Team game results -- 2021 Chicago (N) Cubs
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/1/2021 | | | Pit | L | 1-2 | | Minor | L | Minor | | Hill,R | L |
| 4/3/2021 | | | Pit | L | 5-7 | | Keuchel | L | Keuchel | | Odorizzi | R |
| 4/4/2021 | | | Pit | W | 6-5 | | Green,C | R | Hendriks | | Velasquez | R |
| 4/5/2021 | | | Mil | L | 2-3 | | Kittredge | R | Kittredge | | Bassitt | R |
| 4/6/2021 | | | Mil | L | 5-9 | | Happ,J | L | Happ,J | | Manaea | L |
| 4/7/2021 | | | Mil | W | 8-3 | | Minor | L | Minor | | Smyly | L |
| 4/8/2021 | | @ | Pit | L | 2-10 | | Pierpont | R | Pierpont | | Odorizzi | R |
| 4/10/2021 | | @ | Pit | W | 4-1 | | Kittredge | R | Kittredge | Martin,Ch | Velasquez | R |
| 4/11/2021 | | @ | Pit | L | 0-1 | | Happ,J | L | Martin,Ch | | Martinez,C | R |
| 4/12/2021 | | @ | Mil | W | 8-1 | | Minor | L | Minor | | Bassitt | R |
| 4/13/2021 | | @ | Mil | W | 3-2 | | Green,C | R | Green,C | Hendriks | Manaea | L |
| 4/14/2021 | | @ | Mil | L | 1-5 | | Keuchel | L | Keuchel | | Cease | R |
| 4/16/2021 | | | Atl | W | 7-1 | | Happ,J | L | Happ,J | Lindgren | Kay | L |
| 4/17/2021 | | | Atl | W | 4-1 | | Minor | L | Minor | Hendriks | Newsome | R |
| 4/18/2021 | | | Atl | W | 6-5 | 10 | Green,C | R | Montas | | Plesac | R |
| 4/20/2021 | | | NYN | W | 12-1 | | Keuchel | L | Keuchel | | Price | L |
| 4/21/2021 | | | NYN | L | 0-5 | | Wood,A | L | Wood,A | | McHugh | R |
| 4/22/2021 | | | NYN | L | 3-4 | 11 | Minor | L | Kittredge | | Newcomb | L |
| 4/23/2021 | | | Mil | W | 6-4 | | Green,C | R | Green,C | Kittredge | Manaea | L |
| 4/24/2021 | | | Mil | L | 1-3 | | Happ,J | L | Happ,J | | Woods Richardsn | R |
| 4/25/2021 | | | Mil | W | 9-7 | 10 | Keuchel | L | Barlow,S | | Smyly | L |
| 4/26/2021 | | @ | Atl | L | 5-6 | | Wood,A | L | Valdez,C | | Castano | L |
| 4/27/2021 | | @ | Atl | L | 2-3 | | Minor | L | Minor | | Yajure | R |
| 4/28/2021 | | @ | Atl | W | 6-5 | | Green,C | R | Green,C | Hendriks | Kay | L |
| 4/29/2021 | | @ | Atl | L | 2-3 | 10 | Happ,J | L | Kittredge | | Newsome | R |
| 4/30/2021 | | @ | Cin | W | 12-4 | | Keuchel | L | Keuchel | | Green,J | R |
| 5/1/2021 | | @ | Cin | L | 0-5 | | Wood,A | L | Wood,A | | Gallen | R |
| 5/2/2021 | | @ | Cin | L | 0-1 | | Minor | L | Minor | | Nelson,Ji | R |
| 5/3/2021 | | | LAN | W | 6-5 | | Green,C | R | Pierpont | Hendriks | Suter | L |
| 5/4/2021 | | | LAN | W | 6-3 | | Happ,J | L | Happ,J | Hendriks | Borucki | L |
| 5/5/2021 | | | LAN | L | 1-3 | | Keuchel | L | Keuchel | | Perez,Ma | L |
| 5/7/2021 | | | Pit | L | 2-5 | 10 | Wood,A | L | Montas | | Hill,R | L |
| 5/8/2021 | | | Pit | W | 12-1 | | Minor | L | Minor | | Gore,M | L |
| 5/9/2021 | | | Pit | L | 3-6 | | Green,C | R | Montas | | Velasquez | R |
| 5/11/2021 | | @ | Cle | L | 3-4 | | Keuchel | L | Keuchel | | Keller,M | R |
| 5/12/2021 | | @ | Cle | L | 3-4 | | Wood,A | L | Wood,A | | Wacha | R |
| 5/14/2021 | | @ | Det | L | 1-2 | | Minor | L | Lindgren | | Hendricks | R |
| 5/15/2021 | | @ | Det | W | 7-4 | 10 | Green,C | R | Hendriks | | Springs | L |
| 5/16/2021 | | @ | Det | L | 2-3 | | Keuchel | L | Kittredge | | Giolito | R |
| 5/17/2021 | | | Was | L | 2-4 | | Pierpont | R | Barlow,S | | Pearson | R |
| 5/18/2021 | | | Was | W | 6-3 | | Minor | L | Lindgren | | Bieber | R |
| 5/19/2021 | | | Was | W | 8-1 | | Green,C | R | Green,C | | Peralta,F | R |
| 5/20/2021 | | | Was | W | 6-4 | | Keuchel | L | Keuchel | Hendriks | Lucchesi | L |
| 5/21/2021 | | @ | StL | L | 3-4 | 14 | Kittredge | R | Martin,Ch | | Wilson,Bry | R |
| 5/22/2021 | | @ | StL | L | 2-3 | | Wood,A | L | Wood,A | | Ivey | R |
| 5/23/2021 | | @ | StL | W | 7-1 | | Minor | L | Minor | | Gonzales | L |
| 5/25/2021 | | @ | Pit | L | 3-8 | | Green,C | R | Green,C | | Hill,R | L |
| 5/26/2021 | | @ | Pit | W | 7-0 | | Keuchel | L | Keuchel | | Velasquez | R |
| 5/27/2021 | | @ | Pit | W | 4-3 | 10 | Kittredge | R | Fairbanks | Hendriks | Bumgarner | L |
| 5/28/2021 | | | Cin | L | 2-5 | | Minor | L | Fairbanks | | Dobnak | R |
| 5/29/2021 | | | Cin | W | 7-2 | | Wood,A | L | Wood,A | | Nelson,Ji | R |
| 5/30/2021 | | | Cin | L | 3-9 | 11 | Green,C | R | Lindgren | | Davies | R |
| 5/31/2021 | | | SD | W | 5-0 | | Keuchel | L | Keuchel | | Nelson,N | R |
| 6/1/2021 | | | SD | L | 2-4 | | Kittredge | R | Kittredge | | Freeland | L |
| 6/2/2021 | | | SD | L | 5-6 | | Minor | L | Minor | | Dunning | R |
| 6/3/2021 | | @ | SF | W | 3-1 | | Wood,A | L | Wood,A | Hendriks | Kopech | R |
| 6/4/2021 | | @ | SF | W | 1-0 | | Green,C | R | Green,C | Hendriks | Phillips,T | R |
| 6/5/2021 | | @ | SF | W | 4-2 | 11 | Keuchel | L | Lindgren | Pierpont | Hjelle | R |
| 6/6/2021 | | @ | SF | W | 8-7 | 11 | Kittredge | R | Martin,Ch | | Canning,Gr | R |
| 6/7/2021 | | @ | SD | W | 7-4 | | Minor | L | Minor | Fairbanks | Garcia,D | R |
| 6/8/2021 | | @ | SD | L | 1-5 | | Wood,A | L | Wood,A | | Nelson,N | R |
| 6/9/2021 | | @ | SD | L | 2-6 | | Green,C | R | Lindgren | | Freeland | L |
| 6/11/2021 | | | StL | L | 1-2 | | Keuchel | L | Keuchel | | Ponce de Leon | R |
| 6/12/2021 | | | StL | W | 3-1 | | Kittredge | R | Kittredge | Hendriks | Wilson,Bry | R |
| 6/13/2021 | | | StL | L | 0-4 | | Minor | L | Minor | | Ivey | R |
| 6/14/2021 | | @ | NYN | W | 3-1 | | Green,C | R | Green,C | Hendriks | Lugo,S | R |
| 6/15/2021 | | @ | NYN | L | 4-6 | | Wood,A | L | Wood,A | | Greinke | R |
| 6/16/2021 | | @ | NYN | W | 7-4 | | Keuchel | L | Keuchel | Hendriks | Price | L |
| 6/17/2021 | | @ | NYN | L | 1-2 | | Kittredge | R | Kittredge | | McHugh | R |
| 6/18/2021 | | | Mia | L | 0-7 | | Pierpont | R | Pierpont | | Rodriguez,E | L |
| 6/19/2021 | | | Mia | W | 4-3 | | Green,C | R | Green,C | Hendriks | Maeda | R |
| 6/20/2021 | | | Mia | L | 2-7 | | Wood,A | L | Wood,A | | Houser | R |
| 6/21/2021 | | | Cle | W | 10-3 | | Minor | L | Minor | | Valdez,F | L |
| 6/22/2021 | | | Cle | L | 5-6 | | Keuchel | L | Keuchel | | Montgomery,J | L |
| 6/24/2021 | | @ | LAN | W | 9-0 | | Green,C | R | Green,C | | Suter | L |
| 6/25/2021 | | @ | LAN | W | 3-0 | | Kittredge | R | Kittredge | Hendriks | Ryu | L |
| 6/26/2021 | | @ | LAN | L | 6-7 | | Minor | L | Hendriks | | Lynn | R |
| 6/27/2021 | | @ | LAN | L | 1-2 | | Keuchel | L | Keuchel | | Borucki | L |
| 6/28/2021 | | @ | Mil | W | 5-2 | 10 | Green,C | R | Hendriks | | Lindblom | R |
| 6/29/2021 | | @ | Mil | W | 7-5 | | Wood,A | L | Wood,A | | Woods Richardsn | R |
| 6/30/2021 | | @ | Mil | L | 3-4 | | Kittredge | R | Barlow,S | | Bassitt | R |
| 7/2/2021 | | @ | Cin | W | 11-10 | | Minor | L | Fairbanks | Hendriks | Nelson,Ji | R |
| 7/3/2021 | | @ | Cin | L | 1-3 | | Keuchel | L | Keuchel | | Jefferies | R |
| 7/4/2021 | | @ | Cin | L | 6-7 | | Green,C | R | Hendriks | | Green,J | R |
| 7/5/2021 | | | Phi | W | 5-3 | | Kittredge | R | Fairbanks | Barlow,S | Stratton | R |
| 7/6/2021 | | | Phi | L | 2-6 | | Wood,A | L | Wood,A | | Nola,Aa | R |
| 7/7/2021 | | | Phi | W | 5-2 | | Minor | L | Minor | Hendriks | Morton | R |
| 7/8/2021 | | | Phi | W | 6-2 | | Keuchel | L | Keuchel | | Heaney | L |
| 7/9/2021 | | | StL | W | 8-3 | | Green,C | R | Green,C | Lindgren | Ponce de Leon | R |
| 7/10/2021 | | | StL | W | 13-3 | | Kittredge | R | Kittredge | | Wilson,Bry | R |
| 7/11/2021 | | | StL | W | 2-1 | 10 | Minor | L | Pierpont | | Gonzales | L |
| 7/16/2021 | | @ | Ari | L | 4-5 | | Pierpont | R | Martin,Ch | | Burnes | R |
| 7/17/2021 | | @ | Ari | L | 1-2 | | Minor | L | Barlow,S | | Fried | L |
| 7/18/2021 | | @ | Ari | W | 4-0 | | Keuchel | L | Keuchel | | Mahle | R |
| 7/19/2021 | | @ | StL | L | 9-10 | | Green,C | R | Hendriks | | Wilson,Bry | R |
| 7/20/2021 | | @ | StL | W | 10-4 | | Kittredge | R | Kittredge | | Muller | L |
| 7/21/2021 | | @ | StL | W | 4-1 | | Keuchel | L | Pierpont | Lindgren | Martin,Co | R |
| 7/22/2021 | | @ | StL | W | 7-6 | 10 | Minor | L | Barlow,S | Pierpont | Chavez,J | R |
| 7/23/2021 | | | Ari | W | 6-1 | | Wood,A | L | Wood,A | | Fried | L |
| 7/24/2021 | | | Ari | L | 3-4 | 10 | Green,C | R | Hendriks | | Mahle | R |
| 7/25/2021 | | | Ari | L | 3-5 | | Kittredge | R | Kittredge | | Loaisiga | R |
| 7/26/2021 | | | Cin | W | 4-3 | | Keuchel | L | Pierpont | | Jefferies | R |
| 7/27/2021 | | | Cin | W | 7-4 | | Minor | L | Fairbanks | | Green,J | R |
| 7/28/2021 | | | Cin | L | 4-9 | | Wood,A | L | Lindgren | | Davies | R |
| 7/29/2021 | | | Cin | W | 5-2 | | Green,C | R | Green,C | Hendriks | Gallen | R |
| 7/30/2021 | | @ | Was | W | 5-4 | 10 | Kittredge | R | Hendriks | Pierpont | German | R |
| 7/31/2021 | | @ | Was | L | 4-5 | 10 | Keuchel | L | Pierpont | | Anderson,Ty | L |
| 8/1/2021 | | @ | Was | L | 1-3 | | Minor | L | Minor | | Flexen | R |
| 8/3/2021 | | @ | Col | W | 4-1 | | Montas | R | Montas | Hendriks | Garcia,D | R |
| 8/4/2021 | | @ | Col | L | 3-8 | | Green,C | R | Green,C | | Foltynewicz | R |
| 8/5/2021 | | @ | Col | L | 2-4 | | Kittredge | R | Barlow,S | | Gray,S | R |
| 8/6/2021 | | | ChA | W | 3-2 | | Keuchel | L | Lindgren | | Seabold | R |
| 8/7/2021 | | | ChA | W | 4-2 | | Minor | L | Minor | Hendriks | White,Mit | R |
| 8/8/2021 | | | ChA | L | 2-3 | | Wood,A | L | Barlow,S | | de la Cruz,J | R |
| 8/9/2021 | | | Mil | W | 7-0 | | McKay | L | McKay | | Manaea | L |
| 8/10/2021 | | | Mil | L | 3-4 | | Kittredge | R | Hendriks | | Clarke | R |
| 8/11/2021 | | | Mil | W | 11-2 | | Keuchel | L | Keuchel | | Woods Richardsn | R |
| 8/12/2021 | | | Mil | W | 11-7 | | Minor | L | Barlow,S | McGee | Bassitt | R |
| 8/13/2021 | | @ | Mia | L | 1-2 | | Wood,A | L | Hendriks | | Yarbrough | L |
| 8/14/2021 | | @ | Mia | L | 2-7 | | McKay | L | McKay | | Rodriguez,E | L |
| 8/15/2021 | | @ | Mia | L | 5-9 | | Kittredge | R | Kittredge | | Maeda | R |
| 8/16/2021 | | @ | Cin | W | 3-2 | | Keuchel | L | Keuchel | Hendriks | Davies | R |
| 8/17/2021 | | @ | Cin | W | 11-5 | | Minor | L | Minor | | Green,J | R |
| 8/18/2021 | | @ | Cin | W | 5-3 | | Wood,A | L | Wood,A | Hendriks | Gallen | R |
| 8/20/2021 | | | KC | W | 4-3 | | Kittredge | R | Kittredge | McGee | Velazquez,H | R |
| 8/21/2021 | | | KC | L | 1-2 | 10 | Keuchel | L | Martin,Ch | | Wheeler | R |
| 8/22/2021 | | | KC | W | 6-5 | | Minor | L | Martin,Ch | | Stroman | R |
| 8/23/2021 | | | Col | L | 4-8 | | Barlow,S | R | Barlow,S | | Mikolas | R |
| 8/24/2021 | | | Col | L | 1-7 | | Martin,Ch | R | Martin,Ch | | Foltynewicz | R |
| 8/25/2021 | | | Col | L | 4-5 | | Kittredge | R | Barlow,S | | Garcia,D | R |
| 8/27/2021 | | @ | ChA | L | 0-2 | | Keuchel | L | Keuchel | | Mize | R |
| 8/28/2021 | | @ | ChA | L | 0-5 | | Minor | L | Minor | | Seabold | R |
| 8/29/2021 | | @ | ChA | L | 3-5 | | Wood,A | L | Wood,A | | White,Mit | R |
| 8/31/2021 | | @ | Min | W | 9-1 | | Kittredge | R | Kittredge | | Thornton | R |
| 9/1/2021 | | @ | Min | L | 4-7 | | Keuchel | L | Keuchel | | Ober | R |
| 9/2/2021 | | | Pit | W | 4-2 | | Minor | L | Minor | Hendriks | Archer | R |
| 9/3/2021 | | | Pit | L | 1-2 | | Wood,A | L | Green,C | | Boyd | L |
| 9/4/2021 | | | Pit | W | 7-4 | | Montas | R | McGee | Hendriks | Wainwright | R |
| 9/5/2021 | | | Pit | L | 8-9 | 10 | McKay | L | Martin,Ch | | Hill,R | L |
| 9/6/2021 | | | Cin | W | 4-2 | | Keuchel | L | Keuchel | Kittredge | Jefferies | R |
| 9/7/2021 | | | Cin | W | 5-3 | | Minor | L | Minor | Barlow,S | Lindblom | R |
| 9/8/2021 | | | Cin | L | 0-1 | | Wood,A | L | Wood,A | | Hardy | L |
| 9/10/2021 | | | SF | W | 4-2 | | James,J | R | Fairbanks | Hendriks | Taylor,Bl | L |
| 9/11/2021 | | | SF | W | 9-8 | | Keuchel | L | Wick | | Hjelle | R |
| 9/12/2021 | | | SF | W | 4-2 | | Minor | L | Minor | Hendriks | Canning,Gr | R |
| 9/14/2021 | | @ | Phi | L | 1-2 | | Green,C | R | Barlow,S | | Nola,Aa | R |
| 9/15/2021 | | @ | Phi | W | 2-1 | 10 | Kittredge | R | Hendriks | | Morton | R |
| 9/16/2021 | | @ | Phi | L | 1-5 | | Keuchel | L | Keuchel | | Heaney | L |
| 9/17/2021 | | @ | Mil | L | 4-5 | 10 | Minor | L | James,J | | Woods Richardsn | R |
| 9/18/2021 | | @ | Mil | W | 6-3 | | Wood,A | L | Wood,A | McGee | Manaea | L |
| 9/19/2021 | | @ | Mil | W | 7-2 | | Green,C | R | Barlow,S | Fairbanks | Clarke | R |
| 9/21/2021 | | | Min | L | 3-5 | | Kittredge | R | Kittredge | | Civale | R |
| 9/22/2021 | | | Min | W | 6-4 | | Keuchel | L | Hendriks | Wick | Quantrill | R |
| 9/24/2021 | | | StL | L | 3-12 | | Wood,A | L | Wood,A | | Ponce de Leon | R |
| 9/25/2021 | | | StL | W | 6-5 | 10 | Green,C | R | Hendriks | | Wilson,Bry | R |
| 9/26/2021 | | | StL | L | 5-7 | | Kittredge | R | Kittredge | | Muller | L |
| 9/28/2021 | | @ | Pit | W | 3-2 | | Keuchel | L | Keuchel | Hendriks | Schmidt | R |
| 9/29/2021 | | @ | Pit | L | 3-4 | | Wood,A | L | Wood,A | | Kowar | R |
| 9/30/2021 | | @ | Pit | W | 7-2 | | Green,C | R | Green,C | | Wainwright | R |
| 10/1/2021 | | @ | StL | L | 0-5 | | Montas | R | Montas | | Wilson,Bry | R |
| 10/2/2021 | | @ | StL | L | 1-2 | | Keuchel | L | Keuchel | | Fernandez,J | R |
| 10/3/2021 | | @ | StL | W | 3-2 | | Green,C | R | Fairbanks | Hendriks | Martin,Co | R |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/1/2021 | | | Pit | L | | 1 | 2 | 0 | 1 | .000 | 0-1 | L1 | 1 |
| 4/3/2021 | | | Pit | L | | 5 | 7 | 0 | 2 | .000 | 0-2 | L2 | 2 |
| 4/4/2021 | | | Pit | W | Ward | 6 | 5 | 1 | 2 | .333 | 1-2 | W1 | 3 |
| 4/5/2021 | | | Mil | L | | 2 | 3 | 1 | 3 | .250 | 1-3 | L1 | 4 |
| 4/6/2021 | | | Mil | L | | 5 | 9 | 1 | 4 | .200 | 1-4 | L2 | 5 |
| 4/7/2021 | | | Mil | W | Taylor,Ch | 8 | 3 | 2 | 4 | .333 | 2-4 | W1 | 6 |
| 4/8/2021 | | @ | Pit | L | | 2 | 10 | 2 | 5 | .286 | 2-5 | L1 | 7 |
| 4/10/2021 | | @ | Pit | W | Dickerson,A | 4 | 1 | 3 | 5 | .375 | 3-5 | W1 | 8 |
| 4/11/2021 | | @ | Pit | L | | 0 | 1 | 3 | 6 | .333 | 3-6 | L1 | 9 |
| 4/12/2021 | | @ | Mil | W | Brosseau | 8 | 1 | 4 | 6 | .400 | 4-6 | W1 | 10 |
| 4/13/2021 | | @ | Mil | W | Cabrera,A | 3 | 2 | 5 | 6 | .455 | 5-5 | W2 | 11 |
| 4/14/2021 | | @ | Mil | L | | 1 | 5 | 5 | 7 | .417 | 5-5 | L1 | 12 |
| 4/16/2021 | | | Atl | W | White,T | 7 | 1 | 6 | 7 | .462 | 5-5 | W1 | 13 |
| 4/17/2021 | | | Atl | W | | 4 | 1 | 7 | 7 | .500 | 6-4 | W2 | 14 |
| 4/18/2021 | | | Atl | W | Cooper | 6 | 5 | 8 | 7 | .533 | 7-3 | W3 | 15 |
| 4/20/2021 | | | NYN | W | Brosseau | 12 | 1 | 9 | 7 | .563 | 7-3 | W4 | 16 |
| 4/21/2021 | | | NYN | L | | 0 | 5 | 9 | 8 | .529 | 7-3 | L1 | 17 |
| 4/22/2021 | | | NYN | L | | 3 | 4 | 9 | 9 | .500 | 6-4 | L2 | 18 |
| 4/23/2021 | | | Mil | W | Taylor,Ch | 6 | 4 | 10 | 9 | .526 | 7-3 | W1 | 19 |
| 4/24/2021 | | | Mil | L | | 1 | 3 | 10 | 10 | .500 | 6-4 | L1 | 20 |
| 4/25/2021 | | | Mil | W | Pederson | 9 | 7 | 11 | 10 | .524 | 6-4 | W1 | 21 |
| 4/26/2021 | | @ | Atl | L | | 5 | 6 | 11 | 11 | .500 | 6-4 | L1 | 22 |
| 4/27/2021 | | @ | Atl | L | | 2 | 3 | 11 | 12 | .478 | 5-5 | L2 | 23 |
| 4/28/2021 | | @ | Atl | W | Brosseau | 6 | 5 | 12 | 12 | .500 | 5-5 | W1 | 24 |
| 4/29/2021 | | @ | Atl | L | | 2 | 3 | 12 | 13 | .480 | 4-6 | L1 | 25 |
| 4/30/2021 | | @ | Cin | W | Cabrera,A | 12 | 4 | 13 | 13 | .500 | 4-6 | W1 | 26 |
| 5/1/2021 | | @ | Cin | L | | 0 | 5 | 13 | 14 | .481 | 4-6 | L1 | 27 |
| 5/2/2021 | | @ | Cin | L | | 0 | 1 | 13 | 15 | .464 | 4-6 | L2 | 28 |
| 5/3/2021 | | | LAN | W | Cabrera,A | 6 | 5 | 14 | 15 | .483 | 4-6 | W1 | 29 |
| 5/4/2021 | | | LAN | W | | 6 | 3 | 15 | 15 | .500 | 5-5 | W2 | 30 |
| 5/5/2021 | | | LAN | L | | 1 | 3 | 15 | 16 | .484 | 4-6 | L1 | 31 |
| 5/7/2021 | | | Pit | L | | 2 | 5 | 15 | 17 | .469 | 4-6 | L2 | 32 |
| 5/8/2021 | | | Pit | W | Brosseau | 12 | 1 | 16 | 17 | .485 | 5-5 | W1 | 33 |
| 5/9/2021 | | | Pit | L | | 3 | 6 | 16 | 18 | .471 | 4-6 | L1 | 34 |
| 5/11/2021 | | @ | Cle | L | | 3 | 4 | 16 | 19 | .457 | 4-6 | L2 | 35 |
| 5/12/2021 | | @ | Cle | L | | 3 | 4 | 16 | 20 | .444 | 3-7 | L3 | 36 |
| 5/14/2021 | | @ | Det | L | | 1 | 2 | 16 | 21 | .432 | 3-7 | L4 | 37 |
| 5/15/2021 | | @ | Det | W | Cooper | 7 | 4 | 17 | 21 | .447 | 4-6 | W1 | 38 |
| 5/16/2021 | | @ | Det | L | | 2 | 3 | 17 | 22 | .436 | 3-7 | L1 | 39 |
| 5/17/2021 | | | Was | L | | 2 | 4 | 17 | 23 | .425 | 2-8 | L2 | 40 |
| 5/18/2021 | | | Was | W | Taylor,Ch | 6 | 3 | 18 | 23 | .439 | 3-7 | W1 | 41 |
| 5/19/2021 | | | Was | W | | 8 | 1 | 19 | 23 | .452 | 4-6 | W2 | 42 |
| 5/20/2021 | | | Was | W | | 6 | 4 | 20 | 23 | .465 | 4-6 | W3 | 43 |
| 5/21/2021 | | @ | StL | L | | 3 | 4 | 20 | 24 | .455 | 4-6 | L1 | 44 |
| 5/22/2021 | | @ | StL | L | | 2 | 3 | 20 | 25 | .444 | 4-6 | L2 | 45 |
| 5/23/2021 | | @ | StL | W | Simmons | 7 | 1 | 21 | 25 | .457 | 5-5 | W1 | 46 |
| 5/25/2021 | | @ | Pit | L | | 3 | 8 | 21 | 26 | .447 | 5-5 | L1 | 47 |
| 5/26/2021 | | @ | Pit | W | Taylor,Ch | 7 | 0 | 22 | 26 | .458 | 5-5 | W1 | 48 |
| 5/27/2021 | | @ | Pit | W | Simmons | 4 | 3 | 23 | 26 | .469 | 6-4 | W2 | 49 |
| 5/28/2021 | | | Cin | L | | 2 | 5 | 23 | 27 | .460 | 6-4 | L1 | 50 |
| 5/29/2021 | | | Cin | W | Dickerson,A | 7 | 2 | 24 | 27 | .471 | 6-4 | W1 | 51 |
| 5/30/2021 | | | Cin | L | | 3 | 9 | 24 | 28 | .462 | 5-5 | L1 | 52 |
| 5/31/2021 | | | SD | W | Brosseau | 5 | 0 | 25 | 28 | .472 | 5-5 | W1 | 53 |
| 6/1/2021 | | | SD | L | | 2 | 4 | 25 | 29 | .463 | 5-5 | L1 | 54 |
| 6/2/2021 | | | SD | L | | 5 | 6 | 25 | 30 | .455 | 5-5 | L2 | 55 |
| 6/3/2021 | | @ | SF | W | Pederson | 3 | 1 | 26 | 30 | .464 | 5-5 | W1 | 56 |
| 6/4/2021 | | @ | SF | W | Contreras,WE | 1 | 0 | 27 | 30 | .474 | 6-4 | W2 | 57 |
| 6/5/2021 | | @ | SF | W | Calhoun,W | 4 | 2 | 28 | 30 | .483 | 6-4 | W3 | 58 |
| 6/6/2021 | | @ | SF | W | Dickerson,A | 8 | 7 | 29 | 30 | .492 | 6-4 | W4 | 59 |
| 6/7/2021 | | @ | SD | W | | 7 | 4 | 30 | 30 | .500 | 7-3 | W5 | 60 |
| 6/8/2021 | | @ | SD | L | | 1 | 5 | 30 | 31 | .492 | 6-4 | L1 | 61 |
| 6/9/2021 | | @ | SD | L | | 2 | 6 | 30 | 32 | .484 | 6-4 | L2 | 62 |
| 6/11/2021 | | | StL | L | | 1 | 2 | 30 | 33 | .476 | 5-5 | L3 | 63 |
| 6/12/2021 | | | StL | W | Taylor,Ch | 3 | 1 | 31 | 33 | .484 | 6-4 | W1 | 64 |
| 6/13/2021 | | | StL | L | | 0 | 4 | 31 | 34 | .477 | 6-4 | L1 | 65 |
| 6/14/2021 | | @ | NYN | W | Davis,K | 3 | 1 | 32 | 34 | .485 | 6-4 | W1 | 66 |
| 6/15/2021 | | @ | NYN | L | | 4 | 6 | 32 | 35 | .478 | 5-5 | L1 | 67 |
| 6/16/2021 | | @ | NYN | W | White,T | 7 | 4 | 33 | 35 | .485 | 5-5 | W1 | 68 |
| 6/17/2021 | | @ | NYN | L | | 1 | 2 | 33 | 36 | .478 | 4-6 | L1 | 69 |
| 6/18/2021 | | | Mia | L | | 0 | 7 | 33 | 37 | .471 | 3-7 | L2 | 70 |
| 6/19/2021 | | | Mia | W | Semien | 4 | 3 | 34 | 37 | .479 | 4-6 | W1 | 71 |
| 6/20/2021 | | | Mia | L | | 2 | 7 | 34 | 38 | .472 | 4-6 | L1 | 72 |
| 6/21/2021 | | | Cle | W | White,T | 10 | 3 | 35 | 38 | .479 | 5-5 | W1 | 73 |
| 6/22/2021 | | | Cle | L | | 5 | 6 | 35 | 39 | .473 | 4-6 | L1 | 74 |
| 6/24/2021 | | @ | LAN | W | Davis,K | 9 | 0 | 36 | 39 | .480 | 5-5 | W1 | 75 |
| 6/25/2021 | | @ | LAN | W | Semien | 3 | 0 | 37 | 39 | .487 | 5-5 | W2 | 76 |
| 6/26/2021 | | @ | LAN | L | | 6 | 7 | 37 | 40 | .481 | 5-5 | L1 | 77 |
| 6/27/2021 | | @ | LAN | L | | 1 | 2 | 37 | 41 | .474 | 4-6 | L2 | 78 |
| 6/28/2021 | | @ | Mil | W | Pederson | 5 | 2 | 38 | 41 | .481 | 5-5 | W1 | 79 |
| 6/29/2021 | | @ | Mil | W | Contreras,WE | 7 | 5 | 39 | 41 | .488 | 6-4 | W2 | 80 |
| 6/30/2021 | | @ | Mil | L | | 3 | 4 | 39 | 42 | .481 | 5-5 | L1 | 81 |
| 7/2/2021 | | @ | Cin | W | Contreras,WE | 11 | 10 | 40 | 42 | .488 | 6-4 | W1 | 82 |
| 7/3/2021 | | @ | Cin | L | | 1 | 3 | 40 | 43 | .482 | 5-5 | L1 | 83 |
| 7/4/2021 | | @ | Cin | L | | 6 | 7 | 40 | 44 | .476 | 5-5 | L2 | 84 |
| 7/5/2021 | | | Phi | W | Semien | 5 | 3 | 41 | 44 | .482 | 5-5 | W1 | 85 |
| 7/6/2021 | | | Phi | L | | 2 | 6 | 41 | 45 | .477 | 4-6 | L1 | 86 |
| 7/7/2021 | | | Phi | W | Pederson | 5 | 2 | 42 | 45 | .483 | 5-5 | W1 | 87 |
| 7/8/2021 | | | Phi | W | Brosseau | 6 | 2 | 43 | 45 | .489 | 6-4 | W2 | 88 |
| 7/9/2021 | | | StL | W | | 8 | 3 | 44 | 45 | .494 | 6-4 | W3 | 89 |
| 7/10/2021 | | | StL | W | Brosseau | 13 | 3 | 45 | 45 | .500 | 6-4 | W4 | 90 |
| 7/11/2021 | | | StL | W | White,T | 2 | 1 | 46 | 45 | .505 | 7-3 | W5 | 91 |
| 7/16/2021 | | @ | Ari | L | | 4 | 5 | 46 | 46 | .500 | 6-4 | L1 | 92 |
| 7/17/2021 | | @ | Ari | L | | 1 | 2 | 46 | 47 | .495 | 6-4 | L2 | 93 |
| 7/18/2021 | | @ | Ari | W | McNeil | 4 | 0 | 47 | 47 | .500 | 7-3 | W1 | 94 |
| 7/19/2021 | | @ | StL | L | | 9 | 10 | 47 | 48 | .495 | 6-4 | L1 | 95 |
| 7/20/2021 | | @ | StL | W | Hoerner | 10 | 4 | 48 | 48 | .500 | 7-3 | W1 | 96 |
| 7/21/2021 | | @ | StL | W | Semien | 4 | 1 | 49 | 48 | .505 | 7-3 | W2 | 97 |
| 7/22/2021 | | @ | StL | W | Cronenworth | 7 | 6 | 50 | 48 | .510 | 7-3 | W3 | 98 |
| 7/23/2021 | | | Ari | W | Ward | 6 | 1 | 51 | 48 | .515 | 7-3 | W4 | 99 |
| 7/24/2021 | | | Ari | L | | 3 | 4 | 51 | 49 | .510 | 6-4 | L1 | 100 |
| 7/25/2021 | | | Ari | L | | 3 | 5 | 51 | 50 | .505 | 5-5 | L2 | 101 |
| 7/26/2021 | | | Cin | W | Dickerson,A | 4 | 3 | 52 | 50 | .510 | 6-4 | W1 | 102 |
| 7/27/2021 | | | Cin | W | Brosseau | 7 | 4 | 53 | 50 | .515 | 7-3 | W2 | 103 |
| 7/28/2021 | | | Cin | L | | 4 | 9 | 53 | 51 | .510 | 6-4 | L1 | 104 |
| 7/29/2021 | | | Cin | W | Brosseau | 5 | 2 | 54 | 51 | .514 | 7-3 | W1 | 105 |
| 7/30/2021 | | @ | Was | W | Cronenworth | 5 | 4 | 55 | 51 | .519 | 7-3 | W2 | 106 |
| 7/31/2021 | | @ | Was | L | | 4 | 5 | 55 | 52 | .514 | 6-4 | L1 | 107 |
| 8/1/2021 | | @ | Was | L | | 1 | 3 | 55 | 53 | .509 | 5-5 | L2 | 108 |
| 8/3/2021 | | @ | Col | W | McNeil | 4 | 1 | 56 | 53 | .514 | 5-5 | W1 | 109 |
| 8/4/2021 | | @ | Col | L | | 3 | 8 | 56 | 54 | .509 | 5-5 | L1 | 110 |
| 8/5/2021 | | @ | Col | L | | 2 | 4 | 56 | 55 | .505 | 5-5 | L2 | 111 |
| 8/6/2021 | | | ChA | W | Brosseau | 3 | 2 | 57 | 55 | .509 | 5-5 | W1 | 112 |
| 8/7/2021 | | | ChA | W | Ward | 4 | 2 | 58 | 55 | .513 | 5-5 | W2 | 113 |
| 8/8/2021 | | | ChA | L | | 2 | 3 | 58 | 56 | .509 | 5-5 | L1 | 114 |
| 8/9/2021 | | | Mil | W | McNeil | 7 | 0 | 59 | 56 | .513 | 5-5 | W1 | 115 |
| 8/10/2021 | | | Mil | L | | 3 | 4 | 59 | 57 | .509 | 4-6 | L1 | 116 |
| 8/11/2021 | | | Mil | W | Cabrera,A | 11 | 2 | 60 | 57 | .513 | 5-5 | W1 | 117 |
| 8/12/2021 | | | Mil | W | Pederson | 11 | 7 | 61 | 57 | .517 | 6-4 | W2 | 118 |
| 8/13/2021 | | @ | Mia | L | | 1 | 2 | 61 | 58 | .513 | 5-5 | L1 | 119 |
| 8/14/2021 | | @ | Mia | L | | 2 | 7 | 61 | 59 | .508 | 5-5 | L2 | 120 |
| 8/15/2021 | | @ | Mia | L | | 5 | 9 | 61 | 60 | .504 | 5-5 | L3 | 121 |
| 8/16/2021 | | @ | Cin | W | Semien | 3 | 2 | 62 | 60 | .508 | 5-5 | W1 | 122 |
| 8/17/2021 | | @ | Cin | W | Brosseau | 11 | 5 | 63 | 60 | .512 | 5-5 | W2 | 123 |
| 8/18/2021 | | @ | Cin | W | Dickerson,A | 5 | 3 | 64 | 60 | .516 | 6-4 | W3 | 124 |
| 8/20/2021 | | | KC | W | Cabrera,A | 4 | 3 | 65 | 60 | .520 | 6-4 | W4 | 125 |
| 8/21/2021 | | | KC | L | | 1 | 2 | 65 | 61 | .516 | 6-4 | L1 | 126 |
| 8/22/2021 | | | KC | W | Pederson | 6 | 5 | 66 | 61 | .520 | 6-4 | W1 | 127 |
| 8/23/2021 | | | Col | L | | 4 | 8 | 66 | 62 | .516 | 5-5 | L1 | 128 |
| 8/24/2021 | | | Col | L | | 1 | 7 | 66 | 63 | .512 | 5-5 | L2 | 129 |
| 8/25/2021 | | | Col | L | | 4 | 5 | 66 | 64 | .508 | 5-5 | L3 | 130 |
| 8/27/2021 | | @ | ChA | L | | 0 | 2 | 66 | 65 | .504 | 5-5 | L4 | 131 |
| 8/28/2021 | | @ | ChA | L | | 0 | 5 | 66 | 66 | .500 | 4-6 | L5 | 132 |
| 8/29/2021 | | @ | ChA | L | | 3 | 5 | 66 | 67 | .496 | 3-7 | L6 | 133 |
| 8/31/2021 | | @ | Min | W | Davis,K | 9 | 1 | 67 | 67 | .500 | 3-7 | W1 | 134 |
| 9/1/2021 | | @ | Min | L | | 4 | 7 | 67 | 68 | .496 | 2-8 | L1 | 135 |
| 9/2/2021 | | | Pit | W | Semien | 4 | 2 | 68 | 68 | .500 | 3-7 | W1 | 136 |
| 9/3/2021 | | | Pit | L | | 1 | 2 | 68 | 69 | .496 | 2-8 | L1 | 137 |
| 9/4/2021 | | | Pit | W | Dickerson,A | 7 | 4 | 69 | 69 | .500 | 3-7 | W1 | 138 |
| 9/5/2021 | | | Pit | L | | 8 | 9 | 69 | 70 | .496 | 3-7 | L1 | 139 |
| 9/6/2021 | | | Cin | W | Davis,K | 4 | 2 | 70 | 70 | .500 | 4-6 | W1 | 140 |
| 9/7/2021 | | | Cin | W | Contreras,WE | 5 | 3 | 71 | 70 | .504 | 5-5 | W2 | 141 |
| 9/8/2021 | | | Cin | L | | 0 | 1 | 71 | 71 | .500 | 5-5 | L1 | 142 |
| 9/10/2021 | | | SF | W | Frazier,A | 4 | 2 | 72 | 71 | .503 | 6-4 | W1 | 143 |
| 9/11/2021 | | | SF | W | Taylor,Ch | 9 | 8 | 73 | 71 | .507 | 6-4 | W2 | 144 |
| 9/12/2021 | | | SF | W | Cabrera,A | 4 | 2 | 74 | 71 | .510 | 7-3 | W3 | 145 |
| 9/14/2021 | | @ | Phi | L | | 1 | 2 | 74 | 72 | .507 | 6-4 | L1 | 146 |
| 9/15/2021 | | @ | Phi | W | Brosseau | 2 | 1 | 75 | 72 | .510 | 7-3 | W1 | 147 |
| 9/16/2021 | | @ | Phi | L | | 1 | 5 | 75 | 73 | .507 | 6-4 | L1 | 148 |
| 9/17/2021 | | @ | Mil | L | | 4 | 5 | 75 | 74 | .503 | 6-4 | L2 | 149 |
| 9/18/2021 | | @ | Mil | W | Contreras,WE | 6 | 3 | 76 | 74 | .507 | 6-4 | W1 | 150 |
| 9/19/2021 | | @ | Mil | W | Cabrera,A | 7 | 2 | 77 | 74 | .510 | 6-4 | W2 | 151 |
| 9/21/2021 | | | Min | L | | 3 | 5 | 77 | 75 | .507 | 6-4 | L1 | 152 |
| 9/22/2021 | | | Min | W | Taylor,Ch | 6 | 4 | 78 | 75 | .510 | 6-4 | W1 | 153 |
| 9/24/2021 | | | StL | L | | 3 | 12 | 78 | 76 | .506 | 5-5 | L1 | 154 |
| 9/25/2021 | | | StL | W | Taylor,Ch | 6 | 5 | 79 | 76 | .510 | 5-5 | W1 | 155 |
| 9/26/2021 | | | StL | L | | 5 | 7 | 79 | 77 | .506 | 5-5 | L1 | 156 |
| 9/28/2021 | | @ | Pit | W | Cabrera,A | 3 | 2 | 80 | 77 | .510 | 5-5 | W1 | 157 |
| 9/29/2021 | | @ | Pit | L | | 3 | 4 | 80 | 78 | .506 | 5-5 | L1 | 158 |
| 9/30/2021 | | @ | Pit | W | Contreras,WE | 7 | 2 | 81 | 78 | .509 | 6-4 | W1 | 159 |
| 10/1/2021 | | @ | StL | L | | 0 | 5 | 81 | 79 | .506 | 5-5 | L1 | 160 |
| 10/2/2021 | | @ | StL | L | | 1 | 2 | 81 | 80 | .503 | 4-6 | L2 | 161 |
| 10/3/2021 | | @ | StL | W | Semien | 3 | 2 | 82 | 80 | .506 | 5-5 | W1 | 162 |
