Org pitching register -- Inter-league
Regular season -- as of 10/20/2024
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| Andrew Abbott* | | sp | 25 | 4.21 | 12 | 8 | 0 | 27 | 27 | 0 | 0 | 156.0 | 161 | 81 | 73 | 50 | 177 | 23 | 9 |
| Mick Abel | Sea | sp | 22 | 3.48 | 2 | 4 | 0 | 6 | 6 | 0 | 0 | 33.2 | 37 | 14 | 13 | 11 | 39 | 5 | 2 |
| Bryan Abreu | Sea | mr | 27 | 2.30 | 4 | 1 | 2 | 65 | 0 | 0 | 0 | 82.1 | 50 | 26 | 21 | 33 | 121 | 6 | 9 |
| Jason Adam | Ari | mr | 32 | 2.92 | 3 | 5 | 8 | 65 | 0 | 0 | 0 | 86.1 | 51 | 30 | 28 | 26 | 95 | 12 | 4 |
| Austin L. Adams | Hou | mr | 33 | 5.91 | 0 | 0 | 0 | 12 | 0 | 0 | 0 | 10.2 | 8 | 7 | 7 | 9 | 15 | 1 | 1 |
| Ty Adcock | Det | mr | 27 | 2.45 | 3 | 6 | 32 | 61 | 0 | 0 | 0 | 66.0 | 56 | 20 | 18 | 11 | 67 | 7 | 5 |
| Keegan Akin* | LAA | mr | 29 | 3.94 | 2 | 2 | 4 | 43 | 0 | 0 | 0 | 48.0 | 52 | 23 | 21 | 17 | 54 | 7 | 0 |
| Jorge Alcala | Bal | mr | 28 | 2.97 | 8 | 9 | 15 | 87 | 0 | 0 | 0 | 109.0 | 81 | 42 | 36 | 35 | 113 | 10 | 15 |
| Franco Aleman | Col | mr | 24 | 4.20 | 2 | 5 | 3 | 33 | 2 | 0 | 0 | 49.1 | 53 | 33 | 23 | 18 | 54 | 4 | 3 |
| Scott Alexander* | | mr | 34 | 8.27 | 1 | 1 | 0 | 8 | 3 | 0 | 0 | 16.1 | 25 | 16 | 15 | 3 | 12 | 4 | 0 |
| Tyler Alexander* | ChA | mr | 29 | 4.60 | 11 | 14 | 0 | 33 | 31 | 1 | 0 | 205.1 | 225 | 112 | 105 | 21 | 187 | 42 | 12 |
| Logan T. Allen* | Was | sp | 25 | 3.63 | 9 | 9 | 1 | 28 | 24 | 0 | 0 | 163.2 | 158 | 78 | 66 | 42 | 133 | 17 | 18 |
| Jose Alvarado* | Ari | mr | 29 | 1.95 | 6 | 7 | 26 | 55 | 0 | 0 | 0 | 60.0 | 43 | 27 | 13 | 28 | 92 | 3 | 3 |
| Adbert Alzolay | ChN | cl | 29 | 4.60 | 3 | 3 | 0 | 10 | 10 | 0 | 0 | 60.2 | 56 | 31 | 31 | 10 | 62 | 7 | 5 |
| Ian Anderson | Atl | sp | 26 | 4.64 | 3 | 6 | 0 | 13 | 13 | 0 | 0 | 75.2 | 84 | 45 | 39 | 43 | 62 | 6 | 6 |
| Nick Anderson | Was | mr | 33 | 4.45 | 3 | 4 | 3 | 40 | 0 | 0 | 0 | 58.2 | 52 | 30 | 29 | 10 | 64 | 12 | 2 |
| Tyler Anderson* | | sp | 34 | 4.32 | 12 | 11 | 0 | 28 | 28 | 3 | 2 | 183.1 | 185 | 95 | 88 | 32 | 166 | 32 | 15 |
| Luarbert Arias | Col | mr | 23 | 7.23 | 5 | 4 | 3 | 79 | 2 | 0 | 0 | 107.0 | 141 | 94 | 86 | 35 | 110 | 15 | 7 |
| Shawn Armstrong | Ari | mr | 33 | 2.98 | 17 | 2 | 0 | 32 | 32 | 0 | 0 | 178.1 | 136 | 63 | 59 | 46 | 181 | 16 | 10 |
| Spencer Arrighetti | | sp | 24 | 4.71 | 8 | 10 | 0 | 38 | 27 | 0 | 0 | 166.1 | 166 | 94 | 87 | 60 | 154 | 29 | 11 |
| Aaron Ashby* | SD | sp | 26 | 2.41 | 3 | 2 | 4 | 27 | 1 | 0 | 0 | 37.1 | 26 | 13 | 10 | 9 | 40 | 4 | 2 |
| Braxton Ashcraft | Atl | sp | 24 | 4.92 | 3 | 7 | 0 | 20 | 20 | 0 | 0 | 104.1 | 123 | 62 | 57 | 24 | 79 | 11 | 6 |
| Graham Ashcraft | Was | sp | 26 | 3.80 | 8 | 9 | 1 | 23 | 22 | 4 | 1 | 156.1 | 140 | 76 | 66 | 36 | 112 | 18 | 10 |
| Pedro Avila | | sp | 27 | 4.24 | 3 | 0 | 1 | 14 | 1 | 0 | 0 | 23.1 | 19 | 12 | 11 | 4 | 23 | 2 | 1 |
| Anthony Banda* | Mia | mr | 30 | 3.60 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 5.0 | 5 | 2 | 2 | 2 | 3 | 1 | 1 |
| Tanner Banks* | Tam | mr | 32 | 2.49 | 3 | 5 | 13 | 52 | 0 | 0 | 0 | 76.0 | 57 | 28 | 21 | 17 | 75 | 11 | 4 |
| Scott Barlow | ChN | mr | 31 | 5.05 | 4 | 4 | 3 | 47 | 0 | 0 | 0 | 62.1 | 58 | 37 | 35 | 24 | 76 | 9 | 3 |
| Jaime Barria | ChN | mr | 27 | 3.19 | 2 | 0 | 0 | 25 | 0 | 0 | 0 | 48.0 | 42 | 17 | 17 | 6 | 36 | 8 | 2 |
| Chris Bassitt | Mil | sp | 35 | 2.73 | 17 | 8 | 0 | 33 | 33 | 6 | 1 | 240.1 | 188 | 76 | 73 | 35 | 216 | 27 | 12 |
| Brady Basso* | Min | sp | 26 | 6.07 | 1 | 3 | 0 | 35 | 0 | 0 | 0 | 29.2 | 42 | 20 | 20 | 6 | 28 | 6 | 2 |
| Mike Baumann | Bal | mr | 28 | 2.63 | 1 | 1 | 2 | 17 | 0 | 0 | 0 | 24.0 | 16 | 11 | 7 | 15 | 21 | 3 | 4 |
| Jarod Bayless | Phi | mr | 27 | 9.00 | 1 | 1 | 1 | 9 | 0 | 0 | 0 | 11.0 | 13 | 11 | 11 | 7 | 9 | 3 | 1 |
| Shane Baz | Bal | sp | 25 | 4.31 | 4 | 10 | 0 | 38 | 29 | 0 | 0 | 165.0 | 148 | 83 | 79 | 58 | 171 | 25 | 5 |
| Eduard Bazardo | Pit | mr | 28 | 5.82 | 1 | 3 | 0 | 9 | 6 | 0 | 0 | 34.0 | 36 | 26 | 22 | 11 | 36 | 4 | 2 |
| David Bednar | Tam | cl | 29 | 3.19 | 10 | 3 | 17 | 49 | 0 | 0 | 0 | 59.1 | 47 | 28 | 21 | 26 | 70 | 7 | 4 |
| Jalen Beeks* | LAN | mr | 30 | 5.20 | 3 | 2 | 2 | 52 | 0 | 0 | 0 | 100.1 | 104 | 58 | 58 | 29 | 92 | 15 | 9 |
| Clayton Beeter | NYA | sp | 25 | 4.63 | 6 | 5 | 0 | 26 | 10 | 0 | 0 | 68.0 | 69 | 39 | 35 | 34 | 68 | 10 | 5 |
| Brayan Bello | Mil | sp | 25 | 4.60 | 11 | 11 | 0 | 31 | 31 | 1 | 1 | 188.0 | 196 | 105 | 96 | 57 | 152 | 24 | 15 |
| Anthony Bender | Mil | mr | 29 | 3.39 | 9 | 13 | 0 | 33 | 26 | 0 | 0 | 175.1 | 149 | 75 | 66 | 30 | 173 | 28 | 16 |
| Brennan Bernardino* | NYA | mr | 32 | 4.74 | 0 | 1 | 0 | 18 | 1 | 0 | 0 | 19.0 | 16 | 11 | 10 | 8 | 18 | 4 | 0 |
| Jose Berrios | Tor | sp | 30 | 4.50 | 7 | 14 | 0 | 31 | 31 | 4 | 1 | 208.0 | 215 | 120 | 104 | 38 | 205 | 36 | 13 |
| Prelander Berroa | SF | mr | 24 | 8.89 | 6 | 10 | 3 | 74 | 9 | 0 | 0 | 84.0 | 99 | 88 | 83 | 90 | 88 | 16 | 8 |
| Tanner Bibee | Was | sp | 25 | 5.38 | 7 | 13 | 0 | 24 | 24 | 0 | 0 | 144.0 | 148 | 96 | 86 | 51 | 144 | 23 | 5 |
| Phil Bickford | Mil | mr | 28 | 4.21 | 2 | 1 | 2 | 37 | 0 | 0 | 0 | 36.1 | 37 | 22 | 17 | 16 | 31 | 4 | 4 |
| Osvaldo Bido | Mia | sp | 28 | 4.66 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 9.2 | 7 | 5 | 5 | 5 | 8 | 1 | 1 |
| Shane Bieber | Tor | sp | 29 | 1.69 | 1 | 0 | 0 | 2 | 2 | 1 | 0 | 16.0 | 10 | 3 | 3 | 2 | 14 | 0 | 2 |
| Hunter Bigge | Sea | mr | 26 | 9.50 | 0 | 1 | 2 | 14 | 0 | 0 | 0 | 18.0 | 27 | 20 | 19 | 8 | 26 | 4 | 0 |
| Hayden Birdsong | Bos | sp | 22 | 4.90 | 3 | 2 | 0 | 32 | 10 | 0 | 0 | 71.2 | 61 | 39 | 39 | 36 | 68 | 8 | 5 |
| Mason Black | Min | sp | 24 | 7.20 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 5.0 | 7 | 5 | 4 | 3 | 6 | 2 | 0 |
| Ronel Blanco | Col | mr | 30 | 4.43 | 4 | 6 | 2 | 47 | 17 | 0 | 0 | 142.1 | 144 | 74 | 70 | 41 | 143 | 20 | 9 |
| Jonathan Bowlan | SF | sp | 27 | 5.99 | 4 | 6 | 5 | 51 | 8 | 0 | 0 | 88.2 | 104 | 63 | 59 | 33 | 63 | 16 | 9 |
| Joe Boyle | NYA | sp | 24 | 4.48 | 0 | 6 | 4 | 31 | 11 | 0 | 0 | 80.1 | 62 | 54 | 40 | 59 | 100 | 13 | 4 |
| Cody Bradford* | Tam | sp | 26 | 6.14 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 7.1 | 11 | 6 | 5 | 1 | 5 | 0 | 1 |
| Kyle Bradish | Bal | sp | 27 | 3.86 | 5 | 2 | 0 | 8 | 8 | 0 | 0 | 51.1 | 47 | 22 | 22 | 15 | 41 | 8 | 7 |
| Taj Bradley | | sp | 23 | 4.80 | 8 | 9 | 0 | 26 | 26 | 0 | 0 | 138.2 | 130 | 77 | 74 | 54 | 129 | 19 | 5 |
| Ryan Brasier | Pit | mr | 36 | 3.82 | 0 | 1 | 1 | 20 | 0 | 0 | 0 | 30.2 | 29 | 14 | 13 | 5 | 27 | 4 | 2 |
| Huascar Brazoban | NYN | mr | 34 | 6.17 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 11.2 | 15 | 8 | 8 | 3 | 8 | 4 | 2 |
| John Brebbia | ChA | mr | 34 | 0.00 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 1.2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 |
| Beau Brieske | StL | mr | 26 | 5.54 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 13.0 | 11 | 9 | 8 | 2 | 5 | 5 | 0 |
| Trevor Brigden | Cin | mr | 28 | 2.80 | 1 | 0 | 1 | 32 | 0 | 0 | 0 | 35.1 | 27 | 12 | 11 | 18 | 36 | 4 | 5 |
| Jhony Brito | ChA | sp | 26 | 4.11 | 10 | 12 | 1 | 63 | 17 | 0 | 0 | 140.0 | 153 | 70 | 64 | 36 | 122 | 17 | 15 |
| Kyle Brnovich | StL | sp | 26 | 4.17 | 6 | 6 | 0 | 23 | 20 | 0 | 0 | 108.0 | 98 | 54 | 50 | 24 | 105 | 12 | 4 |
| T.J. Brock | Phi | mr | 24 | 2.55 | 3 | 3 | 2 | 13 | 0 | 0 | 0 | 17.2 | 16 | 10 | 5 | 5 | 13 | 0 | 0 |
| Ben Brown | Sea | sp | 24 | 5.64 | 4 | 6 | 0 | 16 | 16 | 0 | 0 | 81.1 | 90 | 52 | 51 | 27 | 91 | 14 | 7 |
| Hunter Brown | Hou | sp | 25 | 4.50 | 10 | 11 | 0 | 35 | 34 | 0 | 0 | 212.0 | 207 | 110 | 106 | 68 | 230 | 26 | 16 |
| Zach Brzykcy | Phi | mr | 24 | 5.59 | 5 | 3 | 3 | 50 | 1 | 0 | 0 | 67.2 | 73 | 49 | 42 | 41 | 77 | 14 | 7 |
| Kris Bubic* | Tex | sp | 26 | 4.30 | 3 | 3 | 4 | 19 | 5 | 0 | 0 | 44.0 | 30 | 23 | 21 | 17 | 41 | 6 | 4 |
| Walker Buehler | LAA | sp | 29 | 3.38 | 8 | 4 | 0 | 17 | 17 | 0 | 0 | 106.2 | 93 | 40 | 40 | 21 | 111 | 14 | 5 |
| Aaron Bummer* | Oak | mr | 30 | 3.99 | 1 | 5 | 2 | 40 | 0 | 0 | 0 | 38.1 | 42 | 19 | 17 | 23 | 52 | 4 | 2 |
| Brock Burke* | SD | mr | 27 | 3.72 | 4 | 3 | 2 | 36 | 0 | 0 | 0 | 46.0 | 43 | 21 | 19 | 4 | 44 | 7 | 3 |
| Sean Burke | LAA | sp | 24 | 9.00 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 6.0 | 5 | 6 | 6 | 7 | 3 | 2 | 1 |
| Corbin Burnes | Ari | sp | 29 | 3.18 | 15 | 14 | 0 | 36 | 36 | 5 | 1 | 263.0 | 213 | 99 | 93 | 79 | 301 | 23 | 13 |
| Mike Burrows | Tex | sp | 24 | 6.89 | 0 | 4 | 1 | 12 | 5 | 0 | 0 | 31.1 | 37 | 26 | 24 | 10 | 26 | 9 | 2 |
| Jose Butto | Sea | sp | 26 | 6.63 | 1 | 9 | 1 | 25 | 12 | 0 | 0 | 73.1 | 89 | 56 | 54 | 31 | 55 | 15 | 5 |
| Edward Cabrera | Atl | sp | 26 | 5.40 | 4 | 6 | 1 | 17 | 7 | 0 | 0 | 46.2 | 46 | 35 | 28 | 16 | 50 | 4 | 3 |
| Genesis Cabrera* | Tam | mr | 27 | 1.82 | 4 | 2 | 0 | 63 | 0 | 0 | 0 | 74.0 | 53 | 21 | 15 | 22 | 80 | 4 | 2 |
| Isaiah Campbell | Ari | mr | 26 | 5.47 | 0 | 1 | 1 | 20 | 0 | 0 | 0 | 24.2 | 27 | 15 | 15 | 4 | 28 | 8 | 5 |
| Griffin Canning | Cin | sp | 28 | 3.77 | 8 | 4 | 0 | 22 | 18 | 0 | 0 | 105.0 | 93 | 45 | 44 | 42 | 104 | 10 | 5 |
| Yennier Cano | ChN | mr | 30 | 2.65 | 7 | 6 | 30 | 68 | 0 | 0 | 0 | 78.0 | 63 | 31 | 23 | 16 | 73 | 9 | 5 |
| Joey Cantillo* | SF | sp | 24 | 4.64 | 8 | 11 | 3 | 82 | 13 | 0 | 0 | 145.1 | 139 | 87 | 75 | 85 | 146 | 14 | 11 |
| Luis Castillo | Bos | sp | 31 | 2.60 | 18 | 7 | 0 | 30 | 30 | 4 | 2 | 221.1 | 182 | 68 | 64 | 52 | 221 | 15 | 8 |
| Miguel Castro | Min | mr | 29 | 2.41 | 3 | 5 | 2 | 31 | 0 | 0 | 0 | 37.1 | 20 | 13 | 10 | 19 | 39 | 4 | 1 |
| Tim Cate* | LAN | mr | 26 | 4.26 | 0 | 0 | 0 | 24 | 0 | 0 | 0 | 25.1 | 22 | 12 | 12 | 11 | 16 | 3 | 2 |
| Dylan Cease | Mil | sp | 28 | 4.46 | 10 | 16 | 0 | 33 | 33 | 3 | 1 | 214.0 | 197 | 111 | 106 | 90 | 266 | 30 | 5 |
| Slade Cecconi | SD | sp | 25 | 2.65 | 12 | 11 | 0 | 31 | 31 | 1 | 0 | 214.1 | 176 | 78 | 63 | 38 | 172 | 24 | 10 |
| Andrew Chafin* | Oak | mr | 34 | 3.00 | 2 | 3 | 1 | 38 | 0 | 0 | 0 | 42.0 | 35 | 19 | 14 | 13 | 35 | 6 | 3 |
| Chandler Champlain | | sp | 24 | 5.79 | 5 | 3 | 1 | 22 | 12 | 0 | 0 | 87.0 | 98 | 65 | 56 | 31 | 65 | 13 | 5 |
| Aroldis Chapman* | LAA | mr | 36 | 2.70 | 3 | 5 | 11 | 60 | 0 | 0 | 0 | 56.2 | 31 | 23 | 17 | 35 | 88 | 8 | 1 |
| Jesse Chavez | ChA | mr | 40 | 5.28 | 2 | 7 | 8 | 79 | 5 | 0 | 0 | 92.0 | 98 | 63 | 54 | 35 | 84 | 25 | 4 |
| Aaron Civale | Min | sp | 29 | 4.64 | 13 | 7 | 0 | 26 | 26 | 0 | 0 | 161.0 | 161 | 85 | 83 | 36 | 145 | 23 | 7 |
| Emmanuel Clase | Sea | cl | 26 | 2.74 | 6 | 7 | 21 | 54 | 0 | 0 | 0 | 65.2 | 58 | 28 | 20 | 14 | 87 | 1 | 2 |
| Garrett Cleavinger* | Ari | mr | 30 | 3.95 | 8 | 4 | 4 | 66 | 0 | 0 | 0 | 73.0 | 58 | 33 | 32 | 30 | 104 | 10 | 7 |
| Alex Cobb | SD | sp | 36 | 3.94 | 3 | 2 | 0 | 5 | 5 | 0 | 0 | 32.0 | 37 | 14 | 14 | 4 | 26 | 3 | 2 |
| Isaac Coffey | Cin | sp | 24 | 3.12 | 13 | 5 | 0 | 24 | 24 | 1 | 0 | 155.2 | 122 | 60 | 54 | 44 | 129 | 14 | 6 |
| Gerrit Cole | Oak | sp | 33 | 4.33 | 5 | 6 | 0 | 17 | 17 | 2 | 1 | 108.0 | 99 | 59 | 52 | 31 | 118 | 16 | 3 |
| Luis Contreras | StL | mr | 28 | 4.07 | 2 | 0 | 0 | 22 | 0 | 0 | 0 | 42.0 | 38 | 26 | 19 | 16 | 43 | 7 | 1 |
| Roansy Contreras | Det | sp | 24 | 2.88 | 16 | 7 | 0 | 35 | 35 | 1 | 0 | 200.1 | 164 | 72 | 64 | 55 | 207 | 17 | 11 |
| Connor Cooke | Pit | mr | 24 | 6.01 | 3 | 9 | 0 | 47 | 13 | 0 | 0 | 109.1 | 115 | 84 | 73 | 46 | 125 | 17 | 5 |
| Nestor Cortes* | | sp | 29 | 3.05 | 20 | 10 | 0 | 34 | 34 | 2 | 1 | 224.1 | 181 | 83 | 76 | 46 | 202 | 23 | 18 |
| Tom Cosgrove* | | mr | 28 | 4.15 | 1 | 1 | 1 | 7 | 0 | 0 | 0 | 8.2 | 8 | 4 | 4 | 3 | 7 | 2 | 0 |
| Danny Coulombe* | Det | mr | 34 | 4.35 | 2 | 0 | 0 | 11 | 0 | 0 | 0 | 10.1 | 15 | 5 | 5 | 0 | 19 | 0 | 0 |
| Jake Cousins | Mil | mr | 29 | 6.75 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 5.1 | 2 | 4 | 4 | 4 | 6 | 1 | 0 |
| Austin Cox* | ChA | sp | 27 | 4.30 | 0 | 2 | 4 | 22 | 4 | 0 | 0 | 52.1 | 48 | 26 | 25 | 16 | 45 | 7 | 3 |
| Kutter Crawford | Det | sp | 28 | 5.00 | 8 | 9 | 0 | 21 | 21 | 0 | 0 | 111.2 | 115 | 66 | 62 | 22 | 102 | 20 | 7 |
| Garrett Crochet* | | mr | 25 | 4.17 | 7 | 7 | 3 | 51 | 0 | 0 | 0 | 58.1 | 51 | 36 | 27 | 26 | 67 | 6 | 5 |
| Declan Cronin | | mr | 26 | 5.43 | 5 | 3 | 3 | 59 | 0 | 0 | 0 | 61.1 | 81 | 42 | 37 | 19 | 46 | 10 | 9 |
| Hans Crouse | Sea | sp | 25 | 6.75 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.1 | 1 | 1 | 1 | 1 | 2 | 1 | 0 |
| Fernando Cruz | | mr | 34 | 1.93 | 0 | 1 | 1 | 15 | 0 | 0 | 0 | 18.2 | 11 | 5 | 4 | 7 | 27 | 1 | 3 |
| Hagen Danner | Cin | mr | 25 | 3.69 | 5 | 0 | 4 | 26 | 0 | 0 | 0 | 31.2 | 28 | 14 | 13 | 13 | 29 | 1 | 5 |
| Yu Darvish | | sp | 37 | 2.60 | 9 | 2 | 0 | 16 | 16 | 1 | 0 | 110.2 | 83 | 35 | 32 | 16 | 103 | 12 | 4 |
| Enyel De Los Santos | Mil | mr | 28 | 4.00 | 3 | 6 | 6 | 47 | 0 | 0 | 0 | 54.0 | 47 | 29 | 24 | 20 | 51 | 11 | 4 |
| Jacob deGrom | Cle | sp | 36 | 0.49 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 18.1 | 8 | 2 | 1 | 6 | 26 | 0 | 0 |
| Reid Detmers* | | sp | 24 | 4.02 | 12 | 6 | 0 | 32 | 32 | 0 | 0 | 197.0 | 175 | 92 | 88 | 48 | 196 | 30 | 21 |
| Chris Devenski | ChN | mr | 33 | 2.29 | 11 | 3 | 0 | 20 | 20 | 1 | 1 | 117.2 | 88 | 37 | 30 | 20 | 112 | 10 | 2 |
| Alexis Diaz | | cl | 27 | 3.97 | 2 | 4 | 1 | 51 | 0 | 0 | 0 | 59.0 | 36 | 29 | 26 | 21 | 77 | 3 | 2 |
| Edwin Diaz | | cl | 30 | 3.62 | 2 | 6 | 26 | 49 | 0 | 0 | 0 | 54.2 | 43 | 27 | 22 | 20 | 79 | 5 | 6 |
| Miguel Diaz | SD | mr | 29 | 5.63 | 1 | 0 | 0 | 27 | 0 | 0 | 0 | 38.1 | 47 | 27 | 24 | 15 | 38 | 5 | 5 |
| Yilber Diaz | | sp | 23 | 7.08 | 1 | 5 | 0 | 11 | 9 | 0 | 0 | 48.1 | 50 | 39 | 38 | 19 | 43 | 10 | 5 |
| Jake Diekman* | SD | mr | 37 | 6.00 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 3.0 | 3 | 2 | 2 | 3 | 4 | 1 | 0 |
| Hunter Dobbins | Sea | sp | 24 | 3.98 | 1 | 5 | 0 | 9 | 9 | 0 | 0 | 52.0 | 60 | 27 | 23 | 8 | 38 | 8 | 4 |
| Seranthony Dominguez | Was | mr | 29 | 4.73 | 3 | 3 | 5 | 57 | 0 | 0 | 0 | 72.1 | 63 | 42 | 38 | 35 | 80 | 8 | 14 |
| Camilo Doval | Oak | cl | 26 | 2.60 | 6 | 5 | 30 | 56 | 0 | 0 | 0 | 65.2 | 60 | 30 | 19 | 21 | 83 | 5 | 3 |
| Shawn Dubin | Was | sp | 28 | 3.28 | 4 | 4 | 1 | 16 | 11 | 0 | 0 | 68.2 | 62 | 27 | 25 | 21 | 71 | 10 | 2 |
| Dane Dunning | LAA | sp | 29 | 4.67 | 5 | 4 | 4 | 42 | 19 | 0 | 0 | 144.2 | 149 | 82 | 75 | 45 | 114 | 21 | 13 |
| Jhoan Duran | Sea | cl | 26 | 2.19 | 6 | 2 | 5 | 46 | 0 | 0 | 0 | 61.2 | 53 | 16 | 15 | 15 | 93 | 2 | 2 |
| Jake Eder* | Tex | sp | 25 | 6.36 | 2 | 4 | 0 | 17 | 10 | 0 | 0 | 58.0 | 66 | 41 | 41 | 32 | 59 | 16 | 1 |
| Scott Effross | Det | mr | 30 | 1.57 | 2 | 1 | 3 | 20 | 0 | 0 | 0 | 28.2 | 17 | 6 | 5 | 5 | 23 | 1 | 1 |
| Zach Eflin | | sp | 30 | 4.22 | 7 | 9 | 0 | 27 | 27 | 1 | 1 | 160.0 | 191 | 80 | 75 | 23 | 178 | 12 | 8 |
| Brandon Eisert* | Det | mr | 26 | 2.99 | 7 | 4 | 1 | 21 | 11 | 0 | 0 | 81.1 | 73 | 33 | 27 | 18 | 82 | 10 | 4 |
| Bryce Elder | | sp | 25 | 4.16 | 8 | 16 | 0 | 33 | 33 | 3 | 0 | 205.2 | 192 | 102 | 95 | 68 | 170 | 18 | 18 |
| Fraser Ellard* | Sea | mr | 26 | 9.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2.0 | 2 | 3 | 2 | 4 | 4 | 0 | 0 |
| Nic Enright | | mr | 27 | 5.48 | 0 | 3 | 1 | 15 | 0 | 0 | 0 | 23.0 | 25 | 19 | 14 | 6 | 32 | 2 | 1 |
| Nathan Eovaldi | Oak | sp | 34 | 3.69 | 5 | 9 | 0 | 22 | 22 | 0 | 0 | 134.0 | 119 | 56 | 55 | 32 | 133 | 17 | 6 |
| Lucas Erceg | LAN | mr | 29 | 3.96 | 2 | 2 | 2 | 23 | 0 | 0 | 0 | 25.0 | 18 | 13 | 11 | 22 | 25 | 5 | 3 |
| Joey Estes | Mia | sp | 22 | 5.82 | 2 | 1 | 1 | 13 | 4 | 0 | 0 | 38.2 | 49 | 27 | 25 | 12 | 29 | 11 | 2 |
| Carlos Estevez | Tor | mr | 31 | 5.87 | 5 | 4 | 15 | 56 | 0 | 0 | 0 | 61.1 | 59 | 46 | 40 | 33 | 73 | 9 | 2 |
| Jeremiah Estrada | Sea | mr | 25 | 5.18 | 2 | 1 | 5 | 43 | 0 | 0 | 0 | 57.1 | 56 | 39 | 33 | 38 | 71 | 8 | 3 |
| Alex Faedo | Phi | sp | 28 | 5.53 | 5 | 12 | 0 | 30 | 23 | 1 | 0 | 148.0 | 160 | 95 | 91 | 45 | 135 | 22 | 4 |
| Pete Fairbanks | ChN | cl | 30 | 4.08 | 2 | 1 | 1 | 28 | 0 | 0 | 0 | 28.2 | 27 | 14 | 13 | 12 | 48 | 3 | 1 |
| Bailey Falter* | KC | sp | 27 | 4.78 | 1 | 6 | 0 | 9 | 9 | 0 | 0 | 49.0 | 52 | 28 | 26 | 11 | 45 | 5 | 1 |
| Calvin Faucher | Hou | mr | 28 | 7.79 | 1 | 0 | 1 | 16 | 0 | 0 | 0 | 17.1 | 24 | 15 | 15 | 12 | 14 | 5 | 1 |
| Erick Fedde | Hou | sp | 31 | 9.76 | 2 | 4 | 0 | 16 | 5 | 0 | 0 | 43.1 | 69 | 49 | 47 | 14 | 43 | 13 | 3 |
| Caleb Ferguson* | Tor | mr | 27 | 5.73 | 1 | 2 | 2 | 36 | 0 | 0 | 0 | 37.2 | 46 | 25 | 24 | 12 | 47 | 7 | 2 |
| Ryan Fernandez | SD | mr | 26 | 5.83 | 2 | 1 | 6 | 37 | 0 | 0 | 0 | 54.0 | 47 | 36 | 35 | 18 | 53 | 13 | 0 |
| Jose A. Ferrer* | Mia | mr | 24 | 3.72 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 9.2 | 11 | 4 | 4 | 4 | 10 | 1 | 0 |
| David Festa | | sp | 24 | 4.80 | 5 | 8 | 2 | 38 | 20 | 0 | 0 | 120.0 | 111 | 71 | 64 | 48 | 113 | 13 | 7 |
| J.P. Feyereisen | Pit | mr | 31 | 3.96 | 2 | 1 | 2 | 32 | 1 | 0 | 0 | 38.2 | 46 | 19 | 17 | 16 | 43 | 8 | 1 |
| Kyle Finnegan | NYN | cl | 32 | 4.00 | 2 | 3 | 4 | 46 | 0 | 0 | 0 | 63.0 | 48 | 31 | 28 | 17 | 62 | 15 | 5 |
| Richard Fitts | | sp | 24 | 3.75 | 4 | 6 | 0 | 20 | 20 | 2 | 1 | 132.0 | 120 | 59 | 55 | 26 | 97 | 12 | 6 |
| Jack Flaherty | Hou | sp | 28 | 3.25 | 13 | 10 | 0 | 34 | 33 | 1 | 1 | 207.2 | 161 | 88 | 75 | 80 | 185 | 20 | 20 |
| Josh Fleming* | Tam | mr | 28 | 3.12 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 8.2 | 10 | 4 | 3 | 1 | 4 | 0 | 3 |
| Wilmer Flores | ChN | sp | 23 | 0.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.0 | 2 | 1 | 0 | 1 | 5 | 0 | 0 |
| Dylan Floro | Was | mr | 33 | 2.60 | 5 | 2 | 3 | 25 | 0 | 0 | 0 | 34.2 | 38 | 16 | 10 | 5 | 36 | 2 | 3 |
| Mason Fluharty* | Phi | mr | 22 | 5.87 | 5 | 6 | 0 | 75 | 2 | 0 | 0 | 110.1 | 121 | 77 | 72 | 50 | 111 | 17 | 8 |
| Jason Foley | Oak | mr | 28 | 4.70 | 1 | 4 | 7 | 35 | 0 | 0 | 0 | 46.0 | 53 | 26 | 24 | 12 | 31 | 8 | 4 |
| J.P. France | KC | sp | 29 | 5.40 | 2 | 2 | 0 | 35 | 0 | 0 | 0 | 45.0 | 52 | 31 | 27 | 20 | 49 | 5 | 6 |
| Bowden Francis | Tex | sp | 28 | 3.03 | 2 | 3 | 0 | 8 | 7 | 0 | 0 | 38.2 | 28 | 13 | 13 | 9 | 36 | 6 | 4 |
| Kyle Freeland* | Min | sp | 31 | 1.80 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 5.0 | 5 | 1 | 1 | 1 | 3 | 0 | 1 |
| Luis Frias | Bal | mr | 26 | 5.63 | 7 | 7 | 1 | 24 | 20 | 0 | 0 | 112.0 | 129 | 76 | 70 | 61 | 112 | 14 | 5 |
| Max Fried* | Ari | sp | 30 | 2.45 | 16 | 7 | 0 | 32 | 32 | 2 | 1 | 220.1 | 176 | 68 | 60 | 39 | 220 | 12 | 14 |
| Kody Funderburk* | ChN | mr | 27 | 4.17 | 2 | 4 | 0 | 11 | 11 | 0 | 0 | 58.1 | 54 | 29 | 27 | 23 | 62 | 8 | 5 |
| Hunter Gaddis | Bos | sp | 26 | 4.25 | 15 | 8 | 1 | 41 | 24 | 0 | 0 | 165.0 | 148 | 81 | 78 | 53 | 153 | 21 | 9 |
| Giovanny Gallegos | | mr | 32 | 4.53 | 3 | 1 | 1 | 36 | 0 | 0 | 0 | 43.2 | 32 | 25 | 22 | 10 | 50 | 7 | 3 |
| Zac Gallen | | sp | 28 | 2.75 | 10 | 9 | 0 | 29 | 29 | 6 | 3 | 212.2 | 152 | 68 | 65 | 56 | 183 | 18 | 9 |
| Robert Garcia* | Was | mr | 28 | 4.08 | 5 | 2 | 0 | 18 | 0 | 0 | 0 | 35.1 | 31 | 18 | 16 | 15 | 33 | 5 | 4 |
| Yimi Garcia | | mr | 33 | 3.26 | 2 | 4 | 3 | 39 | 0 | 0 | 0 | 47.0 | 42 | 18 | 17 | 16 | 56 | 5 | 3 |
| Braxton Garrett* | Mia | sp | 26 | 4.17 | 4 | 2 | 0 | 9 | 9 | 0 | 0 | 58.1 | 66 | 27 | 27 | 8 | 34 | 9 | 3 |
| Reed Garrett | NYN | mr | 31 | 6.75 | 0 | 1 | 2 | 8 | 0 | 0 | 0 | 10.2 | 16 | 10 | 8 | 4 | 10 | 2 | 1 |
| Robert Gasser* | Atl | sp | 25 | 7.57 | 2 | 5 | 0 | 7 | 7 | 0 | 0 | 35.2 | 43 | 32 | 30 | 11 | 39 | 7 | 0 |
| Chris Gau | Oak | mr | 27 | 3.08 | 7 | 2 | 0 | 21 | 15 | 0 | 0 | 96.1 | 80 | 35 | 33 | 29 | 88 | 8 | 4 |
| Kevin Gausman | | sp | 33 | 3.74 | 14 | 10 | 0 | 37 | 37 | 1 | 0 | 245.2 | 220 | 106 | 102 | 51 | 270 | 37 | 9 |
| Domingo German | Pit | sp | 31 | 3.71 | 9 | 13 | 0 | 33 | 33 | 1 | 0 | 206.1 | 206 | 103 | 85 | 50 | 195 | 29 | 12 |
| Kyle Gibson | Min | sp | 36 | 4.58 | 11 | 9 | 0 | 29 | 29 | 1 | 0 | 182.2 | 189 | 98 | 93 | 62 | 122 | 17 | 19 |
| Luis Gil | | sp | 26 | 4.52 | 4 | 13 | 0 | 30 | 24 | 0 | 0 | 127.1 | 103 | 67 | 64 | 73 | 151 | 17 | 4 |
| Logan Gilbert | Ari | sp | 27 | 3.41 | 17 | 9 | 0 | 34 | 34 | 4 | 2 | 248.0 | 219 | 102 | 94 | 63 | 241 | 21 | 15 |
| Keagan Gillies | Cin | mr | 26 | 9.00 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 4.0 | 6 | 4 | 4 | 0 | 4 | 2 | 0 |
| Kevin Ginkel | | mr | 30 | 2.95 | 4 | 0 | 4 | 49 | 0 | 0 | 0 | 73.1 | 48 | 26 | 24 | 32 | 83 | 8 | 5 |
| J.T. Ginn | Pit | sp | 25 | 5.17 | 0 | 2 | 0 | 3 | 3 | 0 | 0 | 15.2 | 18 | 9 | 9 | 5 | 16 | 3 | 5 |
| Tyler Glasnow | Sea | sp | 30 | 3.62 | 7 | 9 | 0 | 23 | 23 | 0 | 0 | 126.2 | 100 | 54 | 51 | 32 | 156 | 19 | 1 |
| Woo-suk Go | Mil | mr | 25 | 5.13 | 2 | 2 | 1 | 35 | 0 | 0 | 0 | 40.1 | 34 | 23 | 23 | 15 | 43 | 9 | 4 |
| Yoendrys Gomez | NYA | sp | 24 | 7.91 | 0 | 3 | 2 | 22 | 0 | 0 | 0 | 19.1 | 26 | 18 | 17 | 7 | 18 | 6 | 2 |
| Marco Gonzales* | ChA | sp | 32 | 5.54 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 13.0 | 21 | 8 | 8 | 4 | 8 | 2 | 1 |
| Colton Gordon* | Phi | sp | 25 | 3.97 | 2 | 3 | 4 | 31 | 3 | 0 | 0 | 47.2 | 45 | 22 | 21 | 15 | 32 | 3 | 5 |
| MacKenzie Gore* | NYN | sp | 25 | 3.26 | 13 | 14 | 0 | 33 | 33 | 2 | 2 | 218.1 | 155 | 88 | 79 | 75 | 243 | 26 | 18 |
| Anthony Gose* | Hou | mr | 33 | 3.92 | 5 | 2 | 3 | 60 | 0 | 0 | 0 | 62.0 | 39 | 29 | 27 | 36 | 79 | 11 | 3 |
| Gordon Graceffo | | sp | 24 | 3.90 | 6 | 6 | 1 | 44 | 6 | 0 | 0 | 80.2 | 90 | 41 | 35 | 29 | 54 | 8 | 3 |
| Brusdar Graterol | Bal | mr | 25 | 1.86 | 2 | 0 | 5 | 15 | 0 | 0 | 0 | 19.1 | 15 | 6 | 4 | 3 | 19 | 2 | 2 |
| Jon Gray | Oak | sp | 32 | 3.79 | 12 | 9 | 0 | 27 | 27 | 1 | 1 | 171.0 | 140 | 75 | 72 | 45 | 167 | 25 | 10 |
| Sonny Gray | | sp | 34 | 4.32 | 8 | 9 | 0 | 26 | 26 | 2 | 1 | 160.1 | 163 | 86 | 77 | 41 | 136 | 19 | 9 |
| Chad Green | ChN | mr | 33 | 3.05 | 2 | 4 | 5 | 49 | 0 | 0 | 0 | 59.0 | 41 | 23 | 20 | 13 | 71 | 4 | 2 |
| Hunter Greene | Col | sp | 24 | 5.25 | 3 | 7 | 0 | 25 | 23 | 1 | 0 | 135.1 | 136 | 88 | 79 | 55 | 193 | 18 | 2 |
| Michael Grove | | sp | 27 | 2.58 | 4 | 1 | 4 | 31 | 5 | 0 | 0 | 52.1 | 44 | 17 | 15 | 14 | 56 | 4 | 5 |
| Luis Guerrero | Tor | mr | 23 | 5.57 | 0 | 0 | 2 | 16 | 0 | 0 | 0 | 21.0 | 24 | 14 | 13 | 9 | 20 | 0 | 2 |
| Tyson Guerrero* | Sea | sp | 25 | 1.29 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 7.0 | 3 | 1 | 1 | 0 | 9 | 1 | 1 |
| Josh Hader* | | cl | 30 | 2.09 | 5 | 4 | 24 | 64 | 0 | 0 | 0 | 60.1 | 38 | 17 | 14 | 18 | 87 | 2 | 6 |
| Justin Hagenman | Oak | mr | 27 | 4.94 | 4 | 7 | 0 | 14 | 14 | 0 | 0 | 71.0 | 78 | 44 | 39 | 27 | 51 | 9 | 4 |
| DL Hall* | Bal | mr | 25 | 4.07 | 8 | 5 | 1 | 43 | 20 | 0 | 0 | 115.0 | 97 | 54 | 52 | 60 | 158 | 17 | 5 |
| Ian Hamilton | Tex | mr | 29 | 1.56 | 5 | 1 | 3 | 45 | 2 | 0 | 0 | 69.1 | 43 | 18 | 12 | 17 | 88 | 7 | 3 |
| Emerson Hancock | Sea | sp | 25 | 4.09 | 5 | 16 | 0 | 31 | 31 | 1 | 1 | 176.0 | 193 | 90 | 80 | 43 | 161 | 15 | 13 |
| Hayden Harris* | | mr | 25 | 4.89 | 2 | 0 | 3 | 30 | 0 | 0 | 0 | 35.0 | 36 | 23 | 19 | 16 | 33 | 1 | 3 |
| Kyle Harrison* | Atl | sp | 22 | 4.07 | 9 | 7 | 0 | 27 | 27 | 0 | 0 | 130.1 | 122 | 66 | 59 | 76 | 144 | 19 | 8 |
| Grant Hartwig | NYN | mr | 26 | 4.70 | 1 | 0 | 4 | 16 | 0 | 0 | 0 | 15.1 | 14 | 8 | 8 | 12 | 13 | 1 | 1 |
| Hunter Harvey | | mr | 29 | 2.62 | 10 | 4 | 11 | 49 | 0 | 0 | 0 | 55.0 | 40 | 18 | 16 | 10 | 46 | 3 | 5 |
| Andrew Heaney* | KC | sp | 33 | 4.28 | 7 | 6 | 0 | 18 | 16 | 0 | 0 | 96.2 | 99 | 50 | 46 | 24 | 107 | 18 | 10 |
| Ryan Helsley | | cl | 29 | 3.19 | 9 | 5 | 25 | 61 | 0 | 0 | 0 | 67.2 | 58 | 32 | 24 | 17 | 87 | 9 | 3 |
| Markevian Hence | SF | sp | 21 | 4.57 | 5 | 12 | 2 | 65 | 17 | 0 | 0 | 163.1 | 171 | 101 | 83 | 51 | 118 | 24 | 14 |
| Ryan Hennen* | Det | mr | 26 | 3.17 | 1 | 2 | 3 | 34 | 0 | 0 | 0 | 54.0 | 46 | 21 | 19 | 9 | 44 | 6 | 3 |
| Ronny Henriquez | Was | mr | 24 | 4.28 | 2 | 2 | 2 | 19 | 6 | 1 | 0 | 73.2 | 79 | 36 | 35 | 23 | 52 | 9 | 4 |
| Cole Henry | Pit | sp | 24 | 4.01 | 5 | 5 | 0 | 26 | 18 | 0 | 0 | 103.1 | 101 | 49 | 46 | 33 | 106 | 13 | 7 |
| Tommy Henry* | LAA | sp | 26 | 2.87 | 2 | 3 | 3 | 40 | 6 | 0 | 0 | 81.2 | 73 | 33 | 26 | 21 | 65 | 7 | 2 |
| Sam Hentges* | Tex | mr | 27 | 5.15 | 1 | 2 | 10 | 29 | 0 | 0 | 0 | 36.2 | 30 | 21 | 21 | 8 | 36 | 8 | 3 |
| Carlos Hernandez | Tex | mr | 27 | 4.91 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3.2 | 3 | 2 | 2 | 0 | 0 | 1 | 1 |
| Daysbel Hernandez | NYN | mr | 27 | 6.75 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 1.1 | 3 | 1 | 1 | 2 | 2 | 0 | 0 |
| Jakob Hernandez* | Oak | mr | 28 | 5.40 | 0 | 1 | 1 | 6 | 0 | 0 | 0 | 5.0 | 7 | 4 | 3 | 2 | 6 | 1 | 1 |
| Jose Hernandez* | Was | mr | 26 | 3.24 | 0 | 1 | 1 | 20 | 1 | 0 | 0 | 25.0 | 21 | 9 | 9 | 12 | 32 | 1 | 2 |
| Tim Herrin* | Sea | mr | 27 | 3.67 | 5 | 2 | 2 | 51 | 0 | 0 | 0 | 83.1 | 62 | 36 | 34 | 30 | 87 | 11 | 7 |
| Jordan Hicks | SF | mr | 27 | 5.73 | 4 | 6 | 9 | 99 | 1 | 0 | 0 | 99.0 | 106 | 66 | 63 | 62 | 119 | 14 | 10 |
| Porter Hodge | Was | mr | 23 | 4.67 | 3 | 5 | 2 | 19 | 12 | 0 | 0 | 81.0 | 71 | 44 | 42 | 40 | 72 | 11 | 5 |
| Jeff Hoffman | | mr | 31 | 5.14 | 4 | 9 | 12 | 59 | 1 | 0 | 0 | 70.0 | 79 | 45 | 40 | 29 | 96 | 10 | 1 |
| Gunnar Hoglund | Oak | sp | 24 | 4.61 | 2 | 2 | 0 | 5 | 5 | 0 | 0 | 27.1 | 31 | 15 | 14 | 7 | 22 | 3 | 3 |
| Colin Holderman | Phi | mr | 28 | 3.60 | 5 | 5 | 12 | 73 | 0 | 0 | 0 | 90.0 | 74 | 45 | 36 | 29 | 98 | 13 | 5 |
| Grant Holman | KC | mr | 24 | 4.19 | 2 | 3 | 5 | 65 | 0 | 0 | 0 | 53.2 | 63 | 28 | 25 | 17 | 54 | 7 | 7 |
| Clay Holmes | Oak | cl | 31 | 2.51 | 7 | 3 | 2 | 62 | 0 | 0 | 0 | 71.2 | 55 | 23 | 20 | 19 | 89 | 9 | 4 |
| Grant Holmes | Mia | mr | 28 | 2.66 | 2 | 2 | 4 | 31 | 2 | 0 | 0 | 47.1 | 36 | 17 | 14 | 15 | 52 | 6 | 3 |
| Tyler Holton* | | mr | 28 | 3.65 | 8 | 3 | 13 | 66 | 3 | 0 | 0 | 93.2 | 76 | 39 | 38 | 17 | 80 | 8 | 6 |
| Brent Honeywell | Col | mr | 29 | 3.52 | 2 | 1 | 0 | 13 | 5 | 0 | 0 | 46.0 | 42 | 19 | 18 | 14 | 29 | 4 | 2 |
| Tanner Houck | LAN | sp | 28 | 4.77 | 7 | 13 | 0 | 33 | 33 | 0 | 0 | 188.2 | 179 | 109 | 100 | 67 | 193 | 31 | 17 |
| Spencer Howard | | sp | 27 | 4.41 | 0 | 0 | 0 | 21 | 2 | 0 | 0 | 32.2 | 35 | 16 | 16 | 14 | 38 | 8 | 2 |
| Bryan Hudson* | Col | mr | 27 | 6.80 | 1 | 6 | 2 | 45 | 0 | 0 | 0 | 47.2 | 64 | 40 | 36 | 20 | 58 | 9 | 1 |
| Daniel Hudson | | mr | 37 | 3.61 | 4 | 3 | 1 | 25 | 5 | 0 | 0 | 47.1 | 42 | 20 | 19 | 16 | 50 | 10 | 4 |
| Brandon Hughes* | NYN | mr | 28 | 2.14 | 1 | 0 | 1 | 16 | 0 | 0 | 0 | 21.0 | 9 | 5 | 5 | 6 | 17 | 2 | 2 |
| Kyle Hurt | Bos | sp | 26 | 4.50 | 2 | 1 | 0 | 8 | 6 | 0 | 0 | 38.0 | 31 | 19 | 19 | 14 | 46 | 8 | 1 |
| Brant Hurter* | ChN | sp | 25 | 4.01 | 13 | 8 | 0 | 33 | 33 | 0 | 0 | 197.2 | 197 | 99 | 88 | 45 | 148 | 24 | 15 |
| Raisel Iglesias | | cl | 34 | 2.79 | 4 | 7 | 25 | 60 | 0 | 0 | 0 | 71.0 | 66 | 29 | 22 | 11 | 87 | 4 | 4 |
| Shota Imanaga* | SD | sp | 30 | 3.31 | 8 | 10 | 0 | 33 | 33 | 0 | 0 | 174.0 | 153 | 70 | 64 | 37 | 177 | 23 | 10 |
| Jairo Iriarte | Col | sp | 22 | 9.45 | 3 | 4 | 0 | 26 | 3 | 0 | 0 | 40.0 | 58 | 50 | 42 | 18 | 42 | 10 | 3 |
| Cole Irvin* | ChA | sp | 30 | 5.06 | 5 | 18 | 0 | 33 | 32 | 5 | 0 | 197.1 | 233 | 121 | 111 | 30 | 145 | 34 | 17 |
| Jake Irvin | | sp | 27 | 3.88 | 6 | 7 | 0 | 21 | 21 | 0 | 0 | 120.2 | 103 | 59 | 52 | 43 | 96 | 21 | 15 |
| Jay Jackson | Mia | mr | 36 | 4.91 | 3 | 7 | 9 | 48 | 0 | 0 | 0 | 51.1 | 54 | 31 | 28 | 19 | 61 | 12 | 0 |
| Alek Jacob | Pit | mr | 26 | 2.21 | 1 | 0 | 0 | 11 | 0 | 0 | 0 | 20.1 | 13 | 7 | 5 | 3 | 15 | 2 | 1 |
| Kenley Jansen | | cl | 36 | 6.21 | 8 | 9 | 11 | 52 | 0 | 0 | 0 | 58.0 | 67 | 48 | 40 | 26 | 73 | 15 | 2 |
| Bryce Jarvis | LAA | sp | 26 | 4.15 | 3 | 3 | 2 | 30 | 5 | 0 | 0 | 65.0 | 53 | 36 | 30 | 19 | 45 | 13 | 3 |
| Cristian Javier | Min | sp | 27 | 3.50 | 2 | 3 | 0 | 6 | 6 | 0 | 0 | 36.0 | 31 | 14 | 14 | 13 | 42 | 5 | 0 |
| Griffin Jax | Min | mr | 29 | 3.00 | 1 | 4 | 10 | 34 | 3 | 0 | 0 | 54.0 | 48 | 21 | 18 | 12 | 51 | 3 | 4 |
| Joe Jimenez | NYN | mr | 29 | 4.48 | 4 | 6 | 1 | 64 | 0 | 0 | 0 | 68.1 | 52 | 34 | 34 | 25 | 85 | 12 | 1 |
| Jackson Jobe | SF | sp | 21 | 5.07 | 2 | 8 | 0 | 43 | 15 | 0 | 0 | 119.0 | 131 | 75 | 67 | 45 | 98 | 18 | 8 |
| Pierce Johnson | Mil | mr | 33 | 5.13 | 0 | 1 | 4 | 31 | 0 | 0 | 0 | 33.1 | 26 | 20 | 19 | 14 | 42 | 6 | 1 |
| Seth Johnson | Phi | sp | 25 | 4.62 | 4 | 6 | 0 | 27 | 14 | 0 | 0 | 87.2 | 81 | 50 | 45 | 38 | 91 | 12 | 5 |
| Jared Jones | Bos | sp | 22 | 4.15 | 6 | 8 | 0 | 22 | 22 | 0 | 0 | 136.2 | 118 | 69 | 63 | 55 | 120 | 13 | 11 |
| Hayden Juenger | Hou | mr | 23 | 3.75 | 3 | 2 | 1 | 36 | 6 | 0 | 0 | 69.2 | 58 | 31 | 29 | 31 | 63 | 6 | 7 |
| Jakob Junis | Det | mr | 31 | 3.13 | 0 | 3 | 2 | 9 | 2 | 0 | 0 | 23.0 | 23 | 15 | 8 | 2 | 15 | 4 | 4 |
| Tommy Kahnle | Oak | mr | 34 | 3.12 | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 17.1 | 16 | 8 | 6 | 4 | 24 | 3 | 2 |
| Mitch Keller | | sp | 28 | 3.83 | 12 | 13 | 0 | 34 | 34 | 4 | 1 | 218.1 | 204 | 101 | 93 | 59 | 200 | 22 | 21 |
| Antoine Kelly* | Atl | mr | 24 | 6.75 | 0 | 2 | 3 | 13 | 0 | 0 | 0 | 13.1 | 16 | 12 | 10 | 7 | 15 | 1 | 2 |
| Joe Kelly | LAA | mr | 36 | 3.86 | 0 | 1 | 1 | 20 | 0 | 0 | 0 | 18.2 | 18 | 8 | 8 | 9 | 21 | 2 | 2 |
| Kevin Kelly | | mr | 26 | 3.27 | 6 | 6 | 11 | 62 | 0 | 0 | 0 | 74.1 | 70 | 31 | 27 | 17 | 78 | 2 | 4 |
| Merrill Kelly | Det | sp | 35 | 2.46 | 10 | 3 | 0 | 15 | 15 | 2 | 2 | 109.2 | 90 | 31 | 30 | 20 | 101 | 10 | 2 |
| Michael Kelly | Bal | mr | 31 | 4.46 | 4 | 3 | 2 | 28 | 0 | 0 | 0 | 36.1 | 36 | 24 | 18 | 27 | 37 | 4 | 7 |
| Zack Kelly | Bal | mr | 29 | 6.27 | 1 | 1 | 1 | 22 | 0 | 0 | 0 | 33.0 | 29 | 24 | 23 | 25 | 32 | 7 | 2 |
| Orion Kerkering | Bos | mr | 23 | 3.65 | 7 | 2 | 10 | 61 | 0 | 0 | 0 | 81.1 | 79 | 37 | 33 | 16 | 98 | 12 | 2 |
| Ray Kerr* | LAA | mr | 29 | 1.29 | 1 | 0 | 0 | 8 | 0 | 0 | 0 | 7.0 | 6 | 2 | 1 | 4 | 11 | 0 | 0 |
| Brett Kerry | NYA | sp | 25 | 6.93 | 2 | 7 | 1 | 24 | 13 | 0 | 0 | 85.2 | 112 | 71 | 66 | 31 | 58 | 20 | 8 |
| Clayton Kershaw* | LAA | sp | 36 | 2.41 | 3 | 1 | 0 | 6 | 6 | 0 | 0 | 41.0 | 36 | 14 | 11 | 5 | 53 | 5 | 1 |
| Yusei Kikuchi* | NYN | sp | 33 | 2.89 | 10 | 7 | 0 | 32 | 32 | 2 | 1 | 208.2 | 171 | 73 | 67 | 45 | 216 | 38 | 17 |
| Craig Kimbrel | | cl | 36 | 6.29 | 5 | 4 | 9 | 47 | 0 | 0 | 0 | 48.2 | 51 | 38 | 34 | 24 | 51 | 11 | 1 |
| John King* | StL | mr | 29 | 3.16 | 3 | 2 | 7 | 48 | 0 | 0 | 0 | 62.2 | 58 | 24 | 22 | 15 | 34 | 5 | 4 |
| Michael King | Tam | mr | 29 | 4.15 | 11 | 11 | 0 | 32 | 32 | 0 | 0 | 180.0 | 157 | 92 | 83 | 65 | 225 | 32 | 12 |
| George Kirby | Sea | sp | 26 | 4.28 | 10 | 12 | 0 | 32 | 32 | 0 | 0 | 202.0 | 224 | 106 | 96 | 24 | 176 | 26 | 15 |
| Andrew Kittredge | ChN | mr | 34 | 5.09 | 2 | 0 | 2 | 12 | 0 | 0 | 0 | 17.2 | 18 | 10 | 10 | 3 | 9 | 3 | 2 |
| Will Klein | Mia | mr | 24 | 1.50 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 12.0 | 9 | 3 | 2 | 6 | 9 | 1 | 2 |
| Jared Koenig* | Tam | mr | 30 | 4.97 | 0 | 2 | 0 | 9 | 0 | 0 | 0 | 12.2 | 11 | 7 | 7 | 3 | 10 | 4 | 2 |
| Michael Kopech | SF | sp | 28 | 6.75 | 2 | 7 | 1 | 20 | 14 | 0 | 0 | 84.0 | 97 | 70 | 63 | 53 | 79 | 17 | 2 |
| Dean Kremer | Det | sp | 28 | 3.23 | 11 | 13 | 0 | 34 | 34 | 2 | 2 | 228.1 | 190 | 85 | 82 | 51 | 204 | 29 | 15 |
| Alex Lange | LAN | cl | 28 | 2.80 | 5 | 8 | 23 | 48 | 0 | 0 | 0 | 61.0 | 48 | 30 | 19 | 22 | 78 | 3 | 3 |
| Jake Latz* | Phi | mr | 28 | 7.27 | 0 | 1 | 0 | 9 | 0 | 0 | 0 | 8.2 | 10 | 7 | 7 | 1 | 12 | 3 | 0 |
| Nate Lavender* | ChA | mr | 24 | 3.58 | 9 | 5 | 2 | 59 | 0 | 0 | 0 | 75.1 | 64 | 31 | 30 | 31 | 96 | 7 | 5 |
| Justin Lawrence | Bos | mr | 29 | 2.20 | 3 | 6 | 22 | 53 | 0 | 0 | 0 | 65.1 | 45 | 24 | 16 | 35 | 65 | 3 | 6 |
| Max Lazar | NYA | mr | 25 | 4.31 | 4 | 4 | 2 | 75 | 0 | 0 | 0 | 110.2 | 124 | 59 | 53 | 25 | 77 | 17 | 5 |
| Jose Leclerc | Pit | mr | 30 | 4.55 | 4 | 1 | 2 | 55 | 0 | 0 | 0 | 65.1 | 57 | 35 | 33 | 36 | 69 | 10 | 4 |
| Dylan Lee* | | mr | 29 | 2.51 | 7 | 2 | 6 | 63 | 0 | 0 | 0 | 71.2 | 61 | 23 | 20 | 15 | 77 | 6 | 2 |
| Jack Leiter | SF | sp | 24 | 6.83 | 2 | 10 | 3 | 38 | 13 | 0 | 0 | 108.0 | 118 | 89 | 82 | 58 | 114 | 20 | 7 |
| Mark Leiter | Bos | mr | 33 | 2.23 | 7 | 3 | 6 | 50 | 2 | 0 | 0 | 80.2 | 49 | 24 | 20 | 25 | 84 | 7 | 4 |
| Matthew Liberatore* | | sp | 24 | 3.55 | 4 | 6 | 1 | 22 | 18 | 1 | 0 | 121.2 | 118 | 50 | 48 | 36 | 111 | 12 | 7 |
| Yu-Min Lin* | Bal | sp | 20 | 3.85 | 8 | 7 | 3 | 55 | 29 | 0 | 0 | 196.1 | 167 | 90 | 84 | 72 | 202 | 18 | 14 |
| Zack Littell | Cle | mr | 28 | 3.55 | 11 | 10 | 0 | 32 | 23 | 0 | 0 | 154.2 | 152 | 64 | 61 | 31 | 136 | 18 | 6 |
| Brendon Little* | LAN | mr | 27 | 3.97 | 7 | 8 | 4 | 62 | 0 | 0 | 0 | 79.1 | 81 | 46 | 35 | 34 | 61 | 10 | 4 |
| Luke Little* | Hou | mr | 23 | 5.40 | 1 | 2 | 1 | 29 | 0 | 0 | 0 | 28.1 | 28 | 18 | 17 | 17 | 42 | 3 | 1 |
| Ben Lively | | sp | 32 | 3.80 | 8 | 9 | 0 | 23 | 23 | 0 | 0 | 144.1 | 138 | 68 | 61 | 39 | 126 | 17 | 7 |
| Mauricio Llovera | StL | mr | 28 | 5.08 | 1 | 3 | 3 | 16 | 6 | 0 | 0 | 39.0 | 43 | 25 | 22 | 6 | 34 | 6 | 1 |
| Jonathan Loaisiga | Ari | mr | 29 | 3.38 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 10.2 | 10 | 4 | 4 | 1 | 12 | 2 | 0 |
| Nick Lodolo* | | sp | 26 | 3.40 | 5 | 4 | 0 | 9 | 9 | 0 | 0 | 55.2 | 48 | 24 | 21 | 13 | 64 | 7 | 3 |
| Pablo Lopez | Tex | sp | 28 | 3.69 | 19 | 12 | 0 | 35 | 34 | 2 | 0 | 239.1 | 202 | 109 | 98 | 60 | 259 | 24 | 10 |
| Reynaldo Lopez | LAA | mr | 30 | 3.32 | 3 | 1 | 2 | 32 | 1 | 0 | 0 | 43.1 | 34 | 17 | 16 | 15 | 57 | 5 | 2 |
| Michael Lorenzen | LAA | sp | 32 | 2.84 | 4 | 6 | 1 | 25 | 12 | 0 | 0 | 92.0 | 74 | 32 | 29 | 29 | 64 | 9 | 17 |
| Ryan Loutos | Mia | mr | 25 | 18.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.0 | 3 | 2 | 2 | 1 | 1 | 1 | 0 |
| Richard Lovelady* | | mr | 28 | 3.10 | 2 | 2 | 2 | 29 | 0 | 0 | 0 | 29.0 | 24 | 11 | 10 | 10 | 22 | 3 | 3 |
| Seth Lugo | NYN | sp | 34 | 3.60 | 14 | 11 | 0 | 32 | 32 | 3 | 1 | 215.0 | 177 | 92 | 86 | 46 | 171 | 27 | 7 |
| Jesus Luzardo* | Cle | sp | 26 | 3.12 | 6 | 2 | 0 | 15 | 15 | 0 | 0 | 92.1 | 85 | 38 | 32 | 28 | 109 | 8 | 8 |
| Daniel Lynch* | Phi | sp | 27 | 3.38 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.1 | 4 | 2 | 2 | 3 | 5 | 0 | 0 |
| Lance Lynn | LAN | sp | 37 | 4.15 | 10 | 17 | 0 | 32 | 32 | 2 | 1 | 204.0 | 181 | 111 | 94 | 47 | 183 | 24 | 10 |
| Adam Macko* | | sp | 23 | 6.82 | 3 | 6 | 0 | 30 | 5 | 0 | 0 | 63.1 | 69 | 53 | 48 | 34 | 64 | 11 | 4 |
| Kenta Maeda | Mil | sp | 36 | 1.38 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 13.0 | 9 | 6 | 2 | 3 | 10 | 0 | 1 |
| Tyler Mahle | Ari | sp | 29 | 0.64 | 2 | 0 | 0 | 2 | 2 | 0 | 0 | 14.0 | 6 | 1 | 1 | 5 | 13 | 0 | 0 |
| Anthony Maldonado | Tor | mr | 26 | 5.03 | 2 | 5 | 5 | 74 | 0 | 0 | 0 | 91.1 | 91 | 57 | 51 | 35 | 106 | 10 | 7 |
| Matt Manning | Mia | sp | 26 | 3.00 | 9 | 2 | 0 | 18 | 14 | 1 | 1 | 96.0 | 71 | 33 | 32 | 25 | 73 | 9 | 2 |
| Alek Manoah | Sea | sp | 26 | 6.23 | 0 | 2 | 0 | 4 | 4 | 0 | 0 | 21.2 | 23 | 15 | 15 | 7 | 26 | 2 | 0 |
| Joe Mantiply* | KC | mr | 33 | 3.26 | 3 | 2 | 2 | 59 | 0 | 0 | 0 | 58.0 | 47 | 23 | 21 | 12 | 55 | 4 | 10 |
| Ron Marinaccio | ChA | mr | 28 | 6.28 | 3 | 3 | 6 | 80 | 0 | 0 | 0 | 76.0 | 80 | 54 | 53 | 43 | 79 | 13 | 3 |
| German Marquez | Bos | sp | 29 | 0.53 | 2 | 0 | 0 | 2 | 2 | 1 | 1 | 17.0 | 7 | 1 | 1 | 4 | 15 | 0 | 1 |
| Alec Marsh | | sp | 26 | 4.70 | 3 | 5 | 3 | 41 | 9 | 0 | 0 | 97.2 | 106 | 57 | 51 | 35 | 98 | 10 | 6 |
| Chris Martin | ChN | mr | 38 | 1.91 | 2 | 0 | 3 | 24 | 0 | 0 | 0 | 33.0 | 26 | 7 | 7 | 3 | 27 | 2 | 1 |
| Davis Martin | SD | sp | 27 | 5.40 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 5.0 | 5 | 3 | 3 | 3 | 5 | 2 | 0 |
| Justin Martinez | Tex | mr | 22 | 5.46 | 5 | 1 | 3 | 54 | 0 | 0 | 0 | 56.0 | 44 | 39 | 34 | 44 | 72 | 8 | 4 |
| Nick Martinez | Mil | mr | 33 | 3.51 | 13 | 11 | 0 | 32 | 32 | 1 | 1 | 205.1 | 190 | 87 | 80 | 56 | 203 | 21 | 15 |
| Seth Martinez | Hou | mr | 29 | 4.47 | 7 | 7 | 5 | 85 | 0 | 0 | 0 | 108.2 | 117 | 58 | 54 | 35 | 102 | 14 | 8 |
| Phil Maton | | mr | 31 | 4.02 | 3 | 5 | 6 | 58 | 0 | 0 | 0 | 69.1 | 60 | 32 | 31 | 27 | 83 | 11 | 7 |
| Yuki Matsui* | NYN | mr | 28 | 1.20 | 4 | 2 | 11 | 46 | 0 | 0 | 0 | 52.2 | 33 | 10 | 7 | 29 | 73 | 2 | 3 |
| Steven Matz* | | sp | 33 | 2.62 | 5 | 1 | 1 | 15 | 6 | 0 | 0 | 44.2 | 36 | 16 | 13 | 16 | 41 | 2 | 4 |
| Tyler Matzek* | SD | mr | 33 | 4.41 | 0 | 0 | 1 | 17 | 0 | 0 | 0 | 16.1 | 11 | 8 | 8 | 7 | 22 | 3 | 0 |
| Tim Mayza* | | mr | 32 | 4.12 | 1 | 1 | 0 | 20 | 0 | 0 | 0 | 19.2 | 22 | 9 | 9 | 4 | 16 | 1 | 2 |
| James McArthur | Det | mr | 27 | 9.72 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 8.1 | 13 | 9 | 9 | 0 | 6 | 1 | 2 |
| Chayce McDermott | LAN | sp | 25 | 3.32 | 6 | 7 | 0 | 32 | 32 | 1 | 1 | 173.1 | 130 | 77 | 64 | 72 | 172 | 16 | 11 |
| Griff McGarry | Bal | sp | 25 | 4.37 | 4 | 6 | 3 | 50 | 0 | 0 | 0 | 55.2 | 54 | 32 | 27 | 41 | 57 | 4 | 2 |
| Scott McGough | Hou | mr | 34 | 5.33 | 6 | 3 | 6 | 26 | 0 | 0 | 0 | 25.1 | 32 | 18 | 15 | 10 | 31 | 6 | 2 |
| Michael McGreevy | ChA | sp | 23 | 2.52 | 2 | 1 | 5 | 14 | 2 | 0 | 0 | 25.0 | 24 | 10 | 7 | 7 | 16 | 2 | 2 |
| Evan McKendry | SD | sp | 26 | 3.35 | 6 | 5 | 0 | 16 | 10 | 0 | 0 | 75.1 | 72 | 35 | 28 | 14 | 46 | 6 | 7 |
| Triston McKenzie | | sp | 26 | 4.87 | 10 | 14 | 0 | 34 | 34 | 1 | 0 | 207.0 | 223 | 122 | 112 | 47 | 170 | 35 | 7 |
| John McMillon | Pit | mr | 26 | 8.56 | 0 | 1 | 1 | 9 | 0 | 0 | 0 | 13.2 | 15 | 13 | 13 | 14 | 17 | 1 | 0 |
| John Means* | Tex | sp | 31 | 2.08 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 13.0 | 10 | 5 | 3 | 1 | 12 | 1 | 0 |
| Nick Mears | | mr | 27 | 6.75 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 8.0 | 6 | 7 | 6 | 8 | 3 | 1 | 1 |
| Trevor Megill | | mr | 30 | 3.99 | 1 | 3 | 4 | 35 | 0 | 0 | 0 | 38.1 | 29 | 18 | 17 | 15 | 56 | 6 | 1 |
| Tylor Megill | NYN | sp | 28 | 1.59 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 5.2 | 4 | 2 | 1 | 0 | 4 | 0 | 0 |
| Juan M. Mejia | Mia | mr | 23 | 5.40 | 1 | 1 | 1 | 7 | 0 | 0 | 0 | 10.0 | 7 | 6 | 6 | 3 | 7 | 2 | 1 |
| Cristian Mena | Col | sp | 21 | 6.09 | 3 | 15 | 0 | 24 | 23 | 1 | 1 | 125.2 | 138 | 99 | 85 | 44 | 107 | 24 | 6 |
| Michael Mercado | NYA | mr | 25 | 5.79 | 1 | 6 | 1 | 12 | 9 | 0 | 0 | 56.0 | 59 | 40 | 36 | 21 | 57 | 7 | 3 |
| Julian Merryweather | | mr | 32 | 1.37 | 1 | 2 | 1 | 14 | 0 | 0 | 0 | 19.2 | 16 | 3 | 3 | 2 | 31 | 2 | 0 |
| Max Meyer | ChA | sp | 25 | 4.37 | 10 | 11 | 0 | 32 | 32 | 1 | 0 | 177.0 | 168 | 100 | 86 | 61 | 168 | 26 | 10 |
| Miles Mikolas | StL | sp | 35 | 2.91 | 19 | 5 | 0 | 34 | 34 | 7 | 2 | 235.0 | 210 | 85 | 76 | 30 | 166 | 21 | 7 |
| Bobby Miller | Bal | sp | 25 | 2.76 | 14 | 4 | 0 | 34 | 27 | 1 | 0 | 182.1 | 156 | 62 | 56 | 51 | 173 | 11 | 9 |
| Bryce Miller | | sp | 25 | 3.30 | 14 | 12 | 0 | 37 | 36 | 2 | 1 | 234.1 | 214 | 103 | 86 | 49 | 199 | 24 | 12 |
| Erik Miller* | | mr | 26 | 6.51 | 1 | 1 | 1 | 17 | 0 | 0 | 0 | 27.2 | 29 | 23 | 20 | 20 | 47 | 6 | 0 |
| Mason Miller | Bos | mr | 25 | 2.16 | 3 | 2 | 6 | 61 | 0 | 0 | 0 | 79.1 | 39 | 23 | 19 | 31 | 98 | 5 | 2 |
| Tyson Miller | | mr | 28 | 5.93 | 1 | 2 | 2 | 27 | 0 | 0 | 0 | 30.1 | 39 | 24 | 20 | 9 | 31 | 4 | 1 |
| Hoby Milner* | Cin | mr | 33 | 2.47 | 3 | 3 | 1 | 44 | 0 | 0 | 0 | 43.2 | 34 | 15 | 12 | 11 | 46 | 4 | 2 |
| A.J. Minter* | Was | mr | 30 | 5.76 | 2 | 4 | 1 | 25 | 0 | 0 | 0 | 25.0 | 25 | 19 | 16 | 9 | 29 | 5 | 1 |
| Andrew Misiaszek* | Cin | mr | 26 | 2.84 | 1 | 0 | 0 | 7 | 0 | 0 | 0 | 6.1 | 6 | 4 | 2 | 6 | 4 | 0 | 2 |
| Jacob Misiorowski | Tex | sp | 22 | 6.36 | 1 | 5 | 0 | 20 | 7 | 0 | 0 | 58.0 | 57 | 42 | 41 | 39 | 69 | 7 | 1 |
| Casey Mize | | sp | 27 | 3.51 | 10 | 6 | 0 | 20 | 20 | 0 | 0 | 138.1 | 120 | 55 | 54 | 34 | 113 | 12 | 12 |
| Sam Moll* | Tor | mr | 32 | 4.11 | 1 | 1 | 0 | 16 | 0 | 0 | 0 | 15.1 | 13 | 7 | 7 | 3 | 16 | 2 | 0 |
| Frankie Montas | ChN | sp | 31 | 4.67 | 5 | 5 | 0 | 11 | 11 | 0 | 0 | 61.2 | 65 | 33 | 32 | 18 | 68 | 6 | 2 |
| Keider Montero | | sp | 23 | 4.60 | 2 | 1 | 0 | 11 | 0 | 0 | 0 | 15.2 | 15 | 12 | 8 | 2 | 12 | 2 | 0 |
| Jordan Montgomery* | | sp | 31 | 3.85 | 11 | 11 | 0 | 32 | 32 | 0 | 0 | 210.1 | 193 | 98 | 90 | 49 | 192 | 19 | 14 |
| Matt Moore* | Min | mr | 35 | 4.41 | 5 | 3 | 3 | 59 | 0 | 0 | 0 | 69.1 | 68 | 35 | 34 | 20 | 75 | 12 | 3 |
| Francisco Morales | LAN | mr | 24 | 2.33 | 1 | 0 | 0 | 44 | 0 | 0 | 0 | 58.0 | 40 | 16 | 15 | 28 | 59 | 2 | 6 |
| Adrian Morejon* | | mr | 25 | 5.49 | 1 | 2 | 0 | 45 | 0 | 0 | 0 | 41.0 | 45 | 27 | 25 | 14 | 38 | 6 | 2 |
| Eli Morgan | Det | mr | 28 | 2.76 | 7 | 5 | 0 | 21 | 21 | 0 | 0 | 127.0 | 92 | 44 | 39 | 25 | 141 | 7 | 2 |
| Charlie Morton | SD | sp | 40 | 3.42 | 11 | 8 | 0 | 31 | 31 | 2 | 1 | 210.2 | 168 | 91 | 80 | 83 | 220 | 21 | 20 |
| Kyle Muller* | Tor | sp | 26 | 4.61 | 1 | 1 | 1 | 26 | 0 | 0 | 0 | 27.1 | 36 | 15 | 14 | 8 | 28 | 3 | 2 |
| Andres Munoz | Sea | mr | 25 | 3.39 | 4 | 5 | 1 | 67 | 0 | 0 | 0 | 74.1 | 64 | 30 | 28 | 22 | 120 | 9 | 1 |
| Roddery Munoz | Tex | sp | 24 | 0.00 | 0 | 0 | 1 | 3 | 0 | 0 | 0 | 3.1 | 4 | 0 | 0 | 1 | 0 | 0 | 1 |
| Ryan Murphy | SF | sp | 24 | 4.35 | 3 | 6 | 1 | 14 | 12 | 0 | 0 | 68.1 | 71 | 43 | 33 | 23 | 51 | 8 | 4 |
| Joe Musgrove | | sp | 31 | 4.13 | 5 | 7 | 0 | 17 | 17 | 3 | 0 | 120.0 | 96 | 57 | 55 | 25 | 103 | 9 | 9 |
| Tobias Myers | | sp | 25 | 0.61 | 0 | 0 | 0 | 10 | 0 | 0 | 0 | 14.2 | 8 | 1 | 1 | 4 | 12 | 1 | 2 |
| Andrew Nardi* | Atl | mr | 25 | 4.88 | 3 | 5 | 5 | 53 | 0 | 0 | 0 | 66.1 | 54 | 40 | 36 | 29 | 77 | 15 | 2 |
| Nick Nastrini | SD | sp | 24 | 9.00 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.0 | 8 | 5 | 5 | 0 | 7 | 1 | 0 |
| Packy Naughton* | Was | sp | 28 | 3.53 | 5 | 2 | 2 | 17 | 11 | 0 | 0 | 79.0 | 73 | 37 | 31 | 17 | 57 | 10 | 8 |
| Jack Neely | | mr | 24 | 4.66 | 6 | 7 | 9 | 72 | 0 | 0 | 0 | 92.2 | 88 | 54 | 48 | 47 | 108 | 14 | 5 |
| Kyle Nelson* | Atl | mr | 27 | 2.84 | 0 | 0 | 2 | 8 | 0 | 0 | 0 | 6.1 | 7 | 2 | 2 | 1 | 7 | 0 | 0 |
| Ryne Nelson | Cin | sp | 26 | 3.98 | 6 | 10 | 0 | 27 | 25 | 0 | 0 | 151.1 | 153 | 68 | 67 | 32 | 114 | 19 | 11 |
| Hector Neris | Cin | mr | 35 | 2.30 | 8 | 5 | 3 | 58 | 0 | 0 | 0 | 70.1 | 43 | 22 | 18 | 23 | 86 | 8 | 3 |
| Kyle Nicolas | Atl | sp | 25 | 5.94 | 3 | 3 | 0 | 46 | 0 | 0 | 0 | 53.0 | 63 | 40 | 35 | 25 | 54 | 14 | 3 |
| Aaron Nola | Cle | sp | 31 | 2.91 | 14 | 7 | 0 | 33 | 33 | 4 | 3 | 244.0 | 209 | 83 | 79 | 32 | 262 | 21 | 7 |
| Dedniel Nunez | Tex | mr | 28 | 4.12 | 1 | 2 | 2 | 66 | 0 | 0 | 0 | 87.1 | 73 | 46 | 40 | 47 | 77 | 11 | 7 |
| Bailey Ober | | sp | 28 | 3.58 | 10 | 4 | 0 | 25 | 25 | 0 | 0 | 150.2 | 139 | 65 | 60 | 26 | 138 | 21 | 6 |
| Pierson Ohl | KC | sp | 24 | 4.48 | 14 | 12 | 0 | 31 | 31 | 3 | 0 | 198.2 | 225 | 107 | 99 | 18 | 149 | 25 | 9 |
| Shohei Ohtani | Tex | dh | 29 | 4.50 | 1 | 1 | 0 | 3 | 3 | 0 | 0 | 20.0 | 18 | 10 | 10 | 3 | 20 | 3 | 1 |
| Steven Okert* | KC | mr | 32 | 5.85 | 2 | 3 | 4 | 62 | 0 | 0 | 0 | 60.0 | 65 | 40 | 39 | 18 | 71 | 14 | 4 |
| Mat Olsen | NYN | mr | 23 | 3.87 | 5 | 5 | 7 | 70 | 0 | 0 | 0 | 100.0 | 86 | 51 | 43 | 29 | 95 | 16 | 6 |
| Reese Olson | | sp | 24 | 5.28 | 2 | 8 | 0 | 23 | 15 | 0 | 0 | 88.2 | 102 | 60 | 52 | 37 | 78 | 13 | 7 |
| Kaleb Ort | Hou | mr | 32 | 13.50 | 1 | 0 | 0 | 8 | 0 | 0 | 0 | 4.2 | 7 | 7 | 7 | 6 | 6 | 0 | 1 |
| Luis L. Ortiz | | sp | 25 | 9.19 | 3 | 5 | 0 | 37 | 5 | 0 | 0 | 63.2 | 77 | 68 | 65 | 31 | 56 | 10 | 7 |
| Michel Otanez | Tex | mr | 26 | 54.00 | 1 | 1 | 0 | 6 | 0 | 0 | 0 | 2.0 | 11 | 13 | 12 | 6 | 4 | 4 | 0 |
| Adam Ottavino | SD | mr | 38 | 5.32 | 4 | 4 | 2 | 39 | 0 | 0 | 0 | 47.1 | 57 | 31 | 28 | 22 | 56 | 2 | 5 |
| Chris Paddack | | sp | 28 | 2.97 | 10 | 6 | 0 | 23 | 23 | 0 | 0 | 139.1 | 110 | 53 | 46 | 24 | 142 | 15 | 4 |
| Emilio Pagan | ChA | mr | 33 | 2.18 | 4 | 0 | 3 | 39 | 0 | 0 | 0 | 41.1 | 22 | 12 | 10 | 16 | 35 | 2 | 1 |
| Daniel Palencia | Mia | mr | 24 | 0.00 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1.2 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
| Andre Pallante | Min | mr | 25 | 4.61 | 5 | 2 | 0 | 60 | 5 | 1 | 0 | 99.2 | 109 | 53 | 51 | 28 | 66 | 13 | 10 |
| Carson Palmquist* | Ari | sp | 23 | 2.18 | 5 | 2 | 0 | 24 | 1 | 0 | 0 | 45.1 | 32 | 14 | 11 | 16 | 49 | 4 | 4 |
| Enoli Paredes | NYA | mr | 28 | 7.11 | 2 | 6 | 3 | 47 | 0 | 0 | 0 | 49.1 | 56 | 44 | 39 | 25 | 50 | 13 | 3 |
| Mitchell Parker* | Atl | sp | 24 | 5.21 | 5 | 10 | 2 | 38 | 24 | 1 | 0 | 134.2 | 146 | 82 | 78 | 60 | 129 | 18 | 11 |
| Joel Payamps | Cin | mr | 30 | 4.91 | 2 | 0 | 1 | 32 | 0 | 0 | 0 | 44.0 | 45 | 24 | 24 | 18 | 36 | 5 | 3 |
| Nate Pearson | | mr | 27 | 4.28 | 2 | 4 | 2 | 62 | 0 | 0 | 0 | 80.0 | 68 | 39 | 38 | 42 | 99 | 11 | 3 |
| Elvis Peguero | | mr | 27 | 3.67 | 3 | 2 | 1 | 44 | 0 | 0 | 0 | 61.1 | 52 | 26 | 25 | 14 | 65 | 7 | 6 |
| Walter Pennington* | | mr | 26 | 3.29 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 13.2 | 14 | 5 | 5 | 8 | 17 | 0 | 1 |
| Ryan Pepiot | | sp | 26 | 2.78 | 4 | 10 | 1 | 35 | 30 | 0 | 0 | 174.2 | 122 | 58 | 54 | 68 | 164 | 21 | 13 |
| Freddy Peralta | | sp | 28 | 3.45 | 14 | 9 | 0 | 33 | 33 | 2 | 0 | 203.2 | 177 | 80 | 78 | 74 | 227 | 25 | 7 |
| Wandy Peralta* | SD | mr | 32 | 1.26 | 3 | 0 | 2 | 28 | 0 | 0 | 0 | 28.2 | 17 | 9 | 4 | 17 | 31 | 1 | 2 |
| Cionel Perez* | Mil | mr | 28 | 2.25 | 2 | 0 | 1 | 6 | 0 | 0 | 0 | 4.0 | 1 | 1 | 1 | 2 | 5 | 0 | 0 |
| Martin Perez* | LAN | sp | 33 | 4.10 | 11 | 14 | 0 | 32 | 32 | 5 | 1 | 208.1 | 221 | 99 | 95 | 37 | 156 | 27 | 22 |
| Jack Perkins | Bal | sp | 26 | 1.40 | 1 | 0 | 1 | 9 | 1 | 0 | 0 | 19.1 | 13 | 3 | 3 | 10 | 15 | 1 | 1 |
| David Peterson* | Oak | sp | 28 | 4.49 | 6 | 8 | 0 | 22 | 22 | 0 | 0 | 126.1 | 114 | 66 | 63 | 41 | 132 | 14 | 12 |
| Brandon Pfaadt | Col | sp | 25 | 4.17 | 10 | 11 | 1 | 39 | 31 | 2 | 0 | 211.2 | 208 | 123 | 98 | 54 | 205 | 25 | 11 |
| Evan Phillips | Mil | cl | 29 | 3.57 | 5 | 6 | 20 | 45 | 0 | 0 | 0 | 53.0 | 46 | 27 | 21 | 8 | 58 | 7 | 2 |
| Nick Pivetta | Was | sp | 31 | 4.94 | 5 | 9 | 0 | 18 | 18 | 0 | 0 | 109.1 | 88 | 63 | 60 | 36 | 104 | 27 | 5 |
| Colin Poche* | Col | mr | 30 | 6.53 | 1 | 6 | 4 | 41 | 0 | 0 | 0 | 41.1 | 41 | 35 | 30 | 22 | 49 | 7 | 0 |
| Cade Povich* | Bos | sp | 24 | 4.50 | 10 | 11 | 0 | 27 | 27 | 0 | 0 | 160.0 | 157 | 89 | 80 | 51 | 149 | 26 | 6 |
| Ryan Pressly | Cin | cl | 35 | 1.83 | 8 | 4 | 33 | 64 | 0 | 0 | 0 | 69.0 | 54 | 20 | 14 | 17 | 76 | 4 | 4 |
| A.J. Puk* | LAN | mr | 29 | 0.00 | 1 | 0 | 0 | 10 | 0 | 0 | 0 | 9.2 | 1 | 0 | 0 | 2 | 15 | 0 | 0 |
| Jose Quijada* | Mia | mr | 28 | 4.32 | 0 | 1 | 0 | 8 | 0 | 0 | 0 | 8.1 | 5 | 4 | 4 | 4 | 8 | 3 | 0 |
| Jose Quintana* | Pit | sp | 35 | 4.14 | 8 | 10 | 0 | 25 | 25 | 2 | 1 | 156.2 | 151 | 73 | 72 | 42 | 140 | 13 | 12 |
| Cole Ragans* | Was | sp | 26 | 4.05 | 9 | 5 | 0 | 17 | 17 | 0 | 0 | 115.2 | 102 | 54 | 52 | 21 | 121 | 17 | 6 |
| Taylor Rashi | ChN | mr | 28 | 3.65 | 9 | 4 | 0 | 16 | 15 | 0 | 0 | 86.1 | 68 | 36 | 35 | 27 | 77 | 6 | 4 |
| Drew Rasmussen | Bos | sp | 28 | 2.47 | 4 | 3 | 0 | 9 | 9 | 0 | 0 | 58.1 | 38 | 16 | 16 | 22 | 51 | 1 | 1 |
| Robbie Ray* | StL | sp | 32 | 5.34 | 2 | 3 | 0 | 6 | 6 | 1 | 1 | 32.0 | 44 | 23 | 19 | 9 | 25 | 6 | 5 |
| Marco Raya | Mia | sp | 21 | 5.76 | 2 | 6 | 1 | 19 | 11 | 0 | 0 | 75.0 | 74 | 51 | 48 | 22 | 59 | 18 | 2 |
| Colin Rea | Mil | sp | 33 | 3.31 | 1 | 1 | 0 | 6 | 5 | 0 | 0 | 35.1 | 35 | 16 | 13 | 3 | 30 | 6 | 6 |
| Sean Reid-Foley | | mr | 28 | 4.09 | 0 | 1 | 0 | 9 | 0 | 0 | 0 | 11.0 | 13 | 5 | 5 | 8 | 15 | 0 | 1 |
| Sean Reynolds | Mia | mr | 26 | 4.76 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 5.2 | 4 | 3 | 3 | 3 | 3 | 1 | 0 |
| Trevor Richards | NYN | mr | 31 | 4.34 | 11 | 10 | 0 | 33 | 33 | 0 | 0 | 178.1 | 153 | 92 | 86 | 64 | 218 | 30 | 7 |
| Sem Robberse | Pit | sp | 22 | 3.75 | 8 | 13 | 0 | 31 | 31 | 3 | 1 | 185.0 | 178 | 91 | 77 | 48 | 144 | 14 | 11 |
| Ethan Roberts | Oak | mr | 26 | 3.75 | 1 | 0 | 1 | 37 | 3 | 0 | 0 | 57.2 | 50 | 25 | 24 | 12 | 54 | 3 | 6 |
| David Robertson | | cl | 39 | 7.06 | 4 | 2 | 9 | 26 | 0 | 0 | 0 | 29.1 | 32 | 23 | 23 | 9 | 28 | 6 | 1 |
| Nick Robertson | Cin | mr | 25 | 3.64 | 3 | 1 | 3 | 36 | 0 | 0 | 0 | 47.0 | 46 | 21 | 19 | 11 | 43 | 5 | 2 |
| Joe Rock* | Cle | sp | 23 | 2.83 | 11 | 4 | 0 | 20 | 19 | 1 | 1 | 127.1 | 99 | 42 | 40 | 32 | 117 | 12 | 8 |
| Carlos Rodon* | ChA | sp | 31 | 3.73 | 5 | 14 | 0 | 33 | 33 | 1 | 0 | 207.2 | 173 | 96 | 86 | 72 | 238 | 24 | 8 |
| Carlos F. Rodriguez | Tor | sp | 22 | 5.27 | 1 | 1 | 0 | 25 | 2 | 0 | 0 | 42.2 | 37 | 30 | 25 | 15 | 43 | 5 | 5 |
| Eduardo Rodriguez* | Min | sp | 31 | 6.47 | 3 | 4 | 0 | 10 | 10 | 0 | 0 | 48.2 | 59 | 37 | 35 | 15 | 42 | 6 | 6 |
| Grayson Rodriguez | Tex | sp | 24 | 2.85 | 12 | 6 | 0 | 22 | 22 | 1 | 0 | 145.1 | 114 | 49 | 46 | 38 | 157 | 20 | 8 |
| Manuel Rodriguez | Pit | mr | 27 | 1.86 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 9.2 | 8 | 2 | 2 | 5 | 8 | 1 | 0 |
| Randy Rodriguez | Hou | mr | 24 | 8.10 | 0 | 1 | 0 | 4 | 0 | 0 | 0 | 3.1 | 2 | 4 | 3 | 2 | 5 | 0 | 0 |
| Yariel Rodriguez | ChN | mr | 27 | 5.93 | 2 | 2 | 2 | 32 | 1 | 0 | 0 | 41.0 | 40 | 29 | 27 | 16 | 44 | 5 | 6 |
| Yerry Rodriguez | LAN | mr | 26 | 7.28 | 1 | 5 | 0 | 43 | 0 | 0 | 0 | 38.1 | 51 | 35 | 31 | 18 | 36 | 5 | 6 |
| Taylor Rogers* | Ari | mr | 33 | 1.29 | 2 | 3 | 4 | 50 | 0 | 0 | 0 | 55.2 | 31 | 12 | 8 | 11 | 69 | 2 | 10 |
| Trevor Rogers* | SF | sp | 26 | 4.34 | 4 | 7 | 3 | 28 | 14 | 1 | 0 | 112.0 | 121 | 59 | 54 | 28 | 118 | 15 | 7 |
| Tyler Rogers | StL | mr | 33 | 2.59 | 5 | 3 | 3 | 62 | 0 | 0 | 0 | 76.1 | 62 | 24 | 22 | 10 | 54 | 7 | 6 |
| Jordan Romano | Cle | cl | 31 | 1.90 | 1 | 1 | 6 | 19 | 0 | 0 | 0 | 23.2 | 15 | 10 | 5 | 5 | 32 | 4 | 4 |
| JoJo Romero* | | mr | 27 | 3.01 | 10 | 3 | 12 | 56 | 1 | 0 | 0 | 71.2 | 58 | 33 | 24 | 17 | 81 | 9 | 5 |
| Landen Roupp | | sp | 25 | 4.76 | 4 | 6 | 0 | 39 | 16 | 0 | 0 | 121.0 | 123 | 75 | 64 | 53 | 87 | 25 | 5 |
| Jackson Rutledge | SF | sp | 25 | 4.31 | 2 | 5 | 0 | 11 | 11 | 1 | 0 | 77.1 | 90 | 42 | 37 | 23 | 54 | 6 | 0 |
| Joe Ryan | Mia | sp | 28 | 3.31 | 12 | 5 | 0 | 27 | 27 | 2 | 1 | 182.1 | 144 | 69 | 67 | 38 | 184 | 24 | 4 |
| Andrew Saalfrank* | Mia | mr | 26 | 3.52 | 3 | 0 | 2 | 30 | 0 | 0 | 0 | 38.1 | 28 | 19 | 15 | 16 | 40 | 3 | 4 |
| Chris Sale* | LAA | sp | 35 | 3.21 | 13 | 7 | 0 | 27 | 27 | 0 | 0 | 151.1 | 118 | 58 | 54 | 33 | 199 | 13 | 10 |
| Cristopher Sanchez* | Tam | sp | 27 | 3.14 | 11 | 10 | 0 | 32 | 32 | 0 | 0 | 197.2 | 190 | 73 | 69 | 31 | 169 | 18 | 21 |
| Nick Sandlin | Atl | mr | 27 | 3.95 | 7 | 3 | 2 | 69 | 0 | 0 | 0 | 79.2 | 70 | 38 | 35 | 31 | 77 | 10 | 10 |
| Patrick Sandoval* | | sp | 27 | 5.79 | 4 | 2 | 3 | 32 | 2 | 0 | 0 | 42.0 | 50 | 30 | 27 | 19 | 45 | 1 | 4 |
| Cole Sands | | mr | 26 | 3.13 | 3 | 7 | 4 | 67 | 0 | 0 | 0 | 74.2 | 67 | 30 | 26 | 20 | 71 | 5 | 3 |
| Tony Santillan | Col | mr | 27 | 4.81 | 3 | 4 | 1 | 27 | 5 | 0 | 0 | 48.2 | 53 | 32 | 26 | 38 | 41 | 4 | 7 |
| Gregory Santos | LAA | mr | 24 | 3.06 | 2 | 0 | 1 | 15 | 0 | 0 | 0 | 17.2 | 13 | 9 | 6 | 5 | 19 | 1 | 0 |
| Tayler Saucedo* | Mil | mr | 31 | 5.19 | 1 | 3 | 1 | 22 | 0 | 0 | 0 | 26.0 | 23 | 15 | 15 | 5 | 26 | 5 | 6 |
| Josh Sborz | SD | mr | 30 | 1.37 | 4 | 2 | 1 | 16 | 0 | 0 | 0 | 19.2 | 11 | 5 | 3 | 9 | 27 | 1 | 1 |
| Max Scherzer | | sp | 39 | 3.26 | 2 | 1 | 0 | 6 | 6 | 0 | 0 | 38.2 | 38 | 16 | 14 | 7 | 33 | 6 | 3 |
| Clarke Schmidt | Col | sp | 28 | 5.97 | 3 | 12 | 0 | 19 | 19 | 1 | 1 | 107.0 | 102 | 88 | 71 | 51 | 100 | 11 | 4 |
| John Schreiber | ChA | mr | 30 | 3.79 | 2 | 0 | 3 | 47 | 0 | 0 | 0 | 61.2 | 55 | 31 | 26 | 22 | 54 | 9 | 6 |
| Christian Scott | | sp | 25 | 4.10 | 7 | 6 | 0 | 21 | 21 | 0 | 0 | 125.0 | 121 | 61 | 57 | 27 | 98 | 10 | 6 |
| Tanner Scott* | NYN | mr | 29 | 3.99 | 7 | 4 | 7 | 50 | 0 | 0 | 0 | 67.2 | 51 | 31 | 30 | 25 | 89 | 8 | 5 |
| Tayler Scott | Phi | mr | 32 | 5.95 | 2 | 4 | 1 | 22 | 3 | 0 | 0 | 39.1 | 40 | 28 | 26 | 21 | 40 | 4 | 5 |
| JP Sears* | Cin | sp | 28 | 3.80 | 4 | 6 | 0 | 24 | 12 | 0 | 0 | 85.1 | 81 | 40 | 36 | 23 | 60 | 14 | 7 |
| Luis Severino | Tex | sp | 30 | 5.62 | 5 | 15 | 0 | 32 | 32 | 1 | 0 | 177.2 | 198 | 119 | 111 | 65 | 166 | 29 | 9 |
| Paul Sewald | LAA | cl | 34 | 2.96 | 2 | 6 | 5 | 40 | 0 | 0 | 0 | 48.2 | 42 | 22 | 16 | 16 | 49 | 8 | 1 |
| Ian Seymour* | Mia | sp | 25 | 5.31 | 2 | 2 | 0 | 4 | 4 | 0 | 0 | 20.1 | 19 | 13 | 12 | 2 | 23 | 2 | 1 |
| Davis Sharpe | Atl | mr | 24 | 3.61 | 1 | 5 | 5 | 88 | 0 | 0 | 0 | 124.2 | 120 | 54 | 50 | 22 | 123 | 15 | 6 |
| Chase Silseth | Sea | sp | 24 | 3.33 | 6 | 2 | 0 | 9 | 9 | 0 | 0 | 51.1 | 36 | 19 | 19 | 18 | 58 | 6 | 2 |
| Lucas Sims | Col | mr | 30 | 7.05 | 1 | 3 | 2 | 39 | 0 | 0 | 0 | 44.2 | 48 | 37 | 35 | 30 | 62 | 10 | 1 |
| Brady Singer | LAN | sp | 27 | 3.34 | 10 | 15 | 0 | 33 | 33 | 3 | 1 | 223.2 | 211 | 92 | 83 | 51 | 216 | 26 | 18 |
| Tarik Skubal* | Tam | sp | 27 | 4.65 | 10 | 13 | 0 | 34 | 34 | 2 | 1 | 214.2 | 226 | 118 | 111 | 42 | 205 | 27 | 11 |
| Cade Smith | Tam | mr | 25 | 4.66 | 1 | 3 | 2 | 53 | 0 | 0 | 0 | 65.2 | 51 | 40 | 34 | 30 | 71 | 6 | 5 |
| Drew Smith | NYN | mr | 30 | 3.80 | 2 | 2 | 2 | 16 | 0 | 0 | 0 | 21.1 | 16 | 10 | 9 | 7 | 25 | 0 | 0 |
| Will Smith* | ChN | cl | 34 | 3.92 | 5 | 2 | 2 | 57 | 0 | 0 | 0 | 62.0 | 53 | 29 | 27 | 29 | 64 | 13 | 4 |
| AJ Smith-Shawver | Tex | sp | 21 | 6.16 | 1 | 3 | 0 | 25 | 7 | 0 | 0 | 57.0 | 51 | 40 | 39 | 34 | 57 | 8 | 3 |
| Blake Snell* | Cin | sp | 31 | 3.90 | 12 | 8 | 0 | 26 | 26 | 0 | 0 | 154.2 | 126 | 72 | 67 | 79 | 196 | 20 | 11 |
| Robby Snelling* | Bal | sp | 20 | 3.96 | 11 | 11 | 3 | 58 | 28 | 0 | 0 | 204.2 | 180 | 99 | 90 | 83 | 148 | 22 | 13 |
| Collin Snider | Bos | mr | 28 | 9.26 | 0 | 0 | 1 | 7 | 0 | 0 | 0 | 11.2 | 17 | 12 | 12 | 4 | 11 | 3 | 3 |
| Jose Soriano | | mr | 25 | 4.85 | 5 | 7 | 0 | 29 | 23 | 0 | 0 | 115.0 | 97 | 66 | 62 | 48 | 135 | 24 | 10 |
| Mike Soroka | Ari | sp | 26 | 1.84 | 0 | 0 | 1 | 12 | 0 | 0 | 0 | 14.2 | 16 | 3 | 3 | 0 | 12 | 0 | 1 |
| Gregory Soto* | Cle | mr | 29 | 3.22 | 1 | 5 | 4 | 51 | 0 | 0 | 0 | 50.1 | 37 | 19 | 18 | 17 | 69 | 6 | 4 |
| Gabe Speier* | Was | mr | 29 | 2.79 | 1 | 0 | 1 | 23 | 0 | 0 | 0 | 29.0 | 29 | 13 | 9 | 5 | 26 | 1 | 4 |
| Mitch Spence | SF | sp | 26 | 4.15 | 2 | 9 | 0 | 17 | 16 | 0 | 0 | 108.1 | 99 | 52 | 50 | 29 | 90 | 7 | 10 |
| Carson Spiers | Cle | sp | 26 | 1.29 | 1 | 0 | 0 | 6 | 0 | 0 | 0 | 7.0 | 5 | 1 | 1 | 0 | 6 | 0 | 1 |
| Jeffrey Springs* | Bos | sp | 31 | 2.62 | 6 | 0 | 0 | 8 | 8 | 1 | 0 | 58.1 | 36 | 17 | 17 | 10 | 62 | 8 | 4 |
| Garrett Stallings | LAA | sp | 26 | 5.11 | 3 | 4 | 0 | 16 | 9 | 0 | 0 | 61.2 | 71 | 39 | 35 | 19 | 51 | 13 | 4 |
| Ryne Stanek | | mr | 32 | 4.01 | 4 | 0 | 1 | 37 | 0 | 0 | 0 | 42.2 | 33 | 20 | 19 | 12 | 46 | 1 | 3 |
| Cody Stashak | Cle | mr | 30 | 4.17 | 2 | 4 | 1 | 37 | 0 | 0 | 0 | 41.0 | 47 | 26 | 19 | 9 | 51 | 8 | 2 |
| Josh Staumont | Phi | mr | 30 | 1.93 | 0 | 0 | 1 | 8 | 0 | 0 | 0 | 9.1 | 5 | 3 | 2 | 5 | 11 | 0 | 0 |
| Justin Steele* | Tex | sp | 28 | 3.37 | 12 | 6 | 0 | 26 | 26 | 1 | 0 | 173.2 | 139 | 75 | 65 | 44 | 162 | 15 | 6 |
| Brock Stewart | Tex | mr | 32 | 5.03 | 1 | 2 | 6 | 22 | 0 | 0 | 0 | 19.2 | 13 | 14 | 11 | 9 | 27 | 4 | 2 |
| Gavin Stone | | sp | 25 | 4.28 | 5 | 9 | 2 | 50 | 13 | 0 | 0 | 111.1 | 111 | 60 | 53 | 26 | 95 | 15 | 6 |
| Matt Strahm* | Tor | mr | 32 | 4.01 | 8 | 8 | 4 | 38 | 16 | 0 | 0 | 114.1 | 103 | 61 | 51 | 36 | 120 | 15 | 2 |
| Hunter Stratton | | mr | 27 | 3.78 | 1 | 1 | 5 | 29 | 0 | 0 | 0 | 33.1 | 32 | 15 | 14 | 14 | 38 | 4 | 3 |
| Spencer Strider | Sea | sp | 25 | 1.46 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 12.1 | 6 | 2 | 2 | 5 | 22 | 1 | 0 |
| Marcus Stroman | Tam | sp | 33 | 4.19 | 11 | 14 | 0 | 33 | 33 | 1 | 1 | 208.1 | 206 | 105 | 97 | 59 | 161 | 15 | 15 |
| Peter Strzelecki | KC | mr | 29 | 4.19 | 2 | 11 | 5 | 84 | 0 | 0 | 0 | 92.1 | 80 | 49 | 43 | 31 | 97 | 10 | 4 |
| Jose Suarez* | | sp | 26 | 3.86 | 2 | 3 | 1 | 23 | 5 | 0 | 0 | 58.1 | 52 | 29 | 25 | 14 | 65 | 8 | 4 |
| Ranger Suarez* | ChN | sp | 28 | 3.22 | 11 | 10 | 0 | 30 | 30 | 1 | 0 | 192.2 | 177 | 77 | 69 | 65 | 165 | 21 | 27 |
| Robert Suarez | Tam | mr | 33 | 3.90 | 5 | 5 | 8 | 56 | 0 | 0 | 0 | 57.2 | 37 | 29 | 25 | 41 | 59 | 12 | 3 |
| Brent Suter* | LAN | mr | 34 | 3.23 | 5 | 2 | 2 | 36 | 0 | 0 | 0 | 47.1 | 38 | 21 | 17 | 14 | 45 | 5 | 2 |
| Erik Swanson | SD | mr | 30 | 3.55 | 2 | 7 | 28 | 47 | 0 | 0 | 0 | 45.2 | 51 | 26 | 18 | 10 | 54 | 3 | 2 |
| Devin Sweet | Oak | mr | 27 | 3.28 | 4 | 1 | 1 | 32 | 0 | 0 | 0 | 46.2 | 44 | 23 | 17 | 12 | 51 | 6 | 2 |
| Jameson Taillon | Tam | sp | 32 | 3.57 | 11 | 5 | 0 | 27 | 27 | 2 | 1 | 176.1 | 154 | 72 | 70 | 38 | 158 | 15 | 8 |
| Dillon Tate | StL | mr | 30 | 4.43 | 0 | 0 | 2 | 15 | 0 | 0 | 0 | 20.1 | 15 | 12 | 10 | 9 | 13 | 2 | 2 |
| Dylan Tebrake | SD | mr | 24 | 2.88 | 5 | 3 | 3 | 44 | 0 | 0 | 0 | 59.1 | 36 | 19 | 19 | 22 | 62 | 6 | 4 |
| Caleb Thielbar* | Pit | mr | 37 | 3.75 | 4 | 4 | 1 | 58 | 0 | 0 | 0 | 60.0 | 45 | 28 | 25 | 16 | 66 | 9 | 3 |
| Ryan Thompson | Bos | mr | 32 | 3.62 | 3 | 3 | 6 | 56 | 0 | 0 | 0 | 64.2 | 61 | 29 | 26 | 16 | 51 | 13 | 8 |
| Zack Thompson* | SF | sp | 26 | 3.33 | 12 | 1 | 4 | 51 | 8 | 0 | 0 | 94.2 | 83 | 39 | 35 | 44 | 73 | 7 | 10 |
| Trent Thornton | Mil | mr | 30 | 5.28 | 0 | 0 | 0 | 24 | 0 | 0 | 0 | 30.2 | 34 | 18 | 18 | 11 | 26 | 6 | 4 |
| Ricky Tiedemann* | Tex | sp | 21 | 2.57 | 2 | 1 | 2 | 6 | 0 | 0 | 0 | 7.0 | 6 | 5 | 2 | 5 | 7 | 0 | 1 |
| Michael Tonkin | NYN | mr | 34 | 0.00 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 3.0 | 2 | 0 | 0 | 1 | 2 | 0 | 1 |
| Blake Treinen | Pit | mr | 36 | 5.40 | 0 | 1 | 0 | 11 | 0 | 0 | 0 | 11.2 | 15 | 8 | 7 | 5 | 11 | 1 | 0 |
| Edwin Uceta | Pit | mr | 26 | 4.79 | 1 | 2 | 1 | 10 | 2 | 0 | 0 | 20.2 | 23 | 14 | 11 | 7 | 11 | 2 | 1 |
| Abner Uribe | Sea | mr | 24 | 3.86 | 1 | 1 | 0 | 13 | 0 | 0 | 0 | 16.1 | 13 | 7 | 7 | 9 | 25 | 1 | 0 |
| Framber Valdez* | LAA | sp | 30 | 2.95 | 17 | 7 | 0 | 29 | 29 | 4 | 3 | 189.1 | 151 | 68 | 62 | 51 | 180 | 12 | 22 |
| Reid VanScoter* | KC | sp | 25 | 4.37 | 6 | 17 | 0 | 30 | 30 | 4 | 1 | 195.2 | 224 | 108 | 95 | 28 | 143 | 25 | 14 |
| Louie Varland | Atl | sp | 26 | 4.94 | 9 | 10 | 1 | 45 | 21 | 0 | 0 | 155.0 | 173 | 90 | 85 | 47 | 139 | 20 | 8 |
| Mike Vasil | Ari | sp | 24 | 4.01 | 9 | 5 | 1 | 30 | 23 | 0 | 0 | 139.0 | 130 | 64 | 62 | 44 | 129 | 22 | 8 |
| Randy Vasquez | Det | sp | 25 | 5.68 | 0 | 2 | 0 | 4 | 2 | 0 | 0 | 12.2 | 11 | 8 | 8 | 5 | 14 | 4 | 0 |
| Justin Verlander | SD | sp | 41 | 2.73 | 9 | 3 | 0 | 16 | 16 | 2 | 1 | 112.0 | 95 | 38 | 34 | 32 | 84 | 9 | 6 |
| Alex Vesia* | Atl | mr | 28 | 3.79 | 3 | 5 | 24 | 55 | 0 | 0 | 0 | 61.2 | 36 | 30 | 26 | 34 | 74 | 5 | 1 |
| Nick Vespi* | Det | mr | 28 | 3.00 | 3 | 3 | 3 | 43 | 0 | 0 | 0 | 63.0 | 55 | 24 | 21 | 13 | 42 | 10 | 10 |
| Will Vest | | mr | 29 | 6.55 | 3 | 5 | 1 | 25 | 2 | 0 | 0 | 33.0 | 42 | 34 | 24 | 12 | 34 | 6 | 4 |
| Thyago Vieira | Mia | mr | 30 | 0.00 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 2.1 | 1 | 0 | 0 | 1 | 3 | 0 | 0 |
| Darius Vines | Tor | sp | 26 | 3.00 | 0 | 0 | 1 | 11 | 0 | 0 | 0 | 12.0 | 7 | 4 | 4 | 4 | 8 | 0 | 1 |
| Victor Vodnik | NYA | mr | 24 | 4.88 | 0 | 1 | 4 | 44 | 0 | 0 | 0 | 48.0 | 40 | 31 | 26 | 23 | 40 | 6 | 2 |
| Austin Voth | NYN | mr | 32 | 3.19 | 12 | 7 | 0 | 32 | 32 | 0 | 0 | 166.1 | 143 | 62 | 59 | 50 | 141 | 19 | 6 |
| Michael Wacha | | sp | 32 | 4.71 | 4 | 5 | 2 | 30 | 9 | 0 | 0 | 84.0 | 79 | 48 | 44 | 21 | 72 | 12 | 7 |
| Hurston Waldrep | Atl | sp | 22 | 3.46 | 3 | 3 | 0 | 9 | 9 | 0 | 0 | 52.0 | 52 | 22 | 20 | 21 | 58 | 5 | 2 |
| Matt Waldron | | sp | 27 | 4.14 | 11 | 12 | 0 | 32 | 32 | 2 | 1 | 187.0 | 179 | 97 | 86 | 46 | 149 | 30 | 7 |
| Ryan Walker | | mr | 28 | 4.58 | 3 | 2 | 9 | 40 | 3 | 0 | 0 | 53.0 | 59 | 29 | 27 | 15 | 70 | 8 | 3 |
| Taijuan Walker | | sp | 31 | 3.04 | 3 | 4 | 0 | 8 | 8 | 0 | 0 | 50.1 | 50 | 20 | 17 | 13 | 46 | 7 | 4 |
| Blake Walston* | ChN | sp | 23 | 3.32 | 4 | 3 | 0 | 16 | 16 | 1 | 1 | 100.1 | 69 | 43 | 37 | 41 | 88 | 6 | 8 |
| Will Warren | ChN | sp | 25 | 5.17 | 2 | 8 | 2 | 34 | 5 | 0 | 0 | 55.2 | 52 | 36 | 32 | 29 | 38 | 8 | 4 |
| Ryan Weathers* | Col | sp | 24 | 5.09 | 0 | 1 | 1 | 16 | 0 | 0 | 0 | 23.0 | 28 | 16 | 13 | 10 | 16 | 1 | 4 |
| Luke Weaver | Tam | sp | 30 | 4.26 | 1 | 1 | 0 | 43 | 0 | 0 | 0 | 38.0 | 45 | 19 | 18 | 17 | 32 | 6 | 2 |
| Jacob Webb | Mil | mr | 30 | 6.15 | 3 | 1 | 0 | 40 | 0 | 0 | 0 | 52.2 | 56 | 37 | 36 | 11 | 65 | 10 | 1 |
| Logan Webb | Oak | sp | 27 | 2.99 | 15 | 10 | 0 | 33 | 33 | 8 | 5 | 228.2 | 197 | 83 | 76 | 25 | 172 | 21 | 13 |
| Tyler Wells | StL | sp | 29 | 3.00 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 12.0 | 8 | 4 | 4 | 6 | 9 | 1 | 2 |
| Joey Wentz* | | sp | 26 | 2.95 | 0 | 0 | 1 | 12 | 0 | 0 | 0 | 18.1 | 14 | 6 | 6 | 5 | 17 | 2 | 1 |
| Hayden Wesneski | Col | sp | 26 | 4.45 | 5 | 4 | 2 | 37 | 8 | 0 | 0 | 83.0 | 74 | 47 | 41 | 24 | 75 | 14 | 3 |
| Zack Wheeler | | sp | 34 | 3.38 | 13 | 10 | 0 | 34 | 34 | 3 | 1 | 242.2 | 210 | 103 | 91 | 55 | 237 | 16 | 12 |
| Carson Whisenhunt* | KC | sp | 23 | 2.25 | 1 | 2 | 1 | 6 | 1 | 0 | 0 | 12.0 | 8 | 4 | 3 | 9 | 15 | 0 | 1 |
| Brendan White | Was | mr | 25 | 3.19 | 2 | 1 | 1 | 14 | 2 | 0 | 0 | 31.0 | 33 | 11 | 11 | 12 | 25 | 2 | 2 |
| Garrett Whitlock | Oak | mr | 28 | 2.91 | 1 | 1 | 0 | 4 | 4 | 0 | 0 | 21.2 | 20 | 7 | 7 | 10 | 22 | 2 | 1 |
| Jordan Wicks* | Tam | sp | 24 | 3.20 | 1 | 0 | 0 | 4 | 4 | 0 | 0 | 25.1 | 19 | 10 | 9 | 3 | 21 | 2 | 0 |
| Brad Wieck* | Cle | mr | 32 | 8.00 | 1 | 2 | 0 | 17 | 0 | 0 | 0 | 18.0 | 21 | 17 | 16 | 14 | 30 | 2 | 1 |
| Devin Williams | | cl | 29 | 6.86 | 1 | 3 | 4 | 19 | 0 | 0 | 0 | 21.0 | 19 | 18 | 16 | 14 | 28 | 2 | 1 |
| Gavin Williams | Ari | sp | 24 | 1.82 | 2 | 1 | 1 | 10 | 2 | 0 | 0 | 24.2 | 22 | 7 | 5 | 8 | 22 | 0 | 2 |
| Brandon Williamson* | Col | sp | 26 | 5.93 | 0 | 3 | 0 | 4 | 2 | 0 | 0 | 13.2 | 17 | 10 | 9 | 9 | 11 | 1 | 4 |
| Bryse Wilson | Tor | mr | 26 | 4.01 | 7 | 4 | 0 | 14 | 14 | 0 | 0 | 89.2 | 99 | 41 | 40 | 15 | 59 | 12 | 9 |
| Steven Wilson | Det | mr | 29 | 4.88 | 1 | 1 | 1 | 19 | 0 | 0 | 0 | 24.0 | 26 | 13 | 13 | 15 | 20 | 3 | 4 |
| Allan Winans | SD | sp | 28 | 3.38 | 11 | 3 | 0 | 29 | 20 | 0 | 0 | 141.0 | 119 | 58 | 53 | 30 | 121 | 10 | 11 |
| Josh Winckowski | KC | mr | 26 | 3.70 | 9 | 6 | 0 | 36 | 19 | 0 | 0 | 131.1 | 118 | 61 | 54 | 43 | 113 | 15 | 12 |
| Josh Winder | Mia | mr | 27 | 2.70 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 3.1 | 1 | 1 | 1 | 3 | 3 | 0 | 0 |
| Keaton Winn | SF | sp | 26 | 5.35 | 1 | 7 | 0 | 12 | 11 | 0 | 0 | 67.1 | 77 | 45 | 40 | 15 | 69 | 6 | 4 |
| Bryan Woo | Bos | sp | 24 | 3.06 | 11 | 5 | 0 | 21 | 21 | 2 | 2 | 129.1 | 105 | 45 | 44 | 31 | 130 | 13 | 14 |
| Alex Wood* | ChN | sp | 33 | 2.43 | 3 | 1 | 0 | 9 | 9 | 0 | 0 | 59.1 | 47 | 16 | 16 | 8 | 57 | 1 | 6 |
| Simeon Woods Richardso | | sp | 23 | 4.24 | 0 | 1 | 1 | 18 | 0 | 0 | 0 | 23.1 | 22 | 11 | 11 | 10 | 23 | 2 | 1 |
| Yoshinobu Yamamoto | Col | sp | 25 | 3.35 | 6 | 6 | 0 | 16 | 16 | 0 | 0 | 99.1 | 90 | 43 | 37 | 22 | 88 | 11 | 3 |
| Kirby Yates | StL | mr | 37 | 1.54 | 1 | 1 | 1 | 10 | 0 | 0 | 0 | 11.2 | 8 | 4 | 2 | 11 | 16 | 0 | 1 |
| Huascar Ynoa | Mil | sp | 26 | 4.05 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 6.2 | 3 | 4 | 3 | 1 | 7 | 0 | 0 |
| Brandon Young | Hou | sp | 25 | 3.28 | 2 | 1 | 2 | 7 | 3 | 0 | 0 | 24.2 | 27 | 10 | 9 | 6 | 19 | 2 | 1 |
| Ryan Zeferjahn | Bos | mr | 26 | 4.50 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 6.0 | 6 | 3 | 3 | 1 | 1 | 2 | 2 |
| Angel Zerpa* | Bal | sp | 24 | 4.91 | 2 | 5 | 2 | 37 | 0 | 0 | 0 | 55.0 | 60 | 36 | 30 | 22 | 33 | 6 | 5 |
| Yosver Zulueta | Col | mr | 26 | 11.60 | 0 | 7 | 0 | 22 | 6 | 0 | 0 | 45.0 | 66 | 68 | 58 | 35 | 42 | 11 | 3 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| Andrew Abbott* | | sp | 25 | 15 | 10 | 1 | 2 | 3 | 0 | 0 | 5 | 9.3 | 2.9 | 12.3 | 10.2 | 1.3 | 3.5 | 1.35 |
| Mick Abel | Sea | sp | 22 | 3 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 9.9 | 2.9 | 13.4 | 10.4 | 1.3 | 3.5 | 1.43 |
| Bryan Abreu | Sea | mr | 27 | 4 | 1 | 0 | 4 | 5 | 1 | 0 | 0 | 5.5 | 3.6 | 9.5 | 13.2 | 0.7 | 3.7 | 1.01 |
| Jason Adam | Ari | mr | 32 | 9 | 3 | 0 | 10 | 2 | 1 | 0 | 0 | 5.3 | 2.7 | 9.1 | 9.9 | 1.3 | 3.7 | 0.89 |
| Austin L. Adams | Hou | mr | 33 | 1 | 2 | 0 | 4 | 0 | 0 | 0 | 0 | 6.8 | 7.6 | 17.7 | 12.7 | 0.8 | 1.7 | 1.59 |
| Ty Adcock | Det | mr | 27 | 3 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 7.6 | 1.5 | 9.7 | 9.1 | 1.0 | 6.1 | 1.02 |
| Keegan Akin* | LAA | mr | 29 | 1 | 0 | 2 | 3 | 1 | 0 | 0 | 2 | 9.8 | 3.2 | 13.5 | 10.1 | 1.3 | 3.2 | 1.44 |
| Jorge Alcala | Bal | mr | 28 | 13 | 2 | 4 | 8 | 4 | 1 | 0 | 0 | 6.7 | 2.9 | 10.2 | 9.3 | 0.8 | 3.2 | 1.06 |
| Franco Aleman | Col | mr | 24 | 6 | 1 | 0 | 5 | 11 | 1 | 0 | 2 | 9.7 | 3.3 | 13.9 | 9.9 | 0.7 | 3.0 | 1.44 |
| Scott Alexander* | | mr | 34 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 13.8 | 1.7 | 16.0 | 6.6 | 2.2 | 4.0 | 1.71 |
| Tyler Alexander* | ChA | mr | 29 | 10 | 8 | 1 | 7 | 4 | 3 | 0 | 6 | 9.9 | 0.9 | 11.1 | 8.2 | 1.8 | 8.9 | 1.20 |
| Logan T. Allen* | Was | sp | 25 | 18 | 9 | 3 | 3 | 3 | 0 | 0 | 3 | 8.7 | 2.3 | 11.2 | 7.3 | 0.9 | 3.2 | 1.22 |
| Jose Alvarado* | Ari | mr | 29 | 5 | 0 | 7 | 2 | 6 | 2 | 0 | 0 | 6.4 | 4.2 | 10.9 | 13.8 | 0.4 | 3.3 | 1.18 |
| Adbert Alzolay | ChN | cl | 29 | 2 | 4 | 0 | 2 | 0 | 0 | 0 | 2 | 8.3 | 1.5 | 10.1 | 9.2 | 1.0 | 6.2 | 1.09 |
| Ian Anderson | Atl | sp | 26 | 10 | 6 | 0 | 2 | 4 | 0 | 0 | 5 | 10.0 | 5.1 | 15.3 | 7.4 | 0.7 | 1.4 | 1.68 |
| Nick Anderson | Was | mr | 33 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 8.0 | 1.5 | 9.5 | 9.8 | 1.8 | 6.4 | 1.06 |
| Tyler Anderson* | | sp | 34 | 23 | 7 | 1 | 8 | 4 | 0 | 0 | 9 | 9.1 | 1.6 | 11.0 | 8.1 | 1.6 | 5.2 | 1.18 |
| Luarbert Arias | Col | mr | 23 | 9 | 4 | 2 | 5 | 1 | 1 | 0 | 5 | 11.9 | 2.9 | 15.2 | 9.3 | 1.3 | 3.1 | 1.64 |
| Shawn Armstrong | Ari | mr | 33 | 16 | 10 | 0 | 8 | 3 | 1 | 0 | 7 | 6.9 | 2.3 | 9.6 | 9.1 | 0.8 | 3.9 | 1.02 |
| Spencer Arrighetti | | sp | 24 | 25 | 11 | 0 | 7 | 10 | 0 | 2 | 5 | 9.0 | 3.2 | 12.6 | 8.3 | 1.6 | 2.6 | 1.36 |
| Aaron Ashby* | SD | sp | 26 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 6.3 | 2.2 | 8.4 | 9.6 | 1.0 | 4.4 | 0.94 |
| Braxton Ashcraft | Atl | sp | 24 | 14 | 4 | 0 | 5 | 2 | 1 | 0 | 2 | 10.6 | 2.1 | 13.1 | 6.8 | 0.9 | 3.3 | 1.41 |
| Graham Ashcraft | Was | sp | 26 | 19 | 5 | 0 | 8 | 8 | 0 | 0 | 3 | 8.1 | 2.1 | 10.6 | 6.4 | 1.0 | 3.1 | 1.13 |
| Pedro Avila | | sp | 27 | 2 | 1 | 0 | 3 | 1 | 0 | 0 | 0 | 7.3 | 1.5 | 10.0 | 8.9 | 0.8 | 5.8 | 0.99 |
| Anthony Banda* | Mia | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 3.6 | 12.6 | 5.4 | 1.8 | 1.5 | 1.40 |
| Tanner Banks* | Tam | mr | 32 | 4 | 1 | 1 | 2 | 0 | 0 | 0 | 1 | 6.8 | 2.0 | 9.0 | 8.9 | 1.3 | 4.4 | 0.97 |
| Scott Barlow | ChN | mr | 31 | 8 | 1 | 0 | 2 | 5 | 2 | 0 | 0 | 8.4 | 3.5 | 12.1 | 11.0 | 1.3 | 3.2 | 1.32 |
| Jaime Barria | ChN | mr | 27 | 4 | 3 | 0 | 0 | 1 | 1 | 0 | 1 | 7.9 | 1.1 | 9.0 | 6.8 | 1.5 | 6.0 | 1.00 |
| Chris Bassitt | Mil | sp | 35 | 17 | 9 | 0 | 16 | 3 | 0 | 0 | 1 | 7.0 | 1.3 | 9.0 | 8.1 | 1.0 | 6.2 | 0.93 |
| Brady Basso* | Min | sp | 26 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 12.7 | 1.8 | 15.2 | 8.5 | 1.8 | 4.7 | 1.62 |
| Mike Baumann | Bal | mr | 28 | 3 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 6.0 | 5.6 | 11.6 | 7.9 | 1.1 | 1.4 | 1.29 |
| Jarod Bayless | Phi | mr | 27 | 2 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 10.6 | 5.7 | 17.2 | 7.4 | 2.5 | 1.3 | 1.82 |
| Shane Baz | Bal | sp | 25 | 20 | 4 | 0 | 13 | 10 | 0 | 0 | 5 | 8.1 | 3.2 | 11.9 | 9.3 | 1.4 | 2.9 | 1.25 |
| Eduard Bazardo | Pit | mr | 28 | 4 | 0 | 2 | 6 | 0 | 0 | 1 | 0 | 9.5 | 2.9 | 14.0 | 9.5 | 1.1 | 3.3 | 1.38 |
| David Bednar | Tam | cl | 29 | 5 | 3 | 2 | 1 | 4 | 0 | 0 | 2 | 7.1 | 3.9 | 11.2 | 10.6 | 1.1 | 2.7 | 1.23 |
| Jalen Beeks* | LAN | mr | 30 | 8 | 2 | 2 | 8 | 2 | 0 | 1 | 2 | 9.3 | 2.6 | 12.6 | 8.3 | 1.3 | 3.2 | 1.33 |
| Clayton Beeter | NYA | sp | 25 | 10 | 2 | 0 | 4 | 7 | 0 | 0 | 0 | 9.1 | 4.5 | 14.2 | 9.0 | 1.3 | 2.0 | 1.51 |
| Brayan Bello | Mil | sp | 25 | 17 | 7 | 0 | 4 | 5 | 1 | 2 | 5 | 9.4 | 2.7 | 12.3 | 7.3 | 1.1 | 2.7 | 1.35 |
| Anthony Bender | Mil | mr | 29 | 11 | 6 | 0 | 19 | 15 | 2 | 2 | 1 | 7.6 | 1.5 | 10.2 | 8.9 | 1.4 | 5.8 | 1.02 |
| Brennan Bernardino* | NYA | mr | 32 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 7.6 | 3.8 | 11.8 | 8.5 | 1.9 | 2.3 | 1.26 |
| Jose Berrios | Tor | sp | 30 | 26 | 12 | 0 | 8 | 2 | 2 | 0 | 9 | 9.3 | 1.6 | 11.3 | 8.9 | 1.6 | 5.4 | 1.22 |
| Prelander Berroa | SF | mr | 24 | 18 | 4 | 0 | 5 | 9 | 0 | 1 | 1 | 10.6 | 9.6 | 20.8 | 9.4 | 1.7 | 1.0 | 2.25 |
| Tanner Bibee | Was | sp | 25 | 20 | 2 | 0 | 4 | 13 | 0 | 0 | 8 | 9.3 | 3.2 | 12.7 | 9.0 | 1.4 | 2.8 | 1.38 |
| Phil Bickford | Mil | mr | 28 | 5 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 9.2 | 4.0 | 13.4 | 7.7 | 1.0 | 1.9 | 1.46 |
| Osvaldo Bido | Mia | sp | 28 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 6.5 | 4.7 | 12.1 | 7.4 | 0.9 | 1.6 | 1.24 |
| Shane Bieber | Tor | sp | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.6 | 1.1 | 6.8 | 7.9 | 0.0 | 7.0 | 0.75 |
| Hunter Bigge | Sea | mr | 26 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 2 | 13.5 | 4.0 | 17.5 | 13.0 | 2.0 | 3.3 | 1.94 |
| Hayden Birdsong | Bos | sp | 22 | 23 | 5 | 0 | 9 | 7 | 0 | 0 | 4 | 7.7 | 4.5 | 13.3 | 8.5 | 1.0 | 1.9 | 1.35 |
| Mason Black | Min | sp | 24 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 12.6 | 5.4 | 18.0 | 10.8 | 3.6 | 2.0 | 2.00 |
| Ronel Blanco | Col | mr | 30 | 13 | 8 | 0 | 6 | 10 | 0 | 0 | 2 | 9.1 | 2.6 | 12.1 | 9.0 | 1.3 | 3.5 | 1.30 |
| Jonathan Bowlan | SF | sp | 27 | 17 | 3 | 1 | 2 | 4 | 0 | 1 | 2 | 10.6 | 3.3 | 14.1 | 6.4 | 1.6 | 1.9 | 1.55 |
| Joe Boyle | NYA | sp | 24 | 25 | 4 | 0 | 3 | 7 | 1 | 0 | 4 | 6.9 | 6.6 | 13.9 | 11.2 | 1.5 | 1.7 | 1.51 |
| Cody Bradford* | Tam | sp | 26 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 13.5 | 1.2 | 16.0 | 6.1 | 0.0 | 5.0 | 1.64 |
| Kyle Bradish | Bal | sp | 27 | 2 | 2 | 0 | 1 | 2 | 0 | 0 | 2 | 8.2 | 2.6 | 11.0 | 7.2 | 1.4 | 2.7 | 1.21 |
| Taj Bradley | | sp | 23 | 12 | 8 | 1 | 6 | 9 | 2 | 1 | 5 | 8.4 | 3.5 | 12.3 | 8.4 | 1.2 | 2.4 | 1.33 |
| Ryan Brasier | Pit | mr | 36 | 1 | 0 | 1 | 2 | 2 | 0 | 1 | 1 | 8.5 | 1.5 | 10.6 | 7.9 | 1.2 | 5.4 | 1.11 |
| Huascar Brazoban | NYN | mr | 34 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 11.6 | 2.3 | 13.9 | 6.2 | 3.1 | 2.7 | 1.54 |
| John Brebbia | ChA | mr | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.0 | 0.0 | 0.0 | 10.8 | 0.0 | 99.0 | 0.00 |
| Beau Brieske | StL | mr | 26 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.6 | 1.4 | 9.7 | 3.5 | 3.5 | 2.5 | 1.00 |
| Trevor Brigden | Cin | mr | 28 | 6 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 6.9 | 4.6 | 11.5 | 9.2 | 1.0 | 2.0 | 1.27 |
| Jhony Brito | ChA | sp | 26 | 18 | 7 | 0 | 5 | 3 | 1 | 0 | 3 | 9.8 | 2.3 | 12.5 | 7.8 | 1.1 | 3.4 | 1.35 |
| Kyle Brnovich | StL | sp | 26 | 18 | 7 | 0 | 7 | 3 | 0 | 0 | 3 | 8.2 | 2.0 | 10.8 | 8.8 | 1.0 | 4.4 | 1.13 |
| T.J. Brock | Phi | mr | 24 | 3 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 8.2 | 2.5 | 11.2 | 6.6 | 0.0 | 2.6 | 1.19 |
| Ben Brown | Sea | sp | 24 | 3 | 6 | 0 | 3 | 5 | 0 | 0 | 1 | 10.0 | 3.0 | 13.3 | 10.1 | 1.5 | 3.4 | 1.44 |
| Hunter Brown | Hou | sp | 25 | 25 | 15 | 0 | 9 | 4 | 0 | 1 | 4 | 8.8 | 2.9 | 12.1 | 9.8 | 1.1 | 3.4 | 1.30 |
| Zach Brzykcy | Phi | mr | 24 | 9 | 5 | 0 | 5 | 5 | 0 | 0 | 3 | 9.7 | 5.5 | 15.8 | 10.2 | 1.9 | 1.9 | 1.68 |
| Kris Bubic* | Tex | sp | 26 | 2 | 0 | 0 | 5 | 0 | 0 | 0 | 1 | 6.1 | 3.5 | 10.6 | 8.4 | 1.2 | 2.4 | 1.07 |
| Walker Buehler | LAA | sp | 29 | 13 | 2 | 1 | 3 | 2 | 0 | 0 | 0 | 7.8 | 1.8 | 9.9 | 9.4 | 1.2 | 5.3 | 1.07 |
| Aaron Bummer* | Oak | mr | 30 | 6 | 0 | 3 | 1 | 5 | 1 | 0 | 2 | 9.9 | 5.4 | 15.5 | 12.2 | 0.9 | 2.3 | 1.70 |
| Brock Burke* | SD | mr | 27 | 4 | 1 | 0 | 4 | 1 | 0 | 0 | 2 | 8.4 | 0.8 | 10.0 | 8.6 | 1.4 | 11.0 | 1.02 |
| Sean Burke | LAA | sp | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.5 | 10.5 | 18.0 | 4.5 | 3.0 | 0.4 | 2.00 |
| Corbin Burnes | Ari | sp | 29 | 36 | 10 | 0 | 7 | 7 | 2 | 0 | 4 | 7.3 | 2.7 | 10.2 | 10.3 | 0.8 | 3.8 | 1.11 |
| Mike Burrows | Tex | sp | 24 | 6 | 2 | 0 | 0 | 1 | 0 | 0 | 2 | 10.6 | 2.9 | 13.5 | 7.5 | 2.6 | 2.6 | 1.50 |
| Jose Butto | Sea | sp | 26 | 14 | 3 | 0 | 2 | 3 | 0 | 0 | 1 | 10.9 | 3.8 | 15.0 | 6.8 | 1.8 | 1.8 | 1.64 |
| Edward Cabrera | Atl | sp | 26 | 7 | 3 | 0 | 3 | 7 | 1 | 0 | 2 | 8.9 | 3.1 | 12.5 | 9.6 | 0.8 | 3.1 | 1.33 |
| Genesis Cabrera* | Tam | mr | 27 | 9 | 1 | 0 | 5 | 3 | 1 | 0 | 1 | 6.4 | 2.7 | 9.7 | 9.7 | 0.5 | 3.6 | 1.01 |
| Isaiah Campbell | Ari | mr | 26 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 9.9 | 1.5 | 11.7 | 10.2 | 2.9 | 7.0 | 1.26 |
| Griffin Canning | Cin | sp | 28 | 14 | 9 | 0 | 3 | 2 | 1 | 0 | 1 | 8.0 | 3.6 | 11.8 | 8.9 | 0.9 | 2.5 | 1.29 |
| Yennier Cano | ChN | mr | 30 | 0 | 0 | 4 | 4 | 2 | 0 | 0 | 1 | 7.3 | 1.8 | 9.6 | 8.4 | 1.0 | 4.6 | 1.01 |
| Joey Cantillo* | SF | sp | 24 | 34 | 6 | 0 | 6 | 9 | 1 | 1 | 9 | 8.6 | 5.3 | 14.2 | 9.0 | 0.9 | 1.7 | 1.54 |
| Luis Castillo | Bos | sp | 31 | 18 | 10 | 1 | 11 | 1 | 1 | 0 | 3 | 7.4 | 2.1 | 10.0 | 9.0 | 0.6 | 4.3 | 1.06 |
| Miguel Castro | Min | mr | 29 | 1 | 2 | 2 | 2 | 1 | 0 | 0 | 1 | 4.8 | 4.6 | 9.9 | 9.4 | 1.0 | 2.1 | 1.04 |
| Tim Cate* | LAN | mr | 26 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 4 | 7.8 | 3.9 | 12.1 | 5.7 | 1.1 | 1.5 | 1.30 |
| Dylan Cease | Mil | sp | 28 | 29 | 12 | 1 | 6 | 7 | 0 | 1 | 5 | 8.3 | 3.8 | 12.3 | 11.2 | 1.3 | 3.0 | 1.34 |
| Slade Cecconi | SD | sp | 25 | 14 | 9 | 0 | 16 | 1 | 0 | 0 | 5 | 7.4 | 1.6 | 9.7 | 7.2 | 1.0 | 4.5 | 1.00 |
| Andrew Chafin* | Oak | mr | 34 | 4 | 3 | 0 | 2 | 0 | 0 | 0 | 1 | 7.5 | 2.8 | 10.7 | 7.5 | 1.3 | 2.7 | 1.14 |
| Chandler Champlain | | sp | 24 | 14 | 1 | 1 | 2 | 4 | 1 | 0 | 2 | 10.1 | 3.2 | 13.6 | 6.7 | 1.3 | 2.1 | 1.48 |
| Aroldis Chapman* | LAA | mr | 36 | 12 | 0 | 2 | 1 | 4 | 1 | 0 | 2 | 4.9 | 5.6 | 10.6 | 14.0 | 1.3 | 2.5 | 1.16 |
| Jesse Chavez | ChA | mr | 40 | 6 | 5 | 1 | 2 | 1 | 0 | 0 | 0 | 9.6 | 3.4 | 13.2 | 8.2 | 2.4 | 2.4 | 1.45 |
| Aaron Civale | Min | sp | 29 | 6 | 6 | 0 | 6 | 2 | 1 | 0 | 4 | 9.0 | 2.0 | 11.3 | 8.1 | 1.3 | 4.0 | 1.22 |
| Emmanuel Clase | Sea | cl | 26 | 5 | 3 | 0 | 2 | 4 | 0 | 1 | 2 | 7.9 | 1.9 | 10.1 | 11.9 | 0.1 | 6.2 | 1.10 |
| Garrett Cleavinger* | Ari | mr | 30 | 9 | 2 | 0 | 4 | 3 | 0 | 0 | 1 | 7.2 | 3.7 | 11.3 | 12.8 | 1.2 | 3.5 | 1.21 |
| Alex Cobb | SD | sp | 36 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 10.4 | 1.1 | 11.5 | 7.3 | 0.8 | 6.5 | 1.28 |
| Isaac Coffey | Cin | sp | 24 | 32 | 5 | 0 | 15 | 4 | 0 | 0 | 5 | 7.1 | 2.5 | 10.5 | 7.5 | 0.8 | 2.9 | 1.07 |
| Gerrit Cole | Oak | sp | 33 | 14 | 3 | 0 | 3 | 1 | 1 | 0 | 3 | 8.3 | 2.6 | 11.1 | 9.8 | 1.3 | 3.8 | 1.20 |
| Luis Contreras | StL | mr | 28 | 4 | 3 | 1 | 4 | 3 | 0 | 0 | 1 | 8.1 | 3.4 | 12.4 | 9.2 | 1.5 | 2.7 | 1.29 |
| Roansy Contreras | Det | sp | 24 | 38 | 7 | 0 | 5 | 8 | 1 | 1 | 4 | 7.4 | 2.5 | 10.1 | 9.3 | 0.8 | 3.8 | 1.09 |
| Connor Cooke | Pit | mr | 24 | 15 | 3 | 2 | 7 | 12 | 0 | 0 | 3 | 9.5 | 3.8 | 13.8 | 10.3 | 1.4 | 2.7 | 1.47 |
| Nestor Cortes* | | sp | 29 | 16 | 6 | 1 | 5 | 4 | 2 | 0 | 9 | 7.3 | 1.8 | 9.3 | 8.1 | 0.9 | 4.4 | 1.01 |
| Tom Cosgrove* | | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 8.3 | 3.1 | 11.4 | 7.3 | 2.1 | 2.3 | 1.27 |
| Danny Coulombe* | Det | mr | 34 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 13.1 | 0.0 | 13.1 | 16.5 | 0.0 | 99.0 | 1.45 |
| Jake Cousins | Mil | mr | 29 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 3.4 | 6.8 | 11.8 | 10.1 | 1.7 | 1.5 | 1.13 |
| Austin Cox* | ChA | sp | 27 | 3 | 3 | 0 | 0 | 1 | 0 | 0 | 2 | 8.3 | 2.8 | 11.0 | 7.7 | 1.2 | 2.8 | 1.22 |
| Kutter Crawford | Det | sp | 28 | 12 | 5 | 0 | 4 | 3 | 0 | 0 | 2 | 9.3 | 1.8 | 11.4 | 8.2 | 1.6 | 4.6 | 1.23 |
| Garrett Crochet* | | mr | 25 | 5 | 0 | 0 | 3 | 3 | 0 | 0 | 3 | 7.9 | 4.0 | 12.3 | 10.3 | 0.9 | 2.6 | 1.32 |
| Declan Cronin | | mr | 26 | 9 | 1 | 1 | 6 | 5 | 0 | 1 | 2 | 11.9 | 2.8 | 15.6 | 6.8 | 1.5 | 2.4 | 1.63 |
| Hans Crouse | Sea | sp | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 6.8 | 13.5 | 13.5 | 6.8 | 2.0 | 1.50 |
| Fernando Cruz | | mr | 34 | 2 | 1 | 1 | 3 | 2 | 0 | 0 | 1 | 5.3 | 3.4 | 10.1 | 13.0 | 0.5 | 3.9 | 0.96 |
| Hagen Danner | Cin | mr | 25 | 3 | 1 | 0 | 1 | 2 | 0 | 0 | 1 | 8.0 | 3.7 | 11.9 | 8.2 | 0.3 | 2.2 | 1.29 |
| Yu Darvish | | sp | 37 | 13 | 6 | 0 | 10 | 0 | 1 | 0 | 5 | 6.8 | 1.3 | 8.9 | 8.4 | 1.0 | 6.4 | 0.89 |
| Enyel De Los Santos | Mil | mr | 28 | 8 | 2 | 0 | 2 | 1 | 0 | 1 | 2 | 7.8 | 3.3 | 11.5 | 8.5 | 1.8 | 2.5 | 1.24 |
| Jacob deGrom | Cle | sp | 36 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 2.9 | 6.9 | 12.8 | 0.0 | 4.3 | 0.76 |
| Reid Detmers* | | sp | 24 | 26 | 4 | 1 | 9 | 4 | 0 | 0 | 3 | 8.0 | 2.2 | 10.6 | 9.0 | 1.4 | 4.1 | 1.13 |
| Chris Devenski | ChN | mr | 33 | 19 | 4 | 0 | 6 | 0 | 0 | 0 | 1 | 6.7 | 1.5 | 8.7 | 8.6 | 0.8 | 5.6 | 0.92 |
| Alexis Diaz | | cl | 27 | 8 | 1 | 0 | 13 | 6 | 0 | 0 | 1 | 5.5 | 3.2 | 10.7 | 11.7 | 0.5 | 3.7 | 0.97 |
| Edwin Diaz | | cl | 30 | 5 | 2 | 0 | 5 | 3 | 2 | 0 | 2 | 7.1 | 3.3 | 11.2 | 13.0 | 0.8 | 4.0 | 1.15 |
| Miguel Diaz | SD | mr | 29 | 2 | 0 | 0 | 2 | 4 | 0 | 0 | 1 | 11.0 | 3.5 | 15.0 | 8.9 | 1.2 | 2.5 | 1.62 |
| Yilber Diaz | | sp | 23 | 12 | 1 | 0 | 4 | 5 | 1 | 0 | 2 | 9.3 | 3.5 | 13.6 | 8.0 | 1.9 | 2.3 | 1.43 |
| Jake Diekman* | SD | mr | 37 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 9.0 | 9.0 | 18.0 | 12.0 | 3.0 | 1.3 | 2.00 |
| Hunter Dobbins | Sea | sp | 24 | 8 | 3 | 0 | 3 | 1 | 0 | 0 | 3 | 10.4 | 1.4 | 12.3 | 6.6 | 1.4 | 4.8 | 1.31 |
| Seranthony Dominguez | Was | mr | 29 | 8 | 1 | 1 | 1 | 2 | 0 | 0 | 2 | 7.8 | 4.4 | 12.3 | 10.0 | 1.0 | 2.3 | 1.35 |
| Camilo Doval | Oak | cl | 26 | 8 | 1 | 0 | 2 | 9 | 1 | 1 | 2 | 8.2 | 2.9 | 11.4 | 11.4 | 0.7 | 4.0 | 1.23 |
| Shawn Dubin | Was | sp | 28 | 11 | 3 | 0 | 4 | 1 | 0 | 1 | 0 | 8.1 | 2.8 | 11.4 | 9.3 | 1.3 | 3.4 | 1.21 |
| Dane Dunning | LAA | sp | 29 | 10 | 5 | 0 | 11 | 10 | 0 | 1 | 8 | 9.3 | 2.8 | 12.8 | 7.1 | 1.3 | 2.5 | 1.34 |
| Jhoan Duran | Sea | cl | 26 | 6 | 4 | 0 | 5 | 3 | 0 | 0 | 1 | 7.7 | 2.2 | 10.7 | 13.6 | 0.3 | 6.2 | 1.10 |
| Jake Eder* | Tex | sp | 25 | 16 | 1 | 0 | 5 | 3 | 0 | 0 | 4 | 10.2 | 5.0 | 16.0 | 9.2 | 2.5 | 1.8 | 1.69 |
| Scott Effross | Det | mr | 30 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 5.3 | 1.6 | 6.9 | 7.2 | 0.3 | 4.6 | 0.77 |
| Zach Eflin | | sp | 30 | 21 | 5 | 0 | 5 | 3 | 1 | 0 | 4 | 10.7 | 1.3 | 12.3 | 10.0 | 0.7 | 7.7 | 1.34 |
| Brandon Eisert* | Det | mr | 26 | 10 | 4 | 0 | 1 | 1 | 1 | 0 | 1 | 8.1 | 2.0 | 10.2 | 9.1 | 1.1 | 4.6 | 1.12 |
| Bryce Elder | | sp | 25 | 19 | 7 | 2 | 10 | 13 | 1 | 0 | 9 | 8.4 | 3.0 | 11.8 | 7.4 | 0.8 | 2.5 | 1.26 |
| Fraser Ellard* | Sea | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 18.0 | 27.0 | 18.0 | 0.0 | 1.0 | 3.00 |
| Nic Enright | | mr | 27 | 4 | 0 | 2 | 1 | 2 | 0 | 0 | 1 | 9.8 | 2.3 | 12.5 | 12.5 | 0.8 | 5.3 | 1.35 |
| Nathan Eovaldi | Oak | sp | 34 | 12 | 4 | 0 | 4 | 4 | 0 | 0 | 2 | 8.0 | 2.1 | 10.4 | 8.9 | 1.1 | 4.2 | 1.13 |
| Lucas Erceg | LAN | mr | 29 | 0 | 0 | 1 | 3 | 2 | 0 | 1 | 1 | 6.5 | 7.9 | 15.5 | 9.0 | 1.8 | 1.1 | 1.60 |
| Joey Estes | Mia | sp | 22 | 1 | 0 | 1 | 4 | 0 | 0 | 0 | 2 | 11.4 | 2.8 | 15.1 | 6.8 | 2.6 | 2.4 | 1.58 |
| Carlos Estevez | Tor | mr | 31 | 4 | 3 | 0 | 2 | 5 | 1 | 0 | 2 | 8.7 | 4.8 | 13.8 | 10.7 | 1.3 | 2.2 | 1.50 |
| Jeremiah Estrada | Sea | mr | 25 | 3 | 1 | 2 | 1 | 3 | 1 | 0 | 5 | 8.8 | 6.0 | 14.9 | 11.1 | 1.3 | 1.9 | 1.64 |
| Alex Faedo | Phi | sp | 28 | 18 | 7 | 1 | 5 | 1 | 0 | 0 | 9 | 9.7 | 2.7 | 12.8 | 8.2 | 1.3 | 3.0 | 1.39 |
| Pete Fairbanks | ChN | cl | 30 | 4 | 2 | 0 | 3 | 5 | 0 | 0 | 2 | 8.5 | 3.8 | 13.2 | 15.1 | 0.9 | 4.0 | 1.36 |
| Bailey Falter* | KC | sp | 27 | 8 | 2 | 0 | 3 | 2 | 0 | 0 | 2 | 9.6 | 2.0 | 12.1 | 8.3 | 0.9 | 4.1 | 1.29 |
| Calvin Faucher | Hou | mr | 28 | 0 | 1 | 0 | 1 | 4 | 0 | 0 | 2 | 12.5 | 6.2 | 19.2 | 7.3 | 2.6 | 1.2 | 2.08 |
| Erick Fedde | Hou | sp | 31 | 8 | 1 | 0 | 2 | 1 | 0 | 0 | 1 | 14.3 | 2.9 | 17.7 | 8.9 | 2.7 | 3.1 | 1.92 |
| Caleb Ferguson* | Tor | mr | 27 | 4 | 3 | 0 | 5 | 1 | 0 | 0 | 0 | 11.0 | 2.9 | 15.1 | 11.2 | 1.7 | 3.9 | 1.54 |
| Ryan Fernandez | SD | mr | 26 | 3 | 3 | 0 | 1 | 1 | 0 | 0 | 2 | 7.8 | 3.0 | 11.0 | 8.8 | 2.2 | 2.9 | 1.20 |
| Jose A. Ferrer* | Mia | mr | 24 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 10.2 | 3.7 | 14.9 | 9.3 | 0.9 | 2.5 | 1.55 |
| David Festa | | sp | 24 | 25 | 7 | 0 | 2 | 5 | 0 | 1 | 6 | 8.3 | 3.6 | 12.1 | 8.5 | 1.0 | 2.4 | 1.32 |
| J.P. Feyereisen | Pit | mr | 31 | 2 | 1 | 0 | 2 | 1 | 0 | 0 | 1 | 10.7 | 3.7 | 14.9 | 10.0 | 1.9 | 2.7 | 1.60 |
| Kyle Finnegan | NYN | cl | 32 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 6.9 | 2.4 | 9.4 | 8.9 | 2.1 | 3.6 | 1.03 |
| Richard Fitts | | sp | 24 | 13 | 7 | 0 | 5 | 2 | 1 | 0 | 10 | 8.2 | 1.8 | 10.3 | 6.6 | 0.8 | 3.7 | 1.11 |
| Jack Flaherty | Hou | sp | 28 | 21 | 4 | 0 | 12 | 10 | 0 | 1 | 7 | 7.0 | 3.5 | 11.0 | 8.0 | 0.9 | 2.3 | 1.16 |
| Josh Fleming* | Tam | mr | 28 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 10.4 | 1.0 | 11.4 | 4.2 | 0.0 | 4.0 | 1.27 |
| Wilmer Flores | ChN | sp | 23 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.6 | 1.8 | 7.2 | 9.0 | 0.0 | 5.0 | 0.60 |
| Dylan Floro | Was | mr | 33 | 2 | 1 | 2 | 1 | 0 | 1 | 0 | 0 | 9.9 | 1.3 | 11.4 | 9.3 | 0.5 | 7.2 | 1.24 |
| Mason Fluharty* | Phi | mr | 22 | 18 | 1 | 4 | 3 | 4 | 0 | 0 | 4 | 9.9 | 4.1 | 14.2 | 9.1 | 1.4 | 2.2 | 1.55 |
| Jason Foley | Oak | mr | 28 | 6 | 0 | 1 | 2 | 0 | 1 | 0 | 1 | 10.4 | 2.3 | 13.1 | 6.1 | 1.6 | 2.6 | 1.41 |
| J.P. France | KC | sp | 29 | 6 | 0 | 2 | 0 | 0 | 1 | 0 | 2 | 10.4 | 4.0 | 14.4 | 9.8 | 1.0 | 2.5 | 1.60 |
| Bowden Francis | Tex | sp | 28 | 3 | 2 | 0 | 3 | 2 | 0 | 0 | 0 | 6.5 | 2.1 | 9.3 | 8.4 | 1.4 | 4.0 | 0.96 |
| Kyle Freeland* | Min | sp | 31 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.0 | 1.8 | 12.6 | 5.4 | 0.0 | 3.0 | 1.20 |
| Luis Frias | Bal | mr | 26 | 18 | 5 | 0 | 1 | 4 | 1 | 0 | 4 | 10.4 | 4.9 | 15.3 | 9.0 | 1.1 | 1.8 | 1.70 |
| Max Fried* | Ari | sp | 30 | 20 | 10 | 0 | 9 | 10 | 0 | 2 | 2 | 7.2 | 1.6 | 9.1 | 9.0 | 0.5 | 5.6 | 0.98 |
| Kody Funderburk* | ChN | mr | 27 | 14 | 4 | 0 | 3 | 1 | 0 | 0 | 3 | 8.3 | 3.5 | 12.3 | 9.6 | 1.2 | 2.7 | 1.32 |
| Hunter Gaddis | Bos | sp | 26 | 14 | 2 | 0 | 19 | 9 | 0 | 0 | 5 | 8.1 | 2.9 | 12.0 | 8.3 | 1.1 | 2.9 | 1.22 |
| Giovanny Gallegos | | mr | 32 | 3 | 0 | 0 | 1 | 4 | 0 | 0 | 3 | 6.6 | 2.1 | 8.9 | 10.3 | 1.4 | 5.0 | 0.96 |
| Zac Gallen | | sp | 28 | 15 | 9 | 0 | 7 | 7 | 0 | 0 | 2 | 6.4 | 2.4 | 9.1 | 7.7 | 0.8 | 3.3 | 0.98 |
| Robert Garcia* | Was | mr | 28 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 7.9 | 3.8 | 11.7 | 8.4 | 1.3 | 2.2 | 1.30 |
| Yimi Garcia | | mr | 33 | 5 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 8.0 | 3.1 | 11.7 | 10.7 | 1.0 | 3.5 | 1.23 |
| Braxton Garrett* | Mia | sp | 26 | 11 | 1 | 0 | 3 | 2 | 1 | 0 | 2 | 10.2 | 1.2 | 11.9 | 5.2 | 1.4 | 4.3 | 1.27 |
| Reed Garrett | NYN | mr | 31 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 13.5 | 3.4 | 16.9 | 8.4 | 1.7 | 2.5 | 1.88 |
| Robert Gasser* | Atl | sp | 25 | 4 | 0 | 1 | 3 | 5 | 0 | 0 | 2 | 10.9 | 2.8 | 14.4 | 9.8 | 1.8 | 3.5 | 1.51 |
| Chris Gau | Oak | mr | 27 | 10 | 3 | 0 | 7 | 5 | 0 | 0 | 1 | 7.5 | 2.7 | 10.8 | 8.2 | 0.7 | 3.0 | 1.13 |
| Kevin Gausman | | sp | 33 | 34 | 8 | 1 | 4 | 3 | 0 | 0 | 2 | 8.1 | 1.9 | 10.1 | 9.9 | 1.4 | 5.3 | 1.10 |
| Domingo German | Pit | sp | 31 | 31 | 9 | 0 | 8 | 2 | 0 | 0 | 8 | 9.0 | 2.2 | 11.5 | 8.5 | 1.3 | 3.9 | 1.24 |
| Kyle Gibson | Min | sp | 36 | 9 | 2 | 0 | 5 | 2 | 0 | 1 | 8 | 9.3 | 3.1 | 12.6 | 6.0 | 0.8 | 2.0 | 1.37 |
| Luis Gil | | sp | 26 | 18 | 5 | 0 | 3 | 7 | 3 | 0 | 3 | 7.3 | 5.2 | 12.7 | 10.7 | 1.2 | 2.1 | 1.38 |
| Logan Gilbert | Ari | sp | 27 | 30 | 5 | 0 | 8 | 4 | 3 | 0 | 6 | 7.9 | 2.3 | 10.5 | 8.7 | 0.8 | 3.8 | 1.14 |
| Keagan Gillies | Cin | mr | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 13.5 | 0.0 | 13.5 | 9.0 | 4.5 | 99.0 | 1.50 |
| Kevin Ginkel | | mr | 30 | 4 | 2 | 0 | 1 | 4 | 0 | 0 | 3 | 5.9 | 3.9 | 9.9 | 10.2 | 1.0 | 2.6 | 1.09 |
| J.T. Ginn | Pit | sp | 25 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.3 | 2.9 | 13.2 | 9.2 | 1.7 | 3.2 | 1.47 |
| Tyler Glasnow | Sea | sp | 30 | 23 | 4 | 0 | 0 | 7 | 0 | 0 | 4 | 7.1 | 2.3 | 9.4 | 11.1 | 1.3 | 4.9 | 1.04 |
| Woo-suk Go | Mil | mr | 25 | 2 | 1 | 0 | 3 | 1 | 1 | 0 | 0 | 7.6 | 3.3 | 11.6 | 9.6 | 2.0 | 2.9 | 1.21 |
| Yoendrys Gomez | NYA | sp | 24 | 3 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 12.1 | 3.3 | 15.8 | 8.4 | 2.8 | 2.6 | 1.71 |
| Marco Gonzales* | ChA | sp | 32 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 14.5 | 2.8 | 17.3 | 5.5 | 1.4 | 2.0 | 1.92 |
| Colton Gordon* | Phi | sp | 25 | 9 | 0 | 0 | 2 | 3 | 0 | 0 | 1 | 8.5 | 2.8 | 11.7 | 6.0 | 0.6 | 2.1 | 1.26 |
| MacKenzie Gore* | NYN | sp | 25 | 15 | 11 | 2 | 2 | 12 | 2 | 1 | 2 | 6.4 | 3.1 | 9.6 | 10.0 | 1.1 | 3.2 | 1.05 |
| Anthony Gose* | Hou | mr | 33 | 4 | 3 | 0 | 4 | 4 | 1 | 1 | 3 | 5.7 | 5.2 | 11.5 | 11.5 | 1.6 | 2.2 | 1.21 |
| Gordon Graceffo | | sp | 24 | 7 | 7 | 1 | 3 | 8 | 1 | 0 | 2 | 10.0 | 3.2 | 13.6 | 6.0 | 0.9 | 1.9 | 1.48 |
| Brusdar Graterol | Bal | mr | 25 | 2 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 7.0 | 1.4 | 8.4 | 8.8 | 0.9 | 6.3 | 0.93 |
| Jon Gray | Oak | sp | 32 | 19 | 9 | 0 | 15 | 3 | 2 | 0 | 0 | 7.4 | 2.4 | 10.5 | 8.8 | 1.3 | 3.7 | 1.08 |
| Sonny Gray | | sp | 34 | 17 | 4 | 0 | 7 | 5 | 0 | 0 | 1 | 9.1 | 2.3 | 11.8 | 7.6 | 1.1 | 3.3 | 1.27 |
| Chad Green | ChN | mr | 33 | 4 | 2 | 0 | 2 | 3 | 1 | 0 | 0 | 6.3 | 2.0 | 8.5 | 10.8 | 0.6 | 5.5 | 0.92 |
| Hunter Greene | Col | sp | 24 | 26 | 5 | 0 | 6 | 4 | 0 | 1 | 2 | 9.0 | 3.7 | 13.1 | 12.8 | 1.2 | 3.5 | 1.41 |
| Michael Grove | | sp | 27 | 3 | 1 | 0 | 2 | 5 | 0 | 0 | 1 | 7.6 | 2.4 | 10.3 | 9.6 | 0.7 | 4.0 | 1.11 |
| Luis Guerrero | Tor | mr | 23 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 10.3 | 3.9 | 14.6 | 8.6 | 0.0 | 2.2 | 1.57 |
| Tyson Guerrero* | Sea | sp | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 0.0 | 3.9 | 11.6 | 1.3 | 99.0 | 0.43 |
| Josh Hader* | | cl | 30 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 2 | 5.7 | 2.7 | 8.7 | 13.0 | 0.3 | 4.8 | 0.93 |
| Justin Hagenman | Oak | mr | 27 | 16 | 2 | 1 | 1 | 0 | 0 | 0 | 1 | 9.9 | 3.4 | 13.4 | 6.5 | 1.1 | 1.9 | 1.48 |
| DL Hall* | Bal | mr | 25 | 17 | 7 | 0 | 5 | 6 | 1 | 0 | 1 | 7.6 | 4.7 | 12.7 | 12.4 | 1.3 | 2.6 | 1.37 |
| Ian Hamilton | Tex | mr | 29 | 9 | 0 | 0 | 4 | 0 | 0 | 0 | 1 | 5.6 | 2.2 | 8.3 | 11.4 | 0.9 | 5.2 | 0.87 |
| Emerson Hancock | Sea | sp | 25 | 25 | 15 | 0 | 11 | 6 | 3 | 0 | 3 | 9.9 | 2.2 | 12.6 | 8.2 | 0.8 | 3.7 | 1.34 |
| Hayden Harris* | | mr | 25 | 3 | 2 | 1 | 2 | 3 | 0 | 0 | 2 | 9.3 | 4.1 | 13.9 | 8.5 | 0.3 | 2.1 | 1.49 |
| Kyle Harrison* | Atl | sp | 22 | 18 | 6 | 1 | 3 | 0 | 1 | 0 | 2 | 8.4 | 5.2 | 13.9 | 9.9 | 1.3 | 1.9 | 1.52 |
| Grant Hartwig | NYN | mr | 26 | 2 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 8.2 | 7.0 | 16.4 | 7.6 | 0.6 | 1.1 | 1.70 |
| Hunter Harvey | | mr | 29 | 2 | 1 | 0 | 0 | 3 | 2 | 0 | 2 | 6.5 | 1.6 | 8.2 | 7.5 | 0.5 | 4.6 | 0.91 |
| Andrew Heaney* | KC | sp | 33 | 9 | 1 | 0 | 7 | 2 | 0 | 0 | 5 | 9.2 | 2.2 | 12.1 | 10.0 | 1.7 | 4.5 | 1.27 |
| Ryan Helsley | | cl | 29 | 3 | 0 | 1 | 0 | 4 | 0 | 0 | 2 | 7.7 | 2.3 | 10.0 | 11.6 | 1.2 | 5.1 | 1.11 |
| Markevian Hence | SF | sp | 21 | 27 | 4 | 1 | 6 | 6 | 0 | 0 | 6 | 9.4 | 2.8 | 12.6 | 6.5 | 1.3 | 2.3 | 1.36 |
| Ryan Hennen* | Det | mr | 26 | 3 | 2 | 1 | 5 | 1 | 1 | 0 | 2 | 7.7 | 1.5 | 10.0 | 7.3 | 1.0 | 4.9 | 1.02 |
| Ronny Henriquez | Was | mr | 24 | 10 | 5 | 0 | 5 | 1 | 0 | 0 | 5 | 9.7 | 2.8 | 13.1 | 6.4 | 1.1 | 2.3 | 1.38 |
| Cole Henry | Pit | sp | 24 | 16 | 3 | 0 | 9 | 7 | 0 | 0 | 6 | 8.8 | 2.9 | 12.5 | 9.2 | 1.1 | 3.2 | 1.30 |
| Tommy Henry* | LAA | sp | 26 | 4 | 2 | 0 | 4 | 2 | 1 | 0 | 3 | 8.0 | 2.3 | 10.8 | 7.2 | 0.8 | 3.1 | 1.15 |
| Sam Hentges* | Tex | mr | 27 | 3 | 1 | 2 | 0 | 2 | 0 | 0 | 2 | 7.4 | 2.0 | 9.3 | 8.8 | 2.0 | 4.5 | 1.04 |
| Carlos Hernandez | Tex | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.4 | 0.0 | 7.4 | 0.0 | 2.5 | 0.0 | 0.82 |
| Daysbel Hernandez | NYN | mr | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 20.3 | 13.5 | 33.8 | 13.5 | 0.0 | 1.0 | 3.75 |
| Jakob Hernandez* | Oak | mr | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12.6 | 3.6 | 16.2 | 10.8 | 1.8 | 3.0 | 1.80 |
| Jose Hernandez* | Was | mr | 26 | 4 | 1 | 1 | 1 | 1 | 2 | 0 | 1 | 7.6 | 4.3 | 12.2 | 11.5 | 0.4 | 2.7 | 1.32 |
| Tim Herrin* | Sea | mr | 27 | 8 | 4 | 2 | 0 | 11 | 0 | 1 | 6 | 6.7 | 3.2 | 9.9 | 9.4 | 1.2 | 2.9 | 1.10 |
| Jordan Hicks | SF | mr | 27 | 17 | 2 | 3 | 8 | 13 | 0 | 2 | 3 | 9.6 | 5.6 | 16.0 | 10.8 | 1.3 | 1.9 | 1.70 |
| Porter Hodge | Was | mr | 23 | 17 | 5 | 0 | 4 | 3 | 1 | 0 | 4 | 7.9 | 4.4 | 12.8 | 8.0 | 1.2 | 1.8 | 1.37 |
| Jeff Hoffman | | mr | 31 | 12 | 3 | 0 | 3 | 5 | 0 | 0 | 0 | 10.2 | 3.7 | 14.3 | 12.3 | 1.3 | 3.3 | 1.54 |
| Gunnar Hoglund | Oak | sp | 24 | 10 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 10.2 | 2.3 | 12.8 | 7.2 | 1.0 | 3.1 | 1.39 |
| Colin Holderman | Phi | mr | 28 | 7 | 3 | 1 | 7 | 8 | 0 | 0 | 3 | 7.4 | 2.9 | 11.0 | 9.8 | 1.3 | 3.4 | 1.14 |
| Grant Holman | KC | mr | 24 | 3 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 10.6 | 2.9 | 13.8 | 9.1 | 1.2 | 3.2 | 1.49 |
| Clay Holmes | Oak | cl | 31 | 1 | 2 | 0 | 4 | 3 | 0 | 0 | 3 | 6.9 | 2.4 | 9.8 | 11.2 | 1.1 | 4.7 | 1.03 |
| Grant Holmes | Mia | mr | 28 | 6 | 4 | 0 | 1 | 3 | 0 | 0 | 1 | 6.8 | 2.9 | 9.9 | 9.9 | 1.1 | 3.5 | 1.08 |
| Tyler Holton* | | mr | 28 | 8 | 2 | 0 | 4 | 7 | 0 | 0 | 2 | 7.3 | 1.6 | 9.3 | 7.7 | 0.8 | 4.7 | 0.99 |
| Brent Honeywell | Col | mr | 29 | 2 | 3 | 0 | 2 | 1 | 0 | 0 | 2 | 8.2 | 2.7 | 11.3 | 5.7 | 0.8 | 2.1 | 1.22 |
| Tanner Houck | LAN | sp | 28 | 24 | 8 | 0 | 13 | 3 | 1 | 0 | 6 | 8.5 | 3.2 | 12.4 | 9.2 | 1.5 | 2.9 | 1.30 |
| Spencer Howard | | sp | 27 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 9.6 | 3.9 | 13.8 | 10.5 | 2.2 | 2.7 | 1.50 |
| Bryan Hudson* | Col | mr | 27 | 4 | 3 | 2 | 3 | 4 | 0 | 0 | 3 | 12.1 | 3.8 | 16.4 | 11.0 | 1.7 | 2.9 | 1.76 |
| Daniel Hudson | | mr | 37 | 4 | 0 | 0 | 1 | 3 | 0 | 1 | 0 | 8.0 | 3.0 | 11.2 | 9.5 | 1.9 | 3.1 | 1.23 |
| Brandon Hughes* | NYN | mr | 28 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.9 | 2.6 | 6.9 | 7.3 | 0.9 | 2.8 | 0.71 |
| Kyle Hurt | Bos | sp | 26 | 6 | 0 | 0 | 1 | 3 | 0 | 0 | 2 | 7.3 | 3.3 | 10.9 | 10.9 | 1.9 | 3.3 | 1.18 |
| Brant Hurter* | ChN | sp | 25 | 33 | 14 | 6 | 9 | 14 | 1 | 1 | 5 | 9.0 | 2.0 | 11.4 | 6.7 | 1.1 | 3.3 | 1.22 |
| Raisel Iglesias | | cl | 34 | 3 | 2 | 4 | 1 | 1 | 1 | 0 | 2 | 8.4 | 1.4 | 9.9 | 11.0 | 0.5 | 7.9 | 1.08 |
| Shota Imanaga* | SD | sp | 30 | 16 | 7 | 0 | 10 | 0 | 1 | 0 | 3 | 7.9 | 1.9 | 10.3 | 9.2 | 1.2 | 4.8 | 1.09 |
| Jairo Iriarte | Col | sp | 22 | 4 | 4 | 0 | 8 | 1 | 0 | 0 | 0 | 13.0 | 4.0 | 18.9 | 9.4 | 2.3 | 2.3 | 1.90 |
| Cole Irvin* | ChA | sp | 30 | 9 | 7 | 0 | 10 | 4 | 1 | 0 | 4 | 10.6 | 1.4 | 12.5 | 6.6 | 1.6 | 4.8 | 1.33 |
| Jake Irvin | | sp | 27 | 9 | 5 | 0 | 11 | 5 | 0 | 0 | 6 | 7.7 | 3.2 | 11.7 | 7.2 | 1.6 | 2.2 | 1.21 |
| Jay Jackson | Mia | mr | 36 | 9 | 2 | 0 | 1 | 0 | 1 | 0 | 3 | 9.5 | 3.3 | 13.0 | 10.7 | 2.1 | 3.2 | 1.42 |
| Alek Jacob | Pit | mr | 26 | 2 | 2 | 0 | 3 | 1 | 0 | 0 | 0 | 5.8 | 1.3 | 8.4 | 6.6 | 0.9 | 5.0 | 0.79 |
| Kenley Jansen | | cl | 36 | 5 | 2 | 2 | 3 | 0 | 1 | 1 | 1 | 10.4 | 4.0 | 14.9 | 11.3 | 2.3 | 2.8 | 1.60 |
| Bryce Jarvis | LAA | sp | 26 | 6 | 1 | 0 | 0 | 7 | 0 | 0 | 4 | 7.3 | 2.6 | 10.0 | 6.2 | 1.8 | 2.4 | 1.11 |
| Cristian Javier | Min | sp | 27 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 7.8 | 3.3 | 11.0 | 10.5 | 1.3 | 3.2 | 1.22 |
| Griffin Jax | Min | mr | 29 | 3 | 2 | 3 | 7 | 0 | 0 | 0 | 0 | 8.0 | 2.0 | 11.2 | 8.5 | 0.5 | 4.3 | 1.11 |
| Joe Jimenez | NYN | mr | 29 | 15 | 6 | 0 | 4 | 1 | 0 | 0 | 2 | 6.8 | 3.3 | 10.7 | 11.2 | 1.6 | 3.4 | 1.13 |
| Jackson Jobe | SF | sp | 21 | 19 | 3 | 0 | 5 | 3 | 0 | 0 | 9 | 9.9 | 3.4 | 13.7 | 7.4 | 1.4 | 2.2 | 1.48 |
| Pierce Johnson | Mil | mr | 33 | 3 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 7.0 | 3.8 | 11.1 | 11.3 | 1.6 | 3.0 | 1.20 |
| Seth Johnson | Phi | sp | 25 | 17 | 1 | 1 | 5 | 5 | 1 | 0 | 1 | 8.3 | 3.9 | 12.7 | 9.3 | 1.2 | 2.4 | 1.36 |
| Jared Jones | Bos | sp | 22 | 23 | 6 | 0 | 6 | 3 | 0 | 0 | 4 | 7.8 | 3.6 | 11.8 | 7.9 | 0.9 | 2.2 | 1.27 |
| Hayden Juenger | Hou | mr | 23 | 7 | 6 | 0 | 4 | 3 | 0 | 0 | 1 | 7.5 | 4.0 | 12.0 | 8.1 | 0.8 | 2.0 | 1.28 |
| Jakob Junis | Det | mr | 31 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 9.0 | 0.8 | 10.2 | 5.9 | 1.6 | 7.5 | 1.09 |
| Tommy Kahnle | Oak | mr | 34 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 8.3 | 2.1 | 10.4 | 12.5 | 1.6 | 6.0 | 1.15 |
| Mitch Keller | | sp | 28 | 28 | 17 | 0 | 14 | 3 | 1 | 1 | 10 | 8.4 | 2.4 | 11.4 | 8.2 | 0.9 | 3.4 | 1.20 |
| Antoine Kelly* | Atl | mr | 24 | 2 | 0 | 0 | 2 | 4 | 0 | 0 | 0 | 10.8 | 4.7 | 16.9 | 10.1 | 0.7 | 2.1 | 1.72 |
| Joe Kelly | LAA | mr | 36 | 2 | 2 | 0 | 2 | 0 | 0 | 0 | 1 | 8.7 | 4.3 | 14.0 | 10.1 | 1.0 | 2.3 | 1.45 |
| Kevin Kelly | | mr | 26 | 5 | 0 | 4 | 11 | 1 | 0 | 0 | 2 | 8.5 | 2.1 | 11.9 | 9.4 | 0.2 | 4.6 | 1.17 |
| Merrill Kelly | Det | sp | 35 | 11 | 2 | 0 | 2 | 2 | 1 | 1 | 3 | 7.4 | 1.6 | 9.2 | 8.3 | 0.8 | 5.1 | 1.00 |
| Michael Kelly | Bal | mr | 31 | 5 | 5 | 0 | 1 | 3 | 0 | 0 | 1 | 8.9 | 6.7 | 15.9 | 9.2 | 1.0 | 1.4 | 1.73 |
| Zack Kelly | Bal | mr | 29 | 7 | 1 | 0 | 4 | 6 | 0 | 0 | 3 | 7.9 | 6.8 | 15.8 | 8.7 | 1.9 | 1.3 | 1.64 |
| Orion Kerkering | Bos | mr | 23 | 10 | 2 | 0 | 3 | 8 | 0 | 0 | 1 | 8.7 | 1.8 | 10.8 | 10.8 | 1.3 | 6.1 | 1.17 |
| Ray Kerr* | LAA | mr | 29 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 7.7 | 5.1 | 14.1 | 14.1 | 0.0 | 2.8 | 1.43 |
| Brett Kerry | NYA | sp | 25 | 12 | 0 | 0 | 2 | 8 | 0 | 0 | 6 | 11.8 | 3.3 | 15.2 | 6.1 | 2.1 | 1.9 | 1.67 |
| Clayton Kershaw* | LAA | sp | 36 | 2 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 7.9 | 1.1 | 9.0 | 11.6 | 1.1 | 10.6 | 1.00 |
| Yusei Kikuchi* | NYN | sp | 33 | 14 | 8 | 3 | 3 | 3 | 1 | 0 | 2 | 7.4 | 1.9 | 9.4 | 9.3 | 1.6 | 4.8 | 1.04 |
| Craig Kimbrel | | cl | 36 | 6 | 2 | 2 | 3 | 2 | 0 | 0 | 4 | 9.4 | 4.4 | 14.4 | 9.4 | 2.0 | 2.1 | 1.54 |
| John King* | StL | mr | 29 | 3 | 0 | 5 | 3 | 0 | 0 | 1 | 0 | 8.3 | 2.2 | 10.9 | 4.9 | 0.7 | 2.3 | 1.16 |
| Michael King | Tam | mr | 29 | 21 | 6 | 1 | 10 | 6 | 1 | 0 | 1 | 7.8 | 3.3 | 11.6 | 11.3 | 1.6 | 3.5 | 1.23 |
| George Kirby | Sea | sp | 26 | 24 | 6 | 0 | 5 | 5 | 1 | 0 | 5 | 10.0 | 1.1 | 11.3 | 7.8 | 1.2 | 7.3 | 1.23 |
| Andrew Kittredge | ChN | mr | 34 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 9.2 | 1.5 | 10.7 | 4.6 | 1.5 | 3.0 | 1.19 |
| Will Klein | Mia | mr | 24 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 6.8 | 4.5 | 12.8 | 6.8 | 0.8 | 1.5 | 1.25 |
| Jared Koenig* | Tam | mr | 30 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 7.8 | 2.1 | 11.4 | 7.1 | 2.8 | 3.3 | 1.11 |
| Michael Kopech | SF | sp | 28 | 24 | 4 | 0 | 6 | 5 | 0 | 0 | 6 | 10.4 | 5.7 | 16.7 | 8.5 | 1.8 | 1.5 | 1.79 |
| Dean Kremer | Det | sp | 28 | 23 | 9 | 0 | 6 | 7 | 0 | 0 | 3 | 7.5 | 2.0 | 9.7 | 8.0 | 1.1 | 4.0 | 1.06 |
| Alex Lange | LAN | cl | 28 | 3 | 1 | 0 | 0 | 18 | 0 | 1 | 2 | 7.1 | 3.2 | 10.3 | 11.5 | 0.4 | 3.5 | 1.15 |
| Jake Latz* | Phi | mr | 28 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 10.4 | 1.0 | 11.4 | 12.5 | 3.1 | 12.0 | 1.27 |
| Nate Lavender* | ChA | mr | 24 | 7 | 3 | 1 | 5 | 2 | 1 | 0 | 2 | 7.6 | 3.7 | 11.9 | 11.5 | 0.8 | 3.1 | 1.26 |
| Justin Lawrence | Bos | mr | 29 | 4 | 0 | 0 | 7 | 1 | 0 | 0 | 2 | 6.2 | 4.8 | 12.0 | 9.0 | 0.4 | 1.9 | 1.22 |
| Max Lazar | NYA | mr | 25 | 11 | 3 | 1 | 1 | 6 | 0 | 0 | 5 | 10.1 | 2.0 | 12.2 | 6.3 | 1.4 | 3.1 | 1.35 |
| Jose Leclerc | Pit | mr | 30 | 6 | 4 | 2 | 2 | 2 | 0 | 0 | 6 | 7.9 | 5.0 | 13.1 | 9.5 | 1.4 | 1.9 | 1.42 |
| Dylan Lee* | | mr | 29 | 3 | 0 | 1 | 1 | 2 | 1 | 0 | 2 | 7.7 | 1.9 | 9.7 | 9.7 | 0.8 | 5.1 | 1.06 |
| Jack Leiter | SF | sp | 24 | 29 | 3 | 0 | 3 | 4 | 0 | 1 | 6 | 9.8 | 4.8 | 14.9 | 9.5 | 1.7 | 2.0 | 1.63 |
| Mark Leiter | Bos | mr | 33 | 10 | 1 | 0 | 8 | 3 | 0 | 0 | 0 | 5.5 | 2.8 | 9.1 | 9.4 | 0.8 | 3.4 | 0.92 |
| Matthew Liberatore* | | sp | 24 | 8 | 4 | 0 | 4 | 4 | 0 | 1 | 2 | 8.7 | 2.7 | 11.7 | 8.2 | 0.9 | 3.1 | 1.27 |
| Yu-Min Lin* | Bal | sp | 20 | 25 | 7 | 0 | 13 | 11 | 2 | 0 | 4 | 7.7 | 3.3 | 11.6 | 9.3 | 0.8 | 2.8 | 1.22 |
| Zack Littell | Cle | mr | 28 | 5 | 3 | 0 | 8 | 4 | 0 | 0 | 3 | 8.8 | 1.8 | 11.1 | 7.9 | 1.0 | 4.4 | 1.18 |
| Brendon Little* | LAN | mr | 27 | 16 | 1 | 4 | 3 | 12 | 0 | 0 | 4 | 9.2 | 3.9 | 13.4 | 6.9 | 1.1 | 1.8 | 1.45 |
| Luke Little* | Hou | mr | 23 | 5 | 1 | 0 | 1 | 3 | 0 | 0 | 0 | 8.9 | 5.4 | 14.6 | 13.3 | 1.0 | 2.5 | 1.59 |
| Ben Lively | | sp | 32 | 16 | 8 | 0 | 6 | 0 | 2 | 0 | 4 | 8.6 | 2.4 | 11.4 | 7.9 | 1.1 | 3.2 | 1.23 |
| Mauricio Llovera | StL | mr | 28 | 6 | 1 | 0 | 4 | 2 | 0 | 0 | 1 | 9.9 | 1.4 | 12.2 | 7.8 | 1.4 | 5.7 | 1.26 |
| Jonathan Loaisiga | Ari | mr | 29 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 8.4 | 0.8 | 9.3 | 10.1 | 1.7 | 12.0 | 1.03 |
| Nick Lodolo* | | sp | 26 | 7 | 2 | 3 | 2 | 4 | 0 | 0 | 1 | 7.8 | 2.1 | 10.2 | 10.3 | 1.1 | 4.9 | 1.10 |
| Pablo Lopez | Tex | sp | 28 | 26 | 8 | 0 | 15 | 9 | 0 | 0 | 8 | 7.6 | 2.3 | 10.4 | 9.7 | 0.9 | 4.3 | 1.09 |
| Reynaldo Lopez | LAA | mr | 30 | 9 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 7.1 | 3.1 | 10.2 | 11.8 | 1.0 | 3.8 | 1.13 |
| Michael Lorenzen | LAA | sp | 32 | 8 | 3 | 2 | 5 | 4 | 0 | 0 | 3 | 7.2 | 2.8 | 10.6 | 6.3 | 0.9 | 2.2 | 1.12 |
| Ryan Loutos | Mia | mr | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.0 | 9.0 | 36.0 | 9.0 | 9.0 | 1.0 | 4.00 |
| Richard Lovelady* | | mr | 28 | 0 | 2 | 0 | 3 | 1 | 0 | 0 | 1 | 7.4 | 3.1 | 11.5 | 6.8 | 0.9 | 2.2 | 1.17 |
| Seth Lugo | NYN | sp | 34 | 10 | 6 | 0 | 6 | 2 | 1 | 0 | 4 | 7.4 | 1.9 | 9.6 | 7.2 | 1.1 | 3.7 | 1.04 |
| Jesus Luzardo* | Cle | sp | 26 | 16 | 3 | 0 | 3 | 4 | 0 | 1 | 2 | 8.3 | 2.7 | 11.3 | 10.6 | 0.8 | 3.9 | 1.22 |
| Daniel Lynch* | Phi | sp | 27 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 5.1 | 11.8 | 8.4 | 0.0 | 1.7 | 1.31 |
| Lance Lynn | LAN | sp | 37 | 31 | 5 | 2 | 11 | 4 | 0 | 1 | 7 | 8.0 | 2.1 | 10.5 | 8.1 | 1.1 | 3.9 | 1.12 |
| Adam Macko* | | sp | 23 | 12 | 3 | 0 | 3 | 7 | 0 | 0 | 0 | 9.8 | 4.8 | 15.1 | 9.1 | 1.6 | 1.9 | 1.63 |
| Kenta Maeda | Mil | sp | 36 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 6.2 | 2.1 | 8.3 | 6.9 | 0.0 | 3.3 | 0.92 |
| Tyler Mahle | Ari | sp | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 3.2 | 7.1 | 8.4 | 0.0 | 2.6 | 0.79 |
| Anthony Maldonado | Tor | mr | 26 | 5 | 2 | 2 | 5 | 5 | 1 | 0 | 2 | 9.0 | 3.4 | 12.9 | 10.4 | 1.0 | 3.0 | 1.38 |
| Matt Manning | Mia | sp | 26 | 9 | 3 | 0 | 1 | 1 | 0 | 1 | 2 | 6.7 | 2.3 | 9.1 | 6.8 | 0.8 | 2.9 | 1.00 |
| Alek Manoah | Sea | sp | 26 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | 1 | 9.6 | 2.9 | 12.5 | 10.8 | 0.8 | 3.7 | 1.38 |
| Joe Mantiply* | KC | mr | 33 | 3 | 3 | 1 | 2 | 1 | 0 | 0 | 1 | 7.3 | 1.9 | 9.5 | 8.5 | 0.6 | 4.6 | 1.02 |
| Ron Marinaccio | ChA | mr | 28 | 13 | 4 | 0 | 5 | 4 | 0 | 0 | 4 | 9.5 | 5.1 | 15.2 | 9.4 | 1.5 | 1.8 | 1.62 |
| German Marquez | Bos | sp | 29 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 3.7 | 2.1 | 5.8 | 7.9 | 0.0 | 3.8 | 0.65 |
| Alec Marsh | | sp | 26 | 12 | 6 | 0 | 4 | 10 | 1 | 0 | 2 | 9.8 | 3.2 | 13.4 | 9.0 | 0.9 | 2.8 | 1.44 |
| Chris Martin | ChN | mr | 38 | 2 | 1 | 1 | 1 | 0 | 1 | 0 | 2 | 7.1 | 0.8 | 8.2 | 7.4 | 0.5 | 9.0 | 0.88 |
| Davis Martin | SD | sp | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 5.4 | 14.4 | 9.0 | 3.6 | 1.7 | 1.60 |
| Justin Martinez | Tex | mr | 22 | 7 | 2 | 0 | 4 | 3 | 1 | 1 | 2 | 7.1 | 7.1 | 14.8 | 11.6 | 1.3 | 1.6 | 1.57 |
| Nick Martinez | Mil | mr | 33 | 25 | 10 | 0 | 9 | 4 | 2 | 1 | 6 | 8.3 | 2.5 | 11.2 | 8.9 | 0.9 | 3.6 | 1.20 |
| Seth Martinez | Hou | mr | 29 | 23 | 8 | 2 | 10 | 2 | 0 | 1 | 3 | 9.7 | 2.9 | 13.4 | 8.4 | 1.2 | 2.9 | 1.40 |
| Phil Maton | | mr | 31 | 3 | 3 | 0 | 10 | 2 | 1 | 0 | 1 | 7.8 | 3.5 | 12.6 | 10.8 | 1.4 | 3.1 | 1.25 |
| Yuki Matsui* | NYN | mr | 28 | 3 | 2 | 0 | 2 | 1 | 0 | 0 | 0 | 5.6 | 5.0 | 10.9 | 12.5 | 0.3 | 2.5 | 1.18 |
| Steven Matz* | | sp | 33 | 2 | 0 | 0 | 5 | 3 | 0 | 0 | 3 | 7.3 | 3.2 | 11.5 | 8.3 | 0.4 | 2.6 | 1.16 |
| Tyler Matzek* | SD | mr | 33 | 1 | 0 | 1 | 2 | 1 | 0 | 0 | 1 | 6.1 | 3.9 | 11.0 | 12.1 | 1.7 | 3.1 | 1.10 |
| Tim Mayza* | | mr | 32 | 5 | 0 | 2 | 2 | 1 | 0 | 0 | 0 | 10.1 | 1.8 | 12.8 | 7.3 | 0.5 | 4.0 | 1.32 |
| James McArthur | Det | mr | 27 | 1 | 0 | 0 | 2 | 0 | 1 | 0 | 0 | 14.0 | 0.0 | 16.2 | 6.5 | 1.1 | 99.0 | 1.56 |
| Chayce McDermott | LAN | sp | 25 | 23 | 8 | 0 | 8 | 7 | 0 | 0 | 9 | 6.8 | 3.7 | 10.9 | 8.9 | 0.8 | 2.4 | 1.17 |
| Griff McGarry | Bal | sp | 25 | 4 | 2 | 0 | 3 | 10 | 1 | 0 | 1 | 8.7 | 6.6 | 15.8 | 9.2 | 0.6 | 1.4 | 1.71 |
| Scott McGough | Hou | mr | 34 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 11.4 | 3.6 | 14.9 | 11.0 | 2.1 | 3.1 | 1.66 |
| Michael McGreevy | ChA | sp | 23 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 8.6 | 2.5 | 11.2 | 5.8 | 0.7 | 2.3 | 1.24 |
| Evan McKendry | SD | sp | 26 | 7 | 1 | 0 | 7 | 2 | 0 | 0 | 2 | 8.6 | 1.7 | 11.1 | 5.5 | 0.7 | 3.3 | 1.14 |
| Triston McKenzie | | sp | 26 | 19 | 9 | 0 | 4 | 10 | 0 | 0 | 11 | 9.7 | 2.0 | 11.9 | 7.4 | 1.5 | 3.6 | 1.30 |
| John McMillon | Pit | mr | 26 | 4 | 0 | 2 | 0 | 5 | 0 | 1 | 2 | 9.9 | 9.2 | 19.1 | 11.2 | 0.7 | 1.2 | 2.12 |
| John Means* | Tex | sp | 31 | 3 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 6.9 | 0.7 | 9.0 | 8.3 | 0.7 | 12.0 | 0.85 |
| Nick Mears | | mr | 27 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 6.8 | 9.0 | 15.8 | 3.4 | 1.1 | 0.4 | 1.75 |
| Trevor Megill | | mr | 30 | 7 | 0 | 0 | 4 | 3 | 0 | 1 | 1 | 6.8 | 3.5 | 11.3 | 13.1 | 1.4 | 3.7 | 1.15 |
| Tylor Megill | NYN | sp | 28 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6.4 | 0.0 | 6.4 | 6.4 | 0.0 | 99.0 | 0.71 |
| Juan M. Mejia | Mia | mr | 23 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 6.3 | 2.7 | 9.0 | 6.3 | 1.8 | 2.3 | 1.00 |
| Cristian Mena | Col | sp | 21 | 26 | 11 | 0 | 4 | 15 | 0 | 0 | 3 | 9.9 | 3.2 | 13.3 | 7.7 | 1.7 | 2.4 | 1.45 |
| Michael Mercado | NYA | mr | 25 | 6 | 4 | 0 | 0 | 5 | 0 | 0 | 2 | 9.5 | 3.4 | 12.9 | 9.2 | 1.1 | 2.7 | 1.43 |
| Julian Merryweather | | mr | 32 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 7.3 | 0.9 | 8.2 | 14.2 | 0.9 | 15.5 | 0.92 |
| Max Meyer | ChA | sp | 25 | 16 | 15 | 0 | 3 | 4 | 0 | 0 | 4 | 8.5 | 3.1 | 11.8 | 8.5 | 1.3 | 2.8 | 1.29 |
| Miles Mikolas | StL | sp | 35 | 14 | 5 | 0 | 6 | 7 | 0 | 1 | 5 | 8.0 | 1.1 | 9.4 | 6.4 | 0.8 | 5.5 | 1.02 |
| Bobby Miller | Bal | sp | 25 | 24 | 12 | 0 | 7 | 11 | 0 | 0 | 6 | 7.7 | 2.5 | 10.6 | 8.5 | 0.5 | 3.4 | 1.14 |
| Bryce Miller | | sp | 25 | 19 | 11 | 0 | 11 | 2 | 0 | 1 | 4 | 8.2 | 1.9 | 10.5 | 7.6 | 0.9 | 4.1 | 1.12 |
| Erik Miller* | | mr | 26 | 4 | 1 | 0 | 2 | 1 | 0 | 0 | 2 | 9.4 | 6.5 | 16.6 | 15.3 | 2.0 | 2.3 | 1.77 |
| Mason Miller | Bos | mr | 25 | 4 | 2 | 0 | 5 | 2 | 1 | 0 | 2 | 4.4 | 3.5 | 8.5 | 11.1 | 0.6 | 3.2 | 0.88 |
| Tyson Miller | | mr | 28 | 5 | 2 | 2 | 3 | 2 | 0 | 0 | 0 | 11.6 | 2.7 | 15.1 | 9.2 | 1.2 | 3.4 | 1.58 |
| Hoby Milner* | Cin | mr | 33 | 1 | 4 | 1 | 4 | 0 | 0 | 0 | 1 | 7.0 | 2.3 | 10.1 | 9.5 | 0.8 | 4.2 | 1.03 |
| A.J. Minter* | Was | mr | 30 | 7 | 1 | 1 | 2 | 2 | 0 | 0 | 2 | 9.0 | 3.2 | 13.0 | 10.4 | 1.8 | 3.2 | 1.36 |
| Andrew Misiaszek* | Cin | mr | 26 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.5 | 8.5 | 17.1 | 5.7 | 0.0 | 0.7 | 1.89 |
| Jacob Misiorowski | Tex | sp | 22 | 12 | 1 | 0 | 14 | 7 | 0 | 0 | 1 | 8.8 | 6.1 | 17.1 | 10.7 | 1.1 | 1.8 | 1.66 |
| Casey Mize | | sp | 27 | 15 | 4 | 5 | 9 | 0 | 0 | 0 | 2 | 7.8 | 2.2 | 10.6 | 7.4 | 0.8 | 3.3 | 1.11 |
| Sam Moll* | Tor | mr | 32 | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 7.6 | 1.8 | 9.4 | 9.4 | 1.2 | 5.3 | 1.04 |
| Frankie Montas | ChN | sp | 31 | 13 | 2 | 0 | 6 | 4 | 0 | 0 | 0 | 9.5 | 2.6 | 13.0 | 9.9 | 0.9 | 3.8 | 1.35 |
| Keider Montero | | sp | 23 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 8.6 | 1.1 | 10.3 | 6.9 | 1.1 | 6.0 | 1.09 |
| Jordan Montgomery* | | sp | 31 | 21 | 8 | 4 | 9 | 6 | 1 | 0 | 8 | 8.3 | 2.1 | 10.7 | 8.2 | 0.8 | 3.9 | 1.15 |
| Matt Moore* | Min | mr | 35 | 7 | 2 | 0 | 1 | 3 | 0 | 0 | 2 | 8.8 | 2.6 | 11.6 | 9.7 | 1.6 | 3.8 | 1.27 |
| Francisco Morales | LAN | mr | 24 | 11 | 5 | 0 | 2 | 6 | 1 | 0 | 1 | 6.2 | 4.3 | 10.9 | 9.2 | 0.3 | 2.1 | 1.17 |
| Adrian Morejon* | | mr | 25 | 6 | 0 | 4 | 2 | 2 | 0 | 0 | 0 | 9.9 | 3.1 | 13.4 | 8.3 | 1.3 | 2.7 | 1.44 |
| Eli Morgan | Det | mr | 28 | 15 | 5 | 0 | 5 | 1 | 0 | 1 | 4 | 6.5 | 1.8 | 8.6 | 10.0 | 0.5 | 5.6 | 0.92 |
| Charlie Morton | SD | sp | 40 | 10 | 13 | 0 | 15 | 4 | 0 | 0 | 7 | 7.2 | 3.5 | 11.4 | 9.4 | 0.9 | 2.7 | 1.19 |
| Kyle Muller* | Tor | sp | 26 | 2 | 2 | 0 | 0 | 2 | 1 | 0 | 0 | 11.9 | 2.6 | 14.5 | 9.2 | 1.0 | 3.5 | 1.61 |
| Andres Munoz | Sea | mr | 25 | 12 | 2 | 0 | 5 | 8 | 1 | 1 | 2 | 7.7 | 2.7 | 11.0 | 14.5 | 1.1 | 5.5 | 1.16 |
| Roddery Munoz | Tex | sp | 24 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 10.8 | 2.7 | 13.5 | 0.0 | 0.0 | 0.0 | 1.50 |
| Ryan Murphy | SF | sp | 24 | 11 | 5 | 0 | 4 | 3 | 0 | 0 | 5 | 9.4 | 3.0 | 12.9 | 6.7 | 1.1 | 2.2 | 1.38 |
| Joe Musgrove | | sp | 31 | 11 | 1 | 0 | 21 | 0 | 3 | 0 | 3 | 7.2 | 1.9 | 10.6 | 7.7 | 0.7 | 4.1 | 1.01 |
| Tobias Myers | | sp | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.9 | 2.5 | 7.4 | 7.4 | 0.6 | 3.0 | 0.82 |
| Andrew Nardi* | Atl | mr | 25 | 6 | 2 | 2 | 1 | 3 | 0 | 1 | 3 | 7.3 | 3.9 | 11.4 | 10.4 | 2.0 | 2.7 | 1.25 |
| Nick Nastrini | SD | sp | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.4 | 0.0 | 14.4 | 12.6 | 1.8 | 99.0 | 1.60 |
| Packy Naughton* | Was | sp | 28 | 8 | 3 | 3 | 1 | 1 | 0 | 0 | 4 | 8.3 | 1.9 | 10.4 | 6.5 | 1.1 | 3.4 | 1.14 |
| Jack Neely | | mr | 24 | 10 | 4 | 3 | 5 | 21 | 0 | 1 | 7 | 8.5 | 4.6 | 13.6 | 10.5 | 1.4 | 2.3 | 1.46 |
| Kyle Nelson* | Atl | mr | 27 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 9.9 | 1.4 | 12.8 | 9.9 | 0.0 | 7.0 | 1.26 |
| Ryne Nelson | Cin | sp | 26 | 13 | 8 | 0 | 7 | 4 | 1 | 1 | 3 | 9.1 | 1.9 | 11.4 | 6.8 | 1.1 | 3.6 | 1.22 |
| Hector Neris | Cin | mr | 35 | 7 | 1 | 0 | 3 | 3 | 0 | 0 | 1 | 5.5 | 2.9 | 8.8 | 11.0 | 1.0 | 3.7 | 0.94 |
| Kyle Nicolas | Atl | sp | 25 | 6 | 2 | 0 | 6 | 5 | 0 | 0 | 2 | 10.7 | 4.2 | 16.0 | 9.2 | 2.4 | 2.2 | 1.66 |
| Aaron Nola | Cle | sp | 31 | 16 | 9 | 0 | 8 | 2 | 1 | 0 | 6 | 7.7 | 1.2 | 9.2 | 9.7 | 0.8 | 8.2 | 0.99 |
| Dedniel Nunez | Tex | mr | 28 | 21 | 1 | 2 | 1 | 6 | 0 | 0 | 5 | 7.5 | 4.8 | 12.5 | 7.9 | 1.1 | 1.6 | 1.37 |
| Bailey Ober | | sp | 28 | 6 | 5 | 0 | 3 | 0 | 0 | 0 | 4 | 8.3 | 1.6 | 10.0 | 8.2 | 1.3 | 5.3 | 1.10 |
| Pierson Ohl | KC | sp | 24 | 20 | 9 | 0 | 5 | 4 | 0 | 0 | 2 | 10.2 | 0.8 | 11.2 | 6.8 | 1.1 | 8.3 | 1.22 |
| Shohei Ohtani | Tex | dh | 29 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 8.1 | 1.3 | 10.3 | 9.0 | 1.3 | 6.7 | 1.05 |
| Steven Okert* | KC | mr | 32 | 5 | 4 | 0 | 5 | 2 | 0 | 0 | 2 | 9.8 | 2.7 | 13.2 | 10.6 | 2.1 | 3.9 | 1.38 |
| Mat Olsen | NYN | mr | 23 | 13 | 3 | 1 | 9 | 0 | 0 | 0 | 2 | 7.7 | 2.6 | 11.2 | 8.6 | 1.4 | 3.3 | 1.15 |
| Reese Olson | | sp | 24 | 16 | 5 | 0 | 2 | 4 | 1 | 0 | 6 | 10.4 | 3.8 | 14.3 | 7.9 | 1.3 | 2.1 | 1.57 |
| Kaleb Ort | Hou | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 11.6 | 25.1 | 11.6 | 0.0 | 1.0 | 2.79 |
| Luis L. Ortiz | | sp | 25 | 10 | 4 | 0 | 4 | 5 | 0 | 0 | 5 | 10.9 | 4.4 | 15.8 | 7.9 | 1.4 | 1.8 | 1.70 |
| Michel Otanez | Tex | mr | 26 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 49.5 | 27.0 | 81.0 | 18.0 | 18.0 | 0.7 | 8.50 |
| Adam Ottavino | SD | mr | 38 | 3 | 2 | 0 | 3 | 5 | 0 | 0 | 3 | 10.8 | 4.2 | 15.6 | 10.6 | 0.4 | 2.5 | 1.67 |
| Chris Paddack | | sp | 28 | 13 | 4 | 0 | 6 | 1 | 0 | 0 | 3 | 7.1 | 1.6 | 9.0 | 9.2 | 1.0 | 5.9 | 0.96 |
| Emilio Pagan | ChA | mr | 33 | 7 | 3 | 1 | 2 | 2 | 0 | 0 | 2 | 4.8 | 3.5 | 8.7 | 7.6 | 0.4 | 2.2 | 0.92 |
| Daniel Palencia | Mia | mr | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.4 | 0.0 | 5.4 | 5.4 | 0.0 | 99.0 | 0.60 |
| Andre Pallante | Min | mr | 25 | 5 | 3 | 0 | 2 | 7 | 0 | 0 | 5 | 9.8 | 2.5 | 12.6 | 6.0 | 1.2 | 2.4 | 1.37 |
| Carson Palmquist* | Ari | sp | 23 | 5 | 1 | 1 | 9 | 0 | 2 | 0 | 0 | 6.4 | 3.2 | 11.3 | 9.7 | 0.8 | 3.1 | 1.06 |
| Enoli Paredes | NYA | mr | 28 | 1 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 10.2 | 4.6 | 14.8 | 9.1 | 2.4 | 2.0 | 1.64 |
| Mitchell Parker* | Atl | sp | 24 | 12 | 7 | 3 | 2 | 7 | 0 | 1 | 6 | 9.8 | 4.0 | 13.9 | 8.6 | 1.2 | 2.2 | 1.53 |
| Joel Payamps | Cin | mr | 30 | 3 | 2 | 0 | 3 | 0 | 0 | 0 | 1 | 9.2 | 3.7 | 13.5 | 7.4 | 1.0 | 2.0 | 1.43 |
| Nate Pearson | | mr | 27 | 7 | 4 | 0 | 5 | 10 | 1 | 0 | 0 | 7.6 | 4.7 | 12.9 | 11.1 | 1.2 | 2.4 | 1.38 |
| Elvis Peguero | | mr | 27 | 5 | 0 | 1 | 4 | 3 | 0 | 0 | 1 | 7.6 | 2.1 | 10.3 | 9.5 | 1.0 | 4.6 | 1.08 |
| Walter Pennington* | | mr | 26 | 1 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 9.2 | 5.3 | 15.1 | 11.2 | 0.0 | 2.1 | 1.61 |
| Ryan Pepiot | | sp | 26 | 20 | 4 | 0 | 7 | 1 | 0 | 0 | 5 | 6.3 | 3.5 | 10.2 | 8.5 | 1.1 | 2.4 | 1.09 |
| Freddy Peralta | | sp | 28 | 23 | 7 | 0 | 11 | 3 | 0 | 1 | 4 | 7.8 | 3.3 | 11.6 | 10.0 | 1.1 | 3.1 | 1.23 |
| Wandy Peralta* | SD | mr | 32 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 5.3 | 5.3 | 10.7 | 9.7 | 0.3 | 1.8 | 1.19 |
| Cionel Perez* | Mil | mr | 28 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2.3 | 4.5 | 6.8 | 11.3 | 0.0 | 2.5 | 0.75 |
| Martin Perez* | LAN | sp | 33 | 26 | 9 | 3 | 14 | 3 | 2 | 0 | 5 | 9.5 | 1.6 | 11.8 | 6.7 | 1.2 | 4.2 | 1.24 |
| Jack Perkins | Bal | sp | 26 | 1 | 2 | 1 | 1 | 0 | 0 | 0 | 1 | 6.1 | 4.7 | 11.2 | 7.0 | 0.5 | 1.5 | 1.19 |
| David Peterson* | Oak | sp | 28 | 14 | 1 | 0 | 7 | 8 | 1 | 0 | 1 | 8.1 | 2.9 | 11.5 | 9.4 | 1.0 | 3.2 | 1.23 |
| Brandon Pfaadt | Col | sp | 25 | 23 | 9 | 0 | 7 | 5 | 1 | 0 | 10 | 8.8 | 2.3 | 11.4 | 8.7 | 1.1 | 3.8 | 1.24 |
| Evan Phillips | Mil | cl | 29 | 2 | 0 | 2 | 4 | 0 | 3 | 0 | 2 | 7.8 | 1.4 | 9.8 | 9.8 | 1.2 | 7.3 | 1.02 |
| Nick Pivetta | Was | sp | 31 | 15 | 8 | 0 | 4 | 8 | 2 | 1 | 3 | 7.2 | 3.0 | 10.5 | 8.6 | 2.2 | 2.9 | 1.13 |
| Colin Poche* | Col | mr | 30 | 3 | 0 | 2 | 2 | 2 | 1 | 0 | 2 | 8.9 | 4.8 | 14.2 | 10.7 | 1.5 | 2.2 | 1.52 |
| Cade Povich* | Bos | sp | 24 | 19 | 9 | 1 | 10 | 7 | 0 | 0 | 3 | 8.8 | 2.9 | 12.3 | 8.4 | 1.5 | 2.9 | 1.30 |
| Ryan Pressly | Cin | cl | 35 | 1 | 3 | 2 | 2 | 4 | 1 | 1 | 2 | 7.0 | 2.2 | 9.5 | 9.9 | 0.5 | 4.5 | 1.03 |
| A.J. Puk* | LAN | mr | 29 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.9 | 1.9 | 2.8 | 14.0 | 0.0 | 7.5 | 0.31 |
| Jose Quijada* | Mia | mr | 28 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.4 | 4.3 | 9.7 | 8.6 | 3.2 | 2.0 | 1.08 |
| Jose Quintana* | Pit | sp | 35 | 20 | 5 | 2 | 4 | 3 | 1 | 1 | 1 | 8.7 | 2.4 | 11.3 | 8.0 | 0.7 | 3.3 | 1.23 |
| Cole Ragans* | Was | sp | 26 | 7 | 7 | 0 | 5 | 3 | 0 | 0 | 2 | 7.9 | 1.6 | 10.0 | 9.4 | 1.3 | 5.8 | 1.06 |
| Taylor Rashi | ChN | mr | 28 | 6 | 4 | 0 | 3 | 3 | 0 | 0 | 2 | 7.1 | 2.8 | 10.2 | 8.0 | 0.6 | 2.9 | 1.10 |
| Drew Rasmussen | Bos | sp | 28 | 5 | 3 | 0 | 1 | 0 | 0 | 1 | 2 | 5.9 | 3.4 | 9.4 | 7.9 | 0.2 | 2.3 | 1.03 |
| Robbie Ray* | StL | sp | 32 | 5 | 0 | 0 | 3 | 1 | 0 | 0 | 1 | 12.4 | 2.5 | 15.8 | 7.0 | 1.7 | 2.8 | 1.66 |
| Marco Raya | Mia | sp | 21 | 6 | 3 | 0 | 5 | 2 | 0 | 0 | 2 | 8.9 | 2.6 | 12.1 | 7.1 | 2.2 | 2.7 | 1.28 |
| Colin Rea | Mil | sp | 33 | 7 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 8.9 | 0.8 | 9.9 | 7.6 | 1.5 | 10.0 | 1.08 |
| Sean Reid-Foley | | mr | 28 | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 10.6 | 6.5 | 18.0 | 12.3 | 0.0 | 1.9 | 1.91 |
| Sean Reynolds | Mia | mr | 26 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 6.4 | 4.8 | 12.7 | 4.8 | 1.6 | 1.0 | 1.24 |
| Trevor Richards | NYN | mr | 31 | 9 | 7 | 0 | 9 | 9 | 1 | 0 | 6 | 7.7 | 3.2 | 11.4 | 11.0 | 1.5 | 3.4 | 1.22 |
| Sem Robberse | Pit | sp | 22 | 25 | 6 | 0 | 6 | 6 | 1 | 0 | 3 | 8.7 | 2.3 | 11.3 | 7.0 | 0.7 | 3.0 | 1.22 |
| Ethan Roberts | Oak | mr | 26 | 1 | 1 | 0 | 7 | 5 | 0 | 0 | 2 | 7.8 | 1.9 | 10.8 | 8.4 | 0.5 | 4.5 | 1.08 |
| David Robertson | | cl | 39 | 1 | 1 | 0 | 3 | 2 | 0 | 0 | 2 | 9.8 | 2.8 | 13.5 | 8.6 | 1.8 | 3.1 | 1.40 |
| Nick Robertson | Cin | mr | 25 | 2 | 0 | 0 | 1 | 2 | 0 | 1 | 0 | 8.8 | 2.1 | 11.1 | 8.2 | 1.0 | 3.9 | 1.21 |
| Joe Rock* | Cle | sp | 23 | 10 | 5 | 0 | 7 | 4 | 0 | 0 | 1 | 7.0 | 2.3 | 9.8 | 8.3 | 0.8 | 3.7 | 1.03 |
| Carlos Rodon* | ChA | sp | 31 | 35 | 7 | 2 | 9 | 8 | 1 | 2 | 4 | 7.5 | 3.1 | 11.0 | 10.3 | 1.0 | 3.3 | 1.18 |
| Carlos F. Rodriguez | Tor | sp | 22 | 9 | 2 | 0 | 4 | 2 | 0 | 0 | 2 | 7.8 | 3.2 | 11.8 | 9.1 | 1.1 | 2.9 | 1.22 |
| Eduardo Rodriguez* | Min | sp | 31 | 5 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 10.9 | 2.8 | 14.1 | 7.8 | 1.1 | 2.8 | 1.52 |
| Grayson Rodriguez | Tex | sp | 24 | 11 | 6 | 0 | 7 | 4 | 0 | 1 | 2 | 7.1 | 2.4 | 9.8 | 9.7 | 1.2 | 4.1 | 1.05 |
| Manuel Rodriguez | Pit | mr | 27 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 7.4 | 4.7 | 12.1 | 7.4 | 0.9 | 1.6 | 1.34 |
| Randy Rodriguez | Hou | mr | 24 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.4 | 5.4 | 13.5 | 13.5 | 0.0 | 2.5 | 1.20 |
| Yariel Rodriguez | ChN | mr | 27 | 6 | 0 | 1 | 7 | 2 | 0 | 0 | 1 | 8.8 | 3.5 | 13.8 | 9.7 | 1.1 | 2.8 | 1.37 |
| Yerry Rodriguez | LAN | mr | 26 | 12 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 12.0 | 4.2 | 16.4 | 8.5 | 1.2 | 2.0 | 1.80 |
| Taylor Rogers* | Ari | mr | 33 | 6 | 4 | 2 | 2 | 0 | 1 | 0 | 3 | 5.0 | 1.8 | 7.1 | 11.2 | 0.3 | 6.3 | 0.75 |
| Trevor Rogers* | SF | sp | 26 | 17 | 3 | 0 | 4 | 0 | 0 | 0 | 4 | 9.7 | 2.3 | 12.3 | 9.5 | 1.2 | 4.2 | 1.33 |
| Tyler Rogers | StL | mr | 33 | 7 | 1 | 1 | 3 | 0 | 0 | 0 | 3 | 7.3 | 1.2 | 8.8 | 6.4 | 0.8 | 5.4 | 0.94 |
| Jordan Romano | Cle | cl | 31 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.7 | 1.9 | 7.6 | 12.2 | 1.5 | 6.4 | 0.85 |
| JoJo Romero* | | mr | 27 | 8 | 3 | 2 | 2 | 3 | 0 | 0 | 5 | 7.3 | 2.1 | 9.7 | 10.2 | 1.1 | 4.8 | 1.05 |
| Landen Roupp | | sp | 25 | 17 | 6 | 3 | 4 | 0 | 0 | 1 | 1 | 9.1 | 3.9 | 13.4 | 6.5 | 1.9 | 1.6 | 1.45 |
| Jackson Rutledge | SF | sp | 25 | 13 | 4 | 0 | 7 | 7 | 0 | 0 | 4 | 10.5 | 2.7 | 14.0 | 6.3 | 0.7 | 2.3 | 1.46 |
| Joe Ryan | Mia | sp | 28 | 12 | 8 | 0 | 11 | 1 | 0 | 2 | 5 | 7.1 | 1.9 | 9.5 | 9.1 | 1.2 | 4.8 | 1.00 |
| Andrew Saalfrank* | Mia | mr | 26 | 2 | 1 | 0 | 2 | 3 | 1 | 0 | 0 | 6.6 | 3.8 | 10.8 | 9.4 | 0.7 | 2.5 | 1.15 |
| Chris Sale* | LAA | sp | 35 | 21 | 4 | 5 | 9 | 1 | 0 | 0 | 1 | 7.0 | 2.0 | 9.5 | 11.8 | 0.8 | 6.0 | 1.00 |
| Cristopher Sanchez* | Tam | sp | 27 | 30 | 8 | 1 | 9 | 3 | 0 | 0 | 4 | 8.7 | 1.4 | 10.5 | 7.7 | 0.8 | 5.5 | 1.12 |
| Nick Sandlin | Atl | mr | 27 | 13 | 1 | 0 | 5 | 0 | 1 | 0 | 4 | 7.9 | 3.5 | 12.0 | 8.7 | 1.1 | 2.5 | 1.27 |
| Patrick Sandoval* | | sp | 27 | 12 | 1 | 3 | 4 | 3 | 0 | 0 | 2 | 10.7 | 4.1 | 15.6 | 9.6 | 0.2 | 2.4 | 1.64 |
| Cole Sands | | mr | 26 | 12 | 2 | 2 | 2 | 3 | 0 | 0 | 2 | 8.1 | 2.4 | 10.7 | 8.6 | 0.6 | 3.5 | 1.17 |
| Tony Santillan | Col | mr | 27 | 8 | 3 | 0 | 5 | 2 | 0 | 0 | 3 | 9.8 | 7.0 | 17.8 | 7.6 | 0.7 | 1.1 | 1.87 |
| Gregory Santos | LAA | mr | 24 | 4 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 6.6 | 2.5 | 9.7 | 9.7 | 0.5 | 3.8 | 1.02 |
| Tayler Saucedo* | Mil | mr | 31 | 1 | 0 | 1 | 3 | 2 | 1 | 0 | 0 | 8.0 | 1.7 | 10.7 | 9.0 | 1.7 | 5.2 | 1.08 |
| Josh Sborz | SD | mr | 30 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.0 | 4.1 | 9.2 | 12.4 | 0.5 | 3.0 | 1.02 |
| Max Scherzer | | sp | 39 | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 8.8 | 1.6 | 10.5 | 7.7 | 1.4 | 4.7 | 1.16 |
| Clarke Schmidt | Col | sp | 28 | 19 | 8 | 0 | 9 | 8 | 0 | 1 | 2 | 8.6 | 4.3 | 13.6 | 8.4 | 0.9 | 2.0 | 1.43 |
| John Schreiber | ChA | mr | 30 | 8 | 0 | 0 | 3 | 1 | 1 | 0 | 3 | 8.0 | 3.2 | 11.7 | 7.9 | 1.3 | 2.5 | 1.25 |
| Christian Scott | | sp | 25 | 26 | 6 | 0 | 14 | 0 | 0 | 0 | 4 | 8.7 | 1.9 | 11.7 | 7.1 | 0.7 | 3.6 | 1.18 |
| Tanner Scott* | NYN | mr | 29 | 2 | 4 | 1 | 3 | 5 | 0 | 0 | 3 | 6.8 | 3.3 | 10.5 | 11.8 | 1.1 | 3.6 | 1.12 |
| Tayler Scott | Phi | mr | 32 | 7 | 1 | 0 | 4 | 7 | 1 | 0 | 1 | 9.2 | 4.8 | 14.9 | 9.2 | 0.9 | 1.9 | 1.55 |
| JP Sears* | Cin | sp | 28 | 6 | 1 | 1 | 9 | 0 | 1 | 1 | 1 | 8.5 | 2.4 | 11.9 | 6.3 | 1.5 | 2.6 | 1.22 |
| Luis Severino | Tex | sp | 30 | 29 | 9 | 0 | 9 | 2 | 1 | 0 | 5 | 10.0 | 3.3 | 13.8 | 8.4 | 1.5 | 2.6 | 1.48 |
| Paul Sewald | LAA | cl | 34 | 1 | 4 | 2 | 4 | 0 | 0 | 0 | 4 | 7.8 | 3.0 | 11.5 | 9.1 | 1.5 | 3.1 | 1.19 |
| Ian Seymour* | Mia | sp | 25 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 8.4 | 0.9 | 9.7 | 10.2 | 0.9 | 11.5 | 1.03 |
| Davis Sharpe | Atl | mr | 24 | 19 | 6 | 0 | 9 | 18 | 1 | 0 | 6 | 8.7 | 1.6 | 10.9 | 8.9 | 1.1 | 5.6 | 1.14 |
| Chase Silseth | Sea | sp | 24 | 2 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 6.3 | 3.2 | 9.8 | 10.2 | 1.1 | 3.2 | 1.05 |
| Lucas Sims | Col | mr | 30 | 0 | 0 | 0 | 5 | 2 | 0 | 0 | 0 | 9.7 | 6.0 | 16.7 | 12.5 | 2.0 | 2.1 | 1.75 |
| Brady Singer | LAN | sp | 27 | 27 | 10 | 0 | 13 | 6 | 0 | 0 | 5 | 8.5 | 2.1 | 11.1 | 8.7 | 1.0 | 4.2 | 1.17 |
| Tarik Skubal* | Tam | sp | 27 | 27 | 11 | 0 | 8 | 3 | 0 | 0 | 10 | 9.5 | 1.8 | 11.6 | 8.6 | 1.1 | 4.9 | 1.25 |
| Cade Smith | Tam | mr | 25 | 5 | 1 | 0 | 10 | 7 | 0 | 0 | 6 | 7.0 | 4.1 | 12.5 | 9.7 | 0.8 | 2.4 | 1.23 |
| Drew Smith | NYN | mr | 30 | 4 | 1 | 1 | 2 | 0 | 1 | 0 | 0 | 6.8 | 3.0 | 10.5 | 10.5 | 0.0 | 3.6 | 1.08 |
| Will Smith* | ChN | cl | 34 | 9 | 0 | 3 | 0 | 3 | 1 | 0 | 4 | 7.7 | 4.2 | 11.9 | 9.3 | 1.9 | 2.2 | 1.32 |
| AJ Smith-Shawver | Tex | sp | 21 | 10 | 3 | 0 | 1 | 6 | 0 | 0 | 2 | 8.1 | 5.4 | 13.6 | 9.0 | 1.3 | 1.7 | 1.49 |
| Blake Snell* | Cin | sp | 31 | 21 | 4 | 5 | 1 | 7 | 0 | 0 | 3 | 7.3 | 4.6 | 12.0 | 11.4 | 1.2 | 2.5 | 1.33 |
| Robby Snelling* | Bal | sp | 20 | 26 | 9 | 0 | 3 | 0 | 2 | 0 | 6 | 7.9 | 3.6 | 11.7 | 6.5 | 1.0 | 1.8 | 1.29 |
| Collin Snider | Bos | mr | 28 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.1 | 3.1 | 16.2 | 8.5 | 2.3 | 2.8 | 1.80 |
| Jose Soriano | | mr | 25 | 11 | 4 | 1 | 14 | 8 | 1 | 0 | 1 | 7.6 | 3.8 | 12.4 | 10.6 | 1.9 | 2.8 | 1.26 |
| Mike Soroka | Ari | sp | 26 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 9.8 | 0.0 | 10.4 | 7.4 | 0.0 | 99.0 | 1.09 |
| Gregory Soto* | Cle | mr | 29 | 1 | 1 | 2 | 3 | 7 | 0 | 1 | 2 | 6.6 | 3.0 | 10.2 | 12.3 | 1.1 | 4.1 | 1.07 |
| Gabe Speier* | Was | mr | 29 | 4 | 2 | 1 | 3 | 2 | 1 | 0 | 1 | 9.0 | 1.6 | 11.5 | 8.1 | 0.3 | 5.2 | 1.17 |
| Mitch Spence | SF | sp | 26 | 18 | 5 | 0 | 5 | 2 | 1 | 0 | 2 | 8.2 | 2.4 | 11.0 | 7.5 | 0.6 | 3.1 | 1.18 |
| Carson Spiers | Cle | sp | 26 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 6.4 | 0.0 | 7.7 | 7.7 | 0.0 | 99.0 | 0.71 |
| Jeffrey Springs* | Bos | sp | 31 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 1 | 5.6 | 1.5 | 7.3 | 9.6 | 1.2 | 6.2 | 0.79 |
| Garrett Stallings | LAA | sp | 26 | 11 | 1 | 0 | 3 | 4 | 0 | 0 | 0 | 10.4 | 2.8 | 13.6 | 7.4 | 1.9 | 2.7 | 1.46 |
| Ryne Stanek | | mr | 32 | 2 | 6 | 0 | 1 | 1 | 0 | 0 | 1 | 7.0 | 2.5 | 9.7 | 9.7 | 0.2 | 3.8 | 1.05 |
| Cody Stashak | Cle | mr | 30 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 10.3 | 2.0 | 12.3 | 11.2 | 1.8 | 5.7 | 1.37 |
| Josh Staumont | Phi | mr | 30 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.8 | 4.8 | 10.6 | 10.6 | 0.0 | 2.2 | 1.07 |
| Justin Steele* | Tex | sp | 28 | 15 | 5 | 3 | 8 | 9 | 1 | 1 | 3 | 7.2 | 2.3 | 9.9 | 8.4 | 0.8 | 3.7 | 1.05 |
| Brock Stewart | Tex | mr | 32 | 3 | 0 | 0 | 1 | 2 | 0 | 0 | 1 | 5.9 | 4.1 | 10.5 | 12.4 | 1.8 | 3.0 | 1.12 |
| Gavin Stone | | sp | 25 | 15 | 6 | 2 | 0 | 5 | 1 | 3 | 4 | 9.0 | 2.1 | 11.1 | 7.7 | 1.2 | 3.7 | 1.23 |
| Matt Strahm* | Tor | mr | 32 | 10 | 8 | 0 | 3 | 0 | 0 | 0 | 2 | 8.1 | 2.8 | 11.2 | 9.4 | 1.2 | 3.3 | 1.22 |
| Hunter Stratton | | mr | 27 | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 8.6 | 3.8 | 12.7 | 10.3 | 1.1 | 2.7 | 1.38 |
| Spencer Strider | Sea | sp | 25 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.4 | 3.6 | 8.0 | 16.1 | 0.7 | 4.4 | 0.89 |
| Marcus Stroman | Tam | sp | 33 | 29 | 5 | 0 | 3 | 4 | 3 | 0 | 7 | 8.9 | 2.5 | 11.6 | 7.0 | 0.6 | 2.7 | 1.27 |
| Peter Strzelecki | KC | mr | 29 | 19 | 4 | 2 | 5 | 0 | 0 | 0 | 2 | 7.8 | 3.0 | 11.3 | 9.5 | 1.0 | 3.1 | 1.20 |
| Jose Suarez* | | sp | 26 | 6 | 1 | 0 | 2 | 1 | 1 | 0 | 1 | 8.0 | 2.2 | 10.5 | 10.0 | 1.2 | 4.6 | 1.13 |
| Ranger Suarez* | ChN | sp | 28 | 7 | 8 | 5 | 4 | 1 | 0 | 1 | 4 | 8.3 | 3.0 | 11.5 | 7.7 | 1.0 | 2.5 | 1.26 |
| Robert Suarez | Tam | mr | 33 | 4 | 2 | 4 | 2 | 1 | 0 | 0 | 2 | 5.8 | 6.4 | 12.5 | 9.2 | 1.9 | 1.4 | 1.35 |
| Brent Suter* | LAN | mr | 34 | 3 | 1 | 0 | 0 | 1 | 0 | 0 | 3 | 7.2 | 2.7 | 9.9 | 8.6 | 1.0 | 3.2 | 1.10 |
| Erik Swanson | SD | mr | 30 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 10.1 | 2.0 | 12.2 | 10.6 | 0.6 | 5.4 | 1.34 |
| Devin Sweet | Oak | mr | 27 | 3 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 8.5 | 2.3 | 11.2 | 9.8 | 1.2 | 4.3 | 1.20 |
| Jameson Taillon | Tam | sp | 32 | 18 | 10 | 0 | 4 | 3 | 0 | 0 | 3 | 7.9 | 1.9 | 10.0 | 8.1 | 0.8 | 4.2 | 1.09 |
| Dillon Tate | StL | mr | 30 | 1 | 1 | 0 | 3 | 1 | 0 | 0 | 0 | 6.6 | 4.0 | 12.0 | 5.8 | 0.9 | 1.4 | 1.18 |
| Dylan Tebrake | SD | mr | 24 | 3 | 0 | 0 | 0 | 4 | 1 | 0 | 2 | 5.5 | 3.3 | 8.8 | 9.4 | 0.9 | 2.8 | 0.98 |
| Caleb Thielbar* | Pit | mr | 37 | 4 | 1 | 4 | 1 | 0 | 0 | 0 | 3 | 6.8 | 2.4 | 9.3 | 9.9 | 1.3 | 4.1 | 1.02 |
| Ryan Thompson | Bos | mr | 32 | 2 | 0 | 1 | 4 | 1 | 0 | 0 | 0 | 8.5 | 2.2 | 11.3 | 7.1 | 1.8 | 3.2 | 1.19 |
| Zack Thompson* | SF | sp | 26 | 7 | 1 | 1 | 6 | 7 | 0 | 0 | 2 | 7.9 | 4.2 | 12.6 | 6.9 | 0.7 | 1.7 | 1.34 |
| Trent Thornton | Mil | mr | 30 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 3 | 10.0 | 3.2 | 13.8 | 7.6 | 1.8 | 2.4 | 1.47 |
| Ricky Tiedemann* | Tex | sp | 21 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 7.7 | 6.4 | 14.1 | 9.0 | 0.0 | 1.4 | 1.57 |
| Michael Tonkin | NYN | mr | 34 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 6.0 | 3.0 | 9.0 | 6.0 | 0.0 | 2.0 | 1.00 |
| Blake Treinen | Pit | mr | 36 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 11.6 | 3.9 | 15.4 | 8.5 | 0.8 | 2.2 | 1.71 |
| Edwin Uceta | Pit | mr | 26 | 2 | 2 | 0 | 2 | 1 | 0 | 0 | 0 | 10.0 | 3.0 | 13.9 | 4.8 | 0.9 | 1.6 | 1.45 |
| Abner Uribe | Sea | mr | 24 | 1 | 2 | 0 | 0 | 1 | 0 | 0 | 2 | 7.2 | 5.0 | 12.1 | 13.8 | 0.6 | 2.8 | 1.35 |
| Framber Valdez* | LAA | sp | 30 | 14 | 9 | 1 | 16 | 4 | 0 | 1 | 2 | 7.2 | 2.4 | 10.4 | 8.6 | 0.6 | 3.5 | 1.07 |
| Reid VanScoter* | KC | sp | 25 | 26 | 6 | 0 | 9 | 7 | 2 | 0 | 8 | 10.3 | 1.3 | 12.0 | 6.6 | 1.1 | 5.1 | 1.29 |
| Louie Varland | Atl | sp | 26 | 18 | 7 | 0 | 6 | 4 | 0 | 1 | 4 | 10.0 | 2.7 | 13.1 | 8.1 | 1.2 | 3.0 | 1.42 |
| Mike Vasil | Ari | sp | 24 | 17 | 7 | 0 | 2 | 9 | 1 | 1 | 2 | 8.4 | 2.8 | 11.4 | 8.4 | 1.4 | 2.9 | 1.25 |
| Randy Vasquez | Det | sp | 25 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7.8 | 3.6 | 12.1 | 9.9 | 2.8 | 2.8 | 1.26 |
| Justin Verlander | SD | sp | 41 | 7 | 10 | 0 | 3 | 3 | 0 | 1 | 3 | 7.6 | 2.6 | 10.4 | 6.8 | 0.7 | 2.6 | 1.13 |
| Alex Vesia* | Atl | mr | 28 | 1 | 1 | 6 | 1 | 1 | 0 | 0 | 3 | 5.3 | 5.0 | 10.4 | 10.8 | 0.7 | 2.2 | 1.14 |
| Nick Vespi* | Det | mr | 28 | 4 | 0 | 1 | 0 | 2 | 0 | 0 | 3 | 7.9 | 1.9 | 9.7 | 6.0 | 1.4 | 3.2 | 1.08 |
| Will Vest | | mr | 29 | 3 | 0 | 0 | 3 | 5 | 0 | 0 | 1 | 11.5 | 3.3 | 15.5 | 9.3 | 1.6 | 2.8 | 1.64 |
| Thyago Vieira | Mia | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 3.9 | 7.7 | 11.6 | 0.0 | 3.0 | 0.86 |
| Darius Vines | Tor | sp | 26 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 5.3 | 3.0 | 9.0 | 6.0 | 0.0 | 2.0 | 0.92 |
| Victor Vodnik | NYA | mr | 24 | 2 | 2 | 0 | 1 | 5 | 0 | 0 | 4 | 7.5 | 4.3 | 12.0 | 7.5 | 1.1 | 1.7 | 1.31 |
| Austin Voth | NYN | mr | 32 | 12 | 13 | 0 | 7 | 5 | 0 | 1 | 2 | 7.7 | 2.7 | 10.8 | 7.6 | 1.0 | 2.8 | 1.16 |
| Michael Wacha | | sp | 32 | 16 | 5 | 0 | 3 | 4 | 0 | 0 | 2 | 8.5 | 2.3 | 11.0 | 7.7 | 1.3 | 3.4 | 1.19 |
| Hurston Waldrep | Atl | sp | 22 | 8 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 9.0 | 3.6 | 12.6 | 10.0 | 0.9 | 2.8 | 1.40 |
| Matt Waldron | | sp | 27 | 26 | 9 | 0 | 9 | 2 | 1 | 0 | 2 | 8.6 | 2.2 | 11.3 | 7.2 | 1.4 | 3.2 | 1.20 |
| Ryan Walker | | mr | 28 | 2 | 2 | 2 | 1 | 2 | 0 | 0 | 0 | 10.0 | 2.5 | 12.7 | 11.9 | 1.4 | 4.7 | 1.40 |
| Taijuan Walker | | sp | 31 | 6 | 4 | 0 | 3 | 0 | 0 | 0 | 1 | 8.9 | 2.3 | 11.8 | 8.2 | 1.3 | 3.5 | 1.25 |
| Blake Walston* | ChN | sp | 23 | 25 | 3 | 0 | 7 | 0 | 0 | 1 | 4 | 6.2 | 3.7 | 10.5 | 7.9 | 0.5 | 2.1 | 1.10 |
| Will Warren | ChN | sp | 25 | 3 | 1 | 10 | 2 | 4 | 0 | 0 | 2 | 8.4 | 4.7 | 13.4 | 6.1 | 1.3 | 1.3 | 1.46 |
| Ryan Weathers* | Col | sp | 24 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 11.0 | 3.9 | 15.3 | 6.3 | 0.4 | 1.6 | 1.65 |
| Luke Weaver | Tam | sp | 30 | 8 | 1 | 1 | 1 | 2 | 0 | 0 | 2 | 10.7 | 4.0 | 14.9 | 7.6 | 1.4 | 1.9 | 1.63 |
| Jacob Webb | Mil | mr | 30 | 7 | 4 | 1 | 1 | 2 | 0 | 0 | 2 | 9.6 | 1.9 | 11.6 | 11.1 | 1.7 | 5.9 | 1.27 |
| Logan Webb | Oak | sp | 27 | 26 | 5 | 2 | 8 | 4 | 0 | 0 | 1 | 7.8 | 1.0 | 9.1 | 6.8 | 0.8 | 6.9 | 0.97 |
| Tyler Wells | StL | sp | 29 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 6.0 | 4.5 | 11.3 | 6.8 | 0.8 | 1.5 | 1.17 |
| Joey Wentz* | | sp | 26 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 6.9 | 2.5 | 9.8 | 8.3 | 1.0 | 3.4 | 1.04 |
| Hayden Wesneski | Col | sp | 26 | 5 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 8.0 | 2.6 | 10.7 | 8.1 | 1.5 | 3.1 | 1.18 |
| Zack Wheeler | | sp | 34 | 18 | 11 | 0 | 12 | 3 | 1 | 1 | 6 | 7.8 | 2.0 | 10.3 | 8.8 | 0.6 | 4.3 | 1.09 |
| Carson Whisenhunt* | KC | sp | 23 | 1 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 6.0 | 6.8 | 12.8 | 11.3 | 0.0 | 1.7 | 1.42 |
| Brendan White | Was | mr | 25 | 6 | 2 | 0 | 2 | 0 | 0 | 1 | 1 | 9.6 | 3.5 | 13.6 | 7.3 | 0.6 | 2.1 | 1.45 |
| Garrett Whitlock | Oak | mr | 28 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 8.3 | 4.2 | 12.5 | 9.1 | 0.8 | 2.2 | 1.38 |
| Jordan Wicks* | Tam | sp | 24 | 3 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 6.8 | 1.1 | 8.2 | 7.5 | 0.7 | 7.0 | 0.87 |
| Brad Wieck* | Cle | mr | 32 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 10.5 | 7.0 | 17.5 | 15.0 | 1.0 | 2.1 | 1.94 |
| Devin Williams | | cl | 29 | 3 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 8.1 | 6.0 | 14.6 | 12.0 | 0.9 | 2.0 | 1.57 |
| Gavin Williams | Ari | sp | 24 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 8.0 | 2.9 | 11.3 | 8.0 | 0.0 | 2.8 | 1.22 |
| Brandon Williamson* | Col | sp | 26 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 11.2 | 5.9 | 17.8 | 7.2 | 0.7 | 1.2 | 1.90 |
| Bryse Wilson | Tor | mr | 26 | 3 | 4 | 0 | 2 | 4 | 0 | 0 | 3 | 9.9 | 1.5 | 11.6 | 5.9 | 1.2 | 3.9 | 1.27 |
| Steven Wilson | Det | mr | 29 | 4 | 1 | 0 | 2 | 0 | 0 | 0 | 1 | 9.8 | 5.6 | 16.1 | 7.5 | 1.1 | 1.3 | 1.71 |
| Allan Winans | SD | sp | 28 | 10 | 6 | 0 | 7 | 8 | 0 | 0 | 8 | 7.6 | 1.9 | 10.0 | 7.7 | 0.6 | 4.0 | 1.06 |
| Josh Winckowski | KC | mr | 26 | 11 | 3 | 1 | 4 | 0 | 0 | 0 | 2 | 8.1 | 2.9 | 11.3 | 7.7 | 1.0 | 2.6 | 1.23 |
| Josh Winder | Mia | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.7 | 8.1 | 10.8 | 8.1 | 0.0 | 1.0 | 1.20 |
| Keaton Winn | SF | sp | 26 | 18 | 4 | 0 | 4 | 3 | 1 | 0 | 3 | 10.3 | 2.0 | 12.8 | 9.2 | 0.8 | 4.6 | 1.37 |
| Bryan Woo | Bos | sp | 24 | 15 | 2 | 0 | 5 | 2 | 0 | 0 | 1 | 7.3 | 2.2 | 9.8 | 9.0 | 0.9 | 4.2 | 1.05 |
| Alex Wood* | ChN | sp | 33 | 4 | 4 | 0 | 11 | 3 | 0 | 0 | 1 | 7.1 | 1.2 | 10.0 | 8.6 | 0.2 | 7.1 | 0.93 |
| Simeon Woods Richardso | | sp | 23 | 5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 8.5 | 3.9 | 12.3 | 8.9 | 0.8 | 2.3 | 1.37 |
| Yoshinobu Yamamoto | Col | sp | 25 | 2 | 3 | 0 | 2 | 4 | 0 | 0 | 3 | 8.2 | 2.0 | 10.3 | 8.0 | 1.0 | 4.0 | 1.13 |
| Kirby Yates | StL | mr | 37 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 0 | 6.2 | 8.5 | 16.2 | 12.3 | 0.0 | 1.5 | 1.63 |
| Huascar Ynoa | Mil | sp | 26 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 1 | 4.0 | 1.3 | 8.1 | 9.4 | 0.0 | 7.0 | 0.60 |
| Brandon Young | Hou | sp | 25 | 4 | 2 | 0 | 1 | 1 | 0 | 0 | 0 | 9.9 | 2.2 | 12.4 | 6.9 | 0.7 | 3.2 | 1.34 |
| Ryan Zeferjahn | Bos | mr | 26 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 9.0 | 1.5 | 13.5 | 1.5 | 3.0 | 1.0 | 1.17 |
| Angel Zerpa* | Bal | sp | 24 | 7 | 3 | 1 | 3 | 3 | 0 | 1 | 5 | 9.8 | 3.6 | 13.9 | 5.4 | 1.0 | 1.5 | 1.49 |
| Yosver Zulueta | Col | mr | 26 | 11 | 4 | 0 | 8 | 3 | 0 | 1 | 3 | 13.2 | 7.0 | 21.8 | 8.4 | 2.2 | 1.2 | 2.24 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| Andrew Abbott* | | sp | 25 | .772 | 412 | .335 | 324 | .488 | 326 | .491 | 87.0 | 5.0 | 4.52 | 4.34 |
| Mick Abel | Sea | sp | 22 | .758 | 90 | .356 | 67 | .456 | 69 | .469 | 19.5 | 5.3 | 4.69 | 4.97 |
| Bryan Abreu | Sea | mr | 27 | .544 | 160 | .275 | 112 | .346 | 116 | .358 | 21.6 | 2.4 | 2.12 | 2.12 |
| Jason Adam | Ari | mr | 32 | .577 | 196 | .199 | 123 | .363 | 133 | .392 | 26.2 | 2.7 | 2.46 | 2.29 |
| Austin L. Adams | Hou | mr | 33 | .717 | 21 | .333 | 20 | .400 | 24 | .480 | 5.4 | 4.5 | 4.07 | 6.05 |
| Ty Adcock | Det | mr | 27 | .639 | 173 | .283 | 102 | .389 | 106 | .405 | 24.2 | 3.3 | 2.97 | 2.65 |
| Keegan Akin* | LAA | mr | 29 | .747 | 136 | .331 | 98 | .452 | 101 | .465 | 28.9 | 5.4 | 4.88 | 4.74 |
| Jorge Alcala | Bal | mr | 28 | .623 | 275 | .258 | 171 | .388 | 179 | .406 | 37.1 | 3.0 | 2.76 | 2.61 |
| Franco Aleman | Col | mr | 24 | .728 | 144 | .340 | 96 | .427 | 101 | .449 | 28.2 | 5.0 | 4.63 | 4.48 |
| Scott Alexander* | | mr | 34 | .961 | 58 | .362 | 46 | .590 | 47 | .603 | 16.5 | 8.9 | 8.16 | 7.51 |
| Tyler Alexander* | ChA | mr | 29 | .775 | 598 | .306 | 414 | .484 | 421 | .492 | 111.3 | 4.8 | 4.39 | 4.23 |
| Logan T. Allen* | Was | sp | 25 | .687 | 481 | .293 | 285 | .422 | 288 | .426 | 69.0 | 3.7 | 3.41 | 3.43 |
| Jose Alvarado* | Ari | mr | 29 | .583 | 125 | .320 | 92 | .368 | 94 | .376 | 20.3 | 3.0 | 2.74 | 2.43 |
| Adbert Alzolay | ChN | cl | 29 | .720 | 158 | .310 | 108 | .452 | 110 | .460 | 25.5 | 3.8 | 3.40 | 3.09 |
| Ian Anderson | Atl | sp | 26 | .783 | 227 | .344 | 160 | .471 | 162 | .476 | 47.0 | 5.7 | 5.03 | 5.47 |
| Nick Anderson | Was | mr | 33 | .702 | 151 | .265 | 108 | .456 | 108 | .456 | 26.1 | 4.0 | 3.60 | 3.17 |
| Tyler Anderson* | | sp | 34 | .743 | 518 | .295 | 347 | .459 | 355 | .470 | 91.8 | 4.5 | 4.05 | 3.92 |
| Luarbert Arias | Col | mr | 23 | .891 | 332 | .380 | 273 | .549 | 278 | .559 | 87.3 | 7.2 | 6.61 | 6.04 |
| Shawn Armstrong | Ari | mr | 33 | .609 | 453 | .265 | 264 | .375 | 272 | .386 | 58.9 | 3.0 | 2.68 | 2.45 |
| Spencer Arrighetti | | sp | 24 | .774 | 461 | .297 | 344 | .484 | 351 | .494 | 94.4 | 5.1 | 4.60 | 4.65 |
| Aaron Ashby* | SD | sp | 26 | .572 | 92 | .239 | 54 | .372 | 54 | .372 | 11.0 | 2.7 | 2.39 | 1.99 |
| Braxton Ashcraft | Atl | sp | 24 | .765 | 338 | .331 | 208 | .455 | 213 | .466 | 62.1 | 5.3 | 4.82 | 4.62 |
| Graham Ashcraft | Was | sp | 26 | .663 | 470 | .260 | 261 | .405 | 269 | .418 | 65.0 | 3.7 | 3.37 | 3.14 |
| Pedro Avila | | sp | 27 | .637 | 63 | .270 | 36 | .379 | 39 | .411 | 8.8 | 3.3 | 3.06 | 2.61 |
| Anthony Banda* | Mia | mr | 30 | .754 | 15 | .267 | 10 | .476 | 10 | .476 | 2.4 | 4.4 | 3.94 | 4.93 |
| Tanner Banks* | Tam | mr | 32 | .627 | 194 | .237 | 121 | .405 | 123 | .411 | 26.4 | 3.1 | 2.82 | 2.47 |
| Scott Barlow | ChN | mr | 31 | .724 | 158 | .310 | 124 | .461 | 126 | .468 | 33.0 | 4.7 | 4.29 | 4.01 |
| Jaime Barria | ChN | mr | 27 | .690 | 137 | .248 | 84 | .449 | 84 | .449 | 18.9 | 3.5 | 3.19 | 2.80 |
| Chris Bassitt | Mil | sp | 35 | .599 | 649 | .248 | 342 | .363 | 358 | .380 | 76.3 | 2.8 | 2.57 | 2.33 |
| Brady Basso* | Min | sp | 26 | .935 | 95 | .379 | 79 | .577 | 81 | .591 | 26.9 | 8.1 | 7.33 | 6.75 |
| Mike Baumann | Bal | mr | 28 | .635 | 60 | .217 | 42 | .424 | 42 | .424 | 8.4 | 3.1 | 2.83 | 3.25 |
| Jarod Bayless | Phi | mr | 27 | .995 | 32 | .313 | 33 | .635 | 34 | .654 | 10.5 | 8.6 | 7.76 | 7.95 |
| Shane Baz | Bal | sp | 25 | .705 | 438 | .281 | 306 | .434 | 319 | .452 | 83.2 | 4.5 | 4.09 | 3.95 |
| Eduard Bazardo | Pit | mr | 28 | .760 | 98 | .327 | 68 | .439 | 74 | .477 | 20.9 | 5.4 | 4.98 | 4.72 |
| David Bednar | Tam | cl | 29 | .656 | 145 | .276 | 105 | .422 | 106 | .426 | 24.0 | 3.6 | 3.27 | 3.21 |
| Jalen Beeks* | LAN | mr | 30 | .787 | 289 | .308 | 210 | .485 | 218 | .503 | 58.8 | 5.2 | 4.75 | 4.48 |
| Clayton Beeter | NYA | sp | 25 | .804 | 185 | .319 | 152 | .505 | 156 | .518 | 44.2 | 5.9 | 5.27 | 5.22 |
| Brayan Bello | Mil | sp | 25 | .756 | 566 | .304 | 377 | .469 | 381 | .474 | 101.9 | 4.8 | 4.39 | 4.22 |
| Anthony Bender | Mil | mr | 29 | .697 | 462 | .262 | 306 | .430 | 325 | .456 | 73.2 | 3.7 | 3.38 | 3.18 |
| Brennan Bernardino* | NYA | mr | 32 | .739 | 50 | .240 | 39 | .481 | 40 | .494 | 10.0 | 4.8 | 4.28 | 4.22 |
| Jose Berrios | Tor | sp | 30 | .771 | 576 | .311 | 417 | .483 | 425 | .492 | 111.9 | 4.8 | 4.36 | 4.07 |
| Prelander Berroa | SF | mr | 24 | .978 | 233 | .356 | 267 | .618 | 272 | .630 | 89.4 | 9.7 | 8.62 | 9.20 |
| Tanner Bibee | Was | sp | 25 | .761 | 414 | .302 | 304 | .478 | 308 | .484 | 86.9 | 5.3 | 4.89 | 4.47 |
| Phil Bickford | Mil | mr | 28 | .728 | 108 | .306 | 70 | .438 | 71 | .444 | 19.6 | 4.8 | 4.38 | 4.46 |
| Osvaldo Bido | Mia | sp | 28 | .707 | 25 | .240 | 18 | .450 | 19 | .475 | 4.0 | 3.7 | 3.36 | 3.56 |
| Shane Bieber | Tor | sp | 29 | .467 | 43 | .233 | 17 | .288 | 17 | .288 | 2.6 | 1.4 | 1.33 | 1.05 |
| Hunter Bigge | Sea | mr | 26 | .939 | 52 | .442 | 52 | .578 | 52 | .578 | 18.7 | 9.2 | 8.43 | 8.08 |
| Hayden Birdsong | Bos | sp | 22 | .729 | 192 | .276 | 139 | .444 | 148 | .473 | 39.5 | 4.9 | 4.46 | 4.24 |
| Mason Black | Min | sp | 24 | 1.083 | 13 | .385 | 17 | .708 | 17 | .708 | 5.7 | 10.3 | 9.29 | 10.23 |
| Ronel Blanco | Col | mr | 30 | .753 | 391 | .317 | 281 | .468 | 287 | .478 | 75.3 | 4.8 | 4.28 | 4.18 |
| Jonathan Bowlan | SF | sp | 27 | .849 | 282 | .312 | 211 | .533 | 213 | .538 | 63.3 | 6.3 | 5.78 | 5.65 |
| Joe Boyle | NYA | sp | 24 | .739 | 185 | .265 | 175 | .486 | 178 | .494 | 47.4 | 5.2 | 4.78 | 4.68 |
| Cody Bradford* | Tam | sp | 26 | .910 | 26 | .423 | 17 | .515 | 18 | .545 | 5.7 | 7.0 | 6.27 | 5.92 |
| Kyle Bradish | Bal | sp | 27 | .736 | 144 | .271 | 98 | .469 | 99 | .474 | 23.1 | 4.0 | 3.64 | 3.72 |
| Taj Bradley | | sp | 23 | .738 | 385 | .288 | 274 | .462 | 280 | .472 | 73.0 | 4.7 | 4.27 | 4.11 |
| Ryan Brasier | Pit | mr | 36 | .667 | 89 | .281 | 50 | .394 | 52 | .409 | 12.9 | 3.7 | 3.40 | 3.23 |
| Huascar Brazoban | NYN | mr | 34 | .991 | 36 | .306 | 33 | .647 | 33 | .647 | 10.1 | 7.8 | 7.04 | 7.12 |
| John Brebbia | ChA | mr | 34 | .000 | 3 | .000 | 0 | .000 | 0 | .000 | 0.0 | 0.0 | 0.00 | 0.00 |
| Beau Brieske | StL | mr | 26 | .824 | 40 | .150 | 30 | .566 | 31 | .585 | 7.9 | 5.5 | 4.91 | 4.23 |
| Trevor Brigden | Cin | mr | 28 | .651 | 85 | .271 | 60 | .420 | 60 | .420 | 12.9 | 3.3 | 2.95 | 3.45 |
| Jhony Brito | ChA | sp | 26 | .774 | 415 | .328 | 283 | .476 | 288 | .484 | 77.6 | 5.0 | 4.49 | 4.37 |
| Kyle Brnovich | StL | sp | 26 | .672 | 297 | .290 | 181 | .407 | 188 | .422 | 46.7 | 3.9 | 3.50 | 3.21 |
| T.J. Brock | Phi | mr | 24 | .554 | 56 | .286 | 23 | .307 | 24 | .320 | 6.2 | 3.2 | 2.84 | 2.61 |
| Ben Brown | Sea | sp | 24 | .817 | 216 | .352 | 179 | .510 | 182 | .519 | 49.3 | 5.5 | 4.91 | 5.17 |
| Hunter Brown | Hou | sp | 25 | .740 | 557 | .325 | 408 | .458 | 417 | .469 | 106.8 | 4.5 | 4.08 | 4.02 |
| Zach Brzykcy | Phi | mr | 24 | .882 | 173 | .341 | 171 | .552 | 176 | .568 | 51.2 | 6.8 | 6.12 | 6.66 |
| Kris Bubic* | Tex | sp | 26 | .618 | 115 | .209 | 71 | .386 | 76 | .413 | 16.0 | 3.2 | 2.94 | 2.94 |
| Walker Buehler | LAA | sp | 29 | .662 | 285 | .277 | 182 | .419 | 185 | .426 | 44.0 | 3.7 | 3.34 | 2.87 |
| Aaron Bummer* | Oak | mr | 30 | .772 | 98 | .388 | 84 | .472 | 85 | .478 | 25.4 | 6.0 | 5.37 | 5.40 |
| Brock Burke* | SD | mr | 27 | .681 | 129 | .279 | 77 | .410 | 81 | .431 | 19.5 | 3.7 | 3.44 | 3.13 |
| Sean Burke | LAA | sp | 24 | .959 | 17 | .176 | 19 | .655 | 19 | .655 | 5.2 | 7.9 | 7.08 | 8.37 |
| Corbin Burnes | Ari | sp | 29 | .614 | 657 | .289 | 405 | .380 | 412 | .386 | 95.5 | 3.3 | 2.94 | 2.72 |
| Mike Burrows | Tex | sp | 24 | .927 | 92 | .304 | 83 | .606 | 83 | .606 | 25.0 | 7.2 | 6.47 | 6.23 |
| Jose Butto | Sea | sp | 26 | .874 | 235 | .315 | 187 | .553 | 189 | .559 | 58.1 | 7.0 | 6.42 | 6.29 |
| Edward Cabrera | Atl | sp | 26 | .739 | 131 | .321 | 93 | .456 | 96 | .471 | 25.1 | 4.7 | 4.35 | 3.85 |
| Genesis Cabrera* | Tam | mr | 27 | .548 | 190 | .258 | 99 | .329 | 104 | .346 | 22.8 | 2.8 | 2.50 | 2.16 |
| Isaiah Campbell | Ari | mr | 26 | .920 | 59 | .322 | 61 | .610 | 62 | .620 | 15.9 | 5.9 | 5.22 | 5.57 |
| Griffin Canning | Cin | sp | 28 | .705 | 282 | .294 | 197 | .447 | 200 | .454 | 49.1 | 4.2 | 3.79 | 3.56 |
| Yennier Cano | ChN | mr | 30 | .606 | 210 | .257 | 115 | .369 | 119 | .381 | 25.9 | 3.0 | 2.69 | 2.55 |
| Joey Cantillo* | SF | sp | 24 | .737 | 402 | .311 | 297 | .455 | 303 | .464 | 84.3 | 5.2 | 4.70 | 4.68 |
| Luis Castillo | Bos | sp | 31 | .609 | 593 | .282 | 328 | .368 | 339 | .380 | 77.1 | 3.1 | 2.82 | 2.51 |
| Miguel Castro | Min | mr | 29 | .574 | 85 | .188 | 57 | .383 | 59 | .396 | 11.2 | 2.7 | 2.43 | 2.28 |
| Tim Cate* | LAN | mr | 26 | .710 | 78 | .244 | 48 | .440 | 49 | .450 | 12.7 | 4.5 | 4.06 | 3.72 |
| Dylan Cease | Mil | sp | 28 | .734 | 524 | .319 | 427 | .466 | 433 | .473 | 114.5 | 4.8 | 4.33 | 4.10 |
| Slade Cecconi | SD | sp | 25 | .623 | 612 | .248 | 324 | .376 | 340 | .394 | 75.9 | 3.1 | 2.87 | 2.64 |
| Andrew Chafin* | Oak | mr | 34 | .662 | 116 | .250 | 71 | .413 | 73 | .424 | 16.5 | 3.5 | 3.18 | 3.31 |
| Chandler Champlain | | sp | 24 | .796 | 280 | .304 | 195 | .499 | 197 | .504 | 57.7 | 5.9 | 5.38 | 4.96 |
| Aroldis Chapman* | LAA | mr | 36 | .559 | 105 | .219 | 90 | .380 | 91 | .384 | 19.8 | 3.1 | 2.83 | 2.73 |
| Jesse Chavez | ChA | mr | 40 | .859 | 262 | .279 | 231 | .566 | 233 | .571 | 64.4 | 6.2 | 5.67 | 5.61 |
| Aaron Civale | Min | sp | 29 | .739 | 464 | .297 | 311 | .461 | 317 | .470 | 82.1 | 4.6 | 4.13 | 3.81 |
| Emmanuel Clase | Sea | cl | 26 | .552 | 167 | .341 | 84 | .310 | 86 | .317 | 19.9 | 2.7 | 2.46 | 2.29 |
| Garrett Cleavinger* | Ari | mr | 30 | .678 | 153 | .314 | 129 | .429 | 133 | .442 | 31.2 | 3.9 | 3.46 | 3.52 |
| Alex Cobb | SD | sp | 36 | .768 | 97 | .351 | 61 | .469 | 61 | .469 | 15.9 | 4.5 | 4.03 | 3.95 |
| Isaac Coffey | Cin | sp | 24 | .606 | 442 | .244 | 232 | .360 | 247 | .384 | 58.8 | 3.4 | 3.06 | 2.75 |
| Gerrit Cole | Oak | sp | 33 | .717 | 286 | .290 | 208 | .458 | 211 | .465 | 54.5 | 4.5 | 4.08 | 3.56 |
| Luis Contreras | StL | mr | 28 | .708 | 117 | .265 | 82 | .439 | 86 | .460 | 21.2 | 4.3 | 4.10 | 4.10 |
| Roansy Contreras | Det | sp | 24 | .621 | 527 | .279 | 312 | .385 | 317 | .391 | 74.9 | 3.3 | 3.03 | 2.65 |
| Connor Cooke | Pit | mr | 24 | .780 | 298 | .329 | 238 | .483 | 245 | .497 | 69.7 | 5.6 | 5.16 | 5.01 |
| Nestor Cortes* | | sp | 29 | .611 | 619 | .255 | 340 | .380 | 345 | .385 | 74.4 | 2.9 | 2.69 | 2.42 |
| Tom Cosgrove* | | mr | 28 | .752 | 25 | .240 | 18 | .486 | 18 | .486 | 4.8 | 5.0 | 4.53 | 4.23 |
| Danny Coulombe* | Det | mr | 34 | .748 | 27 | .556 | 19 | .413 | 19 | .413 | 6.5 | 5.7 | 5.12 | 4.20 |
| Jake Cousins | Mil | mr | 29 | .582 | 11 | .091 | 9 | .391 | 10 | .435 | 1.9 | 3.2 | 2.91 | 3.28 |
| Austin Cox* | ChA | sp | 27 | .664 | 150 | .273 | 90 | .413 | 90 | .413 | 21.5 | 3.6 | 3.33 | 3.46 |
| Kutter Crawford | Det | sp | 28 | .747 | 320 | .297 | 218 | .466 | 222 | .474 | 57.9 | 4.6 | 4.20 | 4.10 |
| Garrett Crochet* | | mr | 25 | .711 | 149 | .302 | 112 | .446 | 115 | .458 | 29.2 | 4.5 | 4.05 | 3.76 |
| Declan Cronin | | mr | 26 | .892 | 199 | .357 | 148 | .529 | 154 | .550 | 48.5 | 7.1 | 6.41 | 6.57 |
| Hans Crouse | Sea | sp | 25 | 1.133 | 2 | .000 | 5 | .833 | 5 | .833 | 1.4 | 9.6 | 8.63 | 8.71 |
| Fernando Cruz | | mr | 34 | .546 | 35 | .286 | 23 | .315 | 26 | .356 | 4.6 | 2.2 | 2.01 | 2.18 |
| Hagen Danner | Cin | mr | 25 | .652 | 88 | .307 | 52 | .394 | 53 | .402 | 12.2 | 3.4 | 3.12 | 3.20 |
| Yu Darvish | | sp | 37 | .586 | 293 | .242 | 151 | .348 | 161 | .371 | 34.5 | 2.8 | 2.52 | 2.23 |
| Enyel De Los Santos | Mil | mr | 28 | .782 | 140 | .257 | 114 | .509 | 116 | .518 | 29.7 | 5.0 | 4.45 | 4.15 |
| Jacob deGrom | Cle | sp | 36 | .346 | 37 | .216 | 15 | .217 | 15 | .217 | 2.4 | 1.2 | 1.04 | 0.92 |
| Reid Detmers* | | sp | 24 | .699 | 521 | .278 | 353 | .439 | 362 | .450 | 86.2 | 3.9 | 3.54 | 3.40 |
| Chris Devenski | ChN | mr | 33 | .579 | 315 | .248 | 165 | .356 | 171 | .369 | 37.8 | 2.9 | 2.60 | 2.03 |
| Alexis Diaz | | cl | 27 | .548 | 131 | .252 | 76 | .310 | 89 | .363 | 18.7 | 2.8 | 2.57 | 2.34 |
| Edwin Diaz | | cl | 30 | .679 | 115 | .330 | 94 | .420 | 99 | .442 | 22.5 | 3.7 | 3.34 | 3.15 |
| Miguel Diaz | SD | mr | 29 | .826 | 116 | .362 | 88 | .500 | 90 | .511 | 26.5 | 6.1 | 5.59 | 5.78 |
| Yilber Diaz | | sp | 23 | .847 | 136 | .294 | 113 | .533 | 117 | .552 | 33.9 | 6.3 | 5.68 | 5.41 |
| Jake Diekman* | SD | mr | 37 | .837 | 8 | .250 | 9 | .563 | 9 | .563 | 2.3 | 5.6 | 6.16 | 7.85 |
| Hunter Dobbins | Sea | sp | 24 | .777 | 165 | .315 | 103 | .464 | 106 | .477 | 29.9 | 5.1 | 4.65 | 4.57 |
| Seranthony Dominguez | Was | mr | 29 | .690 | 180 | .306 | 132 | .434 | 133 | .438 | 30.8 | 3.8 | 3.44 | 3.88 |
| Camilo Doval | Oak | cl | 26 | .654 | 168 | .327 | 111 | .398 | 113 | .405 | 28.8 | 3.9 | 3.55 | 3.20 |
| Shawn Dubin | Was | sp | 28 | .713 | 183 | .284 | 129 | .446 | 133 | .460 | 34.3 | 4.5 | 4.04 | 3.69 |
| Dane Dunning | LAA | sp | 29 | .765 | 439 | .292 | 293 | .465 | 304 | .483 | 80.9 | 4.9 | 4.53 | 4.48 |
| Jhoan Duran | Sea | cl | 26 | .588 | 137 | .372 | 84 | .333 | 89 | .353 | 20.7 | 3.0 | 2.72 | 2.62 |
| Jake Eder* | Tex | sp | 25 | .963 | 161 | .311 | 168 | .615 | 173 | .634 | 57.7 | 9.1 | 8.06 | 7.26 |
| Scott Effross | Det | mr | 30 | .461 | 78 | .205 | 31 | .290 | 31 | .290 | 4.7 | 1.4 | 1.32 | 1.17 |
| Zach Eflin | | sp | 30 | .724 | 474 | .378 | 292 | .422 | 297 | .429 | 86.1 | 4.8 | 4.36 | 4.04 |
| Brandon Eisert* | Det | mr | 26 | .670 | 217 | .290 | 138 | .421 | 139 | .424 | 33.5 | 3.7 | 3.33 | 3.06 |
| Bryce Elder | | sp | 25 | .711 | 596 | .292 | 376 | .436 | 386 | .448 | 97.3 | 4.3 | 3.83 | 3.57 |
| Fraser Ellard* | Sea | mr | 26 | .875 | 4 | .500 | 7 | .583 | 7 | .583 | 2.0 | 9.1 | 8.18 | 9.51 |
| Nic Enright | | mr | 27 | .787 | 59 | .390 | 49 | .490 | 50 | .500 | 14.5 | 5.7 | 5.12 | 3.90 |
| Nathan Eovaldi | Oak | sp | 34 | .678 | 364 | .280 | 235 | .427 | 239 | .435 | 57.9 | 3.9 | 3.50 | 3.12 |
| Lucas Erceg | LAN | mr | 29 | .764 | 60 | .217 | 56 | .487 | 59 | .513 | 14.4 | 5.2 | 4.65 | 5.60 |
| Joey Estes | Mia | sp | 22 | .960 | 124 | .306 | 109 | .606 | 113 | .628 | 35.9 | 8.3 | 7.51 | 7.00 |
| Carlos Estevez | Tor | mr | 31 | .777 | 156 | .321 | 135 | .495 | 137 | .502 | 37.2 | 5.5 | 4.92 | 4.87 |
| Jeremiah Estrada | Sea | mr | 25 | .772 | 148 | .324 | 130 | .489 | 131 | .492 | 36.2 | 5.6 | 5.11 | 5.20 |
| Alex Faedo | Phi | sp | 28 | .793 | 437 | .316 | 318 | .494 | 323 | .502 | 92.6 | 5.6 | 5.07 | 4.59 |
| Pete Fairbanks | ChN | cl | 30 | .765 | 60 | .400 | 59 | .468 | 62 | .492 | 16.7 | 5.2 | 4.72 | 4.24 |
| Bailey Falter* | KC | sp | 27 | .728 | 147 | .320 | 92 | .436 | 95 | .450 | 26.8 | 4.9 | 4.43 | 3.93 |
| Calvin Faucher | Hou | mr | 28 | 1.092 | 55 | .345 | 60 | .690 | 61 | .701 | 21.1 | 10.9 | 9.85 | 9.66 |
| Erick Fedde | Hou | sp | 31 | 1.094 | 138 | .406 | 147 | .700 | 149 | .710 | 54.7 | 11.5 | 10.23 | 9.34 |
| Caleb Ferguson* | Tor | mr | 27 | .854 | 99 | .394 | 86 | .506 | 91 | .535 | 27.5 | 6.6 | 5.91 | 6.35 |
| Ryan Fernandez | SD | mr | 26 | .764 | 140 | .243 | 114 | .507 | 115 | .511 | 29.0 | 4.8 | 4.35 | 4.08 |
| Jose A. Ferrer* | Mia | mr | 24 | .837 | 28 | .357 | 22 | .500 | 23 | .523 | 7.2 | 6.9 | 6.04 | 5.37 |
| David Festa | | sp | 24 | .692 | 338 | .290 | 221 | .430 | 223 | .434 | 58.0 | 4.3 | 3.91 | 3.76 |
| J.P. Feyereisen | Pit | mr | 31 | .804 | 112 | .339 | 89 | .492 | 91 | .503 | 27.1 | 6.2 | 5.69 | 6.11 |
| Kyle Finnegan | NYN | cl | 32 | .695 | 155 | .213 | 117 | .468 | 118 | .472 | 25.4 | 3.6 | 3.27 | 3.20 |
| Richard Fitts | | sp | 24 | .641 | 398 | .271 | 205 | .381 | 210 | .390 | 51.0 | 3.4 | 3.13 | 2.90 |
| Jack Flaherty | Hou | sp | 28 | .636 | 559 | .252 | 337 | .394 | 349 | .408 | 79.2 | 3.4 | 3.09 | 3.03 |
| Josh Fleming* | Tam | mr | 28 | .771 | 28 | .357 | 15 | .455 | 15 | .455 | 3.0 | 3.1 | 2.83 | 3.50 |
| Wilmer Flores | ChN | sp | 23 | .328 | 12 | .167 | 3 | .158 | 4 | .211 | 0.6 | 1.2 | 1.04 | 0.95 |
| Dylan Floro | Was | mr | 33 | .675 | 103 | .350 | 58 | .395 | 59 | .401 | 15.0 | 3.8 | 3.50 | 3.29 |
| Mason Fluharty* | Phi | mr | 22 | .803 | 317 | .328 | 250 | .502 | 253 | .508 | 74.3 | 6.0 | 5.45 | 5.26 |
| Jason Foley | Oak | mr | 28 | .794 | 151 | .298 | 100 | .490 | 102 | .500 | 29.3 | 5.6 | 5.17 | 4.97 |
| J.P. France | KC | sp | 29 | .805 | 128 | .367 | 100 | .495 | 100 | .495 | 29.2 | 5.8 | 5.25 | 5.17 |
| Bowden Francis | Tex | sp | 28 | .630 | 99 | .222 | 61 | .399 | 64 | .418 | 12.6 | 2.9 | 2.64 | 2.64 |
| Kyle Freeland* | Min | sp | 31 | .702 | 16 | .313 | 8 | .381 | 9 | .429 | 2.3 | 4.1 | 3.72 | 3.46 |
| Luis Frias | Bal | mr | 26 | .796 | 330 | .348 | 254 | .490 | 255 | .492 | 77.1 | 6.2 | 5.57 | 5.75 |
| Max Fried* | Ari | sp | 30 | .565 | 583 | .281 | 286 | .331 | 295 | .342 | 63.0 | 2.6 | 2.32 | 2.12 |
| Kody Funderburk* | ChN | mr | 27 | .732 | 151 | .305 | 112 | .453 | 115 | .466 | 30.1 | 4.6 | 4.18 | 4.16 |
| Hunter Gaddis | Bos | sp | 26 | .700 | 460 | .276 | 297 | .421 | 316 | .448 | 80.7 | 4.4 | 3.96 | 3.81 |
| Giovanny Gallegos | | mr | 32 | .691 | 103 | .243 | 79 | .462 | 80 | .468 | 17.5 | 3.6 | 3.25 | 2.50 |
| Zac Gallen | | sp | 28 | .570 | 571 | .235 | 297 | .356 | 304 | .364 | 62.8 | 2.7 | 2.39 | 2.15 |
| Robert Garcia* | Was | mr | 28 | .685 | 96 | .271 | 65 | .436 | 65 | .436 | 15.4 | 3.9 | 3.53 | 3.74 |
| Yimi Garcia | | mr | 33 | .662 | 116 | .319 | 78 | .398 | 81 | .413 | 19.8 | 3.8 | 3.41 | 3.56 |
| Braxton Garrett* | Mia | sp | 26 | .772 | 192 | .297 | 115 | .467 | 118 | .480 | 34.6 | 5.4 | 4.81 | 4.36 |
| Reed Garrett | NYN | mr | 31 | .905 | 36 | .389 | 29 | .558 | 29 | .558 | 9.5 | 7.8 | 7.23 | 7.55 |
| Robert Gasser* | Atl | sp | 25 | .834 | 104 | .346 | 83 | .506 | 86 | .524 | 27.3 | 6.9 | 6.20 | 5.79 |
| Chris Gau | Oak | mr | 27 | .646 | 263 | .274 | 155 | .392 | 162 | .410 | 38.9 | 3.7 | 3.27 | 2.98 |
| Kevin Gausman | | sp | 33 | .675 | 635 | .288 | 426 | .427 | 430 | .431 | 105.5 | 3.9 | 3.48 | 3.14 |
| Domingo German | Pit | sp | 31 | .726 | 588 | .301 | 390 | .448 | 398 | .457 | 104.8 | 4.5 | 4.12 | 3.85 |
| Kyle Gibson | Min | sp | 36 | .743 | 577 | .298 | 356 | .455 | 361 | .461 | 96.3 | 4.7 | 4.27 | 4.11 |
| Luis Gil | | sp | 26 | .708 | 309 | .278 | 255 | .461 | 258 | .467 | 65.4 | 4.6 | 4.16 | 4.00 |
| Logan Gilbert | Ari | sp | 27 | .648 | 683 | .290 | 403 | .397 | 411 | .405 | 100.2 | 3.6 | 3.27 | 2.92 |
| Keagan Gillies | Cin | mr | 26 | 1.216 | 12 | .333 | 15 | .833 | 15 | .833 | 5.2 | 11.6 | 10.48 | 8.13 |
| Kevin Ginkel | | mr | 30 | .602 | 168 | .238 | 115 | .394 | 116 | .397 | 24.1 | 3.0 | 2.67 | 2.56 |
| J.T. Ginn | Pit | sp | 25 | .868 | 40 | .375 | 35 | .547 | 35 | .547 | 9.2 | 5.4 | 4.78 | 5.68 |
| Tyler Glasnow | Sea | sp | 30 | .632 | 308 | .263 | 212 | .412 | 212 | .412 | 49.9 | 3.5 | 3.19 | 2.65 |
| Woo-suk Go | Mil | mr | 25 | .758 | 99 | .253 | 83 | .491 | 86 | .509 | 20.5 | 4.5 | 4.12 | 4.25 |
| Yoendrys Gomez | NYA | sp | 24 | 1.000 | 58 | .345 | 58 | .644 | 59 | .656 | 18.8 | 8.6 | 7.89 | 7.91 |
| Marco Gonzales* | ChA | sp | 32 | .955 | 48 | .396 | 36 | .581 | 36 | .581 | 12.4 | 8.6 | 7.76 | 7.98 |
| Colton Gordon* | Phi | sp | 25 | .652 | 146 | .288 | 76 | .384 | 78 | .394 | 20.3 | 3.9 | 3.45 | 3.41 |
| MacKenzie Gore* | NYN | sp | 25 | .615 | 514 | .251 | 344 | .400 | 346 | .402 | 70.3 | 2.9 | 2.61 | 2.54 |
| Anthony Gose* | Hou | mr | 33 | .665 | 132 | .212 | 115 | .439 | 119 | .454 | 26.1 | 3.7 | 3.41 | 3.50 |
| Gordon Graceffo | | sp | 24 | .737 | 265 | .309 | 158 | .440 | 161 | .448 | 44.2 | 4.8 | 4.44 | 4.65 |
| Brusdar Graterol | Bal | mr | 25 | .559 | 51 | .255 | 26 | .347 | 26 | .347 | 4.9 | 2.2 | 2.04 | 1.92 |
| Jon Gray | Oak | sp | 32 | .663 | 446 | .258 | 285 | .408 | 300 | .430 | 68.8 | 3.6 | 3.26 | 3.23 |
| Sonny Gray | | sp | 34 | .706 | 482 | .299 | 294 | .429 | 301 | .439 | 79.4 | 4.4 | 4.01 | 3.86 |
| Chad Green | ChN | mr | 33 | .550 | 140 | .264 | 79 | .343 | 81 | .352 | 16.3 | 2.5 | 2.23 | 1.82 |
| Hunter Greene | Col | sp | 24 | .755 | 326 | .362 | 282 | .472 | 288 | .482 | 82.0 | 5.4 | 4.91 | 4.48 |
| Michael Grove | | sp | 27 | .657 | 136 | .294 | 87 | .410 | 89 | .420 | 20.2 | 3.4 | 3.12 | 2.74 |
| Luis Guerrero | Tor | mr | 23 | .731 | 66 | .364 | 41 | .427 | 42 | .438 | 11.9 | 5.0 | 4.58 | 4.36 |
| Tyson Guerrero* | Sea | sp | 25 | .391 | 13 | .154 | 6 | .261 | 6 | .261 | 0.3 | 0.3 | 0.30 | 0.73 |
| Josh Hader* | | cl | 30 | .484 | 125 | .288 | 68 | .291 | 70 | .299 | 12.4 | 1.8 | 1.66 | 1.62 |
| Justin Hagenman | Oak | mr | 27 | .751 | 225 | .307 | 144 | .460 | 145 | .463 | 42.4 | 5.4 | 4.84 | 4.77 |
| DL Hall* | Bal | mr | 25 | .710 | 253 | .316 | 223 | .452 | 228 | .462 | 57.6 | 4.5 | 4.06 | 4.23 |
| Ian Hamilton | Tex | mr | 29 | .519 | 162 | .222 | 91 | .327 | 95 | .342 | 18.6 | 2.3 | 2.17 | 1.74 |
| Emerson Hancock | Sea | sp | 25 | .743 | 520 | .342 | 330 | .440 | 341 | .455 | 92.2 | 4.7 | 4.24 | 4.20 |
| Hayden Harris* | | mr | 25 | .754 | 102 | .343 | 70 | .455 | 72 | .468 | 19.4 | 5.0 | 4.49 | 4.14 |
| Kyle Harrison* | Atl | sp | 22 | .749 | 338 | .305 | 277 | .478 | 280 | .483 | 74.7 | 5.1 | 4.64 | 4.86 |
| Grant Hartwig | NYN | mr | 26 | .775 | 44 | .295 | 34 | .472 | 36 | .500 | 9.8 | 5.8 | 5.19 | 5.36 |
| Hunter Harvey | | mr | 29 | .541 | 151 | .245 | 70 | .333 | 70 | .333 | 13.6 | 2.2 | 2.00 | 1.68 |
| Andrew Heaney* | KC | sp | 33 | .784 | 256 | .316 | 200 | .485 | 207 | .502 | 55.3 | 5.1 | 4.63 | 4.49 |
| Ryan Helsley | | cl | 29 | .676 | 160 | .306 | 119 | .436 | 119 | .436 | 28.7 | 3.9 | 3.43 | 2.94 |
| Markevian Hence | SF | sp | 21 | .797 | 505 | .291 | 354 | .503 | 360 | .511 | 99.8 | 5.5 | 4.95 | 4.45 |
| Ryan Hennen* | Det | mr | 26 | .639 | 155 | .258 | 83 | .379 | 88 | .402 | 20.1 | 3.3 | 3.01 | 2.79 |
| Ronny Henriquez | Was | mr | 24 | .787 | 227 | .308 | 150 | .475 | 155 | .491 | 44.1 | 5.5 | 4.84 | 4.65 |
| Cole Henry | Pit | sp | 24 | .726 | 283 | .311 | 193 | .435 | 202 | .455 | 54.6 | 4.7 | 4.28 | 4.16 |
| Tommy Henry* | LAA | sp | 26 | .627 | 247 | .267 | 129 | .375 | 133 | .387 | 32.3 | 3.5 | 3.20 | 2.98 |
| Sam Hentges* | Tex | mr | 27 | .694 | 91 | .242 | 65 | .455 | 65 | .455 | 14.5 | 3.6 | 3.21 | 3.12 |
| Carlos Hernandez | Tex | mr | 27 | .714 | 13 | .154 | 7 | .500 | 7 | .500 | 1.0 | 2.3 | 2.21 | 2.49 |
| Daysbel Hernandez | NYN | mr | 27 | .984 | 5 | .600 | 5 | .556 | 5 | .556 | 2.2 | 15.1 | 13.64 | 16.21 |
| Jakob Hernandez* | Oak | mr | 28 | .867 | 14 | .429 | 12 | .522 | 12 | .522 | 3.7 | 6.6 | 5.93 | 7.46 |
| Jose Hernandez* | Was | mr | 26 | .619 | 61 | .328 | 40 | .374 | 41 | .383 | 9.8 | 3.5 | 3.17 | 3.17 |
| Tim Herrin* | Sea | mr | 27 | .643 | 206 | .248 | 139 | .416 | 139 | .416 | 30.1 | 3.2 | 2.92 | 2.77 |
| Jordan Hicks | SF | mr | 27 | .832 | 259 | .355 | 236 | .511 | 244 | .528 | 72.0 | 6.5 | 5.89 | 6.02 |
| Porter Hodge | Was | mr | 23 | .739 | 220 | .273 | 162 | .467 | 166 | .478 | 43.7 | 4.9 | 4.37 | 4.26 |
| Jeff Hoffman | | mr | 31 | .797 | 181 | .381 | 158 | .495 | 161 | .505 | 48.2 | 6.1 | 5.57 | 5.28 |
| Gunnar Hoglund | Oak | sp | 24 | .744 | 83 | .337 | 51 | .440 | 52 | .448 | 15.5 | 5.2 | 4.59 | 4.58 |
| Colin Holderman | Phi | mr | 28 | .693 | 229 | .266 | 164 | .436 | 171 | .455 | 40.5 | 4.0 | 3.65 | 3.36 |
| Grant Holman | KC | mr | 24 | .793 | 155 | .361 | 113 | .481 | 115 | .489 | 32.3 | 5.4 | 4.87 | 5.18 |
| Clay Holmes | Oak | cl | 31 | .622 | 167 | .275 | 111 | .385 | 115 | .399 | 25.0 | 3.1 | 2.83 | 2.72 |
| Grant Holmes | Mia | mr | 28 | .635 | 112 | .268 | 75 | .403 | 76 | .409 | 16.4 | 3.1 | 2.81 | 2.83 |
| Tyler Holton* | | mr | 28 | .591 | 261 | .261 | 131 | .354 | 135 | .365 | 30.0 | 2.9 | 2.59 | 2.37 |
| Brent Honeywell | Col | mr | 29 | .670 | 143 | .266 | 78 | .406 | 80 | .417 | 19.4 | 3.8 | 3.41 | 3.32 |
| Tanner Houck | LAN | sp | 28 | .749 | 502 | .295 | 375 | .465 | 388 | .481 | 100.0 | 4.7 | 4.29 | 4.35 |
| Spencer Howard | | sp | 27 | .846 | 85 | .318 | 80 | .548 | 81 | .555 | 23.2 | 6.4 | 5.74 | 5.77 |
| Bryan Hudson* | Col | mr | 27 | .906 | 138 | .399 | 126 | .553 | 129 | .566 | 41.9 | 7.8 | 7.12 | 7.02 |
| Daniel Hudson | | mr | 37 | .749 | 121 | .264 | 97 | .490 | 98 | .495 | 24.5 | 4.6 | 4.18 | 4.02 |
| Brandon Hughes* | NYN | mr | 28 | .462 | 52 | .135 | 24 | .308 | 25 | .321 | 3.8 | 1.6 | 1.48 | 1.24 |
| Kyle Hurt | Bos | sp | 26 | .712 | 90 | .256 | 74 | .465 | 75 | .472 | 19.3 | 4.6 | 4.11 | 3.73 |
| Brant Hurter* | ChN | sp | 25 | .722 | 593 | .292 | 360 | .440 | 369 | .451 | 94.3 | 4.3 | 3.86 | 3.70 |
| Raisel Iglesias | | cl | 34 | .635 | 182 | .341 | 109 | .382 | 110 | .386 | 25.9 | 3.3 | 2.96 | 2.49 |
| Shota Imanaga* | SD | sp | 30 | .673 | 461 | .282 | 294 | .415 | 304 | .429 | 72.1 | 3.7 | 3.36 | 3.14 |
| Jairo Iriarte | Col | sp | 22 | 1.012 | 123 | .390 | 122 | .607 | 130 | .647 | 43.2 | 9.4 | 8.75 | 9.20 |
| Cole Irvin* | ChA | sp | 30 | .809 | 629 | .316 | 422 | .498 | 432 | .509 | 120.1 | 5.4 | 4.93 | 4.81 |
| Jake Irvin | | sp | 27 | .736 | 331 | .248 | 230 | .458 | 241 | .480 | 57.0 | 4.2 | 3.83 | 4.03 |
| Jay Jackson | Mia | mr | 36 | .851 | 135 | .311 | 127 | .557 | 128 | .561 | 37.7 | 6.5 | 5.95 | 5.18 |
| Alek Jacob | Pit | mr | 26 | .549 | 55 | .200 | 25 | .321 | 28 | .359 | 5.0 | 2.2 | 2.01 | 1.89 |
| Kenley Jansen | | cl | 36 | .918 | 146 | .356 | 154 | .586 | 157 | .597 | 48.5 | 7.7 | 6.77 | 6.61 |
| Bryce Jarvis | LAA | sp | 26 | .710 | 188 | .213 | 125 | .472 | 125 | .472 | 29.8 | 4.1 | 3.71 | 3.26 |
| Cristian Javier | Min | sp | 27 | .690 | 90 | .289 | 67 | .447 | 67 | .447 | 17.2 | 4.3 | 3.87 | 3.41 |
| Griffin Jax | Min | mr | 29 | .637 | 149 | .302 | 80 | .360 | 87 | .392 | 20.3 | 3.4 | 3.04 | 2.96 |
| Joe Jimenez | NYN | mr | 29 | .690 | 153 | .261 | 124 | .444 | 128 | .459 | 30.6 | 4.0 | 3.63 | 3.40 |
| Jackson Jobe | SF | sp | 21 | .799 | 361 | .313 | 258 | .490 | 263 | .499 | 77.6 | 5.9 | 5.28 | 5.11 |
| Pierce Johnson | Mil | mr | 33 | .679 | 75 | .267 | 61 | .442 | 62 | .449 | 14.8 | 4.0 | 3.60 | 3.62 |
| Seth Johnson | Phi | sp | 25 | .738 | 242 | .285 | 182 | .469 | 187 | .482 | 50.0 | 5.0 | 4.62 | 4.14 |
| Jared Jones | Bos | sp | 22 | .681 | 379 | .277 | 242 | .422 | 248 | .433 | 61.3 | 4.0 | 3.63 | 3.51 |
| Hayden Juenger | Hou | mr | 23 | .650 | 190 | .274 | 117 | .398 | 121 | .412 | 27.0 | 3.4 | 3.14 | 3.49 |
| Jakob Junis | Det | mr | 31 | .780 | 71 | .268 | 46 | .495 | 47 | .505 | 10.8 | 4.1 | 3.82 | 3.50 |
| Tommy Kahnle | Oak | mr | 34 | .740 | 41 | .317 | 35 | .486 | 35 | .486 | 8.1 | 4.1 | 3.80 | 3.40 |
| Mitch Keller | | sp | 28 | .705 | 605 | .301 | 383 | .426 | 397 | .441 | 96.5 | 3.9 | 3.58 | 3.53 |
| Antoine Kelly* | Atl | mr | 24 | .767 | 38 | .395 | 27 | .429 | 29 | .460 | 8.5 | 5.8 | 5.19 | 6.23 |
| Joe Kelly | LAA | mr | 36 | .778 | 47 | .340 | 38 | .469 | 40 | .494 | 10.3 | 5.0 | 4.48 | 4.82 |
| Kevin Kelly | | mr | 26 | .614 | 208 | .327 | 104 | .329 | 115 | .364 | 28.8 | 3.5 | 3.14 | 3.06 |
| Merrill Kelly | Det | sp | 35 | .582 | 308 | .260 | 156 | .354 | 158 | .358 | 36.6 | 3.0 | 2.70 | 2.30 |
| Michael Kelly | Bal | mr | 31 | .820 | 91 | .352 | 82 | .512 | 83 | .519 | 21.3 | 5.3 | 4.74 | 5.95 |
| Zack Kelly | Bal | mr | 29 | .827 | 86 | .256 | 80 | .519 | 84 | .545 | 24.2 | 6.6 | 5.94 | 6.19 |
| Orion Kerkering | Bos | mr | 23 | .702 | 212 | .316 | 149 | .437 | 152 | .446 | 39.6 | 4.3 | 3.94 | 3.52 |
| Ray Kerr* | LAA | mr | 29 | .566 | 16 | .375 | 10 | .313 | 11 | .344 | 2.7 | 3.5 | 3.11 | 3.64 |
| Brett Kerry | NYA | sp | 25 | .901 | 285 | .323 | 222 | .561 | 224 | .566 | 72.3 | 7.5 | 6.83 | 6.84 |
| Clayton Kershaw* | LAA | sp | 36 | .640 | 101 | .307 | 67 | .409 | 67 | .409 | 15.7 | 3.4 | 3.10 | 2.47 |
| Yusei Kikuchi* | NYN | sp | 33 | .669 | 525 | .253 | 359 | .434 | 362 | .438 | 78.4 | 3.3 | 3.04 | 2.97 |
| Craig Kimbrel | | cl | 36 | .857 | 131 | .305 | 119 | .541 | 122 | .555 | 36.4 | 6.8 | 6.05 | 5.85 |
| John King* | StL | mr | 29 | .656 | 204 | .260 | 103 | .395 | 106 | .406 | 25.8 | 3.7 | 3.33 | 2.96 |
| Michael King | Tam | mr | 29 | .743 | 418 | .299 | 357 | .476 | 367 | .489 | 92.1 | 4.6 | 4.14 | 4.00 |
| George Kirby | Sea | sp | 26 | .726 | 621 | .319 | 375 | .440 | 380 | .446 | 101.7 | 4.4 | 4.08 | 3.81 |
| Andrew Kittredge | ChN | mr | 34 | .792 | 57 | .263 | 37 | .514 | 37 | .514 | 9.3 | 4.7 | 4.27 | 3.77 |
| Will Klein | Mia | mr | 24 | .636 | 33 | .242 | 19 | .373 | 21 | .412 | 4.7 | 3.6 | 3.20 | 3.68 |
| Jared Koenig* | Tam | mr | 30 | .861 | 33 | .212 | 29 | .558 | 31 | .596 | 7.3 | 5.2 | 4.70 | 4.87 |
| Michael Kopech | SF | sp | 28 | .889 | 252 | .317 | 226 | .555 | 232 | .570 | 75.2 | 7.9 | 7.25 | 6.95 |
| Dean Kremer | Det | sp | 28 | .649 | 619 | .260 | 371 | .408 | 377 | .415 | 85.5 | 3.4 | 3.03 | 2.81 |
| Alex Lange | LAN | cl | 28 | .594 | 148 | .304 | 93 | .371 | 93 | .371 | 21.0 | 3.1 | 2.79 | 2.45 |
| Jake Latz* | Phi | mr | 28 | .903 | 19 | .368 | 21 | .600 | 21 | .600 | 5.2 | 5.4 | 4.87 | 5.66 |
| Nate Lavender* | ChA | mr | 24 | .669 | 180 | .317 | 131 | .411 | 136 | .426 | 32.8 | 3.9 | 3.53 | 3.49 |
| Justin Lawrence | Bos | mr | 29 | .584 | 169 | .249 | 99 | .355 | 106 | .380 | 22.7 | 3.1 | 2.81 | 2.92 |
| Max Lazar | NYA | mr | 25 | .765 | 353 | .303 | 223 | .471 | 224 | .474 | 63.9 | 5.2 | 4.68 | 4.44 |
| Jose Leclerc | Pit | mr | 30 | .778 | 169 | .278 | 144 | .503 | 146 | .510 | 37.6 | 5.1 | 4.66 | 4.39 |
| Dylan Lee* | | mr | 29 | .600 | 191 | .288 | 106 | .366 | 107 | .369 | 25.2 | 3.2 | 2.85 | 2.48 |
| Jack Leiter | SF | sp | 24 | .856 | 300 | .327 | 269 | .543 | 272 | .549 | 83.8 | 6.9 | 6.29 | 5.91 |
| Mark Leiter | Bos | mr | 33 | .558 | 191 | .220 | 109 | .346 | 117 | .371 | 23.9 | 2.7 | 2.40 | 2.06 |
| Matthew Liberatore* | | sp | 24 | .702 | 347 | .305 | 219 | .429 | 223 | .437 | 57.4 | 4.3 | 3.82 | 3.65 |
| Yu-Min Lin* | Bal | sp | 20 | .656 | 523 | .285 | 332 | .401 | 345 | .417 | 82.9 | 3.7 | 3.42 | 3.32 |
| Zack Littell | Cle | mr | 28 | .693 | 459 | .292 | 275 | .422 | 283 | .434 | 72.1 | 4.1 | 3.78 | 3.46 |
| Brendon Little* | LAN | mr | 27 | .744 | 249 | .285 | 164 | .459 | 167 | .468 | 47.3 | 5.3 | 4.83 | 4.44 |
| Luke Little* | Hou | mr | 23 | .771 | 66 | .379 | 63 | .488 | 64 | .496 | 18.2 | 5.8 | 5.20 | 4.95 |
| Ben Lively | | sp | 32 | .696 | 420 | .288 | 260 | .428 | 266 | .438 | 67.2 | 4.1 | 3.77 | 3.59 |
| Mauricio Llovera | StL | mr | 28 | .763 | 119 | .311 | 77 | .456 | 81 | .479 | 23.3 | 5.3 | 4.84 | 4.38 |
| Jonathan Loaisiga | Ari | mr | 29 | .718 | 26 | .308 | 19 | .463 | 19 | .463 | 4.0 | 3.4 | 3.04 | 3.20 |
| Nick Lodolo* | | sp | 26 | .677 | 142 | .289 | 98 | .430 | 100 | .439 | 23.5 | 3.7 | 3.42 | 2.90 |
| Pablo Lopez | Tex | sp | 28 | .644 | 622 | .286 | 384 | .392 | 399 | .407 | 95.5 | 3.6 | 3.23 | 2.91 |
| Reynaldo Lopez | LAA | mr | 30 | .617 | 101 | .287 | 70 | .393 | 70 | .393 | 16.7 | 3.4 | 3.12 | 2.79 |
| Michael Lorenzen | LAA | sp | 32 | .653 | 262 | .248 | 148 | .401 | 153 | .415 | 31.8 | 3.1 | 2.80 | 2.95 |
| Ryan Loutos | Mia | mr | 25 | 1.571 | 4 | .500 | 7 | 1.000 | 7 | 1.000 | 3.6 | 32.2 | 28.97 | 32.12 |
| Richard Lovelady* | | mr | 28 | .708 | 80 | .262 | 51 | .432 | 54 | .458 | 12.2 | 3.8 | 3.40 | 3.47 |
| Seth Lugo | NYN | sp | 34 | .631 | 610 | .246 | 339 | .394 | 345 | .401 | 78.8 | 3.3 | 2.97 | 2.70 |
| Jesus Luzardo* | Cle | sp | 26 | .679 | 238 | .324 | 161 | .417 | 164 | .425 | 41.1 | 3.9 | 3.60 | 3.30 |
| Daniel Lynch* | Phi | sp | 27 | .504 | 15 | .267 | 7 | .304 | 7 | .304 | 1.8 | 3.0 | 2.69 | 2.60 |
| Lance Lynn | LAN | sp | 37 | .673 | 580 | .271 | 351 | .415 | 362 | .428 | 89.8 | 3.9 | 3.57 | 3.09 |
| Adam Macko* | | sp | 23 | .872 | 179 | .324 | 163 | .560 | 166 | .570 | 49.3 | 6.9 | 6.30 | 5.89 |
| Kenta Maeda | Mil | sp | 36 | .481 | 39 | .231 | 15 | .288 | 15 | .288 | 3.1 | 2.1 | 1.96 | 1.41 |
| Tyler Mahle | Ari | sp | 29 | .382 | 34 | .176 | 13 | .250 | 13 | .250 | 1.8 | 1.1 | 1.03 | 0.97 |
| Anthony Maldonado | Tor | mr | 26 | .728 | 245 | .331 | 179 | .446 | 184 | .459 | 47.9 | 4.6 | 4.25 | 4.18 |
| Matt Manning | Mia | sp | 26 | .586 | 272 | .228 | 141 | .371 | 142 | .374 | 31.2 | 2.9 | 2.64 | 2.21 |
| Alek Manoah | Sea | sp | 26 | .734 | 58 | .362 | 42 | .452 | 42 | .452 | 11.7 | 4.9 | 4.38 | 4.06 |
| Joe Mantiply* | KC | mr | 33 | .630 | 148 | .291 | 85 | .385 | 87 | .394 | 17.0 | 2.7 | 2.38 | 2.42 |
| Ron Marinaccio | ChA | mr | 28 | .810 | 207 | .324 | 173 | .499 | 178 | .513 | 52.8 | 6.3 | 5.62 | 5.90 |
| German Marquez | Bos | sp | 29 | .333 | 43 | .163 | 13 | .210 | 13 | .210 | 1.6 | 0.8 | 0.77 | 0.71 |
| Alec Marsh | | sp | 26 | .782 | 279 | .344 | 205 | .481 | 209 | .491 | 58.5 | 5.4 | 4.85 | 4.60 |
| Chris Martin | ChN | mr | 38 | .588 | 93 | .258 | 45 | .357 | 46 | .365 | 10.0 | 2.7 | 2.45 | 1.75 |
| Davis Martin | SD | sp | 27 | .857 | 14 | .214 | 14 | .583 | 14 | .583 | 4.1 | 6.9 | 6.64 | 6.73 |
| Justin Martinez | Tex | mr | 22 | .748 | 129 | .279 | 124 | .482 | 128 | .498 | 32.7 | 5.2 | 4.73 | 4.94 |
| Nick Martinez | Mil | mr | 33 | .692 | 561 | .301 | 361 | .425 | 370 | .435 | 91.6 | 4.0 | 3.61 | 3.38 |
| Seth Martinez | Hou | mr | 29 | .780 | 312 | .330 | 220 | .465 | 230 | .486 | 64.9 | 5.4 | 4.84 | 4.80 |
| Phil Maton | | mr | 31 | .724 | 166 | .295 | 130 | .438 | 140 | .471 | 33.6 | 4.3 | 3.93 | 4.30 |
| Yuki Matsui* | NYN | mr | 28 | .534 | 112 | .277 | 74 | .339 | 76 | .349 | 14.8 | 2.5 | 2.27 | 2.41 |
| Steven Matz* | | sp | 33 | .623 | 125 | .272 | 69 | .365 | 74 | .392 | 17.1 | 3.4 | 3.11 | 2.90 |
| Tyler Matzek* | SD | mr | 33 | .610 | 37 | .216 | 27 | .380 | 29 | .408 | 6.5 | 3.4 | 3.23 | 3.18 |
| Tim Mayza* | | mr | 32 | .697 | 62 | .339 | 33 | .388 | 35 | .412 | 10.0 | 4.6 | 4.11 | 3.85 |
| James McArthur | Det | mr | 27 | .950 | 29 | .414 | 20 | .526 | 22 | .579 | 7.2 | 7.8 | 7.00 | 7.15 |
| Chayce McDermott | LAN | sp | 25 | .638 | 452 | .252 | 290 | .403 | 298 | .414 | 67.9 | 3.5 | 3.17 | 2.91 |
| Griff McGarry | Bal | sp | 25 | .738 | 157 | .318 | 120 | .458 | 123 | .469 | 33.4 | 5.4 | 4.86 | 5.17 |
| Scott McGough | Hou | mr | 34 | .916 | 67 | .388 | 67 | .588 | 67 | .588 | 20.6 | 7.4 | 6.58 | 6.77 |
| Michael McGreevy | ChA | sp | 23 | .683 | 77 | .286 | 43 | .422 | 43 | .422 | 10.5 | 3.8 | 3.39 | 3.15 |
| Evan McKendry | SD | sp | 26 | .676 | 240 | .275 | 124 | .396 | 131 | .419 | 32.6 | 3.9 | 3.51 | 3.23 |
| Triston McKenzie | | sp | 26 | .775 | 628 | .299 | 429 | .485 | 433 | .490 | 119.9 | 5.2 | 4.69 | 4.33 |
| John McMillon | Pit | mr | 26 | .869 | 37 | .378 | 37 | .536 | 37 | .536 | 12.5 | 8.4 | 7.41 | 6.61 |
| John Means* | Tex | sp | 31 | .551 | 37 | .243 | 16 | .302 | 18 | .340 | 4.4 | 3.0 | 2.73 | 2.04 |
| Nick Mears | | mr | 27 | .758 | 25 | .200 | 19 | .514 | 19 | .514 | 4.4 | 4.8 | 4.47 | 5.24 |
| Trevor Megill | | mr | 30 | .652 | 86 | .267 | 68 | .407 | 72 | .431 | 17.6 | 4.0 | 3.72 | 3.33 |
| Tylor Megill | NYN | sp | 28 | .381 | 17 | .235 | 4 | .190 | 4 | .190 | 0.9 | 1.4 | 1.23 | 1.01 |
| Juan M. Mejia | Mia | mr | 23 | .720 | 26 | .192 | 19 | .500 | 19 | .500 | 4.1 | 3.8 | 3.32 | 2.85 |
| Cristian Mena | Col | sp | 21 | .826 | 374 | .305 | 290 | .524 | 294 | .532 | 83.6 | 5.9 | 5.39 | 5.21 |
| Michael Mercado | NYA | mr | 25 | .726 | 159 | .327 | 109 | .447 | 109 | .447 | 29.2 | 4.6 | 4.22 | 4.43 |
| Julian Merryweather | | mr | 32 | .540 | 42 | .333 | 25 | .325 | 25 | .325 | 5.7 | 2.6 | 2.36 | 1.99 |
| Max Meyer | ChA | sp | 25 | .735 | 486 | .292 | 347 | .466 | 350 | .470 | 87.1 | 4.4 | 3.99 | 3.99 |
| Miles Mikolas | StL | sp | 35 | .622 | 722 | .262 | 356 | .377 | 362 | .383 | 85.6 | 3.3 | 2.95 | 2.49 |
| Bobby Miller | Bal | sp | 25 | .609 | 496 | .292 | 266 | .360 | 273 | .370 | 64.2 | 3.2 | 2.85 | 2.78 |
| Bryce Miller | | sp | 25 | .653 | 684 | .278 | 382 | .395 | 393 | .406 | 93.7 | 3.5 | 3.24 | 3.04 |
| Erik Miller* | | mr | 26 | .888 | 58 | .397 | 75 | .564 | 77 | .579 | 24.0 | 7.8 | 7.03 | 6.85 |
| Mason Miller | Bos | mr | 25 | .463 | 171 | .199 | 91 | .294 | 96 | .310 | 16.6 | 1.9 | 1.69 | 1.56 |
| Tyson Miller | | mr | 28 | .842 | 94 | .372 | 71 | .504 | 74 | .525 | 22.9 | 6.6 | 6.11 | 5.76 |
| Hoby Milner* | Cin | mr | 33 | .617 | 109 | .275 | 64 | .368 | 68 | .391 | 14.3 | 2.9 | 2.64 | 2.67 |
| A.J. Minter* | Was | mr | 30 | .796 | 67 | .299 | 56 | .500 | 58 | .518 | 16.5 | 5.7 | 5.34 | 4.73 |
| Andrew Misiaszek* | Cin | mr | 26 | .805 | 19 | .316 | 15 | .517 | 15 | .517 | 3.8 | 5.4 | 4.89 | 5.36 |
| Jacob Misiorowski | Tex | sp | 22 | .809 | 151 | .331 | 133 | .475 | 147 | .525 | 44.2 | 6.9 | 6.17 | 6.17 |
| Casey Mize | | sp | 27 | .653 | 393 | .275 | 221 | .394 | 230 | .410 | 53.9 | 3.5 | 3.16 | 2.93 |
| Sam Moll* | Tor | mr | 32 | .693 | 40 | .275 | 28 | .459 | 28 | .459 | 6.6 | 3.9 | 3.48 | 2.69 |
| Frankie Montas | ChN | sp | 31 | .713 | 173 | .341 | 113 | .417 | 119 | .439 | 33.9 | 4.9 | 4.45 | 4.27 |
| Keider Montero | | sp | 23 | .603 | 51 | .255 | 24 | .353 | 25 | .368 | 6.2 | 3.3 | 3.19 | 2.99 |
| Jordan Montgomery* | | sp | 31 | .664 | 596 | .292 | 348 | .402 | 357 | .413 | 86.9 | 3.7 | 3.35 | 3.07 |
| Matt Moore* | Min | mr | 35 | .727 | 183 | .306 | 133 | .457 | 134 | .460 | 35.5 | 4.6 | 4.15 | 4.09 |
| Francisco Morales | LAN | mr | 24 | .570 | 141 | .270 | 82 | .353 | 84 | .362 | 17.3 | 2.7 | 2.42 | 2.55 |
| Adrian Morejon* | | mr | 25 | .760 | 124 | .315 | 86 | .467 | 88 | .478 | 25.1 | 5.4 | 4.96 | 4.65 |
| Eli Morgan | Det | mr | 28 | .563 | 324 | .262 | 174 | .347 | 179 | .357 | 38.3 | 2.7 | 2.44 | 1.79 |
| Charlie Morton | SD | sp | 40 | .666 | 532 | .276 | 359 | .412 | 374 | .429 | 83.0 | 3.5 | 3.19 | 3.27 |
| Kyle Muller* | Tor | sp | 26 | .817 | 83 | .398 | 60 | .492 | 60 | .492 | 18.1 | 6.0 | 5.36 | 5.62 |
| Andres Munoz | Sea | mr | 25 | .658 | 156 | .353 | 125 | .401 | 130 | .417 | 33.2 | 4.0 | 3.62 | 3.27 |
| Roddery Munoz | Tex | sp | 24 | .774 | 13 | .308 | 6 | .429 | 6 | .429 | 1.9 | 5.3 | 4.74 | 4.29 |
| Ryan Murphy | SF | sp | 24 | .758 | 213 | .296 | 138 | .462 | 142 | .475 | 38.8 | 5.0 | 4.60 | 4.36 |
| Joe Musgrove | | sp | 31 | .614 | 334 | .260 | 169 | .343 | 190 | .386 | 43.8 | 3.3 | 2.96 | 2.79 |
| Tobias Myers | | sp | 25 | .471 | 36 | .194 | 16 | .302 | 16 | .302 | 2.5 | 1.5 | 1.36 | 1.42 |
| Andrew Nardi* | Atl | mr | 25 | .767 | 153 | .255 | 140 | .509 | 141 | .513 | 35.9 | 5.0 | 4.39 | 4.11 |
| Nick Nastrini | SD | sp | 24 | .870 | 15 | .467 | 12 | .522 | 12 | .522 | 4.2 | 7.5 | 6.76 | 6.56 |
| Packy Naughton* | Was | sp | 28 | .715 | 233 | .270 | 144 | .453 | 145 | .456 | 34.5 | 3.9 | 3.54 | 3.17 |
| Jack Neely | | mr | 24 | .782 | 236 | .314 | 201 | .490 | 206 | .502 | 56.3 | 5.4 | 4.92 | 4.74 |
| Kyle Nelson* | Atl | mr | 27 | .681 | 20 | .350 | 11 | .379 | 12 | .414 | 3.4 | 4.6 | 4.38 | 3.38 |
| Ryne Nelson | Cin | sp | 26 | .726 | 457 | .293 | 278 | .442 | 285 | .453 | 72.9 | 4.3 | 3.90 | 3.78 |
| Hector Neris | Cin | mr | 35 | .547 | 154 | .227 | 96 | .350 | 99 | .361 | 19.9 | 2.6 | 2.29 | 2.09 |
| Kyle Nicolas | Atl | sp | 25 | .915 | 151 | .325 | 142 | .568 | 148 | .592 | 46.0 | 7.7 | 7.03 | 7.23 |
| Aaron Nola | Cle | sp | 31 | .615 | 645 | .291 | 362 | .374 | 370 | .382 | 84.7 | 3.1 | 2.81 | 2.35 |
| Dedniel Nunez | Tex | mr | 28 | .702 | 239 | .259 | 169 | .451 | 170 | .453 | 44.4 | 4.6 | 4.12 | 3.90 |
| Bailey Ober | | sp | 28 | .673 | 424 | .278 | 257 | .420 | 260 | .425 | 62.5 | 3.7 | 3.36 | 3.09 |
| Pierson Ohl | KC | sp | 24 | .727 | 645 | .310 | 371 | .441 | 376 | .447 | 101.3 | 4.5 | 4.13 | 3.78 |
| Shohei Ohtani | Tex | dh | 29 | .683 | 54 | .278 | 34 | .415 | 36 | .439 | 8.8 | 4.0 | 3.57 | 3.26 |
| Steven Okert* | KC | mr | 32 | .857 | 151 | .338 | 139 | .537 | 144 | .556 | 40.3 | 6.1 | 5.45 | 5.54 |
| Mat Olsen | NYN | mr | 23 | .676 | 270 | .259 | 173 | .413 | 182 | .434 | 44.3 | 3.9 | 3.59 | 3.59 |
| Reese Olson | | sp | 24 | .840 | 265 | .336 | 206 | .522 | 208 | .527 | 62.2 | 6.3 | 5.69 | 5.51 |
| Kaleb Ort | Hou | mr | 32 | .850 | 14 | .500 | 13 | .500 | 13 | .500 | 4.0 | 7.6 | 6.86 | 10.22 |
| Luis L. Ortiz | | sp | 25 | .893 | 193 | .347 | 161 | .548 | 165 | .561 | 50.5 | 7.1 | 6.42 | 6.44 |
| Michel Otanez | Tex | mr | 26 | 2.279 | 9 | .778 | 32 | 1.333 | 33 | 1.375 | 21.3 | 95.6 | 86.08 | 87.12 |
| Adam Ottavino | SD | mr | 38 | .776 | 135 | .407 | 98 | .450 | 101 | .463 | 29.5 | 5.6 | 5.04 | 5.34 |
| Chris Paddack | | sp | 28 | .601 | 366 | .260 | 205 | .371 | 211 | .382 | 47.1 | 3.0 | 2.74 | 2.32 |
| Emilio Pagan | ChA | mr | 33 | .500 | 105 | .190 | 51 | .319 | 53 | .331 | 9.9 | 2.2 | 1.94 | 1.59 |
| Daniel Palencia | Mia | mr | 24 | .250 | 7 | .143 | 1 | .125 | 1 | .125 | 0.1 | 0.5 | 0.61 | 0.57 |
| Andre Pallante | Min | mr | 25 | .790 | 318 | .302 | 210 | .492 | 212 | .496 | 57.5 | 5.2 | 4.68 | 4.45 |
| Carson Palmquist* | Ari | sp | 23 | .600 | 111 | .252 | 65 | .344 | 74 | .392 | 15.9 | 3.1 | 2.84 | 2.97 |
| Enoli Paredes | NYA | mr | 28 | .876 | 138 | .312 | 128 | .566 | 128 | .566 | 38.3 | 7.0 | 6.29 | 6.52 |
| Mitchell Parker* | Atl | sp | 24 | .835 | 386 | .332 | 315 | .529 | 317 | .533 | 89.5 | 6.0 | 5.38 | 5.05 |
| Joel Payamps | Cin | mr | 30 | .755 | 133 | .301 | 90 | .462 | 93 | .477 | 24.9 | 5.0 | 4.58 | 4.58 |
| Nate Pearson | | mr | 27 | .726 | 191 | .298 | 161 | .463 | 166 | .477 | 41.9 | 4.7 | 4.24 | 4.24 |
| Elvis Peguero | | mr | 27 | .652 | 160 | .281 | 100 | .400 | 104 | .416 | 23.9 | 3.5 | 3.16 | 2.92 |
| Walter Pennington* | | mr | 26 | .685 | 35 | .400 | 24 | .393 | 25 | .410 | 6.2 | 4.1 | 3.66 | 4.57 |
| Ryan Pepiot | | sp | 26 | .623 | 444 | .227 | 282 | .401 | 289 | .411 | 63.0 | 3.2 | 2.92 | 2.75 |
| Freddy Peralta | | sp | 28 | .684 | 525 | .290 | 367 | .426 | 378 | .439 | 94.8 | 4.2 | 3.77 | 3.56 |
| Wandy Peralta* | SD | mr | 32 | .519 | 71 | .225 | 41 | .342 | 41 | .342 | 8.0 | 2.5 | 2.26 | 2.19 |
| Cionel Perez* | Mil | mr | 28 | .277 | 8 | .125 | 3 | .200 | 3 | .200 | 0.3 | 0.7 | 0.62 | 0.75 |
| Martin Perez* | LAN | sp | 33 | .744 | 636 | .305 | 388 | .446 | 402 | .462 | 105.2 | 4.5 | 4.09 | 4.03 |
| Jack Perkins | Bal | sp | 26 | .587 | 52 | .231 | 29 | .367 | 30 | .380 | 6.0 | 2.8 | 2.52 | 2.63 |
| David Peterson* | Oak | sp | 28 | .694 | 338 | .296 | 229 | .430 | 236 | .444 | 58.3 | 4.1 | 3.74 | 3.53 |
| Brandon Pfaadt | Col | sp | 25 | .702 | 608 | .301 | 387 | .430 | 394 | .438 | 101.5 | 4.2 | 3.88 | 3.61 |
| Evan Phillips | Mil | cl | 29 | .681 | 137 | .285 | 90 | .421 | 94 | .439 | 22.7 | 3.9 | 3.47 | 2.85 |
| Nick Pivetta | Was | sp | 31 | .742 | 274 | .223 | 218 | .490 | 222 | .499 | 52.3 | 4.3 | 3.87 | 3.86 |
| Colin Poche* | Col | mr | 30 | .793 | 106 | .321 | 93 | .500 | 95 | .511 | 27.7 | 6.2 | 5.43 | 5.16 |
| Cade Povich* | Bos | sp | 24 | .766 | 453 | .289 | 332 | .482 | 342 | .496 | 90.8 | 5.0 | 4.59 | 4.29 |
| Ryan Pressly | Cin | cl | 35 | .571 | 176 | .284 | 94 | .342 | 96 | .349 | 20.0 | 2.6 | 2.35 | 2.20 |
| A.J. Puk* | LAN | mr | 29 | .127 | 15 | .067 | 3 | .094 | 3 | .094 | 0.1 | 0.1 | 0.12 | 0.15 |
| Jose Quijada* | Mia | mr | 28 | .709 | 20 | .100 | 18 | .514 | 18 | .514 | 4.1 | 4.3 | 4.02 | 3.65 |
| Jose Quintana* | Pit | sp | 35 | .692 | 450 | .307 | 275 | .424 | 279 | .430 | 71.0 | 4.1 | 3.67 | 3.36 |
| Cole Ragans* | Was | sp | 26 | .690 | 296 | .287 | 199 | .433 | 204 | .443 | 47.4 | 3.7 | 3.32 | 3.12 |
| Taylor Rashi | ChN | mr | 28 | .619 | 234 | .265 | 133 | .383 | 136 | .392 | 30.6 | 3.2 | 2.87 | 2.60 |
| Drew Rasmussen | Bos | sp | 28 | .524 | 152 | .243 | 73 | .322 | 74 | .326 | 15.4 | 2.4 | 2.13 | 1.84 |
| Robbie Ray* | StL | sp | 32 | .926 | 104 | .365 | 82 | .558 | 85 | .578 | 27.5 | 7.7 | 6.96 | 7.00 |
| Marco Raya | Mia | sp | 21 | .813 | 220 | .255 | 170 | .525 | 175 | .540 | 47.2 | 5.6 | 5.09 | 4.74 |
| Colin Rea | Mil | sp | 33 | .760 | 100 | .290 | 68 | .486 | 69 | .493 | 16.0 | 4.0 | 3.68 | 3.41 |
| Sean Reid-Foley | | mr | 28 | .725 | 28 | .464 | 21 | .404 | 22 | .423 | 6.8 | 5.9 | 5.03 | 6.21 |
| Sean Reynolds | Mia | mr | 26 | .720 | 17 | .176 | 11 | .440 | 12 | .480 | 3.1 | 4.9 | 4.37 | 4.09 |
| Trevor Richards | NYN | mr | 31 | .708 | 426 | .289 | 335 | .448 | 344 | .461 | 84.5 | 4.3 | 3.84 | 3.79 |
| Sem Robberse | Pit | sp | 22 | .669 | 561 | .292 | 312 | .404 | 318 | .411 | 81.4 | 3.9 | 3.56 | 3.28 |
| Ethan Roberts | Oak | mr | 26 | .644 | 160 | .294 | 87 | .369 | 94 | .398 | 21.5 | 3.4 | 3.02 | 2.81 |
| David Robertson | | cl | 39 | .838 | 84 | .310 | 67 | .515 | 70 | .538 | 20.3 | 6.2 | 5.59 | 5.37 |
| Nick Robertson | Cin | mr | 25 | .695 | 135 | .304 | 83 | .426 | 84 | .431 | 22.0 | 4.3 | 3.80 | 3.44 |
| Joe Rock* | Cle | sp | 23 | .620 | 338 | .257 | 194 | .383 | 201 | .397 | 43.9 | 3.1 | 2.79 | 2.56 |
| Carlos Rodon* | ChA | sp | 31 | .663 | 518 | .288 | 356 | .413 | 365 | .424 | 90.5 | 3.9 | 3.53 | 3.23 |
| Carlos F. Rodriguez | Tor | sp | 22 | .680 | 115 | .278 | 75 | .412 | 79 | .434 | 19.0 | 3.9 | 3.61 | 3.61 |
| Eduardo Rodriguez* | Min | sp | 31 | .782 | 152 | .349 | 101 | .465 | 103 | .475 | 29.7 | 5.4 | 4.95 | 5.27 |
| Grayson Rodriguez | Tex | sp | 24 | .649 | 359 | .262 | 238 | .410 | 245 | .422 | 54.7 | 3.4 | 3.05 | 2.85 |
| Manuel Rodriguez | Pit | mr | 27 | .716 | 25 | .280 | 18 | .462 | 18 | .462 | 4.3 | 4.3 | 3.62 | 3.67 |
| Randy Rodriguez | Hou | mr | 24 | .500 | 7 | .286 | 4 | .267 | 5 | .333 | 0.9 | 2.5 | 2.25 | 2.96 |
| Yariel Rodriguez | ChN | mr | 27 | .775 | 109 | .321 | 83 | .459 | 90 | .497 | 24.0 | 5.2 | 4.75 | 4.73 |
| Yerry Rodriguez | LAN | mr | 26 | .883 | 120 | .383 | 97 | .539 | 98 | .544 | 32.2 | 7.5 | 6.79 | 6.68 |
| Taylor Rogers* | Ari | mr | 33 | .450 | 113 | .257 | 52 | .264 | 54 | .274 | 7.4 | 1.2 | 1.08 | 1.24 |
| Trevor Rogers* | SF | sp | 26 | .769 | 315 | .337 | 228 | .475 | 232 | .483 | 65.3 | 5.2 | 4.72 | 4.30 |
| Tyler Rogers | StL | mr | 33 | .610 | 224 | .246 | 111 | .372 | 114 | .383 | 24.9 | 2.9 | 2.65 | 2.20 |
| Jordan Romano | Cle | cl | 31 | .596 | 49 | .224 | 36 | .400 | 36 | .400 | 6.0 | 2.2 | 2.06 | 1.92 |
| JoJo Romero* | | mr | 27 | .639 | 177 | .277 | 114 | .399 | 116 | .406 | 26.1 | 3.2 | 2.95 | 2.70 |
| Landen Roupp | | sp | 25 | .803 | 370 | .265 | 278 | .516 | 282 | .523 | 78.0 | 5.7 | 5.22 | 5.12 |
| Jackson Rutledge | SF | sp | 25 | .773 | 260 | .323 | 159 | .454 | 166 | .474 | 50.6 | 5.8 | 5.30 | 4.71 |
| Joe Ryan | Mia | sp | 28 | .627 | 476 | .252 | 284 | .387 | 295 | .402 | 66.3 | 3.2 | 2.95 | 2.65 |
| Andrew Saalfrank* | Mia | mr | 26 | .608 | 98 | .255 | 61 | .384 | 63 | .396 | 13.1 | 3.0 | 2.76 | 2.75 |
| Chris Sale* | LAA | sp | 35 | .594 | 347 | .303 | 216 | .359 | 225 | .374 | 49.6 | 2.9 | 2.65 | 2.36 |
| Cristopher Sanchez* | Tam | sp | 27 | .660 | 575 | .299 | 314 | .392 | 323 | .403 | 77.9 | 3.5 | 3.19 | 3.07 |
| Nick Sandlin | Atl | mr | 27 | .713 | 218 | .275 | 152 | .446 | 157 | .460 | 38.8 | 4.3 | 3.94 | 3.75 |
| Patrick Sandoval* | | sp | 27 | .758 | 127 | .386 | 85 | .434 | 89 | .454 | 27.2 | 5.7 | 5.25 | 4.99 |
| Cole Sands | | mr | 26 | .638 | 213 | .291 | 121 | .389 | 123 | .395 | 30.7 | 3.6 | 3.33 | 2.83 |
| Tony Santillan | Col | mr | 27 | .855 | 144 | .340 | 120 | .517 | 125 | .539 | 36.7 | 6.8 | 6.10 | 6.56 |
| Gregory Santos | LAA | mr | 24 | .560 | 45 | .267 | 24 | .338 | 25 | .352 | 5.7 | 2.9 | 2.63 | 2.21 |
| Tayler Saucedo* | Mil | mr | 31 | .743 | 64 | .281 | 47 | .456 | 50 | .485 | 10.8 | 3.7 | 3.35 | 3.80 |
| Josh Sborz | SD | mr | 30 | .488 | 41 | .244 | 25 | .321 | 25 | .321 | 4.8 | 2.2 | 1.97 | 1.69 |
| Max Scherzer | | sp | 39 | .694 | 113 | .283 | 69 | .434 | 69 | .434 | 17.3 | 3.9 | 3.62 | 3.46 |
| Clarke Schmidt | Col | sp | 28 | .741 | 302 | .301 | 214 | .452 | 223 | .471 | 60.3 | 5.0 | 4.56 | 4.46 |
| John Schreiber | ChA | mr | 30 | .721 | 175 | .263 | 120 | .456 | 123 | .468 | 31.0 | 4.4 | 4.07 | 3.76 |
| Christian Scott | | sp | 25 | .689 | 375 | .296 | 209 | .399 | 223 | .426 | 59.6 | 4.3 | 3.86 | 3.50 |
| Tanner Scott* | NYN | mr | 29 | .656 | 147 | .293 | 113 | .415 | 116 | .426 | 25.1 | 3.4 | 3.01 | 2.98 |
| Tayler Scott | Phi | mr | 32 | .803 | 107 | .336 | 86 | .489 | 90 | .511 | 25.4 | 5.9 | 5.22 | 5.22 |
| JP Sears* | Cin | sp | 28 | .706 | 262 | .256 | 156 | .424 | 165 | .448 | 41.4 | 4.3 | 3.93 | 4.04 |
| Luis Severino | Tex | sp | 30 | .816 | 523 | .323 | 402 | .508 | 411 | .519 | 119.9 | 6.0 | 5.47 | 5.24 |
| Paul Sewald | LAA | cl | 34 | .719 | 126 | .270 | 90 | .443 | 94 | .463 | 22.8 | 4.2 | 3.80 | 3.76 |
| Ian Seymour* | Mia | sp | 25 | .657 | 55 | .309 | 33 | .398 | 34 | .410 | 8.3 | 3.6 | 3.31 | 2.70 |
| Davis Sharpe | Atl | mr | 24 | .688 | 339 | .310 | 206 | .406 | 215 | .423 | 56.1 | 4.1 | 3.65 | 3.48 |
| Chase Silseth | Sea | sp | 24 | .594 | 124 | .242 | 79 | .380 | 81 | .389 | 17.1 | 3.0 | 2.70 | 2.56 |
| Lucas Sims | Col | mr | 30 | .869 | 108 | .352 | 117 | .544 | 122 | .567 | 36.7 | 7.4 | 6.65 | 7.04 |
| Brady Singer | LAN | sp | 27 | .697 | 617 | .300 | 392 | .425 | 405 | .439 | 100.2 | 4.0 | 3.63 | 3.46 |
| Tarik Skubal* | Tam | sp | 27 | .746 | 617 | .323 | 410 | .456 | 418 | .465 | 113.1 | 4.7 | 4.27 | 3.90 |
| Cade Smith | Tam | mr | 25 | .642 | 171 | .263 | 109 | .378 | 119 | .413 | 28.1 | 3.7 | 3.46 | 3.51 |
| Drew Smith | NYN | mr | 30 | .575 | 54 | .296 | 30 | .341 | 32 | .364 | 7.4 | 3.1 | 2.81 | 2.12 |
| Will Smith* | ChN | cl | 34 | .757 | 155 | .258 | 130 | .498 | 130 | .498 | 34.2 | 5.0 | 4.47 | 4.25 |
| AJ Smith-Shawver | Tex | sp | 21 | .773 | 148 | .291 | 124 | .500 | 125 | .504 | 34.0 | 5.5 | 4.83 | 4.70 |
| Blake Snell* | Cin | sp | 31 | .690 | 361 | .294 | 295 | .449 | 296 | .451 | 72.1 | 4.2 | 3.78 | 3.67 |
| Robby Snelling* | Bal | sp | 20 | .694 | 603 | .262 | 378 | .440 | 381 | .444 | 94.9 | 4.2 | 3.75 | 3.57 |
| Collin Snider | Bos | mr | 28 | 1.070 | 35 | .400 | 37 | .698 | 37 | .698 | 11.7 | 9.1 | 8.15 | 8.17 |
| Jose Soriano | | mr | 25 | .761 | 271 | .269 | 236 | .480 | 250 | .508 | 61.9 | 4.8 | 4.36 | 4.53 |
| Mike Soroka | Ari | sp | 26 | .644 | 45 | .356 | 20 | .345 | 21 | .362 | 5.4 | 3.4 | 2.97 | 2.76 |
| Gregory Soto* | Cle | mr | 29 | .634 | 109 | .284 | 81 | .397 | 84 | .412 | 18.0 | 3.2 | 2.90 | 2.74 |
| Gabe Speier* | Was | mr | 29 | .675 | 84 | .333 | 45 | .378 | 48 | .403 | 11.6 | 3.6 | 3.23 | 3.18 |
| Mitch Spence | SF | sp | 26 | .666 | 312 | .295 | 178 | .402 | 183 | .413 | 44.8 | 3.7 | 3.35 | 3.10 |
| Carson Spiers | Cle | sp | 26 | .490 | 18 | .278 | 6 | .240 | 7 | .280 | 1.0 | 1.3 | 1.16 | 1.42 |
| Jeffrey Springs* | Bos | sp | 31 | .545 | 139 | .201 | 79 | .359 | 80 | .364 | 13.6 | 2.0 | 1.89 | 1.63 |
| Garrett Stallings | LAA | sp | 26 | .790 | 194 | .299 | 137 | .489 | 140 | .500 | 40.7 | 5.7 | 5.34 | 5.42 |
| Ryne Stanek | | mr | 32 | .585 | 108 | .296 | 60 | .357 | 61 | .363 | 11.7 | 2.4 | 2.21 | 2.13 |
| Cody Stashak | Cle | mr | 30 | .774 | 113 | .345 | 88 | .486 | 88 | .486 | 24.8 | 5.3 | 4.90 | 4.64 |
| Josh Staumont | Phi | mr | 30 | .431 | 23 | .217 | 10 | .250 | 11 | .275 | 2.1 | 1.9 | 1.81 | 1.81 |
| Justin Steele* | Tex | sp | 28 | .600 | 476 | .261 | 257 | .365 | 265 | .376 | 60.2 | 3.1 | 2.81 | 2.52 |
| Brock Stewart | Tex | mr | 32 | .684 | 40 | .225 | 37 | .457 | 38 | .469 | 8.5 | 3.8 | 3.49 | 3.32 |
| Gavin Stone | | sp | 25 | .735 | 323 | .297 | 211 | .460 | 211 | .460 | 55.2 | 4.5 | 4.02 | 3.64 |
| Matt Strahm* | Tor | mr | 32 | .689 | 305 | .289 | 208 | .434 | 211 | .441 | 51.9 | 4.0 | 3.68 | 3.49 |
| Hunter Stratton | | mr | 27 | .722 | 87 | .322 | 65 | .451 | 66 | .458 | 16.7 | 4.5 | 4.06 | 4.19 |
| Spencer Strider | Sea | sp | 25 | .485 | 20 | .250 | 16 | .333 | 16 | .333 | 3.1 | 2.2 | 2.01 | 1.50 |
| Marcus Stroman | Tam | sp | 33 | .693 | 633 | .302 | 368 | .423 | 371 | .426 | 97.9 | 4.2 | 3.81 | 3.45 |
| Peter Strzelecki | KC | mr | 29 | .662 | 245 | .286 | 158 | .407 | 163 | .420 | 40.9 | 3.9 | 3.58 | 3.31 |
| Jose Suarez* | | sp | 26 | .675 | 152 | .289 | 102 | .423 | 104 | .432 | 25.0 | 3.8 | 3.48 | 3.21 |
| Ranger Suarez* | ChN | sp | 28 | .702 | 540 | .289 | 348 | .438 | 352 | .443 | 81.2 | 3.8 | 3.41 | 3.56 |
| Robert Suarez | Tam | mr | 33 | .694 | 135 | .185 | 117 | .470 | 119 | .478 | 26.9 | 4.2 | 3.78 | 4.08 |
| Brent Suter* | LAN | mr | 34 | .637 | 128 | .258 | 78 | .406 | 78 | .406 | 18.1 | 3.4 | 3.09 | 2.66 |
| Erik Swanson | SD | mr | 30 | .686 | 131 | .366 | 80 | .402 | 81 | .407 | 22.8 | 4.4 | 4.04 | 3.77 |
| Devin Sweet | Oak | mr | 27 | .693 | 126 | .302 | 85 | .431 | 87 | .442 | 22.2 | 4.3 | 3.86 | 3.51 |
| Jameson Taillon | Tam | sp | 32 | .639 | 493 | .282 | 278 | .393 | 282 | .398 | 65.8 | 3.4 | 3.02 | 2.72 |
| Dillon Tate | StL | mr | 30 | .641 | 62 | .210 | 35 | .393 | 38 | .427 | 8.0 | 3.3 | 3.18 | 3.25 |
| Dylan Tebrake | SD | mr | 24 | .545 | 147 | .204 | 86 | .363 | 86 | .363 | 16.5 | 2.4 | 2.25 | 1.93 |
| Caleb Thielbar* | Pit | mr | 37 | .636 | 148 | .243 | 99 | .412 | 100 | .417 | 21.8 | 3.2 | 2.94 | 2.52 |
| Ryan Thompson | Bos | mr | 32 | .751 | 185 | .259 | 128 | .476 | 132 | .491 | 32.0 | 4.4 | 4.01 | 4.07 |
| Zack Thompson* | SF | sp | 26 | .685 | 275 | .276 | 170 | .420 | 176 | .435 | 43.2 | 4.1 | 3.70 | 3.72 |
| Trent Thornton | Mil | mr | 30 | .876 | 89 | .315 | 73 | .545 | 75 | .560 | 21.8 | 6.5 | 5.76 | 5.61 |
| Ricky Tiedemann* | Tex | sp | 21 | .624 | 19 | .316 | 12 | .387 | 12 | .387 | 2.8 | 3.7 | 3.29 | 3.77 |
| Michael Tonkin | NYN | mr | 34 | .744 | 7 | .286 | 5 | .500 | 5 | .500 | 0.4 | 1.3 | 1.15 | 1.95 |
| Blake Treinen | Pit | mr | 36 | .769 | 39 | .359 | 26 | .464 | 26 | .464 | 8.1 | 6.0 | 5.59 | 5.35 |
| Edwin Uceta | Pit | mr | 26 | .757 | 70 | .300 | 41 | .446 | 43 | .467 | 11.8 | 5.0 | 4.62 | 4.83 |
| Abner Uribe | Sea | mr | 24 | .622 | 33 | .364 | 26 | .382 | 26 | .382 | 6.1 | 3.5 | 3.05 | 3.36 |
| Framber Valdez* | LAA | sp | 30 | .609 | 496 | .280 | 270 | .358 | 286 | .379 | 60.7 | 2.9 | 2.60 | 2.66 |
| Reid VanScoter* | KC | sp | 25 | .763 | 626 | .318 | 381 | .458 | 390 | .469 | 110.3 | 5.0 | 4.57 | 4.24 |
| Louie Varland | Atl | sp | 26 | .784 | 466 | .328 | 326 | .481 | 332 | .490 | 94.8 | 5.5 | 4.96 | 4.70 |
| Mike Vasil | Ari | sp | 24 | .735 | 382 | .283 | 272 | .470 | 274 | .473 | 69.6 | 4.5 | 4.06 | 3.86 |
| Randy Vasquez | Det | sp | 25 | .815 | 30 | .233 | 29 | .537 | 30 | .556 | 8.4 | 6.1 | 5.36 | 5.13 |
| Justin Verlander | SD | sp | 41 | .642 | 322 | .267 | 177 | .393 | 180 | .400 | 40.5 | 3.3 | 2.93 | 2.87 |
| Alex Vesia* | Atl | mr | 28 | .539 | 140 | .221 | 90 | .354 | 91 | .358 | 17.8 | 2.6 | 2.34 | 2.24 |
| Nick Vespi* | Det | mr | 28 | .701 | 180 | .250 | 110 | .449 | 110 | .449 | 24.6 | 3.5 | 3.16 | 3.11 |
| Will Vest | | mr | 29 | .856 | 99 | .364 | 79 | .513 | 82 | .532 | 25.1 | 6.7 | 6.16 | 6.50 |
| Thyago Vieira | Mia | mr | 30 | .347 | 5 | .200 | 2 | .222 | 2 | .222 | 0.3 | 1.1 | 0.97 | 1.08 |
| Darius Vines | Tor | sp | 26 | .470 | 34 | .206 | 13 | .277 | 14 | .298 | 2.5 | 1.9 | 1.71 | 1.53 |
| Victor Vodnik | NYA | mr | 24 | .679 | 135 | .252 | 88 | .429 | 89 | .434 | 21.8 | 4.1 | 3.67 | 3.70 |
| Austin Voth | NYN | mr | 32 | .662 | 463 | .268 | 278 | .409 | 285 | .419 | 66.7 | 3.6 | 3.25 | 3.23 |
| Michael Wacha | | sp | 32 | .700 | 237 | .283 | 149 | .432 | 152 | .441 | 37.9 | 4.0 | 3.65 | 3.63 |
| Hurston Waldrep | Atl | sp | 22 | .689 | 145 | .324 | 98 | .428 | 98 | .428 | 26.5 | 4.5 | 4.12 | 3.97 |
| Matt Waldron | | sp | 27 | .721 | 551 | .270 | 354 | .451 | 363 | .462 | 93.5 | 4.5 | 4.05 | 3.80 |
| Ryan Walker | | mr | 28 | .776 | 133 | .383 | 109 | .480 | 110 | .485 | 30.4 | 5.2 | 4.65 | 4.67 |
| Taijuan Walker | | sp | 31 | .703 | 144 | .299 | 90 | .423 | 93 | .437 | 23.1 | 4.0 | 3.72 | 3.98 |
| Blake Walston* | ChN | sp | 23 | .563 | 270 | .233 | 141 | .342 | 148 | .359 | 33.0 | 2.9 | 2.66 | 2.46 |
| Will Warren | ChN | sp | 25 | .743 | 170 | .259 | 116 | .470 | 118 | .478 | 30.0 | 4.8 | 4.37 | 4.30 |
| Ryan Weathers* | Col | sp | 24 | .829 | 75 | .360 | 51 | .495 | 52 | .505 | 14.8 | 5.8 | 5.22 | 5.35 |
| Luke Weaver | Tam | sp | 30 | .825 | 119 | .328 | 89 | .509 | 90 | .514 | 28.0 | 6.6 | 5.97 | 5.79 |
| Jacob Webb | Mil | mr | 30 | .782 | 135 | .341 | 110 | .495 | 111 | .500 | 30.2 | 5.1 | 4.65 | 4.32 |
| Logan Webb | Oak | sp | 27 | .599 | 682 | .258 | 327 | .360 | 335 | .369 | 75.7 | 2.9 | 2.68 | 2.32 |
| Tyler Wells | StL | sp | 29 | .623 | 32 | .219 | 19 | .388 | 20 | .408 | 4.3 | 3.3 | 2.93 | 2.95 |
| Joey Wentz* | | sp | 26 | .653 | 49 | .245 | 31 | .419 | 32 | .432 | 7.1 | 3.4 | 3.13 | 2.61 |
| Hayden Wesneski | Col | sp | 26 | .704 | 232 | .259 | 158 | .457 | 159 | .460 | 38.9 | 4.2 | 3.79 | 3.50 |
| Zack Wheeler | | sp | 34 | .620 | 668 | .290 | 365 | .369 | 377 | .382 | 87.5 | 3.2 | 2.92 | 2.68 |
| Carson Whisenhunt* | KC | sp | 23 | .548 | 29 | .276 | 19 | .358 | 19 | .358 | 3.6 | 2.6 | 2.41 | 2.26 |
| Brendan White | Was | mr | 25 | .717 | 96 | .323 | 57 | .416 | 59 | .431 | 16.6 | 4.8 | 4.33 | 4.38 |
| Garrett Whitlock | Oak | mr | 28 | .697 | 60 | .300 | 41 | .436 | 41 | .436 | 11.0 | 4.6 | 4.12 | 3.79 |
| Jordan Wicks* | Tam | sp | 24 | .573 | 72 | .236 | 35 | .354 | 36 | .364 | 7.8 | 2.7 | 2.50 | 1.78 |
| Brad Wieck* | Cle | mr | 32 | .877 | 42 | .452 | 49 | .557 | 49 | .557 | 15.1 | 7.6 | 6.81 | 6.64 |
| Devin Williams | | cl | 29 | .754 | 51 | .333 | 46 | .479 | 47 | .490 | 12.6 | 5.3 | 4.85 | 4.59 |
| Gavin Williams | Ari | sp | 24 | .548 | 74 | .297 | 32 | .305 | 33 | .314 | 7.6 | 2.7 | 2.48 | 2.63 |
| Brandon Williamson* | Col | sp | 26 | .815 | 43 | .372 | 31 | .477 | 32 | .492 | 8.9 | 5.7 | 5.27 | 6.83 |
| Bryse Wilson | Tor | mr | 26 | .767 | 285 | .305 | 176 | .472 | 178 | .477 | 46.5 | 4.7 | 4.20 | 4.10 |
| Steven Wilson | Det | mr | 29 | .796 | 71 | .324 | 53 | .477 | 55 | .495 | 15.4 | 5.7 | 5.20 | 6.11 |
| Allan Winans | SD | sp | 28 | .621 | 398 | .274 | 210 | .371 | 217 | .383 | 48.9 | 3.1 | 2.81 | 2.57 |
| Josh Winckowski | KC | mr | 26 | .677 | 369 | .279 | 228 | .419 | 232 | .426 | 56.2 | 3.8 | 3.46 | 3.48 |
| Josh Winder | Mia | mr | 27 | .486 | 8 | .125 | 5 | .357 | 5 | .357 | 0.9 | 2.5 | 2.29 | 1.62 |
| Keaton Winn | SF | sp | 26 | .748 | 199 | .357 | 129 | .440 | 133 | .454 | 39.0 | 5.1 | 4.69 | 4.31 |
| Bryan Woo | Bos | sp | 24 | .621 | 336 | .274 | 197 | .383 | 202 | .392 | 44.6 | 3.1 | 2.79 | 2.66 |
| Alex Wood* | ChN | sp | 33 | .556 | 156 | .295 | 66 | .283 | 77 | .330 | 15.8 | 2.4 | 2.15 | 2.26 |
| Simeon Woods Richardso | | sp | 23 | .647 | 66 | .303 | 40 | .396 | 40 | .396 | 10.1 | 3.8 | 3.51 | 3.72 |
| Yoshinobu Yamamoto | Col | sp | 25 | .642 | 288 | .274 | 162 | .394 | 164 | .399 | 39.1 | 3.5 | 3.19 | 2.98 |
| Kirby Yates | StL | mr | 37 | .644 | 26 | .308 | 22 | .400 | 24 | .436 | 5.1 | 3.9 | 3.57 | 4.22 |
| Huascar Ynoa | Mil | sp | 26 | .396 | 17 | .176 | 5 | .185 | 7 | .259 | 1.2 | 1.5 | 1.43 | 1.13 |
| Brandon Young | Hou | sp | 25 | .719 | 76 | .329 | 44 | .423 | 45 | .433 | 12.5 | 4.6 | 4.10 | 4.09 |
| Ryan Zeferjahn | Bos | mr | 26 | .905 | 19 | .211 | 13 | .520 | 15 | .600 | 3.7 | 5.6 | 5.03 | 6.60 |
| Angel Zerpa* | Bal | sp | 24 | .811 | 177 | .305 | 118 | .490 | 121 | .502 | 34.8 | 5.7 | 5.13 | 4.93 |
| Yosver Zulueta | Col | mr | 26 | 1.067 | 144 | .382 | 153 | .637 | 161 | .671 | 58.2 | 11.4 | 10.48 | 10.76 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | PCH/G | STR% |
| Andrew Abbott* | | sp | 25 | 27 | 0 | .000 | 0 | 13 | .481 | 147 | 5.4 | 18 | 5 | .278 | 95.0 | .619 |
| Mick Abel | Sea | sp | 22 | 6 | 0 | .000 | 0 | 3 | .500 | 24 | 4.0 | 4 | 0 | .000 | 92.2 | .642 |
| Bryan Abreu | Sea | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 9 | .474 | 20.2 | .617 |
| Jason Adam | Ari | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 20.0 | .635 |
| Austin L. Adams | Hou | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 16.6 | .528 |
| Ty Adcock | Det | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 15.8 | .682 |
| Keegan Akin* | LAA | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 2 | .133 | 18.6 | .649 |
| Jorge Alcala | Bal | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 19.3 | .620 |
| Franco Aleman | Col | mr | 24 | 2 | 0 | .000 | 0 | 1 | .500 | 14 | 7.0 | 19 | 1 | .053 | 27.3 | .627 |
| Scott Alexander* | | mr | 34 | 3 | 0 | .000 | 0 | 1 | .333 | 18 | 6.0 | 4 | 2 | .500 | 36.8 | .619 |
| Tyler Alexander* | ChA | mr | 29 | 31 | 1 | .032 | 0 | 17 | .548 | 127 | 4.1 | 14 | 8 | .571 | 89.8 | .687 |
| Logan T. Allen* | Was | sp | 25 | 24 | 0 | .000 | 0 | 15 | .625 | 103 | 4.3 | 13 | 4 | .308 | 88.6 | .630 |
| Jose Alvarado* | Ari | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 6 | .750 | 18.0 | .631 |
| Adbert Alzolay | ChN | cl | 29 | 10 | 0 | .000 | 0 | 4 | .400 | 48 | 4.8 | 3 | 0 | .000 | 88.9 | .665 |
| Ian Anderson | Atl | sp | 26 | 13 | 0 | .000 | 0 | 7 | .538 | 53 | 4.1 | 10 | 4 | .400 | 103.2 | .600 |
| Nick Anderson | Was | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 21.5 | .658 |
| Tyler Anderson* | | sp | 34 | 28 | 3 | .107 | 2 | 13 | .464 | 155 | 5.5 | 6 | 3 | .500 | 98.4 | .656 |
| Luarbert Arias | Col | mr | 23 | 2 | 0 | .000 | 0 | 0 | .000 | 5 | 2.5 | 39 | 21 | .538 | 24.5 | .632 |
| Shawn Armstrong | Ari | mr | 33 | 32 | 0 | .000 | 0 | 14 | .438 | 189 | 5.9 | 11 | 1 | .091 | 82.4 | .647 |
| Spencer Arrighetti | | sp | 24 | 27 | 0 | .000 | 0 | 11 | .407 | 111 | 4.1 | 24 | 12 | .500 | 70.8 | .611 |
| Aaron Ashby* | SD | sp | 26 | 1 | 0 | .000 | 0 | 1 | 1.000 | 4 | 4.0 | 4 | 1 | .250 | 21.9 | .610 |
| Braxton Ashcraft | Atl | sp | 24 | 20 | 0 | .000 | 0 | 6 | .300 | 95 | 4.8 | 12 | 6 | .500 | 82.5 | .659 |
| Graham Ashcraft | Was | sp | 26 | 22 | 4 | .182 | 1 | 15 | .682 | 89 | 4.0 | 12 | 3 | .250 | 101.8 | .636 |
| Pedro Avila | | sp | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 9 | 9.0 | 3 | 1 | .333 | 26.0 | .643 |
| Anthony Banda* | Mia | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 28.0 | .655 |
| Tanner Banks* | Tam | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 4 | .308 | 21.7 | .663 |
| Scott Barlow | ChN | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 23.5 | .629 |
| Jaime Barria | ChN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 27.0 | .677 |
| Chris Bassitt | Mil | sp | 35 | 33 | 6 | .182 | 1 | 26 | .788 | 165 | 5.0 | 11 | 1 | .091 | 104.0 | .660 |
| Brady Basso* | Min | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 5 | .238 | 14.2 | .665 |
| Mike Baumann | Bal | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 21.7 | .575 |
| Jarod Bayless | Phi | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 23.0 | .614 |
| Shane Baz | Bal | sp | 25 | 29 | 0 | .000 | 0 | 9 | .310 | 125 | 4.3 | 17 | 5 | .294 | 71.5 | .618 |
| Eduard Bazardo | Pit | mr | 28 | 6 | 0 | .000 | 0 | 2 | .333 | 24 | 4.0 | 8 | 1 | .125 | 60.9 | .641 |
| David Bednar | Tam | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 20.1 | .620 |
| Jalen Beeks* | LAN | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 10 | .455 | 30.3 | .625 |
| Clayton Beeter | NYA | sp | 25 | 10 | 0 | .000 | 0 | 3 | .300 | 45 | 4.5 | 17 | 3 | .176 | 46.7 | .600 |
| Brayan Bello | Mil | sp | 25 | 31 | 1 | .032 | 1 | 16 | .516 | 127 | 4.1 | 18 | 8 | .444 | 95.5 | .635 |
| Anthony Bender | Mil | mr | 29 | 26 | 0 | .000 | 0 | 20 | .769 | 98 | 3.8 | 24 | 9 | .375 | 79.1 | .647 |
| Brennan Bernardino* | NYA | mr | 32 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 8 | 0 | .000 | 17.7 | .610 |
| Jose Berrios | Tor | sp | 30 | 31 | 4 | .129 | 1 | 16 | .516 | 148 | 4.8 | 11 | 5 | .455 | 99.8 | .661 |
| Prelander Berroa | SF | mr | 24 | 9 | 0 | .000 | 0 | 0 | .000 | 33 | 3.7 | 69 | 28 | .406 | 24.6 | .524 |
| Tanner Bibee | Was | sp | 25 | 24 | 0 | .000 | 0 | 11 | .458 | 106 | 4.4 | 13 | 2 | .154 | 100.9 | .638 |
| Phil Bickford | Mil | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 | 16.5 | .604 |
| Osvaldo Bido | Mia | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 2 | .667 | 25.5 | .601 |
| Shane Bieber | Tor | sp | 29 | 2 | 1 | .500 | 0 | 2 | 1.000 | 12 | 6.0 | 0 | 0 | .000 | 95.5 | .702 |
| Hunter Bigge | Sea | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 24.4 | .598 |
| Hayden Birdsong | Bos | sp | 22 | 10 | 0 | .000 | 0 | 4 | .400 | 51 | 5.1 | 18 | 8 | .444 | 38.0 | .589 |
| Mason Black | Min | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 45.5 | .648 |
| Ronel Blanco | Col | mr | 30 | 17 | 0 | .000 | 0 | 9 | .529 | 83 | 4.9 | 13 | 6 | .462 | 49.3 | .616 |
| Jonathan Bowlan | SF | sp | 27 | 8 | 0 | .000 | 0 | 1 | .125 | 38 | 4.8 | 29 | 6 | .207 | 28.6 | .616 |
| Joe Boyle | NYA | sp | 24 | 11 | 0 | .000 | 0 | 4 | .364 | 35 | 3.2 | 9 | 5 | .556 | 48.5 | .557 |
| Cody Bradford* | Tam | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 23.7 | .641 |
| Kyle Bradish | Bal | sp | 27 | 8 | 0 | .000 | 0 | 6 | .750 | 48 | 6.0 | 3 | 1 | .333 | 99.6 | .630 |
| Taj Bradley | | sp | 23 | 26 | 0 | .000 | 0 | 9 | .346 | 109 | 4.2 | 14 | 5 | .357 | 90.5 | .610 |
| Ryan Brasier | Pit | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 | 22.9 | .663 |
| Huascar Brazoban | NYN | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 23.3 | .629 |
| John Brebbia | ChA | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 8.5 | .765 |
| Beau Brieske | StL | mr | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 4 | 2.0 | 0 | 0 | .000 | 94.5 | .624 |
| Trevor Brigden | Cin | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 | 17.9 | .594 |
| Jhony Brito | ChA | sp | 26 | 17 | 0 | .000 | 0 | 10 | .588 | 62 | 3.6 | 30 | 9 | .300 | 35.0 | .649 |
| Kyle Brnovich | StL | sp | 26 | 20 | 0 | .000 | 0 | 10 | .500 | 101 | 5.1 | 11 | 5 | .455 | 74.7 | .643 |
| T.J. Brock | Phi | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 22.7 | .590 |
| Ben Brown | Sea | sp | 24 | 16 | 0 | .000 | 0 | 4 | .250 | 82 | 5.1 | 9 | 2 | .222 | 86.8 | .622 |
| Hunter Brown | Hou | sp | 25 | 34 | 0 | .000 | 0 | 20 | .588 | 174 | 5.1 | 27 | 9 | .333 | 99.0 | .620 |
| Zach Brzykcy | Phi | mr | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 16 | 16.0 | 32 | 7 | .219 | 25.8 | .582 |
| Kris Bubic* | Tex | sp | 26 | 5 | 0 | .000 | 0 | 3 | .600 | 20 | 4.0 | 11 | 3 | .273 | 36.5 | .620 |
| Walker Buehler | LAA | sp | 29 | 17 | 0 | .000 | 0 | 12 | .706 | 91 | 5.4 | 9 | 5 | .556 | 90.6 | .675 |
| Aaron Bummer* | Oak | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 4 | .250 | 16.7 | .616 |
| Brock Burke* | SD | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 0 | .000 | 20.0 | .661 |
| Sean Burke | LAA | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 17.7 | .540 |
| Corbin Burnes | Ari | sp | 29 | 36 | 5 | .139 | 1 | 23 | .639 | 165 | 4.6 | 16 | 5 | .313 | 112.7 | .638 |
| Mike Burrows | Tex | sp | 24 | 5 | 0 | .000 | 0 | 1 | .200 | 18 | 3.6 | 0 | 0 | .000 | 41.8 | .616 |
| Jose Butto | Sea | sp | 26 | 12 | 0 | .000 | 0 | 3 | .250 | 28 | 2.3 | 8 | 4 | .500 | 49.7 | .616 |
| Edward Cabrera | Atl | sp | 26 | 7 | 0 | .000 | 0 | 2 | .286 | 34 | 4.9 | 9 | 4 | .444 | 47.5 | .621 |
| Genesis Cabrera* | Tam | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 7 | .269 | 18.4 | .623 |
| Isaiah Campbell | Ari | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 18.0 | .660 |
| Griffin Canning | Cin | sp | 28 | 18 | 0 | .000 | 0 | 10 | .556 | 80 | 4.4 | 9 | 2 | .222 | 76.8 | .617 |
| Yennier Cano | ChN | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 | 17.1 | .658 |
| Joey Cantillo* | SF | sp | 24 | 13 | 0 | .000 | 0 | 7 | .538 | 44 | 3.4 | 72 | 24 | .333 | 32.3 | .573 |
| Luis Castillo | Bos | sp | 31 | 30 | 4 | .133 | 2 | 23 | .767 | 155 | 5.2 | 16 | 4 | .250 | 111.2 | .636 |
| Miguel Castro | Min | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 19.2 | .612 |
| Tim Cate* | LAN | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 16.4 | .591 |
| Dylan Cease | Mil | sp | 28 | 33 | 3 | .091 | 1 | 16 | .485 | 164 | 5.0 | 19 | 10 | .526 | 110.0 | .608 |
| Slade Cecconi | SD | sp | 25 | 31 | 1 | .032 | 0 | 25 | .806 | 113 | 3.6 | 10 | 1 | .100 | 98.5 | .672 |
| Andrew Chafin* | Oak | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 | 16.6 | .612 |
| Chandler Champlain | | sp | 24 | 12 | 0 | .000 | 0 | 4 | .333 | 70 | 5.8 | 16 | 8 | .500 | 66.9 | .629 |
| Aroldis Chapman* | LAA | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 8 | .364 | 17.1 | .581 |
| Jesse Chavez | ChA | mr | 40 | 5 | 0 | .000 | 0 | 0 | .000 | 11 | 2.2 | 34 | 9 | .265 | 19.6 | .622 |
| Aaron Civale | Min | sp | 29 | 26 | 0 | .000 | 0 | 14 | .538 | 123 | 4.7 | 11 | 2 | .182 | 96.0 | .646 |
| Emmanuel Clase | Sea | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 18.8 | .654 |
| Garrett Cleavinger* | Ari | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 5 | .227 | 19.7 | .611 |
| Alex Cobb | SD | sp | 36 | 5 | 0 | .000 | 0 | 3 | .600 | 11 | 2.2 | 3 | 1 | .333 | 92.4 | .680 |
| Isaac Coffey | Cin | sp | 24 | 24 | 1 | .042 | 0 | 15 | .625 | 122 | 5.1 | 8 | 1 | .125 | 95.2 | .640 |
| Gerrit Cole | Oak | sp | 33 | 17 | 2 | .118 | 1 | 9 | .529 | 77 | 4.5 | 9 | 2 | .222 | 102.3 | .641 |
| Luis Contreras | StL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 30.7 | .633 |
| Roansy Contreras | Det | sp | 24 | 35 | 1 | .029 | 0 | 17 | .486 | 154 | 4.4 | 21 | 4 | .190 | 87.9 | .639 |
| Connor Cooke | Pit | mr | 24 | 13 | 0 | .000 | 0 | 4 | .308 | 54 | 4.2 | 24 | 9 | .375 | 41.4 | .615 |
| Nestor Cortes* | | sp | 29 | 34 | 2 | .059 | 1 | 25 | .735 | 141 | 4.1 | 13 | 0 | .000 | 97.1 | .663 |
| Tom Cosgrove* | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 21.4 | .613 |
| Danny Coulombe* | Det | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 16.4 | .678 |
| Jake Cousins | Mil | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 27.3 | .541 |
| Austin Cox* | ChA | sp | 27 | 4 | 0 | .000 | 0 | 1 | .250 | 17 | 4.3 | 6 | 4 | .667 | 38.4 | .610 |
| Kutter Crawford | Det | sp | 28 | 21 | 0 | .000 | 0 | 11 | .524 | 71 | 3.4 | 10 | 1 | .100 | 84.3 | .649 |
| Garrett Crochet* | | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 8 | .381 | 19.4 | .612 |
| Declan Cronin | | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 17.2 | .635 |
| Hans Crouse | Sea | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.0 | .682 |
| Fernando Cruz | | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 19.9 | .624 |
| Hagen Danner | Cin | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 | 19.6 | .629 |
| Yu Darvish | | sp | 37 | 16 | 1 | .063 | 0 | 14 | .875 | 89 | 5.6 | 3 | 0 | .000 | 101.4 | .639 |
| Enyel De Los Santos | Mil | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 1 | .077 | 18.2 | .636 |
| Jacob deGrom | Cle | sp | 36 | 3 | 0 | .000 | 0 | 2 | .667 | 7 | 2.3 | 1 | 0 | .000 | 94.7 | .680 |
| Reid Detmers* | | sp | 24 | 32 | 0 | .000 | 0 | 18 | .563 | 167 | 5.2 | 11 | 2 | .182 | 94.0 | .638 |
| Chris Devenski | ChN | mr | 33 | 20 | 1 | .050 | 1 | 11 | .550 | 93 | 4.7 | 9 | 1 | .111 | 83.1 | .659 |
| Alexis Diaz | | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 11 | .407 | 19.6 | .600 |
| Edwin Diaz | | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 19.0 | .613 |
| Miguel Diaz | SD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 25.8 | .603 |
| Yilber Diaz | | sp | 23 | 9 | 0 | .000 | 0 | 1 | .111 | 39 | 4.3 | 9 | 5 | .556 | 74.7 | .607 |
| Jake Diekman* | SD | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.7 | .554 |
| Hunter Dobbins | Sea | sp | 24 | 9 | 0 | .000 | 0 | 4 | .444 | 24 | 2.7 | 4 | 2 | .500 | 84.3 | .669 |
| Seranthony Dominguez | Was | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 17 | .531 | 21.2 | .591 |
| Camilo Doval | Oak | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 20.2 | .610 |
| Shawn Dubin | Was | sp | 28 | 11 | 0 | .000 | 0 | 4 | .364 | 39 | 3.5 | 8 | 2 | .250 | 70.1 | .613 |
| Dane Dunning | LAA | sp | 29 | 19 | 0 | .000 | 0 | 9 | .474 | 100 | 5.3 | 21 | 6 | .286 | 53.9 | .639 |
| Jhoan Duran | Sea | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 2 | .125 | 20.4 | .655 |
| Jake Eder* | Tex | sp | 25 | 10 | 0 | .000 | 0 | 1 | .100 | 37 | 3.7 | 8 | 0 | .000 | 64.4 | .583 |
| Scott Effross | Det | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 19.9 | .636 |
| Zach Eflin | | sp | 30 | 27 | 1 | .037 | 1 | 12 | .444 | 118 | 4.4 | 13 | 4 | .308 | 92.9 | .684 |
| Brandon Eisert* | Det | mr | 26 | 11 | 0 | .000 | 0 | 6 | .545 | 33 | 3.0 | 5 | 1 | .200 | 57.7 | .636 |
| Bryce Elder | | sp | 25 | 33 | 3 | .091 | 0 | 18 | .545 | 127 | 3.8 | 10 | 4 | .400 | 96.6 | .622 |
| Fraser Ellard* | Sea | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 32.0 | .531 |
| Nic Enright | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 4 | .571 | 25.1 | .668 |
| Nathan Eovaldi | Oak | sp | 34 | 22 | 0 | .000 | 0 | 14 | .636 | 64 | 2.9 | 5 | 0 | .000 | 96.3 | .640 |
| Lucas Erceg | LAN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 20.7 | .537 |
| Joey Estes | Mia | sp | 22 | 4 | 0 | .000 | 0 | 1 | .250 | 33 | 8.3 | 5 | 1 | .200 | 47.2 | .624 |
| Carlos Estevez | Tor | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 7 | .318 | 19.4 | .597 |
| Jeremiah Estrada | Sea | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 9 | .321 | 25.1 | .586 |
| Alex Faedo | Phi | sp | 28 | 23 | 1 | .043 | 0 | 11 | .478 | 100 | 4.3 | 19 | 7 | .368 | 78.4 | .633 |
| Pete Fairbanks | ChN | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 1 | .067 | 19.0 | .592 |
| Bailey Falter* | KC | sp | 27 | 9 | 0 | .000 | 0 | 3 | .333 | 26 | 2.9 | 4 | 2 | .500 | 90.2 | .658 |
| Calvin Faucher | Hou | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 20.3 | .578 |
| Erick Fedde | Hou | sp | 31 | 5 | 0 | .000 | 0 | 1 | .200 | 36 | 7.2 | 5 | 0 | .000 | 45.9 | .654 |
| Caleb Ferguson* | Tor | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 4 | .250 | 18.4 | .630 |
| Ryan Fernandez | SD | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 7 | .700 | 23.2 | .631 |
| Jose A. Ferrer* | Mia | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 24.6 | .605 |
| David Festa | | sp | 24 | 20 | 0 | .000 | 0 | 6 | .300 | 86 | 4.3 | 38 | 16 | .421 | 54.0 | .611 |
| J.P. Feyereisen | Pit | mr | 31 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 11 | 0 | .000 | 21.4 | .620 |
| Kyle Finnegan | NYN | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 21.3 | .645 |
| Richard Fitts | | sp | 24 | 20 | 2 | .100 | 1 | 10 | .500 | 87 | 4.3 | 5 | 0 | .000 | 96.4 | .659 |
| Jack Flaherty | Hou | sp | 28 | 33 | 1 | .030 | 1 | 20 | .606 | 140 | 4.2 | 14 | 6 | .429 | 98.8 | .608 |
| Josh Fleming* | Tam | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 16.3 | .684 |
| Wilmer Flores | ChN | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 77.0 | .649 |
| Dylan Floro | Was | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 20.8 | .685 |
| Mason Fluharty* | Phi | mr | 22 | 2 | 0 | .000 | 0 | 0 | .000 | 4 | 2.0 | 35 | 13 | .371 | 26.1 | .626 |
| Jason Foley | Oak | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 19.7 | .661 |
| J.P. France | KC | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 7 | .389 | 21.7 | .631 |
| Bowden Francis | Tex | sp | 28 | 7 | 0 | .000 | 0 | 3 | .429 | 31 | 4.4 | 1 | 0 | .000 | 72.6 | .640 |
| Kyle Freeland* | Min | sp | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 21.0 | .714 |
| Luis Frias | Bal | mr | 26 | 20 | 0 | .000 | 0 | 4 | .200 | 84 | 4.2 | 20 | 5 | .250 | 85.7 | .602 |
| Max Fried* | Ari | sp | 30 | 32 | 2 | .063 | 1 | 25 | .781 | 159 | 5.0 | 12 | 2 | .167 | 99.6 | .663 |
| Kody Funderburk* | ChN | mr | 27 | 11 | 0 | .000 | 0 | 3 | .273 | 47 | 4.3 | 2 | 0 | .000 | 94.3 | .608 |
| Hunter Gaddis | Bos | sp | 26 | 24 | 0 | .000 | 0 | 11 | .458 | 126 | 5.3 | 23 | 10 | .435 | 63.6 | .616 |
| Giovanny Gallegos | | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 | 18.7 | .645 |
| Zac Gallen | | sp | 28 | 29 | 6 | .207 | 3 | 22 | .759 | 147 | 5.1 | 18 | 6 | .333 | 106.8 | .647 |
| Robert Garcia* | Was | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 32.5 | .602 |
| Yimi Garcia | | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 3 | .158 | 19.4 | .627 |
| Braxton Garrett* | Mia | sp | 26 | 9 | 0 | .000 | 0 | 7 | .778 | 35 | 3.9 | 1 | 0 | .000 | 92.6 | .660 |
| Reed Garrett | NYN | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 24.9 | .638 |
| Robert Gasser* | Atl | sp | 25 | 7 | 0 | .000 | 0 | 3 | .429 | 27 | 3.9 | 6 | 4 | .667 | 88.1 | .637 |
| Chris Gau | Oak | mr | 27 | 15 | 0 | .000 | 0 | 8 | .533 | 64 | 4.3 | 10 | 2 | .200 | 72.1 | .629 |
| Kevin Gausman | | sp | 33 | 37 | 1 | .027 | 0 | 21 | .568 | 146 | 3.9 | 15 | 1 | .067 | 101.3 | .659 |
| Domingo German | Pit | sp | 31 | 33 | 1 | .030 | 0 | 21 | .636 | 131 | 4.0 | 16 | 7 | .438 | 98.6 | .652 |
| Kyle Gibson | Min | sp | 36 | 29 | 1 | .034 | 0 | 16 | .552 | 144 | 5.0 | 11 | 6 | .545 | 100.8 | .618 |
| Luis Gil | | sp | 26 | 24 | 0 | .000 | 0 | 6 | .250 | 85 | 3.5 | 12 | 3 | .250 | 75.9 | .588 |
| Logan Gilbert | Ari | sp | 27 | 34 | 4 | .118 | 2 | 21 | .618 | 154 | 4.5 | 14 | 2 | .143 | 110.7 | .644 |
| Keagan Gillies | Cin | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 34.5 | .667 |
| Kevin Ginkel | | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 23.4 | .604 |
| J.T. Ginn | Pit | sp | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 8 | 2.7 | 2 | 1 | .500 | 88.0 | .614 |
| Tyler Glasnow | Sea | sp | 30 | 23 | 0 | .000 | 0 | 11 | .478 | 79 | 3.4 | 16 | 5 | .313 | 86.1 | .652 |
| Woo-suk Go | Mil | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 19.7 | .606 |
| Yoendrys Gomez | NYA | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 6 | .462 | 15.3 | .595 |
| Marco Gonzales* | ChA | sp | 32 | 2 | 0 | .000 | 0 | 0 | .000 | 13 | 6.5 | 0 | 0 | .000 | 106.5 | .638 |
| Colton Gordon* | Phi | sp | 25 | 3 | 0 | .000 | 0 | 0 | .000 | 16 | 5.3 | 12 | 3 | .250 | 23.2 | .615 |
| MacKenzie Gore* | NYN | sp | 25 | 33 | 2 | .061 | 2 | 22 | .667 | 134 | 4.1 | 22 | 8 | .364 | 101.3 | .621 |
| Anthony Gose* | Hou | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 7 | .350 | 19.1 | .570 |
| Gordon Graceffo | | sp | 24 | 6 | 0 | .000 | 0 | 4 | .667 | 26 | 4.3 | 24 | 2 | .083 | 29.6 | .624 |
| Brusdar Graterol | Bal | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 16.9 | .708 |
| Jon Gray | Oak | sp | 32 | 27 | 1 | .037 | 1 | 16 | .593 | 128 | 4.7 | 16 | 5 | .313 | 94.1 | .645 |
| Sonny Gray | | sp | 34 | 26 | 2 | .077 | 1 | 14 | .538 | 107 | 4.1 | 17 | 7 | .412 | 96.9 | .640 |
| Chad Green | ChN | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 9 | .500 | 18.9 | .657 |
| Hunter Greene | Col | sp | 24 | 23 | 1 | .043 | 0 | 7 | .304 | 111 | 4.8 | 19 | 4 | .211 | 97.4 | .615 |
| Michael Grove | | sp | 27 | 5 | 0 | .000 | 0 | 2 | .400 | 29 | 5.8 | 7 | 1 | .143 | 26.1 | .642 |
| Luis Guerrero | Tor | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 | 24.3 | .599 |
| Tyson Guerrero* | Sea | sp | 25 | 1 | 0 | .000 | 0 | 1 | 1.000 | 4 | 4.0 | 0 | 0 | .000 | 78.0 | .692 |
| Josh Hader* | | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 4 | .222 | 14.3 | .648 |
| Justin Hagenman | Oak | mr | 27 | 14 | 0 | .000 | 0 | 7 | .500 | 74 | 5.3 | 8 | 2 | .250 | 82.1 | .618 |
| DL Hall* | Bal | mr | 25 | 20 | 0 | .000 | 0 | 2 | .100 | 92 | 4.6 | 22 | 5 | .227 | 45.9 | .601 |
| Ian Hamilton | Tex | mr | 29 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 15 | 2 | .133 | 25.3 | .615 |
| Emerson Hancock | Sea | sp | 25 | 31 | 1 | .032 | 1 | 17 | .548 | 104 | 3.4 | 14 | 6 | .429 | 91.5 | .638 |
| Hayden Harris* | | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 9 | .600 | 19.5 | .614 |
| Kyle Harrison* | Atl | sp | 22 | 27 | 0 | .000 | 0 | 3 | .111 | 101 | 3.7 | 23 | 2 | .087 | 85.7 | .595 |
| Grant Hartwig | NYN | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 17.9 | .556 |
| Hunter Harvey | | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 | 15.3 | .675 |
| Andrew Heaney* | KC | sp | 33 | 16 | 0 | .000 | 0 | 9 | .563 | 66 | 4.1 | 7 | 0 | .000 | 86.6 | .634 |
| Ryan Helsley | | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 17.8 | .625 |
| Markevian Hence | SF | sp | 21 | 17 | 0 | .000 | 0 | 5 | .294 | 76 | 4.5 | 21 | 6 | .286 | 39.8 | .632 |
| Ryan Hennen* | Det | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 | 22.9 | .658 |
| Ronny Henriquez | Was | mr | 24 | 6 | 1 | .167 | 0 | 3 | .500 | 25 | 4.2 | 8 | 1 | .125 | 59.7 | .633 |
| Cole Henry | Pit | sp | 24 | 18 | 0 | .000 | 0 | 5 | .278 | 93 | 5.2 | 9 | 3 | .333 | 64.6 | .613 |
| Tommy Henry* | LAA | sp | 26 | 6 | 0 | .000 | 0 | 3 | .500 | 25 | 4.2 | 13 | 11 | .846 | 31.5 | .622 |
| Sam Hentges* | Tex | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 18.1 | .633 |
| Carlos Hernandez | Tex | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 40.0 | .600 |
| Daysbel Hernandez | NYN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.0 | .568 |
| Jakob Hernandez* | Oak | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 16.7 | .560 |
| Jose Hernandez* | Was | mr | 26 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 5 | 1 | .200 | 22.5 | .592 |
| Tim Herrin* | Sea | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 26.4 | .606 |
| Jordan Hicks | SF | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 59 | 18 | .305 | 18.9 | .575 |
| Porter Hodge | Was | mr | 23 | 12 | 0 | .000 | 0 | 5 | .417 | 49 | 4.1 | 7 | 2 | .286 | 72.5 | .587 |
| Jeff Hoffman | | mr | 31 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 15 | 4 | .267 | 21.1 | .613 |
| Gunnar Hoglund | Oak | sp | 24 | 5 | 0 | .000 | 0 | 1 | .200 | 25 | 5.0 | 2 | 2 | 1.000 | 79.6 | .681 |
| Colin Holderman | Phi | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 7 | .389 | 19.6 | .616 |
| Grant Holman | KC | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 30 | 7 | .233 | 13.5 | .637 |
| Clay Holmes | Oak | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 5 | .156 | 19.1 | .637 |
| Grant Holmes | Mia | mr | 28 | 2 | 0 | .000 | 0 | 2 | 1.000 | 6 | 3.0 | 9 | 2 | .222 | 24.5 | .641 |
| Tyler Holton* | | mr | 28 | 3 | 0 | .000 | 0 | 2 | .667 | 16 | 5.3 | 13 | 6 | .462 | 20.8 | .666 |
| Brent Honeywell | Col | mr | 29 | 5 | 0 | .000 | 0 | 4 | .800 | 23 | 4.6 | 6 | 2 | .333 | 56.5 | .635 |
| Tanner Houck | LAN | sp | 28 | 33 | 0 | .000 | 0 | 15 | .455 | 153 | 4.6 | 21 | 9 | .429 | 94.2 | .612 |
| Spencer Howard | | sp | 27 | 2 | 0 | .000 | 0 | 0 | .000 | 8 | 4.0 | 9 | 2 | .222 | 27.2 | .608 |
| Bryan Hudson* | Col | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 6 | .240 | 19.9 | .616 |
| Daniel Hudson | | mr | 37 | 5 | 0 | .000 | 0 | 2 | .400 | 21 | 4.2 | 10 | 2 | .200 | 30.2 | .618 |
| Brandon Hughes* | NYN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 19.0 | .595 |
| Kyle Hurt | Bos | sp | 26 | 6 | 0 | .000 | 0 | 1 | .167 | 29 | 4.8 | 3 | 0 | .000 | 77.6 | .615 |
| Brant Hurter* | ChN | sp | 25 | 33 | 0 | .000 | 0 | 21 | .636 | 177 | 5.4 | 15 | 7 | .467 | 86.4 | .644 |
| Raisel Iglesias | | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 17.0 | .686 |
| Shota Imanaga* | SD | sp | 30 | 33 | 0 | .000 | 0 | 10 | .303 | 144 | 4.4 | 20 | 3 | .150 | 82.4 | .640 |
| Jairo Iriarte | Col | sp | 22 | 3 | 0 | .000 | 0 | 0 | .000 | 21 | 7.0 | 12 | 7 | .583 | 29.3 | .580 |
| Cole Irvin* | ChA | sp | 30 | 32 | 5 | .156 | 0 | 16 | .500 | 95 | 3.0 | 10 | 2 | .200 | 89.6 | .668 |
| Jake Irvin | | sp | 27 | 21 | 0 | .000 | 0 | 12 | .571 | 99 | 4.7 | 14 | 4 | .286 | 88.9 | .602 |
| Jay Jackson | Mia | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 0 | .000 | 18.2 | .637 |
| Alek Jacob | Pit | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 24.9 | .613 |
| Kenley Jansen | | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 4 | .222 | 19.1 | .604 |
| Bryce Jarvis | LAA | sp | 26 | 5 | 0 | .000 | 0 | 3 | .600 | 34 | 6.8 | 8 | 3 | .375 | 32.6 | .605 |
| Cristian Javier | Min | sp | 27 | 6 | 0 | .000 | 0 | 4 | .667 | 24 | 4.0 | 2 | 1 | .500 | 104.0 | .607 |
| Griffin Jax | Min | mr | 29 | 3 | 0 | .000 | 0 | 1 | .333 | 11 | 3.7 | 9 | 3 | .333 | 23.6 | .641 |
| Joe Jimenez | NYN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 | 17.7 | .617 |
| Jackson Jobe | SF | sp | 21 | 15 | 0 | .000 | 0 | 4 | .267 | 57 | 3.8 | 11 | 2 | .182 | 45.2 | .615 |
| Pierce Johnson | Mil | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 | 18.1 | .607 |
| Seth Johnson | Phi | sp | 25 | 14 | 0 | .000 | 0 | 5 | .357 | 51 | 3.6 | 14 | 6 | .429 | 55.8 | .611 |
| Jared Jones | Bos | sp | 22 | 22 | 0 | .000 | 0 | 10 | .455 | 89 | 4.0 | 9 | 4 | .444 | 101.0 | .606 |
| Hayden Juenger | Hou | mr | 23 | 6 | 0 | .000 | 0 | 3 | .500 | 21 | 3.5 | 19 | 8 | .421 | 32.3 | .593 |
| Jakob Junis | Det | mr | 31 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 4 | 3 | .750 | 36.3 | .670 |
| Tommy Kahnle | Oak | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 16.0 | .643 |
| Mitch Keller | | sp | 28 | 34 | 4 | .118 | 1 | 18 | .529 | 134 | 3.9 | 17 | 3 | .176 | 98.8 | .647 |
| Antoine Kelly* | Atl | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 3 | .750 | 18.2 | .593 |
| Joe Kelly | LAA | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 16.9 | .617 |
| Kevin Kelly | | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 6 | .261 | 17.9 | .668 |
| Merrill Kelly | Det | sp | 35 | 15 | 2 | .133 | 2 | 11 | .733 | 82 | 5.5 | 9 | 1 | .111 | 106.7 | .663 |
| Michael Kelly | Bal | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 23.4 | .567 |
| Zack Kelly | Bal | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 3 | .214 | 27.4 | .533 |
| Orion Kerkering | Bos | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 5 | .238 | 20.2 | .657 |
| Ray Kerr* | LAA | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 15.8 | .603 |
| Brett Kerry | NYA | sp | 25 | 13 | 0 | .000 | 0 | 6 | .462 | 60 | 4.6 | 9 | 2 | .222 | 62.1 | .611 |
| Clayton Kershaw* | LAA | sp | 36 | 6 | 0 | .000 | 0 | 6 | 1.000 | 28 | 4.7 | 0 | 0 | .000 | 100.7 | .690 |
| Yusei Kikuchi* | NYN | sp | 33 | 32 | 2 | .063 | 1 | 21 | .656 | 136 | 4.3 | 11 | 1 | .091 | 97.9 | .647 |
| Craig Kimbrel | | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 18.9 | .598 |
| John King* | StL | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 17.9 | .683 |
| Michael King | Tam | mr | 29 | 32 | 0 | .000 | 0 | 13 | .406 | 137 | 4.3 | 22 | 7 | .318 | 93.1 | .626 |
| George Kirby | Sea | sp | 26 | 32 | 0 | .000 | 0 | 18 | .563 | 140 | 4.4 | 15 | 4 | .267 | 91.4 | .694 |
| Andrew Kittredge | ChN | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 19.3 | .662 |
| Will Klein | Mia | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 31.3 | .580 |
| Jared Koenig* | Tam | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.8 | .609 |
| Michael Kopech | SF | sp | 28 | 14 | 0 | .000 | 0 | 5 | .357 | 68 | 4.9 | 16 | 6 | .375 | 79.3 | .573 |
| Dean Kremer | Det | sp | 28 | 34 | 2 | .059 | 2 | 21 | .618 | 117 | 3.4 | 10 | 2 | .200 | 101.8 | .639 |
| Alex Lange | LAN | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 6 | .750 | 20.7 | .610 |
| Jake Latz* | Phi | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 14.3 | .682 |
| Nate Lavender* | ChA | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 13 | .406 | 21.8 | .611 |
| Justin Lawrence | Bos | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 20.7 | .596 |
| Max Lazar | NYA | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 9 | .391 | 22.8 | .668 |
| Jose Leclerc | Pit | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 2 | .080 | 20.3 | .594 |
| Dylan Lee* | | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 17.3 | .641 |
| Jack Leiter | SF | sp | 24 | 13 | 0 | .000 | 0 | 2 | .154 | 45 | 3.5 | 22 | 14 | .636 | 52.6 | .594 |
| Mark Leiter | Bos | mr | 33 | 2 | 0 | .000 | 0 | 2 | 1.000 | 6 | 3.0 | 15 | 3 | .200 | 24.2 | .616 |
| Matthew Liberatore* | | sp | 24 | 18 | 1 | .056 | 0 | 14 | .778 | 58 | 3.2 | 13 | 3 | .231 | 87.5 | .623 |
| Yu-Min Lin* | Bal | sp | 20 | 29 | 0 | .000 | 0 | 11 | .379 | 162 | 5.6 | 28 | 8 | .286 | 59.2 | .607 |
| Zack Littell | Cle | mr | 28 | 23 | 0 | .000 | 0 | 13 | .565 | 111 | 4.8 | 16 | 6 | .375 | 75.4 | .666 |
| Brendon Little* | LAN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 2 | .077 | 21.0 | .602 |
| Luke Little* | Hou | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 19.0 | .583 |
| Ben Lively | | sp | 32 | 23 | 0 | .000 | 0 | 11 | .478 | 85 | 3.7 | 14 | 6 | .429 | 97.8 | .635 |
| Mauricio Llovera | StL | mr | 28 | 6 | 0 | .000 | 0 | 1 | .167 | 23 | 3.8 | 9 | 2 | .222 | 39.1 | .662 |
| Jonathan Loaisiga | Ari | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 18.0 | .715 |
| Nick Lodolo* | | sp | 26 | 9 | 0 | .000 | 0 | 6 | .667 | 35 | 3.9 | 2 | 1 | .500 | 91.2 | .660 |
| Pablo Lopez | Tex | sp | 28 | 34 | 2 | .059 | 0 | 22 | .647 | 155 | 4.6 | 19 | 4 | .211 | 104.2 | .662 |
| Reynaldo Lopez | LAA | mr | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 16 | 4 | .250 | 23.1 | .625 |
| Michael Lorenzen | LAA | sp | 32 | 12 | 0 | .000 | 0 | 7 | .583 | 38 | 3.2 | 11 | 0 | .000 | 54.7 | .642 |
| Ryan Loutos | Mia | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 18.0 | .611 |
| Richard Lovelady* | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 2 | .167 | 14.3 | .637 |
| Seth Lugo | NYN | sp | 34 | 32 | 3 | .094 | 1 | 19 | .594 | 167 | 5.2 | 6 | 5 | .833 | 97.3 | .661 |
| Jesus Luzardo* | Cle | sp | 26 | 15 | 0 | .000 | 0 | 11 | .733 | 92 | 6.1 | 3 | 1 | .333 | 99.7 | .634 |
| Daniel Lynch* | Phi | sp | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 1 | 1 | 1.000 | 103.0 | .573 |
| Lance Lynn | LAN | sp | 37 | 32 | 2 | .063 | 1 | 19 | .594 | 122 | 3.8 | 16 | 7 | .438 | 99.0 | .647 |
| Adam Macko* | | sp | 23 | 5 | 0 | .000 | 0 | 0 | .000 | 6 | 1.2 | 17 | 4 | .235 | 37.2 | .573 |
| Kenta Maeda | Mil | sp | 36 | 2 | 0 | .000 | 0 | 2 | 1.000 | 10 | 5.0 | 1 | 1 | 1.000 | 91.0 | .659 |
| Tyler Mahle | Ari | sp | 29 | 2 | 0 | .000 | 0 | 2 | 1.000 | 7 | 3.5 | 0 | 0 | .000 | 107.5 | .614 |
| Anthony Maldonado | Tor | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 35 | 10 | .286 | 21.0 | .638 |
| Matt Manning | Mia | sp | 26 | 14 | 1 | .071 | 1 | 11 | .786 | 63 | 4.5 | 7 | 1 | .143 | 78.8 | .626 |
| Alek Manoah | Sea | sp | 26 | 4 | 0 | .000 | 0 | 2 | .500 | 17 | 4.3 | 2 | 1 | .500 | 92.8 | .631 |
| Joe Mantiply* | KC | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 6 | .333 | 13.9 | .649 |
| Ron Marinaccio | ChA | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 41 | 13 | .317 | 18.0 | .586 |
| German Marquez | Bos | sp | 29 | 2 | 1 | .500 | 1 | 2 | 1.000 | 9 | 4.5 | 0 | 0 | .000 | 123.0 | .646 |
| Alec Marsh | | sp | 26 | 9 | 0 | .000 | 0 | 5 | .556 | 37 | 4.1 | 23 | 7 | .304 | 40.1 | .619 |
| Chris Martin | ChN | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 18.7 | .699 |
| Davis Martin | SD | sp | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 0 | 0 | .000 | 93.0 | .602 |
| Justin Martinez | Tex | mr | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 12 | .429 | 19.1 | .542 |
| Nick Martinez | Mil | mr | 33 | 32 | 1 | .031 | 1 | 21 | .656 | 138 | 4.3 | 12 | 3 | .250 | 98.0 | .643 |
| Seth Martinez | Hou | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 42 | 17 | .405 | 20.9 | .633 |
| Phil Maton | | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 6 | .240 | 19.4 | .610 |
| Yuki Matsui* | NYN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 1 | .059 | 21.1 | .592 |
| Steven Matz* | | sp | 33 | 6 | 0 | .000 | 0 | 3 | .500 | 40 | 6.7 | 9 | 2 | .222 | 48.9 | .631 |
| Tyler Matzek* | SD | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 16.4 | .602 |
| Tim Mayza* | | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 14.6 | .649 |
| James McArthur | Det | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 20.4 | .650 |
| Chayce McDermott | LAN | sp | 25 | 32 | 1 | .031 | 1 | 12 | .375 | 126 | 3.9 | 18 | 7 | .389 | 89.1 | .594 |
| Griff McGarry | Bal | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 9 | .281 | 21.6 | .550 |
| Scott McGough | Hou | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 16.5 | .626 |
| Michael McGreevy | ChA | sp | 23 | 2 | 0 | .000 | 0 | 2 | 1.000 | 10 | 5.0 | 1 | 0 | .000 | 25.6 | .680 |
| Evan McKendry | SD | sp | 26 | 10 | 0 | .000 | 0 | 7 | .700 | 43 | 4.3 | 5 | 1 | .200 | 70.0 | .660 |
| Triston McKenzie | | sp | 26 | 34 | 1 | .029 | 0 | 20 | .588 | 171 | 5.0 | 17 | 7 | .412 | 96.6 | .642 |
| John McMillon | Pit | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 31.8 | .535 |
| John Means* | Tex | sp | 31 | 2 | 0 | .000 | 0 | 2 | 1.000 | 5 | 2.5 | 0 | 0 | .000 | 93.5 | .658 |
| Nick Mears | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 2 | 1.000 | 23.5 | .496 |
| Trevor Megill | | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 | 18.9 | .623 |
| Tylor Megill | NYN | sp | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 27.3 | .707 |
| Juan M. Mejia | Mia | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.3 | .577 |
| Cristian Mena | Col | sp | 21 | 23 | 1 | .043 | 1 | 5 | .217 | 88 | 3.8 | 13 | 8 | .615 | 89.3 | .611 |
| Michael Mercado | NYA | mr | 25 | 9 | 0 | .000 | 0 | 4 | .444 | 36 | 4.0 | 7 | 4 | .571 | 77.3 | .604 |
| Julian Merryweather | | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 22.1 | .660 |
| Max Meyer | ChA | sp | 25 | 32 | 1 | .031 | 0 | 13 | .406 | 150 | 4.7 | 19 | 5 | .263 | 89.9 | .614 |
| Miles Mikolas | StL | sp | 35 | 34 | 7 | .206 | 2 | 24 | .706 | 153 | 4.5 | 14 | 3 | .214 | 96.8 | .675 |
| Bobby Miller | Bal | sp | 25 | 27 | 1 | .037 | 0 | 15 | .556 | 146 | 5.4 | 24 | 5 | .208 | 81.5 | .639 |
| Bryce Miller | | sp | 25 | 36 | 2 | .056 | 1 | 24 | .667 | 131 | 3.6 | 13 | 6 | .462 | 93.5 | .658 |
| Erik Miller* | | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 0 | .000 | 34.4 | .572 |
| Mason Miller | Bos | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 | 21.2 | .616 |
| Tyson Miller | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 | 19.4 | .632 |
| Hoby Milner* | Cin | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 15.4 | .646 |
| A.J. Minter* | Was | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 16.5 | .671 |
| Andrew Misiaszek* | Cin | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 17.0 | .580 |
| Jacob Misiorowski | Tex | sp | 22 | 7 | 0 | .000 | 0 | 0 | .000 | 26 | 3.7 | 10 | 3 | .300 | 57.0 | .546 |
| Casey Mize | | sp | 27 | 20 | 0 | .000 | 0 | 13 | .650 | 97 | 4.8 | 12 | 2 | .167 | 100.3 | .650 |
| Sam Moll* | Tor | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 14.8 | .650 |
| Frankie Montas | ChN | sp | 31 | 11 | 0 | .000 | 0 | 6 | .545 | 41 | 3.7 | 10 | 1 | .100 | 94.1 | .640 |
| Keider Montero | | sp | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 22.8 | .665 |
| Jordan Montgomery* | | sp | 31 | 32 | 0 | .000 | 0 | 21 | .656 | 174 | 5.4 | 18 | 8 | .444 | 100.4 | .650 |
| Matt Moore* | Min | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 6 | .500 | 19.1 | .630 |
| Francisco Morales | LAN | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 20.8 | .575 |
| Adrian Morejon* | | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 15.8 | .646 |
| Eli Morgan | Det | mr | 28 | 21 | 0 | .000 | 0 | 13 | .619 | 83 | 4.0 | 9 | 4 | .444 | 91.0 | .654 |
| Charlie Morton | SD | sp | 40 | 31 | 2 | .065 | 1 | 21 | .677 | 151 | 4.9 | 12 | 3 | .250 | 109.0 | .605 |
| Kyle Muller* | Tor | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 2 | .133 | 18.8 | .605 |
| Andres Munoz | Sea | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 6 | .222 | 18.8 | .615 |
| Roddery Munoz | Tex | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 19.7 | .542 |
| Ryan Murphy | SF | sp | 24 | 12 | 0 | .000 | 0 | 4 | .333 | 57 | 4.8 | 5 | 2 | .400 | 81.0 | .620 |
| Joe Musgrove | | sp | 31 | 17 | 3 | .176 | 0 | 10 | .588 | 78 | 4.6 | 14 | 6 | .429 | 106.6 | .647 |
| Tobias Myers | | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 20.6 | .621 |
| Andrew Nardi* | Atl | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 20.2 | .610 |
| Nick Nastrini | SD | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 0 | 0 | .000 | 83.0 | .663 |
| Packy Naughton* | Was | sp | 28 | 11 | 0 | .000 | 0 | 6 | .545 | 70 | 6.4 | 1 | 1 | 1.000 | 68.6 | .641 |
| Jack Neely | | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 7 | .350 | 22.8 | .594 |
| Kyle Nelson* | Atl | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 14.1 | .646 |
| Ryne Nelson | Cin | sp | 26 | 25 | 0 | .000 | 0 | 13 | .520 | 102 | 4.1 | 16 | 5 | .313 | 84.6 | .653 |
| Hector Neris | Cin | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 3 | .115 | 17.9 | .624 |
| Kyle Nicolas | Atl | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 4 | .200 | 21.6 | .577 |
| Aaron Nola | Cle | sp | 31 | 33 | 4 | .121 | 3 | 24 | .727 | 158 | 4.8 | 11 | 1 | .091 | 105.3 | .673 |
| Dedniel Nunez | Tex | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 12 | .387 | 22.7 | .602 |
| Bailey Ober | | sp | 28 | 25 | 0 | .000 | 0 | 13 | .520 | 131 | 5.2 | 6 | 0 | .000 | 85.8 | .664 |
| Pierson Ohl | KC | sp | 24 | 31 | 3 | .097 | 0 | 16 | .516 | 138 | 4.5 | 10 | 2 | .200 | 92.9 | .702 |
| Shohei Ohtani | Tex | dh | 29 | 3 | 0 | .000 | 0 | 1 | .333 | 19 | 6.3 | 2 | 0 | .000 | 97.7 | .659 |
| Steven Okert* | KC | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 4 | .174 | 16.2 | .630 |
| Mat Olsen | NYN | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 5 | .227 | 22.4 | .623 |
| Reese Olson | | sp | 24 | 15 | 0 | .000 | 0 | 5 | .333 | 76 | 5.1 | 10 | 6 | .600 | 65.3 | .613 |
| Kaleb Ort | Hou | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 13.4 | .589 |
| Luis L. Ortiz | | sp | 25 | 5 | 0 | .000 | 0 | 1 | .200 | 12 | 2.4 | 22 | 10 | .455 | 30.9 | .584 |
| Michel Otanez | Tex | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 16.2 | .515 |
| Adam Ottavino | SD | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 10 | .417 | 21.4 | .586 |
| Chris Paddack | | sp | 28 | 23 | 0 | .000 | 0 | 14 | .609 | 126 | 5.5 | 9 | 4 | .444 | 87.5 | .666 |
| Emilio Pagan | ChA | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 | 15.3 | .628 |
| Daniel Palencia | Mia | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 1 | 1.000 | 25.0 | .600 |
| Andre Pallante | Min | mr | 25 | 5 | 1 | .200 | 0 | 3 | .600 | 31 | 6.2 | 16 | 4 | .250 | 26.1 | .644 |
| Carson Palmquist* | Ari | sp | 23 | 1 | 0 | .000 | 0 | 1 | 1.000 | 4 | 4.0 | 5 | 0 | .000 | 29.6 | .610 |
| Enoli Paredes | NYA | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 7 | .333 | 19.8 | .569 |
| Mitchell Parker* | Atl | sp | 24 | 24 | 1 | .042 | 0 | 5 | .208 | 103 | 4.3 | 18 | 3 | .167 | 62.0 | .611 |
| Joel Payamps | Cin | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 | 22.7 | .609 |
| Nate Pearson | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 37 | 9 | .243 | 23.3 | .593 |
| Elvis Peguero | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 7 | .583 | 21.4 | .641 |
| Walter Pennington* | | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 26.1 | .604 |
| Ryan Pepiot | | sp | 26 | 30 | 0 | .000 | 0 | 15 | .500 | 100 | 3.3 | 13 | 3 | .231 | 77.4 | .606 |
| Freddy Peralta | | sp | 28 | 33 | 2 | .061 | 0 | 17 | .515 | 172 | 5.2 | 22 | 4 | .182 | 100.6 | .622 |
| Wandy Peralta* | SD | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 2 | .133 | 17.6 | .579 |
| Cionel Perez* | Mil | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 10.8 | .538 |
| Martin Perez* | LAN | sp | 33 | 32 | 5 | .156 | 1 | 21 | .656 | 134 | 4.2 | 16 | 3 | .188 | 97.9 | .659 |
| Jack Perkins | Bal | sp | 26 | 1 | 0 | .000 | 0 | 1 | 1.000 | 2 | 2.0 | 3 | 0 | .000 | 32.8 | .580 |
| David Peterson* | Oak | sp | 28 | 22 | 0 | .000 | 0 | 12 | .545 | 93 | 4.2 | 12 | 2 | .167 | 93.5 | .620 |
| Brandon Pfaadt | Col | sp | 25 | 31 | 2 | .065 | 0 | 18 | .581 | 164 | 5.3 | 22 | 7 | .318 | 83.9 | .652 |
| Evan Phillips | Mil | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 0 | .000 | 18.8 | .647 |
| Nick Pivetta | Was | sp | 31 | 18 | 0 | .000 | 0 | 9 | .500 | 59 | 3.3 | 8 | 5 | .625 | 97.1 | .632 |
| Colin Poche* | Col | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 17.4 | .603 |
| Cade Povich* | Bos | sp | 24 | 27 | 0 | .000 | 0 | 13 | .481 | 129 | 4.8 | 19 | 9 | .474 | 97.4 | .613 |
| Ryan Pressly | Cin | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 0 | .000 | 15.9 | .656 |
| A.J. Puk* | LAN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 14.2 | .683 |
| Jose Quijada* | Mia | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 18.9 | .583 |
| Jose Quintana* | Pit | sp | 35 | 25 | 2 | .080 | 1 | 14 | .560 | 81 | 3.2 | 13 | 4 | .308 | 96.4 | .639 |
| Cole Ragans* | Was | sp | 26 | 17 | 0 | .000 | 0 | 9 | .529 | 85 | 5.0 | 9 | 5 | .556 | 101.4 | .662 |
| Taylor Rashi | ChN | mr | 28 | 15 | 0 | .000 | 0 | 8 | .533 | 70 | 4.7 | 6 | 0 | .000 | 82.6 | .601 |
| Drew Rasmussen | Bos | sp | 28 | 9 | 0 | .000 | 0 | 7 | .778 | 24 | 2.7 | 5 | 0 | .000 | 97.9 | .617 |
| Robbie Ray* | StL | sp | 32 | 6 | 1 | .167 | 1 | 2 | .333 | 28 | 4.7 | 6 | 0 | .000 | 96.8 | .654 |
| Marco Raya | Mia | sp | 21 | 11 | 0 | .000 | 0 | 4 | .364 | 46 | 4.2 | 4 | 2 | .500 | 62.6 | .619 |
| Colin Rea | Mil | sp | 33 | 5 | 0 | .000 | 0 | 3 | .600 | 19 | 3.8 | 2 | 2 | 1.000 | 83.8 | .670 |
| Sean Reid-Foley | | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 22.2 | .550 |
| Sean Reynolds | Mia | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 32.7 | .541 |
| Trevor Richards | NYN | mr | 31 | 33 | 0 | .000 | 0 | 10 | .303 | 174 | 5.3 | 22 | 3 | .136 | 91.8 | .615 |
| Sem Robberse | Pit | sp | 22 | 31 | 3 | .097 | 1 | 18 | .581 | 106 | 3.4 | 22 | 3 | .136 | 92.8 | .630 |
| Ethan Roberts | Oak | mr | 26 | 3 | 0 | .000 | 0 | 0 | .000 | 15 | 5.0 | 10 | 4 | .400 | 24.9 | .646 |
| David Robertson | | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 18.7 | .589 |
| Nick Robertson | Cin | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 19.9 | .642 |
| Joe Rock* | Cle | sp | 23 | 19 | 1 | .053 | 1 | 16 | .842 | 94 | 4.9 | 9 | 1 | .111 | 97.2 | .632 |
| Carlos Rodon* | ChA | sp | 31 | 33 | 1 | .030 | 0 | 19 | .576 | 98 | 3.0 | 19 | 5 | .263 | 101.9 | .626 |
| Carlos F. Rodriguez | Tor | sp | 22 | 2 | 0 | .000 | 0 | 0 | .000 | 11 | 5.5 | 7 | 3 | .429 | 27.6 | .634 |
| Eduardo Rodriguez* | Min | sp | 31 | 10 | 0 | .000 | 0 | 3 | .300 | 46 | 4.6 | 9 | 6 | .667 | 83.8 | .631 |
| Grayson Rodriguez | Tex | sp | 24 | 22 | 1 | .045 | 0 | 15 | .682 | 109 | 5.0 | 4 | 2 | .500 | 100.2 | .641 |
| Manuel Rodriguez | Pit | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 24.2 | .600 |
| Randy Rodriguez | Hou | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 16.8 | .597 |
| Yariel Rodriguez | ChN | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 14 | 7 | .500 | 21.4 | .627 |
| Yerry Rodriguez | LAN | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 9 | .375 | 16.0 | .610 |
| Taylor Rogers* | Ari | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 15.0 | .664 |
| Trevor Rogers* | SF | sp | 26 | 14 | 1 | .071 | 0 | 7 | .500 | 55 | 3.9 | 11 | 4 | .364 | 62.8 | .653 |
| Tyler Rogers | StL | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 3 | .158 | 17.3 | .682 |
| Jordan Romano | Cle | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 18.6 | .635 |
| JoJo Romero* | | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 7 | 7.0 | 14 | 6 | .429 | 18.5 | .656 |
| Landen Roupp | | sp | 25 | 16 | 0 | .000 | 0 | 6 | .375 | 67 | 4.2 | 18 | 3 | .167 | 51.0 | .613 |
| Jackson Rutledge | SF | sp | 25 | 11 | 1 | .091 | 0 | 6 | .545 | 39 | 3.5 | 9 | 1 | .111 | 114.7 | .635 |
| Joe Ryan | Mia | sp | 28 | 27 | 2 | .074 | 1 | 18 | .667 | 119 | 4.4 | 13 | 3 | .231 | 100.4 | .649 |
| Andrew Saalfrank* | Mia | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 21.1 | .602 |
| Chris Sale* | LAA | sp | 35 | 27 | 0 | .000 | 0 | 17 | .630 | 145 | 5.4 | 12 | 6 | .500 | 87.3 | .654 |
| Cristopher Sanchez* | Tam | sp | 27 | 32 | 0 | .000 | 0 | 24 | .750 | 135 | 4.2 | 13 | 1 | .077 | 92.0 | .666 |
| Nick Sandlin | Atl | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 7 | .389 | 19.7 | .606 |
| Patrick Sandoval* | | sp | 27 | 2 | 0 | .000 | 0 | 1 | .500 | 14 | 7.0 | 25 | 8 | .320 | 22.6 | .627 |
| Cole Sands | | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 4 | .174 | 17.0 | .628 |
| Tony Santillan | Col | mr | 27 | 5 | 0 | .000 | 0 | 3 | .600 | 20 | 4.0 | 5 | 0 | .000 | 33.1 | .553 |
| Gregory Santos | LAA | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 16.6 | .631 |
| Tayler Saucedo* | Mil | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 5 | .417 | 18.3 | .638 |
| Josh Sborz | SD | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 19.9 | .626 |
| Max Scherzer | | sp | 39 | 6 | 0 | .000 | 0 | 4 | .667 | 23 | 3.8 | 3 | 1 | .333 | 97.8 | .654 |
| Clarke Schmidt | Col | sp | 28 | 19 | 1 | .053 | 1 | 8 | .421 | 72 | 3.8 | 17 | 14 | .824 | 96.4 | .598 |
| John Schreiber | ChA | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 22.3 | .623 |
| Christian Scott | | sp | 25 | 21 | 0 | .000 | 0 | 13 | .619 | 77 | 3.7 | 12 | 5 | .417 | 90.2 | .637 |
| Tanner Scott* | NYN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 6 | .240 | 21.9 | .627 |
| Tayler Scott | Phi | mr | 32 | 3 | 0 | .000 | 0 | 0 | .000 | 8 | 2.7 | 13 | 5 | .385 | 32.6 | .572 |
| JP Sears* | Cin | sp | 28 | 12 | 0 | .000 | 0 | 5 | .417 | 54 | 4.5 | 12 | 3 | .250 | 56.1 | .620 |
| Luis Severino | Tex | sp | 30 | 32 | 1 | .031 | 0 | 10 | .313 | 129 | 4.0 | 17 | 9 | .529 | 94.4 | .630 |
| Paul Sewald | LAA | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 4 | .267 | 19.6 | .616 |
| Ian Seymour* | Mia | sp | 25 | 4 | 0 | .000 | 0 | 2 | .500 | 34 | 8.5 | 3 | 3 | 1.000 | 78.5 | .659 |
| Davis Sharpe | Atl | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 4 | .174 | 21.4 | .657 |
| Chase Silseth | Sea | sp | 24 | 9 | 0 | .000 | 0 | 6 | .667 | 43 | 4.8 | 4 | 1 | .250 | 90.3 | .622 |
| Lucas Sims | Col | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 7 | .318 | 22.8 | .572 |
| Brady Singer | LAN | sp | 27 | 33 | 3 | .091 | 1 | 24 | .727 | 103 | 3.1 | 10 | 1 | .100 | 107.1 | .646 |
| Tarik Skubal* | Tam | sp | 27 | 34 | 2 | .059 | 1 | 19 | .559 | 142 | 4.2 | 20 | 10 | .500 | 94.6 | .657 |
| Cade Smith | Tam | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 9 | .346 | 21.2 | .593 |
| Drew Smith | NYN | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 20.4 | .627 |
| Will Smith* | ChN | cl | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 4 | .235 | 17.8 | .607 |
| AJ Smith-Shawver | Tex | sp | 21 | 7 | 0 | .000 | 0 | 1 | .143 | 41 | 5.9 | 11 | 4 | .364 | 39.8 | .581 |
| Blake Snell* | Cin | sp | 31 | 26 | 0 | .000 | 0 | 10 | .385 | 129 | 5.0 | 18 | 5 | .278 | 100.8 | .599 |
| Robby Snelling* | Bal | sp | 20 | 28 | 0 | .000 | 0 | 10 | .357 | 134 | 4.8 | 41 | 11 | .268 | 55.4 | .607 |
| Collin Snider | Bos | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 29.3 | .620 |
| Jose Soriano | | mr | 25 | 23 | 0 | .000 | 0 | 6 | .261 | 79 | 3.4 | 20 | 3 | .150 | 68.1 | .604 |
| Mike Soroka | Ari | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 17.3 | .659 |
| Gregory Soto* | Cle | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 7 | .368 | 16.2 | .632 |
| Gabe Speier* | Was | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 | 19.3 | .667 |
| Mitch Spence | SF | sp | 26 | 16 | 0 | .000 | 0 | 9 | .563 | 48 | 3.0 | 5 | 3 | .600 | 99.5 | .634 |
| Carson Spiers | Cle | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 13.5 | .704 |
| Jeffrey Springs* | Bos | sp | 31 | 8 | 1 | .125 | 0 | 6 | .750 | 41 | 5.1 | 2 | 0 | .000 | 103.5 | .663 |
| Garrett Stallings | LAA | sp | 26 | 9 | 0 | .000 | 0 | 5 | .556 | 40 | 4.4 | 7 | 2 | .286 | 63.7 | .633 |
| Ryne Stanek | | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 7 | .500 | 18.1 | .629 |
| Cody Stashak | Cle | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 | 18.9 | .651 |
| Josh Staumont | Phi | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 19.4 | .568 |
| Justin Steele* | Tex | sp | 28 | 26 | 1 | .038 | 0 | 16 | .615 | 127 | 4.9 | 9 | 2 | .222 | 99.6 | .640 |
| Brock Stewart | Tex | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 2 | .400 | 15.1 | .636 |
| Gavin Stone | | sp | 25 | 13 | 0 | .000 | 0 | 7 | .538 | 58 | 4.5 | 22 | 5 | .227 | 35.8 | .642 |
| Matt Strahm* | Tor | mr | 32 | 16 | 0 | .000 | 0 | 8 | .500 | 86 | 5.4 | 14 | 4 | .286 | 47.9 | .631 |
| Hunter Stratton | | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 19.2 | .577 |
| Spencer Strider | Sea | sp | 25 | 2 | 0 | .000 | 0 | 2 | 1.000 | 12 | 6.0 | 1 | 0 | .000 | 105.0 | .590 |
| Marcus Stroman | Tam | sp | 33 | 33 | 1 | .030 | 1 | 18 | .545 | 146 | 4.4 | 24 | 10 | .417 | 95.2 | .637 |
| Peter Strzelecki | KC | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 7 | .212 | 17.5 | .629 |
| Jose Suarez* | | sp | 26 | 5 | 0 | .000 | 0 | 2 | .400 | 23 | 4.6 | 12 | 3 | .250 | 40.7 | .639 |
| Ranger Suarez* | ChN | sp | 28 | 30 | 1 | .033 | 0 | 20 | .667 | 119 | 4.0 | 16 | 4 | .250 | 100.3 | .633 |
| Robert Suarez | Tam | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 7 | .292 | 17.1 | .593 |
| Brent Suter* | LAN | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 20.7 | .647 |
| Erik Swanson | SD | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 15.9 | .657 |
| Devin Sweet | Oak | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 23.4 | .635 |
| Jameson Taillon | Tam | sp | 32 | 27 | 2 | .074 | 1 | 17 | .630 | 114 | 4.2 | 8 | 4 | .500 | 94.8 | .644 |
| Dillon Tate | StL | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 19.8 | .606 |
| Dylan Tebrake | SD | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 | 21.3 | .610 |
| Caleb Thielbar* | Pit | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 16.1 | .641 |
| Ryan Thompson | Bos | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 5 | .294 | 17.9 | .622 |
| Zack Thompson* | SF | sp | 26 | 8 | 0 | .000 | 0 | 6 | .750 | 34 | 4.3 | 25 | 5 | .200 | 30.4 | .582 |
| Trent Thornton | Mil | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 21.0 | .638 |
| Ricky Tiedemann* | Tex | sp | 21 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 19.7 | .636 |
| Michael Tonkin | NYN | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 10.0 | .550 |
| Blake Treinen | Pit | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 19.5 | .626 |
| Edwin Uceta | Pit | mr | 26 | 2 | 0 | .000 | 0 | 0 | .000 | 8 | 4.0 | 5 | 2 | .400 | 32.8 | .604 |
| Abner Uribe | Sea | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 22.4 | .553 |
| Framber Valdez* | LAA | sp | 30 | 29 | 4 | .138 | 3 | 20 | .690 | 146 | 5.0 | 15 | 6 | .400 | 99.0 | .657 |
| Reid VanScoter* | KC | sp | 25 | 30 | 4 | .133 | 1 | 14 | .467 | 87 | 2.9 | 14 | 4 | .286 | 99.4 | .674 |
| Louie Varland | Atl | sp | 26 | 21 | 0 | .000 | 0 | 10 | .476 | 98 | 4.7 | 31 | 13 | .419 | 56.4 | .642 |
| Mike Vasil | Ari | sp | 24 | 23 | 0 | .000 | 0 | 13 | .565 | 97 | 4.2 | 21 | 6 | .286 | 71.8 | .637 |
| Randy Vasquez | Det | sp | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 3 | 1.5 | 0 | 0 | .000 | 57.3 | .624 |
| Justin Verlander | SD | sp | 41 | 16 | 2 | .125 | 1 | 11 | .688 | 71 | 4.4 | 5 | 0 | .000 | 103.6 | .634 |
| Alex Vesia* | Atl | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 11 | .379 | 18.3 | .603 |
| Nick Vespi* | Det | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 | 21.5 | .649 |
| Will Vest | | mr | 29 | 2 | 0 | .000 | 0 | 0 | .000 | 5 | 2.5 | 14 | 9 | .643 | 22.7 | .625 |
| Thyago Vieira | Mia | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 11.7 | .657 |
| Darius Vines | Tor | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 3 | .500 | 16.5 | .610 |
| Victor Vodnik | NYA | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 7 | .583 | 18.2 | .583 |
| Austin Voth | NYN | mr | 32 | 32 | 0 | .000 | 0 | 14 | .438 | 162 | 5.1 | 17 | 3 | .176 | 79.9 | .633 |
| Michael Wacha | | sp | 32 | 9 | 0 | .000 | 0 | 4 | .444 | 39 | 4.3 | 13 | 4 | .308 | 44.4 | .647 |
| Hurston Waldrep | Atl | sp | 22 | 9 | 0 | .000 | 0 | 6 | .667 | 30 | 3.3 | 5 | 0 | .000 | 95.1 | .616 |
| Matt Waldron | | sp | 27 | 32 | 2 | .063 | 1 | 16 | .500 | 135 | 4.2 | 16 | 11 | .688 | 89.5 | .641 |
| Ryan Walker | | mr | 28 | 3 | 0 | .000 | 0 | 0 | .000 | 21 | 7.0 | 14 | 2 | .143 | 22.0 | .635 |
| Taijuan Walker | | sp | 31 | 8 | 0 | .000 | 0 | 5 | .625 | 28 | 3.5 | 4 | 0 | .000 | 96.1 | .637 |
| Blake Walston* | ChN | sp | 23 | 16 | 1 | .063 | 1 | 9 | .563 | 65 | 4.1 | 8 | 1 | .125 | 102.1 | .606 |
| Will Warren | ChN | sp | 25 | 5 | 0 | .000 | 0 | 3 | .600 | 23 | 4.6 | 8 | 4 | .500 | 26.8 | .615 |
| Ryan Weathers* | Col | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 2 | .200 | 23.3 | .641 |
| Luke Weaver | Tam | sp | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 2 | .143 | 15.5 | .624 |
| Jacob Webb | Mil | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 8 | .571 | 22.0 | .628 |
| Logan Webb | Oak | sp | 27 | 33 | 8 | .242 | 5 | 23 | .697 | 143 | 4.3 | 9 | 5 | .556 | 92.4 | .714 |
| Tyler Wells | StL | sp | 29 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 1 | 0 | .000 | 90.5 | .591 |
| Joey Wentz* | | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 22.8 | .639 |
| Hayden Wesneski | Col | sp | 26 | 8 | 0 | .000 | 0 | 5 | .625 | 43 | 5.4 | 14 | 9 | .643 | 36.4 | .615 |
| Zack Wheeler | | sp | 34 | 34 | 3 | .088 | 1 | 23 | .676 | 145 | 4.3 | 27 | 12 | .444 | 107.4 | .643 |
| Carson Whisenhunt* | KC | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 2 | 2.0 | 2 | 2 | 1.000 | 32.5 | .610 |
| Brendan White | Was | mr | 25 | 2 | 0 | .000 | 0 | 2 | 1.000 | 9 | 4.5 | 8 | 1 | .125 | 35.6 | .631 |
| Garrett Whitlock | Oak | mr | 28 | 4 | 0 | .000 | 0 | 1 | .250 | 16 | 4.0 | 3 | 0 | .000 | 95.8 | .616 |
| Jordan Wicks* | Tam | sp | 24 | 4 | 0 | .000 | 0 | 4 | 1.000 | 21 | 5.3 | 2 | 1 | .500 | 87.0 | .672 |
| Brad Wieck* | Cle | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 23.2 | .547 |
| Devin Williams | | cl | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 20.1 | .583 |
| Gavin Williams | Ari | sp | 24 | 2 | 0 | .000 | 0 | 2 | 1.000 | 9 | 4.5 | 2 | 0 | .000 | 38.5 | .595 |
| Brandon Williamson* | Col | sp | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 3 | 1.5 | 2 | 0 | .000 | 64.5 | .578 |
| Bryse Wilson | Tor | mr | 26 | 14 | 0 | .000 | 0 | 10 | .714 | 66 | 4.7 | 3 | 0 | .000 | 92.9 | .645 |
| Steven Wilson | Det | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 1 | .111 | 23.1 | .560 |
| Allan Winans | SD | sp | 28 | 20 | 0 | .000 | 0 | 14 | .700 | 105 | 5.3 | 7 | 2 | .286 | 71.9 | .643 |
| Josh Winckowski | KC | mr | 26 | 19 | 0 | .000 | 0 | 8 | .421 | 78 | 4.1 | 18 | 6 | .333 | 55.6 | .634 |
| Josh Winder | Mia | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 26.0 | .615 |
| Keaton Winn | SF | sp | 26 | 11 | 0 | .000 | 0 | 2 | .182 | 46 | 4.2 | 12 | 9 | .750 | 89.8 | .631 |
| Bryan Woo | Bos | sp | 24 | 21 | 2 | .095 | 2 | 13 | .619 | 128 | 6.1 | 8 | 2 | .250 | 90.4 | .638 |
| Alex Wood* | ChN | sp | 33 | 9 | 0 | .000 | 0 | 8 | .889 | 40 | 4.4 | 5 | 3 | .600 | 93.7 | .650 |
| Simeon Woods Richardso | | sp | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 5 | .385 | 21.5 | .623 |
| Yoshinobu Yamamoto | Col | sp | 25 | 16 | 0 | .000 | 0 | 9 | .563 | 72 | 4.5 | 10 | 2 | .200 | 94.4 | .646 |
| Kirby Yates | StL | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 23.1 | .563 |
| Huascar Ynoa | Mil | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 26.5 | .575 |
| Brandon Young | Hou | sp | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 12 | 4.0 | 3 | 1 | .333 | 57.0 | .612 |
| Ryan Zeferjahn | Bos | mr | 26 | 1 | 0 | .000 | 0 | 1 | 1.000 | 4 | 4.0 | 0 | 0 | .000 | 86.0 | .616 |
| Angel Zerpa* | Bal | sp | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 24.1 | .609 |
| Yosver Zulueta | Col | mr | 26 | 6 | 0 | .000 | 0 | 1 | .167 | 28 | 4.7 | 20 | 15 | .750 | 40.5 | .556 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | PCH/G | STR% |
| Andrew Abbott* | | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 95.0 | .619 |
| Mick Abel | Sea | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 92.2 | .642 |
| Bryan Abreu | Sea | mr | 27 | 4 | 2 | .500 | 0 | .000 | 11 | 42 | 15 | .357 | 65 | 65 | 19 | 20.2 | .617 |
| Jason Adam | Ari | mr | 32 | 10 | 8 | .800 | 2 | .200 | 15 | 28 | 7 | .250 | 65 | 65 | 27 | 20.0 | .635 |
| Austin L. Adams | Hou | mr | 33 | 0 | 0 | .000 | 0 | .000 | 4 | 10 | 2 | .200 | 12 | 12 | 2 | 16.6 | .528 |
| Ty Adcock | Det | mr | 27 | 37 | 32 | .865 | 4 | .108 | 3 | 23 | 5 | .217 | 61 | 61 | 52 | 15.8 | .682 |
| Keegan Akin* | LAA | mr | 29 | 5 | 4 | .800 | 1 | .200 | 7 | 20 | 9 | .450 | 43 | 43 | 16 | 18.6 | .649 |
| Jorge Alcala | Bal | mr | 28 | 19 | 15 | .789 | 4 | .211 | 11 | 61 | 11 | .180 | 87 | 87 | 54 | 19.3 | .620 |
| Franco Aleman | Col | mr | 24 | 7 | 3 | .429 | 4 | .571 | 5 | 20 | 6 | .300 | 33 | 31 | 13 | 27.3 | .627 |
| Scott Alexander* | | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 8 | 5 | 2 | 36.8 | .619 |
| Tyler Alexander* | ChA | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 33 | 2 | 0 | 89.8 | .687 |
| Logan T. Allen* | Was | sp | 25 | 2 | 1 | .500 | 1 | .500 | 0 | 5 | 3 | .600 | 28 | 4 | 4 | 88.6 | .630 |
| Jose Alvarado* | Ari | mr | 29 | 31 | 26 | .839 | 5 | .161 | 2 | 24 | 7 | .292 | 55 | 55 | 47 | 18.0 | .631 |
| Adbert Alzolay | ChN | cl | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 88.9 | .665 |
| Ian Anderson | Atl | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 103.2 | .600 |
| Nick Anderson | Was | mr | 33 | 5 | 3 | .600 | 2 | .400 | 4 | 20 | 8 | .400 | 40 | 40 | 20 | 21.5 | .658 |
| Tyler Anderson* | | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 98.4 | .656 |
| Luarbert Arias | Col | mr | 23 | 7 | 3 | .429 | 4 | .571 | 9 | 65 | 20 | .308 | 79 | 77 | 19 | 24.5 | .632 |
| Shawn Armstrong | Ari | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 82.4 | .647 |
| Spencer Arrighetti | | sp | 24 | 2 | 0 | .000 | 2 | 1.000 | 1 | 8 | 5 | .625 | 38 | 11 | 2 | 70.8 | .611 |
| Aaron Ashby* | SD | sp | 26 | 5 | 4 | .800 | 1 | .200 | 2 | 11 | 2 | .182 | 27 | 26 | 18 | 21.9 | .610 |
| Braxton Ashcraft | Atl | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 82.5 | .659 |
| Graham Ashcraft | Was | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 23 | 1 | 1 | 101.8 | .636 |
| Pedro Avila | | sp | 27 | 4 | 1 | .250 | 3 | .750 | 2 | 6 | 4 | .667 | 14 | 13 | 5 | 26.0 | .643 |
| Anthony Banda* | Mia | mr | 30 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 3 | 3 | 1 | 28.0 | .655 |
| Tanner Banks* | Tam | mr | 32 | 14 | 13 | .929 | 1 | .071 | 6 | 30 | 6 | .200 | 52 | 52 | 35 | 21.7 | .663 |
| Scott Barlow | ChN | mr | 31 | 5 | 3 | .600 | 2 | .400 | 6 | 28 | 5 | .179 | 47 | 47 | 14 | 23.5 | .629 |
| Jaime Barria | ChN | mr | 27 | 0 | 0 | .000 | 0 | .000 | 5 | 13 | 1 | .077 | 25 | 25 | 4 | 27.0 | .677 |
| Chris Bassitt | Mil | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 104.0 | .660 |
| Brady Basso* | Min | sp | 26 | 2 | 0 | .000 | 1 | .500 | 11 | 15 | 9 | .600 | 35 | 35 | 8 | 14.2 | .665 |
| Mike Baumann | Bal | mr | 28 | 4 | 2 | .500 | 2 | .500 | 4 | 4 | 0 | .000 | 17 | 17 | 6 | 21.7 | .575 |
| Jarod Bayless | Phi | mr | 27 | 2 | 1 | .500 | 1 | .500 | 0 | 6 | 3 | .500 | 9 | 9 | 2 | 23.0 | .614 |
| Shane Baz | Bal | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 2 | 0 | .000 | 38 | 9 | 1 | 71.5 | .618 |
| Eduard Bazardo | Pit | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 3 | 1 | 60.9 | .641 |
| David Bednar | Tam | cl | 29 | 26 | 17 | .654 | 9 | .346 | 2 | 25 | 5 | .200 | 49 | 49 | 35 | 20.1 | .620 |
| Jalen Beeks* | LAN | mr | 30 | 3 | 2 | .667 | 1 | .333 | 3 | 40 | 13 | .325 | 52 | 52 | 22 | 30.3 | .625 |
| Clayton Beeter | NYA | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 4 | 9 | 3 | .333 | 26 | 16 | 1 | 46.7 | .600 |
| Brayan Bello | Mil | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 95.5 | .635 |
| Anthony Bender | Mil | mr | 29 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 33 | 7 | 2 | 79.1 | .647 |
| Brennan Bernardino* | NYA | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 7 | 2 | 0 | .000 | 18 | 17 | 2 | 17.7 | .610 |
| Jose Berrios | Tor | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 99.8 | .661 |
| Prelander Berroa | SF | mr | 24 | 7 | 3 | .429 | 4 | .571 | 11 | 48 | 19 | .396 | 74 | 65 | 13 | 24.6 | .524 |
| Tanner Bibee | Was | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 100.9 | .638 |
| Phil Bickford | Mil | mr | 28 | 4 | 2 | .500 | 2 | .500 | 6 | 22 | 5 | .227 | 37 | 37 | 16 | 16.5 | .604 |
| Osvaldo Bido | Mia | sp | 28 | 1 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 6 | 6 | 2 | 25.5 | .601 |
| Shane Bieber | Tor | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 95.5 | .702 |
| Hunter Bigge | Sea | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 1 | 6 | 3 | .500 | 14 | 14 | 8 | 24.4 | .598 |
| Hayden Birdsong | Bos | sp | 22 | 0 | 0 | .000 | 0 | .000 | 5 | 14 | 7 | .500 | 32 | 22 | 5 | 38.0 | .589 |
| Mason Black | Min | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 2 | 2 | 1 | 45.5 | .648 |
| Ronel Blanco | Col | mr | 30 | 2 | 2 | 1.000 | 0 | .000 | 2 | 32 | 14 | .438 | 47 | 30 | 13 | 49.3 | .616 |
| Jonathan Bowlan | SF | sp | 27 | 9 | 5 | .556 | 4 | .444 | 7 | 40 | 12 | .300 | 51 | 43 | 12 | 28.6 | .616 |
| Joe Boyle | NYA | sp | 24 | 6 | 4 | .667 | 2 | .333 | 0 | 16 | 7 | .438 | 31 | 20 | 13 | 48.5 | .557 |
| Cody Bradford* | Tam | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 3 | 1.000 | 6 | 6 | 1 | 23.7 | .641 |
| Kyle Bradish | Bal | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 99.6 | .630 |
| Taj Bradley | | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 90.5 | .610 |
| Ryan Brasier | Pit | mr | 36 | 1 | 1 | 1.000 | 0 | .000 | 5 | 11 | 3 | .273 | 20 | 20 | 9 | 22.9 | .663 |
| Huascar Brazoban | NYN | mr | 34 | 2 | 1 | .500 | 1 | .500 | 0 | 5 | 1 | .200 | 8 | 8 | 4 | 23.3 | .629 |
| John Brebbia | ChA | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 1 | 8.5 | .765 |
| Beau Brieske | StL | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 94.5 | .624 |
| Trevor Brigden | Cin | mr | 28 | 2 | 1 | .500 | 1 | .500 | 0 | 25 | 7 | .280 | 32 | 32 | 16 | 17.9 | .594 |
| Jhony Brito | ChA | sp | 26 | 3 | 1 | .333 | 2 | .667 | 10 | 29 | 8 | .276 | 63 | 46 | 12 | 35.0 | .649 |
| Kyle Brnovich | StL | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 23 | 3 | 1 | 74.7 | .643 |
| T.J. Brock | Phi | mr | 24 | 5 | 2 | .400 | 3 | .600 | 0 | 9 | 4 | .444 | 13 | 13 | 7 | 22.7 | .590 |
| Ben Brown | Sea | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 86.8 | .622 |
| Hunter Brown | Hou | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 35 | 1 | 0 | 99.0 | .620 |
| Zach Brzykcy | Phi | mr | 24 | 6 | 3 | .500 | 2 | .333 | 7 | 33 | 13 | .394 | 50 | 49 | 12 | 25.8 | .582 |
| Kris Bubic* | Tex | sp | 26 | 5 | 4 | .800 | 0 | .000 | 1 | 14 | 1 | .071 | 19 | 14 | 5 | 36.5 | .620 |
| Walker Buehler | LAA | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 90.6 | .675 |
| Aaron Bummer* | Oak | mr | 30 | 3 | 2 | .667 | 1 | .333 | 13 | 10 | 4 | .400 | 40 | 40 | 12 | 16.7 | .616 |
| Brock Burke* | SD | mr | 27 | 5 | 2 | .400 | 3 | .600 | 9 | 18 | 7 | .389 | 36 | 36 | 15 | 20.0 | .661 |
| Sean Burke | LAA | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 8 | 4 | .500 | 7 | 7 | 2 | 17.7 | .540 |
| Corbin Burnes | Ari | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 36 | 0 | 0 | 112.7 | .638 |
| Mike Burrows | Tex | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 2 | 7 | 0 | .000 | 12 | 7 | 3 | 41.8 | .616 |
| Jose Butto | Sea | sp | 26 | 2 | 1 | .500 | 1 | .500 | 0 | 10 | 6 | .600 | 25 | 13 | 6 | 49.7 | .616 |
| Edward Cabrera | Atl | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 8 | 3 | .375 | 17 | 10 | 7 | 47.5 | .621 |
| Genesis Cabrera* | Tam | mr | 27 | 5 | 0 | .000 | 4 | .800 | 22 | 32 | 12 | .375 | 63 | 63 | 13 | 18.4 | .623 |
| Isaiah Campbell | Ari | mr | 26 | 2 | 1 | .500 | 1 | .500 | 5 | 13 | 3 | .231 | 20 | 20 | 8 | 18.0 | .660 |
| Griffin Canning | Cin | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 4 | 1 | 76.8 | .617 |
| Yennier Cano | ChN | mr | 30 | 38 | 30 | .789 | 8 | .211 | 5 | 26 | 7 | .269 | 68 | 68 | 54 | 17.1 | .658 |
| Joey Cantillo* | SF | sp | 24 | 5 | 3 | .600 | 1 | .200 | 11 | 60 | 20 | .333 | 82 | 69 | 11 | 32.3 | .573 |
| Luis Castillo | Bos | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 111.2 | .636 |
| Miguel Castro | Min | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 8 | 13 | 4 | .308 | 31 | 31 | 7 | 19.2 | .612 |
| Tim Cate* | LAN | mr | 26 | 0 | 0 | .000 | 0 | .000 | 3 | 21 | 7 | .333 | 24 | 24 | 13 | 16.4 | .591 |
| Dylan Cease | Mil | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 110.0 | .608 |
| Slade Cecconi | SD | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 98.5 | .672 |
| Andrew Chafin* | Oak | mr | 34 | 1 | 1 | 1.000 | 0 | .000 | 11 | 18 | 4 | .222 | 38 | 38 | 15 | 16.6 | .612 |
| Chandler Champlain | | sp | 24 | 2 | 1 | .500 | 0 | .000 | 0 | 10 | 0 | .000 | 22 | 10 | 4 | 66.9 | .629 |
| Aroldis Chapman* | LAA | mr | 36 | 15 | 11 | .733 | 3 | .200 | 18 | 26 | 1 | .038 | 60 | 60 | 22 | 17.1 | .581 |
| Jesse Chavez | ChA | mr | 40 | 10 | 8 | .800 | 2 | .200 | 18 | 33 | 11 | .333 | 79 | 74 | 27 | 19.6 | .622 |
| Aaron Civale | Min | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 96.0 | .646 |
| Emmanuel Clase | Sea | cl | 26 | 29 | 21 | .724 | 8 | .276 | 2 | 46 | 9 | .196 | 54 | 54 | 44 | 18.8 | .654 |
| Garrett Cleavinger* | Ari | mr | 30 | 8 | 4 | .500 | 3 | .375 | 17 | 36 | 9 | .250 | 66 | 66 | 14 | 19.7 | .611 |
| Alex Cobb | SD | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 92.4 | .680 |
| Isaac Coffey | Cin | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 24 | 0 | 0 | 95.2 | .640 |
| Gerrit Cole | Oak | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 102.3 | .641 |
| Luis Contreras | StL | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 2 | .222 | 22 | 22 | 10 | 30.7 | .633 |
| Roansy Contreras | Det | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 0 | 0 | 87.9 | .639 |
| Connor Cooke | Pit | mr | 24 | 5 | 0 | .000 | 5 | 1.000 | 5 | 26 | 9 | .346 | 47 | 34 | 13 | 41.4 | .615 |
| Nestor Cortes* | | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 97.1 | .663 |
| Tom Cosgrove* | | mr | 28 | 2 | 1 | .500 | 1 | .500 | 1 | 6 | 3 | .500 | 7 | 7 | 2 | 21.4 | .613 |
| Danny Coulombe* | Det | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 4 | .364 | 11 | 11 | 3 | 16.4 | .678 |
| Jake Cousins | Mil | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 4 | 4 | 0 | 27.3 | .541 |
| Austin Cox* | ChA | sp | 27 | 4 | 4 | 1.000 | 0 | .000 | 0 | 11 | 2 | .182 | 22 | 18 | 13 | 38.4 | .610 |
| Kutter Crawford | Det | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 84.3 | .649 |
| Garrett Crochet* | | mr | 25 | 10 | 3 | .300 | 6 | .600 | 9 | 37 | 11 | .297 | 51 | 51 | 17 | 19.4 | .612 |
| Declan Cronin | | mr | 26 | 5 | 3 | .600 | 2 | .400 | 14 | 37 | 10 | .270 | 59 | 59 | 17 | 17.2 | .635 |
| Hans Crouse | Sea | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 1 | 1 | 0 | 22.0 | .682 |
| Fernando Cruz | | mr | 34 | 1 | 1 | 1.000 | 0 | .000 | 3 | 11 | 4 | .364 | 15 | 15 | 5 | 19.9 | .624 |
| Hagen Danner | Cin | mr | 25 | 4 | 4 | 1.000 | 0 | .000 | 2 | 15 | 1 | .067 | 26 | 26 | 9 | 19.6 | .629 |
| Yu Darvish | | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 101.4 | .639 |
| Enyel De Los Santos | Mil | mr | 28 | 10 | 6 | .600 | 4 | .400 | 10 | 21 | 8 | .381 | 47 | 47 | 17 | 18.2 | .636 |
| Jacob deGrom | Cle | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 94.7 | .680 |
| Reid Detmers* | | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 94.0 | .638 |
| Chris Devenski | ChN | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 83.1 | .659 |
| Alexis Diaz | | cl | 27 | 4 | 1 | .250 | 2 | .500 | 18 | 27 | 6 | .222 | 51 | 51 | 16 | 19.6 | .600 |
| Edwin Diaz | | cl | 30 | 31 | 26 | .839 | 5 | .161 | 3 | 21 | 4 | .190 | 49 | 49 | 41 | 19.0 | .613 |
| Miguel Diaz | SD | mr | 29 | 0 | 0 | .000 | 0 | .000 | 3 | 16 | 3 | .188 | 27 | 27 | 11 | 25.8 | .603 |
| Yilber Diaz | | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 11 | 2 | 2 | 74.7 | .607 |
| Jake Diekman* | SD | mr | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 3 | 3 | 2 | 18.7 | .554 |
| Hunter Dobbins | Sea | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 84.3 | .669 |
| Seranthony Dominguez | Was | mr | 29 | 7 | 5 | .714 | 2 | .286 | 8 | 33 | 8 | .242 | 57 | 57 | 24 | 21.2 | .591 |
| Camilo Doval | Oak | cl | 26 | 33 | 30 | .909 | 3 | .091 | 1 | 34 | 10 | .294 | 56 | 56 | 51 | 20.2 | .610 |
| Shawn Dubin | Was | sp | 28 | 1 | 1 | 1.000 | 0 | .000 | 0 | 4 | 3 | .750 | 16 | 5 | 5 | 70.1 | .613 |
| Dane Dunning | LAA | sp | 29 | 4 | 4 | 1.000 | 0 | .000 | 2 | 19 | 10 | .526 | 42 | 23 | 10 | 53.9 | .639 |
| Jhoan Duran | Sea | cl | 26 | 7 | 5 | .714 | 2 | .286 | 8 | 17 | 2 | .118 | 46 | 46 | 21 | 20.4 | .655 |
| Jake Eder* | Tex | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 1 | 0 | .000 | 17 | 7 | 5 | 64.4 | .583 |
| Scott Effross | Det | mr | 30 | 3 | 3 | 1.000 | 0 | .000 | 6 | 5 | 1 | .200 | 20 | 20 | 9 | 19.9 | .636 |
| Zach Eflin | | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 92.9 | .684 |
| Brandon Eisert* | Det | mr | 26 | 2 | 1 | .500 | 1 | .500 | 1 | 6 | 1 | .167 | 21 | 10 | 4 | 57.7 | .636 |
| Bryce Elder | | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 96.6 | .622 |
| Fraser Ellard* | Sea | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 2 | 2 | 0 | 32.0 | .531 |
| Nic Enright | | mr | 27 | 4 | 1 | .250 | 3 | .750 | 2 | 13 | 4 | .308 | 15 | 15 | 6 | 25.1 | .668 |
| Nathan Eovaldi | Oak | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 96.3 | .640 |
| Lucas Erceg | LAN | mr | 29 | 3 | 2 | .667 | 1 | .333 | 6 | 6 | 4 | .667 | 23 | 23 | 7 | 20.7 | .537 |
| Joey Estes | Mia | sp | 22 | 2 | 1 | .500 | 1 | .500 | 0 | 3 | 1 | .333 | 13 | 9 | 3 | 47.2 | .624 |
| Carlos Estevez | Tor | mr | 31 | 19 | 15 | .789 | 3 | .158 | 8 | 30 | 10 | .333 | 56 | 56 | 25 | 19.4 | .597 |
| Jeremiah Estrada | Sea | mr | 25 | 8 | 5 | .625 | 2 | .250 | 8 | 29 | 13 | .448 | 43 | 43 | 16 | 25.1 | .586 |
| Alex Faedo | Phi | sp | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 1 | .250 | 30 | 7 | 4 | 78.4 | .633 |
| Pete Fairbanks | ChN | cl | 30 | 4 | 1 | .250 | 3 | .750 | 7 | 16 | 8 | .500 | 28 | 28 | 8 | 19.0 | .592 |
| Bailey Falter* | KC | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 90.2 | .658 |
| Calvin Faucher | Hou | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 2 | 12 | 7 | .583 | 16 | 16 | 7 | 20.3 | .578 |
| Erick Fedde | Hou | sp | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 7 | 4 | .571 | 16 | 11 | 6 | 45.9 | .654 |
| Caleb Ferguson* | Tor | mr | 27 | 5 | 2 | .400 | 3 | .600 | 4 | 20 | 14 | .700 | 36 | 36 | 15 | 18.4 | .630 |
| Ryan Fernandez | SD | mr | 26 | 7 | 6 | .857 | 1 | .143 | 6 | 22 | 2 | .091 | 37 | 37 | 14 | 23.2 | .631 |
| Jose A. Ferrer* | Mia | mr | 24 | 0 | 0 | .000 | 0 | .000 | 3 | 8 | 4 | .500 | 7 | 7 | 0 | 24.6 | .605 |
| David Festa | | sp | 24 | 3 | 2 | .667 | 1 | .333 | 0 | 8 | 2 | .250 | 38 | 18 | 4 | 54.0 | .611 |
| J.P. Feyereisen | Pit | mr | 31 | 7 | 2 | .286 | 5 | .714 | 5 | 28 | 14 | .500 | 32 | 31 | 10 | 21.4 | .620 |
| Kyle Finnegan | NYN | cl | 32 | 8 | 4 | .500 | 4 | .500 | 6 | 30 | 8 | .267 | 46 | 46 | 21 | 21.3 | .645 |
| Richard Fitts | | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 96.4 | .659 |
| Jack Flaherty | Hou | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 1 | 0 | 98.8 | .608 |
| Josh Fleming* | Tam | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 0 | 5 | 0 | .000 | 6 | 6 | 4 | 16.3 | .684 |
| Wilmer Flores | ChN | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 77.0 | .649 |
| Dylan Floro | Was | mr | 33 | 5 | 3 | .600 | 2 | .400 | 0 | 15 | 5 | .333 | 25 | 25 | 19 | 20.8 | .685 |
| Mason Fluharty* | Phi | mr | 22 | 5 | 0 | .000 | 5 | 1.000 | 15 | 51 | 24 | .471 | 75 | 73 | 23 | 26.1 | .626 |
| Jason Foley | Oak | mr | 28 | 11 | 7 | .636 | 4 | .364 | 3 | 23 | 7 | .304 | 35 | 35 | 18 | 19.7 | .661 |
| J.P. France | KC | sp | 29 | 0 | 0 | .000 | 0 | .000 | 3 | 20 | 9 | .450 | 35 | 35 | 8 | 21.7 | .631 |
| Bowden Francis | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 8 | 1 | 0 | 72.6 | .640 |
| Kyle Freeland* | Min | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 3 | 3 | 21.0 | .714 |
| Luis Frias | Bal | mr | 26 | 2 | 1 | .500 | 0 | .000 | 1 | 4 | 0 | .000 | 24 | 4 | 1 | 85.7 | .602 |
| Max Fried* | Ari | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.6 | .663 |
| Kody Funderburk* | ChN | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 94.3 | .608 |
| Hunter Gaddis | Bos | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 15 | 6 | .400 | 41 | 17 | 5 | 63.6 | .616 |
| Giovanny Gallegos | | mr | 32 | 7 | 1 | .143 | 6 | .857 | 11 | 15 | 5 | .333 | 36 | 36 | 7 | 18.7 | .645 |
| Zac Gallen | | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 106.8 | .647 |
| Robert Garcia* | Was | mr | 28 | 3 | 0 | .000 | 3 | 1.000 | 0 | 12 | 4 | .333 | 18 | 18 | 13 | 32.5 | .602 |
| Yimi Garcia | | mr | 33 | 5 | 3 | .600 | 2 | .400 | 10 | 17 | 5 | .294 | 39 | 39 | 14 | 19.4 | .627 |
| Braxton Garrett* | Mia | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 92.6 | .660 |
| Reed Garrett | NYN | mr | 31 | 5 | 2 | .400 | 2 | .400 | 0 | 6 | 4 | .667 | 8 | 8 | 3 | 24.9 | .638 |
| Robert Gasser* | Atl | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 0 | 0 | 88.1 | .637 |
| Chris Gau | Oak | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 0 | .000 | 21 | 6 | 1 | 72.1 | .629 |
| Kevin Gausman | | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 37 | 0 | 0 | 101.3 | .659 |
| Domingo German | Pit | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 98.6 | .652 |
| Kyle Gibson | Min | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 100.8 | .618 |
| Luis Gil | | sp | 26 | 0 | 0 | .000 | 0 | .000 | 2 | 1 | 0 | .000 | 30 | 6 | 2 | 75.9 | .588 |
| Logan Gilbert | Ari | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 110.7 | .644 |
| Keagan Gillies | Cin | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 1 | .333 | 2 | 2 | 1 | 34.5 | .667 |
| Kevin Ginkel | | mr | 30 | 6 | 4 | .667 | 2 | .333 | 5 | 41 | 16 | .390 | 49 | 49 | 13 | 23.4 | .604 |
| J.T. Ginn | Pit | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 88.0 | .614 |
| Tyler Glasnow | Sea | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 86.1 | .652 |
| Woo-suk Go | Mil | mr | 25 | 2 | 1 | .500 | 1 | .500 | 1 | 23 | 8 | .348 | 35 | 35 | 17 | 19.7 | .606 |
| Yoendrys Gomez | NYA | sp | 24 | 3 | 2 | .667 | 1 | .333 | 4 | 9 | 3 | .333 | 22 | 22 | 9 | 15.3 | .595 |
| Marco Gonzales* | ChA | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 106.5 | .638 |
| Colton Gordon* | Phi | sp | 25 | 4 | 4 | 1.000 | 0 | .000 | 7 | 10 | 2 | .200 | 31 | 28 | 11 | 23.2 | .615 |
| MacKenzie Gore* | NYN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 101.3 | .621 |
| Anthony Gose* | Hou | mr | 33 | 5 | 3 | .600 | 2 | .400 | 12 | 37 | 10 | .270 | 60 | 60 | 14 | 19.1 | .570 |
| Gordon Graceffo | | sp | 24 | 2 | 1 | .500 | 1 | .500 | 7 | 12 | 1 | .083 | 44 | 38 | 10 | 29.6 | .624 |
| Brusdar Graterol | Bal | mr | 25 | 5 | 5 | 1.000 | 0 | .000 | 0 | 7 | 1 | .143 | 15 | 15 | 14 | 16.9 | .708 |
| Jon Gray | Oak | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 94.1 | .645 |
| Sonny Gray | | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 96.9 | .640 |
| Chad Green | ChN | mr | 33 | 8 | 5 | .625 | 3 | .375 | 18 | 9 | 0 | .000 | 49 | 49 | 15 | 18.9 | .657 |
| Hunter Greene | Col | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 25 | 2 | 2 | 97.4 | .615 |
| Michael Grove | | sp | 27 | 5 | 4 | .800 | 1 | .200 | 8 | 21 | 5 | .238 | 31 | 26 | 10 | 26.1 | .642 |
| Luis Guerrero | Tor | mr | 23 | 2 | 2 | 1.000 | 0 | .000 | 0 | 12 | 3 | .250 | 16 | 16 | 8 | 24.3 | .599 |
| Tyson Guerrero* | Sea | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 78.0 | .692 |
| Josh Hader* | | cl | 30 | 27 | 24 | .889 | 2 | .074 | 8 | 38 | 8 | .211 | 64 | 64 | 43 | 14.3 | .648 |
| Justin Hagenman | Oak | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 82.1 | .618 |
| DL Hall* | Bal | mr | 25 | 3 | 1 | .333 | 0 | .000 | 1 | 15 | 3 | .200 | 43 | 23 | 7 | 45.9 | .601 |
| Ian Hamilton | Tex | mr | 29 | 6 | 3 | .500 | 2 | .333 | 11 | 23 | 4 | .174 | 45 | 43 | 13 | 25.3 | .615 |
| Emerson Hancock | Sea | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 91.5 | .638 |
| Hayden Harris* | | mr | 25 | 4 | 3 | .750 | 0 | .000 | 6 | 21 | 8 | .381 | 30 | 30 | 14 | 19.5 | .614 |
| Kyle Harrison* | Atl | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 85.7 | .595 |
| Grant Hartwig | NYN | mr | 26 | 5 | 4 | .800 | 1 | .200 | 2 | 14 | 5 | .357 | 16 | 16 | 13 | 17.9 | .556 |
| Hunter Harvey | | mr | 29 | 14 | 11 | .786 | 3 | .214 | 8 | 28 | 8 | .286 | 49 | 49 | 30 | 15.3 | .675 |
| Andrew Heaney* | KC | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 18 | 2 | 1 | 86.6 | .634 |
| Ryan Helsley | | cl | 29 | 34 | 25 | .735 | 9 | .265 | 5 | 31 | 8 | .258 | 61 | 61 | 45 | 17.8 | .625 |
| Markevian Hence | SF | sp | 21 | 3 | 2 | .667 | 1 | .333 | 3 | 26 | 5 | .192 | 65 | 48 | 28 | 39.8 | .632 |
| Ryan Hennen* | Det | mr | 26 | 4 | 3 | .750 | 1 | .250 | 2 | 23 | 8 | .348 | 34 | 34 | 19 | 22.9 | .658 |
| Ronny Henriquez | Was | mr | 24 | 2 | 2 | 1.000 | 0 | .000 | 2 | 13 | 6 | .462 | 19 | 13 | 9 | 59.7 | .633 |
| Cole Henry | Pit | sp | 24 | 0 | 0 | .000 | 0 | .000 | 2 | 8 | 4 | .500 | 26 | 8 | 1 | 64.6 | .613 |
| Tommy Henry* | LAA | sp | 26 | 4 | 3 | .750 | 1 | .250 | 4 | 20 | 7 | .350 | 40 | 34 | 14 | 31.5 | .622 |
| Sam Hentges* | Tex | mr | 27 | 11 | 10 | .909 | 1 | .091 | 5 | 22 | 5 | .227 | 29 | 29 | 18 | 18.1 | .633 |
| Carlos Hernandez | Tex | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 | 40.0 | .600 |
| Daysbel Hernandez | NYN | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 2 | 2 | 2 | 22.0 | .568 |
| Jakob Hernandez* | Oak | mr | 28 | 2 | 1 | .500 | 1 | .500 | 1 | 2 | 1 | .500 | 6 | 6 | 2 | 16.7 | .560 |
| Jose Hernandez* | Was | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 3 | 18 | 10 | .556 | 20 | 19 | 7 | 22.5 | .592 |
| Tim Herrin* | Sea | mr | 27 | 5 | 2 | .400 | 3 | .600 | 2 | 39 | 13 | .333 | 51 | 51 | 18 | 26.4 | .606 |
| Jordan Hicks | SF | mr | 27 | 14 | 9 | .643 | 3 | .214 | 15 | 78 | 27 | .346 | 99 | 98 | 24 | 18.9 | .575 |
| Porter Hodge | Was | mr | 23 | 2 | 2 | 1.000 | 0 | .000 | 1 | 3 | 1 | .333 | 19 | 7 | 5 | 72.5 | .587 |
| Jeff Hoffman | | mr | 31 | 20 | 12 | .600 | 8 | .400 | 9 | 28 | 7 | .250 | 59 | 58 | 31 | 21.1 | .613 |
| Gunnar Hoglund | Oak | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 79.6 | .681 |
| Colin Holderman | Phi | mr | 28 | 17 | 12 | .706 | 5 | .294 | 6 | 47 | 14 | .298 | 73 | 73 | 38 | 19.6 | .616 |
| Grant Holman | KC | mr | 24 | 5 | 5 | 1.000 | 0 | .000 | 7 | 36 | 11 | .306 | 65 | 65 | 18 | 13.5 | .637 |
| Clay Holmes | Oak | cl | 31 | 7 | 2 | .286 | 5 | .714 | 19 | 19 | 2 | .105 | 62 | 62 | 6 | 19.1 | .637 |
| Grant Holmes | Mia | mr | 28 | 5 | 4 | .800 | 1 | .200 | 10 | 15 | 3 | .200 | 31 | 29 | 10 | 24.5 | .641 |
| Tyler Holton* | | mr | 28 | 17 | 13 | .765 | 4 | .235 | 2 | 29 | 5 | .172 | 66 | 63 | 46 | 20.8 | .666 |
| Brent Honeywell | Col | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 1 | 7 | 4 | .571 | 13 | 8 | 5 | 56.5 | .635 |
| Tanner Houck | LAN | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 94.2 | .612 |
| Spencer Howard | | sp | 27 | 1 | 0 | .000 | 1 | 1.000 | 3 | 13 | 6 | .462 | 21 | 19 | 5 | 27.2 | .608 |
| Bryan Hudson* | Col | mr | 27 | 9 | 2 | .222 | 7 | .778 | 10 | 20 | 8 | .400 | 45 | 45 | 14 | 19.9 | .616 |
| Daniel Hudson | | mr | 37 | 3 | 1 | .333 | 0 | .000 | 1 | 10 | 5 | .500 | 25 | 20 | 6 | 30.2 | .618 |
| Brandon Hughes* | NYN | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 1 | 12 | 4 | .333 | 16 | 16 | 11 | 19.0 | .595 |
| Kyle Hurt | Bos | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 2 | 2 | 77.6 | .615 |
| Brant Hurter* | ChN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 86.4 | .644 |
| Raisel Iglesias | | cl | 34 | 32 | 25 | .781 | 7 | .219 | 6 | 29 | 8 | .276 | 60 | 60 | 46 | 17.0 | .686 |
| Shota Imanaga* | SD | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 82.4 | .640 |
| Jairo Iriarte | Col | sp | 22 | 2 | 0 | .000 | 2 | 1.000 | 3 | 10 | 3 | .300 | 26 | 23 | 10 | 29.3 | .580 |
| Cole Irvin* | ChA | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 33 | 1 | 0 | 89.6 | .668 |
| Jake Irvin | | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 88.9 | .602 |
| Jay Jackson | Mia | mr | 36 | 15 | 9 | .600 | 6 | .400 | 8 | 28 | 9 | .321 | 48 | 48 | 25 | 18.2 | .637 |
| Alek Jacob | Pit | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 12 | 3 | .250 | 11 | 11 | 4 | 24.9 | .613 |
| Kenley Jansen | | cl | 36 | 17 | 11 | .647 | 6 | .353 | 9 | 24 | 4 | .167 | 52 | 52 | 29 | 19.1 | .604 |
| Bryce Jarvis | LAA | sp | 26 | 2 | 2 | 1.000 | 0 | .000 | 2 | 19 | 8 | .421 | 30 | 25 | 10 | 32.6 | .605 |
| Cristian Javier | Min | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 104.0 | .607 |
| Griffin Jax | Min | mr | 29 | 12 | 10 | .833 | 2 | .167 | 1 | 18 | 2 | .111 | 34 | 31 | 22 | 23.6 | .641 |
| Joe Jimenez | NYN | mr | 29 | 5 | 1 | .200 | 4 | .800 | 25 | 15 | 2 | .133 | 64 | 64 | 11 | 17.7 | .617 |
| Jackson Jobe | SF | sp | 21 | 1 | 0 | .000 | 1 | 1.000 | 0 | 24 | 10 | .417 | 43 | 28 | 23 | 45.2 | .615 |
| Pierce Johnson | Mil | mr | 33 | 4 | 4 | 1.000 | 0 | .000 | 6 | 19 | 4 | .211 | 31 | 31 | 9 | 18.1 | .607 |
| Seth Johnson | Phi | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 14 | 0 | .000 | 27 | 13 | 4 | 55.8 | .611 |
| Jared Jones | Bos | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 101.0 | .606 |
| Hayden Juenger | Hou | mr | 23 | 1 | 1 | 1.000 | 0 | .000 | 2 | 12 | 2 | .167 | 36 | 30 | 14 | 32.3 | .593 |
| Jakob Junis | Det | mr | 31 | 4 | 2 | .500 | 2 | .500 | 0 | 3 | 1 | .333 | 9 | 7 | 6 | 36.3 | .670 |
| Tommy Kahnle | Oak | mr | 34 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 3 | .429 | 17 | 17 | 8 | 16.0 | .643 |
| Mitch Keller | | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 98.8 | .647 |
| Antoine Kelly* | Atl | mr | 24 | 3 | 3 | 1.000 | 0 | .000 | 0 | 14 | 4 | .286 | 13 | 13 | 8 | 18.2 | .593 |
| Joe Kelly | LAA | mr | 36 | 1 | 1 | 1.000 | 0 | .000 | 3 | 16 | 6 | .375 | 20 | 20 | 10 | 16.9 | .617 |
| Kevin Kelly | | mr | 26 | 16 | 11 | .688 | 4 | .250 | 15 | 36 | 13 | .361 | 62 | 62 | 33 | 17.9 | .668 |
| Merrill Kelly | Det | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 106.7 | .663 |
| Michael Kelly | Bal | mr | 31 | 5 | 2 | .400 | 3 | .600 | 5 | 22 | 7 | .318 | 28 | 28 | 11 | 23.4 | .567 |
| Zack Kelly | Bal | mr | 29 | 2 | 1 | .500 | 1 | .500 | 4 | 22 | 11 | .500 | 22 | 22 | 6 | 27.4 | .533 |
| Orion Kerkering | Bos | mr | 23 | 17 | 10 | .588 | 6 | .353 | 14 | 36 | 14 | .389 | 61 | 61 | 22 | 20.2 | .657 |
| Ray Kerr* | LAA | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 2 | 4 | 2 | .500 | 8 | 8 | 4 | 15.8 | .603 |
| Brett Kerry | NYA | sp | 25 | 3 | 1 | .333 | 2 | .667 | 2 | 8 | 4 | .500 | 24 | 11 | 4 | 62.1 | .611 |
| Clayton Kershaw* | LAA | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 100.7 | .690 |
| Yusei Kikuchi* | NYN | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 97.9 | .647 |
| Craig Kimbrel | | cl | 36 | 12 | 9 | .750 | 3 | .250 | 5 | 25 | 9 | .360 | 47 | 47 | 24 | 18.9 | .598 |
| John King* | StL | mr | 29 | 10 | 7 | .700 | 3 | .300 | 9 | 27 | 10 | .370 | 48 | 48 | 23 | 17.9 | .683 |
| Michael King | Tam | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 93.1 | .626 |
| George Kirby | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 91.4 | .694 |
| Andrew Kittredge | ChN | mr | 34 | 2 | 2 | 1.000 | 0 | .000 | 0 | 5 | 1 | .200 | 12 | 12 | 5 | 19.3 | .662 |
| Will Klein | Mia | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 1 | 5 | 2 | .400 | 6 | 6 | 4 | 31.3 | .580 |
| Jared Koenig* | Tam | mr | 30 | 0 | 0 | .000 | 0 | .000 | 2 | 6 | 1 | .167 | 9 | 9 | 3 | 18.8 | .609 |
| Michael Kopech | SF | sp | 28 | 1 | 1 | 1.000 | 0 | .000 | 0 | 5 | 2 | .400 | 20 | 6 | 3 | 79.3 | .573 |
| Dean Kremer | Det | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 101.8 | .639 |
| Alex Lange | LAN | cl | 28 | 32 | 23 | .719 | 9 | .281 | 0 | 27 | 6 | .222 | 48 | 48 | 41 | 20.7 | .610 |
| Jake Latz* | Phi | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 0 | .000 | 9 | 9 | 5 | 14.3 | .682 |
| Nate Lavender* | ChA | mr | 24 | 3 | 2 | .667 | 1 | .333 | 11 | 34 | 9 | .265 | 59 | 59 | 16 | 21.8 | .611 |
| Justin Lawrence | Bos | mr | 29 | 27 | 22 | .815 | 5 | .185 | 2 | 31 | 4 | .129 | 53 | 53 | 46 | 20.7 | .596 |
| Max Lazar | NYA | mr | 25 | 9 | 2 | .222 | 7 | .778 | 3 | 49 | 25 | .510 | 75 | 75 | 25 | 22.8 | .668 |
| Jose Leclerc | Pit | mr | 30 | 2 | 2 | 1.000 | 0 | .000 | 11 | 43 | 12 | .279 | 55 | 55 | 14 | 20.3 | .594 |
| Dylan Lee* | | mr | 29 | 10 | 6 | .600 | 4 | .400 | 24 | 29 | 11 | .379 | 63 | 63 | 16 | 17.3 | .641 |
| Jack Leiter | SF | sp | 24 | 6 | 3 | .500 | 3 | .500 | 1 | 26 | 9 | .346 | 38 | 25 | 18 | 52.6 | .594 |
| Mark Leiter | Bos | mr | 33 | 7 | 6 | .857 | 1 | .143 | 4 | 23 | 7 | .304 | 50 | 48 | 23 | 24.2 | .616 |
| Matthew Liberatore* | | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 2 | 1 | 0 | .000 | 22 | 4 | 2 | 87.5 | .623 |
| Yu-Min Lin* | Bal | sp | 20 | 5 | 3 | .600 | 2 | .400 | 3 | 10 | 2 | .200 | 55 | 26 | 12 | 59.2 | .607 |
| Zack Littell | Cle | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 4 | 5 | 4 | .800 | 32 | 9 | 1 | 75.4 | .666 |
| Brendon Little* | LAN | mr | 27 | 11 | 4 | .364 | 6 | .545 | 12 | 36 | 17 | .472 | 62 | 62 | 26 | 21.0 | .602 |
| Luke Little* | Hou | mr | 23 | 5 | 1 | .200 | 3 | .600 | 4 | 16 | 3 | .188 | 29 | 29 | 8 | 19.0 | .583 |
| Ben Lively | | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 97.8 | .635 |
| Mauricio Llovera | StL | mr | 28 | 4 | 3 | .750 | 1 | .250 | 1 | 4 | 1 | .250 | 16 | 10 | 6 | 39.1 | .662 |
| Jonathan Loaisiga | Ari | mr | 29 | 0 | 0 | .000 | 0 | .000 | 3 | 1 | 1 | 1.000 | 8 | 8 | 1 | 18.0 | .715 |
| Nick Lodolo* | | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 91.2 | .660 |
| Pablo Lopez | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 1 | 1 | 104.2 | .662 |
| Reynaldo Lopez | LAA | mr | 30 | 5 | 2 | .400 | 3 | .600 | 9 | 9 | 4 | .444 | 32 | 31 | 9 | 23.1 | .625 |
| Michael Lorenzen | LAA | sp | 32 | 1 | 1 | 1.000 | 0 | .000 | 1 | 11 | 1 | .091 | 25 | 13 | 8 | 54.7 | .642 |
| Ryan Loutos | Mia | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 1 | 18.0 | .611 |
| Richard Lovelady* | | mr | 28 | 4 | 2 | .500 | 2 | .500 | 7 | 16 | 3 | .188 | 29 | 29 | 7 | 14.3 | .637 |
| Seth Lugo | NYN | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 97.3 | .661 |
| Jesus Luzardo* | Cle | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 99.7 | .634 |
| Daniel Lynch* | Phi | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 103.0 | .573 |
| Lance Lynn | LAN | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 99.0 | .647 |
| Adam Macko* | | sp | 23 | 0 | 0 | .000 | 0 | .000 | 2 | 17 | 2 | .118 | 30 | 25 | 7 | 37.2 | .573 |
| Kenta Maeda | Mil | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 91.0 | .659 |
| Tyler Mahle | Ari | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 107.5 | .614 |
| Anthony Maldonado | Tor | mr | 26 | 11 | 5 | .455 | 5 | .455 | 8 | 41 | 15 | .366 | 74 | 74 | 33 | 21.0 | .638 |
| Matt Manning | Mia | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 18 | 4 | 1 | 78.8 | .626 |
| Alek Manoah | Sea | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 92.8 | .631 |
| Joe Mantiply* | KC | mr | 33 | 4 | 2 | .500 | 2 | .500 | 12 | 44 | 8 | .182 | 59 | 59 | 16 | 13.9 | .649 |
| Ron Marinaccio | ChA | mr | 28 | 9 | 6 | .667 | 3 | .333 | 8 | 50 | 16 | .320 | 80 | 80 | 17 | 18.0 | .586 |
| German Marquez | Bos | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 123.0 | .646 |
| Alec Marsh | | sp | 26 | 4 | 3 | .750 | 1 | .250 | 1 | 15 | 6 | .400 | 41 | 32 | 14 | 40.1 | .619 |
| Chris Martin | ChN | mr | 38 | 3 | 3 | 1.000 | 0 | .000 | 2 | 20 | 7 | .350 | 24 | 24 | 10 | 18.7 | .699 |
| Davis Martin | SD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 93.0 | .602 |
| Justin Martinez | Tex | mr | 22 | 5 | 3 | .600 | 2 | .400 | 4 | 29 | 10 | .345 | 54 | 54 | 20 | 19.1 | .542 |
| Nick Martinez | Mil | mr | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 98.0 | .643 |
| Seth Martinez | Hou | mr | 29 | 9 | 5 | .556 | 4 | .444 | 14 | 51 | 19 | .373 | 85 | 85 | 23 | 20.9 | .633 |
| Phil Maton | | mr | 31 | 11 | 6 | .545 | 5 | .455 | 14 | 22 | 5 | .227 | 58 | 58 | 16 | 19.4 | .610 |
| Yuki Matsui* | NYN | mr | 28 | 12 | 11 | .917 | 1 | .083 | 7 | 26 | 9 | .346 | 46 | 46 | 22 | 21.1 | .592 |
| Steven Matz* | | sp | 33 | 1 | 1 | 1.000 | 0 | .000 | 1 | 4 | 1 | .250 | 15 | 9 | 2 | 48.9 | .631 |
| Tyler Matzek* | SD | mr | 33 | 1 | 1 | 1.000 | 0 | .000 | 7 | 11 | 5 | .455 | 17 | 17 | 5 | 16.4 | .602 |
| Tim Mayza* | | mr | 32 | 2 | 0 | .000 | 1 | .500 | 3 | 10 | 4 | .400 | 20 | 20 | 5 | 14.6 | .649 |
| James McArthur | Det | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 4 | 0 | .000 | 7 | 7 | 2 | 20.4 | .650 |
| Chayce McDermott | LAN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 89.1 | .594 |
| Griff McGarry | Bal | sp | 25 | 6 | 3 | .500 | 3 | .500 | 8 | 35 | 8 | .229 | 50 | 50 | 10 | 21.6 | .550 |
| Scott McGough | Hou | mr | 34 | 10 | 6 | .600 | 4 | .400 | 0 | 21 | 10 | .476 | 26 | 26 | 22 | 16.5 | .626 |
| Michael McGreevy | ChA | sp | 23 | 5 | 5 | 1.000 | 0 | .000 | 0 | 9 | 1 | .111 | 14 | 12 | 12 | 25.6 | .680 |
| Evan McKendry | SD | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 2 | .250 | 16 | 6 | 1 | 70.0 | .660 |
| Triston McKenzie | | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 96.6 | .642 |
| John McMillon | Pit | mr | 26 | 2 | 1 | .500 | 1 | .500 | 0 | 4 | 0 | .000 | 9 | 9 | 4 | 31.8 | .535 |
| John Means* | Tex | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 93.5 | .658 |
| Nick Mears | | mr | 27 | 0 | 0 | .000 | 0 | .000 | 2 | 1 | 0 | .000 | 6 | 6 | 0 | 23.5 | .496 |
| Trevor Megill | | mr | 30 | 5 | 4 | .800 | 1 | .200 | 7 | 14 | 4 | .286 | 35 | 35 | 15 | 18.9 | .623 |
| Tylor Megill | NYN | sp | 28 | 1 | 1 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 3 | 3 | 3 | 27.3 | .707 |
| Juan M. Mejia | Mia | mr | 23 | 2 | 1 | .500 | 1 | .500 | 1 | 5 | 1 | .200 | 7 | 7 | 6 | 22.3 | .577 |
| Cristian Mena | Col | sp | 21 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 2 | 1.000 | 24 | 1 | 0 | 89.3 | .611 |
| Michael Mercado | NYA | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 12 | 3 | 2 | 77.3 | .604 |
| Julian Merryweather | | mr | 32 | 2 | 1 | .500 | 1 | .500 | 4 | 9 | 2 | .222 | 14 | 14 | 5 | 22.1 | .660 |
| Max Meyer | ChA | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 89.9 | .614 |
| Miles Mikolas | StL | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 96.8 | .675 |
| Bobby Miller | Bal | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 1 | 1 | 0 | .000 | 34 | 7 | 1 | 81.5 | .639 |
| Bryce Miller | | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 37 | 1 | 1 | 93.5 | .658 |
| Erik Miller* | | mr | 26 | 2 | 1 | .500 | 1 | .500 | 1 | 11 | 7 | .636 | 17 | 17 | 3 | 34.4 | .572 |
| Mason Miller | Bos | mr | 25 | 10 | 6 | .600 | 4 | .400 | 18 | 20 | 3 | .150 | 61 | 61 | 21 | 21.2 | .616 |
| Tyson Miller | | mr | 28 | 3 | 2 | .667 | 1 | .333 | 9 | 14 | 7 | .500 | 27 | 27 | 8 | 19.4 | .632 |
| Hoby Milner* | Cin | mr | 33 | 3 | 1 | .333 | 2 | .667 | 17 | 16 | 9 | .563 | 44 | 44 | 6 | 15.4 | .646 |
| A.J. Minter* | Was | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 2 | 18 | 4 | .222 | 25 | 25 | 7 | 16.5 | .671 |
| Andrew Misiaszek* | Cin | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 7 | 7 | 2 | 17.0 | .580 |
| Jacob Misiorowski | Tex | sp | 22 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 6 | .857 | 20 | 13 | 5 | 57.0 | .546 |
| Casey Mize | | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 100.3 | .650 |
| Sam Moll* | Tor | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 2 | 10 | 1 | .100 | 16 | 16 | 3 | 14.8 | .650 |
| Frankie Montas | ChN | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 94.1 | .640 |
| Keider Montero | | sp | 23 | 2 | 0 | .000 | 2 | 1.000 | 1 | 9 | 4 | .444 | 11 | 11 | 3 | 22.8 | .665 |
| Jordan Montgomery* | | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 100.4 | .650 |
| Matt Moore* | Min | mr | 35 | 6 | 3 | .500 | 3 | .500 | 15 | 37 | 13 | .351 | 59 | 59 | 13 | 19.1 | .630 |
| Francisco Morales | LAN | mr | 24 | 1 | 0 | .000 | 1 | 1.000 | 2 | 22 | 9 | .409 | 44 | 44 | 10 | 20.8 | .575 |
| Adrian Morejon* | | mr | 25 | 3 | 0 | .000 | 3 | 1.000 | 9 | 25 | 12 | .480 | 45 | 45 | 10 | 15.8 | .646 |
| Eli Morgan | Det | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 91.0 | .654 |
| Charlie Morton | SD | sp | 40 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 109.0 | .605 |
| Kyle Muller* | Tor | sp | 26 | 5 | 1 | .200 | 3 | .600 | 9 | 15 | 6 | .400 | 26 | 26 | 7 | 18.8 | .605 |
| Andres Munoz | Sea | mr | 25 | 4 | 1 | .250 | 3 | .750 | 22 | 19 | 6 | .316 | 67 | 67 | 12 | 18.8 | .615 |
| Roddery Munoz | Tex | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 1 | 4 | 3 | .750 | 3 | 3 | 1 | 19.7 | .542 |
| Ryan Murphy | SF | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 2 | 2 | 81.0 | .620 |
| Joe Musgrove | | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 106.6 | .647 |
| Tobias Myers | | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 7 | 3 | .429 | 10 | 10 | 7 | 20.6 | .621 |
| Andrew Nardi* | Atl | mr | 25 | 7 | 5 | .714 | 2 | .286 | 14 | 28 | 8 | .286 | 53 | 53 | 17 | 20.2 | .610 |
| Nick Nastrini | SD | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 83.0 | .663 |
| Packy Naughton* | Was | sp | 28 | 2 | 2 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 17 | 6 | 4 | 68.6 | .641 |
| Jack Neely | | mr | 24 | 15 | 9 | .600 | 6 | .400 | 6 | 42 | 15 | .357 | 72 | 72 | 34 | 22.8 | .594 |
| Kyle Nelson* | Atl | mr | 27 | 2 | 2 | 1.000 | 0 | .000 | 4 | 6 | 1 | .167 | 8 | 8 | 2 | 14.1 | .646 |
| Ryne Nelson | Cin | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 2 | 2 | 84.6 | .653 |
| Hector Neris | Cin | mr | 35 | 5 | 3 | .600 | 2 | .400 | 17 | 15 | 2 | .133 | 58 | 58 | 15 | 17.9 | .624 |
| Kyle Nicolas | Atl | sp | 25 | 3 | 0 | .000 | 3 | 1.000 | 5 | 37 | 15 | .405 | 46 | 46 | 15 | 21.6 | .577 |
| Aaron Nola | Cle | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 105.3 | .673 |
| Dedniel Nunez | Tex | mr | 28 | 5 | 2 | .400 | 3 | .600 | 14 | 44 | 16 | .364 | 66 | 66 | 20 | 22.7 | .602 |
| Bailey Ober | | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 85.8 | .664 |
| Pierson Ohl | KC | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 92.9 | .702 |
| Shohei Ohtani | Tex | dh | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 97.7 | .659 |
| Steven Okert* | KC | mr | 32 | 9 | 4 | .444 | 4 | .444 | 10 | 37 | 11 | .297 | 62 | 62 | 16 | 16.2 | .630 |
| Mat Olsen | NYN | mr | 23 | 8 | 7 | .875 | 1 | .125 | 4 | 57 | 8 | .140 | 70 | 70 | 29 | 22.4 | .623 |
| Reese Olson | | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 8 | 3 | .375 | 23 | 8 | 3 | 65.3 | .613 |
| Kaleb Ort | Hou | mr | 32 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 2 | .333 | 8 | 8 | 2 | 13.4 | .589 |
| Luis L. Ortiz | | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 17 | 12 | .706 | 37 | 32 | 13 | 30.9 | .584 |
| Michel Otanez | Tex | mr | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 2 | 1.000 | 6 | 6 | 2 | 16.2 | .515 |
| Adam Ottavino | SD | mr | 38 | 4 | 2 | .500 | 2 | .500 | 6 | 18 | 7 | .389 | 39 | 39 | 17 | 21.4 | .586 |
| Chris Paddack | | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 87.5 | .666 |
| Emilio Pagan | ChA | mr | 33 | 5 | 3 | .600 | 2 | .400 | 3 | 30 | 9 | .300 | 39 | 39 | 16 | 15.3 | .628 |
| Daniel Palencia | Mia | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 1 | 0 | 25.0 | .600 |
| Andre Pallante | Min | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 2 | 35 | 17 | .486 | 60 | 55 | 26 | 26.1 | .644 |
| Carson Palmquist* | Ari | sp | 23 | 1 | 0 | .000 | 1 | 1.000 | 1 | 4 | 0 | .000 | 24 | 23 | 15 | 29.6 | .610 |
| Enoli Paredes | NYA | mr | 28 | 7 | 3 | .429 | 3 | .429 | 8 | 25 | 7 | .280 | 47 | 47 | 9 | 19.8 | .569 |
| Mitchell Parker* | Atl | sp | 24 | 2 | 2 | 1.000 | 0 | .000 | 3 | 17 | 2 | .118 | 38 | 14 | 7 | 62.0 | .611 |
| Joel Payamps | Cin | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 5 | 27 | 4 | .148 | 32 | 32 | 7 | 22.7 | .609 |
| Nate Pearson | | mr | 27 | 6 | 2 | .333 | 4 | .667 | 16 | 42 | 13 | .310 | 62 | 62 | 18 | 23.3 | .593 |
| Elvis Peguero | | mr | 27 | 4 | 1 | .250 | 3 | .750 | 5 | 26 | 11 | .423 | 44 | 44 | 14 | 21.4 | .641 |
| Walter Pennington* | | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 9 | 9 | 5 | 26.1 | .604 |
| Ryan Pepiot | | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 3 | 0 | .000 | 35 | 5 | 4 | 77.4 | .606 |
| Freddy Peralta | | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 100.6 | .622 |
| Wandy Peralta* | SD | mr | 32 | 2 | 2 | 1.000 | 0 | .000 | 11 | 18 | 3 | .167 | 28 | 28 | 10 | 17.6 | .579 |
| Cionel Perez* | Mil | mr | 28 | 1 | 1 | 1.000 | 0 | .000 | 0 | 5 | 1 | .200 | 6 | 6 | 5 | 10.8 | .538 |
| Martin Perez* | LAN | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 97.9 | .659 |
| Jack Perkins | Bal | sp | 26 | 2 | 1 | .500 | 1 | .500 | 1 | 7 | 3 | .429 | 9 | 8 | 3 | 32.8 | .580 |
| David Peterson* | Oak | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 93.5 | .620 |
| Brandon Pfaadt | Col | sp | 25 | 1 | 1 | 1.000 | 0 | .000 | 1 | 0 | 0 | .000 | 39 | 8 | 2 | 83.9 | .652 |
| Evan Phillips | Mil | cl | 29 | 27 | 20 | .741 | 7 | .259 | 4 | 23 | 8 | .348 | 45 | 45 | 34 | 18.8 | .647 |
| Nick Pivetta | Was | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 97.1 | .632 |
| Colin Poche* | Col | mr | 30 | 6 | 4 | .667 | 2 | .333 | 4 | 34 | 9 | .265 | 41 | 41 | 25 | 17.4 | .603 |
| Cade Povich* | Bos | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 97.4 | .613 |
| Ryan Pressly | Cin | cl | 35 | 36 | 33 | .917 | 3 | .083 | 4 | 40 | 10 | .250 | 64 | 64 | 57 | 15.9 | .656 |
| A.J. Puk* | LAN | mr | 29 | 0 | 0 | .000 | 0 | .000 | 2 | 4 | 0 | .000 | 10 | 10 | 3 | 14.2 | .683 |
| Jose Quijada* | Mia | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 2 | 4 | 0 | .000 | 8 | 8 | 4 | 18.9 | .583 |
| Jose Quintana* | Pit | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 96.4 | .639 |
| Cole Ragans* | Was | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 101.4 | .662 |
| Taylor Rashi | ChN | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 1 | 1 | 82.6 | .601 |
| Drew Rasmussen | Bos | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 97.9 | .617 |
| Robbie Ray* | StL | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 96.8 | .654 |
| Marco Raya | Mia | sp | 21 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 19 | 8 | 7 | 62.6 | .619 |
| Colin Rea | Mil | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 1 | 1 | 83.8 | .670 |
| Sean Reid-Foley | | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 4 | .667 | 9 | 9 | 2 | 22.2 | .550 |
| Sean Reynolds | Mia | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 0 | 0 | .000 | 3 | 3 | 1 | 32.7 | .541 |
| Trevor Richards | NYN | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 91.8 | .615 |
| Sem Robberse | Pit | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 92.8 | .630 |
| Ethan Roberts | Oak | mr | 26 | 2 | 1 | .500 | 1 | .500 | 2 | 27 | 5 | .185 | 37 | 34 | 13 | 24.9 | .646 |
| David Robertson | | cl | 39 | 14 | 9 | .643 | 5 | .357 | 2 | 18 | 9 | .500 | 26 | 26 | 18 | 18.7 | .589 |
| Nick Robertson | Cin | mr | 25 | 3 | 3 | 1.000 | 0 | .000 | 5 | 26 | 8 | .308 | 36 | 36 | 16 | 19.9 | .642 |
| Joe Rock* | Cle | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 1 | 1 | 97.2 | .632 |
| Carlos Rodon* | ChA | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 101.9 | .626 |
| Carlos F. Rodriguez | Tor | sp | 22 | 1 | 0 | .000 | 1 | 1.000 | 3 | 13 | 3 | .231 | 25 | 23 | 5 | 27.6 | .634 |
| Eduardo Rodriguez* | Min | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 83.8 | .631 |
| Grayson Rodriguez | Tex | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 100.2 | .641 |
| Manuel Rodriguez | Pit | mr | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 6 | 6 | 3 | 24.2 | .600 |
| Randy Rodriguez | Hou | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 4 | 4 | 3 | 16.8 | .597 |
| Yariel Rodriguez | ChN | mr | 27 | 2 | 2 | 1.000 | 0 | .000 | 8 | 22 | 7 | .318 | 32 | 31 | 11 | 21.4 | .627 |
| Yerry Rodriguez | LAN | mr | 26 | 3 | 0 | .000 | 2 | .667 | 7 | 27 | 6 | .222 | 43 | 43 | 12 | 16.0 | .610 |
| Taylor Rogers* | Ari | mr | 33 | 5 | 4 | .800 | 1 | .200 | 9 | 31 | 8 | .258 | 50 | 50 | 23 | 15.0 | .664 |
| Trevor Rogers* | SF | sp | 26 | 3 | 3 | 1.000 | 0 | .000 | 0 | 23 | 12 | .522 | 28 | 14 | 13 | 62.8 | .653 |
| Tyler Rogers | StL | mr | 33 | 8 | 3 | .375 | 4 | .500 | 12 | 29 | 6 | .207 | 62 | 62 | 21 | 17.3 | .682 |
| Jordan Romano | Cle | cl | 31 | 7 | 6 | .857 | 1 | .143 | 0 | 17 | 6 | .353 | 19 | 19 | 15 | 18.6 | .635 |
| JoJo Romero* | | mr | 27 | 19 | 12 | .632 | 7 | .368 | 14 | 34 | 6 | .176 | 56 | 55 | 25 | 18.5 | .656 |
| Landen Roupp | | sp | 25 | 1 | 0 | .000 | 1 | 1.000 | 3 | 14 | 8 | .571 | 39 | 23 | 8 | 51.0 | .613 |
| Jackson Rutledge | SF | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 114.7 | .635 |
| Joe Ryan | Mia | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 100.4 | .649 |
| Andrew Saalfrank* | Mia | mr | 26 | 4 | 2 | .500 | 0 | .000 | 6 | 14 | 3 | .214 | 30 | 30 | 7 | 21.1 | .602 |
| Chris Sale* | LAA | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 87.3 | .654 |
| Cristopher Sanchez* | Tam | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 92.0 | .666 |
| Nick Sandlin | Atl | mr | 27 | 8 | 2 | .250 | 6 | .750 | 22 | 30 | 12 | .400 | 69 | 69 | 20 | 19.7 | .606 |
| Patrick Sandoval* | | sp | 27 | 6 | 3 | .500 | 2 | .333 | 6 | 21 | 10 | .476 | 32 | 30 | 10 | 22.6 | .627 |
| Cole Sands | | mr | 26 | 8 | 4 | .500 | 4 | .500 | 15 | 34 | 12 | .353 | 67 | 67 | 24 | 17.0 | .628 |
| Tony Santillan | Col | mr | 27 | 2 | 1 | .500 | 1 | .500 | 1 | 20 | 11 | .550 | 27 | 22 | 12 | 33.1 | .553 |
| Gregory Santos | LAA | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 8 | 9 | 4 | .444 | 15 | 15 | 1 | 16.6 | .631 |
| Tayler Saucedo* | Mil | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 4 | 17 | 5 | .294 | 22 | 22 | 10 | 18.3 | .638 |
| Josh Sborz | SD | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 4 | 8 | 3 | .375 | 16 | 16 | 3 | 19.9 | .626 |
| Max Scherzer | | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 97.8 | .654 |
| Clarke Schmidt | Col | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 96.4 | .598 |
| John Schreiber | ChA | mr | 30 | 3 | 3 | 1.000 | 0 | .000 | 1 | 34 | 14 | .412 | 47 | 47 | 17 | 22.3 | .623 |
| Christian Scott | | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 90.2 | .637 |
| Tanner Scott* | NYN | mr | 29 | 12 | 7 | .583 | 4 | .333 | 10 | 20 | 6 | .300 | 50 | 50 | 20 | 21.9 | .627 |
| Tayler Scott | Phi | mr | 32 | 2 | 1 | .500 | 1 | .500 | 2 | 20 | 9 | .450 | 22 | 19 | 3 | 32.6 | .572 |
| JP Sears* | Cin | sp | 28 | 0 | 0 | .000 | 0 | .000 | 4 | 9 | 1 | .111 | 24 | 12 | 3 | 56.1 | .620 |
| Luis Severino | Tex | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 94.4 | .630 |
| Paul Sewald | LAA | cl | 34 | 7 | 5 | .714 | 2 | .286 | 10 | 17 | 6 | .353 | 40 | 40 | 20 | 19.6 | .616 |
| Ian Seymour* | Mia | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 78.5 | .659 |
| Davis Sharpe | Atl | mr | 24 | 8 | 5 | .625 | 3 | .375 | 22 | 49 | 18 | .367 | 88 | 88 | 22 | 21.4 | .657 |
| Chase Silseth | Sea | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 90.3 | .622 |
| Lucas Sims | Col | mr | 30 | 4 | 2 | .500 | 2 | .500 | 6 | 22 | 13 | .591 | 39 | 39 | 11 | 22.8 | .572 |
| Brady Singer | LAN | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 107.1 | .646 |
| Tarik Skubal* | Tam | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 94.6 | .657 |
| Cade Smith | Tam | mr | 25 | 5 | 2 | .400 | 3 | .600 | 8 | 26 | 11 | .423 | 53 | 53 | 25 | 21.2 | .593 |
| Drew Smith | NYN | mr | 30 | 3 | 2 | .667 | 1 | .333 | 1 | 7 | 4 | .571 | 16 | 16 | 9 | 20.4 | .627 |
| Will Smith* | ChN | cl | 34 | 6 | 2 | .333 | 3 | .500 | 24 | 33 | 12 | .364 | 57 | 57 | 17 | 17.8 | .607 |
| AJ Smith-Shawver | Tex | sp | 21 | 1 | 0 | .000 | 1 | 1.000 | 4 | 16 | 5 | .313 | 25 | 18 | 5 | 39.8 | .581 |
| Blake Snell* | Cin | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 100.8 | .599 |
| Robby Snelling* | Bal | sp | 20 | 5 | 3 | .600 | 1 | .200 | 9 | 20 | 7 | .350 | 58 | 30 | 8 | 55.4 | .607 |
| Collin Snider | Bos | mr | 28 | 2 | 1 | .500 | 1 | .500 | 1 | 2 | 2 | 1.000 | 7 | 7 | 3 | 29.3 | .620 |
| Jose Soriano | | mr | 25 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 1 | .250 | 29 | 6 | 1 | 68.1 | .604 |
| Mike Soroka | Ari | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 1 | 9 | 2 | .222 | 12 | 12 | 7 | 17.3 | .659 |
| Gregory Soto* | Cle | mr | 29 | 9 | 4 | .444 | 5 | .556 | 18 | 37 | 13 | .351 | 51 | 51 | 15 | 16.2 | .632 |
| Gabe Speier* | Was | mr | 29 | 2 | 1 | .500 | 1 | .500 | 5 | 6 | 1 | .167 | 23 | 23 | 4 | 19.3 | .667 |
| Mitch Spence | SF | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 17 | 1 | 1 | 99.5 | .634 |
| Carson Spiers | Cle | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 1 | .167 | 6 | 6 | 4 | 13.5 | .704 |
| Jeffrey Springs* | Bos | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 103.5 | .663 |
| Garrett Stallings | LAA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 1 | .333 | 16 | 7 | 3 | 63.7 | .633 |
| Ryne Stanek | | mr | 32 | 3 | 1 | .333 | 1 | .333 | 6 | 23 | 10 | .435 | 37 | 37 | 14 | 18.1 | .629 |
| Cody Stashak | Cle | mr | 30 | 2 | 1 | .500 | 1 | .500 | 8 | 16 | 1 | .063 | 37 | 37 | 11 | 18.9 | .651 |
| Josh Staumont | Phi | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 1 | 5 | 3 | .600 | 8 | 8 | 3 | 19.4 | .568 |
| Justin Steele* | Tex | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 99.6 | .640 |
| Brock Stewart | Tex | mr | 32 | 6 | 6 | 1.000 | 0 | .000 | 2 | 5 | 2 | .400 | 22 | 22 | 15 | 15.1 | .636 |
| Gavin Stone | | sp | 25 | 4 | 2 | .500 | 2 | .500 | 7 | 20 | 5 | .250 | 50 | 37 | 14 | 35.8 | .642 |
| Matt Strahm* | Tor | mr | 32 | 6 | 4 | .667 | 2 | .333 | 4 | 19 | 3 | .158 | 38 | 22 | 15 | 47.9 | .631 |
| Hunter Stratton | | mr | 27 | 5 | 5 | 1.000 | 0 | .000 | 2 | 16 | 5 | .313 | 29 | 29 | 16 | 19.2 | .577 |
| Spencer Strider | Sea | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 105.0 | .590 |
| Marcus Stroman | Tam | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 95.2 | .637 |
| Peter Strzelecki | KC | mr | 29 | 11 | 5 | .455 | 6 | .545 | 13 | 44 | 10 | .227 | 84 | 84 | 30 | 17.5 | .629 |
| Jose Suarez* | | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 2 | 9 | 1 | .111 | 23 | 18 | 8 | 40.7 | .639 |
| Ranger Suarez* | ChN | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 100.3 | .633 |
| Robert Suarez | Tam | mr | 33 | 11 | 8 | .727 | 2 | .182 | 11 | 34 | 8 | .235 | 56 | 56 | 22 | 17.1 | .593 |
| Brent Suter* | LAN | mr | 34 | 8 | 2 | .250 | 6 | .750 | 2 | 27 | 5 | .185 | 36 | 36 | 17 | 20.7 | .647 |
| Erik Swanson | SD | mr | 30 | 32 | 28 | .875 | 4 | .125 | 1 | 19 | 5 | .263 | 47 | 47 | 42 | 15.9 | .657 |
| Devin Sweet | Oak | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 1 | 20 | 4 | .200 | 32 | 32 | 16 | 23.4 | .635 |
| Jameson Taillon | Tam | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 94.8 | .644 |
| Dillon Tate | StL | mr | 30 | 2 | 2 | 1.000 | 0 | .000 | 3 | 11 | 2 | .182 | 15 | 15 | 4 | 19.8 | .606 |
| Dylan Tebrake | SD | mr | 24 | 7 | 3 | .429 | 4 | .571 | 10 | 24 | 5 | .208 | 44 | 44 | 15 | 21.3 | .610 |
| Caleb Thielbar* | Pit | mr | 37 | 5 | 1 | .200 | 4 | .800 | 14 | 30 | 5 | .167 | 58 | 58 | 14 | 16.1 | .641 |
| Ryan Thompson | Bos | mr | 32 | 8 | 6 | .750 | 2 | .250 | 6 | 49 | 18 | .367 | 56 | 56 | 25 | 17.9 | .622 |
| Zack Thompson* | SF | sp | 26 | 5 | 4 | .800 | 1 | .200 | 10 | 33 | 11 | .333 | 51 | 43 | 11 | 30.4 | .582 |
| Trent Thornton | Mil | mr | 30 | 0 | 0 | .000 | 0 | .000 | 3 | 18 | 7 | .389 | 24 | 24 | 11 | 21.0 | .638 |
| Ricky Tiedemann* | Tex | sp | 21 | 3 | 2 | .667 | 1 | .333 | 0 | 6 | 2 | .333 | 6 | 6 | 6 | 19.7 | .636 |
| Michael Tonkin | NYN | mr | 34 | 1 | 1 | 1.000 | 0 | .000 | 0 | 5 | 0 | .000 | 4 | 4 | 3 | 10.0 | .550 |
| Blake Treinen | Pit | mr | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 2 | .200 | 11 | 11 | 8 | 19.5 | .626 |
| Edwin Uceta | Pit | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 6 | 0 | .000 | 10 | 8 | 5 | 32.8 | .604 |
| Abner Uribe | Sea | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 2 | 6 | 0 | .000 | 13 | 13 | 6 | 22.4 | .553 |
| Framber Valdez* | LAA | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 99.0 | .657 |
| Reid VanScoter* | KC | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 99.4 | .674 |
| Louie Varland | Atl | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 6 | 14 | 1 | .071 | 45 | 24 | 4 | 56.4 | .642 |
| Mike Vasil | Ari | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 4 | 0 | .000 | 30 | 7 | 4 | 71.8 | .637 |
| Randy Vasquez | Det | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 4 | 2 | 2 | 57.3 | .624 |
| Justin Verlander | SD | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 103.6 | .634 |
| Alex Vesia* | Atl | mr | 28 | 25 | 24 | .960 | 1 | .040 | 2 | 24 | 3 | .125 | 55 | 55 | 41 | 18.3 | .603 |
| Nick Vespi* | Det | mr | 28 | 3 | 3 | 1.000 | 0 | .000 | 12 | 26 | 3 | .115 | 43 | 43 | 13 | 21.5 | .649 |
| Will Vest | | mr | 29 | 2 | 1 | .500 | 1 | .500 | 0 | 10 | 2 | .200 | 25 | 23 | 9 | 22.7 | .625 |
| Thyago Vieira | Mia | mr | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 0 | .000 | 3 | 3 | 2 | 11.7 | .657 |
| Darius Vines | Tor | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 3 | 4 | 0 | .000 | 11 | 11 | 4 | 16.5 | .610 |
| Victor Vodnik | NYA | mr | 24 | 5 | 4 | .800 | 1 | .200 | 4 | 31 | 12 | .387 | 44 | 44 | 19 | 18.2 | .583 |
| Austin Voth | NYN | mr | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 79.9 | .633 |
| Michael Wacha | | sp | 32 | 2 | 2 | 1.000 | 0 | .000 | 0 | 17 | 3 | .176 | 30 | 21 | 10 | 44.4 | .647 |
| Hurston Waldrep | Atl | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 95.1 | .616 |
| Matt Waldron | | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 89.5 | .641 |
| Ryan Walker | | mr | 28 | 12 | 9 | .750 | 3 | .250 | 9 | 15 | 3 | .200 | 40 | 37 | 16 | 22.0 | .635 |
| Taijuan Walker | | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 96.1 | .637 |
| Blake Walston* | ChN | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 102.1 | .606 |
| Will Warren | ChN | sp | 25 | 6 | 2 | .333 | 4 | .667 | 4 | 13 | 5 | .385 | 34 | 29 | 15 | 26.8 | .615 |
| Ryan Weathers* | Col | sp | 24 | 2 | 1 | .500 | 1 | .500 | 0 | 18 | 8 | .444 | 16 | 16 | 6 | 23.3 | .641 |
| Luke Weaver | Tam | sp | 30 | 1 | 0 | .000 | 0 | .000 | 10 | 33 | 14 | .424 | 43 | 43 | 8 | 15.5 | .624 |
| Jacob Webb | Mil | mr | 30 | 1 | 0 | .000 | 1 | 1.000 | 10 | 31 | 13 | .419 | 40 | 40 | 19 | 22.0 | .628 |
| Logan Webb | Oak | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 92.4 | .714 |
| Tyler Wells | StL | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 90.5 | .591 |
| Joey Wentz* | | sp | 26 | 1 | 1 | 1.000 | 0 | .000 | 3 | 4 | 1 | .250 | 12 | 12 | 6 | 22.8 | .639 |
| Hayden Wesneski | Col | sp | 26 | 6 | 2 | .333 | 3 | .500 | 6 | 18 | 5 | .278 | 37 | 29 | 10 | 36.4 | .615 |
| Zack Wheeler | | sp | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 107.4 | .643 |
| Carson Whisenhunt* | KC | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 6 | 2 | .333 | 6 | 5 | 5 | 32.5 | .610 |
| Brendan White | Was | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 2 | 9 | 3 | .333 | 14 | 12 | 4 | 35.6 | .631 |
| Garrett Whitlock | Oak | mr | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 95.8 | .616 |
| Jordan Wicks* | Tam | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 87.0 | .672 |
| Brad Wieck* | Cle | mr | 32 | 2 | 0 | .000 | 2 | 1.000 | 3 | 5 | 1 | .200 | 17 | 17 | 2 | 23.2 | .547 |
| Devin Williams | | cl | 29 | 4 | 4 | 1.000 | 0 | .000 | 2 | 16 | 6 | .375 | 19 | 19 | 12 | 20.1 | .583 |
| Gavin Williams | Ari | sp | 24 | 2 | 1 | .500 | 1 | .500 | 1 | 4 | 2 | .500 | 10 | 8 | 5 | 38.5 | .595 |
| Brandon Williamson* | Col | sp | 26 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 4 | .667 | 4 | 2 | 2 | 64.5 | .578 |
| Bryse Wilson | Tor | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 92.9 | .645 |
| Steven Wilson | Det | mr | 29 | 1 | 1 | 1.000 | 0 | .000 | 2 | 13 | 3 | .231 | 19 | 19 | 6 | 23.1 | .560 |
| Allan Winans | SD | sp | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 1 | 0 | .000 | 29 | 9 | 4 | 71.9 | .643 |
| Josh Winckowski | KC | mr | 26 | 2 | 0 | .000 | 2 | 1.000 | 2 | 6 | 3 | .500 | 36 | 17 | 5 | 55.6 | .634 |
| Josh Winder | Mia | mr | 27 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 2 | 2 | 1 | 26.0 | .615 |
| Keaton Winn | SF | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 12 | 1 | 1 | 89.8 | .631 |
| Bryan Woo | Bos | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 0 | 0 | 90.4 | .638 |
| Alex Wood* | ChN | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 93.7 | .650 |
| Simeon Woods Richardso | | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 16 | 4 | .250 | 18 | 18 | 11 | 21.5 | .623 |
| Yoshinobu Yamamoto | Col | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 94.4 | .646 |
| Kirby Yates | StL | mr | 37 | 1 | 1 | 1.000 | 0 | .000 | 3 | 6 | 2 | .333 | 10 | 10 | 5 | 23.1 | .563 |
| Huascar Ynoa | Mil | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 4 | 2 | 26.5 | .575 |
| Brandon Young | Hou | sp | 25 | 2 | 2 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 7 | 4 | 2 | 57.0 | .612 |
| Ryan Zeferjahn | Bos | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 86.0 | .616 |
| Angel Zerpa* | Bal | sp | 24 | 6 | 2 | .333 | 4 | .667 | 5 | 36 | 11 | .306 | 37 | 37 | 11 | 24.1 | .609 |
| Yosver Zulueta | Col | mr | 26 | 1 | 0 | .000 | 0 | .000 | 0 | 11 | 7 | .636 | 22 | 16 | 3 | 40.5 | .556 |
