| Batting average | | On-base percentage | | Slugging percentage |
| | | | | | | | | | | |
| Hafner | Bos | .343 | | Hafner | Bos | .459 | | Hafner | Bos | .690 |
| Pujols | NYA | .339 | | Bonds | Tor | .450 | | Pujols | NYA | .615 |
| German,E | Min | .338 | | Drew,JD | Bos | .424 | | Bonds | Tor | .580 |
| Helton | KC | .335 | | Helton | KC | .423 | | Howard,R | Min | .575 |
| Martinez,V | Bos | .335 | | German,E | Min | .412 | | Lee,D | Tor | .573 |
| Jeter | NYA | .329 | | Jeter | NYA | .409 | | Ortiz,D | Bal | .572 |
| Matsui,H | Bal | .328 | | Cust | Tor | .408 | | Delgado,C | Sea | .559 |
| Crawford | Bal | .328 | | Matsui,H | Bal | .402 | | Jones,C | KC | .554 |
| Butler | Tam | .319 | | Martinez,V | Bos | .400 | | Thomas,F | Oak | .539 |
| Mauer | NYA | .319 | | Thomas,F | Oak | .399 | | Guillen,J | Min | .532 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Hits | | Runs | | Runs batted in |
| | | | | | | | | | | |
| Pujols | NYA | 228 | | Jeter | NYA | 153 | | Hafner | Bos | 170 |
| Jeter | NYA | 225 | | Drew,JD | Bos | 150 | | Lee,D | Tor | 169 |
| German,E | Min | 221 | | Hafner | Bos | 146 | | Pujols | NYA | 168 |
| Young,Dlm | Det | 218 | | Cameron | Oak | 131 | | Lee,Ca | Bos | 152 |
| Martinez,V | Bos | 217 | | Rodriguez,A | NYA | 130 | | Delgado,C | Sea | 136 |
| Lopez,Jo | Sea | 214 | | Cust | Tor | 128 | | Ortiz,D | Bal | 135 |
| Helton | KC | 206 | | Lee,Ca | Bos | 128 | | Guillen,J | Min | 133 |
| Young,M | Bos | 206 | | Helton | KC | 127 | | LaRoche,An | Tex | 125 |
| Hafner | Bos | 204 | | Pujols | NYA | 127 | | Young,Dlm | Det | 124 |
| Crawford | Bal | 204 | | Sizemore | NYA | 123 | | Ruggiano | Tor | 123 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Doubles | | Triples | | Homeruns |
| | | | | | | | | | | |
| Ruggiano | Tor | 63 | | Ethier | Sea | 16 | | Ortiz,D | Bal | 57 |
| Hafner | Bos | 57 | | Furcal | Tor | 13 | | Hafner | Bos | 49 |
| Helton | KC | 54 | | Drew,S | Det | 12 | | Howard,R | Min | 47 |
| LaRoche,An | Tex | 54 | | Crawford | Bal | 12 | | Pujols | NYA | 47 |
| Lee,D | Tor | 51 | | Sullivan | LAA | 12 | | Thomas,F | Oak | 45 |
| Young,M | Bos | 48 | | Young,Dlm | Det | 11 | | Delgado,C | Sea | 42 |
| Votto | LAA | 47 | | Hudson,O | | 9 | | Swisher | Sea | 41 |
| Cameron | Oak | 47 | | Lofton | Tam | 9 | | Lee,D | Tor | 41 |
| DeJesus | LAA | 46 | | Kemp | Min | 9 | | Guillen,J | Min | 38 |
| Pujols | NYA | 45 | | Izturis,M | Tam | 8 | | Lee,Ca | Bos | 38 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Extra base hits | | Stolen bases | | Steal percentage |
| | | | | | | | | | | |
| Hafner | Bos | 107 | | German,E | Min | 64-16 | | Furcal | Tor | .964 |
| Lee,D | Tor | 95 | | Crawford | Bal | 58-20 | | Fields | Min | .960 |
| Pujols | NYA | 92 | | Willits | Tam | 49-25 | | Jones,Ja | Tex | .955 |
| Ruggiano | Tor | 88 | | Jeter | NYA | 48-9 | | Lofton | Tam | .902 |
| Delgado,C | Sea | 85 | | Lofton | Tam | 46-5 | | Lugo,J | Oak | .900 |
| LaRoche,An | Tex | 85 | | Casilla,A | Min | 44-17 | | Bloomquist | Sea | .882 |
| Ortiz,D | Bal | 81 | | Hart | ChA | 41-20 | | Jeter | NYA | .842 |
| Hall,B | Oak | 74 | | Cameron | Oak | 38-9 | | Lee,Ca | Bos | .833 |
| Sizemore | NYA | 74 | | Izturis,M | Tam | 32-14 | | Beltran | | .810 |
| Votto | LAA | 73 | | Reyes,J | Tex | 31-11 | | Cameron | Oak | .809 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Walks | | Intentional walks | | Strikeouts |
| | | | | | | | | | | |
| Cust | Tor | 146 | | Howard,R | Min | 26 | | Cameron | Oak | 193 |
| Drew,JD | Bos | 134 | | Ortiz,D | Bal | 21 | | Howard,R | Min | 188 |
| Hafner | Bos | 125 | | Hafner | Bos | 21 | | Hall,B | Oak | 188 |
| Bonds | Tor | 118 | | Bonds | Tor | 19 | | Pena,W | | 181 |
| Thomas,F | Oak | 111 | | Kouzmanoff | | 11 | | Peralta,Jh | Min | 176 |
| Ensberg | Sea | 110 | | Gordon,A | Det | 9 | | Swisher | Sea | 171 |
| Swisher | Sea | 109 | | Jones,C | KC | 7 | | Ruggiano | Tor | 171 |
| Ortiz,D | Bal | 105 | | Rodriguez,A | NYA | 7 | | Church | Sea | 166 |
| Cameron | Oak | 95 | | Crisp | Bos | 6 | | Cust | Tor | 164 |
| Helton | KC | 94 | | Votto | LAA | 6 | | Hart | ChA | 163 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Sacrifice bunts | | Sacrifice flies | | Hit by pitch |
| | | | | | | | | | | |
| Polanco | Tor | 13 | | Votto | LAA | 11 | | Doumit | Oak | 18 |
| Jeter | NYA | 12 | | Lee,Ca | Bos | 11 | | Gordon,A | Det | 17 |
| Ellis | Oak | 10 | | Pena,W | | 10 | | Polanco | Tor | 17 |
| Catalanotto | Tam | 9 | | Fielder | Det | 10 | | Nady | Tex | 15 |
| Church | Sea | 9 | | Pedroia | Bos | 10 | | Guillen,J | Min | 14 |
| German,E | Min | 9 | | Ramirez,A | Bal | 10 | | German,E | Min | 13 |
| Iguchi | ChA | 8 | | Rodriguez,A | NYA | 10 | | Jenkins | ChA | 12 |
| Pedroia | Bos | 8 | | Ortiz,D | Bal | 10 | | Uggla | | 11 |
| Crisp | Bos | 8 | | Lee,D | Tor | 10 | | Gonzalez,E | Tam | 11 |
| Molina,J | Sea | 7 | | Young,M | Bos | 10 | | Lopez,Jo | Sea | 11 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Ground ball DP | | Runs created | | Runs created/27 outs |
| | | | | | | | | | | |
| Hunter | KC | 34 | | Hafner | Bos | 192.3 | | Hafner | Bos | 12.7 |
| Gonzalez,Ad | ChA | 26 | | Pujols | NYA | 156.6 | | Bonds | Tor | 9.4 |
| Lee,D | Tor | 26 | | Drew,JD | Bos | 145.7 | | Pujols | NYA | 8.8 |
| Pujols | NYA | 26 | | Jeter | NYA | 141.6 | | Helton | KC | 8.7 |
| Butler | Tam | 25 | | Helton | KC | 137.6 | | Drew,JD | Bos | 8.7 |
| Young,Dlm | Det | 25 | | German,E | Min | 136.2 | | Matsui,H | Bal | 8.3 |
| Polanco | Tor | 24 | | Lee,D | Tor | 129.6 | | Thomas,F | Oak | 8.0 |
| Jones,C | KC | 23 | | Thomas,F | Oak | 129.0 | | Howard,R | Min | 7.8 |
| Swisher | Sea | 23 | | Martinez,V | Bos | 128.6 | | German,E | Min | 7.7 |
| Lee,Ca | Bos | 23 | | Ortiz,D | Bal | 127.5 | | Martinez,V | Bos | 7.7 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Isolated power | | Total average | | Total bases |
| | | | | | | | | | | |
| Hafner | Bos | .347 | | Hafner | Bos | 1.332 | | Pujols | NYA | 414 |
| Ortiz,D | Bal | .322 | | Bonds | Tor | 1.161 | | Hafner | Bos | 410 |
| Howard,R | Min | .299 | | Pujols | NYA | 1.032 | | Lee,D | Tor | 383 |
| Bonds | Tor | .292 | | Drew,JD | Bos | 1.029 | | Lee,Ca | Bos | 348 |
| Delgado,C | Sea | .291 | | Howard,R | Min | 1.002 | | Ortiz,D | Bal | 346 |
| Pujols | NYA | .276 | | Thomas,F | Oak | 1.000 | | LaRoche,An | Tex | 338 |
| Lee,D | Tor | .269 | | German,E | Min | .987 | | Guerrero | NYA | 336 |
| Swisher | Sea | .266 | | Ortiz,D | Bal | .979 | | Young,Dlm | Det | 334 |
| Jones,C | KC | .265 | | Helton | KC | .971 | | Delgado,C | Sea | 325 |
| Thomas,F | Oak | .258 | | Jeter | NYA | .967 | | Guillen,J | Min | 324 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| On-base plus slugging | | Secondary average | | AB per homerun |
| | | | | | | | | | | |
| Hafner | Bos | 1.150 | | Bonds | Tor | .582 | | Ortiz,D | Bal | 10.6 |
| Bonds | Tor | 1.030 | | Hafner | Bos | .556 | | Howard,R | Min | 11.5 |
| Pujols | NYA | 1.012 | | Ortiz,D | Bal | .499 | | Hafner | Bos | 12.1 |
| Howard,R | Min | .959 | | Howard,R | Min | .466 | | Thomas,F | Oak | 12.7 |
| Thomas,F | Oak | .939 | | Thomas,F | Oak | .455 | | Bonds | Tor | 12.9 |
| Lee,D | Tor | .932 | | Swisher | Sea | .454 | | Delgado,C | Sea | 13.8 |
| Delgado,C | Sea | .931 | | Delgado,C | Sea | .446 | | Swisher | Sea | 14.1 |
| Jones,C | KC | .931 | | Cust | Tor | .442 | | Pujols | NYA | 14.3 |
| Ortiz,D | Bal | .929 | | Drew,JD | Bos | .427 | | Jones,C | KC | 14.5 |
| Drew,JD | Bos | .927 | | Jones,C | KC | .420 | | Guillen,J | Min | 16.0 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Atbats | | Plate appearances | | Games |
| | | | | | | | | | | |
| Ethier | Sea | 707 | | Jeter | NYA | 797 | | Biggio | LAA | 162 |
| Young,Dlm | Det | 691 | | Ethier | Sea | 779 | | Cabrera,Me | KC | 162 |
| Lopez,Jo | Sea | 685 | | Cameron | Oak | 776 | | Cameron | Oak | 162 |
| Jeter | NYA | 684 | | Drew,JD | Bos | 767 | | Church | Sea | 162 |
| Young,M | Bos | 684 | | German,E | Min | 761 | | Crisp | Bos | 162 |
| Hart | ChA | 679 | | Lee,Ca | Bos | 752 | | Drew,JD | Bos | 162 |
| Lee,Ca | Bos | 676 | | Young,M | Bos | 750 | | Ensberg | Sea | 162 |
| Pujols | NYA | 673 | | Pujols | NYA | 748 | | Ethier | Sea | 162 |
| Cameron | Oak | 671 | | Polanco | Tor | 745 | | German,E | Min | 162 |
| DeJesus | LAA | 670 | | DeJesus | LAA | 741 | | Gonzalez,Ad | ChA | 162 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Current hit streak | | Longest hit streak | | |
| | | | | | | | | | | |
| Lopez,Jo | Sea | 18 | | German,E | Min | 30 | | | | |
| Church | Sea | 11 | | Jeter | NYA | 22 | | | | |
| Guerrero | NYA | 11 | | Lopez,Jo | Sea | 18 | | | | |
| Beltran | | 8 | | Crisp | Bos | 17 | | | | |
| LaRoche,An | Tex | 8 | | Martinez,V | Bos | 17 | | | | |
| Polanco | Tor | 8 | | Mauer | NYA | 17 | | | | |
| Gonzalez,Ad | ChA | 7 | | Butler | Tam | 16 | | | | |
| Kottaras | Min | 7 | | Drew,JD | Bos | 16 | | | | |
| Pujols | NYA | 7 | | Drew,S | Det | 16 | | | | |
| Bard | Tex | 6 | | Izturis,M | Tam | 16 | | | | |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Total bases + BB + HBP | | TB+BB+HBP rate | | Plate appearances per game |
| | | | | | | | | | | |
| Hafner | Bos | 540 | | Hafner | Bos | .743 | | Jeter | NYA | 4.98 |
| Pujols | NYA | 483 | | Bonds | Tor | .672 | | Helton | KC | 4.84 |
| Ortiz,D | Bal | 453 | | Pujols | NYA | .646 | | Ethier | Sea | 4.81 |
| Drew,JD | Bos | 452 | | Howard,R | Min | .635 | | Cameron | Oak | 4.79 |
| Lee,D | Tor | 446 | | Ortiz,D | Bal | .627 | | DeJesus | LAA | 4.78 |
| Thomas,F | Oak | 426 | | Delgado,C | Sea | .619 | | Drew,JD | Bos | 4.73 |
| Delgado,C | Sea | 423 | | Thomas,F | Oak | .612 | | German,E | Min | 4.70 |
| Swisher | Sea | 420 | | Jones,C | KC | .605 | | Izturis,M | Tam | 4.68 |
| Jeter | NYA | 420 | | Lee,D | Tor | .602 | | Pujols | NYA | 4.68 |
| Lee,Ca | Bos | 413 | | Swisher | Sea | .602 | | Uggla | | 4.67 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Total bases plus walks | | TB+BB rate | | AB per game |
| | | | | | | | | | | |
| Hafner | Bos | 535 | | Hafner | Bos | .736 | | Ethier | Sea | 4.36 |
| Pujols | NYA | 475 | | Bonds | Tor | .667 | | DeJesus | LAA | 4.32 |
| Ortiz,D | Bal | 451 | | Pujols | NYA | .635 | | Young,Dlm | Det | 4.29 |
| Drew,JD | Bos | 449 | | Howard,R | Min | .626 | | Jeter | NYA | 4.28 |
| Lee,D | Tor | 442 | | Ortiz,D | Bal | .624 | | Lopez,Jo | Sea | 4.23 |
| Thomas,F | Oak | 420 | | Delgado,C | Sea | .608 | | Uggla | | 4.23 |
| Delgado,C | Sea | 415 | | Jones,C | KC | .605 | | Young,M | Bos | 4.22 |
| Jeter | NYA | 415 | | Thomas,F | Oak | .603 | | Pujols | NYA | 4.21 |
| Swisher | Sea | 413 | | Lee,D | Tor | .596 | | Hart | ChA | 4.19 |
| Lee,Ca | Bos | 412 | | Swisher | Sea | .592 | | Ramirez,A | Bal | 4.18 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Balls in park | | In-play average | | Strikeout/walk ratio |
| | | | | | | | | | | |
| Polanco | Tor | 632 | | Hafner | Bos | .396 | | Bonds | Tor | 0.5 |
| Lopez,Jo | Sea | 592 | | Peralta,Jh | Min | .382 | | Pujols | NYA | 0.9 |
| Young,M | Bos | 590 | | German,E | Min | .378 | | Helton | KC | 0.9 |
| DeJesus | LAA | 582 | | Gonzalez,E | Tam | .374 | | Thomas,F | Oak | 0.9 |
| Cabrera,Me | KC | 579 | | Ruggiano | Tor | .371 | | Drew,JD | Bos | 0.9 |
| Pujols | NYA | 579 | | Young,Dlm | Det | .368 | | Willits | Tam | 1.0 |
| Lee,Ca | Bos | 575 | | Helton | KC | .366 | | Matsui,H | Bal | 1.0 |
| Jeter | NYA | 562 | | Jeter | NYA | .365 | | Callaspo | NYA | 1.0 |
| German,E | Min | 558 | | Martinez,V | Bos | .356 | | Catalanotto | Tam | 1.0 |
| Guerrero | NYA | 557 | | Butler | Tam | .355 | | Pedroia | Bos | 1.1 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Batting average vs LHP | | On-base percentage vs LHP | | Slugging percentage vs LHP |
| | | | | | | | | | | |
| Butler | Tam | .388 | | Thomas,F | Oak | .459 | | Butler | Tam | .669 |
| Hillenbrand | | .387 | | German,E | Min | .444 | | Thomas,F | Oak | .667 |
| Gonzalez,Ad | ChA | .379 | | Hafner | Bos | .436 | | Wood,B | ChA | .653 |
| German,E | Min | .372 | | Jeter | NYA | .436 | | Guerrero | NYA | .627 |
| Jeter | NYA | .369 | | Butler | Tam | .435 | | Furcal | Tor | .606 |
| Sheffield | NYA | .364 | | Swisher | Sea | .430 | | Hillenbrand | | .600 |
| Izturis,M | Tam | .358 | | Hillenbrand | | .423 | | Kouzmanoff | | .594 |
| Kouzmanoff | | .358 | | Hyzdu | Tor | .422 | | Hyzdu | Tor | .583 |
| Martinez,V | Bos | .352 | | Fields | Min | .420 | | Hafner | Bos | .582 |
| Michaels | Tor | .341 | | Martinez,V | Bos | .419 | | Swisher | Sea | .576 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Hits vs LHP | | Runs batted in vs LHP | | On-base plus slugging vs LHP |
| | | | | | | | | | | |
| Gonzalez,Ad | ChA | 91 | | LaRoche,An | Tex | 51 | | Thomas,F | Oak | 1.126 |
| Jeter | NYA | 86 | | Guerrero | NYA | 50 | | Butler | Tam | 1.104 |
| German,E | Min | 80 | | Pujols | NYA | 50 | | Hillenbrand | | 1.023 |
| Pujols | NYA | 79 | | Delgado,C | Sea | 49 | | Hafner | Bos | 1.019 |
| Young,Dlm | Det | 76 | | Lee,D | Tor | 47 | | Wood,B | ChA | 1.016 |
| Lopez,Jo | Sea | 75 | | Lee,Ca | Bos | 45 | | Kouzmanoff | | 1.010 |
| Nady | Tex | 73 | | Ortiz,D | Bal | 44 | | Guerrero | NYA | 1.007 |
| Sheffield | NYA | 72 | | Thomas,F | Oak | 43 | | Swisher | Sea | 1.006 |
| Guerrero | NYA | 72 | | Hafner | Bos | 43 | | Hyzdu | Tor | 1.005 |
| Helton | KC | 71 | | Howard,R | Min | 43 | | Baker,Je | | .986 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Doubles vs LHP | | Triples vs LHP | | Homeruns vs LHP |
| | | | | | | | | | | |
| Ruggiano | Tor | 31 | | Ethier | Sea | 6 | | Thomas,F | Oak | 19 |
| Guerrero | NYA | 24 | | Young,Dlm | Det | 6 | | Ortiz,D | Bal | 18 |
| Delgado,C | Sea | 22 | | Furcal | Tor | 5 | | Howard,R | Min | 17 |
| Hall,B | Oak | 20 | | Johnson,K | KC | 5 | | Fielder | Det | 14 |
| Izturis,M | Tam | 19 | | Sullivan | LAA | 4 | | Guerrero | NYA | 14 |
| Mathis | Min | 18 | | Lofton | Tam | 3 | | Hairston,S | Bal | 13 |
| Michaels | Tor | 18 | | Watson,M | | 3 | | Butler | Tam | 12 |
| Casilla,A | Min | 18 | | Reyes,J | Tex | 3 | | Swisher | Sea | 12 |
| LaRoche,An | Tex | 18 | | Werth | | 3 | | Pujols | NYA | 12 |
| Young,Dlm | Det | 18 | | Helms | Bal | 3 | | Glaus | Oak | 11 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Extra base hits vs LHP | | Total bases vs LHP | | Isolated power vs LHP |
| | | | | | | | | | | |
| Guerrero | NYA | 38 | | Guerrero | NYA | 138 | | Thomas,F | Oak | .377 |
| Ruggiano | Tor | 34 | | Gonzalez,Ad | ChA | 133 | | Wood,B | ChA | .347 |
| Delgado,C | Sea | 32 | | Pujols | NYA | 131 | | Hyzdu | Tor | .301 |
| Wood,B | ChA | 29 | | Lopez,Jo | Sea | 125 | | Guerrero | NYA | .300 |
| Hall,B | Oak | 29 | | Jeter | NYA | 123 | | Howard,R | Min | .293 |
| LaRoche,An | Tex | 29 | | Young,Dlm | Det | 121 | | Ortiz,D | Bal | .287 |
| Young,Dlm | Det | 29 | | Butler | Tam | 119 | | Butler | Tam | .281 |
| Lopez,Jo | Sea | 28 | | LaRoche,An | Tex | 116 | | Furcal | Tor | .267 |
| Pujols | NYA | 28 | | Hafner | Bos | 113 | | Delgado,C | Sea | .265 |
| Hafner | Bos | 27 | | Peralta,Jh | Min | 113 | | Hall,B | Oak | .253 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Walks vs LHP | | Strikeouts vs LHP | | Hit by pitch vs LHP |
| | | | | | | | | | | |
| Ensberg | Sea | 53 | | Howard,R | Min | 86 | | Jenkins | ChA | 8 |
| Thomas,F | Oak | 49 | | Church | Sea | 73 | | Doumit | Oak | 8 |
| Cust | Tor | 40 | | Peralta,Jh | Min | 67 | | Ethier | Sea | 8 |
| Hyzdu | Tor | 40 | | Pena,W | | 65 | | Delgado,C | Sea | 7 |
| Rodriguez,A | NYA | 40 | | Hall,B | Oak | 64 | | Hermida | Det | 6 |
| Cameron | Oak | 37 | | Gordon,A | Det | 64 | | Howard,R | Min | 6 |
| Peralta,Jh | Min | 35 | | Hafner | Bos | 61 | | Kennedy,A | Tex | 5 |
| Drew,JD | Bos | 34 | | Fielder | Det | 57 | | Hafner | Bos | 5 |
| Swisher | Sea | 33 | | Sullivan | LAA | 57 | | Gordon,A | Det | 5 |
| Cuddyer | Min | 32 | | Hart | ChA | 56 | | Cust | Tor | 4 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Sacrifice bunts vs LHP | | Sacrifice flies vs LHP | | Atbats vs LHP |
| | | | | | | | | | | |
| Catalanotto | Tam | 8 | | Biggio | LAA | 5 | | Matthews | Cle | 246 |
| Crisp | Bos | 5 | | Furcal | Tor | 4 | | Young,Dlm | Det | 242 |
| German,E | Min | 5 | | Pedroia | Bos | 4 | | Ethier | Sea | 240 |
| Thigpen | Tor | 4 | | Jones,C | KC | 4 | | Gonzalez,Ad | ChA | 240 |
| Ellis | Oak | 4 | | Lee,D | Tor | 4 | | Hart | ChA | 238 |
| Pedroia | Bos | 4 | | Ortiz,D | Bal | 4 | | Pujols | NYA | 235 |
| Church | Sea | 4 | | Hunter | KC | 4 | | Jeter | NYA | 233 |
| Jeter | NYA | 4 | | Rodriguez,A | NYA | 4 | | Lopez,Jo | Sea | 229 |
| Tyner | Tex | 3 | | Votto | LAA | 4 | | Cabrera,Me | KC | 226 |
| Hulett | LAA | 3 | | Walker,To | | 3 | | Gordon,A | Det | 226 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| AB per homerun vs LHP | | AB per double vs LHP | | Plate appearances vs LHP |
| | | | | | | | | | | |
| Thomas,F | Oak | 8.4 | | Ruggiano | Tor | 5.6 | | Matthews | Cle | 269 |
| Ortiz,D | Bal | 10.8 | | Izturis,M | Tam | 7.1 | | Jeter | NYA | 268 |
| Howard,R | Min | 12.1 | | Mathis | Min | 8.3 | | Ethier | Sea | 263 |
| Wood,B | ChA | 14.7 | | Wood,B | ChA | 8.6 | | Hart | ChA | 263 |
| Hyzdu | Tor | 14.8 | | Hillenbrand | | 8.8 | | Peralta,Jh | Min | 256 |
| Butler | Tam | 14.8 | | Delgado,C | Sea | 8.9 | | Gonzalez,Ad | ChA | 255 |
| Fielder | Det | 14.9 | | Guerrero | NYA | 9.2 | | Cabrera,Me | KC | 254 |
| Cuddyer | Min | 15.5 | | Hall,B | Oak | 9.3 | | German,E | Min | 253 |
| Guerrero | NYA | 15.7 | | Michaels | Tor | 9.8 | | Young,Dlm | Det | 251 |
| Swisher | Sea | 15.9 | | Matsui,H | Bal | 11.1 | | Pujols | NYA | 248 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Batting average vs RHP | | On-base percentage vs RHP | | Slugging percentage vs RHP |
| | | | | | | | | | | |
| Mauer | NYA | .356 | | Hafner | Bos | .470 | | Hafner | Bos | .743 |
| Hafner | Bos | .345 | | Bonds | Tor | .454 | | Pujols | NYA | .646 |
| Pujols | NYA | .340 | | Drew,JD | Bos | .447 | | Eldred | Min | .637 |
| Helton | KC | .333 | | Helton | KC | .428 | | Ortiz,D | Bal | .615 |
| Jacobs | Oak | .331 | | Gordon,A | Det | .426 | | Jacobs | Oak | .613 |
| Sizemore | NYA | .330 | | Mauer | NYA | .422 | | Sizemore | NYA | .607 |
| Martinez,V | Bos | .327 | | Pujols | NYA | .414 | | Jones,C | KC | .603 |
| Crawford | Bal | .326 | | Cust | Tor | .409 | | Howard,R | Min | .596 |
| Drew,JD | Bos | .324 | | Howard,R | Min | .409 | | Bonds | Tor | .591 |
| Matsui,H | Bal | .324 | | Youkilis | Bos | .408 | | Lee,D | Tor | .581 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Hits vs RHP | | Runs batted in vs RHP | | On-base plus slugging vs RHP |
| | | | | | | | | | | |
| Crawford | Bal | 156 | | Hafner | Bos | 127 | | Hafner | Bos | 1.212 |
| Pujols | NYA | 149 | | Lee,D | Tor | 122 | | Pujols | NYA | 1.060 |
| Martinez,V | Bos | 147 | | Pujols | NYA | 118 | | Bonds | Tor | 1.045 |
| Drew,JD | Bos | 144 | | Lee,Ca | Bos | 107 | | Drew,JD | Bos | 1.010 |
| Lee,D | Tor | 143 | | Sizemore | NYA | 98 | | Ortiz,D | Bal | 1.005 |
| Young,Dlm | Det | 142 | | Jones,Ja | Tex | 95 | | Howard,R | Min | 1.005 |
| DeJesus | LAA | 142 | | Guillen,J | Min | 91 | | Sizemore | NYA | 1.002 |
| Sizemore | NYA | 141 | | Ortiz,D | Bal | 91 | | Jacobs | Oak | 1.001 |
| German,E | Min | 141 | | Ruggiano | Tor | 91 | | Jones,C | KC | .996 |
| Young,M | Bos | 141 | | Votto | LAA | 88 | | Gordon,A | Det | .973 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Doubles vs RHP | | Triples vs RHP | | Homeruns vs RHP |
| | | | | | | | | | | |
| Hafner | Bos | 40 | | Crawford | Bal | 12 | | Hafner | Bos | 39 |
| Helton | KC | 40 | | Drew,S | Det | 10 | | Ortiz,D | Bal | 39 |
| LaRoche,An | Tex | 36 | | Ethier | Sea | 10 | | Pujols | NYA | 35 |
| Drew,JD | Bos | 36 | | Hudson,O | | 8 | | Delgado,C | Sea | 32 |
| Lee,D | Tor | 36 | | Izturis,M | Tam | 8 | | Eldred | Min | 31 |
| Votto | LAA | 34 | | Furcal | Tor | 8 | | Howard,R | Min | 30 |
| Cameron | Oak | 34 | | Sullivan | LAA | 8 | | Bonds | Tor | 30 |
| Young,M | Bos | 33 | | Velez | Tex | 6 | | Lee,D | Tor | 30 |
| Ruggiano | Tor | 32 | | Teahen | Min | 6 | | Swisher | Sea | 29 |
| Bard | Tex | 30 | | Hulett | LAA | 6 | | Guillen,J | Min | 28 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Extra base hits vs RHP | | Total bases vs RHP | | Isolated power vs RHP |
| | | | | | | | | | | |
| Hafner | Bos | 80 | | Hafner | Bos | 297 | | Hafner | Bos | .398 |
| Lee,D | Tor | 69 | | Pujols | NYA | 283 | | Eldred | Min | .380 |
| Pujols | NYA | 64 | | Lee,D | Tor | 275 | | Ortiz,D | Bal | .339 |
| Ortiz,D | Bal | 61 | | Sizemore | NYA | 259 | | Bonds | Tor | .306 |
| Sizemore | NYA | 60 | | Ortiz,D | Bal | 252 | | Jones,C | KC | .306 |
| Drew,JD | Bos | 60 | | Drew,JD | Bos | 250 | | Pujols | NYA | .306 |
| Votto | LAA | 57 | | Crawford | Bal | 241 | | Delgado,C | Sea | .304 |
| LaRoche,An | Tex | 56 | | Lee,Ca | Bos | 239 | | Howard,R | Min | .302 |
| Helton | KC | 55 | | Jones,Ja | Tex | 238 | | Jacobs | Oak | .281 |
| Jones,Ja | Tex | 55 | | Guillen,J | Min | 224 | | Lee,D | Tor | .279 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Walks vs RHP | | Strikeouts vs RHP | | Hit by pitch vs RHP |
| | | | | | | | | | | |
| Bonds | Tor | 116 | | Cameron | Oak | 149 | | Guillen,J | Min | 13 |
| Cust | Tor | 106 | | Ruggiano | Tor | 137 | | Nady | Tex | 13 |
| Drew,JD | Bos | 100 | | Reynolds | Tor | 130 | | Polanco | Tor | 13 |
| Hafner | Bos | 97 | | Cust | Tor | 129 | | Gordon,A | Det | 12 |
| Ortiz,D | Bal | 81 | | Hall,B | Oak | 124 | | German,E | Min | 12 |
| Swisher | Sea | 76 | | Swisher | Sea | 118 | | Doumit | Oak | 10 |
| Delgado,C | Sea | 72 | | Pena,W | | 116 | | Barrett | Min | 10 |
| Helton | KC | 71 | | Lee,D | Tor | 110 | | Gonzalez,E | Tam | 10 |
| Hulett | LAA | 67 | | Peralta,Jh | Min | 109 | | Hunter | KC | 9 |
| Howard,R | Min | 66 | | Hart | ChA | 107 | | Lopez,Jo | Sea | 9 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| Sacrifice bunts vs RHP | | Sacrifice flies vs RHP | | Atbats vs RHP |
| | | | | | | | | | | |
| Polanco | Tor | 10 | | Lee,Ca | Bos | 10 | | Crawford | Bal | 478 |
| Jeter | NYA | 8 | | Pena,W | | 9 | | Polanco | Tor | 476 |
| Molina,J | Sea | 6 | | Young,M | Bos | 8 | | Lee,D | Tor | 473 |
| Ellis | Oak | 6 | | Fielder | Det | 7 | | Young,M | Bos | 471 |
| Iguchi | ChA | 6 | | Hall,B | Oak | 7 | | Cameron | Oak | 469 |
| Furcal | Tor | 5 | | Ramirez,A | Bal | 7 | | Ethier | Sea | 467 |
| Church | Sea | 5 | | Votto | LAA | 7 | | Lee,Ca | Bos | 467 |
| Peralta,Jh | Min | 5 | | Sledge | | 6 | | Ruggiano | Tor | 463 |
| Cabrera,Me | KC | 5 | | Barrett | Min | 6 | | DeJesus | LAA | 461 |
| Lopez,Jo | Sea | 5 | | Matsui,H | Bal | 6 | | Lopez,Jo | Sea | 456 |
| | | | | | | | | | | |
| | | | | | | | | | | |
| AB per homerun vs RHP | | AB per double vs RHP | | Plate appearances vs RHP |
| | | | | | | | | | | |
| Eldred | Min | 9.2 | | Hafner | Bos | 10.0 | | Drew,JD | Bos | 546 |
| Hafner | Bos | 10.3 | | Helton | KC | 10.1 | | Cameron | Oak | 534 |
| Ortiz,D | Bal | 10.5 | | Bard | Tex | 12.1 | | Polanco | Tor | 531 |
| Howard,R | Min | 11.1 | | LaRoche,An | Tex | 12.1 | | Jeter | NYA | 529 |
| Delgado,C | Sea | 12.0 | | Drew,JD | Bos | 12.3 | | Lee,Ca | Bos | 525 |
| Bonds | Tor | 12.3 | | Votto | LAA | 12.9 | | Crawford | Bal | 519 |
| Pujols | NYA | 12.5 | | Lee,D | Tor | 13.1 | | Lee,D | Tor | 519 |
| Jones,C | KC | 12.7 | | Catalanotto | Tam | 13.1 | | Ethier | Sea | 516 |
| Swisher | Sea | 13.4 | | Jacobs | Oak | 13.3 | | Young,M | Bos | 514 |
| Guillen,J | Min | 14.5 | | Cuddyer | Min | 13.6 | | Ruggiano | Tor | 511 |
