Boyle | NYA | sp | 25 | .882 | 382 | .325 | 402 | .557 | 411 | .569 | 136.3 | 8.8 | 8.06 | 8.15 |
| Kyle Bradish | Bal | sp | 28 | .434 | 121 | .248 | 48 | .246 | 51 | .262 | 8.8 | 1.5 | 1.41 | 1.29 |
| Taj Bradley | | sp | 24 | .696 | 437 | .288 | 305 | .429 | 314 | .442 | 79.5 | 4.2 | 3.80 | 3.86 |
| Matt Brash | Col | mr | 27 | .687 | 221 | .344 | 179 | .432 | 182 | .440 | 46.4 | 4.3 | 3.95 | 3.76 |
| Ryan Brasier | Pit | mr | 37 | .693 | 120 | .283 | 70 | .422 | 73 | .440 | 18.6 | 4.1 | 3.71 | 2.99 |
| Mitch Bratt* | StL | sp | 21 | .627 | 307 | .238 | 171 | .394 | 173 | .399 | 41.3 | 3.5 | 3.15 | 2.87 |
| Lucas Braun | | sp | 23 | .859 | 131 | .389 | 102 | .515 | 105 | .530 | 33.7 | 7.0 | 6.39 | 5.93 |
| Huascar Brazoban | NYN | mr | 35 | .643 | 263 | .285 | 168 | .401 | 170 | .406 | 41.6 | 3.8 | 3.47 | 3.49 |
| John Brebbia | ChA | mr | 35 | .722 | 141 | .333 | 106 | .447 | 108 | .456 | 28.5 | 4.7 | 4.24 | 4.11 |
| Jhony Brito | ChA | mr | 27 | .618 | 419 | .232 | 225 | .391 | 228 | .396 | 51.2 | 3.1 | 2.87 | 2.52 |
| Ben Brown | Sea | sp | 25 | .655 | 406 | .273 | 284 | .413 | 290 | .422 | 69.5 | 3.8 | 3.47 | 3.42 |
| Hunter Brown | Mia | sp | 26 | .661 | 513 | .298 | 339 | .409 | 347 | .419 | 86.8 | 3.9 | 3.50 | 3.18 |
| Kris Bubic* | Tex | mr | 27 | .581 | 213 | .254 | 118 | .361 | 120 | .367 | 25.6 | 2.8 | 2.56 | 2.31 |
| Walker Buehler | Phi | sp | 30 | .605 | 437 | .249 | 240 | .374 | 248 | .386 | 56.8 | 3.1 | 2.84 | 2.29 |
| J.B. Bukauskas | LAN | mr | 28 | .636 | 8 | .375 | 4 | .364 | 4 | .364 | 1.2 | 4.2 | 3.74 | 2.52 |
| Aaron Bummer* | | mr | 31 | .565 | 179 | .302 | 99 | .331 | 103 | .344 | 23.3 | 2.8 | 2.51 | 2.28 |
| Brock Burke* | | mr | 28 | .641 | 248 | .302 | 152 | .391 | 154 | .396 | 35.4 | 3.4 | 3.07 | 3.18 |
| Sean Burke | LAA | sp | 25 | .836 | 89 | .337 | 77 | .535 | 77 | .535 | 23.0 | 6.3 | 5.76 | 5.33 |
| Corbin Burnes | Ari | sp | 30 | .556 | 253 | .265 | 126 | .332 | 130 | .343 | 28.9 | 2.7 | 2.51 | 2.20 |
| Tanner Burns | ChA | mr | 26 | .773 | 450 | .291 | 333 | .478 | 345 | .495 | 100.2 | 5.9 | 5.36 | 5.41 |
| Ryan Burr | KC | mr | 31 | .345 | 13 | .154 | 8 | .242 | 8 | .242 | 1.1 | 1.1 | 0.99 | 0.76 |
| Mike Burrows | Sea | sp | 25 | .892 | 21 | .381 | 17 | .531 | 18 | .563 | 6.1 | 8.3 | 7.07 | 6.27 |
| Jose Butto | | mr | 27 | .802 | 181 | .287 | 149 | .498 | 155 | .518 | 43.7 | 6.0 | 5.34 | 5.78 |
| Edward Cabrera | Atl | sp | 27 | .696 | 279 | .276 | 210 | .448 | 212 | .452 | 52.3 | 4.2 | 3.81 | 3.86 |
| Jean Cabrera | Tor | sp | 23 | .894 | 147 | .327 | 122 | .542 | 128 | .569 | 39.2 | 7.4 | 6.65 | 6.83 |
| Noah Cameron* | Cin | sp | 25 | .646 | 378 | .262 | 223 | .401 | 227 | .408 | 52.7 | 3.5 | 3.15 | 3.05 |
| Griffin Canning | StL | sp | 29 | .868 | 217 | .290 | 167 | .549 | 169 | .556 | 52.9 | 7.2 | 6.52 | 5.99 |
| Jonathan Cannon | SD | sp | 24 | .753 | 68 | .353 | 45 | .446 | 46 | .455 | 13.6 | 5.6 | 5.00 | 5.00 |
| Yennier Cano | ChN | mr | 31 | .512 | 242 | .219 | 119 | .318 | 122 | .326 | 23.8 | 2.3 | 2.05 | 1.81 |
| Joey Cantillo* | SF | sp | 25 | .806 | 292 | .370 | 247 | .500 | 248 | .502 | 74.3 | 6.4 | 5.75 | 6.15 |
| Ben Casparius | ChA | sp | 26 | .829 | 205 | .317 | 172 | .517 | 175 | .526 | 54.7 | 6.9 | 6.27 | 6.37 |
| Jose Castillo* | ChN | mr | 29 | .733 | 49 | .245 | 36 | .474 | 37 | .487 | 8.7 | 4.4 | 3.90 | 4.10 |
| Luis Castillo | Bos | sp | 32 | .597 | 515 | .289 | 301 | .366 | 307 | .373 | 66.0 | 2.9 | 2.59 | 2.51 |
| Miguel Castro | Min | mr | 30 | .793 | 87 | .299 | 71 | .500 | 73 | .514 | 20.0 | 5.6 | 5.06 | 5.20 |
| Cade Cavalli | Sac | sp | 26 | .684 | 325 | .283 | 225 | .418 | 238 | .442 | 56.3 | 3.9 | 3.53 | 3.50 |
| Dylan Cease | Mil | sp | 29 | .643 | 443 | .273 | 305 | .405 | 314 | .417 | 71.6 | 3.5 | 3.20 | 3.11 |
| Slade Cecconi | SD | sp | 26 | .687 | 423 | .262 | 248 | .421 | 255 | .433 | 65.5 | 4.1 | 3.74 | 3.48 |
| Andrew Chafin* | Sac | mr | 35 | .833 | 70 | .414 | 60 | .508 | 60 | .508 | 17.7 | 6.4 | 5.72 | 6.62 |
| Bubba Chandler | SF | sp | 22 | .736 | 214 | .294 | 153 | .464 | 155 | .470 | 40.6 | 4.8 | 4.47 | 4.37 |
| Aroldis Chapman* | LAA | mr | 37 | .789 | 137 | .314 | 151 | .512 | 154 | .522 | 43.6 | 6.1 | 5.43 | 5.56 |
| Jesse Chavez | ChA | mr | 41 | .715 | 59 | .288 | 40 | .460 | 40 | .460 | 10.2 | 4.5 | 4.08 | 3.64 |
| Po-Yu Chen | StL | sp | 23 | .749 | 87 | .333 | 48 | .429 | 50 | .446 | 14.7 | 5.1 | 4.63 | 4.61 |
| Jack Choate* | ChN | sp | 24 | .250 | 1 | .000 | 1 | .250 | 1 | .250 | 0.0 | 0.0 | 0.00 | 0.71 |
| Marc Church | Mil | mr | 24 | .771 | 100 | .270 | 81 | .509 | 81 | .509 | 21.7 | 5.2 | 4.74 | 3.97 |
| Aaron Civale | Min | sp | 30 | .867 | 66 | .273 | 65 | .565 | 67 | .583 | 18.5 | 6.5 | 5.76 | 5.73 |
| Emmanuel Clase | Sea | cl | 27 | .583 | 135 | .289 | 69 | .340 | 72 | .355 | 17.3 | 3.1 | 2.85 | 2.47 |
| Garrett Cleavinger* | Ari | mr | 31 | .678 | 203 | .276 | 144 | .420 | 151 | .440 | 34.7 | 3.8 | 3.47 | 3.70 |
| Adisyn Coffey | Hou | mr | 26 | .937 | 79 | .304 | 66 | .606 | 66 | .606 | 20.9 | 8.2 | 7.70 | 7.42 |
| Roansy Contreras | Det | mr | 25 | .663 | 480 | .262 | 306 | .423 | 307 | .424 | 76.5 | 3.9 | 3.55 | 3.15 |
| Nestor Cortes* | | sp | 30 | .648 | 169 | .278 | 99 | .399 | 100 | .403 | 25.0 | 3.7 | 3.32 | 3.13 |
| Danny Coulombe* | Det | mr | 35 | .652 | 186 | .253 | 125 | .421 | 126 | .424 | 29.5 | 3.6 | 3.33 | 2.94 |
| Austin Cox* | ChA | mr | 28 | .710 | 137 | .314 | 84 | .418 | 87 | .433 | 21.4 | 4.2 | 3.80 | 4.91 |
| Cooper Criswell | Mil | sp | 28 | .864 | 106 | .321 | 76 | .503 | 81 | .536 | 23.5 | 6.2 | 5.66 | 6.04 |
| Garrett Crochet* | Cle | sp | 26 | .581 | 378 | .317 | 237 | .355 | 241 | .361 | 52.5 | 2.8 | 2.56 | 2.36 |
| Declan Cronin | Tam | mr | 27 | .688 | 102 | .304 | 61 | .418 | 62 | .425 | 14.3 | 3.5 | 3.19 | 3.46 |
| Fernando Cruz | Hou | mr | 35 | .633 | 268 | .280 | 216 | .412 | 221 | .422 | 49.6 | 3.5 | 3.21 | 2.95 |
| Yoniel Curet | Sac | sp | 22 | .840 | 52 | .327 | 53 | .546 | 53 | .546 | 15.5 | 6.5 | 5.98 | 6.06 |
| Xzavion Curry | SF | sp | 26 | .819 | 208 | .298 | 156 | .515 | 158 | .521 | 44.3 | 5.7 | 5.23 | 5.55 |
| Caden Dana | NYA | sp | 21 | .783 | 67 | .313 | 44 | .473 | 46 | .495 | 14.1 | 5.8 | 5.27 | 4.22 |
| Davis Daniel | Phi | sp | 28 | .721 | 330 | .276 | 203 | .448 | 206 | .455 | 57.7 | 4.9 | 4.40 | 3.92 |
| Hagen Danner | Cin | mr | 26 | .824 | 90 | .356 | 75 | .510 | 77 | .524 | 22.4 | 6.1 | 5.43 | 5.14 |
| Yu Darvish | | sp | 38 | .634 | 170 | .247 | 103 | .396 | 107 | .412 | 25.2 | 3.5 | 3.22 | 2.87 |
| Duncan Davitt | StL | sp | 25 | .785 | 276 | .301 | 189 | .478 | 195 | .494 | 55.9 | 5.6 | 5.07 | 4.80 |
| Enyel de los Santos | Mil | mr | 29 | .726 | 98 | .276 | 72 | .453 | 74 | .465 | 19.5 | 4.9 | 4.46 | 4.91 |
| Yerry de los Santos | NYA | mr | 27 | .698 | 125 | .264 | 75 | .431 | 77 | .443 | 20.1 | 4.3 | 3.91 | 3.79 |
| Jacob deGrom | | sp | 37 | .633 | 391 | .307 | 270 | .399 | 273 | .404 | 67.8 | 3.7 | 3.31 | 2.74 |
| Reid Detmers* | | sp | 25 | .778 | 88 | .352 | 65 | .471 | 66 | .478 | 17.7 | 5.1 | 4.57 | 5.26 |
| Alexis Diaz | Det | cl | 28 | .612 | 223 | .265 | 137 | .382 | 142 | .396 | 31.3 | 3.3 | 2.99 | 3.06 |
| Edwin Diaz | LAA | cl | 31 | .690 | 145 | .352 | 129 | .437 | 131 | .444 | 33.3 | 4.3 | 3.91 | 3.77 |
| Miguel Diaz | | mr | 30 | .648 | 207 | .295 | 118 | .387 | 122 | .400 | 29.5 | 3.6 | 3.19 | 3.08 |
| Yilber Diaz | Hou | sp | 24 | .696 | 393 | .254 | 257 | .437 | 264 | .449 | 66.6 | 4.3 | 3.93 | 3.70 |
| Hunter Dobbins | Sea | sp | 25 | .642 | 44 | .295 | 25 | .368 | 27 | .397 | 6.2 | 3.4 | 3.14 | 3.27 |
| Dylan Dodd* | Sac | sp | 27 | .988 | 25 | .360 | 25 | .641 | 25 | .641 | 8.1 | 8.4 | 7.58 | 6.47 |
| Chase Dollander | Ari | sp | 23 | .715 | 178 | .309 | 114 | .421 | 122 | .450 | 34.8 | 5.3 | 4.83 | 4.46 |
| Seranthony Dominguez | Was | mr | 30 | .688 | 194 | .247 | 147 | .438 | 153 | .455 | 37.5 | 4.2 | 3.79 | 3.62 |
| Camilo Doval | Cle | cl | 27 | .640 | 129 | .302 | 94 | .402 | 97 | .415 | 21.3 | 3.3 | 3.00 | 2.67 |
| Jack Dreyer* | KC | mr | 26 | .637 | 300 | .300 | 198 | .399 | 199 | .401 | 47.8 | 3.6 | 3.24 | 3.00 |
| Jhoan Duran | Sea | cl | 27 | .536 | 203 | .251 | 119 | .333 | 124 | .347 | 25.0 | 2.5 | 2.23 | 1.89 |
| Zach Eflin | | sp | 31 | .760 | 355 | .335 | 226 | .457 | 230 | .466 | 66.5 | 5.3 | 4.71 | 4.47 |
| Brandon Eisert* | Det | mr | 27 | .823 | 153 | .379 | 113 | .496 | 113 | .496 | 34.1 | 6.0 | 5.46 | 5.53 |
| Bryce Elder | NYN | sp | 26 | .670 | 599 | .249 | 363 | .421 | 370 | .429 | 87.1 | 3.7 | 3.37 | 3.37 |
| Magnus Ellerts | Atl | mr | 24 | .863 | 189 | .381 | 171 | .533 | 174 | .542 | 52.0 | 6.7 | 5.96 | 6.31 |
| Mason Englert | Atl | mr | 25 | 1.000 | 6 | .500 | 3 | .500 | 3 | .500 | 1.5 | 13.5 | 12.15 | 14.52 |
| Nic Enright | Cin | mr | 28 | .763 | 247 | .348 | 169 | .459 | 173 | .470 | 47.3 | 5.0 | 4.46 | 4.48 |
| Nathan Eovaldi | Sac | sp | 35 | .550 | 209 | .273 | 97 | .319 | 101 | .332 | 19.9 | 2.3 | 2.04 | 2.00 |
| Lucas Erceg | LAN | mr | 30 | .665 | 197 | .269 | 133 | .414 | 139 | .433 | 30.4 | 3.4 | 3.16 | 3.07 |
| Carlos Estevez | | cl | 32 | .680 | 205 | .263 | 147 | .438 | 149 | .443 | 36.6 | 4.0 | 3.66 | 3.36 |
| Jeremiah Estrada | Sea | mr | 26 | .699 | 183 | .328 | 148 | .433 | 153 | .447 | 39.8 | 4.6 | 4.05 | 3.90 |
| Logan Evans | Tor | sp | 24 | .727 | 138 | .290 | 89 | .438 | 93 | .458 | 23.1 | 4.5 | 4.10 | 4.41 |
| Pete Fairbanks | ChN | cl | 31 | .642 | 175 | .257 | 116 | .410 | 118 | .417 | 27.4 | 3.6 | 3.28 | 3.23 |
| Bailey Falter* | KC | sp | 28 | .762 | 303 | .323 | 194 | .465 | 196 | .470 | 54.7 | 5.0 | 4.49 | 4.27 |
| Calvin Faucher | | mr | 29 | .771 | 203 | .350 | 141 | .449 | 148 | .471 | 43.9 | 5.8 | 5.21 | 5.16 |
| Erick Fedde | Tam | sp | 32 | .819 | 190 | .358 | 157 | .515 | 158 | .518 | 47.8 | 6.5 | 5.81 | 5.53 |
| Ryan Feltner | Mil | sp | 28 | .707 | 119 | .244 | 81 | .466 | 81 | .466 | 19.9 | 4.2 | 3.71 | 3.11 |
| Caleb Ferguson* | LAA | mr | 28 | .701 | 170 | .306 | 104 | .414 | 108 | .430 | 28.5 | 4.4 | 3.98 | 4.30 |
| Ryan Fernandez | | mr | 27 | .811 | 136 | .301 | 114 | .518 | 115 | .523 | 34.9 | 6.3 | 5.77 | 5.23 |
| Jose A. Ferrer* | Hou | mr | 25 | .604 | 247 | .287 | 129 | .358 | 132 | .367 | 30.3 | 3.0 | 2.79 | 2.73 |
| David Festa | Hou | sp | 25 | .831 | 210 | .357 | 173 | .518 | 176 | .527 | 55.1 | 6.8 | 6.17 | 5.53 |
| Kyle Finnegan | NYN | cl | 33 | .721 | 146 | .267 | 109 | .445 | 115 | .469 | 30.2 | 4.7 | 4.20 | 4.18 |
| Braydon Fisher | LAN | mr | 24 | .810 | 276 | .312 | 219 | .506 | 222 | .513 | 64.8 | 6.1 | 5.43 | 5.24 |
| Jack Flaherty | | sp | 29 | .645 | 379 | .282 | 255 | .396 | 264 | .410 | 61.4 | 3.5 | 3.17 | 3.21 |
| Jose Fleury | StL | sp | 23 | .785 | 407 | .290 | 305 | .497 | 308 | .502 | 88.7 | 5.7 | 5.26 | 5.03 |
| Dylan Floro | Was | mr | 34 | .550 | 212 | .278 | 93 | .314 | 96 | .324 | 22.2 | 2.7 | 2.53 | 2.36 |
| Mason Fluharty* | | mr | 23 | .711 | 266 | .274 | 185 | .449 | 188 | .456 | 47.8 | 4.4 | 3.93 | 3.63 |
| Jason Foley | Sac | cl | 29 | .619 | 19 | .368 | 13 | .371 | 13 | .371 | 3.2 | 3.7 | 3.52 | 3.44 |
| J.P. France | KC | sp | 30 | .759 | 109 | .275 | 79 | .482 | 80 | .488 | 19.6 | 4.5 | 3.98 | 4.38 |
| Bowden Francis | Tex | sp | 29 | .583 | 213 | .221 | 111 | .362 | 116 | .378 | 24.1 | 2.7 | 2.48 | 1.93 |
| Max Fried* | Ari | sp | 31 | .670 | 635 | .302 | 371 | .403 | 379 | .412 | 96.1 | 3.9 | 3.54 | 3.36 |
| Kody Funderburk* | | mr | 28 | .805 | 116 | .328 | 82 | .469 | 88 | .503 | 26.8 | 6.4 | 5.82 | 5.62 |
| Hunter Gaddis | Bos | mr | 27 | .695 | 400 | .268 | 267 | .435 | 277 | .451 | 68.6 | 4.2 | 3.79 | 3.35 |
| Matt Gage* | NYA | mr | 32 | .926 | 25 | .440 | 20 | .541 | 20 | .541 | 6.3 | 7.4 | 6.94 | 8.26 |
| Zac Gallen | Mia | sp | 29 | .668 | 598 | .276 | 380 | .411 | 394 | .426 | 94.5 | 3.8 | 3.42 | 3.26 |
| Brandyn Garcia* | Bal | sp | 25 | 1.167 | 2 | .500 | 2 | .667 | 2 | .667 | 1.2 | 32.0 | 28.84 | 29.63 |
| Luis A. Garcia | | mr | 38 | .779 | 220 | .382 | 141 | .452 | 142 | .455 | 44.4 | 5.8 | 5.18 | 4.86 |
| Robert Garcia* | Was | mr | 29 | .563 | 178 | .275 | 109 | .359 | 110 | .362 | 21.7 | 2.5 | 2.34 | 2.05 |
| Yimi Garcia | Hou | mr | 34 | .777 | 61 | .230 | 50 | .515 | 50 | .515 | 11.8 | 4.4 | 4.00 | 3.61 |
| Reed Garrett | NYN | mr | 32 | .626 | 188 | .319 | 136 | .394 | 138 | .400 | 31.0 | 3.4 | 3.03 | 2.98 |
| Robert Gasser* | Cin | sp | 26 | .655 | 76 | .289 | 45 | .375 | 49 | .408 | 12.9 | 4.2 | 3.69 | 3.27 |
| Kevin Gausman | Min | sp | 34 | .700 | 555 | .277 | 360 | .442 | 365 | .448 | 93.8 | 4.3 | 3.92 | 3.47 |
| Paul Gervase | | mr | 25 | .704 | 227 | .286 | 174 | .452 | 176 | .457 | 46.0 | 4.8 | 4.32 | 4.16 |
| Kyle Gibson | Bos | sp | 37 | .737 | 110 | .255 | 78 | .476 | 79 | .482 | 20.3 | 4.8 | 4.28 | 4.24 |
| Luis Gil | SD | sp | 27 | .698 | 91 | .253 | 76 | .461 | 77 | .467 | 17.8 | 3.9 | 3.64 | 3.36 |
| Logan Gilbert | Ari | sp | 28 | .677 | 398 | .334 | 246 | .403 | 250 | .410 | 66.6 | 4.1 | 3.78 | 3.53 |
| Kevin Ginkel | | mr | 31 | .564 | 122 | .279 | 65 | .344 | 66 | .349 | 14.6 | 2.9 | 2.54 | 2.28 |
| J.T. Ginn | | sp | 26 | .767 | 187 | .326 | 124 | .458 | 128 | .472 | 35.9 | 5.2 | 4.74 | 4.89 |
| Lucas Giolito | Mia | sp | 30 | .794 | 53 | .321 | 41 | .500 | 41 | .500 | 12.4 | 6.0 | 5.50 | 4.38 |
| Sawyer Gipson-Long | Mia | sp | 27 | .895 | 75 | .347 | 71 | .573 | 72 | .581 | 22.5 | 7.2 | 6.51 | 6.08 |
| Tyler Glasnow | Sea | sp | 31 | .691 | 295 | .312 | 213 | .434 | 215 | .438 | 56.1 | 4.3 | 3.85 | 3.57 |
| Yoendrys Gomez | SD | sp | 25 | .550 | 29 | .207 | 19 | .373 | 19 | .373 | 4.0 | 2.9 | 2.71 | 2.69 |
| Tony Gonsolin | Tex | sp | 31 | .625 | 106 | .245 | 60 | .392 | 61 | .399 | 13.3 | 3.1 | 2.77 | 2.68 |
| Colton Gordon* | | sp | 26 | .670 | 331 | .266 | 211 | .419 | 214 | .425 | 58.1 | 4.3 | 3.93 | 3.32 |
| MacKenzie Gore* | | sp | 26 | .700 | 380 | .284 | 267 | .445 | 269 | .448 | 67.8 | 4.2 | 3.88 | 3.65 |
| Gordon Graceffo | Min | sp | 25 | .832 | 103 | .350 | 80 | .510 | 80 | .510 | 23.0 | 5.9 | 5.26 | 5.51 |
| Andre Granillo | NYA | mr | 25 | .984 | 189 | .323 | 201 | .638 | 201 | .638 | 68.6 | 9.6 | 8.63 | 7.99 |
| Kendall Graveman | NYN | mr | 34 | .701 | 53 | .189 | 44 | .468 | 45 | .479 | 10.4 | 4.1 | 3.73 | 3.95 |
| Jon Gray | Sac | sp | 33 | .494 | 82 | .232 | 38 | .292 | 41 | .315 | 7.6 | 2.0 | 1.81 | 1.54 |
| Sonny Gray | Phi | sp | 35 | .578 | 493 | .225 | 299 | .367 | 309 | .380 | 61.0 | 2.6 | 2.37 | 2.32 |
| Chad Green | ChN | mr | 34 | .842 | 161 | .323 | 130 | .537 | 131 | .541 | 33.9 | 5.2 | 4.63 | 4.70 |
| Hunter Greene | Col | sp | 25 | .650 | 162 | .272 | 108 | .403 | 112 | .418 | 26.2 | 3.7 | 3.35 | 3.34 |
| Sean Guenther* | Bal | mr | 29 | 1.214 | 7 | .429 | 6 | .750 | 6 | .750 | 2.6 | 17.8 | 15.98 | 12.64 |
| Luis Guerrero | | mr | 24 | .671 | 135 | .244 | 104 | .426 | 109 | .447 | 25.3 | 4.0 | 3.69 | 4.08 |
| Ryan Gusto | | sp | 26 | .881 | 82 | .341 | 64 | .533 | 66 | .550 | 21.0 | 7.5 | 6.80 | 7.28 |
| Josh Hader* | | cl | 31 | .792 | 82 | .329 | 92 | .520 | 93 | .525 | 24.5 | 5.5 | 4.89 | 4.63 |
| Skylar Hales | Atl | mr | 23 | .805 | 128 | .336 | 107 | .512 | 108 | .517 | 29.3 | 5.4 | 4.94 | 4.99 |
| DL Hall* | Bal | sp | 26 | .611 | 75 | .333 | 51 | .372 | 52 | .380 | 10.8 | 2.9 | 2.65 | 3.21 |
| Seth Halvorsen | Hou | mr | 25 | .620 | 150 | .240 | 93 | .389 | 96 | .402 | 21.4 | 3.3 | 3.02 | 3.15 |
| Ian Hamilton | Tex | mr | 30 | .695 | 298 | .326 | 215 | .432 | 219 | .440 | 51.0 | 3.8 | 3.45 | 3.53 |
| Emerson Hancock | Sea | sp | 26 | .687 | 71 | .310 | 41 | .414 | 41 | .414 | 10.3 | 4.0 | 3.69 | 4.33 |
| Brenan Hanifee | Det | mr | 27 | .669 | 623 | .263 | 370 | .416 | 377 | .424 | 91.6 | 3.8 | 3.45 | 3.27 |
| Landon Harper | Cin | mr | 24 | .539 | 46 | .261 | 16 | .302 | 16 | .302 | 3.0 | 1.9 | 1.64 | 1.58 |
| Thomas Harrington | Sea | sp | 23 | .697 | 377 | .257 | 243 | .435 | 249 | .446 | 64.7 | 4.4 | 4.03 | 4.01 |
| Hayden Harris* | Cle | mr | 26 | 2.175 | 5 | 1.000 | 13 | 1.300 | 13 | 1.300 | 9.2 | 124.4 | 111.97 | 110.30 |
| Kyle Harrison* | | sp | 23 | .702 | 419 | .289 | 277 | .436 | 284 | .447 | 71.4 | 4.2 | 3.80 | 3.59 |
| Kyle Hart* | Mil | sp | 32 | .680 | 500 | .294 | 301 | .411 | 310 | .423 | 76.5 | 3.9 | 3.51 | 3.45 |
| Grant Hartwig | NYN | mr | 27 | .759 | 24 | .333 | 23 | .460 | 25 | .500 | 6.8 | 5.8 | 5.18 | 5.74 |
| Hunter Harvey | Hou | mr | 30 | .555 | 63 | .254 | 31 | .341 | 31 | .341 | 6.8 | 2.7 | 2.55 | 2.21 |
| Brent Headrick* | NYA | sp | 27 | .827 | 105 | .333 | 85 | .515 | 87 | .527 | 25.1 | 5.9 | 5.50 | 5.46 |
| Andrew Heaney* | StL | sp | 34 | .804 | 326 | .294 | 272 | .507 | 280 | .522 | 80.2 | 5.9 | 5.34 | 4.97 |
| Ryan Helsley | Col | cl | 30 | .700 | 153 | .346 | 124 | .440 | 126 | .447 | 31.6 | 4.3 | 3.96 | 3.66 |
| Logan Henderson | SF | sp | 23 | .751 | 411 | .290 | 307 | .468 | 318 | .485 | 88.5 | 5.2 | 4.74 | 4.23 |
| Liam Hendriks | ChN | cl | 36 | .742 | 11 | .455 | 10 | .455 | 10 | .455 | 2.9 | 6.0 | 5.00 | 5.61 |
| Edgardo Henriquez | Atl | mr | 23 | .749 | 84 | .357 | 65 | .458 | 66 | .465 | 19.4 | 6.0 | 5.30 | 5.73 |
| Ronny Henriquez | Tex | mr | 25 | .873 | 165 | .321 | 135 | .536 | 141 | .560 | 42.1 | 6.8 | 6.35 | 6.46 |
| Cole Henry | Tor | sp | 25 | .703 | 70 | .257 | 53 | .445 | 56 | .471 | 13.2 | 4.5 | 4.01 | 4.15 |
| Tommy Henry* | LAA | sp | 27 | .827 | 58 | .328 | 45 | .517 | 45 | .517 | 13.5 | 6.5 | 5.86 | 6.40 |
| Carlos Hernandez | ChN | mr | 28 | .629 | 516 | .266 | 317 | .387 | 327 | .399 | 79.7 | 3.7 | 3.31 | 3.23 |
| Daysbel Hernandez | | mr | 28 | .806 | 131 | .344 | 112 | .491 | 115 | .504 | 32.4 | 5.8 | 5.18 | 5.55 |
| Tim Herrin* | | mr | 28 | .735 | 223 | .341 | 163 | .449 | 166 | .457 | 45.2 | 5.1 | 4.65 | 4.72 |
| Jordan Hicks | SF | mr | 28 | .787 | 246 | .325 | 198 | .488 | 202 | .498 | 55.1 | 5.5 | 5.05 | 5.71 |
| Jaden Hill | | mr | 25 | .864 | 115 | .287 | 99 | .518 | 107 | .560 | 32.4 | 7.1 | 6.46 | 6.59 |
| Sean Hjelle | SF | mr | 28 | .711 | 322 | .301 | 194 | .422 | 202 | .439 | 55.4 | 4.7 | 4.34 | 4.22 |
| Porter Hodge | Was | mr | 24 | .807 | 131 | .313 | 112 | .511 | 114 | .521 | 28.2 | 5.0 | 4.48 | 5.35 |
| Bryan Hoeing | | mr | 28 | .680 | 408 | .282 | 245 | .421 | 248 | .426 | 61.8 | 3.9 | 3.54 | 3.34 |
| Jeff Hoffman | Min | mr | 32 | .635 | 196 | .255 | 143 | .404 | 148 | .418 | 33.2 | 3.4 | 3.13 | 3.02 |
| Andrew Hoffmann | Hou | sp | 25 | .735 | 241 | .274 | 158 | .459 | 160 | .465 | 45.3 | 5.1 | 4.62 | 4.33 |
| Gunnar Hoglund | Sac | sp | 25 | .937 | 67 | .313 | 56 | .596 | 56 | .596 | 17.7 | 7.7 | 7.05 | 7.29 |
| Colin Holderman | Bal | mr | 29 | .775 | 223 | .305 | 171 | .483 | 174 | .492 | 50.2 | 5.7 | 5.21 | 5.37 |
| Grant Holman | KC | mr | 25 | .573 | 67 | .269 | 31 | .344 | 31 | .344 | 7.0 | 2.7 | 2.46 | 2.20 |
| Clay Holmes | Sac | sp | 32 | .736 | 547 | .327 | 329 | .436 | 333 | .442 | 94.4 | 4.9 | 4.42 | 4.45 |
| Grant Holmes | Mia | mr | 29 | .626 | 154 | .273 | 83 | .369 | 88 | .391 | 19.7 | 3.2 | 2.97 | 2.93 |
| Tyler Holton* | Cle | mr | 29 | .630 | 262 | .252 | 151 | .388 | 156 | .401 | 32.5 | 3.0 | 2.66 | 2.77 |
| Cade Horton | Tam | sp | 23 | .689 | 248 | .290 | 156 | .413 | 164 | .434 | 43.7 | 4.3 | 3.91 | 3.59 |
| Tanner Houck | LAN | sp | 29 | .667 | 250 | .260 | 150 | .407 | 157 | .425 | 39.0 | 4.0 | 3.69 | 3.62 |
| Adrian Houser | StL | sp | 32 | .797 | 120 | .267 | 89 | .514 | 89 | .514 | 26.2 | 6.2 | 5.49 | 5.29 |
| Bryan Hudson* | Col | mr | 28 | .655 | 216 | .306 | 141 | .409 | 142 | .412 | 33.7 | 3.6 | 3.26 | 3.14 |
| Brandon Hughes* | NYN | mr | 29 | .609 | 56 | .250 | 43 | .394 | 45 | .413 | 9.0 | 3.0 | 2.64 | 2.45 |
| K.C. Hunt | Bos | sp | 24 | .634 | 317 | .268 | 203 | .404 | 204 | .406 | 51.4 | 3.9 | 3.47 | 3.02 |
| Brant Hurter* | ChN | sp | 26 | .728 | 571 | .299 | 345 | .436 | 357 | .451 | 94.5 | 4.6 | 4.08 | 4.05 |
| Raisel Iglesias | | cl | 35 | .678 | 210 | .262 | 152 | .439 | 155 | .448 | 35.2 | 3.7 | 3.26 | 2.78 |
| Shota Imanaga* | Col | sp | 31 | .731 | 444 | .320 | 281 | .442 | 288 | .453 | 74.5 | 4.4 | 4.00 | 4.04 |
| Jairo Iriarte | Col | sp | 23 | .664 | 89 | .258 | 53 | .411 | 55 | .426 | 12.9 | 3.7 | 3.33 | 3.23 |
| Cole Irvin* | | sp | 31 | .659 | 250 | .260 | 136 | .391 | 142 | .408 | 35.3 | 3.8 | 3.49 | 3.21 |
| Jake Irvin | | sp | 28 | .802 | 236 | .305 | 164 | .497 | 167 | .506 | 44.9 | 5.3 | 4.85 | 4.92 |
| Luke Jackson | Bal | mr | 33 | .711 | 204 | .289 | 156 | .448 | 159 | .457 | 40.9 | 4.6 | 4.16 | 4.30 |
| Alek Jacob | Pit | mr | 27 | .684 | 217 | .290 | 139 | .419 | 143 | .431 | 34.2 | 3.9 | 3.51 | 3.65 |
| Drey Jameson | Was | sp | 27 | .680 | 531 | .277 | 329 | .419 | 339 | .432 | 83.0 | 3.9 | 3.51 | 3.28 |
| Kenley Jansen | Tam | cl | 37 | .541 | 191 | .246 | 108 | .333 | 112 | .346 | 26.0 | 3.0 | 2.69 | 2.17 |
| Cristian Javier | Min | sp | 28 | .691 | 62 | .306 | 38 | .422 | 38 | .422 | 10.2 | 4.5 | 3.89 | 4.13 |
| Griffin Jax | Mia | mr | 30 | .628 | 182 | .313 | 107 | .381 | 109 | .388 | 26.3 | 3.5 | 3.09 | 2.54 |
| Jackson Jobe | SF | sp | 22 | .767 | 223 | .296 | 157 | .467 | 164 | .488 | 45.2 | 5.1 | 4.68 | 4.52 |
| Pierce Johnson | Mil | mr | 34 | .744 | 185 | .297 | 150 | .462 | 158 | .486 | 37.8 | 4.4 | 4.01 | 4.16 |
| Seth Johnson | StL | sp | 26 | .824 | 87 | .253 | 71 | .526 | 73 | .541 | 20.9 | 6.4 | 5.70 | 5.31 |
| Ben Joyce | Sac | mr | 24 | .514 | 14 | .357 | 8 | .296 | 8 | .296 | 1.6 | 2.2 | 2.09 | 2.50 |
| Jakob Junis | Det | mr | 32 | .674 | 118 | .297 | 69 | .408 | 71 | .420 | 17.3 | 3.8 | 3.45 | 3.10 |
| Janson Junk | Tex | sp | 29 | .751 | 115 | .243 | 81 | .482 | 82 | .488 | 20.2 | 4.6 | 4.20 | 4.54 |
| Tommy Kahnle | | mr | 35 | .697 | 75 | .293 | 59 | .454 | 59 | .454 | 14.9 | 4.5 | 4.11 | 4.04 |
| James Karinchak | Min | mr | 29 | .708 | 70 | .300 | 45 | .405 | 50 | .450 | 12.9 | 4.7 | 4.30 | 4.38 |
| Mitch Keller | KC | sp | 29 | .649 | 567 | .265 | 325 | .386 | 345 | .410 | 82.2 | 3.6 | 3.26 | 3.07 |
| Kevin Kelly | | mr | 27 | .603 | 164 | .232 | 91 | .370 | 95 | .386 | 20.4 | 2.9 | 2.68 | 2.45 |
| Merrill Kelly | Det | sp | 36 | .802 | 346 | .275 | 270 | .518 | 272 | .522 | 74.8 | 5.6 | 5.00 | 5.00 |
| Zak Kent | KC | sp | 27 | .763 | 209 | .301 | 156 | .484 | 157 | .488 | 41.7 | 4.9 | 4.35 | 4.08 |
| Orion Kerkering | Bos | mr | 24 | .491 | 166 | .259 | 74 | .284 | 79 | .303 | 13.9 | 1.9 | 1.64 | 1.66 |
| Clayton Kershaw* | LAA | sp | 37 | .662 | 365 | .271 | 221 | .418 | 224 | .423 | 54.7 | 3.8 | 3.43 | 2.91 |
| Yusei Kikuchi* | NYN | sp | 34 | .624 | 458 | .301 | 295 | .388 | 299 | .393 | 69.6 | 3.3 | 3.01 | 2.72 |
| Craig Kimbrel | Cle | cl | 37 | .644 | 76 | .316 | 58 | .406 | 60 | .420 | 14.2 | 3.7 | 3.39 | 3.02 |
| Bryan King* | Tam | mr | 28 | .629 | 182 | .269 | 110 | .389 | 112 | .396 | 25.5 | 3.3 | 3.00 | 2.99 |
| John King* | KC | mr | 30 | .688 | 245 | .282 | 142 | .416 | 145 | .425 | 34.1 | 3.8 | 3.46 | 3.55 |
| Michael King | Tam | sp | 30 | .524 | 226 | .221 | 128 | .339 | 131 | .347 | 24.7 | 2.3 | 2.05 | 1.65 |
| George Kirby | Sea | sp | 27 | .670 | 366 | .301 | 216 | .402 | 223 | .415 | 55.8 | 3.8 | 3.46 | 3.21 |
| Andrew Kittredge | ChN | mr | 35 | .718 | 181 | .298 | 112 | .444 | 113 | .448 | 29.3 | 4.3 | 3.89 | 3.64 |
| George Klassen | Bos | sp | 23 | .883 | 15 | .333 | 12 | .545 | 12 | .545 | 3.9 | 7.6 | 6.37 | 7.41 |
| Jack Kochanowicz | StL | sp | 24 | .767 | 325 | .305 | 187 | .447 | 196 | .469 | 56.7 | 5.3 | 4.74 | 4.48 |
| Jared Koenig* | Tam | mr | 31 | .822 | 169 | .379 | 122 | .492 | 123 | .496 | 38.8 | 6.8 | 6.16 | 6.12 |
| Stephen Kolek | | mr | 28 | .736 | 164 | .335 | 103 | .433 | 107 | .450 | 30.4 | 5.1 | 4.50 | 4.38 |
| Michael Kopech | SF | mr | 29 | .200 | 6 | .167 | 1 | .100 | 1 | .100 | 0.1 | 0.3 | 0.27 | 0.25 |
| Dean Kremer | Det | sp | 29 | .761 | 460 | .287 | 323 | .473 | 334 | .489 | 87.1 | 4.9 | 4.47 | 4.39 |
| Ben Kudrna | | sp | 22 | 1.093 | 28 | .357 | 30 | .682 | 31 | .705 | 10.3 | 9.9 | 9.27 | 9.52 |
| Alex Lange | LAN | mr | 29 | .738 | 213 | .286 | 171 | .466 | 176 | .480 | 47.2 | 5.2 | 4.66 | 4.95 |
| Sauryn Lao | Sac | mr | 25 | .789 | 215 | .288 | 164 | .500 | 165 | .503 | 46.1 | 5.4 | 4.96 | 4.83 |
| Andry Lara | LAN | sp | 22 | .738 | 508 | .305 | 319 | .454 | 321 | .457 | 96.8 | 5.5 | 5.02 | 4.51 |
| Jhancarlos Lara | StL | sp | 22 | .907 | 43 | .372 | 42 | .560 | 43 | .573 | 12.1 | 7.0 | 6.13 | 7.70 |
| Jake Latz* | NYA | mr | 29 | .494 | 12 | .083 | 7 | .350 | 7 | .350 | 1.6 | 2.7 | 2.32 | 1.38 |
| Eric Lauer* | Tex | sp | 30 | .725 | 137 | .343 | 84 | .435 | 85 | .440 | 24.3 | 4.9 | 4.45 | 3.91 |
| Max Lazar | Phi | mr | 26 | .693 | 208 | .264 | 132 | .433 | 135 | .443 | 32.5 | 3.9 | 3.51 | 3.31 |
| Kyle Leahy | ChN | mr | 28 | .844 | 51 | .333 | 38 | .528 | 38 | .528 | 11.3 | 6.5 | 5.98 | 6.17 |
| Jordan Leasure | Sac | mr | 26 | .857 | 13 | .154 | 17 | .607 | 17 | .607 | 4.5 | 6.7 | 6.06 | 6.25 |
| Jose Leclerc | Pit | mr | 31 | .524 | 50 | .220 | 31 | .333 | 34 | .366 | 6.2 | 2.5 | 2.25 | 1.93 |
| Chase Lee | | mr | 26 | .829 | 148 | .345 | 123 | .519 | 124 | .523 | 38.1 | 6.6 | 6.01 | 5.88 |
| Dylan Lee* | Det | mr | 30 | .755 | 197 | .350 | 157 | .466 | 160 | .475 | 44.9 | 5.2 | 4.73 | 4.45 |
| Jack Leiter | SF | sp | 25 | .707 | 79 | .304 | 57 | .432 | 59 | .447 | 15.1 | 4.3 | 3.98 | 4.33 |
| Mark Jr. Leiter | | mr | 34 | .733 | 93 | .237 | 87 | .489 | 89 | .500 | 21.2 | 4.5 | 4.02 | 3.77 |
| Matthew Liberatore* | Cin | mr | 25 | .833 | 226 | .310 | 164 | .506 | 169 | .522 | 47.2 | 5.8 | 5.31 | 5.65 |
| Zack Littell | | sp | 29 | .807 | 322 | .332 | 224 | .489 | 231 | .504 | 64.1 | 5.4 | 4.90 | 4.84 |
| Brendon Little* | LAN | mr | 28 | .726 | 226 | .296 | 158 | .446 | 162 | .458 | 43.0 | 4.9 | 4.43 | 4.42 |
| Luke Little* | Col | mr | 24 | .709 | 158 | .285 | 116 | .439 | 123 | .466 | 30.4 | 4.4 | 4.06 | 3.74 |
| Ben Lively | Col | sp | 33 | 1.153 | 15 | .200 | 17 | .773 | 18 | .818 | 5.0 | 9.0 | 8.13 | 7.39 |
| Jonathan Loaisiga | Ari | mr | 30 | .680 | 120 | .342 | 67 | .381 | 71 | .403 | 18.9 | 4.2 | 3.82 | 3.72 |
| Ryan Lobus | ChA | mr | 24 | .795 | 113 | .239 | 93 | .520 | 96 | .536 | 25.4 | 5.4 | 4.98 | 4.51 |
| Nick Lodolo* | | sp | 27 | .726 | 352 | .284 | 266 | .443 | 284 | .473 | 73.9 | 4.8 | 4.36 | 4.23 |
| Jacob Lopez* | Tex | sp | 27 | .704 | 48 | .229 | 37 | .463 | 38 | .475 | 8.4 | 3.8 | 3.41 | 3.45 |
| Pablo Lopez | Tex | sp | 29 | .632 | 211 | .275 | 140 | .393 | 146 | .410 | 32.7 | 3.3 | 3.04 | 2.69 |
| Brad Lord | Sac | sp | 25 | .657 | 100 | .290 | 55 | .385 | 58 | .406 | 13.9 | 3.7 | 3.32 | 3.40 |
| Michael Lorenzen | | sp | 33 | .790 | 352 | .267 | 265 | .505 | 269 | .512 | 72.2 | 5.5 | 4.84 | 5.13 |
| Richard Lovelady* | ChN | mr | 29 | .628 | 431 | .290 | 227 | .372 | 236 | .387 | 57.1 | 3.4 | 3.09 | 2.62 |
| Seth Lugo | NYN | sp | 35 | .692 | 463 | .276 | 306 | .434 | 312 | .443 | 75.3 | 3.9 | 3.53 | 3.31 |
| Jesus Luzardo* | Tex | sp | 27 | .627 | 257 | .284 | 159 | .385 | 163 | .395 | 36.8 | 3.3 | 3.04 | 2.99 |
| Daniel Lynch* | Phi | sp | 28 | .517 | 22 | .182 | 11 | .355 | 11 | .355 | 2.1 | 2.3 | 2.08 | 1.46 |
| Tyler Mahle | Ari | sp | 30 | .565 | 192 | .260 | 101 | .348 | 102 | .352 | 22.3 | 2.8 | 2.53 | 2.39 |
| Alek Manoah | Sea | sp | 27 | .770 | 49 | .306 | 32 | .427 | 37 | .493 | 9.0 | 4.7 | 4.38 | 4.78 |
| Joe Mantiply* | Col | mr | 34 | .575 | 107 | .243 | 61 | .359 | 63 | .371 | 10.9 | 2.2 | 1.95 | 1.98 |
| Ron Marinaccio | ChA | mr | 29 | .726 | 231 | .277 | 188 | .461 | 195 | .478 | 52.2 | 5.2 | 4.68 | 4.64 |
| German Marquez | | sp | 30 | .622 | 281 | .281 | 150 | .375 | 153 | .382 | 34.9 | 3.2 | 2.90 | 2.90 |
| Yunior Marte | StL | sp | 21 | .919 | 68 | .265 | 61 | .592 | 63 | .612 | 19.3 | 8.0 | 7.20 | 6.81 |
| Chris Martin | ChN | mr | 39 | .597 | 154 | .325 | 79 | .351 | 79 | .351 | 19.9 | 3.2 | 2.90 | 2.32 |
| Davis Martin | SD | sp | 28 | .654 | 26 | .269 | 17 | .415 | 18 | .439 | 4.3 | 4.0 | 3.63 | 2.33 |
| Riley Martin* | NYA | mr | 27 | .651 | 47 | .298 | 27 | .386 | 28 | .400 | 7.4 | 4.3 | 3.92 | 4.01 |
| Justin Martinez | Tex | mr | 23 | .562 | 60 | .333 | 36 | .336 | 37 | .346 | 8.6 | 3.1 | 2.79 | 2.57 |
| Nick Martinez | Mil | mr | 34 | .647 | 539 | .310 | 296 | .379 | 306 | .391 | 77.0 | 3.6 | 3.33 | 3.17 |
| Quinn Mathews* | StL | sp | 24 | .689 | 369 | .309 | 244 | .420 | 251 | .432 | 68.2 | 4.6 | 4.19 | 3.92 |
| Phil Maton | NYN | mr | 32 | .622 | 128 | .281 | 74 | .372 | 79 | .397 | 18.2 | 3.4 | 3.04 | 2.58 |
| Yuki Matsui* | NYN | mr | 29 | .991 | 63 | .333 | 75 | .625 | 77 | .642 | 24.0 | 8.9 | 8.11 | 9.49 |
| Zebby Matthews | Was | sp | 25 | .617 | 75 | .267 | 42 | .385 | 42 | .385 | 8.4 | 2.6 | 2.42 | 2.07 |
| Isaac Mattson | Ari | mr | 29 | .899 | 27 | .407 | 23 | .535 | 23 | .535 | 7.0 | 7.0 | 6.32 | 8.17 |
| Steven Matz* | LAA | sp | 34 | .635 | 409 | .254 | 239 | .387 | 250 | .405 | 59.0 | 3.6 | 3.22 | 2.96 |
| Zach Maxwell | | mr | 24 | .711 | 119 | .277 | 95 | .459 | 95 | .459 | 24.3 | 4.7 | 4.22 | 4.38 |
| Dustin May | Was | sp | 27 | .576 | 509 | .224 | 292 | .358 | 308 | .377 | 66.4 | 2.9 | 2.67 | 2.42 |
| Adam Mazur | Tam | sp | 24 | .487 | 125 | .208 | 46 | .293 | 46 | .293 | 8.8 | 1.9 | 1.80 | 1.65 |
| Lance McCullers | Tex | sp | 31 | .667 | 214 | .280 | 136 | .415 | 138 | .421 | 33.5 | 3.9 | 3.54 | 3.77 |
| Chayce McDermott | LAN | sp | 26 | .737 | 448 | .257 | 360 | .477 | 366 | .485 | 96.8 | 5.0 | 4.49 | 4.31 |
| Griff McGarry | Bal | mr | 26 | .761 | 83 | .229 | 66 | .496 | 67 | .504 | 17.5 | 5.4 | 4.78 | 4.70 |
| Easton McGee | | sp | 27 | .885 | 82 | .366 | 60 | .517 | 63 | .543 | 20.4 | 7.3 | 6.69 | 6.50 |
| Michael McGreevy | ChA | sp | 24 | .812 | 550 | .333 | 394 | .500 | 400 | .508 | 117.4 | 5.9 | 5.40 | 5.28 |
| Nolan McLean | Atl | dh | 23 | .701 | 30 | .333 | 18 | .409 | 18 | .409 | 5.4 | 5.2 | 4.88 | 5.27 |
| Nick Mears | Phi | mr | 28 | .765 | 155 | .303 | 148 | .507 | 148 | .507 | 37.9 | 5.1 | 4.54 | 4.45 |
| Trevor Megill | | cl | 31 | .652 | 115 | .313 | 79 | .405 | 80 | .410 | 19.5 | 3.8 | 3.43 | 3.06 |
| Tylor Megill | NYN | sp | 29 | .913 | 76 | .289 | 76 | .589 | 77 | .597 | 23.1 | 7.3 | 6.59 | 6.84 |
| Cristian Mena | SD | sp | 22 | .757 | 223 | .296 | 161 | .474 | 163 | .479 | 47.0 | 5.6 | 5.03 | 5.08 |
| Julian Merryweather | | mr | 33 | .644 | 111 | .279 | 76 | .409 | 77 | .414 | 19.6 | 4.1 | 3.70 | 3.34 |
| Luis Mey | Phi | mr | 24 | 1.905 | 8 | .500 | 18 | 1.286 | 18 | 1.286 | 7.1 | 23.9 | 21.51 | 23.95 |
| Max Meyer | ChA | sp | 26 | .673 | 445 | .290 | 279 | .413 | 285 | .422 | 71.2 | 4.0 | 3.60 | 3.66 |
| Miles Mikolas | | sp | 36 | .937 | 301 | .346 | 245 | .592 | 247 | .597 | 80.1 | 7.9 | 7.08 | 6.80 |
| Bobby Miller | Bal | sp | 26 | .673 | 302 | .268 | 193 | .420 | 199 | .434 | 49.3 | 4.1 | 3.68 | 3.37 |
| Bryce Miller | | sp | 26 | .768 | 274 | .310 | 197 | .486 | 200 | .494 | 51.9 | 4.8 | 4.35 | 3.83 |
| Erik Miller* | Tor | mr | 27 | .815 | 182 | .352 | 154 | .510 | 155 | .513 | 47.1 | 6.6 | 5.99 | 5.86 |
| Jacob Miller | StL | sp | 21 | .864 | 84 | .345 | 61 | .526 | 62 | .534 | 21.5 | 8.0 | 7.48 | 6.97 |
| Mason Miller | Bos | cl | 26 | .668 | 202 | .322 | 147 | .413 | 151 | .424 | 35.5 | 3.7 | 3.33 | 3.27 |
| Shelby Miller | | mr | 34 | .700 | 140 | .221 | 101 | .453 | 105 | .471 | 24.7 | 4.1 | 3.70 | 3.36 |
| Tyson Miller | Mil | mr | 29 | .679 | 112 | .250 | 70 | .424 | 72 | .436 | 17.2 | 3.9 | 3.49 | 3.48 |
| Hoby Milner* | | mr | 34 | .663 | 193 | .295 | 101 | .384 | 106 | .403 | 26.9 | 3.9 | 3.49 | 3.41 |
| Camden Minacci | Cin | mr | 23 | .831 | 25 | .320 | 22 | .537 | 22 | .537 | 6.6 | 6.4 | 5.94 | 5.06 |
| A.J. Minter* | Was | mr | 31 | .648 | 72 | .333 | 60 | .411 | 61 | .418 | 14.1 | 3.8 | 3.43 | 3.82 |
| Andrew Misiaszek* | | mr | 27 | .846 | 69 | .290 | 62 | .539 | 63 | .548 | 16.3 | 5.7 | 5.15 | 6.18 |
| Jacob Misiorowski | Tex | sp | 23 | .893 | 50 | .280 | 53 | .515 | 61 | .592 | 18.3 | 8.5 | 7.40 | 8.60 |
| Casey Mize | KC | sp | 28 | .666 | 214 | .294 | 125 | .408 | 126 | .412 | 31.5 | 3.9 | 3.58 | 3.57 |
| Carmen Mlodzinski | KC | mr | 26 | .729 | 270 | .304 | 169 | .426 | 180 | .453 | 50.3 | 5.0 | 4.56 | 4.41 |
| Keider Montero | | sp | 24 | .937 | 123 | .341 | 103 | .585 | 105 | .597 | 35.2 | 8.6 | 7.58 | 7.22 |
| Mason Montgomery* | | sp | 25 | .672 | 209 | .273 | 131 | .415 | 134 | .424 | 34.5 | 4.1 | 3.76 | 3.47 |
| Michael Morales | StL | sp | 22 | 1.164 | 7 | .286 | 9 | .818 | 9 | .818 | 3.0 | 11.6 | 10.43 | 8.35 |
| Adrian Morejon* | Cle | mr | 26 | .700 | 195 | .323 | 134 | .432 | 136 | .439 | 36.0 | 4.5 | 4.17 | 3.89 |
| Dauri Moreta | Mil | mr | 29 | .891 | 65 | .308 | 51 | .548 | 52 | .559 | 16.0 | 7.1 | 6.47 | 6.29 |
| David Morgan | Col | mr | 25 | .681 | 22 | .364 | 11 | .379 | 11 | .379 | 4.2 | 5.6 | 5.31 | 3.63 |
| Eli Morgan | Det | mr | 29 | .788 | 83 | .313 | 61 | .500 | 61 | .500 | 18.2 | 5.9 | 5.39 | 5.04 |
| Andrew Morris | Cin | sp | 23 | .705 | 105 | .238 | 61 | .452 | 62 | .459 | 15.1 | 4.0 | 3.67 | 3.05 |
| Charlie Morton | | sp | 41 | .653 | 458 | .264 | 316 | .401 | 336 | .426 | 78.7 | 3.7 | 3.44 | 3.30 |
| Andres Munoz | Sea | cl | 26 | .599 | 209 | .282 | 140 | .375 | 144 | .386 | 32.7 | 3.2 | 2.90 | 2.62 |
| Penn Murfee | Pit | mr | 31 | .717 | 106 | .245 | 66 | .446 | 68 | .459 | 17.6 | 4.5 | 4.03 | 3.58 |
| Tobias Myers | Min | sp | 26 | .695 | 364 | .291 | 233 | .434 | 234 | .436 | 58.0 | 4.0 | 3.62 | 3.49 |
| Jack Neely | Hou | mr | 25 | .621 | 174 | .282 | 100 | .382 | 102 | .389 | 23.8 | 3.3 | 3.03 | 2.54 |
| Kyle Nelson* | Atl | mr | 28 | .618 | 101 | .228 | 61 | .401 | 61 | .401 | 13.3 | 3.1 | 2.83 | 2.68 |
| Ryne Nelson | Cin | sp | 27 | .801 | 557 | .309 | 391 | .497 | 394 | .501 | 108.1 | 5.3 | 4.81 | 5.17 |
| Kyle Nicolas | Atl | mr | 26 | .775 | 287 | .331 | 221 | .477 | 227 | .490 | 62.6 | 5.4 | 4.84 | 4.73 |
| Doug Nikhazy* | Was | sp | 25 | .583 | 44 | .205 | 31 | .383 | 32 | .395 | 6.2 | 2.7 | 2.43 | 2.35 |
| Aaron Nola | Min | sp | 32 | .639 | 278 | .270 | 162 | .399 | 164 | .404 | 36.7 | 3.2 | 2.94 | 2.65 |
| Dedniel Nunez | Tex | mr | 29 | .757 | 183 | .333 | 143 | .480 | 143 | .480 | 38.9 | 5.1 | 4.65 | 4.35 |
| Juan Nunez | Phi | sp | 29 | 1.333 | 3 | .333 | 6 | 1.000 | 6 | 1.000 | 2.0 | 13.5 | 12.15 | 9.96 |
| Riley O'Brien | ChA | mr | 30 | .789 | 224 | .308 | 184 | .497 | 187 | .505 | 48.6 | 5.1 | 4.63 | 4.98 |
| Bailey Ober | Phi | sp | 29 | .638 | 443 | .257 | 274 | .399 | 281 | .410 | 66.8 | 3.5 | 3.20 | 2.80 |
| Shohei Ohtani | Tex | dh | 30 | .729 | 230 | .217 | 191 | .473 | 198 | .490 | 48.0 | 4.5 | 4.09 | 4.03 |
| Steven Okert* | Bos | mr | 33 | .700 | 109 | .257 | 79 | .434 | 84 | .462 | 20.8 | 4.3 | 3.88 | 3.38 |
| Reese Olson | KC | sp | 25 | .576 | 261 | .264 | 144 | .356 | 147 | .364 | 32.9 | 2.9 | 2.65 | 2.28 |
| Oliver Ortega | Bal | mr | 28 | .663 | 309 | .311 | 199 | .407 | 202 | .413 | 51.5 | 4.0 | 3.60 | 3.37 |
| Luis L. Ortiz | SD | sp | 26 | .676 | 227 | .278 | 152 | .423 | 156 | .435 | 34.9 | 3.6 | 3.25 | 3.41 |
| Eric Orze | | mr | 27 | .776 | 102 | .343 | 66 | .462 | 68 | .476 | 20.0 | 5.6 | 5.07 | 4.70 |
| Johan Oviedo | Cle | sp | 27 | .576 | 92 | .283 | 49 | .343 | 51 | .357 | 11.2 | 2.8 | 2.58 | 2.65 |
| Chris Paddack | LAA | sp | 29 | .630 | 499 | .279 | 287 | .389 | 291 | .395 | 67.4 | 3.3 | 2.97 | 2.64 |
| Emilio Pagan | ChA | mr | 34 | .745 | 217 | .290 | 152 | .465 | 155 | .474 | 44.5 | 5.3 | 4.76 | 4.11 |
| Andrew Painter | Atl | sp | 22 | .714 | 132 | .295 | 95 | .459 | 95 | .459 | 23.7 | 4.3 | 3.92 | 3.54 |
| Daniel Palencia | Sea | mr | 25 | .724 | 254 | .280 | 207 | .468 | 210 | .475 | 52.7 | 4.6 | 4.18 | 4.16 |
| Andre Pallante | Min | sp | 26 | .725 | 338 | .290 | 207 | .442 | 210 | .449 | 58.9 | 5.0 | 4.46 | 4.35 |
| Peyton Pallette | SD | mr | 24 | .450 | 10 | .400 | 5 | .250 | 5 | .250 | 1.0 | 1.7 | 1.43 | 1.06 |
| Mitchell Parker* | Atl | sp | 25 | .737 | 303 | .333 | 223 | .461 | 223 | .461 | 59.1 | 4.7 | 4.21 | 4.17 |
| Joel Payamps | | mr | 31 | .580 | 218 | .257 | 121 | .360 | 123 | .366 | 26.1 | 2.8 | 2.51 | 2.32 |
| Nate Pearson | Hou | mr | 28 | .775 | 80 | .250 | 79 | .513 | 81 | .526 | 22.7 | 5.8 | 5.37 | 4.81 |
| Ethan Pecko | Hou | sp | 22 | .733 | 206 | .330 | 127 | .441 | 128 | .444 | 37.8 | 5.2 | 4.69 | 4.26 |
| Elvis Peguero | Det | mr | 28 | .759 | 272 | .309 | 172 | .447 | 180 | .468 | 52.3 | 5.5 | 5.11 | 4.96 |
| Walter Pennington* | NYA | mr | 27 | .551 | 73 | .274 | 37 | .330 | 38 | .339 | 7.6 | 2.5 | 2.23 | 2.36 |
| Ryan Pepiot | KC | sp | 27 | .693 | 421 | .297 | 290 | .424 | 302 | .442 | 79.2 | 4.5 | 4.02 | 3.73 |
| Freddy Peralta | Mia | sp | 29 | .687 | 466 | .285 | 340 | .435 | 345 | .442 | 83.4 | 4.0 | 3.60 | 3.62 |
| Wandy Peralta* | SD | mr | 33 | .684 | 63 | .254 | 45 | .429 | 47 | .448 | 11.7 | 4.4 | 3.99 | 4.40 |
| Angel Perdomo* | Mia | mr | 31 | .598 | 82 | .232 | 70 | .400 | 72 | .411 | 14.1 | 2.9 | 2.57 | 2.59 |
| Cionel Perez* | | mr | 29 | .724 | 120 | .275 | 80 | .462 | 80 | .462 | 20.6 | 4.6 | 4.28 | 4.23 |
| Eury Perez | Bal | sp | 22 | .723 | 291 | .265 | 215 | .466 | 217 | .471 | 57.1 | 4.7 | 4.39 | 4.23 |
| Martin Perez* | LAN | sp | 34 | .618 | 77 | .273 | 39 | .371 | 40 | .381 | 9.1 | 3.2 | 2.91 | 2.80 |
| Jack Perkins | ChA | sp | 25 | .758 | 138 | .246 | 100 | .478 | 103 | .493 | 26.5 | 4.8 | 4.40 | 4.42 |
| David Peterson* | Sac | sp | 29 | .700 | 357 | .289 | 233 | .432 | 239 | .443 | 56.7 | 3.9 | 3.57 | 3.69 |
| Chase Petty | ChA | sp | 22 | .866 | 133 | .308 | 113 | .557 | 114 | .562 | 34.1 | 6.9 | 6.33 | 6.03 |
| Brandon Pfaadt | Col | sp | 26 | .761 | 466 | .290 | 365 | .485 | 372 | .495 | 97.5 | 4.9 | 4.46 | 4.36 |
| Evan Phillips | Mil | cl | 30 | .597 | 25 | .320 | 13 | .351 | 13 | .351 | 3.1 | 3.3 | 3.05 | 3.35 |
| Tyler Phillips | Cle | sp | 27 | 1.078 | 13 | .385 | 12 | .706 | 12 | .706 | 4.3 | 11.7 | 10.53 | 6.89 |
| Nick Pivetta | Cle | sp | 32 | .826 | 321 | .380 | 271 | .513 | 274 | .519 | 81.7 | 6.2 | 5.53 | 5.13 |
| Drew Pomeranz* | Was | mr | 36 | .706 | 161 | .286 | 119 | .452 | 120 | .456 | 29.6 | 4.3 | 3.89 | 4.04 |
| Cody Poteet | NYN | sp | 30 | .571 | 123 | .211 | 64 | .360 | 66 | .371 | 14.2 | 2.8 | 2.58 | 2.16 |
| Cade Povich* | Bos | sp | 25 | .815 | 158 | .291 | 135 | .534 | 137 | .542 | 40.0 | 6.3 | 5.69 | 4.70 |
| Ryan Pressly | | mr | 36 | .702 | 135 | .296 | 86 | .428 | 89 | .443 | 21.4 | 3.9 | 3.57 | 3.45 |
| Quinn Priester | Ari | sp | 24 | .597 | 429 | .275 | 222 | .351 | 231 | .366 | 53.2 | 3.1 | 2.81 | 2.85 |
| A.J. Puk* | LAN | mr | 30 | .603 | 15 | .267 | 13 | .406 | 13 | .406 | 3.0 | 3.5 | 3.28 | 2.98 |
| Jose Quijada* | | mr | 29 | .741 | 76 | .355 | 59 | .450 | 60 | .458 | 17.5 | 5.4 | 4.84 | 4.32 |
| Jose Quintana* | Pit | sp | 36 | .795 | 284 | .349 | 185 | .470 | 189 | .480 | 59.9 | 6.3 | 5.62 | 5.28 |
| Cole Ragans* | Was | sp | 27 | .624 | 269 | .275 | 158 | .384 | 161 | .392 | 35.3 | 3.1 | 2.81 | 2.85 |
| Brooks Raley* | Mia | mr | 37 | .596 | 32 | .281 | 20 | .377 | 20 | .377 | 3.8 | 2.5 | 2.26 | 2.50 |
| Drew Rasmussen | Bos | sp | 29 | .631 | 483 | .290 | 290 | .386 | 299 | .398 | 71.4 | 3.5 | 3.16 | 2.78 |
| Dylan Ray | StL | sp | 24 | .831 | 370 | .343 | 280 | .508 | 285 | .517 | 91.9 | 7.0 | 6.29 | 6.08 |
| Robbie Ray* | Pit | sp | 33 | .676 | 415 | .243 | 294 | .436 | 300 | .444 | 74.4 | 4.1 | 3.76 | 3.37 |
| Sean Reid-Foley | Atl | mr | 29 | 1.043 | 38 | .474 | 42 | .646 | 42 | .646 | 15.9 | 11.9 | 10.44 | 10.50 |
| Patrick Reilly | StL | sp | 23 | .473 | 72 | .167 | 37 | .322 | 37 | .322 | 6.7 | 2.1 | 1.86 | 1.59 |
| Eric Reyzelman | | mr | 24 | .778 | 94 | .287 | 75 | .487 | 78 | .506 | 22.1 | 5.6 | 5.18 | 4.68 |
| Trevor Richards | NYN | mr | 32 | .594 | 195 | .205 | 135 | .396 | 138 | .405 | 29.7 | 3.2 | 2.87 | 2.54 |
| Lyon Richardson | NYA | sp | 25 | .752 | 53 | .302 | 48 | .466 | 51 | .495 | 14.5 | 5.7 | 5.11 | 4.99 |
| Ethan Roberts | Sac | mr | 27 | .730 | 216 | .296 | 143 | .433 | 152 | .461 | 38.2 | 4.4 | 3.99 | 4.20 |
| David Robertson | Mil | mr | 40 | .503 | 61 | .230 | 31 | .316 | 31 | .316 | 5.7 | 2.0 | 1.80 | 1.78 |
| Tekoah Roby | Sac | sp | 23 | 1.070 | 44 | .455 | 38 | .633 | 39 | .650 | 16.1 | 12.4 | 11.51 | 10.35 |
| Joe Rock* | Cle | sp | 24 | .821 | 87 | .333 | 70 | .515 | 71 | .522 | 20.7 | 6.1 | 5.52 | 5.33 |
| Kumar Rocker | SD | sp | 25 | .674 | 284 | .292 | 189 | .425 | 190 | .427 | 49.9 | 4.2 | 3.76 | 3.25 |
| Carlos Rodon* | | sp | 32 | .673 | 472 | .320 | 320 | .414 | 325 | .420 | 82.2 | 4.0 | 3.60 | 3.47 |
| Carlos F. Rodriguez | | sp | 23 | .710 | 246 | .276 | 167 | .447 | 170 | .455 | 42.9 | 4.4 | 3.93 | 3.98 |
| Eduardo Rodriguez* | Min | sp | 32 | .718 | 445 | .308 | 293 | .448 | 293 | .448 | 75.8 | 4.4 | 4.00 | 3.90 |
| Manuel Rodriguez | Pit | mr | 28 | .842 | 102 | .382 | 70 | .483 | 73 | .503 | 20.7 | 5.7 | 5.23 | 6.55 |
| Randy Rodriguez | Hou | mr | 25 | .607 | 290 | .245 | 165 | .369 | 175 | .391 | 41.3 | 3.5 | 3.18 | 2.82 |
| Wilking Rodriguez | Det | mr | 35 | .761 | 93 | .323 | 66 | .462 | 67 | .469 | 19.4 | 5.5 | 5.01 | 5.14 |
| Yariel Rodriguez | ChN | sp | 28 | .598 | 117 | .256 | 73 | .358 | 80 | .392 | 17.0 | 3.2 | 2.88 | 3.27 |
| Taylor Rogers* | Ari | mr | 34 | .732 | 212 | .335 | 161 | .439 | 169 | .460 | 44.2 | 4.8 | 4.25 | 4.50 |
| Trevor Rogers* | SF | sp | 27 | .627 | 182 | .258 | 121 | .403 | 123 | .410 | 27.3 | 3.4 | 3.05 | 2.82 |
| Tyler Rogers | Cle | mr | 34 | .683 | 180 | .306 | 106 | .408 | 110 | .423 | 25.5 | 3.6 | 3.27 | 3.35 |
| Drew Rom* | Bos | sp | 25 | .802 | 17 | .412 | 9 | .429 | 9 | .429 | 3.3 | 6.9 | 6.25 | 6.07 |
| Jordan Romano | | cl | 32 | .672 | 181 | .354 | 127 | .410 | 129 | .416 | 33.5 | 4.1 | 3.75 | 3.30 |
| JoJo Romero* | Min | mr | 28 | .795 | 212 | .288 | 166 | .485 | 177 | .518 | 46.8 | 5.4 | 4.82 | 4.98 |
| Landen Roupp | | mr | 26 | .691 | 363 | .273 | 236 | .434 | 239 | .439 | 63.0 | 4.5 | 4.01 | 3.92 |
| Joe Ryan | Min | sp | 29 | .745 | 497 | .288 | 361 | .468 | 370 | .480 | 97.4 | 4.8 | 4.41 | 4.15 |
| Andrew Saalfrank* | Mia | mr | 27 | .637 | 125 | .240 | 88 | .421 | 88 | .421 | 19.7 | 3.5 | 3.17 | 3.23 |
| Erik Sabrowski* | Pit | mr | 27 | .770 | 35 | .371 | 32 | .492 | 32 | .492 | 8.1 | 4.7 | 4.20 | 3.76 |
| Chris Sale* | LAA | sp | 36 | .657 | 296 | .314 | 203 | .404 | 210 | .418 | 49.5 | 3.6 | 3.20 | 2.80 |
| Cristopher Sanchez* | Tam | sp | 28 | .706 | 520 | .290 | 325 | .434 | 333 | .445 | 85.7 | 4.3 | 3.92 | 3.52 |
| Nick Sandlin | Col | mr | 28 | .515 | 38 | .211 | 20 | .333 | 20 | .333 | 3.9 | 2.2 | 2.09 | 1.75 |
| Cole Sands | | mr | 27 | .605 | 292 | .250 | 192 | .384 | 198 | .396 | 42.1 | 3.0 | 2.73 | 2.49 |
| Dennis Santana | Bal | mr | 29 | .653 | 268 | .280 | 166 | .404 | 169 | .411 | 41.6 | 3.8 | 3.46 | 3.34 |
| Tony Santillan | Col | mr | 28 | .637 | 96 | .260 | 68 | .407 | 70 | .419 | 14.6 | 3.1 | 2.86 | 2.83 |
| Gregory Santos | LAA | mr | 25 | .721 | 20 | .300 | 13 | .394 | 15 | .455 | 3.1 | 3.5 | 3.26 | 5.02 |
| Roki Sasaki | Col | sp | 23 | .828 | 134 | .351 | 112 | .519 | 114 | .528 | 33.4 | 6.0 | 5.42 | 5.34 |
| Tayler Saucedo* | Mil | mr | 32 | .884 | 68 | .338 | 60 | .571 | 60 | .571 | 18.6 | 7.4 | 6.63 | 5.63 |
| Max Scherzer | Cle | sp | 40 | .589 | 249 | .249 | 146 | .367 | 152 | .382 | 32.8 | 3.0 | 2.71 | 2.36 |
| Cam Schlittler | | sp | 24 | .691 | 98 | .265 | 65 | .436 | 66 | .443 | 18.9 | 4.9 | 4.46 | 3.95 |
| Clarke Schmidt | | sp | 29 | .724 | 255 | .298 | 181 | .451 | 185 | .461 | 49.5 | 4.8 | 4.34 | 4.13 |
| John Schreiber | | mr | 31 | .656 | 149 | .262 | 94 | .414 | 95 | .419 | 20.2 | 3.2 | 2.83 | 3.00 |
| Noah Schultz* | ChA | sp | 21 | .673 | 264 | .265 | 156 | .407 | 163 | .426 | 43.3 | 4.3 | 3.94 | 3.70 |
| Spencer Schwellenbach | Atl | sp | 25 | .732 | 300 | .293 | 210 | .457 | 216 | .470 | 55.9 | 4.6 | 4.17 | 3.80 |
| Christian Scott | NYA | sp | 26 | .701 | 95 | .274 | 68 | .428 | 73 | .459 | 17.8 | 4.2 | 3.80 | 3.50 |
| Tanner Scott* | NYN | cl | 30 | .570 | 165 | .261 | 110 | .367 | 112 | .373 | 20.9 | 2.4 | 2.21 | 2.14 |
| Tayler Scott | Phi | mr | 33 | .709 | 105 | .333 | 73 | .432 | 74 | .438 | 20.5 | 4.7 | 4.29 | 4.25 |
| JP Sears* | Cin | sp | 29 | 1.000 | 6 | .500 | 7 | .636 | 7 | .636 | 1.4 | 4.1 | 3.69 | 6.98 |
| Kodai Senga | | sp | 32 | .735 | 323 | .260 | 286 | .481 | 290 | .488 | 70.2 | 4.5 | 4.02 | 4.13 |
| Luis Severino | Tex | sp | 31 | .846 | 276 | .315 | 208 | .520 | 215 | .538 | 62.4 | 6.2 | 5.66 | 5.54 |
| Paul Sewald | Cle | cl | 35 | .584 | 39 | .231 | 23 | .383 | 23 | .383 | 5.2 | 3.1 | 2.70 | 1.97 |
| Carson Seymour | | sp | 26 | .763 | 91 | .308 | 66 | .471 | 67 | .479 | 17.5 | 4.7 | 4.26 | 4.60 |
| Emmet Sheehan | Ari | sp | 25 | .615 | 218 | .266 | 139 | .384 | 143 | .395 | 32.1 | 3.3 | 2.93 | 2.79 |
| Brady Singer | LAN | sp | 28 | .666 | 595 | .274 | 368 | .412 | 378 | .423 | 87.7 | 3.6 | 3.28 | 3.25 |
| Paul Skenes | SF | sp | 23 | .762 | 454 | .341 | 349 | .478 | 351 | .481 | 98.6 | 5.3 | 4.75 | 4.52 |
| Tarik Skubal* | Tam | sp | 28 | .589 | 506 | .287 | 292 | .358 | 298 | .365 | 68.6 | 3.0 | 2.70 | 2.36 |
| Justin Slaten | Det | mr | 27 | .617 | 189 | .270 | 120 | .388 | 122 | .395 | 27.6 | 3.2 | 2.87 | 2.50 |
| Ethan Small* | NYN | mr | 28 | .982 | 11 | .364 | 13 | .650 | 13 | .650 | 4.7 | 9.7 | 9.43 | 9.01 |
| Cade Smith | LAA | mr | 26 | .572 | 188 | .330 | 115 | .336 | 120 | .351 | 26.5 | 2.8 | 2.56 | 2.55 |
| Shane Smith | SD | mr | 25 | .626 | 138 | .290 | 79 | .366 | 84 | .389 | 19.6 | 3.3 | 2.97 | 2.86 |
| AJ Smith-Shawver | Tex | sp | 22 | .783 | 85 | .282 | 68 | .500 | 69 | .507 | 20.6 | 6.0 | 5.32 | 4.48 |
| Blake Snell* | | sp | 32 | .611 | 169 | .272 | 122 | .390 | 125 | .399 | 29.6 | 3.6 | 3.20 | 2.95 |
| Robby Snelling* | Bal | sp | 21 | .737 | 327 | .297 | 210 | .447 | 216 | .460 | 61.0 | 5.1 | 4.68 | 4.47 |
| Anthony Solometo* | StL | sp | 22 | .589 | 49 | .224 | 27 | .370 | 28 | .384 | 6.2 | 3.1 | 2.80 | 2.44 |
| Jose Soriano | Cin | mr | 26 | .669 | 473 | .292 | 304 | .406 | 316 | .422 | 79.0 | 4.0 | 3.64 | 3.63 |
| Mike Soroka | Ari | sp | 27 | .862 | 133 | .286 | 118 | .551 | 121 | .565 | 33.4 | 6.3 | 5.80 | 6.07 |
| Gregory Soto* | Tam | mr | 30 | .603 | 147 | .306 | 97 | .370 | 101 | .385 | 22.7 | 3.2 | 2.93 | 2.67 |
| Bennett Sousa* | | mr | 30 | .748 | 95 | .253 | 78 | .476 | 81 | .494 | 21.3 | 5.0 | 4.61 | 4.61 |
| Gabe Speier* | Was | mr | 30 | .752 | 242 | .306 | 181 | .475 | 183 | .480 | 47.6 | 4.6 | 4.19 | 4.09 |
| Mitch Spence | SF | sp | 27 | .781 | 291 | .330 | 182 | .464 | 187 | .477 | 56.4 | 5.7 | 5.31 | 4.96 |
| Jeffrey Springs* | Bos | sp | 32 | .639 | 449 | .263 | 271 | .401 | 277 | .410 | 63.0 | 3.4 | 3.04 | 2.77 |
| Brandon Sproat | NYN | sp | 24 | .664 | 444 | .282 | 279 | .408 | 288 | .422 | 70.7 | 3.9 | 3.51 | 3.27 |
| Ryne Stanek | | mr | 33 | .879 | 141 | .348 | 125 | .561 | 125 | .561 | 36.6 | 6.5 | 6.01 | 5.93 |
| Justin Steele* | Tex | sp | 29 | .633 | 24 | .208 | 20 | .417 | 21 | .438 | 4.6 | 3.5 | 3.17 | 3.18 |
| Trevor Stephan | Pit | mr | 29 | .716 | 17 | .471 | 15 | .417 | 16 | .444 | 4.4 | 5.2 | 4.69 | 4.41 |
| Robert Stephenson | | mr | 32 | .706 | 14 | .357 | 16 | .485 | 16 | .485 | 3.8 | 4.2 | 3.81 | 2.76 |
| Brock Stewart | Tex | mr | 33 | .441 | 123 | .228 | 66 | .287 | 67 | .291 | 10.9 | 1.6 | 1.44 | 1.19 |
| Matt Strahm* | | mr | 33 | .589 | 290 | .283 | 188 | .368 | 194 | .380 | 42.6 | 3.0 | 2.68 | 2.25 |
| Hunter Stratton | Mia | mr | 28 | .759 | 95 | .316 | 79 | .488 | 79 | .488 | 20.6 | 5.1 | 4.59 | 4.94 |
| Spencer Strider | Sea | sp | 26 | .570 | 309 | .304 | 185 | .340 | 192 | .353 | 42.4 | 2.8 | 2.49 | 2.37 |
| Marcus Stroman | Pit | sp | 34 | .740 | 117 | .316 | 76 | .452 | 76 | .452 | 23.2 | 5.4 | 4.98 | 4.40 |
| Tyler Stuart | SD | sp | 25 | .726 | 58 | .276 | 33 | .434 | 34 | .447 | 9.4 | 4.8 | 4.29 | 4.28 |
| Jose Suarez* | LAA | sp | 27 | .827 | 41 | .366 | 35 | .507 | 36 | .522 | 11.0 | 6.8 | 5.94 | 5.98 |
| Ranger Suarez* | ChN | sp | 29 | .617 | 486 | .261 | 273 | .385 | 276 | .389 | 61.0 | 3.1 | 2.81 | 2.69 |
| Robert Suarez | Tam | cl | 34 | .701 | 212 | .321 | 147 | .426 | 152 | .441 | 39.9 | 4.5 | 3.99 | 3.84 |
| Tomoyuki Sugano | ChN | sp | 35 | .351 | 25 | .160 | 6 | .207 | 6 | .207 | 0.7 | 0.8 | 0.73 | 0.73 |
| Brent Suter* | LAN | mr | 35 | .661 | 270 | .274 | 147 | .390 | 154 | .408 | 40.0 | 4.0 | 3.64 | 3.37 |
| Erik Swanson | Tor | mr | 31 | .642 | 23 | .348 | 15 | .395 | 15 | .395 | 4.3 | 4.1 | 3.87 | 2.88 |
| Jameson Taillon | Tam | sp | 33 | .687 | 375 | .280 | 230 | .433 | 230 | .433 | 59.8 | 4.2 | 3.79 | 3.35 |
| Dillon Tate | Tex | mr | 31 | .594 | 30 | .367 | 15 | .326 | 15 | .326 | 4.1 | 3.4 | 3.14 | 3.44 |
| Troy Taylor | SF | mr | 23 | .926 | 152 | .375 | 147 | .572 | 151 | .588 | 47.8 | 8.0 | 7.35 | 7.32 |
| Kai-Wei Teng | Hou | sp | 26 | 1.047 | 69 | .362 | 61 | .649 | 62 | .660 | 22.6 | 10.5 | 9.48 | 9.01 |
| Emiliano Teodo | Tex | sp | 24 | .347 | 7 | .143 | 1 | .111 | 2 | .222 | 0.3 | 1.1 | 0.97 | 1.08 |
| Caleb Thielbar* | | mr | 38 | .822 | 165 | .370 | 146 | .520 | 147 | .523 | 43.3 | 6.3 | 5.66 | 5.42 |
| Keegan Thompson | Det | mr | 30 | .628 | 160 | .250 | 115 | .401 | 119 | .415 | 25.9 | 3.3 | 2.94 | 2.90 |
| Ryan Thompson | Bos | mr | 33 | .616 | 203 | .246 | 112 | .381 | 115 | .391 | 25.8 | 3.2 | 2.85 | 2.71 |
| Trent Thornton | Mil | mr | 31 | .717 | 106 | .292 | 67 | .447 | 68 | .453 | 17.9 | 4.5 | 3.92 | 3.29 |
| Blade Tidwell | Mil | sp | 24 | 1.071 | 25 | .200 | 31 | .756 | 31 | .756 | 8.4 | 7.8 | 7.00 | 7.59 |
| Jesus Tinoco | Atl | mr | 30 | .627 | 79 | .177 | 55 | .417 | 57 | .432 | 12.3 | 3.4 | 3.08 | 2.73 |
| Jonah Tong | Bos | sp | 22 | .819 | 21 | .333 | 21 | .538 | 21 | .538 | 6.0 | 6.0 | 5.43 | 5.17 |
| Michael Tonkin | NYA | mr | 35 | .770 | 58 | .293 | 37 | .457 | 39 | .481 | 10.6 | 5.3 | 4.88 | 5.53 |
| Justin Topa | | mr | 34 | .604 | 149 | .289 | 82 | .357 | 86 | .374 | 18.7 | 3.0 | 2.69 | 2.73 |
| Blake Treinen | | mr | 37 | .754 | 52 | .365 | 33 | .452 | 33 | .452 | 11.0 | 6.2 | 6.08 | 5.12 |
| Edwin Uceta | | mr | 27 | .500 | 226 | .208 | 126 | .321 | 130 | .332 | 25.6 | 2.3 | 2.11 | 1.78 |
| Miguel Ullola | StL | sp | 23 | .813 | 297 | .316 | 238 | .505 | 243 | .516 | 73.2 | 6.5 | 5.83 | 5.83 |
| Abner Uribe | Sea | mr | 25 | .482 | 128 | .203 | 82 | .308 | 90 | .338 | 15.5 | 2.1 | 1.89 | 1.92 |
| Jose Urquidy | Cle | sp | 30 | 1.196 | 6 | .667 | 5 | .625 | 5 | .625 | 3.0 | 26.9 | 24.20 | 27.72 |
| Framber Valdez* | LAA | sp | 31 | .634 | 546 | .278 | 348 | .399 | 353 | .405 | 76.0 | 3.1 | 2.85 | 2.84 |
| CJ Van Eyk | LAN | sp | 26 | .901 | 489 | .337 | 377 | .550 | 387 | .564 | 126.2 | 7.6 | 6.88 | 6.87 |
| Carlos Vargas | Sea | mr | 25 | .714 | 14 | .429 | 8 | .364 | 9 | .409 | 2.3 | 4.2 | 3.51 | 3.90 |
| Louie Varland | Atl | sp | 27 | .663 | 230 | .261 | 144 | .407 | 150 | .424 | 34.9 | 3.6 | 3.29 | 3.29 |
| Mike Vasil | SD | sp | 25 | .592 | 123 | .244 | 65 | .348 | 70 | .374 | 16.4 | 3.2 | 2.98 | 2.56 |
| Randy Vasquez | NYA | sp | 26 | .730 | 299 | .294 | 198 | .445 | 203 | .456 | 57.1 | 5.0 | 4.52 | 4.23 |
| Justin Verlander | | sp | 42 | .702 | 351 | .282 | 213 | .433 | 218 | .443 | 57.9 | 4.4 | 4.03 | 3.49 |
| Alex Vesia* | Atl | mr | 29 | .755 | 164 | .360 | 137 | .472 | 139 | .479 | 39.3 | 5.5 | 5.00 | 4.49 |
| Will Vest | Sac | mr | 30 | .592 | 213 | .268 | 117 | .366 | 119 | .372 | 25.7 | 2.9 | 2.64 | 2.41 |
| Victor Vodnik | LAA | mr | 25 | .647 | 83 | .241 | 58 | .411 | 60 | .426 | 12.7 | 3.3 | 3.00 | 3.32 |
| Michael Wacha | | sp | 33 | .799 | 468 | .344 | 327 | .484 | 332 | .492 | 94.7 | 5.5 | 4.99 | 5.11 |
| Hurston Waldrep | Atl | sp | 23 | .739 | 264 | .322 | 190 | .446 | 197 | .462 | 57.4 | 5.6 | 5.05 | 5.23 |
| Josh Walker* | Cin | mr | 30 | .656 | 115 | .278 | 68 | .389 | 71 | .406 | 16.9 | 3.6 | 3.26 | 3.38 |
| Ryan Walker | Phi | mr | 29 | .584 | 124 | .290 | 78 | .351 | 82 | .369 | 17.7 | 2.9 | 2.62 | 2.62 |
| Andrew Walters | Mia | mr | 24 | .396 | 8 | .125 | 5 | .313 | 5 | .313 | 0.6 | 1.6 | 1.41 | 2.01 |
| Will Warren | ChN | sp | 26 | .490 | 22 | .273 | 13 | .295 | 14 | .318 | 2.8 | 2.2 | 2.09 | 2.01 |
| Ryan Weathers* | Col | sp | 25 | .614 | 119 | .269 | 71 | .372 | 74 | .387 | 15.9 | 2.9 | 2.68 | 2.66 |
| Luke Weaver | Tam | mr | 31 | .704 | 205 | .307 | 154 | .443 | 157 | .451 | 40.7 | 4.5 | 4.10 | 3.93 |
| Jacob Webb | Mil | mr | 31 | .770 | 243 | .342 | 170 | .446 | 181 | .475 | 52.8 | 5.6 | 5.07 | 5.12 |
| Logan Webb | Sac | sp | 28 | .685 | 609 | .286 | 363 | .423 | 369 | .430 | 92.3 | 4.0 | 3.57 | 3.26 |
| Greg Weissert | Mia | mr | 30 | .671 | 185 | .270 | 122 | .414 | 126 | .427 | 32.4 | 4.2 | 3.84 | 3.70 |
| Tyler Wells | NYA | sp | 30 | .819 | 110 | .282 | 76 | .517 | 77 | .524 | 21.1 | 5.4 | 4.87 | 4.59 |
| Hayden Wesneski | NYA | mr | 27 | .539 | 158 | .203 | 87 | .351 | 89 | .359 | 18.0 | 2.6 | 2.36 | 2.01 |
| Cameron Weston | Tor | sp | 24 | .780 | 246 | .317 | 184 | .484 | 189 | .497 | 53.0 | 5.5 | 5.01 | 4.74 |
| Zack Wheeler | Phi | sp | 35 | .634 | 474 | .278 | 291 | .396 | 296 | .403 | 70.5 | 3.5 | 3.22 | 2.86 |
| Carson Whisenhunt* | KC | sp | 24 | .743 | 146 | .301 | 104 | .475 | 105 | .479 | 28.6 | 5.0 | 4.51 | 3.83 |
| Forrest Whitley | Cin | mr | 27 | .518 | 30 | .167 | 18 | .327 | 20 | .364 | 3.3 | 2.2 | 1.94 | 2.16 |
| Garrett Whitlock | Sac | mr | 29 | .665 | 523 | .298 | 326 | .410 | 331 | .416 | 81.1 | 3.7 | 3.34 | 3.05 |
| Jordan Wicks* | | sp | 25 | 1.124 | 20 | .350 | 25 | .714 | 25 | .714 | 9.2 | 12.4 | 12.37 | 12.37 |
| Nathan Wiles | Bal | mr | 26 | .848 | 118 | .280 | 82 | .547 | 82 | .547 | 23.2 | 5.9 | 5.47 | 5.33 |
| Devin Williams | Min | cl | 30 | .439 | 136 | .257 | 66 | .267 | 67 | .271 | 12.6 | 1.8 | 1.59 | 1.42 |
| Gavin Williams | Ari | sp | 25 | .657 | 471 | .278 | 293 | .408 | 298 | .414 | 71.9 | 3.7 | 3.35 | 3.17 |
| Allan Winans | SD | sp | 29 | .689 | 250 | .276 | 143 | .418 | 148 | .433 | 39.2 | 4.4 | 4.00 | 3.51 |
| Josh Winckowski | KC | mr | 27 | .624 | 239 | .255 | 127 | .388 | 128 | .391 | 30.4 | 3.3 | 3.05 | 2.55 |
| Keaton Winn | SF | sp | 27 | .232 | 12 | .167 | 3 | .136 | 3 | .136 | 0.4 | 0.5 | 0.48 | 0.41 |
| Bryan Woo | Pit | sp | 25 | .650 | 525 | .267 | 300 | .402 | 307 | .412 | 73.3 | 3.5 | 3.17 | 2.74 |
| Brandon Woodruff | Bos | sp | 32 | .639 | 215 | .279 | 132 | .388 | 136 | .400 | 35.2 | 3.9 | 3.51 | 3.19 |
| Jaden Woods* | SF | mr | 23 | .808 | 121 | .347 | 72 | .468 | 74 | .481 | 24.7 | 6.7 | 6.12 | 5.80 |
| Simeon Woods Richardso | Pit | sp | 24 | .750 | 138 | .304 | 98 | .480 | 98 | .480 | 26.6 | 4.9 | 4.46 | 3.85 |
| Kyle Wright | Col | sp | 29 | .797 | 42 | .262 | 33 | .516 | 34 | .531 | 8.9 | 5.2 | 4.79 | 4.56 |
| Justin Wrobleski* | Atl | sp | 24 | .775 | 59 | .288 | 48 | .500 | 48 | .500 | 12.8 | 5.1 | 4.56 | 4.42 |
| Yoshinobu Yamamoto | Col | sp | 26 | .563 | 540 | .243 | 298 | .351 | 308 | .363 | 63.3 | 2.6 | 2.40 | 1.98 |
| Ryan Yarbrough* | NYA | mr | 33 | .763 | 359 | .237 | 257 | .482 | 268 | .503 | 72.1 | 5.3 | 4.82 | 4.45 |
| Kirby Yates | Min | cl | 38 | .664 | 142 | .310 | 99 | .399 | 105 | .423 | 25.8 | 4.0 | 3.61 | 3.67 |
| Craig Yoho | Bos | mr | 25 | .708 | 206 | .306 | 153 | .430 | 162 | .455 | 40.8 | 4.5 | 4.08 | 4.28 |
| Brandon Young | Mia | sp | 26 | .769 | 70 | .314 | 41 | .466 | 41 | .466 | 11.5 | 5.0 | 4.50 | 4.39 |
| Rob Zastryzny* | | mr | 33 | .750 | 206 | .286 | 141 | .467 | 143 | .474 | 39.8 | 5.1 | 4.63 | 4.23 |
| Ryan Zeferjahn | | mr | 27 | .636 | 247 | .267 | 153 | .387 | 161 | .408 | 36.8 | 3.5 | 3.23 | 3.18 |
| Angel Zerpa* | | mr | 25 | .895 | 108 | .370 | 83 | .550 | 84 | .556 | 28.1 | 7.9 | 7.12 | 6.79 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | PCH/G | STR% |
| Andrew Abbott* | Det | sp | 26 | 28 | 0 | .000 | 0 | 14 | .500 | 106 | 3.8 | 24 | 8 | .333 | 87.1 | .602 |
| Bryan Abreu | Sea | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 11 | .550 | 18.5 | .609 |
| Jason Adam | Ari | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 19.0 | .618 |
| Zach Agnos | NYA | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 26.2 | .606 |
| Keegan Akin* | Phi | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 17.4 | .649 |
| Jorge Alcala | | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 22.1 | .602 |
| Sandy Alcantara | Pit | sp | 29 | 31 | 3 | .097 | 1 | 23 | .742 | 155 | 5.0 | 11 | 4 | .364 | 106.7 | .640 |
| Sam Aldegheri* | Atl | sp | 23 | 4 | 0 | .000 | 0 | 1 | .250 | 17 | 4.3 | 3 | 1 | .333 | 86.3 | .574 |
| Franco Aleman | KC | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 8 | .364 | 19.0 | .594 |
| Scott Alexander* | NYN | mr | 35 | 3 | 0 | .000 | 0 | 0 | .000 | 8 | 2.7 | 9 | 4 | .444 | 22.5 | .640 |
| Tyler Alexander* | ChA | mr | 30 | 3 | 0 | .000 | 0 | 1 | .333 | 7 | 2.3 | 5 | 2 | .400 | 48.4 | .654 |
| Logan Allen* | Was | sp | 28 | 32 | 0 | .000 | 0 | 12 | .375 | 108 | 3.4 | 28 | 10 | .357 | 93.9 | .621 |
| Elvis Alvarado | Tex | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 20.6 | .606 |
| Jose Alvarado* | Ari | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 21.5 | .615 |
| Kyle Amendt | Atl | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 6 | .462 | 21.7 | .592 |
| Ian Anderson | NYA | sp | 27 | 10 | 0 | .000 | 0 | 2 | .200 | 38 | 3.8 | 17 | 5 | .294 | 51.2 | .609 |
| Tyler Anderson* | Tor | sp | 35 | 16 | 0 | .000 | 0 | 8 | .500 | 75 | 4.7 | 5 | 0 | .000 | 96.9 | .630 |
| Shawn Armstrong | Ari | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 6 | .545 | 18.3 | .626 |
| Spencer Arrighetti | Phi | sp | 25 | 4 | 0 | .000 | 0 | 2 | .500 | 18 | 4.5 | 0 | 0 | .000 | 87.5 | .603 |
| Aaron Ashby* | Sea | mr | 27 | 9 | 0 | .000 | 0 | 1 | .111 | 35 | 3.9 | 14 | 3 | .214 | 58.0 | .556 |
| Braxton Ashcraft | Atl | sp | 25 | 24 | 0 | .000 | 0 | 13 | .542 | 96 | 4.0 | 13 | 5 | .385 | 61.2 | .641 |
| Graham Ashcraft | Was | sp | 27 | 1 | 0 | .000 | 0 | 1 | 1.000 | 0 | 0.0 | 18 | 7 | .389 | 20.5 | .626 |
| Sam Bachman | Tor | sp | 25 | 1 | 0 | .000 | 0 | 1 | 1.000 | 8 | 8.0 | 12 | 3 | .250 | 21.4 | .588 |
| Henry Baez | Tor | sp | 22 | 10 | 0 | .000 | 0 | 0 | .000 | 42 | 4.2 | 9 | 0 | .000 | 76.1 | .621 |
| Bryan Baker | Col | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 | 21.2 | .599 |
| Tanner Banks* | SD | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 10 | .333 | 19.0 | .629 |
| Scott Barlow | ChN | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 8 | .348 | 20.5 | .578 |
| Mason Barnett | StL | sp | 24 | 32 | 0 | .000 | 0 | 13 | .406 | 103 | 3.2 | 29 | 6 | .207 | 85.3 | .602 |
| Chris Bassitt | Mil | sp | 36 | 33 | 1 | .030 | 1 | 10 | .303 | 200 | 6.1 | 30 | 5 | .167 | 94.6 | .589 |
| Brady Basso* | Min | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 0 | .000 | 17.1 | .659 |
| Felix Bautista | ChN | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 20.5 | .611 |
| Shane Baz | Bal | sp | 26 | 37 | 0 | .000 | 0 | 9 | .243 | 174 | 4.7 | 25 | 9 | .360 | 81.3 | .600 |
| Eduard Bazardo | Pit | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 15 | .405 | 20.1 | .631 |
| Tristan Beck | SF | mr | 29 | 5 | 1 | .200 | 1 | 2 | .400 | 16 | 3.2 | 19 | 5 | .263 | 38.9 | .626 |
| Ian Bedell | ChA | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 9 | .409 | 19.3 | .611 |
| David Bednar | LAA | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 16.5 | .635 |
| Jalen Beeks* | LAN | mr | 31 | 2 | 0 | .000 | 0 | 0 | .000 | 12 | 6.0 | 40 | 9 | .225 | 27.4 | .596 |
| Clayton Beeter | Col | sp | 26 | 20 | 0 | .000 | 0 | 2 | .100 | 83 | 4.2 | 17 | 5 | .294 | 80.2 | .587 |
| Nigel Belgrave | | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 20.9 | .559 |
| Brayan Bello | Mil | sp | 26 | 28 | 0 | .000 | 0 | 18 | .643 | 122 | 4.4 | 12 | 7 | .583 | 91.6 | .620 |
| Valente Bellozo | Tor | sp | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 9 | 4.5 | 13 | 1 | .077 | 25.2 | .628 |
| Anthony Bender | Mil | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 9 | .563 | 17.8 | .601 |
| Ryan Bergert | Hou | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 9 | .643 | 27.3 | .614 |
| Brennan Bernardino* | | mr | 33 | 2 | 0 | .000 | 0 | 0 | .000 | 14 | 7.0 | 21 | 2 | .095 | 19.4 | .611 |
| Jose Berrios | | sp | 31 | 24 | 1 | .042 | 0 | 14 | .583 | 107 | 4.5 | 16 | 11 | .688 | 72.3 | .635 |
| Prelander Berroa | SF | mr | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 9 | 3.0 | 15 | 4 | .267 | 39.3 | .573 |
| Tanner Bibee | Was | sp | 26 | 33 | 0 | .000 | 0 | 18 | .545 | 163 | 4.9 | 12 | 4 | .333 | 92.5 | .635 |
| Phil Bickford | ChN | mr | 29 | 25 | 0 | .000 | 0 | 9 | .360 | 139 | 5.6 | 11 | 1 | .091 | 62.8 | .638 |
| Osvaldo Bido | | sp | 29 | 27 | 0 | .000 | 0 | 9 | .333 | 113 | 4.2 | 22 | 7 | .318 | 86.7 | .583 |
| Shane Bieber | Hou | sp | 30 | 6 | 0 | .000 | 0 | 4 | .667 | 29 | 4.8 | 4 | 2 | .500 | 96.7 | .621 |
| Hayden Birdsong | Bos | sp | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 29.4 | .565 |
| Ronel Blanco | Col | sp | 31 | 2 | 0 | .000 | 0 | 2 | 1.000 | 11 | 5.5 | 18 | 8 | .444 | 32.5 | .596 |
| A.J. Blubaugh | | sp | 24 | 23 | 0 | .000 | 0 | 13 | .565 | 72 | 3.1 | 18 | 9 | .500 | 67.1 | .608 |
| Ryan Borucki* | LAN | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 | 24.2 | .573 |
| Matt Boyd* | Tex | sp | 34 | 26 | 0 | .000 | 0 | 13 | .500 | 147 | 5.7 | 10 | 2 | .200 | 83.5 | .636 |
| Joe Boyle | NYA | sp | 25 | 28 | 0 | .000 | 0 | 3 | .107 | 136 | 4.9 | 34 | 14 | .412 | 69.3 | .521 |
| Kyle Bradish | Bal | sp | 28 | 7 | 1 | .143 | 1 | 5 | .714 | 27 | 3.9 | 7 | 0 | .000 | 105.7 | .647 |
| Taj Bradley | | sp | 24 | 31 | 0 | .000 | 0 | 13 | .419 | 137 | 4.4 | 21 | 6 | .286 | 89.1 | .616 |
| Matt Brash | Col | mr | 27 | 15 | 0 | .000 | 0 | 4 | .267 | 75 | 5.0 | 9 | 1 | .111 | 50.0 | .589 |
| Ryan Brasier | Pit | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 | 15.2 | .636 |
| Mitch Bratt* | StL | sp | 21 | 1 | 0 | .000 | 0 | 1 | 1.000 | 1 | 1.0 | 44 | 11 | .250 | 16.1 | .624 |
| Lucas Braun | | sp | 23 | 6 | 0 | .000 | 0 | 1 | .167 | 15 | 2.5 | 5 | 1 | .200 | 51.1 | .618 |
| Huascar Brazoban | NYN | mr | 35 | 1 | 0 | .000 | 0 | 0 | .000 | 10 | 10.0 | 24 | 5 | .208 | 23.3 | .582 |
| John Brebbia | ChA | mr | 35 | 1 | 0 | .000 | 0 | 1 | 1.000 | 6 | 6.0 | 28 | 9 | .321 | 17.0 | .599 |
| Jhony Brito | ChA | mr | 27 | 23 | 0 | .000 | 0 | 16 | .696 | 88 | 3.8 | 8 | 2 | .250 | 93.1 | .645 |
| Ben Brown | Sea | sp | 25 | 32 | 0 | .000 | 0 | 6 | .188 | 130 | 4.1 | 17 | 8 | .471 | 86.1 | .598 |
| Hunter Brown | Mia | sp | 26 | 36 | 0 | .000 | 0 | 20 | .556 | 217 | 6.0 | 25 | 8 | .320 | 91.1 | .618 |
| Kris Bubic* | Tex | mr | 27 | 12 | 0 | .000 | 0 | 2 | .167 | 58 | 4.8 | 12 | 5 | .417 | 48.4 | .630 |
| Walker Buehler | Phi | sp | 30 | 28 | 0 | .000 | 0 | 16 | .571 | 123 | 4.4 | 12 | 2 | .167 | 88.2 | .636 |
| J.B. Bukauskas | LAN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 17.0 | .735 |
| Aaron Bummer* | | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 17.9 | .632 |
| Brock Burke* | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 3 | .125 | 25.4 | .607 |
| Sean Burke | LAA | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 20.1 | .607 |
| Corbin Burnes | Ari | sp | 30 | 15 | 1 | .067 | 1 | 9 | .600 | 56 | 3.7 | 12 | 7 | .583 | 97.3 | .633 |
| Tanner Burns | ChA | mr | 26 | 25 | 0 | .000 | 0 | 6 | .240 | 87 | 3.5 | 31 | 6 | .194 | 62.8 | .572 |
| Ryan Burr | KC | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 15.4 | .669 |
| Mike Burrows | Sea | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 17.1 | .642 |
| Jose Butto | | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 19 | 3 | .158 | 22.2 | .575 |
| Edward Cabrera | Atl | sp | 27 | 24 | 0 | .000 | 0 | 2 | .083 | 126 | 5.3 | 18 | 3 | .167 | 74.4 | .590 |
| Jean Cabrera | Tor | sp | 23 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 16 | 8 | .500 | 27.4 | .604 |
| Noah Cameron* | Cin | sp | 25 | 27 | 0 | .000 | 0 | 8 | .296 | 115 | 4.3 | 19 | 10 | .526 | 78.1 | .630 |
| Griffin Canning | StL | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 36 | 15 | .417 | 18.0 | .607 |
| Jonathan Cannon | SD | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 22.8 | .633 |
| Yennier Cano | ChN | mr | 31 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 16 | 12 | .750 | 23.5 | .625 |
| Joey Cantillo* | SF | sp | 25 | 22 | 0 | .000 | 0 | 4 | .182 | 97 | 4.4 | 21 | 12 | .571 | 80.6 | .585 |
| Ben Casparius | ChA | sp | 26 | 10 | 0 | .000 | 0 | 0 | .000 | 35 | 3.5 | 20 | 7 | .350 | 47.2 | .569 |
| Jose Castillo* | ChN | mr | 29 | 2 | 0 | .000 | 0 | 1 | .500 | 16 | 8.0 | 9 | 3 | .333 | 44.3 | .574 |
| Luis Castillo | Bos | sp | 32 | 33 | 1 | .030 | 1 | 27 | .818 | 187 | 5.7 | 15 | 9 | .600 | 97.3 | .636 |
| Miguel Castro | Min | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 | 23.3 | .595 |
| Cade Cavalli | Sac | sp | 26 | 25 | 1 | .040 | 1 | 7 | .280 | 97 | 3.9 | 17 | 5 | .294 | 83.7 | .595 |
| Dylan Cease | Mil | sp | 29 | 33 | 0 | .000 | 0 | 17 | .515 | 153 | 4.6 | 14 | 1 | .071 | 88.8 | .611 |
| Slade Cecconi | SD | sp | 26 | 24 | 1 | .042 | 1 | 15 | .625 | 125 | 5.2 | 16 | 2 | .125 | 90.4 | .631 |
| Andrew Chafin* | Sac | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 14.5 | .583 |
| Bubba Chandler | SF | sp | 22 | 12 | 0 | .000 | 0 | 5 | .417 | 69 | 5.8 | 9 | 3 | .333 | 74.6 | .591 |
| Aroldis Chapman* | LAA | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 3 | .086 | 21.0 | .577 |
| Jesse Chavez | ChA | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 20.4 | .590 |
| Po-Yu Chen | StL | sp | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 17.2 | .629 |
| Jack Choate* | ChN | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 17.0 | .529 |
| Marc Church | Mil | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 22.7 | .595 |
| Aaron Civale | Min | sp | 30 | 6 | 0 | .000 | 0 | 2 | .333 | 18 | 3.0 | 4 | 3 | .750 | 78.3 | .587 |
| Emmanuel Clase | Sea | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 19.7 | .645 |
| Garrett Cleavinger* | Ari | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 15 | .455 | 21.1 | .587 |
| Adisyn Coffey | Hou | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 21.9 | .591 |
| Roansy Contreras | Det | mr | 25 | 23 | 0 | .000 | 0 | 12 | .522 | 106 | 4.6 | 22 | 7 | .318 | 50.9 | .621 |
| Nestor Cortes* | | sp | 30 | 10 | 0 | .000 | 0 | 6 | .600 | 43 | 4.3 | 10 | 1 | .100 | 72.0 | .627 |
| Danny Coulombe* | Det | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 7 | .241 | 17.4 | .632 |
| Austin Cox* | ChA | mr | 28 | 3 | 0 | .000 | 0 | 1 | .333 | 12 | 4.0 | 3 | 0 | .000 | 50.3 | .585 |
| Cooper Criswell | Mil | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 19.2 | .634 |
| Garrett Crochet* | Cle | sp | 26 | 32 | 0 | .000 | 0 | 10 | .313 | 147 | 4.6 | 16 | 1 | .063 | 85.2 | .627 |
| Declan Cronin | Tam | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 21.5 | .625 |
| Fernando Cruz | Hou | mr | 35 | 25 | 0 | .000 | 0 | 5 | .200 | 132 | 5.3 | 21 | 5 | .238 | 89.3 | .593 |
| Yoniel Curet | Sac | sp | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 23.8 | .550 |
| Xzavion Curry | SF | sp | 26 | 8 | 0 | .000 | 0 | 4 | .500 | 25 | 3.1 | 8 | 4 | .500 | 64.4 | .638 |
| Caden Dana | NYA | sp | 21 | 4 | 0 | .000 | 0 | 2 | .500 | 7 | 1.8 | 1 | 0 | .000 | 89.3 | .644 |
| Davis Daniel | Phi | sp | 28 | 19 | 0 | .000 | 0 | 9 | .474 | 100 | 5.3 | 13 | 3 | .231 | 90.2 | .621 |
| Hagen Danner | Cin | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 22.8 | .664 |
| Yu Darvish | | sp | 38 | 11 | 0 | .000 | 0 | 4 | .364 | 42 | 3.8 | 5 | 2 | .400 | 87.7 | .635 |
| Duncan Davitt | StL | sp | 25 | 6 | 0 | .000 | 0 | 3 | .500 | 20 | 3.3 | 31 | 7 | .226 | 27.3 | .613 |
| Enyel de los Santos | Mil | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 3 | .188 | 19.3 | .606 |
| Yerry de los Santos | NYA | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 30.1 | .618 |
| Jacob deGrom | | sp | 37 | 32 | 0 | .000 | 0 | 9 | .281 | 206 | 6.4 | 12 | 2 | .167 | 82.3 | .649 |
| Reid Detmers* | | sp | 25 | 4 | 0 | .000 | 0 | 1 | .250 | 9 | 2.3 | 5 | 0 | .000 | 56.1 | .594 |
| Alexis Diaz | Det | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 20 | .541 | 22.8 | .576 |
| Edwin Diaz | LAA | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 3 | .231 | 20.4 | .628 |
| Miguel Diaz | | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 8 | .381 | 19.4 | .624 |
| Yilber Diaz | Hou | sp | 24 | 23 | 0 | .000 | 0 | 10 | .435 | 120 | 5.2 | 24 | 9 | .375 | 84.2 | .584 |
| Hunter Dobbins | Sea | sp | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 5 | 1.7 | 0 | 0 | .000 | 86.7 | .600 |
| Dylan Dodd* | Sac | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 15.9 | .650 |
| Chase Dollander | Ari | sp | 23 | 6 | 0 | .000 | 0 | 1 | .167 | 20 | 3.3 | 21 | 4 | .190 | 38.2 | .593 |
| Seranthony Dominguez | Was | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 | 19.8 | .580 |
| Camilo Doval | Cle | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 16.6 | .606 |
| Jack Dreyer* | KC | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 44 | 21 | .477 | 20.0 | .615 |
| Jhoan Duran | Sea | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 20.8 | .642 |
| Zach Eflin | | sp | 31 | 18 | 0 | .000 | 0 | 9 | .500 | 82 | 4.6 | 10 | 7 | .700 | 89.3 | .654 |
| Brandon Eisert* | Det | mr | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 17 | 6 | .353 | 22.6 | .619 |
| Bryce Elder | NYN | sp | 26 | 33 | 2 | .061 | 1 | 19 | .576 | 111 | 3.4 | 11 | 4 | .364 | 98.1 | .605 |
| Magnus Ellerts | Atl | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 36 | 12 | .333 | 19.0 | .590 |
| Mason Englert | Atl | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.0 | .737 |
| Nic Enright | Cin | mr | 28 | 7 | 0 | .000 | 0 | 0 | .000 | 29 | 4.1 | 20 | 4 | .200 | 31.1 | .617 |
| Nathan Eovaldi | Sac | sp | 35 | 12 | 1 | .083 | 1 | 8 | .667 | 44 | 3.7 | 5 | 0 | .000 | 94.3 | .643 |
| Lucas Erceg | LAN | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 19.5 | .611 |
| Carlos Estevez | | cl | 32 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 15 | 5 | .333 | 20.3 | .628 |
| Jeremiah Estrada | Sea | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 | 20.1 | .598 |
| Logan Evans | Tor | sp | 24 | 4 | 0 | .000 | 0 | 1 | .250 | 13 | 3.3 | 17 | 7 | .412 | 27.5 | .580 |
| Pete Fairbanks | ChN | cl | 31 | 3 | 0 | .000 | 0 | 0 | .000 | 14 | 4.7 | 10 | 4 | .400 | 26.1 | .624 |
| Bailey Falter* | KC | sp | 28 | 18 | 0 | .000 | 0 | 6 | .333 | 85 | 4.7 | 12 | 1 | .083 | 85.9 | .647 |
| Calvin Faucher | | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 9 | .273 | 19.2 | .590 |
| Erick Fedde | Tam | sp | 32 | 15 | 0 | .000 | 0 | 3 | .200 | 59 | 3.9 | 15 | 4 | .267 | 83.6 | .585 |
| Ryan Feltner | Mil | sp | 28 | 7 | 1 | .143 | 1 | 4 | .571 | 42 | 6.0 | 2 | 0 | .000 | 87.7 | .619 |
| Caleb Ferguson* | LAA | mr | 28 | 5 | 0 | .000 | 0 | 2 | .400 | 14 | 2.8 | 23 | 6 | .261 | 25.1 | .614 |
| Ryan Fernandez | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 8 | .421 | 22.0 | .598 |
| Jose A. Ferrer* | Hou | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 13 | .433 | 19.4 | .636 |
| David Festa | Hou | sp | 25 | 14 | 0 | .000 | 0 | 2 | .143 | 57 | 4.1 | 19 | 8 | .421 | 56.9 | .601 |
| Kyle Finnegan | NYN | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 25.2 | .606 |
| Braydon Fisher | LAN | mr | 24 | 5 | 0 | .000 | 0 | 0 | .000 | 26 | 5.2 | 25 | 14 | .560 | 24.2 | .579 |
| Jack Flaherty | | sp | 29 | 28 | 1 | .036 | 1 | 13 | .464 | 126 | 4.5 | 19 | 8 | .421 | 88.6 | .628 |
| Jose Fleury | StL | sp | 23 | 14 | 0 | .000 | 0 | 4 | .286 | 56 | 4.0 | 42 | 19 | .452 | 35.7 | .597 |
| Dylan Floro | Was | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 10 | .333 | 20.2 | .625 |
| Mason Fluharty* | | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 8 | .471 | 26.2 | .612 |
| Jason Foley | Sac | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 15.1 | .595 |
| J.P. France | KC | sp | 30 | 7 | 0 | .000 | 0 | 4 | .571 | 25 | 3.6 | 2 | 0 | .000 | 84.3 | .602 |
| Bowden Francis | Tex | sp | 29 | 12 | 1 | .083 | 0 | 7 | .583 | 79 | 6.6 | 3 | 0 | .000 | 92.9 | .670 |
| Max Fried* | Ari | sp | 31 | 35 | 2 | .057 | 1 | 19 | .543 | 157 | 4.5 | 21 | 10 | .476 | 99.7 | .622 |
| Kody Funderburk* | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 19.1 | .620 |
| Hunter Gaddis | Bos | mr | 27 | 18 | 0 | .000 | 0 | 8 | .444 | 70 | 3.9 | 21 | 7 | .333 | 47.1 | .638 |
| Matt Gage* | NYA | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 | 19.1 | .595 |
| Zac Gallen | Mia | sp | 29 | 36 | 1 | .028 | 1 | 23 | .639 | 196 | 5.4 | 17 | 4 | .235 | 98.8 | .619 |
| Brandyn Garcia* | Bal | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 10.0 | .500 |
| Luis A. Garcia | | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 5 | .179 | 18.8 | .642 |
| Robert Garcia* | Was | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 9 | .281 | 18.0 | .609 |
| Yimi Garcia | Hou | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 16.5 | .617 |
| Reed Garrett | NYN | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 11 | .268 | 20.9 | .601 |
| Robert Gasser* | Cin | sp | 26 | 5 | 0 | .000 | 0 | 2 | .400 | 33 | 6.6 | 4 | 2 | .500 | 84.4 | .604 |
| Kevin Gausman | Min | sp | 34 | 32 | 0 | .000 | 0 | 19 | .594 | 157 | 4.9 | 12 | 7 | .583 | 95.9 | .635 |
| Paul Gervase | | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 8 | .320 | 23.6 | .556 |
| Kyle Gibson | Bos | sp | 37 | 6 | 1 | .167 | 1 | 3 | .500 | 48 | 8.0 | 5 | 0 | .000 | 103.8 | .600 |
| Luis Gil | SD | sp | 27 | 8 | 0 | .000 | 0 | 1 | .125 | 47 | 5.9 | 2 | 1 | .500 | 81.8 | .621 |
| Logan Gilbert | Ari | sp | 28 | 25 | 0 | .000 | 0 | 14 | .560 | 119 | 4.8 | 14 | 4 | .286 | 92.9 | .641 |
| Kevin Ginkel | | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 6 | .462 | 18.8 | .637 |
| J.T. Ginn | | sp | 26 | 4 | 0 | .000 | 0 | 1 | .250 | 17 | 4.3 | 19 | 7 | .368 | 27.4 | .590 |
| Lucas Giolito | Mia | sp | 30 | 3 | 0 | .000 | 0 | 1 | .333 | 19 | 6.3 | 1 | 0 | .000 | 104.3 | .623 |
| Sawyer Gipson-Long | Mia | sp | 27 | 6 | 0 | .000 | 0 | 2 | .333 | 31 | 5.2 | 4 | 2 | .500 | 89.3 | .625 |
| Tyler Glasnow | Sea | sp | 31 | 21 | 0 | .000 | 0 | 12 | .571 | 78 | 3.7 | 10 | 5 | .500 | 92.1 | .630 |
| Yoendrys Gomez | SD | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 18.8 | .589 |
| Tony Gonsolin | Tex | sp | 31 | 7 | 0 | .000 | 0 | 4 | .571 | 31 | 4.4 | 1 | 0 | .000 | 80.0 | .650 |
| Colton Gordon* | | sp | 26 | 19 | 0 | .000 | 0 | 7 | .368 | 110 | 5.8 | 11 | 6 | .545 | 70.4 | .637 |
| MacKenzie Gore* | | sp | 26 | 28 | 0 | .000 | 0 | 8 | .286 | 149 | 5.3 | 14 | 4 | .286 | 85.6 | .611 |
| Gordon Graceffo | Min | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 20.8 | .585 |
| Andre Granillo | NYA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 25.6 | .561 |
| Kendall Graveman | NYN | mr | 34 | 2 | 0 | .000 | 0 | 0 | .000 | 8 | 4.0 | 7 | 0 | .000 | 31.2 | .591 |
| Jon Gray | Sac | sp | 33 | 5 | 0 | .000 | 0 | 4 | .800 | 20 | 4.0 | 2 | 1 | .500 | 97.8 | .628 |
| Sonny Gray | Phi | sp | 35 | 33 | 0 | .000 | 0 | 23 | .697 | 135 | 4.1 | 17 | 5 | .294 | 94.8 | .626 |
| Chad Green | ChN | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 21.9 | .638 |
| Hunter Greene | Col | sp | 25 | 11 | 0 | .000 | 0 | 4 | .364 | 56 | 5.1 | 3 | 1 | .333 | 97.5 | .615 |
| Sean Guenther* | Bal | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 31.0 | .613 |
| Luis Guerrero | | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 29.8 | .569 |
| Ryan Gusto | | sp | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 18 | 18.0 | 11 | 2 | .182 | 32.2 | .599 |
| Josh Hader* | | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 18.9 | .601 |
| Skylar Hales | Atl | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 24.5 | .629 |
| DL Hall* | Bal | sp | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 11 | 2 | .182 | 22.1 | .584 |
| Seth Halvorsen | Hou | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 0 | .000 | 19.4 | .604 |
| Ian Hamilton | Tex | mr | 30 | 20 | 0 | .000 | 0 | 7 | .350 | 98 | 4.9 | 13 | 2 | .154 | 58.9 | .596 |
| Emerson Hancock | Sea | sp | 26 | 4 | 0 | .000 | 0 | 1 | .250 | 21 | 5.3 | 4 | 0 | .000 | 91.5 | .577 |
| Brenan Hanifee | Det | mr | 27 | 36 | 1 | .028 | 1 | 19 | .528 | 149 | 4.1 | 16 | 6 | .375 | 92.4 | .625 |
| Landon Harper | Cin | mr | 24 | 1 | 0 | .000 | 0 | 1 | 1.000 | 5 | 5.0 | 1 | 0 | .000 | 29.0 | .661 |
| Thomas Harrington | Sea | sp | 23 | 26 | 0 | .000 | 0 | 10 | .385 | 118 | 4.5 | 17 | 4 | .235 | 81.3 | .618 |
| Hayden Harris* | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 15.0 | .511 |
| Kyle Harrison* | | sp | 23 | 27 | 0 | .000 | 0 | 8 | .296 | 95 | 3.5 | 22 | 4 | .182 | 67.2 | .622 |
| Kyle Hart* | Mil | sp | 32 | 29 | 0 | .000 | 0 | 15 | .517 | 154 | 5.3 | 19 | 3 | .158 | 79.4 | .645 |
| Grant Hartwig | NYN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 21.4 | .561 |
| Hunter Harvey | Hou | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 24.1 | .618 |
| Brent Headrick* | NYA | sp | 27 | 4 | 0 | .000 | 0 | 1 | .250 | 15 | 3.8 | 13 | 6 | .462 | 43.5 | .617 |
| Andrew Heaney* | StL | sp | 34 | 23 | 0 | .000 | 0 | 7 | .304 | 78 | 3.4 | 21 | 10 | .476 | 76.1 | .619 |
| Ryan Helsley | Col | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 21.2 | .601 |
| Logan Henderson | SF | sp | 23 | 23 | 0 | .000 | 0 | 7 | .304 | 83 | 3.6 | 24 | 5 | .208 | 56.8 | .626 |
| Liam Hendriks | ChN | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 21.5 | .593 |
| Edgardo Henriquez | Atl | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 7 | .636 | 22.8 | .567 |
| Ronny Henriquez | Tex | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 | 18.6 | .583 |
| Cole Henry | Tor | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 7 | .500 | 17.9 | .569 |
| Tommy Henry* | LAA | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 19.5 | .579 |
| Carlos Hernandez | ChN | mr | 28 | 34 | 0 | .000 | 0 | 16 | .471 | 138 | 4.1 | 19 | 2 | .105 | 92.9 | .601 |
| Daysbel Hernandez | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 9 | .281 | 21.4 | .573 |
| Tim Herrin* | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 43 | 12 | .279 | 16.9 | .601 |
| Jordan Hicks | SF | mr | 28 | 7 | 0 | .000 | 0 | 3 | .429 | 21 | 3.0 | 21 | 10 | .476 | 40.8 | .554 |
| Jaden Hill | | mr | 25 | 4 | 0 | .000 | 0 | 2 | .500 | 12 | 3.0 | 7 | 0 | .000 | 56.9 | .591 |
| Sean Hjelle | SF | mr | 28 | 4 | 0 | .000 | 0 | 2 | .500 | 10 | 2.5 | 23 | 7 | .304 | 33.1 | .606 |
| Porter Hodge | Was | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 24.6 | .565 |
| Bryan Hoeing | | mr | 28 | 21 | 0 | .000 | 0 | 11 | .524 | 70 | 3.3 | 16 | 7 | .438 | 87.1 | .629 |
| Jeff Hoffman | Min | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 3 | .200 | 21.1 | .619 |
| Andrew Hoffmann | Hou | sp | 25 | 16 | 0 | .000 | 0 | 3 | .188 | 65 | 4.1 | 15 | 6 | .400 | 68.7 | .596 |
| Gunnar Hoglund | Sac | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 16.6 | .623 |
| Colin Holderman | Bal | mr | 29 | 7 | 0 | .000 | 0 | 1 | .143 | 29 | 4.1 | 32 | 12 | .375 | 30.2 | .585 |
| Grant Holman | KC | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 4 | .800 | 17.4 | .645 |
| Clay Holmes | Sac | sp | 32 | 33 | 0 | .000 | 0 | 14 | .424 | 137 | 4.2 | 21 | 9 | .429 | 84.7 | .623 |
| Grant Holmes | Mia | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 17.4 | .630 |
| Tyler Holton* | Cle | mr | 29 | 7 | 0 | .000 | 0 | 2 | .286 | 34 | 4.9 | 27 | 10 | .370 | 24.6 | .646 |
| Cade Horton | Tam | sp | 23 | 17 | 0 | .000 | 0 | 7 | .412 | 94 | 5.5 | 4 | 1 | .250 | 81.1 | .628 |
| Tanner Houck | LAN | sp | 29 | 16 | 0 | .000 | 0 | 5 | .313 | 49 | 3.1 | 10 | 4 | .400 | 85.4 | .611 |
| Adrian Houser | StL | sp | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 7 | .538 | 22.4 | .599 |
| Bryan Hudson* | Col | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 14 | .412 | 19.2 | .623 |
| Brandon Hughes* | NYN | mr | 29 | 5 | 0 | .000 | 0 | 3 | .600 | 26 | 5.2 | 3 | 0 | .000 | 85.8 | .618 |
| K.C. Hunt | Bos | sp | 24 | 16 | 0 | .000 | 0 | 4 | .250 | 76 | 4.8 | 23 | 8 | .348 | 42.0 | .604 |
| Brant Hurter* | ChN | sp | 26 | 33 | 1 | .030 | 0 | 15 | .455 | 151 | 4.6 | 21 | 5 | .238 | 87.0 | .639 |
| Raisel Iglesias | | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 18.5 | .648 |
| Shota Imanaga* | Col | sp | 31 | 26 | 0 | .000 | 0 | 13 | .500 | 151 | 5.8 | 11 | 2 | .182 | 91.4 | .646 |
| Jairo Iriarte | Col | sp | 23 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 9 | 4 | .444 | 27.3 | .572 |
| Cole Irvin* | | sp | 31 | 6 | 0 | .000 | 0 | 5 | .833 | 17 | 2.8 | 12 | 4 | .333 | 34.0 | .625 |
| Jake Irvin | | sp | 28 | 13 | 0 | .000 | 0 | 5 | .385 | 41 | 3.2 | 8 | 3 | .375 | 94.4 | .625 |
| Luke Jackson | Bal | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 8 | .308 | 24.2 | .595 |
| Alek Jacob | Pit | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 4 | .154 | 22.0 | .589 |
| Drey Jameson | Was | sp | 27 | 32 | 1 | .031 | 1 | 18 | .563 | 140 | 4.4 | 18 | 2 | .111 | 90.6 | .606 |
| Kenley Jansen | Tam | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 9 | .273 | 16.8 | .601 |
| Cristian Javier | Min | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 21.9 | .573 |
| Griffin Jax | Mia | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 17.4 | .634 |
| Jackson Jobe | SF | sp | 22 | 13 | 0 | .000 | 0 | 3 | .231 | 54 | 4.2 | 7 | 3 | .429 | 80.4 | .637 |
| Pierce Johnson | Mil | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 10 | .370 | 19.6 | .597 |
| Seth Johnson | StL | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 21.4 | .551 |
| Ben Joyce | Sac | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 4 | 1.000 | 24.8 | .573 |
| Jakob Junis | Det | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 21.4 | .638 |
| Janson Junk | Tex | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 23.7 | .596 |
| Tommy Kahnle | | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 17.3 | .576 |
| James Karinchak | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 6 | .545 | 21.6 | .577 |
| Mitch Keller | KC | sp | 29 | 34 | 0 | .000 | 0 | 21 | .618 | 148 | 4.4 | 15 | 1 | .067 | 91.3 | .628 |
| Kevin Kelly | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 19.6 | .642 |
| Merrill Kelly | Det | sp | 36 | 20 | 0 | .000 | 0 | 8 | .400 | 84 | 4.2 | 18 | 4 | .222 | 89.3 | .622 |
| Zak Kent | KC | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 17.9 | .643 |
| Orion Kerkering | Bos | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 19.3 | .623 |
| Clayton Kershaw* | LAA | sp | 37 | 25 | 0 | .000 | 0 | 9 | .360 | 113 | 4.5 | 19 | 6 | .316 | 79.3 | .641 |
| Yusei Kikuchi* | NYN | sp | 34 | 32 | 1 | .031 | 1 | 16 | .500 | 151 | 4.7 | 17 | 5 | .294 | 90.7 | .641 |
| Craig Kimbrel | Cle | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 11 | .733 | 19.8 | .604 |
| Bryan King* | Tam | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 18.1 | .599 |
| John King* | KC | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 7 | .333 | 14.9 | .643 |
| Michael King | Tam | sp | 30 | 16 | 0 | .000 | 0 | 10 | .625 | 60 | 3.8 | 6 | 2 | .333 | 97.0 | .624 |
| George Kirby | Sea | sp | 27 | 23 | 0 | .000 | 0 | 13 | .565 | 95 | 4.1 | 16 | 2 | .125 | 87.0 | .654 |
| Andrew Kittredge | ChN | mr | 35 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 15 | 7 | .467 | 21.0 | .645 |
| George Klassen | Bos | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 0 | 0 | .000 | 83.0 | .590 |
| Jack Kochanowicz | StL | sp | 24 | 17 | 0 | .000 | 0 | 7 | .412 | 46 | 2.7 | 11 | 6 | .545 | 90.6 | .610 |
| Jared Koenig* | Tam | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 11 | .282 | 18.7 | .595 |
| Stephen Kolek | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 21.9 | .614 |
| Michael Kopech | SF | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.5 | .564 |
| Dean Kremer | Det | sp | 29 | 32 | 0 | .000 | 0 | 10 | .313 | 153 | 4.8 | 18 | 5 | .278 | 80.3 | .606 |
| Ben Kudrna | | sp | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 27.8 | .611 |
| Alex Lange | LAN | mr | 29 | 5 | 0 | .000 | 0 | 0 | .000 | 11 | 2.2 | 33 | 8 | .242 | 24.1 | .555 |
| Sauryn Lao | Sac | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 21.1 | .619 |
| Andry Lara | LAN | sp | 22 | 31 | 0 | .000 | 0 | 7 | .226 | 110 | 3.5 | 22 | 5 | .227 | 88.1 | .608 |
| Jhancarlos Lara | StL | sp | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 | 14.8 | .543 |
| Jake Latz* | NYA | mr | 29 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 0 | 0 | .000 | 93.0 | .591 |
| Eric Lauer* | Tex | sp | 30 | 5 | 0 | .000 | 0 | 1 | .200 | 30 | 6.0 | 7 | 2 | .286 | 44.6 | .641 |
| Max Lazar | Phi | mr | 26 | 1 | 0 | .000 | 0 | 1 | 1.000 | 3 | 3.0 | 12 | 4 | .333 | 24.2 | .626 |
| Kyle Leahy | ChN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 24.6 | .594 |
| Jordan Leasure | Sac | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 23.6 | .534 |
| Jose Leclerc | Pit | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 | 25.3 | .584 |
| Chase Lee | | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 7 | .304 | 20.0 | .622 |
| Dylan Lee* | Det | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 9 | .346 | 18.7 | .640 |
| Jack Leiter | SF | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 21.9 | .604 |
| Mark Jr. Leiter | | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 20.3 | .616 |
| Matthew Liberatore* | Cin | mr | 25 | 13 | 0 | .000 | 0 | 5 | .385 | 59 | 4.5 | 10 | 5 | .500 | 71.7 | .596 |
| Zack Littell | | sp | 29 | 15 | 0 | .000 | 0 | 6 | .400 | 75 | 5.0 | 14 | 5 | .357 | 52.6 | .650 |
| Brendon Little* | LAN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 12 | .414 | 24.6 | .590 |
| Luke Little* | Col | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 4 | .190 | 19.9 | .593 |
| Ben Lively | Col | sp | 33 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 0 | 0 | .000 | 89.0 | .618 |
| Jonathan Loaisiga | Ari | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 | 20.2 | .643 |
| Ryan Lobus | ChA | mr | 24 | 4 | 0 | .000 | 0 | 2 | .500 | 17 | 4.3 | 4 | 2 | .500 | 66.9 | .616 |
| Nick Lodolo* | | sp | 27 | 24 | 1 | .042 | 0 | 9 | .375 | 143 | 6.0 | 18 | 3 | .167 | 81.4 | .614 |
| Jacob Lopez* | Tex | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 22.6 | .580 |
| Pablo Lopez | Tex | sp | 29 | 14 | 1 | .071 | 1 | 8 | .571 | 65 | 4.6 | 6 | 1 | .167 | 100.9 | .629 |
| Brad Lord | Sac | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 22.1 | .624 |
| Michael Lorenzen | | sp | 33 | 20 | 1 | .050 | 0 | 7 | .350 | 91 | 4.6 | 17 | 6 | .353 | 84.9 | .587 |
| Richard Lovelady* | ChN | mr | 29 | 26 | 0 | .000 | 0 | 11 | .423 | 135 | 5.2 | 14 | 2 | .143 | 83.4 | .648 |
| Seth Lugo | NYN | sp | 35 | 30 | 0 | .000 | 0 | 15 | .500 | 130 | 4.3 | 11 | 4 | .364 | 91.2 | .626 |
| Jesus Luzardo* | Tex | sp | 27 | 10 | 0 | .000 | 0 | 6 | .600 | 52 | 5.2 | 28 | 7 | .250 | 35.7 | .601 |
| Daniel Lynch* | Phi | sp | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 47.0 | .589 |
| Tyler Mahle | Ari | sp | 30 | 11 | 0 | .000 | 0 | 7 | .636 | 47 | 4.3 | 4 | 0 | .000 | 96.0 | .641 |
| Alek Manoah | Sea | sp | 27 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 3 | 0 | .000 | 92.0 | .583 |
| Joe Mantiply* | Col | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 15.7 | .655 |
| Ron Marinaccio | ChA | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 12 | .364 | 22.3 | .564 |
| German Marquez | | sp | 30 | 16 | 0 | .000 | 0 | 7 | .438 | 68 | 4.3 | 9 | 3 | .333 | 74.4 | .604 |
| Yunior Marte | StL | sp | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 | 15.7 | .588 |
| Chris Martin | ChN | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 19.1 | .675 |
| Davis Martin | SD | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 17.0 | .608 |
| Riley Martin* | NYA | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 31.7 | .579 |
| Justin Martinez | Tex | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 20.8 | .574 |
| Nick Martinez | Mil | mr | 34 | 32 | 1 | .031 | 0 | 16 | .500 | 128 | 4.0 | 19 | 7 | .368 | 88.7 | .643 |
| Quinn Mathews* | StL | sp | 24 | 25 | 0 | .000 | 0 | 7 | .280 | 88 | 3.5 | 14 | 7 | .500 | 84.9 | .607 |
| Phil Maton | NYN | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 20.1 | .635 |
| Yuki Matsui* | NYN | mr | 29 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 18 | 4 | .222 | 20.3 | .560 |
| Zebby Matthews | Was | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 13.8 | .689 |
| Isaac Mattson | Ari | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.1 | .542 |
| Steven Matz* | LAA | sp | 34 | 23 | 0 | .000 | 0 | 14 | .609 | 113 | 4.9 | 24 | 4 | .167 | 64.8 | .608 |
| Zach Maxwell | | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 11 | .440 | 23.9 | .571 |
| Dustin May | Was | sp | 27 | 32 | 2 | .063 | 1 | 20 | .625 | 130 | 4.1 | 20 | 2 | .100 | 98.0 | .606 |
| Adam Mazur | Tam | sp | 24 | 4 | 0 | .000 | 0 | 3 | .750 | 26 | 6.5 | 12 | 7 | .583 | 37.5 | .635 |
| Lance McCullers | Tex | sp | 31 | 14 | 0 | .000 | 0 | 6 | .429 | 82 | 5.9 | 13 | 8 | .615 | 93.9 | .588 |
| Chayce McDermott | LAN | sp | 26 | 32 | 0 | .000 | 0 | 12 | .375 | 127 | 4.0 | 22 | 12 | .545 | 95.0 | .588 |
| Griff McGarry | Bal | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 2 | .111 | 22.0 | .526 |
| Easton McGee | | sp | 27 | 4 | 0 | .000 | 0 | 2 | .500 | 23 | 5.8 | 4 | 0 | .000 | 66.2 | .655 |
| Michael McGreevy | ChA | sp | 24 | 32 | 0 | .000 | 0 | 12 | .375 | 129 | 4.0 | 24 | 10 | .417 | 90.3 | .620 |
| Nolan McLean | Atl | dh | 23 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 5 | 0 | .000 | 82.5 | .582 |
| Nick Mears | Phi | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 | 20.4 | .571 |
| Trevor Megill | | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 19.4 | .619 |
| Tylor Megill | NYN | sp | 29 | 6 | 0 | .000 | 0 | 2 | .333 | 22 | 3.7 | 9 | 2 | .222 | 73.4 | .603 |
| Cristian Mena | SD | sp | 22 | 14 | 0 | .000 | 0 | 4 | .286 | 51 | 3.6 | 10 | 5 | .500 | 95.4 | .581 |
| Julian Merryweather | | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 | 20.0 | .591 |
| Luis Mey | Phi | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 30.5 | .541 |
| Max Meyer | ChA | sp | 26 | 30 | 0 | .000 | 0 | 11 | .367 | 108 | 3.6 | 16 | 6 | .375 | 80.2 | .592 |
| Miles Mikolas | | sp | 36 | 17 | 0 | .000 | 0 | 4 | .235 | 68 | 4.0 | 14 | 4 | .286 | 88.8 | .640 |
| Bobby Miller | Bal | sp | 26 | 21 | 0 | .000 | 0 | 7 | .333 | 97 | 4.6 | 8 | 4 | .500 | 84.2 | .605 |
| Bryce Miller | | sp | 26 | 17 | 0 | .000 | 0 | 9 | .529 | 59 | 3.5 | 11 | 5 | .455 | 87.4 | .642 |
| Erik Miller* | Tor | mr | 27 | 11 | 0 | .000 | 0 | 3 | .273 | 41 | 3.7 | 16 | 5 | .313 | 56.0 | .573 |
| Jacob Miller | StL | sp | 21 | 4 | 0 | .000 | 0 | 1 | .250 | 14 | 3.5 | 5 | 1 | .200 | 81.4 | .622 |
| Mason Miller | Bos | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 0 | .000 | 21.0 | .622 |
| Shelby Miller | | mr | 34 | 4 | 0 | .000 | 0 | 0 | .000 | 22 | 5.5 | 19 | 2 | .105 | 29.3 | .610 |
| Tyson Miller | Mil | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 7 | .583 | 19.6 | .621 |
| Hoby Milner* | | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 11 | .355 | 14.7 | .643 |
| Camden Minacci | Cin | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 16.8 | .629 |
| A.J. Minter* | Was | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 21.3 | .583 |
| Andrew Misiaszek* | | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 | 26.1 | .589 |
| Jacob Misiorowski | Tex | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 6 | 2 | .333 | 22.1 | .543 |
| Casey Mize | KC | sp | 28 | 15 | 0 | .000 | 0 | 4 | .267 | 73 | 4.9 | 13 | 2 | .154 | 76.6 | .594 |
| Carmen Mlodzinski | KC | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 47 | 16 | .340 | 17.4 | .617 |
| Keider Montero | | sp | 24 | 5 | 0 | .000 | 0 | 0 | .000 | 20 | 4.0 | 14 | 8 | .571 | 32.6 | .607 |
| Mason Montgomery* | | sp | 25 | 9 | 0 | .000 | 0 | 0 | .000 | 53 | 5.9 | 16 | 2 | .125 | 31.6 | .591 |
| Michael Morales | StL | sp | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 12.5 | .580 |
| Adrian Morejon* | Cle | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 12 | .308 | 17.9 | .612 |
| Dauri Moreta | Mil | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 0 | .000 | 19.3 | .609 |
| David Morgan | Col | mr | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 3 | 2 | .667 | 56.0 | .625 |
| Eli Morgan | Det | mr | 29 | 5 | 0 | .000 | 0 | 1 | .200 | 17 | 3.4 | 4 | 2 | .500 | 92.4 | .621 |
| Andrew Morris | Cin | sp | 23 | 5 | 0 | .000 | 0 | 2 | .400 | 35 | 7.0 | 2 | 2 | 1.000 | 80.7 | .653 |
| Charlie Morton | | sp | 41 | 33 | 0 | .000 | 0 | 14 | .424 | 140 | 4.2 | 16 | 8 | .500 | 91.5 | .597 |
| Andres Munoz | Sea | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 7 | .280 | 20.3 | .624 |
| Penn Murfee | Pit | mr | 31 | 4 | 0 | .000 | 0 | 1 | .250 | 32 | 8.0 | 4 | 1 | .250 | 34.5 | .618 |
| Tobias Myers | Min | sp | 26 | 23 | 0 | .000 | 0 | 10 | .435 | 113 | 4.9 | 9 | 0 | .000 | 89.8 | .638 |
| Jack Neely | Hou | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 24.6 | .617 |
| Kyle Nelson* | Atl | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 13.9 | .628 |
| Ryne Nelson | Cin | sp | 27 | 30 | 0 | .000 | 0 | 14 | .467 | 122 | 4.1 | 26 | 11 | .423 | 84.9 | .624 |
| Kyle Nicolas | Atl | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 13 | .351 | 24.2 | .587 |
| Doug Nikhazy* | Was | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 21.3 | .588 |
| Aaron Nola | Min | sp | 32 | 15 | 2 | .133 | 2 | 11 | .733 | 78 | 5.2 | 5 | 1 | .200 | 98.8 | .668 |
| Dedniel Nunez | Tex | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 9 | .450 | 22.7 | .600 |
| Juan Nunez | Phi | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 27.0 | .667 |
| Riley O'Brien | ChA | mr | 30 | 2 | 0 | .000 | 0 | 1 | .500 | 5 | 2.5 | 21 | 5 | .238 | 22.9 | .582 |
| Bailey Ober | Phi | sp | 29 | 29 | 1 | .034 | 1 | 15 | .517 | 139 | 4.8 | 15 | 3 | .200 | 91.0 | .643 |
| Shohei Ohtani | Tex | dh | 30 | 16 | 1 | .063 | 0 | 8 | .500 | 101 | 6.3 | 6 | 1 | .167 | 100.4 | .609 |
| Steven Okert* | Bos | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 3 | .158 | 17.2 | .612 |
| Reese Olson | KC | sp | 25 | 19 | 0 | .000 | 0 | 5 | .263 | 101 | 5.3 | 11 | 7 | .636 | 81.7 | .615 |
| Oliver Ortega | Bal | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 10 | .294 | 25.1 | .598 |
| Luis L. Ortiz | SD | sp | 26 | 17 | 0 | .000 | 0 | 6 | .353 | 77 | 4.5 | 11 | 4 | .364 | 85.6 | .607 |
| Eric Orze | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 25.9 | .629 |
| Johan Oviedo | Cle | sp | 27 | 5 | 0 | .000 | 0 | 2 | .400 | 29 | 5.8 | 6 | 3 | .500 | 49.8 | .609 |
| Chris Paddack | LAA | sp | 29 | 32 | 1 | .031 | 0 | 18 | .563 | 148 | 4.6 | 16 | 5 | .313 | 84.8 | .638 |
| Emilio Pagan | ChA | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 10 | .333 | 16.4 | .637 |
| Andrew Painter | Atl | sp | 22 | 9 | 0 | .000 | 0 | 4 | .444 | 29 | 3.2 | 4 | 1 | .250 | 90.7 | .612 |
| Daniel Palencia | Sea | mr | 25 | 13 | 0 | .000 | 0 | 5 | .385 | 56 | 4.3 | 22 | 6 | .273 | 47.0 | .588 |
| Andre Pallante | Min | sp | 26 | 15 | 0 | .000 | 0 | 6 | .400 | 66 | 4.4 | 13 | 8 | .615 | 58.9 | .604 |
| Peyton Pallette | SD | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 21.5 | .686 |
| Mitchell Parker* | Atl | sp | 25 | 15 | 0 | .000 | 0 | 6 | .400 | 69 | 4.6 | 21 | 9 | .429 | 39.2 | .619 |
| Joel Payamps | | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 | 18.4 | .628 |
| Nate Pearson | Hou | mr | 28 | 6 | 0 | .000 | 0 | 0 | .000 | 30 | 5.0 | 9 | 4 | .444 | 51.5 | .607 |
| Ethan Pecko | Hou | sp | 22 | 5 | 0 | .000 | 0 | 2 | .400 | 22 | 4.4 | 15 | 4 | .267 | 35.3 | .608 |
| Elvis Peguero | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 46 | 10 | .217 | 19.7 | .600 |
| Walter Pennington* | NYA | mr | 27 | 2 | 0 | .000 | 0 | 1 | .500 | 11 | 5.5 | 3 | 0 | .000 | 43.0 | .600 |
| Ryan Pepiot | KC | sp | 27 | 31 | 0 | .000 | 0 | 8 | .258 | 139 | 4.5 | 30 | 13 | .433 | 84.9 | .612 |
| Freddy Peralta | Mia | sp | 29 | 36 | 0 | .000 | 0 | 11 | .306 | 196 | 5.4 | 28 | 6 | .214 | 86.6 | .598 |
| Wandy Peralta* | SD | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 1 | .077 | 14.0 | .580 |
| Angel Perdomo* | Mia | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 19.1 | .594 |
| Cionel Perez* | | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 7 | .467 | 17.9 | .596 |
| Eury Perez | Bal | sp | 22 | 19 | 0 | .000 | 0 | 9 | .474 | 95 | 5.0 | 11 | 1 | .091 | 92.5 | .609 |
| Martin Perez* | LAN | sp | 34 | 4 | 0 | .000 | 0 | 3 | .750 | 16 | 4.0 | 3 | 0 | .000 | 90.5 | .635 |
| Jack Perkins | ChA | sp | 25 | 5 | 0 | .000 | 0 | 1 | .200 | 14 | 2.8 | 7 | 3 | .429 | 36.9 | .605 |
| David Peterson* | Sac | sp | 29 | 17 | 0 | .000 | 0 | 11 | .647 | 92 | 5.4 | 31 | 15 | .484 | 48.1 | .622 |
| Chase Petty | ChA | sp | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 35.7 | .604 |
| Brandon Pfaadt | Col | sp | 26 | 31 | 0 | .000 | 0 | 16 | .516 | 181 | 5.8 | 20 | 6 | .300 | 92.1 | .635 |
| Evan Phillips | Mil | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 18.9 | .606 |
| Tyler Phillips | Cle | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 14.0 | .607 |
| Nick Pivetta | Cle | sp | 32 | 20 | 0 | .000 | 0 | 7 | .350 | 102 | 5.1 | 13 | 5 | .385 | 59.0 | .621 |
| Drew Pomeranz* | Was | mr | 36 | 3 | 0 | .000 | 0 | 0 | .000 | 13 | 4.3 | 20 | 3 | .150 | 20.1 | .593 |
| Cody Poteet | NYN | sp | 30 | 8 | 0 | .000 | 0 | 5 | .625 | 46 | 5.8 | 2 | 0 | .000 | 82.9 | .641 |
| Cade Povich* | Bos | sp | 25 | 11 | 0 | .000 | 0 | 3 | .273 | 45 | 4.1 | 6 | 2 | .333 | 87.8 | .623 |
| Ryan Pressly | | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 16.3 | .649 |
| Quinn Priester | Ari | sp | 24 | 20 | 0 | .000 | 0 | 11 | .550 | 101 | 5.1 | 19 | 7 | .368 | 60.3 | .621 |
| A.J. Puk* | LAN | mr | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 1 | 0 | .000 | 28.2 | .603 |
| Jose Quijada* | | mr | 29 | 2 | 0 | .000 | 0 | 0 | .000 | 6 | 3.0 | 15 | 9 | .600 | 22.9 | .583 |
| Jose Quintana* | Pit | sp | 36 | 16 | 0 | .000 | 0 | 5 | .313 | 92 | 5.8 | 14 | 10 | .714 | 85.9 | .608 |
| Cole Ragans* | Was | sp | 27 | 17 | 0 | .000 | 0 | 11 | .647 | 55 | 3.2 | 15 | 5 | .333 | 94.9 | .623 |
| Brooks Raley* | Mia | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 13.4 | .593 |
| Drew Rasmussen | Bos | sp | 29 | 31 | 1 | .032 | 0 | 16 | .516 | 136 | 4.4 | 22 | 7 | .318 | 94.9 | .637 |
| Dylan Ray | StL | sp | 24 | 26 | 0 | .000 | 0 | 6 | .231 | 59 | 2.3 | 25 | 15 | .600 | 77.7 | .595 |
| Robbie Ray* | Pit | sp | 33 | 30 | 1 | .033 | 0 | 12 | .400 | 159 | 5.3 | 13 | 3 | .231 | 89.0 | .624 |
| Sean Reid-Foley | Atl | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 21.1 | .573 |
| Patrick Reilly | StL | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 6 | 2 | .333 | 23.6 | .572 |
| Eric Reyzelman | | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 21.5 | .619 |
| Trevor Richards | NYN | mr | 32 | 4 | 0 | .000 | 0 | 1 | .250 | 25 | 6.3 | 21 | 8 | .381 | 26.5 | .595 |
| Lyon Richardson | NYA | sp | 25 | 4 | 0 | .000 | 0 | 1 | .250 | 18 | 4.5 | 3 | 0 | .000 | 106.0 | .580 |
| Ethan Roberts | Sac | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 2 | .111 | 23.8 | .649 |
| David Robertson | Mil | mr | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 4 | 1.000 | 18.3 | .617 |
| Tekoah Roby | Sac | sp | 23 | 3 | 0 | .000 | 0 | 0 | .000 | 10 | 3.3 | 2 | 2 | 1.000 | 52.5 | .614 |
| Joe Rock* | Cle | sp | 24 | 2 | 0 | .000 | 0 | 1 | .500 | 6 | 3.0 | 9 | 1 | .111 | 27.3 | .600 |
| Kumar Rocker | SD | sp | 25 | 20 | 0 | .000 | 0 | 6 | .300 | 75 | 3.8 | 14 | 5 | .357 | 82.1 | .639 |
| Carlos Rodon* | | sp | 32 | 33 | 0 | .000 | 0 | 13 | .394 | 164 | 5.0 | 18 | 6 | .333 | 92.5 | .629 |
| Carlos F. Rodriguez | | sp | 23 | 15 | 0 | .000 | 0 | 9 | .600 | 67 | 4.5 | 11 | 0 | .000 | 76.2 | .596 |
| Eduardo Rodriguez* | Min | sp | 32 | 27 | 1 | .037 | 0 | 14 | .519 | 136 | 5.0 | 24 | 11 | .458 | 91.3 | .641 |
| Manuel Rodriguez | Pit | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 | 21.6 | .612 |
| Randy Rodriguez | Hou | mr | 25 | 5 | 0 | .000 | 0 | 3 | .600 | 18 | 3.6 | 34 | 8 | .235 | 27.5 | .597 |
| Wilking Rodriguez | Det | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 21.6 | .603 |
| Yariel Rodriguez | ChN | sp | 28 | 7 | 0 | .000 | 0 | 2 | .286 | 24 | 3.4 | 10 | 2 | .200 | 42.8 | .585 |
| Taylor Rogers* | Ari | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 38 | 7 | .184 | 20.6 | .605 |
| Trevor Rogers* | SF | sp | 27 | 13 | 0 | .000 | 0 | 6 | .462 | 43 | 3.3 | 6 | 2 | .333 | 91.2 | .603 |
| Tyler Rogers | Cle | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 15.0 | .659 |
| Drew Rom* | Bos | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 22.8 | .593 |
| Jordan Romano | | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 1 | .036 | 20.4 | .636 |
| JoJo Romero* | Min | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 6 | .207 | 19.5 | .629 |
| Landen Roupp | | mr | 26 | 19 | 0 | .000 | 0 | 8 | .421 | 76 | 4.0 | 24 | 5 | .208 | 59.3 | .572 |
| Joe Ryan | Min | sp | 29 | 33 | 1 | .030 | 1 | 14 | .424 | 174 | 5.3 | 15 | 5 | .333 | 87.7 | .634 |
| Andrew Saalfrank* | Mia | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 26.4 | .578 |
| Erik Sabrowski* | Pit | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 23.1 | .606 |
| Chris Sale* | LAA | sp | 36 | 21 | 0 | .000 | 0 | 14 | .667 | 105 | 5.0 | 5 | 1 | .200 | 94.8 | .653 |
| Cristopher Sanchez* | Tam | sp | 28 | 32 | 0 | .000 | 0 | 15 | .469 | 135 | 4.2 | 18 | 5 | .278 | 86.4 | .617 |
| Nick Sandlin | Col | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 17.7 | .653 |
| Cole Sands | | mr | 27 | 5 | 0 | .000 | 0 | 2 | .400 | 20 | 4.0 | 18 | 2 | .111 | 30.6 | .615 |
| Dennis Santana | Bal | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 19.0 | .601 |
| Tony Santillan | Col | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 | 18.9 | .623 |
| Gregory Santos | LAA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 19.8 | .613 |
| Roki Sasaki | Col | sp | 23 | 10 | 0 | .000 | 0 | 4 | .400 | 52 | 5.2 | 3 | 1 | .333 | 88.4 | .621 |
| Tayler Saucedo* | Mil | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 15.6 | .573 |
| Max Scherzer | Cle | sp | 40 | 17 | 0 | .000 | 0 | 6 | .353 | 80 | 4.7 | 13 | 2 | .154 | 92.4 | .641 |
| Cam Schlittler | | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 8 | .571 | 18.1 | .590 |
| Clarke Schmidt | | sp | 29 | 16 | 0 | .000 | 0 | 7 | .438 | 89 | 5.6 | 14 | 4 | .286 | 91.1 | .597 |
| John Schreiber | | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 18.2 | .610 |
| Noah Schultz* | ChA | sp | 21 | 18 | 0 | .000 | 0 | 3 | .167 | 71 | 3.9 | 9 | 3 | .333 | 80.9 | .612 |
| Spencer Schwellenbach | Atl | sp | 25 | 18 | 0 | .000 | 0 | 9 | .500 | 73 | 4.1 | 9 | 4 | .444 | 95.0 | .634 |
| Christian Scott | NYA | sp | 26 | 6 | 0 | .000 | 0 | 2 | .333 | 9 | 1.5 | 2 | 0 | .000 | 103.0 | .595 |
| Tanner Scott* | NYN | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 | 21.4 | .622 |
| Tayler Scott | Phi | mr | 33 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 11 | 4 | .364 | 20.7 | .633 |
| JP Sears* | Cin | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.0 | .727 |
| Kodai Senga | | sp | 32 | 23 | 0 | .000 | 0 | 13 | .565 | 98 | 4.3 | 16 | 3 | .188 | 87.9 | .593 |
| Luis Severino | Tex | sp | 31 | 12 | 0 | .000 | 0 | 4 | .333 | 79 | 6.6 | 11 | 4 | .364 | 55.8 | .611 |
| Paul Sewald | Cle | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 18.3 | .655 |
| Carson Seymour | | sp | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 9 | 4.5 | 11 | 4 | .364 | 20.8 | .610 |
| Emmet Sheehan | Ari | sp | 25 | 16 | 0 | .000 | 0 | 7 | .438 | 58 | 3.6 | 6 | 1 | .167 | 92.1 | .609 |
| Brady Singer | LAN | sp | 28 | 33 | 2 | .061 | 1 | 19 | .576 | 151 | 4.6 | 19 | 5 | .263 | 103.7 | .628 |
| Paul Skenes | SF | sp | 23 | 28 | 0 | .000 | 0 | 5 | .179 | 113 | 4.0 | 19 | 4 | .211 | 64.3 | .632 |
| Tarik Skubal* | Tam | sp | 28 | 32 | 1 | .031 | 1 | 24 | .750 | 149 | 4.7 | 10 | 2 | .200 | 99.1 | .661 |
| Justin Slaten | Det | mr | 27 | 3 | 0 | .000 | 0 | 0 | .000 | 17 | 5.7 | 14 | 2 | .143 | 22.4 | .639 |
| Ethan Small* | NYN | mr | 28 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 0 | 0 | .000 | 77.0 | .584 |
| Cade Smith | LAA | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 3 | .125 | 19.9 | .622 |
| Shane Smith | SD | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 22.4 | .633 |
| AJ Smith-Shawver | Tex | sp | 22 | 6 | 0 | .000 | 0 | 1 | .167 | 28 | 4.7 | 8 | 1 | .125 | 68.9 | .619 |
| Blake Snell* | | sp | 32 | 14 | 0 | .000 | 0 | 4 | .286 | 63 | 4.5 | 11 | 2 | .182 | 94.6 | .598 |
| Robby Snelling* | Bal | sp | 21 | 19 | 0 | .000 | 0 | 3 | .158 | 106 | 5.6 | 14 | 2 | .143 | 66.1 | .593 |
| Anthony Solometo* | StL | sp | 22 | 3 | 0 | .000 | 0 | 1 | .333 | 8 | 2.7 | 4 | 4 | 1.000 | 39.3 | .607 |
| Jose Soriano | Cin | mr | 26 | 31 | 0 | .000 | 0 | 10 | .323 | 136 | 4.4 | 17 | 3 | .176 | 94.0 | .593 |
| Mike Soroka | Ari | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 | 21.2 | .589 |
| Gregory Soto* | Tam | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 18.7 | .615 |
| Bennett Sousa* | | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 18.4 | .622 |
| Gabe Speier* | Was | mr | 30 | 12 | 0 | .000 | 0 | 7 | .583 | 62 | 5.2 | 14 | 5 | .357 | 47.8 | .622 |
| Mitch Spence | SF | sp | 27 | 12 | 0 | .000 | 0 | 6 | .500 | 49 | 4.1 | 13 | 6 | .462 | 62.3 | .633 |
| Jeffrey Springs* | Bos | sp | 32 | 32 | 0 | .000 | 0 | 13 | .406 | 128 | 4.0 | 21 | 8 | .381 | 84.7 | .633 |
| Brandon Sproat | NYN | sp | 24 | 32 | 0 | .000 | 0 | 11 | .344 | 132 | 4.1 | 21 | 4 | .190 | 83.8 | .607 |
| Ryne Stanek | | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 4 | .211 | 17.2 | .594 |
| Justin Steele* | Tex | sp | 29 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 2 | 0 | .000 | 98.0 | .602 |
| Trevor Stephan | Pit | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 25.0 | .620 |
| Robert Stephenson | | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 17.0 | .640 |
| Brock Stewart | Tex | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 19.2 | .629 |
| Matt Strahm* | | mr | 33 | 14 | 0 | .000 | 0 | 9 | .643 | 72 | 5.1 | 11 | 2 | .182 | 40.3 | .669 |
| Hunter Stratton | Mia | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 3 | .188 | 21.6 | .590 |
| Spencer Strider | Sea | sp | 26 | 23 | 0 | .000 | 0 | 13 | .565 | 119 | 5.2 | 14 | 4 | .286 | 96.6 | .635 |
| Marcus Stroman | Pit | sp | 34 | 7 | 0 | .000 | 0 | 3 | .429 | 35 | 5.0 | 4 | 2 | .500 | 91.9 | .596 |
| Tyler Stuart | SD | sp | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 17 | 5.7 | 1 | 0 | .000 | 83.7 | .606 |
| Jose Suarez* | LAA | sp | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 | 20.3 | .616 |
| Ranger Suarez* | ChN | sp | 29 | 27 | 0 | .000 | 0 | 19 | .704 | 136 | 5.0 | 14 | 2 | .143 | 97.7 | .643 |
| Robert Suarez | Tam | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 34 | 7 | .206 | 18.1 | .626 |
| Tomoyuki Sugano | ChN | sp | 35 | 1 | 0 | .000 | 0 | 1 | 1.000 | 10 | 10.0 | 0 | 0 | .000 | 109.0 | .615 |
| Brent Suter* | LAN | mr | 35 | 5 | 0 | .000 | 0 | 2 | .400 | 17 | 3.4 | 25 | 7 | .280 | 28.6 | .640 |
| Erik Swanson | Tor | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 24.8 | .624 |
| Jameson Taillon | Tam | sp | 33 | 22 | 0 | .000 | 0 | 11 | .500 | 95 | 4.3 | 11 | 2 | .182 | 89.6 | .643 |
| Dillon Tate | Tex | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 16.1 | .616 |
| Troy Taylor | SF | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 7 | .318 | 27.0 | .588 |
| Kai-Wei Teng | Hou | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 | 20.9 | .572 |
| Emiliano Teodo | Tex | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.5 | .561 |
| Caleb Thielbar* | | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 11 | .297 | 18.4 | .618 |
| Keegan Thompson | Det | mr | 30 | 13 | 0 | .000 | 0 | 5 | .385 | 62 | 4.8 | 4 | 3 | .750 | 91.5 | .595 |
| Ryan Thompson | Bos | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 5 | .217 | 21.1 | .641 |
| Trent Thornton | Mil | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 18.9 | .652 |
| Blade Tidwell | Mil | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 29.2 | .577 |
| Jesus Tinoco | Atl | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 23.4 | .575 |
| Jonah Tong | Bos | sp | 22 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 0 | 0 | .000 | 46.0 | .616 |
| Michael Tonkin | NYA | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 40.5 | .574 |
| Justin Topa | | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 | 21.3 | .611 |
| Blake Treinen | | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 17.4 | .631 |
| Edwin Uceta | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 | 22.8 | .616 |
| Miguel Ullola | StL | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 8 | 8.0 | 47 | 18 | .383 | 18.0 | .568 |
| Abner Uribe | Sea | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 21.2 | .574 |
| Jose Urquidy | Cle | sp | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 35.0 | .714 |
| Framber Valdez* | LAA | sp | 31 | 32 | 4 | .125 | 2 | 22 | .688 | 138 | 4.3 | 18 | 3 | .167 | 107.2 | .612 |
| CJ Van Eyk | LAN | sp | 26 | 28 | 0 | .000 | 0 | 8 | .286 | 119 | 4.3 | 17 | 4 | .235 | 89.0 | .610 |
| Carlos Vargas | Sea | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 21.3 | .635 |
| Louie Varland | Atl | sp | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 22 | 7 | .318 | 19.9 | .636 |
| Mike Vasil | SD | sp | 25 | 5 | 0 | .000 | 0 | 3 | .600 | 22 | 4.4 | 9 | 2 | .222 | 44.2 | .618 |
| Randy Vasquez | NYA | sp | 26 | 20 | 0 | .000 | 0 | 5 | .250 | 81 | 4.1 | 19 | 10 | .526 | 64.5 | .597 |
| Justin Verlander | | sp | 42 | 19 | 1 | .053 | 0 | 11 | .579 | 85 | 4.5 | 4 | 0 | .000 | 96.4 | .628 |
| Alex Vesia* | Atl | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 | 21.4 | .611 |
| Will Vest | Sac | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 9 | .346 | 16.1 | .607 |
| Victor Vodnik | LAA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 21.1 | .589 |
| Michael Wacha | | sp | 33 | 24 | 0 | .000 | 0 | 11 | .458 | 117 | 4.9 | 17 | 4 | .235 | 69.6 | .625 |
| Hurston Waldrep | Atl | sp | 23 | 21 | 0 | .000 | 0 | 0 | .000 | 112 | 5.3 | 16 | 3 | .188 | 78.6 | .577 |
| Josh Walker* | Cin | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 23.1 | .625 |
| Ryan Walker | Phi | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 16.6 | .638 |
| Andrew Walters | Mia | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 35.5 | .563 |
| Will Warren | ChN | sp | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 6 | 3.0 | 0 | 0 | .000 | 97.0 | .624 |
| Ryan Weathers* | Col | sp | 25 | 9 | 0 | .000 | 0 | 2 | .222 | 49 | 5.4 | 4 | 0 | .000 | 77.7 | .619 |
| Luke Weaver | Tam | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 12 | .400 | 22.0 | .604 |
| Jacob Webb | Mil | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 42 | 14 | .333 | 20.2 | .604 |
| Logan Webb | Sac | sp | 28 | 34 | 1 | .029 | 0 | 22 | .647 | 109 | 3.2 | 23 | 11 | .478 | 95.6 | .636 |
| Greg Weissert | Mia | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 | 20.3 | .625 |
| Tyler Wells | NYA | sp | 30 | 5 | 0 | .000 | 0 | 3 | .600 | 21 | 4.2 | 2 | 0 | .000 | 98.2 | .668 |
| Hayden Wesneski | NYA | mr | 27 | 8 | 1 | .125 | 1 | 7 | .875 | 15 | 1.9 | 3 | 0 | .000 | 73.8 | .610 |
| Cameron Weston | Tor | sp | 24 | 14 | 0 | .000 | 0 | 5 | .357 | 62 | 4.4 | 12 | 5 | .417 | 77.1 | .615 |
| Zack Wheeler | Phi | sp | 35 | 26 | 4 | .154 | 0 | 15 | .577 | 117 | 4.5 | 21 | 6 | .286 | 109.9 | .628 |
| Carson Whisenhunt* | KC | sp | 24 | 10 | 0 | .000 | 0 | 2 | .200 | 35 | 3.5 | 3 | 0 | .000 | 79.3 | .615 |
| Forrest Whitley | Cin | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 13.5 | .569 |
| Garrett Whitlock | Sac | mr | 29 | 33 | 1 | .030 | 1 | 13 | .394 | 132 | 4.0 | 15 | 6 | .400 | 93.0 | .646 |
| Jordan Wicks* | | sp | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 0 | 0 | .000 | 55.3 | .566 |
| Nathan Wiles | Bal | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 17.8 | .682 |
| Devin Williams | Min | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 18.6 | .623 |
| Gavin Williams | Ari | sp | 25 | 34 | 0 | .000 | 0 | 8 | .235 | 178 | 5.2 | 13 | 1 | .077 | 84.6 | .610 |
| Allan Winans | SD | sp | 29 | 13 | 0 | .000 | 0 | 6 | .462 | 55 | 4.2 | 14 | 6 | .429 | 69.6 | .623 |
| Josh Winckowski | KC | mr | 27 | 13 | 0 | .000 | 0 | 7 | .538 | 43 | 3.3 | 10 | 5 | .500 | 90.1 | .633 |
| Keaton Winn | SF | sp | 27 | 1 | 0 | .000 | 0 | 1 | 1.000 | 3 | 3.0 | 1 | 0 | .000 | 88.0 | .750 |
| Bryan Woo | Pit | sp | 25 | 32 | 0 | .000 | 0 | 19 | .594 | 141 | 4.4 | 15 | 7 | .467 | 84.5 | .649 |
| Brandon Woodruff | Bos | sp | 32 | 13 | 0 | .000 | 0 | 9 | .692 | 47 | 3.6 | 11 | 2 | .182 | 102.6 | .630 |
| Jaden Woods* | SF | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 7 | .389 | 20.9 | .607 |
| Simeon Woods Richardso | Pit | sp | 24 | 9 | 1 | .111 | 1 | 1 | .111 | 34 | 3.8 | 5 | 3 | .600 | 82.1 | .618 |
| Kyle Wright | Col | sp | 29 | 2 | 1 | .500 | 0 | 1 | .500 | 8 | 4.0 | 0 | 0 | .000 | 115.5 | .645 |
| Justin Wrobleski* | Atl | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 5 | 1 | .200 | 28.4 | .610 |
| Yoshinobu Yamamoto | Col | sp | 26 | 32 | 3 | .094 | 2 | 23 | .719 | 170 | 5.3 | 16 | 5 | .313 | 100.5 | .651 |
| Ryan Yarbrough* | NYA | mr | 33 | 15 | 0 | .000 | 0 | 8 | .533 | 58 | 3.9 | 23 | 9 | .391 | 53.6 | .604 |
| Kirby Yates | Min | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 7 | .333 | 21.2 | .578 |
| Craig Yoho | Bos | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 9 | .300 | 20.6 | .590 |
| Brandon Young | Mia | sp | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 7 | 3.5 | 1 | 0 | .000 | 36.7 | .627 |
| Rob Zastryzny* | | mr | 33 | 9 | 0 | .000 | 0 | 3 | .333 | 53 | 5.9 | 17 | 3 | .176 | 35.1 | .614 |
| Ryan Zeferjahn | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 9 | .391 | 22.4 | .585 |
| Angel Zerpa* | | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 19.6 | .631 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | PCH/G | STR% |
| Andrew Abbott* | Det | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 87.1 | .602 |
| Bryan Abreu | Sea | mr | 28 | 12 | 3 | .250 | 8 | .667 | 19 | 36 | 13 | .361 | 70 | 70 | 23 | 18.5 | .609 |
| Jason Adam | Ari | mr | 33 | 12 | 9 | .750 | 2 | .167 | 16 | 42 | 13 | .310 | 65 | 65 | 29 | 19.0 | .618 |
| Zach Agnos | NYA | mr | 24 | 7 | 3 | .429 | 4 | .571 | 3 | 46 | 16 | .348 | 53 | 53 | 20 | 26.2 | .606 |
| Keegan Akin* | Phi | mr | 30 | 12 | 7 | .583 | 5 | .417 | 23 | 23 | 4 | .174 | 70 | 70 | 18 | 17.4 | .649 |
| Jorge Alcala | | mr | 29 | 0 | 0 | .000 | 0 | .000 | 11 | 16 | 5 | .313 | 39 | 39 | 9 | 22.1 | .602 |
| Sandy Alcantara | Pit | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 106.7 | .640 |
| Sam Aldegheri* | Atl | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 86.3 | .574 |
| Franco Aleman | KC | mr | 25 | 5 | 2 | .400 | 2 | .400 | 5 | 25 | 7 | .280 | 39 | 39 | 12 | 19.0 | .594 |
| Scott Alexander* | NYN | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 2 | 23 | 4 | .174 | 28 | 25 | 4 | 22.5 | .640 |
| Tyler Alexander* | ChA | mr | 30 | 2 | 1 | .500 | 1 | .500 | 0 | 8 | 3 | .375 | 14 | 11 | 8 | 48.4 | .654 |
| Logan Allen* | Was | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 93.9 | .621 |
| Elvis Alvarado | Tex | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 3 | 6 | 1 | .167 | 8 | 8 | 3 | 20.6 | .606 |
| Jose Alvarado* | Ari | mr | 30 | 9 | 7 | .778 | 2 | .222 | 7 | 5 | 4 | .800 | 28 | 28 | 11 | 21.5 | .615 |
| Kyle Amendt | Atl | mr | 25 | 3 | 1 | .333 | 2 | .667 | 4 | 20 | 5 | .250 | 32 | 32 | 9 | 21.7 | .592 |
| Ian Anderson | NYA | sp | 27 | 2 | 1 | .500 | 1 | .500 | 1 | 6 | 3 | .500 | 23 | 13 | 7 | 51.2 | .609 |
| Tyler Anderson* | Tor | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 96.9 | .630 |
| Shawn Armstrong | Ari | mr | 34 | 4 | 4 | 1.000 | 0 | .000 | 3 | 12 | 3 | .250 | 24 | 24 | 7 | 18.3 | .626 |
| Spencer Arrighetti | Phi | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 87.5 | .603 |
| Aaron Ashby* | Sea | mr | 27 | 4 | 1 | .250 | 3 | .750 | 0 | 7 | 5 | .714 | 19 | 10 | 6 | 58.0 | .556 |
| Braxton Ashcraft | Atl | sp | 25 | 0 | 0 | .000 | 0 | .000 | 6 | 4 | 0 | .000 | 36 | 12 | 2 | 61.2 | .641 |
| Graham Ashcraft | Was | sp | 27 | 2 | 0 | .000 | 1 | .500 | 2 | 29 | 5 | .172 | 39 | 38 | 12 | 20.5 | .626 |
| Sam Bachman | Tor | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 3 | 22 | 7 | .318 | 32 | 31 | 10 | 21.4 | .588 |
| Henry Baez | Tor | sp | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 12 | 2 | 0 | 76.1 | .621 |
| Bryan Baker | Col | mr | 30 | 2 | 0 | .000 | 2 | 1.000 | 5 | 15 | 3 | .200 | 31 | 31 | 9 | 21.2 | .599 |
| Tanner Banks* | SD | mr | 33 | 14 | 7 | .500 | 7 | .500 | 16 | 40 | 9 | .225 | 72 | 72 | 25 | 19.0 | .629 |
| Scott Barlow | ChN | mr | 32 | 18 | 14 | .778 | 3 | .167 | 12 | 34 | 7 | .206 | 71 | 71 | 28 | 20.5 | .578 |
| Mason Barnett | StL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 36 | 4 | 1 | 85.3 | .602 |
| Chris Bassitt | Mil | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 94.6 | .589 |
| Brady Basso* | Min | sp | 27 | 4 | 1 | .250 | 2 | .500 | 11 | 37 | 14 | .378 | 47 | 47 | 17 | 17.1 | .659 |
| Felix Bautista | ChN | cl | 30 | 20 | 15 | .750 | 5 | .250 | 2 | 14 | 3 | .214 | 40 | 40 | 31 | 20.5 | .611 |
| Shane Baz | Bal | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 39 | 2 | 1 | 81.3 | .600 |
| Eduard Bazardo | Pit | mr | 29 | 3 | 1 | .333 | 2 | .667 | 12 | 45 | 18 | .400 | 57 | 57 | 11 | 20.1 | .631 |
| Tristan Beck | SF | mr | 29 | 9 | 7 | .778 | 2 | .222 | 5 | 42 | 15 | .357 | 46 | 41 | 23 | 38.9 | .626 |
| Ian Bedell | ChA | sp | 25 | 5 | 2 | .400 | 3 | .600 | 4 | 27 | 11 | .407 | 35 | 35 | 10 | 19.3 | .611 |
| David Bednar | LAA | cl | 30 | 6 | 3 | .500 | 2 | .333 | 13 | 55 | 7 | .127 | 63 | 63 | 25 | 16.5 | .635 |
| Jalen Beeks* | LAN | mr | 31 | 5 | 2 | .400 | 3 | .600 | 11 | 64 | 20 | .313 | 79 | 77 | 15 | 27.4 | .596 |
| Clayton Beeter | Col | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 22 | 2 | 0 | 80.2 | .587 |
| Nigel Belgrave | | mr | 23 | 2 | 1 | .500 | 0 | .000 | 10 | 26 | 6 | .231 | 35 | 35 | 10 | 20.9 | .559 |
| Brayan Bello | Mil | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 91.6 | .620 |
| Valente Bellozo | Tor | sp | 25 | 2 | 1 | .500 | 1 | .500 | 4 | 29 | 10 | .345 | 40 | 38 | 10 | 25.2 | .628 |
| Anthony Bender | Mil | mr | 30 | 8 | 7 | .875 | 1 | .125 | 7 | 21 | 5 | .238 | 38 | 38 | 18 | 17.8 | .601 |
| Ryan Bergert | Hou | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 14 | 5 | .357 | 21 | 21 | 3 | 27.3 | .614 |
| Brennan Bernardino* | | mr | 33 | 4 | 3 | .750 | 1 | .250 | 10 | 19 | 4 | .211 | 50 | 48 | 15 | 19.4 | .611 |
| Jose Berrios | | sp | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 1 | .111 | 37 | 13 | 4 | 72.3 | .635 |
| Prelander Berroa | SF | mr | 25 | 3 | 0 | .000 | 3 | 1.000 | 2 | 17 | 6 | .353 | 28 | 25 | 9 | 39.3 | .573 |
| Tanner Bibee | Was | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 92.5 | .635 |
| Phil Bickford | ChN | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 3 | 4 | 0 | .000 | 35 | 10 | 5 | 62.8 | .638 |
| Osvaldo Bido | | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 1 | 0 | 86.7 | .583 |
| Shane Bieber | Hou | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 96.7 | .621 |
| Hayden Birdsong | Bos | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 5 | 5 | 2 | 29.4 | .565 |
| Ronel Blanco | Col | sp | 31 | 5 | 2 | .400 | 3 | .600 | 3 | 7 | 1 | .143 | 21 | 19 | 6 | 32.5 | .596 |
| A.J. Blubaugh | | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 31 | 8 | 2 | 67.1 | .608 |
| Ryan Borucki* | LAN | mr | 31 | 2 | 1 | .500 | 1 | .500 | 3 | 47 | 16 | .340 | 47 | 47 | 12 | 24.2 | .573 |
| Matt Boyd* | Tex | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 83.5 | .636 |
| Joe Boyle | NYA | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 4 | .667 | 43 | 15 | 6 | 69.3 | .521 |
| Kyle Bradish | Bal | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 105.7 | .647 |
| Taj Bradley | | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 89.1 | .616 |
| Matt Brash | Col | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 2 | 16 | 3 | .188 | 35 | 20 | 8 | 50.0 | .589 |
| Ryan Brasier | Pit | mr | 37 | 5 | 2 | .400 | 3 | .600 | 12 | 13 | 2 | .154 | 39 | 39 | 10 | 15.2 | .636 |
| Mitch Bratt* | StL | sp | 21 | 6 | 1 | .167 | 5 | .833 | 15 | 54 | 23 | .426 | 103 | 102 | 20 | 16.1 | .624 |
| Lucas Braun | | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 4 | 1 | .250 | 15 | 9 | 7 | 51.1 | .618 |
| Huascar Brazoban | NYN | mr | 35 | 8 | 4 | .500 | 3 | .375 | 8 | 58 | 13 | .224 | 70 | 69 | 30 | 23.3 | .582 |
| John Brebbia | ChA | mr | 35 | 7 | 4 | .571 | 3 | .429 | 9 | 37 | 14 | .378 | 57 | 56 | 14 | 17.0 | .599 |
| Jhony Brito | ChA | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 93.1 | .645 |
| Ben Brown | Sea | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 86.1 | .598 |
| Hunter Brown | Mia | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 0 | 0 | 91.1 | .618 |
| Kris Bubic* | Tex | mr | 27 | 3 | 1 | .333 | 1 | .333 | 4 | 13 | 2 | .154 | 27 | 15 | 3 | 48.4 | .630 |
| Walker Buehler | Phi | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 88.2 | .636 |
| J.B. Bukauskas | LAN | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 2 | 17.0 | .735 |
| Aaron Bummer* | | mr | 31 | 23 | 18 | .783 | 5 | .217 | 9 | 44 | 13 | .295 | 68 | 68 | 42 | 17.9 | .632 |
| Brock Burke* | | mr | 28 | 7 | 4 | .571 | 3 | .429 | 12 | 38 | 8 | .211 | 60 | 60 | 24 | 25.4 | .607 |
| Sean Burke | LAA | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 2 | 23 | 6 | .261 | 27 | 27 | 9 | 20.1 | .607 |
| Corbin Burnes | Ari | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 97.3 | .633 |
| Tanner Burns | ChA | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 3 | 9 | 3 | .333 | 44 | 19 | 4 | 62.8 | .572 |
| Ryan Burr | KC | mr | 31 | 0 | 0 | .000 | 0 | .000 | 4 | 6 | 3 | .500 | 9 | 9 | 4 | 15.4 | .669 |
| Mike Burrows | Sea | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 0 | .000 | 7 | 7 | 6 | 17.1 | .642 |
| Jose Butto | | mr | 27 | 15 | 6 | .400 | 8 | .533 | 11 | 26 | 14 | .538 | 52 | 51 | 17 | 22.2 | .575 |
| Edward Cabrera | Atl | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 25 | 1 | 1 | 74.4 | .590 |
| Jean Cabrera | Tor | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 3 | 16 | 8 | .500 | 32 | 29 | 10 | 27.4 | .604 |
| Noah Cameron* | Cin | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 78.1 | .630 |
| Griffin Canning | StL | sp | 29 | 5 | 3 | .600 | 1 | .200 | 2 | 51 | 19 | .373 | 62 | 62 | 16 | 18.0 | .607 |
| Jonathan Cannon | SD | sp | 24 | 3 | 1 | .333 | 1 | .333 | 6 | 8 | 3 | .375 | 16 | 16 | 3 | 22.8 | .633 |
| Yennier Cano | ChN | mr | 31 | 7 | 2 | .286 | 4 | .571 | 15 | 38 | 13 | .342 | 60 | 59 | 16 | 23.5 | .625 |
| Joey Cantillo* | SF | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 25 | 3 | 1 | 80.6 | .585 |
| Ben Casparius | ChA | sp | 26 | 2 | 1 | .500 | 1 | .500 | 1 | 9 | 3 | .333 | 29 | 19 | 9 | 47.2 | .569 |
| Jose Castillo* | ChN | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 7 | 5 | 3 | 44.3 | .574 |
| Luis Castillo | Bos | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 97.3 | .636 |
| Miguel Castro | Min | mr | 30 | 3 | 2 | .667 | 1 | .333 | 4 | 7 | 1 | .143 | 23 | 23 | 7 | 23.3 | .595 |
| Cade Cavalli | Sac | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 83.7 | .595 |
| Dylan Cease | Mil | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 88.8 | .611 |
| Slade Cecconi | SD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 90.4 | .631 |
| Andrew Chafin* | Sac | mr | 35 | 3 | 2 | .667 | 1 | .333 | 14 | 15 | 6 | .400 | 33 | 33 | 6 | 14.5 | .583 |
| Bubba Chandler | SF | sp | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 17 | 5 | 1 | 74.6 | .591 |
| Aroldis Chapman* | LAA | mr | 37 | 10 | 6 | .600 | 3 | .300 | 16 | 34 | 7 | .206 | 60 | 60 | 13 | 21.0 | .577 |
| Jesse Chavez | ChA | mr | 41 | 2 | 0 | .000 | 2 | 1.000 | 3 | 11 | 2 | .182 | 17 | 17 | 4 | 20.4 | .590 |
| Po-Yu Chen | StL | sp | 23 | 3 | 1 | .333 | 2 | .667 | 1 | 14 | 7 | .500 | 23 | 23 | 3 | 17.2 | .629 |
| Jack Choate* | ChN | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 1 | 1 | 1 | 17.0 | .529 |
| Marc Church | Mil | mr | 24 | 3 | 1 | .333 | 2 | .667 | 4 | 12 | 2 | .167 | 27 | 27 | 7 | 22.7 | .595 |
| Aaron Civale | Min | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 78.3 | .587 |
| Emmanuel Clase | Sea | cl | 27 | 18 | 15 | .833 | 3 | .167 | 1 | 8 | 3 | .375 | 40 | 40 | 29 | 19.7 | .645 |
| Garrett Cleavinger* | Ari | mr | 31 | 15 | 6 | .400 | 8 | .533 | 13 | 43 | 15 | .349 | 66 | 66 | 20 | 21.1 | .587 |
| Adisyn Coffey | Hou | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 1 | 13 | 8 | .615 | 19 | 19 | 6 | 21.9 | .591 |
| Roansy Contreras | Det | mr | 25 | 5 | 4 | .800 | 1 | .200 | 2 | 16 | 8 | .500 | 54 | 31 | 17 | 50.9 | .621 |
| Nestor Cortes* | | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 13 | 3 | 3 | 72.0 | .627 |
| Danny Coulombe* | Det | mr | 35 | 3 | 1 | .333 | 2 | .667 | 21 | 44 | 10 | .227 | 70 | 70 | 15 | 17.4 | .632 |
| Austin Cox* | ChA | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 1 | 5 | 1 | .200 | 15 | 12 | 9 | 50.3 | .585 |
| Cooper Criswell | Mil | sp | 28 | 5 | 1 | .200 | 4 | .800 | 1 | 21 | 10 | .476 | 29 | 29 | 16 | 19.2 | .634 |
| Garrett Crochet* | Cle | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 85.2 | .627 |
| Declan Cronin | Tam | mr | 27 | 2 | 2 | 1.000 | 0 | .000 | 2 | 18 | 5 | .278 | 26 | 26 | 11 | 21.5 | .625 |
| Fernando Cruz | Hou | mr | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 89.3 | .593 |
| Yoniel Curet | Sac | sp | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 1 | .111 | 16 | 16 | 4 | 23.8 | .550 |
| Xzavion Curry | SF | sp | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 10 | 1 | .100 | 17 | 9 | 7 | 64.4 | .638 |
| Caden Dana | NYA | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 89.3 | .644 |
| Davis Daniel | Phi | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 90.2 | .621 |
| Hagen Danner | Cin | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 3 | 22 | 6 | .273 | 24 | 24 | 8 | 22.8 | .664 |
| Yu Darvish | | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 87.7 | .635 |
| Duncan Davitt | StL | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 3 | 44 | 19 | .432 | 55 | 49 | 16 | 27.3 | .613 |
| Enyel de los Santos | Mil | mr | 29 | 5 | 2 | .400 | 3 | .600 | 6 | 23 | 9 | .391 | 32 | 32 | 15 | 19.3 | .606 |
| Yerry de los Santos | NYA | mr | 27 | 6 | 4 | .667 | 2 | .333 | 1 | 13 | 2 | .154 | 22 | 22 | 9 | 30.1 | .618 |
| Jacob deGrom | | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 82.3 | .649 |
| Reid Detmers* | | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 0 | .000 | 10 | 6 | 2 | 56.1 | .594 |
| Alexis Diaz | Det | cl | 28 | 6 | 1 | .167 | 4 | .667 | 25 | 26 | 6 | .231 | 65 | 65 | 13 | 22.8 | .576 |
| Edwin Diaz | LAA | cl | 31 | 40 | 33 | .825 | 7 | .175 | 4 | 31 | 6 | .194 | 60 | 60 | 50 | 20.4 | .628 |
| Miguel Diaz | | mr | 30 | 7 | 2 | .286 | 5 | .714 | 12 | 38 | 9 | .237 | 62 | 62 | 14 | 19.4 | .624 |
| Yilber Diaz | Hou | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 2 | .286 | 27 | 4 | 1 | 84.2 | .584 |
| Hunter Dobbins | Sea | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 86.7 | .600 |
| Dylan Dodd* | Sac | sp | 27 | 1 | 0 | .000 | 0 | .000 | 3 | 5 | 2 | .400 | 9 | 9 | 2 | 15.9 | .650 |
| Chase Dollander | Ari | sp | 23 | 2 | 0 | .000 | 2 | 1.000 | 0 | 13 | 2 | .154 | 27 | 21 | 10 | 38.2 | .593 |
| Seranthony Dominguez | Was | mr | 30 | 10 | 6 | .600 | 4 | .400 | 14 | 37 | 15 | .405 | 68 | 68 | 25 | 19.8 | .580 |
| Camilo Doval | Cle | cl | 27 | 31 | 28 | .903 | 3 | .097 | 3 | 30 | 8 | .267 | 56 | 56 | 49 | 16.6 | .606 |
| Jack Dreyer* | KC | mr | 26 | 16 | 4 | .250 | 10 | .625 | 26 | 53 | 16 | .302 | 98 | 98 | 27 | 20.0 | .615 |
| Jhoan Duran | Sea | cl | 27 | 14 | 11 | .786 | 3 | .214 | 12 | 24 | 6 | .250 | 68 | 68 | 26 | 20.8 | .642 |
| Zach Eflin | | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 20 | 2 | 2 | 89.3 | .654 |
| Brandon Eisert* | Det | mr | 27 | 7 | 4 | .571 | 2 | .286 | 5 | 34 | 16 | .471 | 38 | 36 | 12 | 22.6 | .619 |
| Bryce Elder | NYN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 98.1 | .605 |
| Magnus Ellerts | Atl | mr | 24 | 6 | 2 | .333 | 3 | .500 | 14 | 42 | 15 | .357 | 66 | 66 | 16 | 19.0 | .590 |
| Mason Englert | Atl | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 19.0 | .737 |
| Nic Enright | Cin | mr | 28 | 5 | 0 | .000 | 3 | .600 | 12 | 17 | 6 | .353 | 47 | 40 | 10 | 31.1 | .617 |
| Nathan Eovaldi | Sac | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 94.3 | .643 |
| Lucas Erceg | LAN | mr | 30 | 40 | 34 | .850 | 6 | .150 | 4 | 36 | 10 | .278 | 66 | 66 | 56 | 19.5 | .611 |
| Carlos Estevez | | cl | 32 | 6 | 2 | .333 | 4 | .667 | 13 | 29 | 9 | .310 | 63 | 62 | 21 | 20.3 | .628 |
| Jeremiah Estrada | Sea | mr | 26 | 4 | 1 | .250 | 2 | .500 | 18 | 47 | 15 | .319 | 71 | 71 | 8 | 20.1 | .598 |
| Logan Evans | Tor | sp | 24 | 4 | 1 | .250 | 3 | .750 | 3 | 9 | 0 | .000 | 28 | 24 | 15 | 27.5 | .580 |
| Pete Fairbanks | ChN | cl | 31 | 5 | 4 | .800 | 0 | .000 | 9 | 16 | 3 | .188 | 43 | 40 | 13 | 26.1 | .624 |
| Bailey Falter* | KC | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 85.9 | .647 |
| Calvin Faucher | | mr | 29 | 19 | 15 | .789 | 4 | .211 | 6 | 32 | 12 | .375 | 62 | 62 | 35 | 19.2 | .590 |
| Erick Fedde | Tam | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 83.6 | .585 |
| Ryan Feltner | Mil | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 87.7 | .619 |
| Caleb Ferguson* | LAA | mr | 28 | 3 | 1 | .333 | 2 | .667 | 10 | 19 | 3 | .158 | 37 | 32 | 7 | 25.1 | .614 |
| Ryan Fernandez | | mr | 27 | 2 | 1 | .500 | 1 | .500 | 5 | 39 | 18 | .462 | 40 | 40 | 10 | 22.0 | .598 |
| Jose A. Ferrer* | Hou | mr | 25 | 7 | 3 | .429 | 3 | .429 | 22 | 36 | 7 | .194 | 71 | 71 | 19 | 19.4 | .636 |
| David Festa | Hou | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 2 | 6 | 0 | .000 | 23 | 9 | 2 | 56.9 | .601 |
| Kyle Finnegan | NYN | cl | 33 | 4 | 2 | .500 | 2 | .500 | 6 | 30 | 12 | .400 | 37 | 37 | 15 | 25.2 | .606 |
| Braydon Fisher | LAN | mr | 24 | 8 | 5 | .625 | 2 | .250 | 10 | 45 | 12 | .267 | 73 | 68 | 26 | 24.2 | .579 |
| Jack Flaherty | | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 88.6 | .628 |
| Jose Fleury | StL | sp | 23 | 6 | 2 | .333 | 4 | .667 | 5 | 30 | 10 | .333 | 66 | 52 | 23 | 35.7 | .597 |
| Dylan Floro | Was | mr | 34 | 15 | 11 | .733 | 4 | .267 | 12 | 29 | 6 | .207 | 56 | 56 | 20 | 20.2 | .625 |
| Mason Fluharty* | | mr | 23 | 14 | 7 | .500 | 6 | .429 | 3 | 45 | 17 | .378 | 62 | 62 | 26 | 26.2 | .612 |
| Jason Foley | Sac | cl | 29 | 2 | 2 | 1.000 | 0 | .000 | 1 | 4 | 3 | .750 | 8 | 8 | 6 | 15.1 | .595 |
| J.P. France | KC | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 84.3 | .602 |
| Bowden Francis | Tex | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 92.9 | .670 |
| Max Fried* | Ari | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 99.7 | .622 |
| Kody Funderburk* | | mr | 28 | 4 | 0 | .000 | 3 | .750 | 10 | 17 | 4 | .235 | 35 | 35 | 11 | 19.1 | .620 |
| Hunter Gaddis | Bos | mr | 27 | 3 | 2 | .667 | 1 | .333 | 8 | 18 | 5 | .278 | 49 | 31 | 13 | 47.1 | .638 |
| Matt Gage* | NYA | mr | 32 | 1 | 1 | 1.000 | 0 | .000 | 2 | 1 | 1 | 1.000 | 8 | 8 | 3 | 19.1 | .595 |
| Zac Gallen | Mia | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 0 | 0 | 98.8 | .619 |
| Brandyn Garcia* | Bal | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 1 | 1.000 | 1 | 1 | 0 | 10.0 | .500 |
| Luis A. Garcia | | mr | 38 | 8 | 2 | .250 | 5 | .625 | 13 | 34 | 15 | .441 | 60 | 60 | 18 | 18.8 | .642 |
| Robert Garcia* | Was | mr | 29 | 8 | 7 | .875 | 1 | .125 | 13 | 36 | 10 | .278 | 68 | 68 | 22 | 18.0 | .609 |
| Yimi Garcia | Hou | mr | 34 | 5 | 4 | .800 | 1 | .200 | 5 | 14 | 7 | .500 | 22 | 22 | 13 | 16.5 | .617 |
| Reed Garrett | NYN | mr | 32 | 10 | 3 | .300 | 5 | .500 | 18 | 30 | 9 | .300 | 66 | 66 | 18 | 20.9 | .601 |
| Robert Gasser* | Cin | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 84.4 | .604 |
| Kevin Gausman | Min | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 95.9 | .635 |
| Paul Gervase | | mr | 25 | 9 | 4 | .444 | 5 | .556 | 12 | 59 | 26 | .441 | 66 | 66 | 17 | 23.6 | .556 |
| Kyle Gibson | Bos | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 103.8 | .600 |
| Luis Gil | SD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 81.8 | .621 |
| Logan Gilbert | Ari | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 92.9 | .641 |
| Kevin Ginkel | | mr | 31 | 8 | 5 | .625 | 2 | .250 | 7 | 20 | 2 | .100 | 38 | 38 | 15 | 18.8 | .637 |
| J.T. Ginn | | sp | 26 | 1 | 0 | .000 | 1 | 1.000 | 2 | 25 | 10 | .400 | 39 | 35 | 12 | 27.4 | .590 |
| Lucas Giolito | Mia | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 104.3 | .623 |
| Sawyer Gipson-Long | Mia | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 89.3 | .625 |
| Tyler Glasnow | Sea | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 92.1 | .630 |
| Yoendrys Gomez | SD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 1 | .167 | 11 | 11 | 1 | 18.8 | .589 |
| Tony Gonsolin | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 80.0 | .650 |
| Colton Gordon* | | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 4 | .400 | 27 | 8 | 3 | 70.4 | .637 |
| MacKenzie Gore* | | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 85.6 | .611 |
| Gordon Graceffo | Min | sp | 25 | 6 | 4 | .667 | 2 | .333 | 3 | 14 | 2 | .143 | 29 | 29 | 16 | 20.8 | .585 |
| Andre Granillo | NYA | mr | 25 | 7 | 3 | .429 | 4 | .571 | 2 | 34 | 11 | .324 | 47 | 47 | 23 | 25.6 | .561 |
| Kendall Graveman | NYN | mr | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 1 | .500 | 12 | 10 | 3 | 31.2 | .591 |
| Jon Gray | Sac | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 97.8 | .628 |
| Sonny Gray | Phi | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 94.8 | .626 |
| Chad Green | ChN | mr | 34 | 7 | 3 | .429 | 4 | .571 | 9 | 24 | 13 | .542 | 41 | 41 | 15 | 21.9 | .638 |
| Hunter Greene | Col | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 97.5 | .615 |
| Sean Guenther* | Bal | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 | 31.0 | .613 |
| Luis Guerrero | | mr | 24 | 4 | 2 | .500 | 2 | .500 | 4 | 21 | 6 | .286 | 32 | 32 | 17 | 29.8 | .569 |
| Ryan Gusto | | sp | 26 | 1 | 0 | .000 | 1 | 1.000 | 3 | 8 | 4 | .500 | 14 | 13 | 3 | 32.2 | .599 |
| Josh Hader* | | cl | 31 | 21 | 19 | .905 | 2 | .095 | 2 | 21 | 5 | .238 | 40 | 40 | 33 | 18.9 | .601 |
| Skylar Hales | Atl | mr | 23 | 3 | 1 | .333 | 2 | .667 | 4 | 19 | 10 | .526 | 33 | 33 | 12 | 24.5 | .629 |
| DL Hall* | Bal | sp | 26 | 2 | 2 | 1.000 | 0 | .000 | 4 | 17 | 3 | .176 | 27 | 26 | 7 | 22.1 | .584 |
| Seth Halvorsen | Hou | mr | 25 | 17 | 15 | .882 | 2 | .118 | 6 | 26 | 6 | .231 | 49 | 49 | 32 | 19.4 | .604 |
| Ian Hamilton | Tex | mr | 30 | 5 | 2 | .400 | 3 | .600 | 2 | 5 | 0 | .000 | 33 | 13 | 5 | 58.9 | .596 |
| Emerson Hancock | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 91.5 | .577 |
| Brenan Hanifee | Det | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 0 | 0 | 92.4 | .625 |
| Landon Harper | Cin | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 6 | 5 | 4 | 29.0 | .661 |
| Thomas Harrington | Sea | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 81.3 | .618 |
| Hayden Harris* | Cle | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 3 | 3 | 0 | 15.0 | .511 |
| Kyle Harrison* | | sp | 23 | 0 | 0 | .000 | 0 | .000 | 4 | 6 | 2 | .333 | 35 | 8 | 0 | 67.2 | .622 |
| Kyle Hart* | Mil | sp | 32 | 1 | 1 | 1.000 | 0 | .000 | 1 | 6 | 1 | .167 | 34 | 5 | 3 | 79.4 | .645 |
| Grant Hartwig | NYN | mr | 27 | 3 | 3 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 10 | 10 | 4 | 21.4 | .561 |
| Hunter Harvey | Hou | mr | 30 | 5 | 2 | .400 | 3 | .600 | 1 | 12 | 6 | .500 | 14 | 14 | 8 | 24.1 | .618 |
| Brent Headrick* | NYA | sp | 27 | 1 | 1 | 1.000 | 0 | .000 | 2 | 6 | 2 | .333 | 15 | 11 | 4 | 43.5 | .617 |
| Andrew Heaney* | StL | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 2 | .500 | 27 | 4 | 4 | 76.1 | .619 |
| Ryan Helsley | Col | cl | 30 | 23 | 15 | .652 | 8 | .348 | 2 | 39 | 17 | .436 | 56 | 56 | 42 | 21.2 | .601 |
| Logan Henderson | SF | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 2 | 15 | 5 | .333 | 44 | 21 | 15 | 56.8 | .626 |
| Liam Hendriks | ChN | cl | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 4 | 4 | 2 | 21.5 | .593 |
| Edgardo Henriquez | Atl | mr | 23 | 2 | 2 | 1.000 | 0 | .000 | 3 | 19 | 7 | .368 | 25 | 25 | 11 | 22.8 | .567 |
| Ronny Henriquez | Tex | mr | 25 | 4 | 3 | .750 | 1 | .250 | 9 | 24 | 7 | .292 | 51 | 51 | 15 | 18.6 | .583 |
| Cole Henry | Tor | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 2 | 23 | 1 | .043 | 26 | 26 | 4 | 17.9 | .569 |
| Tommy Henry* | LAA | sp | 27 | 1 | 1 | 1.000 | 0 | .000 | 2 | 12 | 7 | .583 | 15 | 15 | 5 | 19.5 | .579 |
| Carlos Hernandez | ChN | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 92.9 | .601 |
| Daysbel Hernandez | | mr | 28 | 10 | 2 | .200 | 7 | .700 | 12 | 21 | 7 | .333 | 44 | 44 | 8 | 21.4 | .573 |
| Tim Herrin* | | mr | 28 | 13 | 7 | .538 | 2 | .154 | 19 | 43 | 13 | .302 | 82 | 82 | 24 | 16.9 | .601 |
| Jordan Hicks | SF | mr | 28 | 17 | 15 | .882 | 2 | .118 | 2 | 16 | 4 | .250 | 40 | 33 | 23 | 40.8 | .554 |
| Jaden Hill | | mr | 25 | 4 | 3 | .750 | 1 | .250 | 1 | 8 | 1 | .125 | 13 | 9 | 7 | 56.9 | .591 |
| Sean Hjelle | SF | mr | 28 | 3 | 1 | .333 | 2 | .667 | 6 | 34 | 12 | .353 | 53 | 49 | 11 | 33.1 | .606 |
| Porter Hodge | Was | mr | 24 | 10 | 8 | .800 | 2 | .200 | 1 | 22 | 3 | .136 | 37 | 37 | 29 | 24.6 | .565 |
| Bryan Hoeing | | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 0 | .000 | 25 | 4 | 2 | 87.1 | .629 |
| Jeff Hoffman | Min | mr | 32 | 13 | 7 | .538 | 6 | .462 | 18 | 31 | 11 | .355 | 64 | 64 | 21 | 21.1 | .619 |
| Andrew Hoffmann | Hou | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 3 | .375 | 20 | 4 | 2 | 68.7 | .596 |
| Gunnar Hoglund | Sac | sp | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 18 | 9 | .500 | 19 | 19 | 9 | 16.6 | .623 |
| Colin Holderman | Bal | mr | 29 | 4 | 1 | .250 | 3 | .750 | 10 | 22 | 5 | .227 | 47 | 40 | 6 | 30.2 | .585 |
| Grant Holman | KC | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 0 | 12 | 1 | .083 | 19 | 19 | 9 | 17.4 | .645 |
| Clay Holmes | Sac | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 84.7 | .623 |
| Grant Holmes | Mia | mr | 29 | 2 | 1 | .500 | 1 | .500 | 19 | 19 | 4 | .211 | 50 | 50 | 9 | 17.4 | .630 |
| Tyler Holton* | Cle | mr | 29 | 5 | 1 | .200 | 3 | .600 | 20 | 31 | 11 | .355 | 61 | 54 | 11 | 24.6 | .646 |
| Cade Horton | Tam | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 1 | 1 | 81.1 | .628 |
| Tanner Houck | LAN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 85.4 | .611 |
| Adrian Houser | StL | sp | 32 | 5 | 2 | .400 | 3 | .600 | 2 | 25 | 9 | .360 | 31 | 31 | 11 | 22.4 | .599 |
| Bryan Hudson* | Col | mr | 28 | 5 | 3 | .600 | 2 | .400 | 10 | 40 | 15 | .375 | 71 | 71 | 16 | 19.2 | .623 |
| Brandon Hughes* | NYN | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 85.8 | .618 |
| K.C. Hunt | Bos | sp | 24 | 0 | 0 | .000 | 0 | .000 | 12 | 20 | 5 | .250 | 47 | 31 | 11 | 42.0 | .604 |
| Brant Hurter* | ChN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 87.0 | .639 |
| Raisel Iglesias | | cl | 35 | 16 | 8 | .500 | 7 | .438 | 17 | 31 | 10 | .323 | 68 | 68 | 23 | 18.5 | .648 |
| Shota Imanaga* | Col | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 91.4 | .646 |
| Jairo Iriarte | Col | sp | 23 | 2 | 1 | .500 | 1 | .500 | 1 | 14 | 4 | .286 | 18 | 16 | 8 | 27.3 | .572 |
| Cole Irvin* | | sp | 31 | 5 | 3 | .600 | 2 | .400 | 0 | 24 | 8 | .333 | 38 | 32 | 17 | 34.0 | .625 |
| Jake Irvin | | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 94.4 | .625 |
| Luke Jackson | Bal | mr | 33 | 5 | 2 | .400 | 2 | .400 | 11 | 37 | 8 | .216 | 58 | 58 | 9 | 24.2 | .595 |
| Alek Jacob | Pit | mr | 27 | 7 | 6 | .857 | 1 | .143 | 10 | 32 | 8 | .250 | 60 | 60 | 28 | 22.0 | .589 |
| Drey Jameson | Was | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 90.6 | .606 |
| Kenley Jansen | Tam | cl | 37 | 6 | 2 | .333 | 3 | .500 | 26 | 54 | 16 | .296 | 75 | 75 | 15 | 16.8 | .601 |
| Cristian Javier | Min | sp | 28 | 1 | 1 | 1.000 | 0 | .000 | 2 | 14 | 5 | .357 | 16 | 16 | 3 | 21.9 | .573 |
| Griffin Jax | Mia | mr | 30 | 27 | 24 | .889 | 3 | .111 | 3 | 30 | 5 | .167 | 64 | 64 | 53 | 17.4 | .634 |
| Jackson Jobe | SF | sp | 22 | 1 | 1 | 1.000 | 0 | .000 | 0 | 4 | 2 | .500 | 16 | 3 | 1 | 80.4 | .637 |
| Pierce Johnson | Mil | mr | 34 | 7 | 3 | .429 | 3 | .429 | 9 | 47 | 15 | .319 | 65 | 65 | 21 | 19.6 | .597 |
| Seth Johnson | StL | sp | 26 | 5 | 4 | .800 | 1 | .200 | 0 | 21 | 5 | .238 | 25 | 25 | 21 | 21.4 | .551 |
| Ben Joyce | Sac | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 5 | 5 | 1 | 24.8 | .573 |
| Jakob Junis | Det | mr | 32 | 3 | 3 | 1.000 | 0 | .000 | 0 | 23 | 5 | .217 | 29 | 29 | 16 | 21.4 | .638 |
| Janson Junk | Tex | sp | 29 | 4 | 3 | .750 | 1 | .250 | 2 | 12 | 2 | .167 | 26 | 26 | 15 | 23.7 | .596 |
| Tommy Kahnle | | mr | 35 | 3 | 0 | .000 | 1 | .333 | 8 | 23 | 8 | .348 | 31 | 31 | 5 | 17.3 | .576 |
| James Karinchak | Min | mr | 29 | 2 | 0 | .000 | 1 | .500 | 2 | 13 | 4 | .308 | 21 | 21 | 7 | 21.6 | .577 |
| Mitch Keller | KC | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 91.3 | .628 |
| Kevin Kelly | | mr | 27 | 16 | 12 | .750 | 4 | .250 | 7 | 22 | 8 | .364 | 47 | 47 | 27 | 19.6 | .642 |
| Merrill Kelly | Det | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 22 | 2 | 2 | 89.3 | .622 |
| Zak Kent | KC | sp | 27 | 9 | 4 | .444 | 4 | .444 | 17 | 59 | 25 | .424 | 70 | 70 | 14 | 17.9 | .643 |
| Orion Kerkering | Bos | mr | 24 | 5 | 2 | .400 | 3 | .600 | 16 | 25 | 4 | .160 | 52 | 52 | 12 | 19.3 | .623 |
| Clayton Kershaw* | LAA | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 79.3 | .641 |
| Yusei Kikuchi* | NYN | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 90.7 | .641 |
| Craig Kimbrel | Cle | cl | 37 | 4 | 2 | .500 | 2 | .500 | 5 | 28 | 8 | .286 | 29 | 29 | 6 | 19.8 | .604 |
| Bryan King* | Tam | mr | 28 | 7 | 4 | .571 | 1 | .143 | 14 | 39 | 7 | .179 | 63 | 63 | 16 | 18.1 | .599 |
| John King* | KC | mr | 30 | 37 | 28 | .757 | 8 | .216 | 5 | 42 | 12 | .286 | 73 | 73 | 54 | 14.9 | .643 |
| Michael King | Tam | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 97.0 | .624 |
| George Kirby | Sea | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 87.0 | .654 |
| Andrew Kittredge | ChN | mr | 35 | 4 | 2 | .500 | 2 | .500 | 16 | 21 | 5 | .238 | 45 | 44 | 12 | 21.0 | .645 |
| George Klassen | Bos | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 83.0 | .590 |
| Jack Kochanowicz | StL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 90.6 | .610 |
| Jared Koenig* | Tam | mr | 31 | 4 | 2 | .500 | 1 | .250 | 14 | 19 | 8 | .421 | 50 | 50 | 15 | 18.7 | .595 |
| Stephen Kolek | | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 6 | 27 | 6 | .222 | 42 | 42 | 12 | 21.9 | .614 |
| Michael Kopech | SF | mr | 29 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 2 | 19.5 | .564 |
| Dean Kremer | Det | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 80.3 | .606 |
| Ben Kudrna | | sp | 22 | 1 | 0 | .000 | 1 | 1.000 | 1 | 3 | 1 | .333 | 6 | 6 | 2 | 27.8 | .611 |
| Alex Lange | LAN | mr | 29 | 5 | 2 | .400 | 3 | .600 | 19 | 25 | 11 | .440 | 63 | 58 | 14 | 24.1 | .555 |
| Sauryn Lao | Sac | mr | 25 | 9 | 5 | .556 | 4 | .444 | 10 | 30 | 12 | .400 | 57 | 57 | 26 | 21.1 | .619 |
| Andry Lara | LAN | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 88.1 | .608 |
| Jhancarlos Lara | StL | sp | 22 | 2 | 0 | .000 | 1 | .500 | 3 | 17 | 4 | .235 | 19 | 19 | 3 | 14.8 | .543 |
| Jake Latz* | NYA | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 93.0 | .591 |
| Eric Lauer* | Tex | sp | 30 | 1 | 1 | 1.000 | 0 | .000 | 3 | 8 | 3 | .375 | 16 | 11 | 2 | 44.6 | .641 |
| Max Lazar | Phi | mr | 26 | 4 | 1 | .250 | 3 | .750 | 6 | 33 | 10 | .303 | 46 | 45 | 10 | 24.2 | .626 |
| Kyle Leahy | ChN | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 1 | 7 | 3 | .429 | 11 | 11 | 4 | 24.6 | .594 |
| Jordan Leasure | Sac | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 5 | 5 | 1 | 23.6 | .534 |
| Jose Leclerc | Pit | mr | 31 | 4 | 2 | .500 | 1 | .250 | 4 | 8 | 3 | .375 | 15 | 15 | 3 | 25.3 | .584 |
| Chase Lee | | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 7 | 26 | 9 | .346 | 46 | 46 | 7 | 20.0 | .622 |
| Dylan Lee* | Det | mr | 30 | 25 | 13 | .520 | 12 | .480 | 5 | 46 | 13 | .283 | 69 | 69 | 44 | 18.7 | .640 |
| Jack Leiter | SF | sp | 25 | 1 | 0 | .000 | 0 | .000 | 1 | 24 | 8 | .333 | 23 | 23 | 3 | 21.9 | .604 |
| Mark Jr. Leiter | | mr | 34 | 13 | 11 | .846 | 2 | .154 | 3 | 18 | 7 | .389 | 36 | 36 | 28 | 20.3 | .616 |
| Matthew Liberatore* | Cin | mr | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 2 | .667 | 17 | 4 | 3 | 71.7 | .596 |
| Zack Littell | | sp | 29 | 1 | 1 | 1.000 | 0 | .000 | 2 | 12 | 4 | .333 | 31 | 16 | 7 | 52.6 | .650 |
| Brendon Little* | LAN | mr | 28 | 11 | 4 | .364 | 7 | .636 | 12 | 23 | 8 | .348 | 58 | 58 | 18 | 24.6 | .590 |
| Luke Little* | Col | mr | 24 | 4 | 1 | .250 | 3 | .750 | 6 | 32 | 8 | .250 | 56 | 56 | 17 | 19.9 | .593 |
| Ben Lively | Col | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 89.0 | .618 |
| Jonathan Loaisiga | Ari | mr | 30 | 6 | 6 | 1.000 | 0 | .000 | 2 | 10 | 1 | .100 | 32 | 32 | 16 | 20.2 | .643 |
| Ryan Lobus | ChA | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 10 | 6 | 5 | 66.9 | .616 |
| Nick Lodolo* | | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 2 | .667 | 29 | 5 | 0 | 81.4 | .614 |
| Jacob Lopez* | Tex | sp | 27 | 1 | 1 | 1.000 | 0 | .000 | 2 | 10 | 1 | .100 | 14 | 14 | 3 | 22.6 | .580 |
| Pablo Lopez | Tex | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 100.9 | .629 |
| Brad Lord | Sac | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 4 | 14 | 5 | .357 | 23 | 23 | 10 | 22.1 | .624 |
| Michael Lorenzen | | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 1 | .200 | 24 | 4 | 2 | 84.9 | .587 |
| Richard Lovelady* | ChN | mr | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 28 | 2 | 0 | 83.4 | .648 |
| Seth Lugo | NYN | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 91.2 | .626 |
| Jesus Luzardo* | Tex | sp | 27 | 4 | 3 | .750 | 0 | .000 | 10 | 27 | 11 | .407 | 46 | 36 | 9 | 35.7 | .601 |
| Daniel Lynch* | Phi | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 3 | 2 | 2 | 47.0 | .589 |
| Tyler Mahle | Ari | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 96.0 | .641 |
| Alek Manoah | Sea | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 92.0 | .583 |
| Joe Mantiply* | Col | mr | 34 | 8 | 4 | .500 | 4 | .500 | 9 | 19 | 3 | .158 | 39 | 39 | 9 | 15.7 | .655 |
| Ron Marinaccio | ChA | mr | 29 | 15 | 12 | .800 | 3 | .200 | 13 | 45 | 12 | .267 | 78 | 78 | 47 | 22.3 | .564 |
| German Marquez | | sp | 30 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 0 | .000 | 21 | 5 | 1 | 74.4 | .604 |
| Yunior Marte | StL | sp | 21 | 2 | 2 | 1.000 | 0 | .000 | 4 | 23 | 6 | .261 | 24 | 24 | 4 | 15.7 | .588 |
| Chris Martin | ChN | mr | 39 | 6 | 6 | 1.000 | 0 | .000 | 13 | 15 | 3 | .200 | 44 | 44 | 19 | 19.1 | .675 |
| Davis Martin | SD | sp | 28 | 1 | 1 | 1.000 | 0 | .000 | 1 | 6 | 2 | .333 | 9 | 9 | 5 | 17.0 | .608 |
| Riley Martin* | NYA | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 4 | .286 | 9 | 9 | 7 | 31.7 | .579 |
| Justin Martinez | Tex | mr | 23 | 7 | 4 | .571 | 3 | .429 | 1 | 13 | 4 | .308 | 21 | 21 | 13 | 20.8 | .574 |
| Nick Martinez | Mil | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 88.7 | .643 |
| Quinn Mathews* | StL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 27 | 2 | 2 | 84.9 | .607 |
| Phil Maton | NYN | mr | 32 | 7 | 3 | .429 | 4 | .571 | 2 | 22 | 9 | .409 | 38 | 38 | 14 | 20.1 | .635 |
| Yuki Matsui* | NYN | mr | 29 | 3 | 1 | .333 | 2 | .667 | 7 | 12 | 7 | .583 | 26 | 25 | 5 | 20.3 | .560 |
| Zebby Matthews | Was | sp | 25 | 7 | 5 | .714 | 2 | .286 | 3 | 29 | 10 | .345 | 29 | 29 | 16 | 13.8 | .689 |
| Isaac Mattson | Ari | mr | 29 | 2 | 1 | .500 | 1 | .500 | 0 | 6 | 2 | .333 | 8 | 8 | 8 | 22.1 | .542 |
| Steven Matz* | LAA | sp | 34 | 2 | 0 | .000 | 2 | 1.000 | 1 | 11 | 4 | .364 | 36 | 13 | 3 | 64.8 | .608 |
| Zach Maxwell | | mr | 24 | 5 | 4 | .800 | 1 | .200 | 5 | 37 | 10 | .270 | 37 | 37 | 12 | 23.9 | .571 |
| Dustin May | Was | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 98.0 | .606 |
| Adam Mazur | Tam | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 1 | .143 | 15 | 11 | 1 | 37.5 | .635 |
| Lance McCullers | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 93.9 | .588 |
| Chayce McDermott | LAN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 95.0 | .588 |
| Griff McGarry | Bal | mr | 26 | 2 | 1 | .500 | 1 | .500 | 6 | 18 | 9 | .500 | 25 | 25 | 6 | 22.0 | .526 |
| Easton McGee | | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 6 | 2 | 1 | 66.2 | .655 |
| Michael McGreevy | ChA | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 33 | 1 | 1 | 90.3 | .620 |
| Nolan McLean | Atl | dh | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 82.5 | .582 |
| Nick Mears | Phi | mr | 28 | 7 | 4 | .571 | 2 | .286 | 13 | 34 | 6 | .176 | 59 | 59 | 18 | 20.4 | .571 |
| Trevor Megill | | cl | 31 | 9 | 6 | .667 | 2 | .222 | 3 | 21 | 7 | .333 | 40 | 40 | 15 | 19.4 | .619 |
| Tylor Megill | NYN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 1 | 0 | 73.4 | .603 |
| Cristian Mena | SD | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 95.4 | .581 |
| Julian Merryweather | | mr | 33 | 8 | 5 | .625 | 3 | .375 | 3 | 39 | 11 | .282 | 39 | 39 | 21 | 20.0 | .591 |
| Luis Mey | Phi | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 2 | 2 | 0 | 30.5 | .541 |
| Max Meyer | ChA | sp | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 1 | 1 | 1.000 | 33 | 3 | 3 | 80.2 | .592 |
| Miles Mikolas | | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 88.8 | .640 |
| Bobby Miller | Bal | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 1 | 0 | 84.2 | .605 |
| Bryce Miller | | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 87.4 | .642 |
| Erik Miller* | Tor | mr | 27 | 4 | 0 | .000 | 4 | 1.000 | 1 | 8 | 5 | .625 | 22 | 11 | 1 | 56.0 | .573 |
| Jacob Miller | StL | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 5 | 1 | 1 | 81.4 | .622 |
| Mason Miller | Bos | cl | 26 | 26 | 23 | .885 | 3 | .115 | 2 | 34 | 5 | .147 | 67 | 67 | 55 | 21.0 | .622 |
| Shelby Miller | | mr | 34 | 3 | 2 | .667 | 1 | .333 | 5 | 16 | 5 | .313 | 30 | 26 | 5 | 29.3 | .610 |
| Tyson Miller | Mil | mr | 29 | 3 | 3 | 1.000 | 0 | .000 | 4 | 20 | 5 | .250 | 31 | 31 | 12 | 19.6 | .621 |
| Hoby Milner* | | mr | 34 | 7 | 4 | .571 | 2 | .286 | 19 | 32 | 5 | .156 | 66 | 66 | 17 | 14.7 | .643 |
| Camden Minacci | Cin | mr | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 11 | 3 | .273 | 9 | 9 | 2 | 16.8 | .629 |
| A.J. Minter* | Was | mr | 31 | 10 | 6 | .600 | 2 | .200 | 5 | 16 | 7 | .438 | 29 | 29 | 9 | 21.3 | .583 |
| Andrew Misiaszek* | | mr | 27 | 3 | 2 | .667 | 1 | .333 | 2 | 8 | 3 | .375 | 17 | 16 | 8 | 26.1 | .589 |
| Jacob Misiorowski | Tex | sp | 23 | 3 | 2 | .667 | 1 | .333 | 2 | 17 | 7 | .412 | 19 | 18 | 9 | 22.1 | .543 |
| Casey Mize | KC | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 76.6 | .594 |
| Carmen Mlodzinski | KC | mr | 26 | 7 | 3 | .429 | 4 | .571 | 15 | 69 | 27 | .391 | 88 | 88 | 15 | 17.4 | .617 |
| Keider Montero | | sp | 24 | 2 | 1 | .500 | 1 | .500 | 4 | 12 | 5 | .417 | 20 | 15 | 3 | 32.6 | .607 |
| Mason Montgomery* | | sp | 25 | 4 | 2 | .500 | 2 | .500 | 6 | 16 | 6 | .375 | 38 | 29 | 6 | 31.6 | .591 |
| Michael Morales | StL | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 0 | .000 | 4 | 4 | 4 | 12.5 | .580 |
| Adrian Morejon* | Cle | mr | 26 | 5 | 2 | .400 | 3 | .600 | 25 | 35 | 13 | .371 | 69 | 69 | 13 | 17.9 | .612 |
| Dauri Moreta | Mil | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 4 | 12 | 6 | .500 | 19 | 19 | 3 | 19.3 | .609 |
| David Morgan | Col | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 2 | 1 | 0 | 56.0 | .625 |
| Eli Morgan | Det | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 92.4 | .621 |
| Andrew Morris | Cin | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 1 | 1 | 80.7 | .653 |
| Charlie Morton | | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 35 | 2 | 2 | 91.5 | .597 |
| Andres Munoz | Sea | cl | 26 | 6 | 0 | .000 | 5 | .833 | 24 | 33 | 7 | .212 | 75 | 75 | 10 | 20.3 | .624 |
| Penn Murfee | Pit | mr | 31 | 2 | 1 | .500 | 1 | .500 | 1 | 15 | 6 | .400 | 16 | 12 | 5 | 34.5 | .618 |
| Tobias Myers | Min | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 89.8 | .638 |
| Jack Neely | Hou | mr | 25 | 6 | 3 | .500 | 3 | .500 | 7 | 30 | 9 | .300 | 42 | 42 | 13 | 24.6 | .617 |
| Kyle Nelson* | Atl | mr | 28 | 3 | 0 | .000 | 2 | .667 | 12 | 27 | 11 | .407 | 42 | 42 | 11 | 13.9 | .628 |
| Ryne Nelson | Cin | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 3 | 1.000 | 34 | 4 | 1 | 84.9 | .624 |
| Kyle Nicolas | Atl | mr | 26 | 6 | 3 | .500 | 3 | .500 | 15 | 53 | 13 | .245 | 76 | 76 | 10 | 24.2 | .587 |
| Doug Nikhazy* | Was | sp | 25 | 2 | 2 | 1.000 | 0 | .000 | 0 | 11 | 1 | .091 | 16 | 16 | 12 | 21.3 | .588 |
| Aaron Nola | Min | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 98.8 | .668 |
| Dedniel Nunez | Tex | mr | 29 | 6 | 0 | .000 | 5 | .833 | 21 | 19 | 5 | .263 | 53 | 53 | 8 | 22.7 | .600 |
| Juan Nunez | Phi | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 1 | 1 | 1 | 27.0 | .667 |
| Riley O'Brien | ChA | mr | 30 | 4 | 2 | .500 | 2 | .500 | 12 | 47 | 16 | .340 | 64 | 62 | 4 | 22.9 | .582 |
| Bailey Ober | Phi | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 91.0 | .643 |
| Shohei Ohtani | Tex | dh | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 100.4 | .609 |
| Steven Okert* | Bos | mr | 33 | 6 | 4 | .667 | 2 | .333 | 6 | 28 | 10 | .357 | 43 | 43 | 14 | 17.2 | .612 |
| Reese Olson | KC | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 81.7 | .615 |
| Oliver Ortega | Bal | mr | 28 | 8 | 3 | .375 | 5 | .625 | 10 | 54 | 17 | .315 | 77 | 77 | 26 | 25.1 | .598 |
| Luis L. Ortiz | SD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 85.6 | .607 |
| Eric Orze | | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 1 | 16 | 6 | .375 | 21 | 21 | 10 | 25.9 | .629 |
| Johan Oviedo | Cle | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 0 | .000 | 11 | 6 | 1 | 49.8 | .609 |
| Chris Paddack | LAA | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 84.8 | .638 |
| Emilio Pagan | ChA | mr | 34 | 9 | 2 | .222 | 6 | .667 | 16 | 39 | 13 | .333 | 76 | 76 | 20 | 16.4 | .637 |
| Andrew Painter | Atl | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 90.7 | .612 |
| Daniel Palencia | Sea | mr | 25 | 3 | 2 | .667 | 1 | .333 | 1 | 21 | 5 | .238 | 38 | 25 | 13 | 47.0 | .588 |
| Andre Pallante | Min | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 6 | .429 | 30 | 15 | 8 | 58.9 | .604 |
| Peyton Pallette | SD | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 4 | 4 | 2 | 21.5 | .686 |
| Mitchell Parker* | Atl | sp | 25 | 2 | 1 | .500 | 1 | .500 | 5 | 23 | 6 | .261 | 48 | 33 | 8 | 39.2 | .619 |
| Joel Payamps | | mr | 31 | 6 | 3 | .500 | 2 | .333 | 14 | 31 | 10 | .323 | 71 | 71 | 14 | 18.4 | .628 |
| Nate Pearson | Hou | mr | 28 | 2 | 0 | .000 | 2 | 1.000 | 0 | 5 | 4 | .800 | 12 | 6 | 1 | 51.5 | .607 |
| Ethan Pecko | Hou | sp | 22 | 1 | 0 | .000 | 1 | 1.000 | 8 | 20 | 5 | .250 | 29 | 24 | 5 | 35.3 | .608 |
| Elvis Peguero | Det | mr | 28 | 4 | 1 | .250 | 3 | .750 | 11 | 51 | 20 | .392 | 74 | 74 | 11 | 19.7 | .600 |
| Walter Pennington* | NYA | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 2 | 9 | 0 | .000 | 10 | 8 | 6 | 43.0 | .600 |
| Ryan Pepiot | KC | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 84.9 | .612 |
| Freddy Peralta | Mia | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 0 | 0 | 86.6 | .598 |
| Wandy Peralta* | SD | mr | 33 | 2 | 2 | 1.000 | 0 | .000 | 5 | 22 | 7 | .318 | 31 | 31 | 11 | 14.0 | .580 |
| Angel Perdomo* | Mia | mr | 31 | 8 | 4 | .500 | 3 | .375 | 9 | 27 | 8 | .296 | 38 | 38 | 11 | 19.1 | .594 |
| Cionel Perez* | | mr | 29 | 5 | 0 | .000 | 4 | .800 | 4 | 22 | 12 | .545 | 37 | 37 | 14 | 17.9 | .596 |
| Eury Perez | Bal | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 92.5 | .609 |
| Martin Perez* | LAN | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 90.5 | .635 |
| Jack Perkins | ChA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 15 | 5 | .333 | 22 | 17 | 8 | 36.9 | .605 |
| David Peterson* | Sac | sp | 29 | 3 | 1 | .333 | 2 | .667 | 9 | 15 | 1 | .067 | 42 | 25 | 6 | 48.1 | .622 |
| Chase Petty | ChA | sp | 22 | 1 | 1 | 1.000 | 0 | .000 | 0 | 16 | 4 | .250 | 23 | 23 | 13 | 35.7 | .604 |
| Brandon Pfaadt | Col | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 92.1 | .635 |
| Evan Phillips | Mil | cl | 30 | 6 | 5 | .833 | 1 | .167 | 0 | 4 | 0 | .000 | 7 | 7 | 6 | 18.9 | .606 |
| Tyler Phillips | Cle | sp | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 1 | .500 | 4 | 4 | 1 | 14.0 | .607 |
| Nick Pivetta | Cle | sp | 32 | 1 | 0 | .000 | 1 | 1.000 | 2 | 14 | 1 | .071 | 36 | 16 | 3 | 59.0 | .621 |
| Drew Pomeranz* | Was | mr | 36 | 2 | 1 | .500 | 1 | .500 | 14 | 22 | 4 | .182 | 52 | 49 | 7 | 20.1 | .593 |
| Cody Poteet | NYN | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 82.9 | .641 |
| Cade Povich* | Bos | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 87.8 | .623 |
| Ryan Pressly | | mr | 36 | 9 | 7 | .778 | 2 | .222 | 8 | 21 | 5 | .238 | 45 | 45 | 20 | 16.3 | .649 |
| Quinn Priester | Ari | sp | 24 | 2 | 1 | .500 | 0 | .000 | 2 | 14 | 6 | .429 | 40 | 20 | 9 | 60.3 | .621 |
| A.J. Puk* | LAN | mr | 30 | 3 | 3 | 1.000 | 0 | .000 | 0 | 2 | 1 | .500 | 5 | 4 | 4 | 28.2 | .603 |
| Jose Quijada* | | mr | 29 | 2 | 1 | .500 | 1 | .500 | 4 | 23 | 6 | .261 | 23 | 21 | 5 | 22.9 | .583 |
| Jose Quintana* | Pit | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 4 | .800 | 18 | 2 | 1 | 85.9 | .608 |
| Cole Ragans* | Was | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 94.9 | .623 |
| Brooks Raley* | Mia | mr | 37 | 4 | 2 | .500 | 2 | .500 | 5 | 11 | 2 | .182 | 16 | 16 | 4 | 13.4 | .593 |
| Drew Rasmussen | Bos | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 94.9 | .637 |
| Dylan Ray | StL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 77.7 | .595 |
| Robbie Ray* | Pit | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 89.0 | .624 |
| Sean Reid-Foley | Atl | mr | 29 | 3 | 1 | .333 | 1 | .333 | 1 | 9 | 4 | .444 | 13 | 13 | 5 | 21.1 | .573 |
| Patrick Reilly | StL | sp | 23 | 3 | 2 | .667 | 1 | .333 | 4 | 10 | 2 | .200 | 20 | 19 | 5 | 23.6 | .572 |
| Eric Reyzelman | | mr | 24 | 4 | 1 | .250 | 3 | .750 | 2 | 15 | 9 | .600 | 28 | 28 | 7 | 21.5 | .619 |
| Trevor Richards | NYN | mr | 32 | 5 | 2 | .400 | 2 | .400 | 9 | 26 | 4 | .154 | 50 | 46 | 12 | 26.5 | .595 |
| Lyon Richardson | NYA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 106.0 | .580 |
| Ethan Roberts | Sac | mr | 27 | 5 | 1 | .200 | 4 | .800 | 4 | 45 | 23 | .511 | 51 | 51 | 16 | 23.8 | .649 |
| David Robertson | Mil | mr | 40 | 8 | 7 | .875 | 1 | .125 | 1 | 24 | 4 | .167 | 22 | 22 | 18 | 18.3 | .617 |
| Tekoah Roby | Sac | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 4 | 1 | 1 | 52.5 | .614 |
| Joe Rock* | Cle | sp | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 10 | 2 | .200 | 20 | 18 | 10 | 27.3 | .600 |
| Kumar Rocker | SD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 21 | 1 | 0 | 82.1 | .639 |
| Carlos Rodon* | | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 92.5 | .629 |
| Carlos F. Rodriguez | | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 19 | 4 | 2 | 76.2 | .596 |
| Eduardo Rodriguez* | Min | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 91.3 | .641 |
| Manuel Rodriguez | Pit | mr | 28 | 5 | 2 | .400 | 3 | .600 | 4 | 12 | 6 | .500 | 25 | 25 | 7 | 21.6 | .612 |
| Randy Rodriguez | Hou | mr | 25 | 4 | 1 | .250 | 1 | .250 | 11 | 37 | 9 | .243 | 61 | 56 | 13 | 27.5 | .597 |
| Wilking Rodriguez | Det | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 6 | 15 | 6 | .400 | 25 | 25 | 3 | 21.6 | .603 |
| Yariel Rodriguez | ChN | sp | 28 | 0 | 0 | .000 | 0 | .000 | 4 | 7 | 4 | .571 | 19 | 12 | 6 | 42.8 | .585 |
| Taylor Rogers* | Ari | mr | 34 | 7 | 3 | .429 | 3 | .429 | 12 | 49 | 22 | .449 | 72 | 72 | 21 | 20.6 | .605 |
| Trevor Rogers* | SF | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 91.2 | .603 |
| Tyler Rogers | Cle | mr | 34 | 19 | 16 | .842 | 3 | .158 | 9 | 33 | 9 | .273 | 60 | 60 | 31 | 15.0 | .659 |
| Drew Rom* | Bos | sp | 25 | 0 | 0 | .000 | 0 | .000 | 2 | 1 | 0 | .000 | 4 | 4 | 0 | 22.8 | .593 |
| Jordan Romano | | cl | 32 | 3 | 1 | .333 | 2 | .667 | 20 | 35 | 13 | .371 | 60 | 60 | 13 | 20.4 | .636 |
| JoJo Romero* | Min | mr | 28 | 8 | 1 | .125 | 5 | .625 | 16 | 35 | 18 | .514 | 67 | 67 | 15 | 19.5 | .629 |
| Landen Roupp | | mr | 26 | 3 | 2 | .667 | 0 | .000 | 1 | 6 | 0 | .000 | 36 | 17 | 9 | 59.3 | .572 |
| Joe Ryan | Min | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 87.7 | .634 |
| Andrew Saalfrank* | Mia | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 5 | 20 | 6 | .300 | 31 | 31 | 6 | 26.4 | .578 |
| Erik Sabrowski* | Pit | mr | 27 | 3 | 1 | .333 | 2 | .667 | 3 | 8 | 2 | .250 | 11 | 11 | 3 | 23.1 | .606 |
| Chris Sale* | LAA | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 94.8 | .653 |
| Cristopher Sanchez* | Tam | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 86.4 | .617 |
| Nick Sandlin | Col | mr | 28 | 0 | 0 | .000 | 0 | .000 | 4 | 8 | 2 | .250 | 14 | 14 | 4 | 17.7 | .653 |
| Cole Sands | | mr | 27 | 16 | 15 | .938 | 1 | .063 | 8 | 44 | 9 | .205 | 64 | 59 | 28 | 30.6 | .615 |
| Dennis Santana | Bal | mr | 29 | 31 | 21 | .677 | 10 | .323 | 4 | 56 | 17 | .304 | 81 | 81 | 64 | 19.0 | .601 |
| Tony Santillan | Col | mr | 28 | 5 | 4 | .800 | 1 | .200 | 5 | 18 | 7 | .389 | 36 | 36 | 15 | 18.9 | .623 |
| Gregory Santos | LAA | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 3 | 0 | .000 | 6 | 6 | 2 | 19.8 | .613 |
| Roki Sasaki | Col | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 88.4 | .621 |
| Tayler Saucedo* | Mil | mr | 32 | 4 | 1 | .250 | 1 | .250 | 4 | 10 | 6 | .600 | 28 | 28 | 4 | 15.6 | .573 |
| Max Scherzer | Cle | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 92.4 | .641 |
| Cam Schlittler | | sp | 24 | 3 | 1 | .333 | 2 | .667 | 7 | 32 | 13 | .406 | 31 | 31 | 7 | 18.1 | .590 |
| Clarke Schmidt | | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 1 | 0 | 91.1 | .597 |
| John Schreiber | | mr | 31 | 2 | 1 | .500 | 1 | .500 | 11 | 26 | 9 | .346 | 48 | 48 | 18 | 18.2 | .610 |
| Noah Schultz* | ChA | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 80.9 | .612 |
| Spencer Schwellenbach | Atl | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 95.0 | .634 |
| Christian Scott | NYA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 103.0 | .595 |
| Tanner Scott* | NYN | cl | 30 | 19 | 18 | .947 | 1 | .053 | 5 | 23 | 1 | .043 | 57 | 57 | 31 | 21.4 | .622 |
| Tayler Scott | Phi | mr | 33 | 4 | 2 | .500 | 2 | .500 | 3 | 18 | 4 | .222 | 31 | 30 | 12 | 20.7 | .633 |
| JP Sears* | Cin | sp | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 2 | 2 | 1 | 22.0 | .727 |
| Kodai Senga | | sp | 32 | 1 | 0 | .000 | 1 | 1.000 | 1 | 3 | 3 | 1.000 | 28 | 5 | 0 | 87.9 | .593 |
| Luis Severino | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 2 | 8 | 3 | .375 | 27 | 15 | 10 | 55.8 | .611 |
| Paul Sewald | Cle | cl | 35 | 3 | 1 | .333 | 1 | .333 | 2 | 9 | 2 | .222 | 12 | 12 | 2 | 18.3 | .655 |
| Carson Seymour | | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 4 | 16 | 4 | .250 | 26 | 24 | 9 | 20.8 | .610 |
| Emmet Sheehan | Ari | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 92.1 | .609 |
| Brady Singer | LAN | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 103.7 | .628 |
| Paul Skenes | SF | sp | 23 | 3 | 1 | .333 | 2 | .667 | 1 | 16 | 6 | .375 | 44 | 16 | 15 | 64.3 | .632 |
| Tarik Skubal* | Tam | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.1 | .661 |
| Justin Slaten | Det | mr | 27 | 9 | 8 | .889 | 0 | .000 | 6 | 42 | 11 | .262 | 56 | 53 | 28 | 22.4 | .639 |
| Ethan Small* | NYN | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 77.0 | .584 |
| Cade Smith | LAA | mr | 26 | 10 | 6 | .600 | 3 | .300 | 27 | 30 | 5 | .167 | 69 | 69 | 20 | 19.9 | .622 |
| Shane Smith | SD | mr | 25 | 2 | 0 | .000 | 2 | 1.000 | 6 | 25 | 10 | .400 | 38 | 38 | 4 | 22.4 | .633 |
| AJ Smith-Shawver | Tex | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 8 | 2 | 1 | 68.9 | .619 |
| Blake Snell* | | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 94.6 | .598 |
| Robby Snelling* | Bal | sp | 21 | 3 | 2 | .667 | 1 | .333 | 2 | 9 | 4 | .444 | 28 | 9 | 6 | 66.1 | .593 |
| Anthony Solometo* | StL | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 7 | 4 | 2 | 39.3 | .607 |
| Jose Soriano | Cin | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 94.0 | .593 |
| Mike Soroka | Ari | sp | 27 | 6 | 3 | .500 | 3 | .500 | 1 | 29 | 6 | .207 | 38 | 38 | 17 | 21.2 | .589 |
| Gregory Soto* | Tam | mr | 30 | 5 | 1 | .200 | 4 | .800 | 11 | 35 | 9 | .257 | 57 | 57 | 12 | 18.7 | .615 |
| Bennett Sousa* | | mr | 30 | 5 | 3 | .600 | 2 | .400 | 7 | 12 | 1 | .083 | 34 | 34 | 14 | 18.4 | .622 |
| Gabe Speier* | Was | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 2 | 15 | 4 | .267 | 30 | 18 | 7 | 47.8 | .622 |
| Mitch Spence | SF | sp | 27 | 2 | 2 | 1.000 | 0 | .000 | 0 | 6 | 2 | .333 | 23 | 11 | 11 | 62.3 | .633 |
| Jeffrey Springs* | Bos | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 84.7 | .633 |
| Brandon Sproat | NYN | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 83.8 | .607 |
| Ryne Stanek | | mr | 33 | 5 | 1 | .200 | 4 | .800 | 17 | 24 | 10 | .417 | 51 | 51 | 12 | 17.2 | .594 |
| Justin Steele* | Tex | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 98.0 | .602 |
| Trevor Stephan | Pit | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 6 | 6 | 2 | 25.0 | .620 |
| Robert Stephenson | | mr | 32 | 2 | 1 | .500 | 1 | .500 | 3 | 4 | 0 | .000 | 8 | 8 | 4 | 17.0 | .640 |
| Brock Stewart | Tex | mr | 33 | 22 | 18 | .818 | 3 | .136 | 5 | 30 | 7 | .233 | 49 | 49 | 36 | 19.2 | .629 |
| Matt Strahm* | | mr | 33 | 8 | 6 | .750 | 2 | .250 | 8 | 9 | 3 | .333 | 48 | 34 | 17 | 40.3 | .669 |
| Hunter Stratton | Mia | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 7 | 17 | 6 | .353 | 31 | 31 | 2 | 21.6 | .590 |
| Spencer Strider | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 96.6 | .635 |
| Marcus Stroman | Pit | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 91.9 | .596 |
| Tyler Stuart | SD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 83.7 | .606 |
| Jose Suarez* | LAA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 1 | .250 | 14 | 14 | 0 | 20.3 | .616 |
| Ranger Suarez* | ChN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 97.7 | .643 |
| Robert Suarez | Tam | cl | 34 | 23 | 19 | .826 | 3 | .130 | 11 | 56 | 16 | .286 | 75 | 75 | 41 | 18.1 | .626 |
| Tomoyuki Sugano | ChN | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 109.0 | .615 |
| Brent Suter* | LAN | mr | 35 | 1 | 1 | 1.000 | 0 | .000 | 9 | 26 | 7 | .269 | 49 | 44 | 13 | 28.6 | .640 |
| Erik Swanson | Tor | mr | 31 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 6 | 6 | 2 | 24.8 | .624 |
| Jameson Taillon | Tam | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 89.6 | .643 |
| Dillon Tate | Tex | mr | 31 | 1 | 0 | .000 | 1 | 1.000 | 2 | 8 | 5 | .625 | 11 | 11 | 3 | 16.1 | .616 |
| Troy Taylor | SF | mr | 23 | 6 | 3 | .500 | 3 | .500 | 4 | 28 | 11 | .393 | 38 | 38 | 12 | 27.0 | .588 |
| Kai-Wei Teng | Hou | sp | 26 | 1 | 0 | .000 | 1 | 1.000 | 3 | 12 | 5 | .417 | 16 | 16 | 5 | 20.9 | .572 |
| Emiliano Teodo | Tex | sp | 24 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 1 | .500 | 2 | 2 | 2 | 20.5 | .561 |
| Caleb Thielbar* | | mr | 38 | 8 | 5 | .625 | 3 | .375 | 18 | 25 | 7 | .280 | 59 | 59 | 16 | 18.4 | .618 |
| Keegan Thompson | Det | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 91.5 | .595 |
| Ryan Thompson | Bos | mr | 33 | 5 | 2 | .400 | 3 | .600 | 18 | 17 | 7 | .412 | 50 | 50 | 11 | 21.1 | .641 |
| Trent Thornton | Mil | mr | 31 | 4 | 2 | .500 | 2 | .500 | 6 | 13 | 8 | .615 | 28 | 28 | 8 | 18.9 | .652 |
| Blade Tidwell | Mil | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 0 | .000 | 6 | 6 | 3 | 29.2 | .577 |
| Jesus Tinoco | Atl | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 9 | 7 | 3 | .429 | 23 | 23 | 5 | 23.4 | .575 |
| Jonah Tong | Bos | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 3 | 2 | 1 | 46.0 | .616 |
| Michael Tonkin | NYA | mr | 35 | 2 | 2 | 1.000 | 0 | .000 | 0 | 6 | 2 | .333 | 8 | 8 | 3 | 40.5 | .574 |
| Justin Topa | | mr | 34 | 2 | 2 | 1.000 | 0 | .000 | 11 | 24 | 7 | .292 | 41 | 41 | 14 | 21.3 | .611 |
| Blake Treinen | | mr | 37 | 6 | 4 | .667 | 2 | .333 | 1 | 8 | 2 | .250 | 16 | 16 | 8 | 17.4 | .631 |
| Edwin Uceta | | mr | 27 | 18 | 17 | .944 | 0 | .000 | 10 | 34 | 10 | .294 | 68 | 68 | 42 | 22.8 | .616 |
| Miguel Ullola | StL | sp | 23 | 8 | 2 | .250 | 5 | .625 | 16 | 70 | 38 | .543 | 102 | 101 | 15 | 18.0 | .568 |
| Abner Uribe | Sea | mr | 25 | 3 | 2 | .667 | 0 | .000 | 9 | 40 | 11 | .275 | 52 | 52 | 13 | 21.2 | .574 |
| Jose Urquidy | Cle | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 1 | 1 | 0 | 35.0 | .714 |
| Framber Valdez* | LAA | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 107.2 | .612 |
| CJ Van Eyk | LAN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 89.0 | .610 |
| Carlos Vargas | Sea | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 4 | 4 | 3 | 21.3 | .635 |
| Louie Varland | Atl | sp | 27 | 4 | 3 | .750 | 1 | .250 | 15 | 40 | 10 | .250 | 69 | 68 | 25 | 19.9 | .636 |
| Mike Vasil | SD | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 2 | 7 | 0 | .000 | 17 | 12 | 3 | 44.2 | .618 |
| Randy Vasquez | NYA | sp | 26 | 2 | 0 | .000 | 2 | 1.000 | 1 | 5 | 3 | .600 | 26 | 6 | 0 | 64.5 | .597 |
| Justin Verlander | | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 96.4 | .628 |
| Alex Vesia* | Atl | mr | 29 | 30 | 20 | .667 | 10 | .333 | 2 | 30 | 4 | .133 | 54 | 54 | 41 | 21.4 | .611 |
| Will Vest | Sac | mr | 30 | 20 | 12 | .600 | 7 | .350 | 14 | 46 | 10 | .217 | 77 | 77 | 37 | 16.1 | .607 |
| Victor Vodnik | LAA | mr | 25 | 4 | 1 | .250 | 3 | .750 | 2 | 18 | 5 | .278 | 27 | 27 | 13 | 21.1 | .589 |
| Michael Wacha | | sp | 33 | 3 | 0 | .000 | 3 | 1.000 | 0 | 8 | 6 | .750 | 36 | 12 | 6 | 69.6 | .625 |
| Hurston Waldrep | Atl | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 78.6 | .577 |
| Josh Walker* | Cin | mr | 30 | 3 | 3 | 1.000 | 0 | .000 | 5 | 20 | 9 | .450 | 29 | 29 | 15 | 23.1 | .625 |
| Ryan Walker | Phi | mr | 29 | 26 | 23 | .885 | 3 | .115 | 0 | 19 | 2 | .105 | 51 | 51 | 45 | 16.6 | .638 |
| Andrew Walters | Mia | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 0 | 35.5 | .563 |
| Will Warren | ChN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 97.0 | .624 |
| Ryan Weathers* | Col | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 1 | 0 | 77.7 | .619 |
| Luke Weaver | Tam | mr | 31 | 8 | 5 | .625 | 3 | .375 | 12 | 45 | 13 | .289 | 63 | 63 | 20 | 22.0 | .604 |
| Jacob Webb | Mil | mr | 31 | 4 | 1 | .250 | 3 | .750 | 19 | 44 | 10 | .227 | 73 | 73 | 11 | 20.2 | .604 |
| Logan Webb | Sac | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 95.6 | .636 |
| Greg Weissert | Mia | mr | 30 | 4 | 0 | .000 | 4 | 1.000 | 12 | 19 | 5 | .263 | 56 | 56 | 17 | 20.3 | .625 |
| Tyler Wells | NYA | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 98.2 | .668 |
| Hayden Wesneski | NYA | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 13 | 5 | 5 | 73.8 | .610 |
| Cameron Weston | Tor | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 19 | 5 | 1 | 77.1 | .615 |
| Zack Wheeler | Phi | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 109.9 | .628 |
| Carson Whisenhunt* | KC | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 11 | 1 | 1 | 79.3 | .615 |
| Forrest Whitley | Cin | mr | 27 | 3 | 1 | .333 | 1 | .333 | 1 | 15 | 4 | .267 | 16 | 16 | 6 | 13.5 | .569 |
| Garrett Whitlock | Sac | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 93.0 | .646 |
| Jordan Wicks* | | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 3 | 2 | 0 | 55.3 | .566 |
| Nathan Wiles | Bal | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 5 | 16 | 3 | .188 | 27 | 27 | 1 | 17.8 | .682 |
| Devin Williams | Min | cl | 30 | 33 | 29 | .879 | 4 | .121 | 1 | 23 | 1 | .043 | 54 | 54 | 46 | 18.6 | .623 |
| Gavin Williams | Ari | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 84.6 | .610 |
| Allan Winans | SD | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 18 | 5 | 2 | 69.6 | .623 |
| Josh Winckowski | KC | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 90.1 | .633 |
| Keaton Winn | SF | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 88.0 | .750 |
| Bryan Woo | Pit | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 84.5 | .649 |
| Brandon Woodruff | Bos | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 102.6 | .630 |
| Jaden Woods* | SF | mr | 23 | 4 | 1 | .250 | 3 | .750 | 8 | 8 | 4 | .500 | 27 | 27 | 7 | 20.9 | .607 |
| Simeon Woods Richardso | Pit | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 82.1 | .618 |
| Kyle Wright | Col | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 115.5 | .645 |
| Justin Wrobleski* | Atl | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 3 | 1 | 0 | .000 | 13 | 12 | 5 | 28.4 | .610 |
| Yoshinobu Yamamoto | Col | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 100.5 | .651 |
| Ryan Yarbrough* | NYA | mr | 33 | 6 | 2 | .333 | 3 | .500 | 2 | 9 | 4 | .444 | 36 | 21 | 9 | 53.6 | .604 |
| Kirby Yates | Min | cl | 38 | 4 | 2 | .500 | 2 | .500 | 9 | 26 | 10 | .385 | 49 | 49 | 7 | 21.2 | .578 |
| Craig Yoho | Bos | mr | 25 | 4 | 3 | .750 | 1 | .250 | 23 | 48 | 17 | .354 | 69 | 69 | 20 | 20.6 | .590 |
| Brandon Young | Mia | sp | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 0 | .000 | 9 | 7 | 4 | 36.7 | .627 |
| Rob Zastryzny* | | mr | 33 | 1 | 1 | 1.000 | 0 | .000 | 6 | 20 | 5 | .250 | 34 | 25 | 7 | 35.1 | .614 |
| Ryan Zeferjahn | | mr | 27 | 8 | 5 | .625 | 3 | .375 | 17 | 37 | 10 | .270 | 68 | 68 | 25 | 22.4 | .585 |
| Angel Zerpa* | | mr | 25 | 6 | 2 | .333 | 4 | .667 | 2 | 23 | 8 | .348 | 27 | 27 | 10 | 19.6 | .631 |
