Team game results -- 2021 Houston Astros
Regular season
| Primary |
| Date | # | | Opp | | Score | Inn | Starter | T | W/L | Save | Versus | T |
| 4/1/2021 | | @ | Oak | L | 1-4 | | Bauer | R | Bauer | | Cole,G | R |
| 4/2/2021 | | @ | Oak | L | 6-7 | | Brubaker | R | Yardley | | Bundy | R |
| 4/3/2021 | | @ | Oak | L | 2-3 | | Sanchez,R | L | Sanchez,R | | Gray,Jon | R |
| 4/4/2021 | | @ | Oak | L | 2-7 | | Ryan,J | R | Ryan,J | | Peterson,Da | L |
| 4/5/2021 | | @ | LAA | W | 9-4 | | Bauer | R | Feliz,M | Kennedy | Howard,Sp | R |
| 4/6/2021 | | @ | LAA | L | 6-14 | | Matz | L | Holland,G | | Banda | L |
| 4/8/2021 | | | Oak | W | 4-3 | 10 | Gant | R | Minter | | Gray,Jon | R |
| 4/9/2021 | | | Oak | L | 1-13 | | Brubaker | R | Venditte | | Peterson,Da | L |
| 4/10/2021 | | | Oak | L | 0-4 | | Bauer | R | Bauer | | Webb,L | R |
| 4/12/2021 | | | Det | W | 6-0 | | Matz | L | Matz | | Castillo,D | R |
| 4/13/2021 | | | Det | L | 4-5 | | Gant | R | Gant | | Giolito | R |
| 4/14/2021 | | | Det | L | 0-9 | | Brubaker | R | Brubaker | | Buehler | R |
| 4/16/2021 | | @ | Sea | W | 3-1 | | Bauer | R | Feliz,M | Minter | Duran,Jh | R |
| 4/17/2021 | | @ | Sea | W | 4-3 | | Matz | L | Bettencourt | Minter | Marquez,B | L |
| 4/18/2021 | | @ | Sea | L | 3-5 | | Gant | R | Gant | | Glasnow | R |
| 4/20/2021 | | @ | Col | W | 7-4 | 10 | Ray,R | L | Bettencourt | | Foltynewicz | R |
| 4/21/2021 | | @ | Col | L | 4-6 | | Brubaker | R | Venditte | | Sandoval,Pat | L |
| 4/22/2021 | | | LAA | W | 7-4 | | Bauer | R | Bauer | Minter | Howard,Sp | R |
| 4/23/2021 | | | LAA | W | 9-1 | | Matz | L | Matz | | Banda | L |
| 4/24/2021 | | | LAA | W | 4-3 | | Gant | R | Kennedy | Venditte | Anderson,Bre | L |
| 4/25/2021 | | | LAA | W | 11-4 | | Ray,R | L | Ray,R | | Megill | R |
| 4/26/2021 | | | Sea | W | 7-1 | | Brubaker | R | Brubaker | | McClanahan | L |
| 4/27/2021 | | | Sea | W | 10-2 | | Bauer | R | Bauer | | Duran,Jh | R |
| 4/28/2021 | | | Sea | W | 6-5 | 11 | Matz | L | Holland,G | | Marquez,B | L |
| 4/29/2021 | | | Sea | W | 7-1 | | Gant | R | Gant | | Glasnow | R |
| 4/30/2021 | | @ | Tam | W | 5-4 | | Ray,R | L | Bettencourt | | King,M | R |
| 5/1/2021 | | @ | Tam | L | 4-9 | | Brubaker | R | Bettencourt | | Smeltzer | L |
| 5/2/2021 | | @ | Tam | L | 4-5 | | Bauer | R | Bettencourt | | Anderson,I | R |
| 5/4/2021 | | @ | NYA | L | 4-5 | | Matz | L | Feliz,M | | Paddack | R |
| 5/5/2021 | | @ | NYA | L | 5-9 | | Gant | R | Gant | | Urena,J | R |
| 5/6/2021 | | @ | NYA | L | 1-4 | | Ray,R | L | Feliz,M | | Strasburg | R |
| 5/7/2021 | | | Tor | W | 6-5 | 10 | Brubaker | R | Venditte | | Corbin | L |
| 5/8/2021 | | | Tor | W | 10-1 | | Bauer | R | Bauer | | Abbott | R |
| 5/9/2021 | | | Tor | W | 7-1 | | Matz | L | Matz | | Richards,G | R |
| 5/10/2021 | | | LAA | W | 5-2 | | Gant | R | Feliz,M | Bettencourt | Montgomery,M | L |
| 5/11/2021 | | | LAA | L | 7-8 | 10 | Ray,R | L | Yardley | | Hoffman | R |
| 5/12/2021 | | | LAA | L | 7-12 | | Brubaker | R | Brubaker | | Rondon,A | R |
| 5/13/2021 | | | Tex | L | 2-4 | | Bauer | R | Bauer | | Means | L |
| 5/14/2021 | | | Tex | W | 12-6 | | Matz | L | Matz | | Medina,L | R |
| 5/15/2021 | | | Tex | W | 4-2 | | Gant | R | Gant | Minter | Ohtani | R |
| 5/16/2021 | | | Tex | L | 2-7 | | Ray,R | L | Ray,R | | Patino | R |
| 5/18/2021 | | @ | Oak | L | 0-1 | | Brubaker | R | Brubaker | | Cole,G | R |
| 5/19/2021 | | @ | Oak | L | 6-8 | | Bauer | R | Bauer | | Webb,L | R |
| 5/20/2021 | | @ | Oak | L | 3-4 | | Matz | L | Matz | | Bundy | R |
| 5/21/2021 | | @ | Tex | W | 11-6 | | Gant | R | Holland,G | | McCullers Jr. | R |
| 5/22/2021 | | @ | Tex | W | 8-7 | 10 | Ray,R | L | Sanchez,R | Vizcaino,Ar | Holloway | R |
| 5/23/2021 | | @ | Tex | L | 6-9 | | Brubaker | R | Vizcaino,Ar | | Lopez,P | R |
| 5/25/2021 | | | LAN | W | 9-8 | 11 | Bauer | R | Bettencourt | | Borucki | L |
| 5/26/2021 | | | LAN | W | 5-4 | | Matz | L | Minter | | Junis | R |
| 5/28/2021 | | | SD | W | 6-5 | | Gant | R | Holland,G | Minter | Dunning | R |
| 5/29/2021 | | | SD | W | 8-3 | | Ray,R | L | Ray,R | | Garcia,D | R |
| 5/30/2021 | | | SD | L | 2-4 | | Brubaker | R | Bettencourt | | Schmidt | R |
| 5/31/2021 | | | Bos | L | 3-5 | | Bauer | R | Bauer | | Castillo,L | R |
| 6/1/2021 | | | Bos | L | 3-6 | | Matz | L | Minter | | Marquez,G | R |
| 6/2/2021 | | | Bos | L | 2-6 | | Gant | R | Gant | | Rasmussen | R |
| 6/3/2021 | | | Bos | W | 7-0 | | Ray,R | L | Ray,R | | Woodruff | R |
| 6/4/2021 | | @ | Tor | W | 11-6 | | Brubaker | R | Minter | | Corbin | L |
| 6/5/2021 | | @ | Tor | L | 4-8 | | Bauer | R | Bauer | | Abbott | R |
| 6/6/2021 | | @ | Tor | W | 8-5 | | Gonzalez,V | L | Holland,G | | Richards,G | R |
| 6/8/2021 | | @ | Bos | L | 0-1 | | Gant | R | Kennedy | | Woodruff | R |
| 6/9/2021 | | @ | Bos | L | 2-4 | | Ray,R | L | Ray,R | | Castillo,L | R |
| 6/10/2021 | | @ | Bos | W | 6-3 | | Brubaker | R | Brubaker | Minter | Marquez,G | R |
| 6/11/2021 | | @ | Min | W | 5-1 | | Bauer | R | Bauer | Pressly | Civale | R |
| 6/12/2021 | | @ | Min | W | 4-3 | | Rogers,Tr | L | Rogers,Tr | Pressly | Ober | R |
| 6/13/2021 | | @ | Min | W | 6-3 | 11 | Gant | R | Pressly | Bettencourt | Arrieta | R |
| 6/15/2021 | | | Tex | W | 3-0 | | Ray,R | L | Ray,R | Kennedy | Ohtani | R |
| 6/16/2021 | | | Tex | L | 4-5 | | Pineda,M | R | Minter | | Reyes,A | R |
| 6/17/2021 | | | ChA | L | 3-17 | | Bauer | R | Bauer | | Seabold | R |
| 6/18/2021 | | | ChA | W | 7-6 | | Rogers,Tr | L | Rogers,Tr | Brubaker | Flores,B | L |
| 6/19/2021 | | | ChA | W | 8-5 | | Gant | R | Gant | Minter | de la Cruz,J | R |
| 6/20/2021 | | | ChA | W | 6-3 | | Ray,R | L | Ray,R | Holland,G | Megill | R |
| 6/21/2021 | | @ | Bal | W | 6-5 | | Pineda,M | R | Minter | Holland,G | Snell | L |
| 6/22/2021 | | @ | Bal | W | 12-8 | | Bauer | R | Brubaker | | Taillon | R |
| 6/23/2021 | | @ | Bal | L | 7-10 | | Rogers,Tr | L | Brubaker | | Sanchez,Aa | R |
| 6/24/2021 | | @ | Det | L | 2-5 | | Gant | R | Minter | | Giolito | R |
| 6/25/2021 | | @ | Det | W | 11-8 | | Ray,R | L | Ray,R | Pressly | Buehler | R |
| 6/26/2021 | | @ | Det | L | 1-4 | | Pineda,M | R | Pineda,M | | Berrios | R |
| 6/27/2021 | | @ | Det | W | 3-2 | | Bauer | R | Bettencourt | Pressly | Buehler | R |
| 6/28/2021 | | | Bal | L | 4-5 | | Rogers,Tr | L | Bettencourt | | deGrom | R |
| 6/29/2021 | | | Bal | W | 6-5 | 10 | Gant | R | Kennedy | | Snell | L |
| 6/30/2021 | | | Bal | W | 5-4 | | Ray,R | L | Pressly | | Taillon | R |
| 7/1/2021 | | @ | Cle | W | 4-0 | | Brubaker | R | Bettencourt | Kennedy | Kuhl | R |
| 7/2/2021 | | @ | Cle | L | 4-6 | | Bauer | R | Bauer | | Valdez,F | L |
| 7/3/2021 | | @ | Cle | W | 7-2 | | Rogers,Tr | L | Rogers,Tr | | Montgomery,J | L |
| 7/4/2021 | | @ | Cle | L | 5-6 | 10 | Gant | R | Pressly | | Wacha | R |
| 7/6/2021 | | | Oak | W | 12-3 | | Ray,R | L | Ray,R | | Cole,G | R |
| 7/7/2021 | | | Oak | W | 7-6 | 11 | Brubaker | R | Pressly | | Gray,Jon | R |
| 7/8/2021 | | | Oak | L | 1-8 | | Bauer | R | Bauer | | Eovaldi | R |
| 7/9/2021 | | | NYA | L | 8-9 | | Rogers,Tr | L | Bettencourt | | Urena,J | R |
| 7/10/2021 | | | NYA | L | 3-6 | | Gant | R | Gant | | Darvish | R |
| 7/11/2021 | | | NYA | W | 6-4 | | Ray,R | L | Bettencourt | | Scherzer | R |
| 7/16/2021 | | @ | ChA | L | 5-7 | | Brubaker | R | Brubaker | | White,Mit | R |
| 7/17/2021 | | @ | ChA | W | 6-5 | 11 | Bettencourt | R | Pressly | | Lambert,J | R |
| 7/18/2021 | | @ | ChA | W | 6-1 | | Rogers,Tr | L | Rogers,Tr | | Megill | R |
| 7/19/2021 | | | Cle | W | 4-3 | 10 | Pineda,M | R | Bettencourt | | Weaver | R |
| 7/20/2021 | | | Cle | W | 6-3 | | Ray,R | L | Ray,R | Kennedy | Kuhl | R |
| 7/21/2021 | | | Cle | L | 6-9 | | Brubaker | R | Brubaker | | Valdez,F | L |
| 7/23/2021 | | | Tex | W | 6-4 | | Rogers,Tr | L | Kennedy | Pressly | Abreu,B | R |
| 7/24/2021 | | | Tex | W | 9-4 | | Gant | R | Gant | | Toussaint | R |
| 7/25/2021 | | | Tex | W | 18-6 | | Pineda,M | R | Gonzalez,V | | Patino | R |
| 7/26/2021 | | @ | Sea | W | 7-1 | | Ray,R | L | Ray,R | | McClanahan | L |
| 7/27/2021 | | @ | Sea | W | 2-0 | | Brubaker | R | Brubaker | Trivino | Alzolay | R |
| 7/28/2021 | | @ | Sea | L | 1-4 | | Hendricks | R | Matz | | Smith,KevinP | L |
| 7/30/2021 | | @ | SF | L | 5-6 | | Gant | R | Gant | | Canning,Gr | R |
| 7/31/2021 | | @ | SF | W | 7-3 | | Pineda,M | R | Trivino | | Luzardo | L |
| 8/1/2021 | | @ | SF | W | 8-3 | | Ray,R | L | Ray,R | | Romero,S | L |
| 8/3/2021 | | @ | LAN | L | 0-4 | | Rogers,Tr | L | Rogers,Tr | | Borucki | L |
| 8/4/2021 | | @ | LAN | L | 2-3 | | Hendricks | R | Trivino | | Junis | R |
| 8/5/2021 | | | Min | W | 19-8 | | Pineda,M | R | Gant | | Arrieta | R |
| 8/6/2021 | | | Min | W | 8-0 | | Ray,R | L | Pressly | | Manning | R |
| 8/7/2021 | | | Min | L | 5-18 | | Brubaker | R | Brubaker | | Gutierrez,V | R |
| 8/8/2021 | | | Min | W | 6-1 | | Rogers,Tr | L | Rogers,Tr | | Thornton | R |
| 8/10/2021 | | | Col | W | 10-4 | | Hendricks | R | Hendricks | | Sims,L | R |
| 8/11/2021 | | | Col | W | 5-1 | | Pineda,M | R | Holland,G | | Gray,S | R |
| 8/13/2021 | | @ | LAA | W | 6-2 | 10 | Ray,R | L | Trivino | | Banda | L |
| 8/14/2021 | | @ | LAA | W | 7-5 | | Brubaker | R | Holland,G | Gonzalez,V | Naughton,P | L |
| 8/15/2021 | | @ | LAA | W | 12-1 | | Rogers,Tr | L | Rogers,Tr | | Anderson,Bre | L |
| 8/16/2021 | | @ | KC | W | 11-9 | | Hendricks | R | Gonzalez,V | Trivino | Wheeler | R |
| 8/17/2021 | | @ | KC | W | 6-3 | | Matz | L | Matz | Holland,G | Stroman | R |
| 8/18/2021 | | @ | KC | L | 1-2 | | Ray,R | L | Ray,R | | Lopez,Jo | R |
| 8/19/2021 | | @ | KC | L | 4-5 | | Brubaker | R | Trivino | | Montgomery,J | L |
| 8/20/2021 | | | Sea | W | 17-4 | | Rogers,Tr | L | Gant | | Garcia,LuisH | R |
| 8/21/2021 | | | Sea | W | 8-4 | | Hendricks | R | Hendricks | | Ynoa,H | R |
| 8/22/2021 | | | Sea | W | 8-0 | | Matz | L | Matz | | Abreu,B | R |
| 8/23/2021 | | | KC | L | 7-13 | | Ray,R | L | Ray,R | | Lopez,Jo | R |
| 8/24/2021 | | | KC | W | 9-3 | | Brubaker | R | Brubaker | | Montgomery,J | L |
| 8/25/2021 | | | KC | W | 8-6 | | Rogers,Tr | L | Rogers,Tr | | Velazquez,H | R |
| 8/27/2021 | | @ | Tex | W | 11-8 | | Hendricks | R | Brebbia | | Means | L |
| 8/28/2021 | | @ | Tex | W | 9-8 | 11 | Matz | L | Trivino | Crick | Reyes,A | R |
| 8/29/2021 | | @ | Tex | W | 6-3 | | Ray,R | L | Ray,R | Cishek | Medina,L | R |
| 8/30/2021 | | @ | Sea | W | 4-3 | | Brubaker | R | Brubaker | Holland,G | McClanahan | L |
| 8/31/2021 | | @ | Sea | L | 4-7 | | Rogers,Tr | L | Rogers,Tr | | Garcia,LuisH | R |
| 9/1/2021 | | @ | Sea | W | 19-2 | | Hendricks | R | Hendricks | | Ynoa,H | R |
| 9/3/2021 | | @ | SD | W | 7-5 | 10 | Matz | L | Brebbia | Pressly | Eflin | R |
| 9/4/2021 | | @ | SD | W | 4-3 | | Ray,R | L | Gant | Pressly | Cessa | R |
| 9/5/2021 | | @ | SD | L | 4-11 | | Brubaker | R | Brubaker | | Freeland | L |
| 9/6/2021 | | | Sea | W | 16-0 | | Rogers,Tr | L | Rogers,Tr | | Garcia,LuisH | R |
| 9/7/2021 | | | Sea | W | 6-0 | | Hendricks | R | Hendricks | | Ynoa,H | R |
| 9/8/2021 | | | Sea | W | 6-3 | | Matz | L | Matz | Pressly | Abreu,B | R |
| 9/10/2021 | | | LAA | L | 3-4 | | Ray,R | L | Trivino | | Rondon,A | R |
| 9/11/2021 | | | LAA | L | 1-7 | | Brubaker | R | Brubaker | | Howard,Sp | R |
| 9/12/2021 | | | LAA | L | 2-5 | | Rogers,Tr | L | Rogers,Tr | | Banda | L |
| 9/13/2021 | | @ | Tex | W | 5-4 | | Hendricks | R | Trivino | Pressly | Mills,A | R |
| 9/14/2021 | | @ | Tex | W | 9-4 | | Matz | L | Brebbia | | Fedde | R |
| 9/15/2021 | | @ | Tex | W | 19-8 | | Ray,R | L | Ray,R | | Patino | R |
| 9/16/2021 | | @ | Tex | W | 10-2 | | Pineda,M | R | Pineda,M | | McCullers Jr. | R |
| 9/17/2021 | | | Ari | L | 5-6 | | Rogers,Tr | L | Kennedy | | Mahle | R |
| 9/18/2021 | | | Ari | L | 0-6 | | Hendricks | R | Hendricks | | Burnes | R |
| 9/19/2021 | | | Ari | L | 6-7 | | Matz | L | Matz | | Lamet | R |
| 9/20/2021 | | @ | LAA | W | 3-2 | | Ray,R | L | Trivino | Pressly | Anderson,Bre | L |
| 9/21/2021 | | @ | LAA | L | 1-9 | | Pineda,M | R | Pineda,M | | Rondon,A | R |
| 9/22/2021 | | @ | LAA | L | 2-8 | | Rogers,Tr | L | Rogers,Tr | | Howard,Sp | R |
| 9/23/2021 | | @ | LAA | L | 2-3 | 10 | Hendricks | R | Pressly | | Banda | L |
| 9/24/2021 | | @ | Oak | L | 1-10 | | German | R | German | | Cole,G | R |
| 9/25/2021 | | @ | Oak | W | 4-0 | | Ray,R | L | Ray,R | Trivino | Webb,L | R |
| 9/26/2021 | | @ | Oak | W | 4-3 | | Pineda,M | R | Pineda,M | Crick | Eovaldi | R |
| 9/28/2021 | | | Tam | L | 4-10 | | Rogers,Tr | L | Rogers,Tr | | Green,J | R |
| 9/29/2021 | | | Tam | W | 4-3 | | Hendricks | R | Hendricks | Gant | Sheffield,Ju | L |
| 9/30/2021 | | | Tam | W | 2-1 | | German | R | German | Holland,G | Lynch | L |
| 10/1/2021 | | | Oak | L | 3-6 | | Gant | R | Brebbia | | Webb,L | R |
| 10/2/2021 | | | Oak | W | 7-5 | | Pineda,M | R | Pineda,M | Trivino | Eovaldi | R |
| 10/3/2021 | | | Oak | L | 9-10 | | Rogers,Tr | L | Rogers,Tr | | Gray,Jon | R |
| Other |
| | | | | | | | | Cumulative |
| Date | # | | Opp | | GWRBI | RF | RA | W | L | Pct | Last10 | Strk | Gm# |
| 4/1/2021 | | @ | Oak | L | | 1 | 4 | 0 | 1 | .000 | 0-1 | L1 | 1 |
| 4/2/2021 | | @ | Oak | L | | 6 | 7 | 0 | 2 | .000 | 0-2 | L2 | 2 |
| 4/3/2021 | | @ | Oak | L | | 2 | 3 | 0 | 3 | .000 | 0-3 | L3 | 3 |
| 4/4/2021 | | @ | Oak | L | | 2 | 7 | 0 | 4 | .000 | 0-4 | L4 | 4 |
| 4/5/2021 | | @ | LAA | W | Hilliard | 9 | 4 | 1 | 4 | .200 | 1-4 | W1 | 5 |
| 4/6/2021 | | @ | LAA | L | | 6 | 14 | 1 | 5 | .167 | 1-5 | L1 | 6 |
| 4/8/2021 | | | Oak | W | | 4 | 3 | 2 | 5 | .286 | 2-5 | W1 | 7 |
| 4/9/2021 | | | Oak | L | | 1 | 13 | 2 | 6 | .250 | 2-6 | L1 | 8 |
| 4/10/2021 | | | Oak | L | | 0 | 4 | 2 | 7 | .222 | 2-7 | L2 | 9 |
| 4/12/2021 | | | Det | W | Hilliard | 6 | 0 | 3 | 7 | .300 | 3-7 | W1 | 10 |
| 4/13/2021 | | | Det | L | | 4 | 5 | 3 | 8 | .273 | 3-7 | L1 | 11 |
| 4/14/2021 | | | Det | L | | 0 | 9 | 3 | 9 | .250 | 3-7 | L2 | 12 |
| 4/16/2021 | | @ | Sea | W | Soto,J | 3 | 1 | 4 | 9 | .308 | 4-6 | W1 | 13 |
| 4/17/2021 | | @ | Sea | W | Sanchez,G | 4 | 3 | 5 | 9 | .357 | 5-5 | W2 | 14 |
| 4/18/2021 | | @ | Sea | L | | 3 | 5 | 5 | 10 | .333 | 4-6 | L1 | 15 |
| 4/20/2021 | | @ | Col | W | Soler | 7 | 4 | 6 | 10 | .375 | 5-5 | W1 | 16 |
| 4/21/2021 | | @ | Col | L | | 4 | 6 | 6 | 11 | .353 | 4-6 | L1 | 17 |
| 4/22/2021 | | | LAA | W | Sano | 7 | 4 | 7 | 11 | .389 | 5-5 | W1 | 18 |
| 4/23/2021 | | | LAA | W | Polanco,J | 9 | 1 | 8 | 11 | .421 | 6-4 | W2 | 19 |
| 4/24/2021 | | | LAA | W | | 4 | 3 | 9 | 11 | .450 | 6-4 | W3 | 20 |
| 4/25/2021 | | | LAA | W | Soler | 11 | 4 | 10 | 11 | .476 | 7-3 | W4 | 21 |
| 4/26/2021 | | | Sea | W | Soto,J | 7 | 1 | 11 | 11 | .500 | 8-2 | W5 | 22 |
| 4/27/2021 | | | Sea | W | Soler | 10 | 2 | 12 | 11 | .522 | 8-2 | W6 | 23 |
| 4/28/2021 | | | Sea | W | Blackmon | 6 | 5 | 13 | 11 | .542 | 8-2 | W7 | 24 |
| 4/29/2021 | | | Sea | W | Polanco,J | 7 | 1 | 14 | 11 | .560 | 9-1 | W8 | 25 |
| 4/30/2021 | | @ | Tam | W | Sanchez,G | 5 | 4 | 15 | 11 | .577 | 9-1 | W9 | 26 |
| 5/1/2021 | | @ | Tam | L | | 4 | 9 | 15 | 12 | .556 | 9-1 | L1 | 27 |
| 5/2/2021 | | @ | Tam | L | | 4 | 5 | 15 | 13 | .536 | 8-2 | L2 | 28 |
| 5/4/2021 | | @ | NYA | L | | 4 | 5 | 15 | 14 | .517 | 7-3 | L3 | 29 |
| 5/5/2021 | | @ | NYA | L | | 5 | 9 | 15 | 15 | .500 | 6-4 | L4 | 30 |
| 5/6/2021 | | @ | NYA | L | | 1 | 4 | 15 | 16 | .484 | 5-5 | L5 | 31 |
| 5/7/2021 | | | Tor | W | Polanco,J | 6 | 5 | 16 | 16 | .500 | 5-5 | W1 | 32 |
| 5/8/2021 | | | Tor | W | Sanchez,G | 10 | 1 | 17 | 16 | .515 | 5-5 | W2 | 33 |
| 5/9/2021 | | | Tor | W | McKinney,B | 7 | 1 | 18 | 16 | .529 | 5-5 | W3 | 34 |
| 5/10/2021 | | | LAA | W | Fletcher,D | 5 | 2 | 19 | 16 | .543 | 5-5 | W4 | 35 |
| 5/11/2021 | | | LAA | L | | 7 | 8 | 19 | 17 | .528 | 4-6 | L1 | 36 |
| 5/12/2021 | | | LAA | L | | 7 | 12 | 19 | 18 | .514 | 4-6 | L2 | 37 |
| 5/13/2021 | | | Tex | L | | 2 | 4 | 19 | 19 | .500 | 4-6 | L3 | 38 |
| 5/14/2021 | | | Tex | W | Soler | 12 | 6 | 20 | 19 | .513 | 5-5 | W1 | 39 |
| 5/15/2021 | | | Tex | W | Soto,J | 4 | 2 | 21 | 19 | .525 | 6-4 | W2 | 40 |
| 5/16/2021 | | | Tex | L | | 2 | 7 | 21 | 20 | .512 | 6-4 | L1 | 41 |
| 5/18/2021 | | @ | Oak | L | | 0 | 1 | 21 | 21 | .500 | 5-5 | L2 | 42 |
| 5/19/2021 | | @ | Oak | L | | 6 | 8 | 21 | 22 | .488 | 4-6 | L3 | 43 |
| 5/20/2021 | | @ | Oak | L | | 3 | 4 | 21 | 23 | .477 | 3-7 | L4 | 44 |
| 5/21/2021 | | @ | Tex | W | Blackmon | 11 | 6 | 22 | 23 | .489 | 3-7 | W1 | 45 |
| 5/22/2021 | | @ | Tex | W | Soler | 8 | 7 | 23 | 23 | .500 | 4-6 | W2 | 46 |
| 5/23/2021 | | @ | Tex | L | | 6 | 9 | 23 | 24 | .489 | 4-6 | L1 | 47 |
| 5/25/2021 | | | LAN | W | Polanco,J | 9 | 8 | 24 | 24 | .500 | 5-5 | W1 | 48 |
| 5/26/2021 | | | LAN | W | Raleigh | 5 | 4 | 25 | 24 | .510 | 5-5 | W2 | 49 |
| 5/28/2021 | | | SD | W | Castro,S | 6 | 5 | 26 | 24 | .520 | 5-5 | W3 | 50 |
| 5/29/2021 | | | SD | W | Soto,J | 8 | 3 | 27 | 24 | .529 | 6-4 | W4 | 51 |
| 5/30/2021 | | | SD | L | | 2 | 4 | 27 | 25 | .519 | 6-4 | L1 | 52 |
| 5/31/2021 | | | Bos | L | | 3 | 5 | 27 | 26 | .509 | 6-4 | L2 | 53 |
| 6/1/2021 | | | Bos | L | | 3 | 6 | 27 | 27 | .500 | 6-4 | L3 | 54 |
| 6/2/2021 | | | Bos | L | | 2 | 6 | 27 | 28 | .491 | 5-5 | L4 | 55 |
| 6/3/2021 | | | Bos | W | Sanchez,G | 7 | 0 | 28 | 28 | .500 | 5-5 | W1 | 56 |
| 6/4/2021 | | @ | Tor | W | Sano | 11 | 6 | 29 | 28 | .509 | 6-4 | W2 | 57 |
| 6/5/2021 | | @ | Tor | L | | 4 | 8 | 29 | 29 | .500 | 5-5 | L1 | 58 |
| 6/6/2021 | | @ | Tor | W | Sano | 8 | 5 | 30 | 29 | .508 | 5-5 | W1 | 59 |
| 6/8/2021 | | @ | Bos | L | | 0 | 1 | 30 | 30 | .500 | 4-6 | L1 | 60 |
| 6/9/2021 | | @ | Bos | L | | 2 | 4 | 30 | 31 | .492 | 3-7 | L2 | 61 |
| 6/10/2021 | | @ | Bos | W | Sano | 6 | 3 | 31 | 31 | .500 | 4-6 | W1 | 62 |
| 6/11/2021 | | @ | Min | W | Soler | 5 | 1 | 32 | 31 | .508 | 5-5 | W2 | 63 |
| 6/12/2021 | | @ | Min | W | Soler | 4 | 3 | 33 | 31 | .516 | 6-4 | W3 | 64 |
| 6/13/2021 | | @ | Min | W | Sanchez,G | 6 | 3 | 34 | 31 | .523 | 7-3 | W4 | 65 |
| 6/15/2021 | | | Tex | W | Sano | 3 | 0 | 35 | 31 | .530 | 7-3 | W5 | 66 |
| 6/16/2021 | | | Tex | L | | 4 | 5 | 35 | 32 | .522 | 6-4 | L1 | 67 |
| 6/17/2021 | | | ChA | L | | 3 | 17 | 35 | 33 | .515 | 6-4 | L2 | 68 |
| 6/18/2021 | | | ChA | W | Soto,J | 7 | 6 | 36 | 33 | .522 | 6-4 | W1 | 69 |
| 6/19/2021 | | | ChA | W | Sano | 8 | 5 | 37 | 33 | .529 | 7-3 | W2 | 70 |
| 6/20/2021 | | | ChA | W | Raleigh | 6 | 3 | 38 | 33 | .535 | 8-2 | W3 | 71 |
| 6/21/2021 | | @ | Bal | W | Blackmon | 6 | 5 | 39 | 33 | .542 | 8-2 | W4 | 72 |
| 6/22/2021 | | @ | Bal | W | Castro,S | 12 | 8 | 40 | 33 | .548 | 8-2 | W5 | 73 |
| 6/23/2021 | | @ | Bal | L | | 7 | 10 | 40 | 34 | .541 | 7-3 | L1 | 74 |
| 6/24/2021 | | @ | Det | L | | 2 | 5 | 40 | 35 | .533 | 6-4 | L2 | 75 |
| 6/25/2021 | | @ | Det | W | Sano | 11 | 8 | 41 | 35 | .539 | 6-4 | W1 | 76 |
| 6/26/2021 | | @ | Det | L | | 1 | 4 | 41 | 36 | .532 | 6-4 | L1 | 77 |
| 6/27/2021 | | @ | Det | W | Soto,J | 3 | 2 | 42 | 36 | .538 | 7-3 | W1 | 78 |
| 6/28/2021 | | | Bal | L | | 4 | 5 | 42 | 37 | .532 | 6-4 | L1 | 79 |
| 6/29/2021 | | | Bal | W | Soler | 6 | 5 | 43 | 37 | .538 | 6-4 | W1 | 80 |
| 6/30/2021 | | | Bal | W | | 5 | 4 | 44 | 37 | .543 | 6-4 | W2 | 81 |
| 7/1/2021 | | @ | Cle | W | Sanchez,G | 4 | 0 | 45 | 37 | .549 | 6-4 | W3 | 82 |
| 7/2/2021 | | @ | Cle | L | | 4 | 6 | 45 | 38 | .542 | 5-5 | L1 | 83 |
| 7/3/2021 | | @ | Cle | W | Raleigh | 7 | 2 | 46 | 38 | .548 | 6-4 | W1 | 84 |
| 7/4/2021 | | @ | Cle | L | | 5 | 6 | 46 | 39 | .541 | 6-4 | L1 | 85 |
| 7/6/2021 | | | Oak | W | Soler | 12 | 3 | 47 | 39 | .547 | 6-4 | W1 | 86 |
| 7/7/2021 | | | Oak | W | Sano | 7 | 6 | 48 | 39 | .552 | 7-3 | W2 | 87 |
| 7/8/2021 | | | Oak | L | | 1 | 8 | 48 | 40 | .545 | 6-4 | L1 | 88 |
| 7/9/2021 | | | NYA | L | | 8 | 9 | 48 | 41 | .539 | 6-4 | L2 | 89 |
| 7/10/2021 | | | NYA | L | | 3 | 6 | 48 | 42 | .533 | 5-5 | L3 | 90 |
| 7/11/2021 | | | NYA | W | Soler | 6 | 4 | 49 | 42 | .538 | 5-5 | W1 | 91 |
| 7/16/2021 | | @ | ChA | L | | 5 | 7 | 49 | 43 | .533 | 4-6 | L1 | 92 |
| 7/17/2021 | | @ | ChA | W | Soler | 6 | 5 | 50 | 43 | .538 | 5-5 | W1 | 93 |
| 7/18/2021 | | @ | ChA | W | Castro,S | 6 | 1 | 51 | 43 | .543 | 5-5 | W2 | 94 |
| 7/19/2021 | | | Cle | W | Raleigh | 4 | 3 | 52 | 43 | .547 | 6-4 | W3 | 95 |
| 7/20/2021 | | | Cle | W | Hilliard | 6 | 3 | 53 | 43 | .552 | 6-4 | W4 | 96 |
| 7/21/2021 | | | Cle | L | | 6 | 9 | 53 | 44 | .546 | 5-5 | L1 | 97 |
| 7/23/2021 | | | Tex | W | Raleigh | 6 | 4 | 54 | 44 | .551 | 6-4 | W1 | 98 |
| 7/24/2021 | | | Tex | W | Sano | 9 | 4 | 55 | 44 | .556 | 7-3 | W2 | 99 |
| 7/25/2021 | | | Tex | W | | 18 | 6 | 56 | 44 | .560 | 8-2 | W3 | 100 |
| 7/26/2021 | | @ | Sea | W | Sano | 7 | 1 | 57 | 44 | .564 | 8-2 | W4 | 101 |
| 7/27/2021 | | @ | Sea | W | Anderson,Ti | 2 | 0 | 58 | 44 | .569 | 9-1 | W5 | 102 |
| 7/28/2021 | | @ | Sea | L | | 1 | 4 | 58 | 45 | .563 | 8-2 | L1 | 103 |
| 7/30/2021 | | @ | SF | L | | 5 | 6 | 58 | 46 | .558 | 7-3 | L2 | 104 |
| 7/31/2021 | | @ | SF | W | Sano | 7 | 3 | 59 | 46 | .562 | 7-3 | W1 | 105 |
| 8/1/2021 | | @ | SF | W | Soler | 8 | 3 | 60 | 46 | .566 | 7-3 | W2 | 106 |
| 8/3/2021 | | @ | LAN | L | | 0 | 4 | 60 | 47 | .561 | 7-3 | L1 | 107 |
| 8/4/2021 | | @ | LAN | L | | 2 | 3 | 60 | 48 | .556 | 6-4 | L2 | 108 |
| 8/5/2021 | | | Min | W | Polanco,J | 19 | 8 | 61 | 48 | .560 | 6-4 | W1 | 109 |
| 8/6/2021 | | | Min | W | Tellez | 8 | 0 | 62 | 48 | .564 | 6-4 | W2 | 110 |
| 8/7/2021 | | | Min | L | | 5 | 18 | 62 | 49 | .559 | 5-5 | L1 | 111 |
| 8/8/2021 | | | Min | W | Sano | 6 | 1 | 63 | 49 | .563 | 5-5 | W1 | 112 |
| 8/10/2021 | | | Col | W | Sano | 10 | 4 | 64 | 49 | .566 | 6-4 | W2 | 113 |
| 8/11/2021 | | | Col | W | Soto,J | 5 | 1 | 65 | 49 | .570 | 7-3 | W3 | 114 |
| 8/13/2021 | | @ | LAA | W | Sanchez,G | 6 | 2 | 66 | 49 | .574 | 7-3 | W4 | 115 |
| 8/14/2021 | | @ | LAA | W | | 7 | 5 | 67 | 49 | .578 | 7-3 | W5 | 116 |
| 8/15/2021 | | @ | LAA | W | Sano | 12 | 1 | 68 | 49 | .581 | 8-2 | W6 | 117 |
| 8/16/2021 | | @ | KC | W | Soler | 11 | 9 | 69 | 49 | .585 | 9-1 | W7 | 118 |
| 8/17/2021 | | @ | KC | W | McKinney,B | 6 | 3 | 70 | 49 | .588 | 9-1 | W8 | 119 |
| 8/18/2021 | | @ | KC | L | | 1 | 2 | 70 | 50 | .583 | 8-2 | L1 | 120 |
| 8/19/2021 | | @ | KC | L | | 4 | 5 | 70 | 51 | .579 | 8-2 | L2 | 121 |
| 8/20/2021 | | | Sea | W | Soler | 17 | 4 | 71 | 51 | .582 | 8-2 | W1 | 122 |
| 8/21/2021 | | | Sea | W | Soler | 8 | 4 | 72 | 51 | .585 | 8-2 | W2 | 123 |
| 8/22/2021 | | | Sea | W | Soler | 8 | 0 | 73 | 51 | .589 | 8-2 | W3 | 124 |
| 8/23/2021 | | | KC | L | | 7 | 13 | 73 | 52 | .584 | 7-3 | L1 | 125 |
| 8/24/2021 | | | KC | W | Tellez | 9 | 3 | 74 | 52 | .587 | 7-3 | W1 | 126 |
| 8/25/2021 | | | KC | W | Soler | 8 | 6 | 75 | 52 | .591 | 7-3 | W2 | 127 |
| 8/27/2021 | | @ | Tex | W | Anderson,Ti | 11 | 8 | 76 | 52 | .594 | 7-3 | W3 | 128 |
| 8/28/2021 | | @ | Tex | W | Soto,J | 9 | 8 | 77 | 52 | .597 | 7-3 | W4 | 129 |
| 8/29/2021 | | @ | Tex | W | Soto,J | 6 | 3 | 78 | 52 | .600 | 8-2 | W5 | 130 |
| 8/30/2021 | | @ | Sea | W | Soto,J | 4 | 3 | 79 | 52 | .603 | 9-1 | W6 | 131 |
| 8/31/2021 | | @ | Sea | L | | 4 | 7 | 79 | 53 | .598 | 8-2 | L1 | 132 |
| 9/1/2021 | | @ | Sea | W | Blackmon | 19 | 2 | 80 | 53 | .602 | 8-2 | W1 | 133 |
| 9/3/2021 | | @ | SD | W | Sano | 7 | 5 | 81 | 53 | .604 | 8-2 | W2 | 134 |
| 9/4/2021 | | @ | SD | W | Anderson,Ti | 4 | 3 | 82 | 53 | .607 | 9-1 | W3 | 135 |
| 9/5/2021 | | @ | SD | L | | 4 | 11 | 82 | 54 | .603 | 8-2 | L1 | 136 |
| 9/6/2021 | | | Sea | W | Sano | 16 | 0 | 83 | 54 | .606 | 8-2 | W1 | 137 |
| 9/7/2021 | | | Sea | W | Soto,J | 6 | 0 | 84 | 54 | .609 | 8-2 | W2 | 138 |
| 9/8/2021 | | | Sea | W | Soto,J | 6 | 3 | 85 | 54 | .612 | 8-2 | W3 | 139 |
| 9/10/2021 | | | LAA | L | | 3 | 4 | 85 | 55 | .607 | 7-3 | L1 | 140 |
| 9/11/2021 | | | LAA | L | | 1 | 7 | 85 | 56 | .603 | 6-4 | L2 | 141 |
| 9/12/2021 | | | LAA | L | | 2 | 5 | 85 | 57 | .599 | 6-4 | L3 | 142 |
| 9/13/2021 | | @ | Tex | W | Sanchez,G | 5 | 4 | 86 | 57 | .601 | 6-4 | W1 | 143 |
| 9/14/2021 | | @ | Tex | W | Sano | 9 | 4 | 87 | 57 | .604 | 6-4 | W2 | 144 |
| 9/15/2021 | | @ | Tex | W | Soto,J | 19 | 8 | 88 | 57 | .607 | 6-4 | W3 | 145 |
| 9/16/2021 | | @ | Tex | W | Soto,J | 10 | 2 | 89 | 57 | .610 | 7-3 | W4 | 146 |
| 9/17/2021 | | | Ari | L | | 5 | 6 | 89 | 58 | .605 | 6-4 | L1 | 147 |
| 9/18/2021 | | | Ari | L | | 0 | 6 | 89 | 59 | .601 | 5-5 | L2 | 148 |
| 9/19/2021 | | | Ari | L | | 6 | 7 | 89 | 60 | .597 | 4-6 | L3 | 149 |
| 9/20/2021 | | @ | LAA | W | Sanchez,G | 3 | 2 | 90 | 60 | .600 | 5-5 | W1 | 150 |
| 9/21/2021 | | @ | LAA | L | | 1 | 9 | 90 | 61 | .596 | 5-5 | L1 | 151 |
| 9/22/2021 | | @ | LAA | L | | 2 | 8 | 90 | 62 | .592 | 5-5 | L2 | 152 |
| 9/23/2021 | | @ | LAA | L | | 2 | 3 | 90 | 63 | .588 | 4-6 | L3 | 153 |
| 9/24/2021 | | @ | Oak | L | | 1 | 10 | 90 | 64 | .584 | 3-7 | L4 | 154 |
| 9/25/2021 | | @ | Oak | W | Polanco,J | 4 | 0 | 91 | 64 | .587 | 3-7 | W1 | 155 |
| 9/26/2021 | | @ | Oak | W | Blackmon | 4 | 3 | 92 | 64 | .590 | 3-7 | W2 | 156 |
| 9/28/2021 | | | Tam | L | | 4 | 10 | 92 | 65 | .586 | 3-7 | L1 | 157 |
| 9/29/2021 | | | Tam | W | Sanchez,G | 4 | 3 | 93 | 65 | .589 | 4-6 | W1 | 158 |
| 9/30/2021 | | | Tam | W | Sano | 2 | 1 | 94 | 65 | .591 | 5-5 | W2 | 159 |
| 10/1/2021 | | | Oak | L | | 3 | 6 | 94 | 66 | .587 | 4-6 | L1 | 160 |
| 10/2/2021 | | | Oak | W | Casey | 7 | 5 | 95 | 66 | .590 | 5-5 | W1 | 161 |
| 10/3/2021 | | | Oak | L | | 9 | 10 | 95 | 67 | .586 | 5-5 | L1 | 162 |
