Team game results -- 2022 Detroit Tigers
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/8/2022 | | | ChA | L | 7-8 | | Kershaw | L | Hudson,Dan | | Mize | R |
| 4/9/2022 | | | ChA | W | 7-3 | | Senzatela | R | Senzatela | Stammen | Dunning | R |
| 4/10/2022 | | | ChA | W | 18-4 | | Weaver | R | Weaver | | Meyer,M | R |
| 4/11/2022 | | | Bos | L | 4-6 | 10 | Syndergaard | R | Stammen | | Marquez,G | R |
| 4/12/2022 | | | Bos | L | 2-10 | | Valdez,F | L | Valdez,F | | Rasmussen | R |
| 4/13/2022 | | | Bos | W | 6-2 | | Kershaw | L | Kershaw | | Woodruff | R |
| 4/14/2022 | | @ | KC | W | 5-3 | | Senzatela | R | Senzatela | Bleier | Wheeler | R |
| 4/15/2022 | | @ | KC | L | 0-6 | | Weaver | R | Weaver | | Stroman | R |
| 4/16/2022 | | @ | KC | W | 5-3 | | Syndergaard | R | Syndergaard | Stammen | DeSclafani | R |
| 4/17/2022 | | @ | KC | L | 3-5 | | Valdez,F | L | Valdez,F | | Montgomery,J | L |
| 4/19/2022 | | | NYA | W | 2-1 | | Kershaw | L | Kelly,J | | Scherzer | R |
| 4/20/2022 | | | NYA | L | 0-5 | | Senzatela | R | Senzatela | | Verlander | R |
| 4/21/2022 | | | NYA | L | 7-9 | 10 | Weaver | R | Stammen | | Darvish | R |
| 4/22/2022 | | | Col | L | 7-8 | | Syndergaard | R | Syndergaard | | Mikolas | R |
| 4/23/2022 | | | Col | W | 7-5 | | Valdez,F | L | Valdez,F | Stammen | Wright | R |
| 4/24/2022 | | | Col | W | 8-7 | 10 | Kershaw | L | Stammen | | Sandoval | L |
| 4/26/2022 | | @ | Min | L | 2-5 | | Senzatela | R | Senzatela | | Ryan,J | R |
| 4/27/2022 | | @ | Min | W | 8-5 | | Weaver | R | Hudson,Dan | Bleier | Lauer | L |
| 4/28/2022 | | @ | Min | L | 4-5 | 10 | Syndergaard | R | Bass,A | | Flexen | R |
| 4/29/2022 | | @ | LAN | W | 11-2 | | Valdez,F | L | Valdez,F | | Rodriguez,Ye | R |
| 4/30/2022 | | @ | LAN | L | 6-7 | 12 | Kershaw | L | Hudson,Dan | | Beeks | L |
| 5/1/2022 | | @ | LAN | W | 6-4 | | Senzatela | R | Senzatela | Kelly,J | Singer,B | R |
| 5/3/2022 | | | Pit | L | 6-7 | | Weaver | R | Hudson,Dan | | Greinke | R |
| 5/4/2022 | | | Pit | L | 0-12 | | Syndergaard | R | Syndergaard | | Gonzales,M | L |
| 5/5/2022 | | @ | Hou | L | 7-8 | | Valdez,F | L | Stammen | | Ray,R | L |
| 5/6/2022 | | @ | Hou | L | 3-12 | | Kershaw | L | Kershaw | | Rogers,Tr | L |
| 5/7/2022 | | @ | Hou | W | 9-3 | | Senzatela | R | Senzatela | | Hendricks | R |
| 5/8/2022 | | @ | Hou | W | 8-2 | | Weaver | R | Weaver | | Pineda | R |
| 5/9/2022 | | | Oak | W | 7-2 | | Syndergaard | R | Syndergaard | | Gray,Jon | R |
| 5/10/2022 | | | Oak | W | 8-3 | | Valdez,F | L | Valdez,F | | Peterson,Da | L |
| 5/10/2022 | | @ | Oak | L | 2-4 | | Kershaw | L | Kershaw | | Cole,G | R |
| 5/11/2022 | | | Oak | L | 1-4 | | Senzatela | R | Bleier | | Webb,L | R |
| 5/12/2022 | | | Oak | L | 4-9 | | Weaver | R | Weaver | | Eovaldi | R |
| 5/13/2022 | | | Bal | W | 5-3 | | Syndergaard | R | Syndergaard | Stammen | Miller,Bo | R |
| 5/14/2022 | | | Bal | W | 6-2 | | Valdez,F | L | Valdez,F | | Romero,T | R |
| 5/15/2022 | | | Bal | W | 7-4 | | Kershaw | L | Kershaw | Stammen | Frias | R |
| 5/16/2022 | | @ | Tam | L | 1-3 | | Senzatela | R | Senzatela | | Anderson,I | R |
| 5/17/2022 | | @ | Tam | L | 4-5 | 10 | Weaver | R | Stammen | | Skubal | L |
| 5/18/2022 | | @ | Tam | W | 7-6 | 10 | Syndergaard | R | Bleier | Stammen | Hudson,Dak | R |
| 5/20/2022 | | @ | Cle | L | 2-6 | | Valdez,F | L | Valdez,F | | Weiss,R | R |
| 5/21/2022 | | @ | Cle | L | 5-6 | | Bedrosian | R | Bedrosian | | Liberatore | L |
| 5/22/2022 | | @ | Cle | L | 5-7 | | Senzatela | R | Senzatela | | Giolito | R |
| 5/23/2022 | | @ | Min | W | 5-3 | 10 | Weaver | R | Hudson,Dan | Stammen | Ryan,J | R |
| 5/24/2022 | | @ | Min | L | 3-5 | | Syndergaard | R | Syndergaard | | Lauer | L |
| 5/25/2022 | | @ | Min | L | 0-2 | | Valdez,F | L | Valdez,F | | Flexen | R |
| 5/26/2022 | | | Cle | W | 7-6 | | Bedrosian | R | Bass,A | Stammen | Liberatore | L |
| 5/27/2022 | | | Cle | L | 0-5 | | Senzatela | R | Senzatela | | Giolito | R |
| 5/28/2022 | | | Cle | L | 2-13 | | Weaver | R | Weaver | | Buehler | R |
| 5/29/2022 | | | Cle | L | 6-7 | | Syndergaard | R | Syndergaard | | Bieber | R |
| 5/30/2022 | | | Min | W | 5-3 | | Valdez,F | L | Valdez,F | Bedrosian | Flexen | R |
| 5/31/2022 | 1 | | Min | W | 6-1 | | Bedrosian | R | Garrett,A | | Freeland | L |
| 5/31/2022 | 2 | | Min | W | 7-5 | | Senzatela | R | Senzatela | | Taillon | R |
| 6/1/2022 | | | Min | W | 9-6 | | Weaver | R | Hudson,Dan | Kelly,J | Quantrill | R |
| 6/2/2022 | | | Min | L | 2-8 | | Syndergaard | R | Syndergaard | | Lauer | L |
| 6/3/2022 | | @ | NYA | W | 6-2 | | Valdez,F | L | Valdez,F | | Verlander | R |
| 6/4/2022 | | @ | NYA | L | 2-3 | | Hudson,Dan | R | Hudson,Dan | | Darvish | R |
| 6/5/2022 | | @ | NYA | W | 3-0 | | Senzatela | R | Senzatela | Stammen | Stripling | R |
| 6/7/2022 | | @ | Pit | L | 4-5 | | Weaver | R | Weaver | | Gonzales,M | L |
| 6/8/2022 | | @ | Pit | W | 4-2 | | Syndergaard | R | Syndergaard | Stammen | Carrasco | R |
| 6/10/2022 | | | Tor | L | 0-1 | | Valdez,F | L | Valdez,F | | Kilian | R |
| 6/11/2022 | | | Tor | L | 5-13 | | Bedrosian | R | Bedrosian | | Detmers | L |
| 6/12/2022 | | | Tor | W | 12-7 | | Senzatela | R | Senzatela | | Long | L |
| 6/13/2022 | | | ChA | W | 3-2 | | Weaver | R | Weaver | Stammen | Gore,M | L |
| 6/14/2022 | | | ChA | W | 3-2 | | Syndergaard | R | Bleier | Stammen | Henry,T | L |
| 6/15/2022 | | | ChA | W | 7-0 | | Valdez,F | L | Valdez,F | | White,Mit | R |
| 6/16/2022 | | | Tex | W | 6-4 | | Bedrosian | R | Kelly,J | Stammen | Lopez,P | R |
| 6/17/2022 | | | Tex | W | 5-4 | 11 | Senzatela | R | Stammen | | Urquidy | R |
| 6/18/2022 | | | Tex | W | 9-7 | | Weaver | R | Hudson,Dan | | Gonsolin | R |
| 6/19/2022 | | | Tex | W | 6-3 | | Syndergaard | R | Bleier | Stammen | Severino,L | R |
| 6/20/2022 | | @ | Bos | L | 4-5 | | Valdez,F | L | Valdez,F | | Clevinger | R |
| 6/21/2022 | | @ | Bos | L | 5-9 | | Bedrosian | R | Bedrosian | | Marquez,G | R |
| 6/22/2022 | | @ | Bos | L | 2-4 | | Senzatela | R | Senzatela | | Castillo,L | R |
| 6/24/2022 | | @ | Ari | L | 4-5 | | Weaver | R | Stammen | | Fried | L |
| 6/25/2022 | | @ | Ari | L | 0-8 | | Syndergaard | R | Syndergaard | | Dubin | R |
| 6/26/2022 | | @ | Ari | W | 1-0 | | Valdez,F | L | Valdez,F | Stammen | Mahle | R |
| 6/28/2022 | | @ | SF | W | 7-6 | | Bedrosian | R | Bleier | | Myers,T | R |
| 6/29/2022 | | @ | SF | L | 4-6 | | Senzatela | R | Senzatela | | Kopech | R |
| 7/1/2022 | | | KC | W | 5-3 | | Weaver | R | Weaver | Stammen | Castro,M | R |
| 7/2/2022 | | | KC | L | 1-2 | | Syndergaard | R | Syndergaard | | Wheeler | R |
| 7/3/2022 | | | KC | W | 12-4 | | Valdez,F | L | Valdez,F | Bleier | Holton,T | L |
| 7/4/2022 | | | Cle | L | 3-6 | | Bedrosian | R | Bedrosian | | Strahm | L |
| 7/5/2022 | | | Cle | W | 2-1 | | Senzatela | R | Senzatela | Bass,A | Bieber | R |
| 7/6/2022 | | | Cle | L | 2-6 | | Weaver | R | Weaver | | Weiss,R | R |
| 7/7/2022 | | @ | ChA | W | 11-7 | | Syndergaard | R | Syndergaard | | White,Mit | R |
| 7/8/2022 | | @ | ChA | L | 2-5 | | Valdez,F | L | Valdez,F | | Dunning | R |
| 7/9/2022 | | @ | ChA | W | 1-0 | | Bedrosian | R | Pagan | Stammen | Meyer,M | R |
| 7/10/2022 | | @ | ChA | W | 4-2 | 10 | Senzatela | R | Bass,A | | Gore,M | L |
| 7/11/2022 | | @ | KC | L | 3-7 | | Weaver | R | Weaver | | Stroman | R |
| 7/12/2022 | | @ | KC | L | 3-6 | | Syndergaard | R | Syndergaard | | Wheeler | R |
| 7/13/2022 | | @ | KC | W | 7-5 | | Valdez,F | L | Valdez,F | Stammen | Holton,T | L |
| 7/15/2022 | | @ | Cle | L | 0-12 | | Bedrosian | R | Bedrosian | | Giolito | R |
| 7/16/2022 | | @ | Cle | W | 5-4 | | Kelly,J | R | Bleier | Stammen | Strahm | L |
| 7/17/2022 | | @ | Cle | L | 13-16 | 11 | Weaver | R | Bleier | | Bieber | R |
| 7/21/2022 | 1 | @ | Oak | L | 1-5 | | Syndergaard | R | Syndergaard | | Bundy | R |
| 7/21/2022 | 2 | @ | Oak | L | 3-6 | | Valdez,F | L | Valdez,F | | Peterson,Da | L |
| 7/23/2022 | | | Min | W | 11-8 | | Bleier | L | Stammen | | Ryan,J | R |
| 7/24/2022 | | | Min | W | 4-3 | 10 | Garrett,A | L | Kelly,J | | Taillon | R |
| 7/25/2022 | | | SD | W | 11-1 | | Weaver | R | Weaver | | Faedo | R |
| 7/26/2022 | | | SD | L | 4-9 | | Syndergaard | R | Syndergaard | | Bowlan | R |
| 7/27/2022 | | | SD | W | 5-0 | | Valdez,F | L | Valdez,F | | Cabrera,E | R |
| 7/28/2022 | | @ | Tor | W | 5-4 | | Kelly,J | R | Bass,A | Garrett,A | Long | L |
| 7/29/2022 | | @ | Tor | W | 3-1 | | Kuhl | R | Kuhl | Bedrosian | Winckowski | R |
| 7/30/2022 | | @ | Tor | L | 2-10 | | Irvin | L | Irvin | | Vierling | R |
| 7/31/2022 | | @ | Tor | L | 2-4 | | Syndergaard | R | Pagan | | Kilian | R |
| 8/1/2022 | | @ | Min | L | 2-3 | | Valdez,F | L | Valdez,F | | Taillon | R |
| 8/2/2022 | | @ | Min | L | 3-9 | | Kershaw | L | Kershaw | | Lauer | L |
| 8/3/2022 | | @ | Min | L | 6-7 | 12 | Kuhl | R | Bedrosian | | Flexen | R |
| 8/4/2022 | | | Tam | W | 6-5 | | Irvin | L | Pagan | Bleier | Jarvis | R |
| 8/5/2022 | | | Tam | W | 5-4 | | Syndergaard | R | Syndergaard | Bass,A | Garrett,B | L |
| 8/6/2022 | | | Tam | W | 5-4 | | Valdez,F | L | Valdez,F | Akin | Anderson,I | R |
| 8/7/2022 | | | Tam | L | 7-13 | | Kershaw | L | Kershaw | | Lynch | L |
| 8/9/2022 | | | Cle | L | 5-12 | | Kuhl | R | Pagan | | Liberatore | L |
| 8/10/2022 | | | Cle | W | 4-0 | | Irvin | L | Irvin | | Bieber | R |
| 8/11/2022 | | | Cle | W | 5-2 | | Syndergaard | R | Syndergaard | Pagan | Giolito | R |
| 8/12/2022 | | @ | ChA | L | 4-5 | 10 | Valdez,F | L | Kelly,J | | Olson,R | R |
| 8/13/2022 | | @ | ChA | W | 8-7 | 10 | Weaver | R | Bedrosian | | Henry,T | L |
| 8/14/2022 | | @ | ChA | L | 1-4 | | Kuhl | R | Kuhl | | Dunning | R |
| 8/15/2022 | | @ | Cle | L | 2-3 | | Irvin | L | Irvin | | Bieber | R |
| 8/16/2022 | | @ | Cle | L | 3-5 | | Syndergaard | R | Syndergaard | | Giolito | R |
| 8/17/2022 | | @ | Cle | L | 3-10 | | Valdez,F | L | Valdez,F | | Weiss,R | R |
| 8/19/2022 | | | LAA | W | 6-2 | | Weaver | R | Weaver | | Kelly,Me | R |
| 8/20/2022 | | | LAA | L | 2-5 | | Kuhl | R | Kuhl | | Contreras,R | R |
| 8/21/2022 | | | LAA | W | 5-3 | | Irvin | L | Garrett,A | Bleier | Crowe | R |
| 8/23/2022 | | | SF | L | 5-11 | | Syndergaard | R | Syndergaard | | Canning,Gr | R |
| 8/24/2022 | | | SF | W | 9-2 | | Valdez,F | L | Valdez,F | | Myers,T | R |
| 8/26/2022 | | @ | Tex | L | 6-7 | | Weaver | R | Weaver | | Urquidy | R |
| 8/27/2022 | | @ | Tex | L | 0-6 | | Kuhl | R | Kuhl | | Ohtani | R |
| 8/28/2022 | | @ | Tex | L | 5-9 | | Irvin | L | Irvin | | McCullers Jr. | R |
| 8/30/2022 | | | Sea | W | 2-1 | | Syndergaard | R | Bleier | | Kirby,G | R |
| 8/31/2022 | | | Sea | W | 4-3 | | Valdez,F | L | Bleier | | Strider | R |
| 9/1/2022 | | | Sea | L | 6-11 | | Weaver | R | Weaver | | Garcia,LH | R |
| 9/2/2022 | | | KC | L | 2-5 | | Kuhl | R | Pagan | | Holton,T | L |
| 9/3/2022 | | | KC | L | 4-5 | | Irvin | L | Irvin | | Montgomery,J | L |
| 9/4/2022 | | | KC | W | 9-5 | | Syndergaard | R | Syndergaard | | Kelly,Z | R |
| 9/5/2022 | | @ | LAA | W | 11-8 | | Valdez,F | L | Valdez,F | Bleier | Contreras,R | R |
| 9/6/2022 | | @ | LAA | W | 10-3 | | Weaver | R | Weaver | | Junis | R |
| 9/7/2022 | | @ | LAA | L | 3-6 | | Kuhl | R | Bleier | | Valdez,C | R |
| 9/9/2022 | | @ | KC | W | 5-4 | | Irvin | L | Pagan | Kelly,J | Montgomery,J | L |
| 9/10/2022 | | @ | KC | L | 4-7 | 10 | Syndergaard | R | Bleier | | Kelly,Z | R |
| 9/11/2022 | | @ | KC | L | 2-4 | | Valdez,F | L | Valdez,F | | Williams,Tr | R |
| 9/12/2022 | | | Hou | L | 3-4 | | Weaver | R | Weaver | | Ray,R | L |
| 9/13/2022 | | | Hou | W | 6-5 | | Kuhl | R | Kuhl | Bleier | Kowar | R |
| 9/14/2022 | | | Hou | W | 5-4 | | Irvin | L | Garrett,A | | Gallen | R |
| 9/16/2022 | | | ChA | L | 5-9 | | Syndergaard | R | Syndergaard | | Dunning | R |
| 9/17/2022 | | | ChA | L | 4-6 | | Valdez,F | L | Kelly,J | | Seabold | R |
| 9/18/2022 | | | ChA | W | 6-3 | | Weaver | R | Weaver | Bleier | White,Mit | R |
| 9/19/2022 | | @ | Bal | L | 5-6 | | Kuhl | R | Akin | | Miller,Bo | R |
| 9/20/2022 | | @ | Bal | W | 6-3 | | Irvin | L | Irvin | Bedrosian | Romero,T | R |
| 9/21/2022 | | @ | Bal | W | 6-4 | | Syndergaard | R | Syndergaard | Garrett,A | Frias | R |
| 9/23/2022 | | @ | ChA | L | 1-9 | | Valdez,F | L | Valdez,F | | Seabold | R |
| 9/24/2022 | | @ | ChA | W | 6-0 | | Bedrosian | R | Garrett,A | | White,Mit | R |
| 9/25/2022 | | @ | ChA | L | 1-6 | | Kuhl | R | Kuhl | | Olson,R | R |
| 9/27/2022 | | | KC | L | 0-9 | | Irvin | L | Irvin | | Holton,T | L |
| 9/28/2022 | | | KC | L | 2-14 | | Syndergaard | R | Syndergaard | | Kelly,Z | R |
| 9/29/2022 | | | KC | L | 6-7 | 10 | Valdez,F | L | Bedrosian | | Wheeler | R |
| 9/30/2022 | | | Min | W | 4-3 | | Weaver | R | Weaver | Bedrosian | Taillon | R |
| 10/1/2022 | | | Min | L | 0-7 | | Kuhl | R | Kuhl | | Freeland | L |
| 10/2/2022 | | | Min | L | 1-13 | | Irvin | L | Irvin | | Flexen | R |
| 10/3/2022 | | @ | Sea | W | 6-1 | | Syndergaard | R | Syndergaard | | Kirby,G | R |
| 10/4/2022 | 1 | @ | Sea | L | 6-12 | | Valdez,F | L | Pagan | | Garcia,LH | R |
| 10/4/2022 | 2 | @ | Sea | L | 5-7 | | Bedrosian | R | Pagan | | Glasnow | R |
| 10/5/2022 | | @ | Sea | L | 0-12 | | Kuhl | R | Kuhl | | McClanahan | L |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/8/2022 | | | ChA | L | | 7 | 8 | 0 | 1 | .000 | 0-1 | L1 | 1 |
| 4/9/2022 | | | ChA | W | Bryant | 7 | 3 | 1 | 1 | .500 | 1-1 | W1 | 2 |
| 4/10/2022 | | | ChA | W | Abreu,J | 18 | 4 | 2 | 1 | .667 | 2-1 | W2 | 3 |
| 4/11/2022 | | | Bos | L | | 4 | 6 | 2 | 2 | .500 | 2-2 | L1 | 4 |
| 4/12/2022 | | | Bos | L | | 2 | 10 | 2 | 3 | .400 | 2-3 | L2 | 5 |
| 4/13/2022 | | | Bos | W | Mejia,F | 6 | 2 | 3 | 3 | .500 | 3-3 | W1 | 6 |
| 4/14/2022 | | @ | KC | W | Mejia,F | 5 | 3 | 4 | 3 | .571 | 4-3 | W2 | 7 |
| 4/15/2022 | | @ | KC | L | | 0 | 6 | 4 | 4 | .500 | 4-4 | L1 | 8 |
| 4/16/2022 | | @ | KC | W | Swanson,D | 5 | 3 | 5 | 4 | .556 | 5-4 | W1 | 9 |
| 4/17/2022 | | @ | KC | L | | 3 | 5 | 5 | 5 | .500 | 5-5 | L1 | 10 |
| 4/19/2022 | | | NYA | W | Grichuk | 2 | 1 | 6 | 5 | .545 | 6-4 | W1 | 11 |
| 4/20/2022 | | | NYA | L | | 0 | 5 | 6 | 6 | .500 | 5-5 | L1 | 12 |
| 4/21/2022 | | | NYA | L | | 7 | 9 | 6 | 7 | .462 | 4-6 | L2 | 13 |
| 4/22/2022 | | | Col | L | | 7 | 8 | 6 | 8 | .429 | 4-6 | L3 | 14 |
| 4/23/2022 | | | Col | W | Swanson,D | 7 | 5 | 7 | 8 | .467 | 5-5 | W1 | 15 |
| 4/24/2022 | | | Col | W | Machado,M | 8 | 7 | 8 | 8 | .500 | 5-5 | W2 | 16 |
| 4/26/2022 | | @ | Min | L | | 2 | 5 | 8 | 9 | .471 | 4-6 | L1 | 17 |
| 4/27/2022 | | @ | Min | W | Bryant | 8 | 5 | 9 | 9 | .500 | 5-5 | W1 | 18 |
| 4/28/2022 | | @ | Min | L | | 4 | 5 | 9 | 10 | .474 | 4-6 | L1 | 19 |
| 4/29/2022 | | @ | LAN | W | Santander | 11 | 2 | 10 | 10 | .500 | 5-5 | W1 | 20 |
| 4/30/2022 | | @ | LAN | L | | 6 | 7 | 10 | 11 | .476 | 4-6 | L1 | 21 |
| 5/1/2022 | | @ | LAN | W | Nunez,R | 6 | 4 | 11 | 11 | .500 | 5-5 | W1 | 22 |
| 5/3/2022 | | | Pit | L | | 6 | 7 | 11 | 12 | .478 | 5-5 | L1 | 23 |
| 5/4/2022 | | | Pit | L | | 0 | 12 | 11 | 13 | .458 | 5-5 | L2 | 24 |
| 5/5/2022 | | @ | Hou | L | | 7 | 8 | 11 | 14 | .440 | 4-6 | L3 | 25 |
| 5/6/2022 | | @ | Hou | L | | 3 | 12 | 11 | 15 | .423 | 3-7 | L4 | 26 |
| 5/7/2022 | | @ | Hou | W | Machado,M | 9 | 3 | 12 | 15 | .444 | 4-6 | W1 | 27 |
| 5/8/2022 | | @ | Hou | W | Jimenez,E | 8 | 2 | 13 | 15 | .464 | 4-6 | W2 | 28 |
| 5/9/2022 | | | Oak | W | Grichuk | 7 | 2 | 14 | 15 | .483 | 5-5 | W3 | 29 |
| 5/10/2022 | | | Oak | W | Swanson,D | 8 | 3 | 15 | 15 | .500 | 5-5 | W4 | 30 |
| 5/10/2022 | | @ | Oak | L | | 2 | 4 | 15 | 16 | .484 | 5-5 | L1 | 31 |
| 5/11/2022 | | | Oak | L | | 1 | 4 | 15 | 17 | .469 | 4-6 | L2 | 32 |
| 5/12/2022 | | | Oak | L | | 4 | 9 | 15 | 18 | .455 | 4-6 | L3 | 33 |
| 5/13/2022 | | | Bal | W | Peralta,D | 5 | 3 | 16 | 18 | .471 | 5-5 | W1 | 34 |
| 5/14/2022 | | | Bal | W | Peralta,D | 6 | 2 | 17 | 18 | .486 | 6-4 | W2 | 35 |
| 5/15/2022 | | | Bal | W | Machado,M | 7 | 4 | 18 | 18 | .500 | 7-3 | W3 | 36 |
| 5/16/2022 | | @ | Tam | L | | 1 | 3 | 18 | 19 | .486 | 6-4 | L1 | 37 |
| 5/17/2022 | | @ | Tam | L | | 4 | 5 | 18 | 20 | .474 | 5-5 | L2 | 38 |
| 5/18/2022 | | @ | Tam | W | Santander | 7 | 6 | 19 | 20 | .487 | 5-5 | W1 | 39 |
| 5/20/2022 | | @ | Cle | L | | 2 | 6 | 19 | 21 | .475 | 4-6 | L1 | 40 |
| 5/21/2022 | | @ | Cle | L | | 5 | 6 | 19 | 22 | .463 | 4-6 | L2 | 41 |
| 5/22/2022 | | @ | Cle | L | | 5 | 7 | 19 | 23 | .452 | 4-6 | L3 | 42 |
| 5/23/2022 | | @ | Min | W | Jimenez,E | 5 | 3 | 20 | 23 | .465 | 5-5 | W1 | 43 |
| 5/24/2022 | | @ | Min | L | | 3 | 5 | 20 | 24 | .455 | 4-6 | L1 | 44 |
| 5/25/2022 | | @ | Min | L | | 0 | 2 | 20 | 25 | .444 | 3-7 | L2 | 45 |
| 5/26/2022 | | | Cle | W | Abreu,J | 7 | 6 | 21 | 25 | .457 | 3-7 | W1 | 46 |
| 5/27/2022 | | | Cle | L | | 0 | 5 | 21 | 26 | .447 | 3-7 | L1 | 47 |
| 5/28/2022 | | | Cle | L | | 2 | 13 | 21 | 27 | .438 | 3-7 | L2 | 48 |
| 5/29/2022 | | | Cle | L | | 6 | 7 | 21 | 28 | .429 | 2-8 | L3 | 49 |
| 5/30/2022 | | | Min | W | | 5 | 3 | 22 | 28 | .440 | 3-7 | W1 | 50 |
| 5/31/2022 | 1 | | Min | W | Altuve | 6 | 1 | 23 | 28 | .451 | 4-6 | W2 | 51 |
| 5/31/2022 | 2 | | Min | W | Altuve | 7 | 5 | 24 | 28 | .462 | 5-5 | W3 | 52 |
| 6/1/2022 | | | Min | W | Grichuk | 9 | 6 | 25 | 28 | .472 | 5-5 | W4 | 53 |
| 6/2/2022 | | | Min | L | | 2 | 8 | 25 | 29 | .463 | 5-5 | L1 | 54 |
| 6/3/2022 | | @ | NYA | W | Abreu,J | 6 | 2 | 26 | 29 | .473 | 6-4 | W1 | 55 |
| 6/4/2022 | | @ | NYA | L | | 2 | 3 | 26 | 30 | .464 | 5-5 | L1 | 56 |
| 6/5/2022 | | @ | NYA | W | Abreu,J | 3 | 0 | 27 | 30 | .474 | 6-4 | W1 | 57 |
| 6/7/2022 | | @ | Pit | L | | 4 | 5 | 27 | 31 | .466 | 6-4 | L1 | 58 |
| 6/8/2022 | | @ | Pit | W | Swanson,D | 4 | 2 | 28 | 31 | .475 | 7-3 | W1 | 59 |
| 6/10/2022 | | | Tor | L | | 0 | 1 | 28 | 32 | .467 | 6-4 | L1 | 60 |
| 6/11/2022 | | | Tor | L | | 5 | 13 | 28 | 33 | .459 | 5-5 | L2 | 61 |
| 6/12/2022 | | | Tor | W | Jimenez,E | 12 | 7 | 29 | 33 | .468 | 5-5 | W1 | 62 |
| 6/13/2022 | | | ChA | W | Grichuk | 3 | 2 | 30 | 33 | .476 | 5-5 | W2 | 63 |
| 6/14/2022 | | | ChA | W | Jimenez,E | 3 | 2 | 31 | 33 | .484 | 6-4 | W3 | 64 |
| 6/15/2022 | | | ChA | W | Peralta,D | 7 | 0 | 32 | 33 | .492 | 6-4 | W4 | 65 |
| 6/16/2022 | | | Tex | W | Jimenez,E | 6 | 4 | 33 | 33 | .500 | 7-3 | W5 | 66 |
| 6/17/2022 | | | Tex | W | | 5 | 4 | 34 | 33 | .507 | 7-3 | W6 | 67 |
| 6/18/2022 | | | Tex | W | Nunez,R | 9 | 7 | 35 | 33 | .515 | 8-2 | W7 | 68 |
| 6/19/2022 | | | Tex | W | Altuve | 6 | 3 | 36 | 33 | .522 | 8-2 | W8 | 69 |
| 6/20/2022 | | @ | Bos | L | | 4 | 5 | 36 | 34 | .514 | 8-2 | L1 | 70 |
| 6/21/2022 | | @ | Bos | L | | 5 | 9 | 36 | 35 | .507 | 8-2 | L2 | 71 |
| 6/22/2022 | | @ | Bos | L | | 2 | 4 | 36 | 36 | .500 | 7-3 | L3 | 72 |
| 6/24/2022 | | @ | Ari | L | | 4 | 5 | 36 | 37 | .493 | 6-4 | L4 | 73 |
| 6/25/2022 | | @ | Ari | L | | 0 | 8 | 36 | 38 | .486 | 5-5 | L5 | 74 |
| 6/26/2022 | | @ | Ari | W | Jimenez,E | 1 | 0 | 37 | 38 | .493 | 5-5 | W1 | 75 |
| 6/28/2022 | | @ | SF | W | Machado,M | 7 | 6 | 38 | 38 | .500 | 5-5 | W2 | 76 |
| 6/29/2022 | | @ | SF | L | | 4 | 6 | 38 | 39 | .494 | 4-6 | L1 | 77 |
| 7/1/2022 | | | KC | W | Abreu,J | 5 | 3 | 39 | 39 | .500 | 4-6 | W1 | 78 |
| 7/2/2022 | | | KC | L | | 1 | 2 | 39 | 40 | .494 | 3-7 | L1 | 79 |
| 7/3/2022 | | | KC | W | Nunez,R | 12 | 4 | 40 | 40 | .500 | 4-6 | W1 | 80 |
| 7/4/2022 | | | Cle | L | | 3 | 6 | 40 | 41 | .494 | 4-6 | L1 | 81 |
| 7/5/2022 | | | Cle | W | Peralta,D | 2 | 1 | 41 | 41 | .500 | 5-5 | W1 | 82 |
| 7/6/2022 | | | Cle | L | | 2 | 6 | 41 | 42 | .494 | 5-5 | L1 | 83 |
| 7/7/2022 | | @ | ChA | W | Altuve | 11 | 7 | 42 | 42 | .500 | 6-4 | W1 | 84 |
| 7/8/2022 | | @ | ChA | L | | 2 | 5 | 42 | 43 | .494 | 5-5 | L1 | 85 |
| 7/9/2022 | | @ | ChA | W | Abreu,J | 1 | 0 | 43 | 43 | .500 | 5-5 | W1 | 86 |
| 7/10/2022 | | @ | ChA | W | Altuve | 4 | 2 | 44 | 43 | .506 | 6-4 | W2 | 87 |
| 7/11/2022 | | @ | KC | L | | 3 | 7 | 44 | 44 | .500 | 5-5 | L1 | 88 |
| 7/12/2022 | | @ | KC | L | | 3 | 6 | 44 | 45 | .494 | 5-5 | L2 | 89 |
| 7/13/2022 | | @ | KC | W | Abreu,J | 7 | 5 | 45 | 45 | .500 | 5-5 | W1 | 90 |
| 7/15/2022 | | @ | Cle | L | | 0 | 12 | 45 | 46 | .495 | 5-5 | L1 | 91 |
| 7/16/2022 | | @ | Cle | W | | 5 | 4 | 46 | 46 | .500 | 5-5 | W1 | 92 |
| 7/17/2022 | | @ | Cle | L | | 13 | 16 | 46 | 47 | .495 | 5-5 | L1 | 93 |
| 7/21/2022 | 1 | @ | Oak | L | | 1 | 5 | 46 | 48 | .489 | 4-6 | L2 | 94 |
| 7/21/2022 | 2 | @ | Oak | L | | 3 | 6 | 46 | 49 | .484 | 4-6 | L3 | 95 |
| 7/23/2022 | | | Min | W | Santander | 11 | 8 | 47 | 49 | .490 | 4-6 | W1 | 96 |
| 7/24/2022 | | | Min | W | Nunez,R | 4 | 3 | 48 | 49 | .495 | 4-6 | W2 | 97 |
| 7/25/2022 | | | SD | W | Gordon,N | 11 | 1 | 49 | 49 | .500 | 5-5 | W3 | 98 |
| 7/26/2022 | | | SD | L | | 4 | 9 | 49 | 50 | .495 | 5-5 | L1 | 99 |
| 7/27/2022 | | | SD | W | Altuve | 5 | 0 | 50 | 50 | .500 | 5-5 | W1 | 100 |
| 7/28/2022 | | @ | Tor | W | Altuve | 5 | 4 | 51 | 50 | .505 | 6-4 | W2 | 101 |
| 7/29/2022 | | @ | Tor | W | Jimenez,E | 3 | 1 | 52 | 50 | .510 | 6-4 | W3 | 102 |
| 7/30/2022 | | @ | Tor | L | | 2 | 10 | 52 | 51 | .505 | 6-4 | L1 | 103 |
| 7/31/2022 | | @ | Tor | L | | 2 | 4 | 52 | 52 | .500 | 6-4 | L2 | 104 |
| 8/1/2022 | | @ | Min | L | | 2 | 3 | 52 | 53 | .495 | 6-4 | L3 | 105 |
| 8/2/2022 | | @ | Min | L | | 3 | 9 | 52 | 54 | .491 | 5-5 | L4 | 106 |
| 8/3/2022 | | @ | Min | L | | 6 | 7 | 52 | 55 | .486 | 4-6 | L5 | 107 |
| 8/4/2022 | | | Tam | W | Altuve | 6 | 5 | 53 | 55 | .491 | 4-6 | W1 | 108 |
| 8/5/2022 | | | Tam | W | Jimenez,E | 5 | 4 | 54 | 55 | .495 | 5-5 | W2 | 109 |
| 8/6/2022 | | | Tam | W | | 5 | 4 | 55 | 55 | .500 | 5-5 | W3 | 110 |
| 8/7/2022 | | | Tam | L | | 7 | 13 | 55 | 56 | .495 | 4-6 | L1 | 111 |
| 8/9/2022 | | | Cle | L | | 5 | 12 | 55 | 57 | .491 | 3-7 | L2 | 112 |
| 8/10/2022 | | | Cle | W | Jimenez,E | 4 | 0 | 56 | 57 | .496 | 4-6 | W1 | 113 |
| 8/11/2022 | | | Cle | W | Jimenez,E | 5 | 2 | 57 | 57 | .500 | 5-5 | W2 | 114 |
| 8/12/2022 | | @ | ChA | L | | 4 | 5 | 57 | 58 | .496 | 5-5 | L1 | 115 |
| 8/13/2022 | | @ | ChA | W | Machado,M | 8 | 7 | 58 | 58 | .500 | 6-4 | W1 | 116 |
| 8/14/2022 | | @ | ChA | L | | 1 | 4 | 58 | 59 | .496 | 6-4 | L1 | 117 |
| 8/15/2022 | | @ | Cle | L | | 2 | 3 | 58 | 60 | .492 | 5-5 | L2 | 118 |
| 8/16/2022 | | @ | Cle | L | | 3 | 5 | 58 | 61 | .487 | 4-6 | L3 | 119 |
| 8/17/2022 | | @ | Cle | L | | 3 | 10 | 58 | 62 | .483 | 3-7 | L4 | 120 |
| 8/19/2022 | | | LAA | W | Machado,M | 6 | 2 | 59 | 62 | .488 | 4-6 | W1 | 121 |
| 8/20/2022 | | | LAA | L | | 2 | 5 | 59 | 63 | .484 | 4-6 | L1 | 122 |
| 8/21/2022 | | | LAA | W | Abreu,J | 5 | 3 | 60 | 63 | .488 | 4-6 | W1 | 123 |
| 8/23/2022 | | | SF | L | | 5 | 11 | 60 | 64 | .484 | 3-7 | L1 | 124 |
| 8/24/2022 | | | SF | W | Machado,M | 9 | 2 | 61 | 64 | .488 | 4-6 | W1 | 125 |
| 8/26/2022 | | @ | Tex | L | | 6 | 7 | 61 | 65 | .484 | 3-7 | L1 | 126 |
| 8/27/2022 | | @ | Tex | L | | 0 | 6 | 61 | 66 | .480 | 3-7 | L2 | 127 |
| 8/28/2022 | | @ | Tex | L | | 5 | 9 | 61 | 67 | .477 | 3-7 | L3 | 128 |
| 8/30/2022 | | | Sea | W | Nunez,R | 2 | 1 | 62 | 67 | .481 | 4-6 | W1 | 129 |
| 8/31/2022 | | | Sea | W | Machado,M | 4 | 3 | 63 | 67 | .485 | 5-5 | W2 | 130 |
| 9/1/2022 | | | Sea | L | | 6 | 11 | 63 | 68 | .481 | 4-6 | L1 | 131 |
| 9/2/2022 | | | KC | L | | 2 | 5 | 63 | 69 | .477 | 4-6 | L2 | 132 |
| 9/3/2022 | | | KC | L | | 4 | 5 | 63 | 70 | .474 | 3-7 | L3 | 133 |
| 9/4/2022 | | | KC | W | Peralta,D | 9 | 5 | 64 | 70 | .478 | 4-6 | W1 | 134 |
| 9/5/2022 | | @ | LAA | W | | 11 | 8 | 65 | 70 | .481 | 4-6 | W2 | 135 |
| 9/6/2022 | | @ | LAA | W | Jimenez,E | 10 | 3 | 66 | 70 | .485 | 5-5 | W3 | 136 |
| 9/7/2022 | | @ | LAA | L | | 3 | 6 | 66 | 71 | .482 | 5-5 | L1 | 137 |
| 9/9/2022 | | @ | KC | W | Abreu,J | 5 | 4 | 67 | 71 | .486 | 6-4 | W1 | 138 |
| 9/10/2022 | | @ | KC | L | | 4 | 7 | 67 | 72 | .482 | 5-5 | L1 | 139 |
| 9/11/2022 | | @ | KC | L | | 2 | 4 | 67 | 73 | .479 | 4-6 | L2 | 140 |
| 9/12/2022 | | | Hou | L | | 3 | 4 | 67 | 74 | .475 | 4-6 | L3 | 141 |
| 9/13/2022 | | | Hou | W | Santander | 6 | 5 | 68 | 74 | .479 | 5-5 | W1 | 142 |
| 9/14/2022 | | | Hou | W | Jimenez,E | 5 | 4 | 69 | 74 | .483 | 6-4 | W2 | 143 |
| 9/16/2022 | | | ChA | L | | 5 | 9 | 69 | 75 | .479 | 5-5 | L1 | 144 |
| 9/17/2022 | | | ChA | L | | 4 | 6 | 69 | 76 | .476 | 4-6 | L2 | 145 |
| 9/18/2022 | | | ChA | W | Nunez,R | 6 | 3 | 70 | 76 | .479 | 4-6 | W1 | 146 |
| 9/19/2022 | | @ | Bal | L | | 5 | 6 | 70 | 77 | .476 | 4-6 | L1 | 147 |
| 9/20/2022 | | @ | Bal | W | Abreu,J | 6 | 3 | 71 | 77 | .480 | 4-6 | W1 | 148 |
| 9/21/2022 | | @ | Bal | W | Abreu,J | 6 | 4 | 72 | 77 | .483 | 5-5 | W2 | 149 |
| 9/23/2022 | | @ | ChA | L | | 1 | 9 | 72 | 78 | .480 | 5-5 | L1 | 150 |
| 9/24/2022 | | @ | ChA | W | Peralta,D | 6 | 0 | 73 | 78 | .483 | 6-4 | W1 | 151 |
| 9/25/2022 | | @ | ChA | L | | 1 | 6 | 73 | 79 | .480 | 5-5 | L1 | 152 |
| 9/27/2022 | | | KC | L | | 0 | 9 | 73 | 80 | .477 | 4-6 | L2 | 153 |
| 9/28/2022 | | | KC | L | | 2 | 14 | 73 | 81 | .474 | 4-6 | L3 | 154 |
| 9/29/2022 | | | KC | L | | 6 | 7 | 73 | 82 | .471 | 4-6 | L4 | 155 |
| 9/30/2022 | | | Min | W | | 4 | 3 | 74 | 82 | .474 | 4-6 | W1 | 156 |
| 10/1/2022 | | | Min | L | | 0 | 7 | 74 | 83 | .471 | 4-6 | L1 | 157 |
| 10/2/2022 | | | Min | L | | 1 | 13 | 74 | 84 | .468 | 3-7 | L2 | 158 |
| 10/3/2022 | | @ | Sea | W | Santander | 6 | 1 | 75 | 84 | .472 | 3-7 | W1 | 159 |
| 10/4/2022 | 1 | @ | Sea | L | | 6 | 12 | 75 | 85 | .469 | 3-7 | L1 | 160 |
| 10/4/2022 | 2 | @ | Sea | L | | 5 | 7 | 75 | 86 | .466 | 2-8 | L2 | 161 |
| 10/5/2022 | | @ | Sea | L | | 0 | 12 | 75 | 87 | .463 | 2-8 | L3 | 162 |
